|
Name |
Accession |
Description |
Interval |
E-value |
| CitT |
COG0471 |
Di- and tricarboxylate antiporter [Carbohydrate transport and metabolism]; |
91-551 |
9.31e-82 |
|
Di- and tricarboxylate antiporter [Carbohydrate transport and metabolism];
Pssm-ID: 440239 [Multi-domain] Cd Length: 369 Bit Score: 260.47 E-value: 9.31e-82
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 51921291 91 LGSLIVAVAVERWKLHKRVALRMLLFVGTKPSRLMLGFMFVTAFLSMWISNTAATAMMIPIVEAMLQQMiaantaveasl 170
Cdd:COG0471 1 LGGFVLAAALEKTGLGRRIALLLLKRFGGSPLRLLLGLMLATALLSAFISNTARAAMMLPIALSIAAAL----------- 69
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 51921291 171 gtlelldknktselpgsqvvfedpnvqeqEDEETKNMYKAMHLCVCYSASIGGTATLTGTGPNVVLLGQMQELFPDSkdv 250
Cdd:COG0471 70 -----------------------------GSEKRSKFGSALLLPIAFAASIGGMGTLIGTPPNLIAAGLLEEATGIP--- 117
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 51921291 251 LNYASWFGFAFPNMVMMLVLAWLWLqCLYMRHNLKKTciccgekkrdteKIAYKVLNEEYQKLGSLSYPECNVLFCFTLL 330
Cdd:COG0471 118 ISFFEWMLVGLPVALVGLLLLWLVL-YRLLPPEIKEV------------PGSKEVIREELAELGPLSRREKIALAIFALT 184
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 51921291 331 VILWFSRDPgfmpgwlsfawvegntVHITDATVAIFVAILLFIipsqkpkfnfssqteeerktpfypPALLDWKVAQEKV 410
Cdd:COG0471 185 VLLWITGSL----------------HGIPIAVVALLGAVLLLL------------------------TGVLTWKDAYKSI 224
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 51921291 411 PWDIVLLLGGGFAMAKGCETSGLSKWMAAQMEP-LRLVKPAVITLILSCLVAMTTECTSNVATTTLFLPIFASMARSIGI 489
Cdd:COG0471 225 PWGVLLLFGGGLALGAALEKTGLAAWLADALLPlLGGLSPLLLLLLLALLTLLLTEFASNTATAALLLPIAISLAQALGV 304
|
410 420 430 440 450 460
....*....|....*....|....*....|....*....|....*....|....*....|..
gi 51921291 490 HPLYVMIPCTMSASLAFMLPVATPPNAIVFAYGHLRVVDMMKTGLIMNFVGILSVFLSVNTW 551
Cdd:COG0471 305 NPLPLALAVAFAASCAFLLPVGTPPNAIVYGSGYYKFKDFLKVGLPLNLIGLVVLLLLGPLW 366
|
|
| Na_sulph_symp |
pfam00939 |
Sodium:sulfate symporter transmembrane region; There are also some members in this family that ... |
13-558 |
2.73e-77 |
|
Sodium:sulfate symporter transmembrane region; There are also some members in this family that do not match the Prosite motif, and belong to the subfamily SODIT1.
Pssm-ID: 279307 [Multi-domain] Cd Length: 472 Bit Score: 252.29 E-value: 2.73e-77
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 51921291 13 SFAILLFTPILMLPLVILIPDKFARCAYVIVIMAVYWCTDVIPVAVTSLLPVLLFPLLKVLDSKQ----VCIQYMKDTNM 88
Cdd:pfam00939 8 LALLAVLLIILLLPAPDGLPSKAWHLFAIFIATIVGWILEPLPMAVIALFAISLSAILIGTLLAKalswALSGFSSTTTW 87
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 51921291 89 LFLGSLIVAVAVERWKLHKRVALRMLLFVGTKPsrLMLGFMFVTAFLSMWISNTAATAMMIPIVEAMLQQMIAANtavea 168
Cdd:pfam00939 88 LVFGAFFISAAFEKTGLGRRIALVLVKKMGKRT--LGLGYGLVFSDLLLAPATPSNTARAGGIVFPIIMSLPPAF----- 160
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 51921291 169 slgtlelldknktselpGSQVvfedpnvqeqEDEETKNMYKAMHLCVCYSASIGGTATLTGTGPNVVLLGQMQELfpdSK 248
Cdd:pfam00939 161 -----------------GSDP----------EKGSERRIGAYLMWTVYQSTSITSAMFLTAMAPNLLLLGLMNSI---LG 210
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 51921291 249 DVLNYASWFGFAFPNMVMMLVLAWLWLQCLYMrhnlkktciccGEKKRDTEkiAYKVLNEEYQKLGSLSYPECNVLFCFT 328
Cdd:pfam00939 211 VTITWASWFLAAIPPGVILLLLAPLLLYVLYP-----------PEIKSVPD--AKAIAKTELKELGPMTFREKALLGLFV 277
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 51921291 329 LLVILWFSrdpgfmpgwlsfawveGNTVHITDATVAIFVAILLFIIPsqkpkfnfssqteeerktpfyppaLLDWK-VAQ 407
Cdd:pfam00939 278 LLLLLWIF----------------GGSLNIDATTVAIIGLALMLLLR------------------------ILDWKdIVK 317
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 51921291 408 EKVPWDIVLLLGGGFAMAKGCETSGLSKWMAAQMEPL--RLVKPAVITLILSCLVAMTTECTSNVATTTLFLPIFASMAR 485
Cdd:pfam00939 318 NKGAWNTLIWLGGLIMLANGLERSGFIEWLGNTLSTSlsGFSPAMAFIIILSLFYLSHYLFASATAHTAAMLPIFAAVAQ 397
|
490 500 510 520 530 540 550
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 51921291 486 SI-GIHPLYVMIPCTMSASLA-FMLPVATPPNAIVFAYGHLRVVDMMKTGLIMNFVGILSVFLSVNTWGRAMFNL 558
Cdd:pfam00939 398 AIpGAPPLLAALLLGFAISLGgFLTPYGTGPGPIYFGSGYLKVKDWWRIGAILTIIGLLILLLLGNWWWKPLGSL 472
|
|
| SLC13_permease |
cd01115 |
Permease SLC13 (solute carrier 13). The sodium/dicarboxylate cotransporter NaDC-1 has been ... |
39-548 |
7.03e-64 |
|
Permease SLC13 (solute carrier 13). The sodium/dicarboxylate cotransporter NaDC-1 has been shown to translocate Krebs cycle intermediates such as succinate, citrate, and alpha-ketoglutarate across plasma membranes rabbit, human, and rat kidney. It is related to renal and intestinal Na+/sulfate cotransporters and a few putative bacterial permeases. The SLC13-type proteins belong to the ArsB/NhaD superfamily of permeases that translocate sodium and various anions across biological membranes in all three kingdoms of life. A typical ArsB/NhaD permease is composed of 8-13 transmembrane helices.
