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Conserved domains on  [gi|56090598|ref|NP_001007735|]
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ethylmalonyl-CoA decarboxylase isoform 1 [Rattus norvegicus]

Protein Classification

enoyl-CoA hydratase/isomerase family protein( domain architecture ID 10787157)

enoyl-CoA hydratase/isomerase family protein similar to human ethylmalonyl-CoA decarboxylase that decarboxylates ethylmalonyl-CoA, a potentially toxic metabolite, to form butyryl-CoA

CATH:  3.90.226.10
Gene Ontology:  GO:0016829
PubMed:  12467702|22016388

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
CaiD COG1024
Enoyl-CoA hydratase/carnithine racemase [Lipid transport and metabolism]; Enoyl-CoA hydratase ...
 52-292 8.45e-61

Enoyl-CoA hydratase/carnithine racemase [Lipid transport and metabolism]; Enoyl-CoA hydratase/carnithine racemase is part of the Pathway/BioSystem: Fatty acid biosynthesis


:

Pssm-ID: 440647 [Multi-domain]  Cd Length: 249  Bit Score: 193.46  E-value: 8.45e-61
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 56090598  52 KQNGIGILTLNNSNKMNAFSGAMMLQLLERVIELENWTEGKGLIVHGAKNTFCSGSDLNAVKALSTPENGVALSMFMQNT 131
Cdd:COG1024   5 REGGVATITLNRPEKLNALSLEMLAELAAALDEAEADPDVRVVVLTGAGKAFCAGADLKELAAAADPEEARAFARGLQRL 84

                        90       100       110       120       130       140       150       160
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 56090598 132 LTRFMRLPLISVALVQGWAMGGGAELTTACDFRLMTEESVIRFVHKEMGIVPSWGGASRLVEIIGSRQALK-VLSGTFkL 210
Cdd:COG1024  85 FRALRRLPKPVIAAVNGAALGGGLELALACDLRIAAEDARFGLPEVRLGLIPGGGGTQRLPRLVGLARAKElLLTGRR-I 163

                       170       180       190       200       210       220       230       240
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 56090598 211 DSKEALRIGLADEVLqPSDEatALEQAQEWLEQFVSGPAQVIRGLKKSVCSGRELYLEEALQNERDVLETLWGGPANLEA 290
Cdd:COG1024 164 DAEEALELGLVNRVV-PDDE--LLAAALALAARLAAGPPLALAATKRALNAALEAPLDEALELEAEAFAELFASEDAREG 240


                ..
gi 56090598 291 IA 292
Cdd:COG1024 241 IA 242
 
Name Accession Description Interval E-value
CaiD COG1024
Enoyl-CoA hydratase/carnithine racemase [Lipid transport and metabolism]; Enoyl-CoA hydratase ...
 52-292 8.45e-61

Enoyl-CoA hydratase/carnithine racemase [Lipid transport and metabolism]; Enoyl-CoA hydratase/carnithine racemase is part of the Pathway/BioSystem: Fatty acid biosynthesis


Pssm-ID: 440647 [Multi-domain]  Cd Length: 249  Bit Score: 193.46  E-value: 8.45e-61
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 56090598  52 KQNGIGILTLNNSNKMNAFSGAMMLQLLERVIELENWTEGKGLIVHGAKNTFCSGSDLNAVKALSTPENGVALSMFMQNT 131
Cdd:COG1024   5 REGGVATITLNRPEKLNALSLEMLAELAAALDEAEADPDVRVVVLTGAGKAFCAGADLKELAAAADPEEARAFARGLQRL 84

                        90       100       110       120       130       140       150       160
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 56090598 132 LTRFMRLPLISVALVQGWAMGGGAELTTACDFRLMTEESVIRFVHKEMGIVPSWGGASRLVEIIGSRQALK-VLSGTFkL 210
Cdd:COG1024  85 FRALRRLPKPVIAAVNGAALGGGLELALACDLRIAAEDARFGLPEVRLGLIPGGGGTQRLPRLVGLARAKElLLTGRR-I 163

                       170       180       190       200       210       220       230       240
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 56090598 211 DSKEALRIGLADEVLqPSDEatALEQAQEWLEQFVSGPAQVIRGLKKSVCSGRELYLEEALQNERDVLETLWGGPANLEA 290
Cdd:COG1024 164 DAEEALELGLVNRVV-PDDE--LLAAALALAARLAAGPPLALAATKRALNAALEAPLDEALELEAEAFAELFASEDAREG 240


                ..
gi 56090598 291 IA 292
Cdd:COG1024 241 IA 242
crotonase-like cd06558
Crotonase/Enoyl-Coenzyme A (CoA) hydratase superfamily. This superfamily contains a diverse ...
 52-243 2.71e-54

Crotonase/Enoyl-Coenzyme A (CoA) hydratase superfamily. This superfamily contains a diverse set of enzymes including enoyl-CoA hydratase, napthoate synthase, methylmalonyl-CoA decarboxylase, 3-hydoxybutyryl-CoA dehydratase, and dienoyl-CoA isomerase. Many of these play important roles in fatty acid metabolism. In addition to a conserved structural core and the formation of trimers (or dimers of trimers), a common feature in this superfamily is the stabilization of an enolate anion intermediate derived from an acyl-CoA substrate. This is accomplished by two conserved backbone NH groups in active sites that form an oxyanion hole.


Pssm-ID: 119339 [Multi-domain]  Cd Length: 195  Bit Score: 175.06  E-value: 2.71e-54
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 56090598  52 KQNGIGILTLNNSNKMNAFSGAMMLQLLERVIELENWTEGKGLIVHGAKNTFCSGSDLNAVKALST-PENGVALSMFMQN 130
Cdd:cd06558   5 RDGGVATITLNRPEKRNALSLEMLDELAAALDEAEADPDVRVVVLTGAGKAFCAGADLKELAALSDaGEEARAFIRELQE 84

                        90       100       110       120       130       140       150       160
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 56090598 131 TLTRFMRLPLISVALVQGWAMGGGAELTTACDFRLMTEESVIRFVHKEMGIVPSWGGASRLVEIIGSRQALKVLSGTFKL 210
Cdd:cd06558  85 LLRALLRLPKPVIAAVNGAALGGGLELALACDIRIAAEDAKFGLPEVKLGLVPGGGGTQRLPRLVGPARARELLLTGRRI 164

                       170       180       190
                ....*....|....*....|....*....|...
gi 56090598 211 DSKEALRIGLADEVLqpsDEATALEQAQEWLEQ 243
Cdd:cd06558 165 SAEEALELGLVDEVV---PDEELLAAALELARR 194
ECH_1 pfam00378
Enoyl-CoA hydratase/isomerase; This family contains a diverse set of enzymes including: ...
 52-279 2.98e-30

Enoyl-CoA hydratase/isomerase; This family contains a diverse set of enzymes including: enoyl-CoA hydratase, napthoate synthase, carnitate racemase, 3-hydroxybutyryl-CoA dehydratase and dodecanoyl-CoA delta-isomerase.