Pssm-ID: 238535 [Multi-domain] Cd Length: 382 Bit Score: 213.99 E-value: 7.03e-64
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 51921291 39 AYVIVIMAVYWCTDVIPVAVTSLLPVLLFPLLKVLDSKQVCIQYMKDTNMLFLGSLIVAVAVERWKLHKRVALRMLLFVG 118
Cdd:cd01115 1 LAILVFAAVLFVTEALPLDVTALLVPVLLVLLGVVPPKEAFSGFSDPAVILFLAGFILGAALTRTGLAKRIATKLLKRAG 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 51921291 119 TKPSRLMLGFMFVTAFLSMWISNTAATAMMIPIVEAMLQQMIAANtaveaslgtlelldknktselpgsqvvfedpnvqe 198
Cdd:cd01115 81 KGERRLLLLLMLVTAFLSAFMSNTATVAIMLPVALGLAAKLDISP----------------------------------- 125
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 51921291 199 qedeetknmyKAMHLCVCYSASIGGTATLTGTGPNVVLLGQMQELFPDSkdvLNYASWFGFAFPNMVMMLVLAWLWLQcl 278
Cdd:cd01115 126 ----------SRLLMPLAFAASIGGMLTLIGTPPNLVASGYLESLGGQG---FSFFEFTPIGLPLLIIGLLYLWFIFR-- 190
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 51921291 279 ymrhnlkktciccgekkrdtekiaykvlneeyqklgslsypecNVLFCFTLLVILWFSRDPGFMPgwlsfawvegntVHI 358
Cdd:cd01115 191 -------------------------------------------LAVLIITIVLLAALAAITGLLP------------VSV 215
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 51921291 359 TDATVAIFVAILlfiipsqkpkfnfssqteeerktpfyppALLDWKVAQEKVPWDIVLLLGGGFAMAKGCETSGLSKWMA 438
Cdd:cd01115 216 AIAIGAIVLVFG----------------------------GVLLTKEDYKSIDWGIIFLFAGGIPLGKALESSGAAALIA 267
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 51921291 439 AQMEPLRLVKPAVITLILSCLVAMT-TECTSNVATTTLFLPIFASMARSIGIHPLYVMIPCTMSASLAFMLPVATPPNAI 517
Cdd:cd01115 268 EALISLLGGLPPFAILLLLCLLTLVlTNFISNTATAVLLAPIALSIALSLGLPPEALLLAVAIGASCAFMLPVGTPPNAI 347
|
490 500 510
....*....|....*....|....*....|.
gi 51921291 518 VFAYGHLRVVDMMKTGLIMNfvgILSVFLSV 548
Cdd:cd01115 348 VLGPGGYKFSDFAKVGLPLS---ILSLVVSV 375
|
|
| dass |
TIGR00785 |
anion transporter; The Divalent Anion:Na+ Symporter (DASS) Family (TC 2.A.47) Functionally ... |
41-551 |
6.22e-45 |
|
anion transporter; The Divalent Anion:Na+ Symporter (DASS) Family (TC 2.A.47) Functionally characterized proteins of the DASS family transport (1) organic di- and tricarboxylates of the Krebs Cycle as well as dicarboxylate amino acid, (2) inorganic sulfate and (3) phosphate. The animal NaDC-1 cotransport 3 Na+ with each dicarboxylate. Protonated tricarboxylates are also cotransported with 3Na+. [Transport and binding proteins, Anions, Transport and binding proteins, Cations and iron carrying compounds]
Pssm-ID: 273267 [Multi-domain] Cd Length: 444 Bit Score: 164.82 E-value: 6.22e-45
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 51921291 41 VIVIMAVYWCTDVIPVAVTSLLPVLLFP----LLKVLDSKQVCIQYMKDTNMLFLGSLIVAVAVERWKLHKRVALRMLLF 116
Cdd:TIGR00785 16 IFVAAIVGWILEPLPLPVTALLAIPIIAvllgVLSAFKFKNALSGFADPTIWLFFGAFILATALVKTGLGKRIAYKLVGK 95
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 51921291 117 VGTKPSRL-MLGFMFVTAFLSMWISNTA-ATAMMIPIVEAMLQQMiaantaveaslgtlelldknktselpgsqvvfedp 194
Cdd:TIGR00785 96 MGGTTLGLgYFLVFLETLLAPMWPSNTArAGGILLPIIKSLLPLL----------------------------------- 140
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 51921291 195 nvQEQEDEETKNMYKAMHLCVCYSASIGGTATLTGTGPNVVLLGQMqelFPDSKDVLNYASWFGFAFPNMVMMLVLAWLW 274
Cdd:TIGR00785 141 --GSKPEKSPRKIGKYLMLGIAYSASIGSSGFLTGSAPNALAAGIL---SKILGIQISWGDWFLAGLPLGIILLLLVPLL 215
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 51921291 275 LQCLYmRHNLKKtciccgekKRDTEKIAykvlNEEYQKLGSLSYPEcnvlfcFTLLVILWFSRDPgfmpgwlsfaWVEGN 354
Cdd:TIGR00785 216 LYVLF-PPELKL--------KDEVDLWA----KEELEEMGPMSFRE------KALLGIFLLALLL----------WIFGG 266
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 51921291 355 TVHITDATVAIFVAILLFIIpsqkpkfnfssqteeerktpfyppALLDWK-VAQEKVPWDIVLLLGGGFAMAKGCETSGL 433
Cdd:TIGR00785 267 SLGINASVVALLAVVLMLFL------------------------GIVTWKdIQKNKVAWNTLILFGGLIGLAGGLKKSGF 322
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 51921291 434 SKWMAAQMEP--LRLVKPAVITLILSCLVAMTTECTSNVATTTLFLPIFASMARSIGIHPLYVMIPCTMSASLA-FMLPV 510
Cdd:TIGR00785 323 IKWFSEKLVGilDGLSPTIAVLVLVVLFYIILYFFASNTAHTAALVPIFFSVASAQGIPLELLALALALSASLMgFLTPY 402
|
490 500 510 520
....*....|....*....|....*....|....*....|.
gi 51921291 511 ATPPNAIVFAYGHLRVVDMMKTGLIMNFVGILsVFLSVNTW 551
Cdd:TIGR00785 403 ATPPNAIAYGSGYVKIKDMWRVGAIIGIVGLI-VLLLVGTL 442
|
|
| CitMHS |
pfam03600 |
Citrate transporter; |
11-163 |
4.31e-05 |
|
Citrate transporter;
Pssm-ID: 460985 [Multi-domain] Cd Length: 342 Bit Score: 45.77 E-value: 4.31e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 51921291 11 FKSFAILLFTPILMLPLVILIPDKFARCAYVIVIMAVYWCTDVIPVAVTSLLPVLLFPLLKVLDSKQVCIQYMKDTNMLF 90
Cdd:pfam03600 181 FRKLLPVRKEEEAELEELRKRAIKDKLLLAISALVLALVILGFLLLSVLALAGALLLLLTGVLDPEEALKAVDWSTLLFF 260
|
90 100 110 120 130 140 150
....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 51921291 91 LGSLIVAVAVERWKLHKRVALRMLLFVGtkPSRLMLGFMFVTAFLSMWISNTAATAMMIPIVEAMLQQMIAAN 163
Cdd:pfam03600 261 AGLFILVGALEKTGLADALADALGGLSG--LLVALALILWLSALLSAFISNVPTAALMAPIIVGMAPAAGLGD 331
|
|
| SLC13_permease |
cd01115 |
Permease SLC13 (solute carrier 13). The sodium/dicarboxylate cotransporter NaDC-1 has been ... |
11-166 |
1.16e-04 |
|
Permease SLC13 (solute carrier 13). The sodium/dicarboxylate cotransporter NaDC-1 has been shown to translocate Krebs cycle intermediates such as succinate, citrate, and alpha-ketoglutarate across plasma membranes rabbit, human, and rat kidney. It is related to renal and intestinal Na+/sulfate cotransporters and a few putative bacterial permeases. The SLC13-type proteins belong to the ArsB/NhaD superfamily of permeases that translocate sodium and various anions across biological membranes in all three kingdoms of life. A typical ArsB/NhaD permease is composed of 8-13 transmembrane helices.
Pssm-ID: 238535 [Multi-domain] Cd Length: 382 Bit Score: 44.50 E-value: 1.16e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 51921291 11 FKSFAILLFTPILMLPLVILIP-----DKFARCAYVIVIMAV-YWCTDVIPVAVTSLLPVLLFPLLKVLDSKQVCIQYMK 84
Cdd:cd01115 162 GQGFSFFEFTPIGLPLLIIGLLylwfiFRLAVLIITIVLLAAlAAITGLLPVSVAIAIGAIVLVFGGVLLTKEDYKSIDW 241
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 51921291 85 DTNMLFLGSLIVAVAVERWKLHKRVALRMLLFVGTKPSRLMLG-FMFVTAFLSMWISNTAATAMMIPIVEAMLQQMIAAN 163
Cdd:cd01115 242 GIIFLFAGGIPLGKALESSGAAALIAEALISLLGGLPPFAILLlLCLLTLVLTNFISNTATAVLLAPIALSIALSLGLPP 321
|
...