Pssm-ID: 395302 [Multi-domain]  Cd Length: 251  Bit Score: 114.38  E-value: 2.98e-30
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 56090598    52 KQNGIGILTLNNSNKMNAFSGAMMLQLLERVIELENWTEGKGLIVHGAKNTFCSGSDLNAVKALSTPENGVALSMFmQNT 131
Cdd:pfam00378   2 INAGVAVITLNRPEAVNALSAELITELIQALEKLRTDPSVRAVVLTGGDKAFCAGADLKEMYGEGPAHQALYRENV-LDL 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 56090598   132 LTRFMRLPLISVALVQGWAMGGGAELTTACDFRLMTEESVIRFVHKEMGIVPSWGGASRLVEIIGSRQALKVLSGTFKLD 211
Cdd:pfam00378  81 WTLLYTCPKPVIAAVNGYAIGGGCELALACDIIIAADNASFGLNETKLGIIPGAGGTDRLPRIIGHSKAMEMLLLGRRIS 160

                         170       180       190       200       210       220
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 56090598   212 SKEALRIGLADEVLQpsdEATALEQAQEWLEQFVSGPAQVIRGLKKSVCSGRELYLEEALQNERDVLE 279
Cdd:pfam00378 161 AQEALKWGLVDKVVP---EDQLLDEARELAEKLAEKSPAALAQLKKALNAKLEDALPTQLEAEARLFY 225
PRK06190 PRK06190
enoyl-CoA hydratase; Provisional
 43-276 2.01e-27

enoyl-CoA hydratase; Provisional


Pssm-ID: 235733  Cd Length: 258  Bit Score: 106.98  E-value: 2.01e-27
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 56090598   43 PGGSIDLQKKQNGIGILTLNNSNKMNAFSGAMMLQLLERVIELENWTEGKGLIVHGAKNTFCSGSDLnavKALSTPENGV 122
Cdd:PRK06190   1 MTEPILLVETHDRVRTLTLNRPEARNALSAALRRALFAALAEADADDDVDVVVLTGADPAFCAGLDL---KELGGDGSAY 77

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 56090598  123 ALSMFMQNTLTRF--MRLPLISValVQGWAMGGGAELTTACDFRLMTEESVIRFVHKEMGIVPSWGGASRLVEIIGSRQA 200
Cdd:PRK06190  78 GAQDALPNPSPAWpaMRKPVIGA--INGAAVTGGLELALACDILIASERARFADTHARVGILPGWGLSVRLPQKVGIGRA 155

                        170       180       190       200       210       220       230
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 56090598  201 LKV-LSGTFkLDSKEALRIGLADEVLqPSDE--ATALEQAQewleQFVSGPAQVIRGLKKSVCSGRELYLEEALQNERD 276
Cdd:PRK06190 156 RRMsLTGDF-LDAADALRAGLVTEVV-PHDEllPRARRLAA----SIAGNNPAAVRALKASYDDGAAAQTGDALALEAE 228
fa_ox_alpha_mit TIGR02441
fatty acid oxidation complex, alpha subunit, mitochondrial; Members represent alpha subunit of ...
 51-250 3.33e-16

fatty acid oxidation complex, alpha subunit, mitochondrial; Members represent alpha subunit of mitochondrial multifunctional fatty acid degradation enzyme complex. Subunit activities include: enoyl-CoA hydratase (EC 4.2.1.17) _ 3-hydroxyacyl-CoA dehydrogenase (EC 1.1.1.35). Some characterization in human (SP:P40939), pig (SP:Q29554), and rat (SP:Q64428). The beta subunit has activity: acetyl-CoA C-acyltransferase (EC 2.3.1.16).


Pssm-ID: 131494 [Multi-domain]  Cd Length: 737  Bit Score: 78.73  E-value: 3.33e-16
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 56090598    51 KKQNGIGILTLNNSN-KMNAFSGAMMLQLLERVIELENWTEGKGLIVHGAK-NTFCSGSDLNAVKALSTPENGVALSMFM 128
Cdd:TIGR02441  18 EVKGDVAVVKIDSPNsKVNTLSKELFAEFKEVMNELWTNEAIKSAVLISGKpGSFVAGADIQMIAACKTAQEVTQLSQEG 97

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 56090598   129 QNTLTRFMRLPLISVALVQGWAMGGGAELTTACDFRLMTEESVIRFVHKE--MGIVPSWGGASRLVEIIGSRQALKVLSG 206
Cdd:TIGR02441  98 QEMFERIEKSQKPIVAAISGSCLGGGLELALACHYRIATKDRKTLLGLPEvmLGLLPGAGGTQRLPKLTGVPAALDMMLT 177

                         170       180       190       200
                  ....*....|....*....|....*....|....*....|....*.
gi 56090598   207 TFKLDSKEALRIGLADEVLQPSDEAT--ALEQAQEWLEQFVSGPAQ 250
Cdd:TIGR02441 178 GKKIRADRAKKMGIVDQLVDPLGPGLkpAEENTIEYLEEVAVKFAQ 223
 
Name Accession Description Interval E-value
CaiD COG1024
Enoyl-CoA hydratase/carnithine racemase [Lipid transport and metabolism]; Enoyl-CoA hydratase ...
 52-292 8.45e-61

Enoyl-CoA hydratase/carnithine racemase [Lipid transport and metabolism]; Enoyl-CoA hydratase/carnithine racemase is part of the Pathway/BioSystem: Fatty acid biosynthesis


Pssm-ID: 440647 [Multi-domain]  Cd Length: 249  Bit Score: 193.46  E-value: 8.45e-61
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 56090598  52 KQNGIGILTLNNSNKMNAFSGAMMLQLLERVIELENWTEGKGLIVHGAKNTFCSGSDLNAVKALSTPENGVALSMFMQNT 131
Cdd:COG1024   5 REGGVATITLNRPEKLNALSLEMLAELAAALDEAEADPDVRVVVLTGAGKAFCAGADLKELAAAADPEEARAFARGLQRL 84

                        90       100       110       120       130       140       150       160
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 56090598 132 LTRFMRLPLISVALVQGWAMGGGAELTTACDFRLMTEESVIRFVHKEMGIVPSWGGASRLVEIIGSRQALK-VLSGTFkL 210
Cdd:COG1024  85 FRALRRLPKPVIAAVNGAALGGGLELALACDLRIAAEDARFGLPEVRLGLIPGGGGTQRLPRLVGLARAKElLLTGRR-I 163

                       170       180       190       200       210       220       230       240
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 56090598 211 DSKEALRIGLADEVLqPSDEatALEQAQEWLEQFVSGPAQVIRGLKKSVCSGRELYLEEALQNERDVLETLWGGPANLEA 290
Cdd:COG1024 164 DAEEALELGLVNRVV-PDDE--LLAAALALAARLAAGPPLALAATKRALNAALEAPLDEALELEAEAFAELFASEDAREG 240


                ..
gi 56090598 291 IA 292
Cdd:COG1024 241 IA 242
crotonase-like cd06558
Crotonase/Enoyl-Coenzyme A (CoA) hydratase superfamily. This superfamily contains a diverse ...
 52-243 2.71e-54

Crotonase/Enoyl-Coenzyme A (CoA) hydratase superfamily. This superfamily contains a diverse set of enzymes including enoyl-CoA hydratase, napthoate synthase, methylmalonyl-CoA decarboxylase, 3-hydoxybutyryl-CoA dehydratase, and dienoyl-CoA isomerase. Many of these play important roles in fatty acid metabolism. In addition to a conserved structural core and the formation of trimers (or dimers of trimers), a common feature in this superfamily is the stabilization of an enolate anion intermediate derived from an acyl-CoA substrate. This is accomplished by two conserved backbone NH groups in active sites that form an oxyanion hole.