gi 51921291 164 TAV 166
Cdd:cd01115 322 EAL 324
|
|
| |
|
Name |
Accession |
Description |
Interval |
E-value |
| CitT |
COG0471 |
Di- and tricarboxylate antiporter [Carbohydrate transport and metabolism]; |
91-551 |
9.31e-82 |
|
Di- and tricarboxylate antiporter [Carbohydrate transport and metabolism];
Pssm-ID: 440239 [Multi-domain] Cd Length: 369 Bit Score: 260.47 E-value: 9.31e-82
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 51921291 91 LGSLIVAVAVERWKLHKRVALRMLLFVGTKPSRLMLGFMFVTAFLSMWISNTAATAMMIPIVEAMLQQMiaantaveasl 170
Cdd:COG0471 1 LGGFVLAAALEKTGLGRRIALLLLKRFGGSPLRLLLGLMLATALLSAFISNTARAAMMLPIALSIAAAL----------- 69
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 51921291 171 gtlelldknktselpgsqvvfedpnvqeqEDEETKNMYKAMHLCVCYSASIGGTATLTGTGPNVVLLGQMQELFPDSkdv 250
Cdd:COG0471 70 -----------------------------GSEKRSKFGSALLLPIAFAASIGGMGTLIGTPPNLIAAGLLEEATGIP--- 117
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 51921291 251 LNYASWFGFAFPNMVMMLVLAWLWLqCLYMRHNLKKTciccgekkrdteKIAYKVLNEEYQKLGSLSYPECNVLFCFTLL 330
Cdd:COG0471 118 ISFFEWMLVGLPVALVGLLLLWLVL-YRLLPPEIKEV------------PGSKEVIREELAELGPLSRREKIALAIFALT 184
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 51921291 331 VILWFSRDPgfmpgwlsfawvegntVHITDATVAIFVAILLFIipsqkpkfnfssqteeerktpfypPALLDWKVAQEKV 410
Cdd:COG0471 185 VLLWITGSL----------------HGIPIAVVALLGAVLLLL------------------------TGVLTWKDAYKSI 224
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 51921291 411 PWDIVLLLGGGFAMAKGCETSGLSKWMAAQMEP-LRLVKPAVITLILSCLVAMTTECTSNVATTTLFLPIFASMARSIGI 489
Cdd:COG0471 225 PWGVLLLFGGGLALGAALEKTGLAAWLADALLPlLGGLSPLLLLLLLALLTLLLTEFASNTATAALLLPIAISLAQALGV 304
|
410 420 430 440 450 460
....*....|....*....|....*....|....*....|....*....|....*....|..
gi 51921291 490 HPLYVMIPCTMSASLAFMLPVATPPNAIVFAYGHLRVVDMMKTGLIMNFVGILSVFLSVNTW 551
Cdd:COG0471 305 NPLPLALAVAFAASCAFLLPVGTPPNAIVYGSGYYKFKDFLKVGLPLNLIGLVVLLLLGPLW 366
|
|
| Na_sulph_symp |
pfam00939 |
Sodium:sulfate symporter transmembrane region; There are also some members in this family that ... |
13-558 |
2.73e-77 |
|
Sodium:sulfate symporter transmembrane region; There are also some members in this family that do not match the Prosite motif, and belong to the subfamily SODIT1.
Pssm-ID: 279307 [Multi-domain] Cd Length: 472 Bit Score: 252.29 E-value: 2.73e-77
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 51921291 13 SFAILLFTPILMLPLVILIPDKFARCAYVIVIMAVYWCTDVIPVAVTSLLPVLLFPLLKVLDSKQ----VCIQYMKDTNM 88
Cdd:pfam00939 8 LALLAVLLIILLLPAPDGLPSKAWHLFAIFIATIVGWILEPLPMAVIALFAISLSAILIGTLLAKalswALSGFSSTTTW 87
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 51921291 89 LFLGSLIVAVAVERWKLHKRVALRMLLFVGTKPsrLMLGFMFVTAFLSMWISNTAATAMMIPIVEAMLQQMIAANtavea 168
Cdd:pfam00939 88 LVFGAFFISAAFEKTGLGRRIALVLVKKMGKRT--LGLGYGLVFSDLLLAPATPSNTARAGGIVFPIIMSLPPAF----- 160
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 51921291 169 slgtlelldknktselpGSQVvfedpnvqeqEDEETKNMYKAMHLCVCYSASIGGTATLTGTGPNVVLLGQMQELfpdSK 248
Cdd:pfam00939 161 -----------------GSDP----------EKGSERRIGAYLMWTVYQSTSITSAMFLTAMAPNLLLLGLMNSI---LG 210
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 51921291 249 DVLNYASWFGFAFPNMVMMLVLAWLWLQCLYMrhnlkktciccGEKKRDTEkiAYKVLNEEYQKLGSLSYPECNVLFCFT 328
Cdd:pfam00939 211 VTITWASWFLAAIPPGVILLLLAPLLLYVLYP-----------PEIKSVPD--AKAIAKTELKELGPMTFREKALLGLFV 277
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 51921291 329 LLVILWFSrdpgfmpgwlsfawveGNTVHITDATVAIFVAILLFIIPsqkpkfnfssqteeerktpfyppaLLDWK-VAQ 407
Cdd:pfam00939 278 LLLLLWIF----------------GGSLNIDATTVAIIGLALMLLLR------------------------ILDWKdIVK 317
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 51921291 408 EKVPWDIVLLLGGGFAMAKGCETSGLSKWMAAQMEPL--RLVKPAVITLILSCLVAMTTECTSNVATTTLFLPIFASMAR 485
Cdd:pfam00939 318 NKGAWNTLIWLGGLIMLANGLERSGFIEWLGNTLSTSlsGFSPAMAFIIILSLFYLSHYLFASATAHTAAMLPIFAAVAQ 397
|
490 500 510 520 530 540 550
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 51921291 486 SI-GIHPLYVMIPCTMSASLA-FMLPVATPPNAIVFAYGHLRVVDMMKTGLIMNFVGILSVFLSVNTWGRAMFNL 558
Cdd:pfam00939 398 AIpGAPPLLAALLLGFAISLGgFLTPYGTGPGPIYFGSGYLKVKDWWRIGAILTIIGLLILLLLGNWWWKPLGSL 472
|
|
| SLC13_permease |
cd01115 |
Permease SLC13 (solute carrier 13). The sodium/dicarboxylate cotransporter NaDC-1 has been ... |
39-548 |
7.03e-64 |
|
Permease SLC13 (solute carrier 13). The sodium/dicarboxylate cotransporter NaDC-1 has been shown to translocate Krebs cycle intermediates such as succinate, citrate, and alpha-ketoglutarate across plasma membranes rabbit, human, and rat kidney. It is related to renal and intestinal Na+/sulfate cotransporters and a few putative bacterial permeases. The SLC13-type proteins belong to the ArsB/NhaD superfamily of permeases that translocate sodium and various anions across biological membranes in all three kingdoms of life. A typical ArsB/NhaD permease is composed of 8-13 transmembrane helices.
Pssm-ID: 238535 [Multi-domain] Cd Length: 382 Bit Score: 213.99 E-value: 7.03e-64
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 51921291 39 AYVIVIMAVYWCTDVIPVAVTSLLPVLLFPLLKVLDSKQVCIQYMKDTNMLFLGSLIVAVAVERWKLHKRVALRMLLFVG 118
Cdd:cd01115 1 LAILVFAAVLFVTEALPLDVTALLVPVLLVLLGVVPPKEAFSGFSDPAVILFLAGFILGAALTRTGLAKRIATKLLKRAG 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 51921291 119 TKPSRLMLGFMFVTAFLSMWISNTAATAMMIPIVEAMLQQMIAANtaveaslgtlelldknktselpgsqvvfedpnvqe 198
Cdd:cd01115 81 KGERRLLLLLMLVTAFLSAFMSNTATVAIMLPVALGLAAKLDISP----------------------------------- 125
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 51921291 199 qedeetknmyKAMHLCVCYSASIGGTATLTGTGPNVVLLGQMQELFPDSkdvLNYASWFGFAFPNMVMMLVLAWLWLQcl 278
Cdd:cd01115 126 ----------SRLLMPLAFAASIGGMLTLIGTPPNLVASGYLESLGGQG---FSFFEFTPIGLPLLIIGLLYLWFIFR-- 190
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 51921291 279 ymrhnlkktciccgekkrdtekiaykvlneeyqklgslsypecNVLFCFTLLVILWFSRDPGFMPgwlsfawvegntVHI 358
Cdd:cd01115 191 -------------------------------------------LAVLIITIVLLAALAAITGLLP------------VSV 215
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 51921291 359 TDATVAIFVAILlfiipsqkpkfnfssqteeerktpfyppALLDWKVAQEKVPWDIVLLLGGGFAMAKGCETSGLSKWMA 438
Cdd:cd01115 216 AIAIGAIVLVFG----------------------------GVLLTKEDYKSIDWGIIFLFAGGIPLGKALESSGAAALIA 267
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 51921291 439 AQMEPLRLVKPAVITLILSCLVAMT-TECTSNVATTTLFLPIFASMARSIGIHPLYVMIPCTMSASLAFMLPVATPPNAI 517
Cdd:cd01115 268 EALISLLGGLPPFAILLLLCLLTLVlTNFISNTATAVLLAPIALSIALSLGLPPEALLLAVAIGASCAFMLPVGTPPNAI 347
|
490 500 510
....*....|....*....|....*....|.
gi 51921291 518 VFAYGHLRVVDMMKTGLIMNfvgILSVFLSV 548
Cdd:cd01115 348 VLGPGGYKFSDFAKVGLPLS---ILSLVVSV 375
|
|
| dass |
TIGR00785 |
anion transporter; The Divalent Anion:Na+ Symporter (DASS) Family (TC 2.A.47) Functionally ... |
41-551 |
6.22e-45 |
|
anion transporter; The Divalent Anion:Na+ Symporter (DASS) Family (TC 2.A.47) Functionally characterized proteins of the DASS family transport (1) organic di- and tricarboxylates of the Krebs Cycle as well as dicarboxylate amino acid, (2) inorganic sulfate and (3) phosphate. The animal NaDC-1 cotransport 3 Na+ with each dicarboxylate. Protonated tricarboxylates are also cotransported with 3Na+. [Transport and binding proteins, Anions, Transport and binding proteins, Cations and iron carrying compounds]
Pssm-ID: 273267 [Multi-domain] Cd Length: 444 Bit Score: 164.82 E-value: 6.22e-45
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 51921291 41 VIVIMAVYWCTDVIPVAVTSLLPVLLFP----LLKVLDSKQVCIQYMKDTNMLFLGSLIVAVAVERWKLHKRVALRMLLF 116
Cdd:TIGR00785 16 IFVAAIVGWILEPLPLPVTALLAIPIIAvllgVLSAFKFKNALSGFADPTIWLFFGAFILATALVKTGLGKRIAYKLVGK 95
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 51921291 117 VGTKPSRL-MLGFMFVTAFLSMWISNTA-ATAMMIPIVEAMLQQMiaantaveaslgtlelldknktselpgsqvvfedp 194
Cdd:TIGR00785 96 MGGTTLGLgYFLVFLETLLAPMWPSNTArAGGILLPIIKSLLPLL----------------------------------- 140
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 51921291 195 nvQEQEDEETKNMYKAMHLCVCYSASIGGTATLTGTGPNVVLLGQMqelFPDSKDVLNYASWFGFAFPNMVMMLVLAWLW 274
Cdd:TIGR00785 141 --GSKPEKSPRKIGKYLMLGIAYSASIGSSGFLTGSAPNALAAGIL---SKILGIQISWGDWFLAGLPLGIILLLLVPLL 215
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 51921291 275 LQCLYmRHNLKKtciccgekKRDTEKIAykvlNEEYQKLGSLSYPEcnvlfcFTLLVILWFSRDPgfmpgwlsfaWVEGN 354
Cdd:TIGR00785 216 LYVLF-PPELKL--------KDEVDLWA----KEELEEMGPMSFRE------KALLGIFLLALLL----------WIFGG 266
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 51921291 355 TVHITDATVAIFVAILLFIIpsqkpkfnfssqteeerktpfyppALLDWK-VAQEKVPWDIVLLLGGGFAMAKGCETSGL 433
Cdd:TIGR00785 267 SLGINASVVALLAVVLMLFL------------------------GIVTWKdIQKNKVAWNTLILFGGLIGLAGGLKKSGF 322
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 51921291 434 SKWMAAQMEP--LRLVKPAVITLILSCLVAMTTECTSNVATTTLFLPIFASMARSIGIHPLYVMIPCTMSASLA-FMLPV 510
Cdd:TIGR00785 323 IKWFSEKLVGilDGLSPTIAVLVLVVLFYIILYFFASNTAHTAALVPIFFSVASAQGIPLELLALALALSASLMgFLTPY 402
|
490 500 510 520
....*....|....*....|....*....|....*....|.