Pssm-ID: 119339 [Multi-domain]  Cd Length: 195  Bit Score: 175.06  E-value: 2.71e-54
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 56090598  52 KQNGIGILTLNNSNKMNAFSGAMMLQLLERVIELENWTEGKGLIVHGAKNTFCSGSDLNAVKALST-PENGVALSMFMQN 130
Cdd:cd06558   5 RDGGVATITLNRPEKRNALSLEMLDELAAALDEAEADPDVRVVVLTGAGKAFCAGADLKELAALSDaGEEARAFIRELQE 84

                        90       100       110       120       130       140       150       160
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 56090598 131 TLTRFMRLPLISVALVQGWAMGGGAELTTACDFRLMTEESVIRFVHKEMGIVPSWGGASRLVEIIGSRQALKVLSGTFKL 210
Cdd:cd06558  85 LLRALLRLPKPVIAAVNGAALGGGLELALACDIRIAAEDAKFGLPEVKLGLVPGGGGTQRLPRLVGPARARELLLTGRRI 164

                       170       180       190
                ....*....|....*....|....*....|...
gi 56090598 211 DSKEALRIGLADEVLqpsDEATALEQAQEWLEQ 243
Cdd:cd06558 165 SAEEALELGLVDEVV---PDEELLAAALELARR 194
ECH_1 pfam00378
Enoyl-CoA hydratase/isomerase; This family contains a diverse set of enzymes including: ...
 52-279 2.98e-30

Enoyl-CoA hydratase/isomerase; This family contains a diverse set of enzymes including: enoyl-CoA hydratase, napthoate synthase, carnitate racemase, 3-hydroxybutyryl-CoA dehydratase and dodecanoyl-CoA delta-isomerase.


Pssm-ID: 395302 [Multi-domain]  Cd Length: 251  Bit Score: 114.38  E-value: 2.98e-30
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 56090598    52 KQNGIGILTLNNSNKMNAFSGAMMLQLLERVIELENWTEGKGLIVHGAKNTFCSGSDLNAVKALSTPENGVALSMFmQNT 131
Cdd:pfam00378   2 INAGVAVITLNRPEAVNALSAELITELIQALEKLRTDPSVRAVVLTGGDKAFCAGADLKEMYGEGPAHQALYRENV-LDL 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 56090598   132 LTRFMRLPLISVALVQGWAMGGGAELTTACDFRLMTEESVIRFVHKEMGIVPSWGGASRLVEIIGSRQALKVLSGTFKLD 211
Cdd:pfam00378  81 WTLLYTCPKPVIAAVNGYAIGGGCELALACDIIIAADNASFGLNETKLGIIPGAGGTDRLPRIIGHSKAMEMLLLGRRIS 160

                         170       180       190       200       210       220
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 56090598   212 SKEALRIGLADEVLQpsdEATALEQAQEWLEQFVSGPAQVIRGLKKSVCSGRELYLEEALQNERDVLE 279
Cdd:pfam00378 161 AQEALKWGLVDKVVP---EDQLLDEARELAEKLAEKSPAALAQLKKALNAKLEDALPTQLEAEARLFY 225
PRK06190 PRK06190
enoyl-CoA hydratase; Provisional
 43-276 2.01e-27

enoyl-CoA hydratase; Provisional


Pssm-ID: 235733  Cd Length: 258  Bit Score: 106.98  E-value: 2.01e-27
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 56090598   43 PGGSIDLQKKQNGIGILTLNNSNKMNAFSGAMMLQLLERVIELENWTEGKGLIVHGAKNTFCSGSDLnavKALSTPENGV 122
Cdd:PRK06190   1 MTEPILLVETHDRVRTLTLNRPEARNALSAALRRALFAALAEADADDDVDVVVLTGADPAFCAGLDL---KELGGDGSAY 77

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 56090598  123 ALSMFMQNTLTRF--MRLPLISValVQGWAMGGGAELTTACDFRLMTEESVIRFVHKEMGIVPSWGGASRLVEIIGSRQA 200
Cdd:PRK06190  78 GAQDALPNPSPAWpaMRKPVIGA--INGAAVTGGLELALACDILIASERARFADTHARVGILPGWGLSVRLPQKVGIGRA 155

                        170       180       190       200       210       220       230
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 56090598  201 LKV-LSGTFkLDSKEALRIGLADEVLqPSDE--ATALEQAQewleQFVSGPAQVIRGLKKSVCSGRELYLEEALQNERD 276
Cdd:PRK06190 156 RRMsLTGDF-LDAADALRAGLVTEVV-PHDEllPRARRLAA----SIAGNNPAAVRALKASYDDGAAAQTGDALALEAE 228
PRK06144 PRK06144
enoyl-CoA hydratase; Provisional
 40-238 1.73e-26

enoyl-CoA hydratase; Provisional


Pssm-ID: 180424 [Multi-domain]  Cd Length: 262  Bit Score: 104.69  E-value: 1.73e-26
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 56090598   40 EQFPGGSIDLQ-KKQNGIGILTLNNSNKMNAFSGAMMLQLLERVIELENWTEGKGLIVHGA-KNTFCSGSDLNAVKALST 117
Cdd:PRK06144   1 MAMTTSTDELLlEVRGGIARITFNRPAARNAMTWAMYEGLAEICEAIAADPSIRAVVLRGAgDKAFVAGTDIAQFRAFST 80

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 56090598  118 PENGVALSMFMQNTLTRFMRLPLISVALVQGWAMGGGAELTTACDFRLMTEESviRF---VHKEMGIVPSWGGASRLVEI 194
Cdd:PRK06144  81 AEDAVAYERRIDRVLGALEQLRVPTIAAIAGACVGGGAAIAAACDLRIATPSA--RFgfpIARTLGNCLSMSNLARLVAL 158