gi 51921291 511 ATPPNAIVFAYGHLRVVDMMKTGLIMNFVGILsVFLSVNTW 551
Cdd:TIGR00785 403 ATPPNAIAYGSGYVKIKDMWRVGAIIGIVGLI-VLLLVGTL 442
|
|
| ArsB_NhaD_permease |
cd00625 |
Anion permease ArsB/NhaD. These permeases have been shown to translocate sodium, arsenate, ... |
46-542 |
1.64e-34 |
|
Anion permease ArsB/NhaD. These permeases have been shown to translocate sodium, arsenate, antimonite, sulfate and organic anions across biological membranes in all three kingdoms of life. A typical anion permease contains 8-13 transmembrane helices and can function either independently as a chemiosmotic transporter or as a channel-forming subunit of an ATP-driven anion pump.
Pssm-ID: 238344 [Multi-domain] Cd Length: 396 Bit Score: 134.68 E-value: 1.64e-34
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 51921291 46 AVYWCTDVIPVAVTSLLPVLLFPLLKVLDSKQVCIQYMKDTNMLFLGSLIVAVAVERWKLHKRVALRMLLFvGTKPSRLM 125
Cdd:cd00625 1 YVLIRPEKLPRAVVALLGAVLLVLLGVVSPKEALSAIDWETILLLFGMMILSAALEETGLFDRLAAKLARA-SKGSRRLL 79
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 51921291 126 LGFMFVTAFLSMWISNTAATAMMIPIVEAMLQQMIAANTaveaslgtlelldknktselpgsqvvfedpnvqeqedeetk 205
Cdd:cd00625 80 LLLMLLTAALSAFFSNDATAVLLTPIVLALLRKLGLSPP----------------------------------------- 118
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 51921291 206 nmyKAMHLCVCYSASIGGTATLTGTGPNVVLLGQMQelfpdskdvLNYASWFGFAFPNMVMMLVLAWLWLQCLYMRHNLK 285
Cdd:cd00625 119 ---VPLLLALAFAANIGGAATPIGNPPNLIIASLSG---------LGFLDFLAFMAPPALGLLLLLLGLLYLLFRKKLLL 186
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 51921291 286 KtciccgekKRDTEKIAYKVLNEEYQKLGSLSYpecnVLFCFTLLVILWFSrdpGFMPGWlsfawvegntvhITDATVAI 365
Cdd:cd00625 187 P--------DEDKLTVLAEPLPARPLLKKFLLL----ALLLLLLFVLLFFF---LIPLGL------------IALLGALL 239
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 51921291 366 FVAILLFIipsqkpkfnfssqteeerktpfyppalLDWKVAQEKVPWDIVLLLGGGFAMAKGCETSGLSKWMAAQMEPLR 445
Cdd:cd00625 240 LLLLLVRG---------------------------LDPEEVLKSVDWGTLLFFAGLFVLVGALESTGLLEWLAELLVALV 292
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 51921291 446 LVKPAVITLILSCLVAMTTECTSNVATTTLFLPIFASMAR-----SIGIHPLYVMIPCTMSASLAFMLPVATPPNAIVfa 520
Cdd:cd00625 293 GLPPLAALLLIGLLSALLSNFISNVPTVALLLPIAASLAPpepawLALALGSTLGGNLTLIGSLANLIPLGAAENAGV-- 370
|
490 500
....*....|....*....|..
gi 51921291 521 ygHLRVVDMMKTGLIMNFVGIL 542
Cdd:cd00625 371 --GISFGEFLKVGLPLTLLSLV 390
|
|
| CitMHS |
pfam03600 |
Citrate transporter; |
46-496 |
5.62e-22 |
|
Citrate transporter;
Pssm-ID: 460985 [Multi-domain] Cd Length: 342 Bit Score: 97.38 E-value: 5.62e-22
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 51921291 46 AVYWCTDVIPVAVTSLLPVLLFPLLKVLDSKQVCIQYMKDTNMLFLGSLIVAVAVERWKLHKRVALRMLLFVGTKPSRLM 125
Cdd:pfam03600 1 YVLIITEKLPRDVVALLGAVLLVLLGVLTPEEALSGIDSPTILLLLGMMIIGAILERTGLFDRLALKLLRLAGGKPRRLL 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 51921291 126 LGFMFVTAFLSMWISNTAATAMMIPIVeamlqqmiaantaveaslgtLELLDKNKTSELPgsqvvfedpnvqeqedeetk 205
Cdd:pfam03600 81 VALMLATALLSAFLSNDGTVLIMIPIV--------------------LALARRLGLPPSP-------------------- 120
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 51921291 206 nmykaMHLCVCYSASIGGTATLTGTGPNVVLLGQMQELFPDskdvlnyaswFGFAFPNMVMMLVLAWLWLQCLYMRHNLK 285
Cdd:pfam03600 121 -----LLIALAFAANIGGTATPIGDPPNIIIASALGLSFGD----------FGFFMFPPVGVALLLVGLLPLLLIFRKLL 185
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 51921291 286 KTCICCGEKKRDTEKIAYKVLneeyqklgslsypecnVLFCFTLLVILwfsrdpgfmpgwlsfAWVEGNTVHITDATVAI 365
Cdd:pfam03600 186 PVRKEEEAELEELRKRAIKDK----------------LLLAISALVLA---------------LVILGFLLLSVLALAGA 234
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 51921291 366 FVAILLFIIpsqkpkfnfssqteeerktpfyppallDWKVAQEKVPWDIVLLLGGGFAMAKGCETSGLSKWMAAQMEPlr 445
Cdd:pfam03600 235 LLLLLTGVL---------------------------DPEEALKAVDWSTLLFFAGLFILVGALEKTGLADALADALGG-- 285
|
410 420 430 440 450
....*....|....*....|....*....|....*....|....*....|.
gi 51921291 446 LVKPAVITLILSCLVAMTTECTSNVATTTLFLPIFASMARSIGIHPLYVMI 496
Cdd:pfam03600 286 LSGLLVALALILWLSALLSAFISNVPTAALMAPIIVGMAPAAGLGDPDPLA 336
|
|
| CitMHS |
pfam03600 |
Citrate transporter; |
397-546 |
2.02e-09 |
|
Citrate transporter;
Pssm-ID: 460985 [Multi-domain] Cd Length: 342 Bit Score: 59.25 E-value: 2.02e-09
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 51921291 397 PPALLDWKVAQEKVPWDIVLLLGGGFAMAKGCETSGLSKWMAAQMEPLRLVKPAVITLILSCLVAMTTECTSNVATTTLF 476
Cdd:pfam03600 24 LLGVLTPEEALSGIDSPTILLLLGMMIIGAILERTGLFDRLALKLLRLAGGKPRRLLVALMLATALLSAFLSNDGTVLIM 103
|
90 100 110 120 130 140 150
....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 51921291 477 LPIFASMARSIGIHPLYVMIPCTMSASLAFML-PVATPPNAIVFAYGHLRVVDMMKTGLIMNFVGILSVFL 546
Cdd:pfam03600 104 IPIVLALARRLGLPPSPLLIALAFAANIGGTAtPIGDPPNIIIASALGLSFGDFGFFMFPPVGVALLLVGL 174
|
|
| ArsB_NhaD_permease |
cd00625 |
Anion permease ArsB/NhaD. These permeases have been shown to translocate sodium, arsenate, ... |
412-546 |
3.43e-09 |
|
Anion permease ArsB/NhaD. These permeases have been shown to translocate sodium, arsenate, antimonite, sulfate and organic anions across biological membranes in all three kingdoms of life. A typical anion permease contains 8-13 transmembrane helices and can function either independently as a chemiosmotic transporter or as a channel-forming subunit of an ATP-driven anion pump.
Pssm-ID: 238344 [Multi-domain] Cd Length: 396 Bit Score: 58.80 E-value: 3.43e-09
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 51921291 412 WDIVLLLGGGFAMAKGCETSGLSKWMAAQMEpLRLVKPAVITLILSCLVAMTTECTSNVATTTLFLPIFASMARSIGI-H 490
Cdd:cd00625 39 WETILLLFGMMILSAALEETGLFDRLAAKLA-RASKGSRRLLLLLMLLTAALSAFFSNDATAVLLTPIVLALLRKLGLsP 117
|
90 100 110 120 130
....*....|....*....|....*....|....*....|....*....|....*..
gi 51921291 491 PLYVMIPCTMSASLA-FMLPVATPPNAIVFAYGHLRVVDMMKTGLIMNFVGILSVFL 546
Cdd:cd00625 118 PVPLLLALAFAANIGgAATPIGNPPNLIIASLSGLGFLDFLAFMAPPALGLLLLLLG 174
|
|
| ArsB |
COG1055 |
Na+/H+ antiporter NhaD or related arsenite permease [Inorganic ion transport and metabolism]; |
361-546 |
1.09e-06 |
|
Na+/H+ antiporter NhaD or related arsenite permease [Inorganic ion transport and metabolism];
Pssm-ID: 440675 [Multi-domain] Cd Length: 415 Bit Score: 51.28 E-value: 1.09e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 51921291 361 ATVAIFVAILLFIIpSQKPKFNFSSqteeerktpfypPALL-----------DWKVAQEKVPWDIVLLLGGGFAMAKGCE 429
Cdd:COG1055 4 LALAIFVLTYLLII-LEPRGLNRAV------------AALLgaalllllgvvSLEDALEAIDWNTILFLLGMMIIVAILD 70
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 51921291 430 TSGLSKWMAAQMEPLRLVKPAVITLILSCLVAMTTECTSNVATTTLFLPIFASMARSIGIHPLYVMIPCTMSASLA-FML 508
Cdd:COG1055 71 ESGFFEWLAIKLARRAKGSPRRLLWLLGLLTALLSAFLDNDTTALLLTPVVLAIARRLGLNPVPFLIAIVFAANIGgAAT 150
|
170 180 190
....*....|....*....|....*....|....*...