                        170       180       190       200
                 ....*....|....*....|....*....|....*....|....*
gi 56090598  195 IGSRQALKVLSGTFKLDSKEALRIGLADEVLQPSD-EATALEQAQ 238
Cdd:PRK06144 159 LGAARVKDMLFTARLLEAEEALAAGLVNEVVEDAAlDARADALAE 203
PRK07657 PRK07657
enoyl-CoA hydratase; Provisional
 53-279 2.17e-26

enoyl-CoA hydratase; Provisional


Pssm-ID: 181069 [Multi-domain]  Cd Length: 260  Bit Score: 104.43  E-value: 2.17e-26
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 56090598   53 QNGIGILTLNNSNKMNAFSGAMMLQLLERVIELENWTEGKGLIVHGAKN-TFCSGSDLNAVKALSTPENGVALSMfMQNT 131
Cdd:PRK07657  11 TPHVVKITLNRPRAANALSLALLEELQNILTQINEEANVRVVILTGAGEkAFCAGADLKERAGMNEEQVRHAVSL-IRTT 89

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 56090598  132 LTRFMRLPLISVALVQGWAMGGGAELTTACDFRLMTEESVIRFVHKEMGIVPSWGGASRLVEIIGSRQALKVLSGTFKLD 211
Cdd:PRK07657  90 MEMVEQLPQPVIAAINGIALGGGLELALACDFRIAAESASLGLTETTLAIIPGAGGTQRLPRLIGVGRAKELIYTGRRIS 169

                        170       180       190       200       210       220
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 56090598  212 SKEALRIGLADEVLQPSDeatALEQAQEWLEQFVS-GPAQViRGLKKSVCSGRELYLEEALQNERDVLE 279
Cdd:PRK07657 170 AQEAKEIGLVEFVVPAHL---LEEKAIEIAEKIASnGPIAV-RQAKEAISNGIQVDLHTGLQIEKQAYE 234
PRK06688 PRK06688
enoyl-CoA hydratase; Provisional
 49-292 7.97e-26

enoyl-CoA hydratase; Provisional


Pssm-ID: 235852 [Multi-domain]  Cd Length: 259  Bit Score: 102.64  E-value: 7.97e-26
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 56090598   49 LQKKQNGIGILTLNNSNKMNAFSGAMMLQLLERVIELENWTEGKGLIVHGAKNTFCSGSDLNAVKALSTPENGVALSMFm 128
Cdd:PRK06688   8 LVELEDGVLTITINRPDKKNALTAAMYQALADALEAAATDPAVRVVVLTGAGRAFSAGGDIKDFPKAPPKPPDELAPVN- 86

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 56090598  129 qntltRFMR----LPLISVALVQGWAMGGGAELTTACDFRLMTEESVIRFVHKEMGIVPSWGGASRLVEIIGS-RQALKV 203
Cdd:PRK06688  87 -----RFLRaiaaLPKPVVAAVNGPAVGVGVSLALACDLVYASESAKFSLPFAKLGLCPDAGGSALLPRLIGRaRAAEML 161

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 56090598  204 LSGTfKLDSKEALRIGLADEVLqPSDEATALEQAQewLEQFVSGPAQVIRGLKKSVCSGRELYLEEALQNERDVLETLWG 283
Cdd:PRK06688 162 LLGE-PLSAEEALRIGLVNRVV-PAAELDAEADAQ--AAKLAAGPASALRYTKRAINAATLTELEEALAREAAGFGRLLR 237


                 ....*....
gi 56090598  284 GPANLEAIA 292
Cdd:PRK06688 238 TPDFREGAT 246
PRK06494 PRK06494
enoyl-CoA hydratase; Provisional
 52-276 7.23e-24

enoyl-CoA hydratase; Provisional


Pssm-ID: 180591 [Multi-domain]  Cd Length: 259  Bit Score: 97.42  E-value: 7.23e-24
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 56090598   52 KQNGIGILTLNNSNKMNAFSGAMMLQLLERVIELENWTEGKGLIVHGA-KNTFCSGSDLN---AVKALSTPENGVAlsmf 127
Cdd:PRK06494  10 RKGHVTIVTLNRPEVMNALHLDAHFELEEVFDDFAADPEQWVAIVTGAgDKAFSAGNDLKeqaAGGKRGWPESGFG---- 85

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 56090598  128 mqnTLT-RF-MRLPLIsvALVQGWAMGGGAELTTACDFRLMTEESVIRFVHKEMGIVPSWGGASRLVEIIGSRQALKVLS 205
Cdd:PRK06494  86 ---GLTsRFdLDKPII--AAVNGVAMGGGFELALACDLIVAAENATFALPEPRVGLAALAGGLHRLPRQIGLKRAMGMIL 160

                        170       180       190       200       210       220       230
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 56090598  206 GTFKLDSKEALRIGLADEVLQPSDeatALEQAQEWLEQFVSGPAQVIRGLKKSVCSGRELYLEEALQNERD 276
Cdd:PRK06494 161 TGRRVTAREGLELGFVNEVVPAGE---LLAAAERWADDILACSPLSIRASKQAVYRGLEVSLEEAITAQRD 228
PLN02888 PLN02888
enoyl-CoA hydratase
 47-276 7.75e-24

enoyl-CoA hydratase


Pssm-ID: 215480  Cd Length: 265  Bit Score: 97.52  E-value: 7.75e-24
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 56090598   47 IDLQKKQNGIGILTLNNSNKMNAFSGAMMLQLLERVIELENWTEGKGLIVHGAKNTFCSGSDLNA--------VKALSTp 118
Cdd:PLN02888  11 ILVPKSRNGIATITINRPKALNALTRPMMVELAAAFKRLDEDDSVKVIILTGSGRAFCSGVDLTAaeevfkgdVKDVET- 89

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 56090598  119 eNGVALsmfMQNtltrfMRLPLISValVQGWAMGGGAELTTACDFRLMTEESVIRFVHKEMGIVPSWGGASRLVEIIGSR 198
Cdd:PLN02888  90 -DPVAQ---MER-----CRKPIIGA--INGFAITAGFEIALACDILVASRGAKFIDTHAKFGIFPSWGLSQKLSRIIGAN 158

                        170       180       190       200       210       220       230
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 56090598  199 QALKVLSGTFKLDSKEALRIGLADEVLQPSDeatALEQAQEWLEQFVSGPAQVIRGLKKSVCSGRELYLEEALQNERD 276
Cdd:PLN02888 159 RAREVSLTAMPLTAETAERWGLVNHVVEESE---LLKKAREVAEAIIKNNQGMVLRYKSVINDGLKLDLGHALQLEKE 233
PRK07658 PRK07658
enoyl-CoA hydratase; Provisional
 51-274 4.21e-23

enoyl-CoA hydratase; Provisional


Pssm-ID: 181070 [Multi-domain]  Cd Length: 257  Bit Score: 95.47  E-value: 4.21e-23
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 56090598   51 KKQNGIGILTLNNSnKMNAFSGAMMLQLLERVIELENWTEGKGLIVHGAKNTFCSGSDLNAVKALSTPENGVALSMFMQN 130
Cdd:PRK07658   7 RVEDHVAVITLNHP-PANALSSQVLHELSELLDQVEKDDNVRVVVIHGEGRFFSAGADIKEFTSVTEAEQATELAQLGQV 85