gi 51921291 509 PVATPPNAIVFAYGHLRVVDMMKTGLIMNFVGILSVFL 546
Cdd:COG1055 151 PIGNPTNIMIASAGGLSFLDFLANLFPPSLVSLLVTLL 188
|
|
| ArsB |
COG1055 |
Na+/H+ antiporter NhaD or related arsenite permease [Inorganic ion transport and metabolism]; |
85-493 |
1.28e-05 |
|
Na+/H+ antiporter NhaD or related arsenite permease [Inorganic ion transport and metabolism];
Pssm-ID: 440675 [Multi-domain] Cd Length: 415 Bit Score: 47.82 E-value: 1.28e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 51921291 85 DTNMLFLGSLIVAVAVERWKLHKRVALRMLLFVGTKPSRLMLGFMFVTAFLSMWISNTAATAMMIPIVEAMLQQM----- 159
Cdd:COG1055 54 NTILFLLGMMIIVAILDESGFFEWLAIKLARRAKGSPRRLLWLLGLLTALLSAFLDNDTTALLLTPVVLAIARRLglnpv 133
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 51921291 160 -------IAANTAveaSLGTLelldknktselpgsqvvFEDPnvqeqedeetknmykamhlcvcysasiggtatltgtgP 232
Cdd:COG1055 134 pfliaivFAANIG---GAATP-----------------IGNP-------------------------------------T 156
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 51921291 233 NVVLLGQMQelfpdskdvLNYASWFGFAFPNMVMMLVLAWLWLqCLYMRHNLKKTCIccgEKKRDTEKIAYKVLneeyqk 312
Cdd:COG1055 157 NIMIASAGG---------LSFLDFLANLFPPSLVSLLVTLLVL-YLLFRKELPAAPD---LEDDPKEAIKDRRL------ 217
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 51921291 313 lgslsypeCNVLFCFTLLVILWFsrdpgfmpgwlsfawVEGNTVHITDATVAIFVAILLFIIpsqkpkfnfssqteeerk 392
Cdd:COG1055 218 --------LRISLLVLALLLVGF---------------VLHSFLGLPPALIALLGAAVLLLL------------------ 256
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 51921291 393 TPFYPPALLdwkvaqEKVPWDIVLLLGGGFAMAKGCETSGLSKWMAAQMEPLRLVKPAVITLILSCLVAMTTECTSNVAT 472
Cdd:COG1055 257 ARVDVREVL------KKVDWSTLLFFIGLFVVVGGLENTGLLDLLAELLASLTGGNLLLAALLILWLSAILSAVVDNVPL 330
|
410 420
....*....|....*....|.
gi 51921291 473 TTLFLPIFASMARSIGIHPLY 493
Cdd:COG1055 331 VAALLPLIPDLGATGNPEPLW 351
|
|
| CitMHS |
pfam03600 |
Citrate transporter; |
11-163 |
4.31e-05 |
|
Citrate transporter;
Pssm-ID: 460985 [Multi-domain] Cd Length: 342 Bit Score: 45.77 E-value: 4.31e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 51921291 11 FKSFAILLFTPILMLPLVILIPDKFARCAYVIVIMAVYWCTDVIPVAVTSLLPVLLFPLLKVLDSKQVCIQYMKDTNMLF 90
Cdd:pfam03600 181 FRKLLPVRKEEEAELEELRKRAIKDKLLLAISALVLALVILGFLLLSVLALAGALLLLLTGVLDPEEALKAVDWSTLLFF 260
|
90 100 110 120 130 140 150
....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 51921291 91 LGSLIVAVAVERWKLHKRVALRMLLFVGtkPSRLMLGFMFVTAFLSMWISNTAATAMMIPIVEAMLQQMIAAN 163
Cdd:pfam03600 261 AGLFILVGALEKTGLADALADALGGLSG--LLVALALILWLSALLSAFISNVPTAALMAPIIVGMAPAAGLGD 331
|
|
| SLC13_permease |
cd01115 |
Permease SLC13 (solute carrier 13). The sodium/dicarboxylate cotransporter NaDC-1 has been ... |
11-166 |
1.16e-04 |
|
Permease SLC13 (solute carrier 13). The sodium/dicarboxylate cotransporter NaDC-1 has been shown to translocate Krebs cycle intermediates such as succinate, citrate, and alpha-ketoglutarate across plasma membranes rabbit, human, and rat kidney. It is related to renal and intestinal Na+/sulfate cotransporters and a few putative bacterial permeases. The SLC13-type proteins belong to the ArsB/NhaD superfamily of permeases that translocate sodium and various anions across biological membranes in all three kingdoms of life. A typical ArsB/NhaD permease is composed of 8-13 transmembrane helices.
Pssm-ID: 238535 [Multi-domain] Cd Length: 382 Bit Score: 44.50 E-value: 1.16e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 51921291 11 FKSFAILLFTPILMLPLVILIP-----DKFARCAYVIVIMAV-YWCTDVIPVAVTSLLPVLLFPLLKVLDSKQVCIQYMK 84
Cdd:cd01115 162 GQGFSFFEFTPIGLPLLIIGLLylwfiFRLAVLIITIVLLAAlAAITGLLPVSVAIAIGAIVLVFGGVLLTKEDYKSIDW 241
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 51921291 85 DTNMLFLGSLIVAVAVERWKLHKRVALRMLLFVGTKPSRLMLG-FMFVTAFLSMWISNTAATAMMIPIVEAMLQQMIAAN 163
Cdd:cd01115 242 GIIFLFAGGIPLGKALESSGAAALIAEALISLLGGLPPFAILLlLCLLTLVLTNFISNTATAVLLAPIALSIALSLGLPP 321
|
...
gi 51921291 164 TAV 166
Cdd:cd01115 322 EAL 324
|
|
| CitT |
COG0471 |
Di- and tricarboxylate antiporter [Carbohydrate transport and metabolism]; |
41-159 |
2.28e-03 |
|
Di- and tricarboxylate antiporter [Carbohydrate transport and metabolism];
Pssm-ID: 440239 [Multi-domain] Cd Length: 369 Bit Score: 40.52 E-value: 2.28e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 51921291 41 VIVIMAVYWCTD---VIPVAVTSLLPVLLFPLLKVLDSKQvcIQYMKDTNMLFL--GSLIVAVAVERWKLHKRVALRMLL 115
Cdd:COG0471 180 IFALTVLLWITGslhGIPIAVVALLGAVLLLLTGVLTWKD--AYKSIPWGVLLLfgGGLALGAALEKTGLAAWLADALLP 257
|
90 100 110 120
....*....|....*....|....*....|....*....|....*
gi 51921291 116 FVGTKPSRLML-GFMFVTAFLSMWISNTAATAMMIPIVEAMLQQM 159
Cdd:COG0471 258 LLGGLSPLLLLlLLALLTLLLTEFASNTATAALLLPIAISLAQAL 302
|
|
| |