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 56090598  131 TLTRFMRLPLISVALVQGWAMGGGAELTTACDFRLMTEESVIRFVHKEMGIVPSWGGASRLVEIIGSRQALKVLSGTFKL 210
Cdd:PRK07658  86 TFERVEKFSKPVIAAIHGAALGGGLELAMSCHIRFATESAKLGLPELNLGLIPGFAGTQRLPRYVGKAKALEMMLTSEPI 165

                        170       180       190       200       210       220
                 ....*....|....*....|....*....|....*....|....*....|....*....|....
gi 56090598  211 DSKEALRIGLADEVLqpsDEATALEQAQEWLEQFVSGPAQVIRGLKKSVCSGRELYLEEALQNE 274
Cdd:PRK07658 166 TGAEALKWGLVNGVF---PEETLLDDAKKLAKKIAGKSPATTRAVLELLQTTKSSSYYEGVKRE 226
PRK08260 PRK08260
enoyl-CoA hydratase; Provisional
 53-243 8.97e-23

enoyl-CoA hydratase; Provisional


Pssm-ID: 236206 [Multi-domain]  Cd Length: 296  Bit Score: 95.46  E-value: 8.97e-23
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 56090598   53 QNGIGILTLNNSNKMNAFSGAMMLQLLERVIELENWTEGKGLIVHGAKNTFCSGSDLNAVKALSTPENGVALSMFMQN-- 130
Cdd:PRK08260  11 ADGIATITLNRPDKLNAFTVTMARELIEAFDAADADDAVRAVIVTGAGRAFCAGADLSAGGNTFDLDAPRTPVEADEEdr 90

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 56090598  131 ---------------TLTRF-MRLPLIsvALVQGWAMGGGAELTTACDFRLMTEESVIRFVHKEMGIVP----SWggasR 190
Cdd:PRK08260  91 adpsddgvrdgggrvTLRIFdSLKPVI--AAVNGPAVGVGATMTLAMDIRLASTAARFGFVFGRRGIVPeaasSW----F 164

                        170       180       190       200       210
                 ....*....|....*....|....*....|....*....|....*....|....*
gi 56090598  191 LVEIIGSRQALK-VLSGTFkLDSKEALRIGLADEVLQPSD-EATALEQAQEWLEQ 243
Cdd:PRK08260 165 LPRLVGLQTALEwVYSGRV-FDAQEALDGGLVRSVHPPDElLPAARALAREIADN 218
PRK05809 PRK05809
short-chain-enoyl-CoA hydratase;
51-277 2.18e-22

short-chain-enoyl-CoA hydratase;


Pssm-ID: 180270 [Multi-domain]  Cd Length: 260  Bit Score: 93.66  E-value: 2.18e-22
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 56090598   51 KKQNGIGILTLNNSNKMNAFSGAMMLQLLERVIELENWTEGKGLIVHGA-KNTFCSGSDLNAVKALsTPENGVALSMFMQ 129
Cdd:PRK05809   9 EKEGHIAVVTINRPKALNALNSETLKELDTVLDDIENDDNVYAVILTGAgEKAFVAGADISEMKDL-NEEEGRKFGLLGN 87

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 56090598  130 NTLTRFMRLPLISVALVQGWAMGGGAELTTACDFRLMTEESviRFVHKE--MGIVPSWGGASRLVEIIGSRQALKVLSGT 207
Cdd:PRK05809  88 KVFRKLENLDKPVIAAINGFALGGGCELSMACDIRIASEKA--KFGQPEvgLGITPGFGGTQRLARIVGPGKAKELIYTG 165

                        170       180       190       200       210       220       230
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 56090598  208 FKLDSKEALRIGLADEVLQPSDeatALEQAQEWLEQFVSGPAQVIRGLKKSVCSGRELYLEEALQNERDV 277
Cdd:PRK05809 166 DMINAEEALRIGLVNKVVEPEK---LMEEAKALANKIAANAPIAVKLCKDAINRGMQVDIDTAVAIEAED 232
PLN02600 PLN02600
enoyl-CoA hydratase
 54-292 3.74e-22

enoyl-CoA hydratase


Pssm-ID: 178210 [Multi-domain]  Cd Length: 251  Bit Score: 92.94  E-value: 3.74e-22
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 56090598   54 NGIGILTLNNSNKMNAFsGAMMLQLLERVIE-LENWTEGKGLIVHGA-KNTFCSGSDLNAVKALSTPENGVALSMfMQNT 131
Cdd:PLN02600   3 SGIVELRLDRPEAKNAI-GKEMLRGLRSAFEkIQADASARVVMLRSSvPGVFCAGADLKERRKMSPSEVQKFVNS-LRST 80

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 56090598  132 LTRFMRLPLISVALVQGWAMGGGAELTTACDFRLMTEESVIRFVHKEMGIVPSWGGASRLVEIIGSRQALKVLSGTFKLD 211
Cdd:PLN02600  81 FSSLEALSIPTIAVVEGAALGGGLELALSCDLRICGEEAVFGLPETGLAIIPGAGGTQRLPRLVGRSRAKELIFTGRRIG 160

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 56090598  212 SKEALRIGLAdEVLQPSDEA--TALEQAQEWLEQfvsGPAqVIRGLKKSVCSGRELYLEEALQNERDVLETLWGGPANLE 289
Cdd:PLN02600 161 AREAASMGLV-NYCVPAGEAyeKALELAQEINQK---GPL-AIKMAKKAINEGSEVDMASGLEIEEECYEQVLKTKDRLE 235


                 ...
gi 56090598  290 AIA 292
Cdd:PLN02600 236 GLA 238
fadB PRK11730
fatty acid oxidation complex subunit alpha FadB;
42-258 1.28e-21

fatty acid oxidation complex subunit alpha FadB;


Pssm-ID: 183293 [Multi-domain]  Cd Length: 715  Bit Score: 94.93  E-value: 1.28e-21
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 56090598   42 FPGGSIDLQKKQNGIGILTLNNSNKMNAFSGAMMLQLLERVIELENWTEGKGLIVHGAKNTFCSGSDLNAVKAL-STPEN 120
Cdd:PRK11730   3 YQGKTLQVDWLEDGIAELVFDAPGSVNKLDRATLASLGEALDALEAQSDLKGLLLTSAKDAFIVGADITEFLSLfAAPEE 82

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 56090598  121 GVALSM-FMQNTLTRFMRLPLISVALVQGWAMGGGAELTTACDFRLMTEESVIRFVHKEMGIVPSWGGASRLVEIIGSRQ 199
Cdd:PRK11730  83 ELSQWLhFANSIFNRLEDLPVPTVAAINGYALGGGCECVLATDYRVASPDARIGLPETKLGIMPGFGGTVRLPRLIGADN 162

                        170       180       190       200       210       220
                 ....*....|....*....|....*....|....*....|....*....|....*....|.
gi 56090598  200 ALKVLSGTFKLDSKEALRIGLADEVLQPsdeATALEQAQEWLEQFVSGPA--QVIRGLKKS 258
Cdd:PRK11730 163 ALEWIAAGKDVRAEDALKVGAVDAVVAP---EKLQEAALALLKQAIAGKLdwKARRQPKLE 220
PRK05869 PRK05869
enoyl-CoA hydratase; Validated
 52-259 5.33e-21

enoyl-CoA hydratase; Validated


Pssm-ID: 235632 [Multi-domain]  Cd Length: 222  Bit Score: 89.13  E-value: 5.33e-21
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 56090598   52 KQNGIGILTLNNSnKMNAFSGAMMLQLLERVIELENWTEGKGLIVHGAKNTFCSGSDLNAVKALSTPENGVAlSMFMQNT 131
Cdd:PRK05869  14 QDAGLATLLLSRP-PTNALTRQVYREIVAAANELGRRDDVAAVILYGGHEIFSAGDDMPELRTLSAQEADTA-ARVRQQA 91

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 56090598  132 LTRFMRLPLISVALVQGWAMGGGAELTTACDFRLMTEEsvIRFVHKEM--GIVPSWGGASRLVEIIGSRQALK-VLSGTF 208
Cdd:PRK05869  92 VDAVAAIPKPTVAAITGYALGAGLTLALAADWRVSGDN--VKFGATEIlaGLAPSGDGMARLTRAAGPSRAKElVFSGRF 169

                        170       180       190       200       210
                 ....*....|....*....|....*....|....*....|....*....|.
gi 56090598  209 kLDSKEALRIGLADEVLQPSDeatALEQAQEWLEQFVSGPAQVIRGLKKSV 259
Cdd:PRK05869 170 -FDAEEALALGLIDEMVAPDD---VYDAAAAWARRFLDGPPHALAAAKAGI 216
PRK08259 PRK08259
crotonase/enoyl-CoA hydratase family protein;
52-274 6.84e-21

crotonase/enoyl-CoA hydratase family protein;


Pssm-ID: 236205  Cd Length: 254  Bit Score: 89.19  E-value: 6.84e-21
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 56090598   52 KQNGIGILTLNNSNKMNAFSGAMMLQLLERVIELENWTEGKGLIVHGAKNTFCSGSDLnavKALSTPE-NGVALS----M 126
Cdd:PRK08259   9 RNGPVTTVILNRPEVRNAVDGPTAAALADAFRAFDADDAASVAVLWGAGGTFCAGADL---KAVGTGRgNRLHPSgdgpM 85

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 56090598  127 fmqnTLTRfMRL--PLIsvALVQGWAMGGGAELTTACDFRLMTEESVirfvhkeMGI------VPSW-GGASRLVEIIGS 197
Cdd:PRK08259  86 ----GPSR-MRLskPVI--AAVSGYAVAGGLELALWCDLRVAEEDAV-------FGVfcrrwgVPLIdGGTVRLPRLIGH 151

                        170       180       190       200       210       220       230
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 56090598  198 RQALK-VLSGTfKLDSKEALRIGLADEVLQPsdeATALEQAQEWLEQFVSGPAQVIRGLKKSVCSGRELYLEEALQNE 274
Cdd:PRK08259 152 SRAMDlILTGR-PVDADEALAIGLANRVVPK---GQARAAAEELAAELAAFPQTCLRADRLSALEQWGLPEEAALANE 225
fadJ PRK11154
fatty acid oxidation complex subunit alpha FadJ;
49-228 1.29e-20

fatty acid oxidation complex subunit alpha FadJ;


Pssm-ID: 236864 [Multi-domain]  Cd Length: 708  Bit Score: 91.88  E-value: 1.29e-20
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 56090598   49 LQKKQNGIGILTLNNSN-KMNAFSGAMMLQLLERVIELENWTEGKGLIVHGAK-NTFCSGSDLNAVKALSTPENGVALSM 126
Cdd:PRK11154   9 LNVREDNIAVITIDVPGeKMNTLKAEFAEQVRAILKQLREDKELKGVVFISGKpDNFIAGADINMLAACKTAQEAEALAR 88

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 56090598  127 FMQNTLTRFMRLPLISVALVQGWAMGGGAELTTACDFRLMTEESVIRFVHKE--MGIVPSWGGASRLVEIIGSRQALK-V 203
Cdd:PRK11154  89 QGQQLFAEIEALPIPVVAAIHGACLGGGLELALACHYRVCTDDPKTVLGLPEvqLGLLPGSGGTQRLPRLIGVSTALDmI 168

                        170       180
                 ....*....|....*....|....*
gi 56090598  204 LSGTfKLDSKEALRIGLADEVLQPS 228
Cdd:PRK11154 169 LTGK-QLRAKQALKLGLVDDVVPHS 192
PRK05870 PRK05870
enoyl-CoA hydratase; Provisional
 54-259 1.54e-20

enoyl-CoA hydratase; Provisional


Pssm-ID: 180298  Cd Length: 249  Bit Score: 88.24  E-value: 1.54e-20
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 56090598   54 NGIGILTLNNSNKMNAFSGAMMLQLLERVIELENWTEGKGLIVHGAKNTFCSGSDLNAVKALSTPENGVALSMFMQNTLt 133
Cdd:PRK05870  11 DGVALITVNDPDRRNAVTAEMSAQLRAAVAAAEADPDVHALVVTGAGKAFCAGADLTALGAAPGRPAEDGLRRIYDGFL- 89

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 56090598  134 RFMRLPLISVALVQGWAMGGGAELTTACDFRLMTEES--VIRFVhkEMGIVPSWGGASRLVEIIGSRQALKVLSGTFKLD 211
Cdd:PRK05870  90 AVASCPLPTIAAVNGAAVGAGLNLALAADVRIAGPKAlfDARFQ--KLGLHPGGGATWMLQRAVGPQVARAALLFGMRFD 167

                        170       180       190       200       210
                 ....*....|....*....|....*....|....*....|....*....|
gi 56090598  212 SKEALRIGLADEVlqpSDE--ATALEQAQEWleqfVSGPAQVIRGLKKSV 259
Cdd:PRK05870 168 AEAAVRHGLALMV---ADDpvAAALELAAGP----AAAPRELVLATKASM 210
PRK06127 PRK06127
enoyl-CoA hydratase; Provisional
 42-234 2.64e-20

enoyl-CoA hydratase; Provisional


Pssm-ID: 235705  Cd Length: 269  Bit Score: 88.22  E-value: 2.64e-20
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 56090598   42 FPGGSIdLQKKQNGIGILTLNNSNKMNAFSGAMMLQLLERVIELENWTEGKGLIVHGA-KNTFCSGSDLNAVKALSTPEN 120
Cdd:PRK06127   8 SPTGKL-LAEKTGGLGRITFNNPARHNAMSLDMWEALPQALAAAEDDDAIRVVVLTGAgEKAFVSGADISQFEESRSDAE 86

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 56090598  121 GVAlsMFMQNTLTRFMRL---PLISVALVQGWAMGGGAELTTACDFRLMTEESVIRFVHKEMGIVPSWGGASRLVEIIGS 197
Cdd:PRK06127  87 AVA--AYEQAVEAAQAALadyAKPTIACIRGYCIGGGMGIALACDIRIAAEDSRFGIPAARLGLGYGYDGVKNLVDLVGP 164

                        170       180       190
                 ....*....|....*....|....*....|....*..
gi 56090598  198 RQALKVLSGTFKLDSKEALRIGLADEVLQPSDEATAL 234
Cdd:PRK06127 165 SAAKDLFYTARRFDAAEALRIGLVHRVTAADDLETAL 201
PRK08138 PRK08138
enoyl-CoA hydratase; Provisional
 49-275 1.17e-19

enoyl-CoA hydratase; Provisional


Pssm-ID: 236162 [Multi-domain]  Cd Length: 261  Bit Score: 86.26  E-value: 1.17e-19
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 56090598   49 LQKKQNGIGILTLNNSNKMNAFSGAMMLQLLERVIELENWTEGKGLIVHGAKNTFCSGSDLNAVKALStpengvALSMFM 128
Cdd:PRK08138  11 LERPADGVALLRLNRPEARNALNMEVRQQLAEHFTELSEDPDIRAIVLTGGEKVFAAGADIKEFATAG------AIEMYL 84

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 56090598  129 QNT------LTRfMRLPLIsvALVQGWAMGGGAELTTACDFRLMTEESviRFVHKE--MGIVPSWGGASRLVEIIGSRQA 200
Cdd:PRK08138  85 RHTeryweaIAQ-CPKPVI--AAVNGYALGGGCELAMHADIIVAGESA--SFGQPEikVGLMPGAGGTQRLVRAVGKFKA 159

                        170       180       190       200       210       220       230
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 56090598  201 LKVLSGTFKLDSKEALRIGLADEVlqpSDEATALEQAQEWLEQFVSGPAQVIRGLKKSVCSGRELYLEEALQNER 275
Cdd:PRK08138 160 MRMALTGCMVPAPEALAIGLVSEV---VEDEQTLPRALELAREIARMPPLALAQIKEVVLAGADAPLDAALALER 231
PRK09674 PRK09674
enoyl-CoA hydratase-isomerase; Provisional
 46-292 4.95e-19

enoyl-CoA hydratase-isomerase; Provisional


Pssm-ID: 182026 [Multi-domain]  Cd Length: 255  Bit Score: 84.43  E-value: 4.95e-19
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 56090598   46 SIDLQKKQNGIGILTLNNSNKMNAFSGAMMLQLLERVIELENWTEGKGLIVHGAKNTFCSGSDLN--AVKALSTPENGVA 123
Cdd:PRK09674   2 SELLVSRQQRVLLLTLNRPEARNALNNALLTQLVNELEAAATDTSIGVCVITGNARFFAAGADLNemAEKDLAATLNDPR 81

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 56090598  124 LSMFMQntLTRFMRlPLIsvALVQGWAMGGGAELTTACDFRLMTEESviRFVHKE--MGIVPSWGGASRLVEIIGSRQAL 201
Cdd:PRK09674  82 PQLWQR--LQAFNK-PLI--AAVNGYALGAGCELALLCDIVIAGENA--RFGLPEitLGIMPGAGGTQRLIRSVGKSLAS 154

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 56090598  202 K-VLSGTfKLDSKEALRIGLADEVLQPsdeATALEQAQEWLEQFVSGPAQVIRGLKKSVCSGRELYLEEALQNERDVLET 280
Cdd:PRK09674 155 QmVLTGE-SITAQQAQQAGLVSEVFPP---ELTLERALQLASKIARHSPLALRAAKQALRQSQEVDLQAGLAQERQLFTL 230

                        250
                 ....*....|..
gi 56090598  281 LWGGPANLEAIA 292
Cdd:PRK09674 231 LAATEDRHEGIS 242
PRK05862 PRK05862
enoyl-CoA hydratase; Provisional
 56-283 8.50e-19

enoyl-CoA hydratase; Provisional


Pssm-ID: 180295 [Multi-domain]  Cd Length: 257  Bit Score: 83.55  E-value: 8.50e-19
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 56090598   56 IGILTLNNSNKMNAFSGAMMLQLLERVIELENwTEGKGLIV-HGAKNTFCSGSDLNAVKALSTPEngVALSMFMQN--TL 132
Cdd:PRK05862  14 VGLITLNRPKALNALNDALMDELGAALAAFDA-DEGIGAIViTGSEKAFAAGADIKEMADLSFMD--VYKGDYITNweKV 90

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 56090598  133 TRfMRLPLIsvALVQGWAMGGGAELTTACDFRLMTEESviRFVHKE--MGIVPSWGGASRLVEIIGSRQALK-VLSGTFk 209
Cdd:PRK05862  91 AR-IRKPVI--AAVAGYALGGGCELAMMCDIIIAADTA--KFGQPEikLGVLPGMGGSQRLTRAVGKAKAMDlCLTGRM- 164

                        170       180       190       200       210       220       230
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 56090598  210 LDSKEALRIGLADEVLqPSDEatALEQAQEWLEQFVSGPAQVIRGLKKSVCSGRELYLEEALQNERDVLETLWG 283
Cdd:PRK05862 165 MDAAEAERAGLVSRVV-PADK--LLDEALAAATTIASFSLPAVMMAKEAVNRAYETTLAEGLLFERRLFHSLFA 235
PRK07509 PRK07509
crotonase/enoyl-CoA hydratase family protein;
52-299 8.68e-19

crotonase/enoyl-CoA hydratase family protein;


Pssm-ID: 181008 [Multi-domain]  Cd Length: 262  Bit Score: 83.78  E-value: 8.68e-19
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 56090598   52 KQNGIGILTLNNSNKMNAFSGAMMLQLLERVIELENWTEGKGLIVHGAKNTFCSGSDLNAVkaLSTPENGVAL----SMF 127
Cdd:PRK07509   9 IEDGIADVRLNRPDKMNALDFAMFEELIATIKRLKKDRGIRAVILSGEGGAFCAGLDVKSV--ASSPGNAVKLlfkrLPG 86

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 56090598  128 MQNTLTRFM----RLPLISVALVQGWAMGGGAELTTACDFRLMTEESviRFVHKEM--GIVPSWGGASRLVEIIGSRQAL 201
Cdd:PRK07509  87 NANLAQRVSlgwrRLPVPVIAALEGVCFGGGLQIALGADIRIAAPDT--KLSIMEAkwGLVPDMAGTVSLRGLVRKDVAR 164

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 56090598  202 KvLSGTFK-LDSKEALRIGLADEVlqpSDE--ATALEQAQEWLEQfvsGPAqVIRGLKKS-----VCSGRELYLEEALQN 273
Cdd:PRK07509 165 E-LTYTARvFSAEEALELGLVTHV---SDDplAAALALAREIAQR---SPD-AIAAAKRLinrswTASVRALLARESVEQ 236

                        250       260
                 ....*....|....*....|....*.
gi 56090598  274 ERdvletLWGGPANLEAIAKKGKHTK 299
Cdd:PRK07509 237 IR-----LLLGKNQKIAVKAQMKKRA 257
PRK07659 PRK07659
enoyl-CoA hydratase; Provisional
 51-276 2.50e-18

enoyl-CoA hydratase; Provisional


Pssm-ID: 236073 [Multi-domain]  Cd Length: 260  Bit Score: 82.39  E-value: 2.50e-18
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 56090598   51 KKQNGIGILTLNNSNKMNAFSGAMMLQLLERVIELENwTEGKGLIVHGAKNTFCSGSDLNAVKALSTPENGVALSMFMQN 130
Cdd:PRK07659  11 KYEGRVATIMLNRPEALNALDEPMLKELLQALKEVAE-SSAHIVVLRGNGRGFSAGGDIKMMLSSNDESKFDGVMNTISE 89

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 56090598  131 TLTRFMRLPLISVALVQGWAMGGGAELTTACDFRLMTEESVIRFVHKEMGIVPSWGGASRLVEIIGSRQALKVLSGTFKL 210
Cdd:PRK07659  90 IVVTLYTMPKLTISAIHGPAAGLGLSIALTADYVIADISAKLAMNFIGIGLIPDGGGHFFLQKRVGENKAKQIIWEGKKL 169

                        170       180       190       200       210       220
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 56090598  211 DSKEALRIGLADEVLqpsdEATALEQAQEWLEQFVSGPAQVIRGLKKSVCSGRELYLEEALQNERD 276
Cdd:PRK07659 170 SATEALDLGLIDEVI----GGDFQTAAKQKISEWLQKPLKAMIETKQIYCELNRSQLEQVLQLEKR 231
PRK05981 PRK05981
enoyl-CoA hydratase/isomerase;
53-275 1.07e-17

enoyl-CoA hydratase/isomerase;


Pssm-ID: 235661  Cd Length: 266  Bit Score: 80.93  E-value: 1.07e-17
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 56090598   53 QNGIGILTLNNSNKMNAFSGAMMLQLLE--RVIElENWTEGKGLIVHGAKNTFCSGSDL----NAVK-ALSTPENGVALS 125
Cdd:PRK05981  11 DGGVAILTLDHPEVMNAVSIDMLGGLAEalDAIE-DGKAEVRCLVLTGAGRGFCTGANLqgrgSGGReSDSGGDAGAALE 89

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 56090598  126 MFMQNTLTRFMRLPLISVALVQGWAMGGGAELTTACDFRLMTEESVIRFVHKEMGIVPSWGGASRLVEIIGSRQALKVLS 205
Cdd:PRK05981  90 TAYHPFLRRLRNLPCPIVTAVNGPAAGVGMSFALMGDLILCARSAYFLQAFRRIGLVPDGGSTWLLPRLVGKARAMELSL 169

                        170       180       190       200       210       220       230
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 56090598  206 GTFKLDSKEALRIGLADEVLqpsDEATALEQAQEWLEQFVSGPAQVIRGLKKSVCSGRELYLEEALQNER 275
Cdd:PRK05981 170 LGEKLPAETALQWGLVNRVV---DDAELMAEAMKLAHELANGPTVALGLIRKLYWDSPENDFEEQLNLER 236
PRK09076 PRK09076
enoyl-CoA hydratase; Provisional
 51-292 5.77e-17

enoyl-CoA hydratase; Provisional


Pssm-ID: 236373 [Multi-domain]  Cd Length: 258  Bit Score: 78.81  E-value: 5.77e-17
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 56090598   51 KKQNGIGILTLNNSnKMNAFSGAMMLQLLERVIELENWTEGKGLIVHGAKNTF-CSGSDLNAvkaLSTPENGVALSM--- 126
Cdd:PRK09076   8 EIDGHVAILTLNNP-PANTWTADSLQALKQLVLELNADKDVYALVITGDGEKFfSAGADLNL---FADGDKAVAREMarr 83

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 56090598  127 FMQ--NTLTRFMRlplISVALVQGWAMGGGAELTTACDFRLMTEESVIRFVHKEMGIVPSWGGASRLVEIIGSRQALK-V 203
Cdd:PRK09076  84 FGEafEALSAFRG---VSIAAINGYAMGGGLECALACDIRIAEEQAQMALPEASVGLLPCAGGTQNLPWLVGEGWAKRmI 160

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 56090598  204 LSGTfKLDSKEALRIGLADEVLqpsDEATALEQAQEWLEQFVSGPAQVIRGLKKSVCSGRELYLEEALQNERDVLETLWG 283
Cdd:PRK09076 161 LCGE-RVDAATALRIGLVEEVV---EKGEAREAALALAQKVANQSPSAVAACKTLIQAARNGPRAAALALERELFVDLFD 236


                 ....*....
gi 56090598  284 GPANLEAIA 292
Cdd:PRK09076 237 TEDQREGVN 245
PRK06563 PRK06563
crotonase/enoyl-CoA hydratase family protein;
52-239 8.06e-17

crotonase/enoyl-CoA hydratase family protein;


Pssm-ID: 180625 [Multi-domain]  Cd Length: 255  Bit Score: 78.08  E-value: 8.06e-17
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 56090598   52 KQNGIGILTLNNSNKMNAFSGAMMLQLLERVIELENWTEGKGLIVHGAKNTFCSGSDLNAV------KALSTPENGVALS 125
Cdd:PRK06563   5 RRGHVLLIGLDRPAKRNAFDSAMLDDLALALGEYEADDELRVAVLFAHGEHFTAGLDLADVapklaaGGFPFPEGGIDPW 84

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 56090598  126 MFMQNTLTRfmrlPLISValVQGWAMGGGAELTTACDFRLMTEESviRFVHKEM--GIVPSWGGASRLVEIIGSRQALKV 203
Cdd:PRK06563  85 GTVGRRLSK----PLVVA--VQGYCLTLGIELMLAADIVVAADNT--RFAQLEVqrGILPFGGATLRFPQAAGWGNAMRY 156

                        170       180       190
                 ....*....|....*....|....*....|....*..
gi 56090598  204 LSGTFKLDSKEALRIGLADEVLQPSDE-ATALEQAQE 239
Cdd:PRK06563 157 LLTGDEFDAQEALRLGLVQEVVPPGEQlERAIELAER 193
PRK08258 PRK08258
enoyl-CoA hydratase family protein;
53-249 8.13e-17

enoyl-CoA hydratase family protein;


Pssm-ID: 181329  Cd Length: 277  Bit Score: 78.47  E-value: 8.13e-17
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 56090598   53 QNGIGILTLNNSNKMNAFSGAMMLQLLERVIELENWTEGKGLIVHGAKNTFCSGSDLN----AVKALSTPEngvaLSMF- 127
Cdd:PRK08258  24 DDGVATITLNRPERKNPLTFESYAELRDLFRELVYADDVKAVVLTGAGGNFCSGGDVHeiigPLTKMDMPE----LLAFt 99

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 56090598  128 -MQNTLTRFMR-LPLISVALVQGWAMGGGAELTTACDFRLMTEESVIRFVHKEMGIVPS-WGGASRLVEIIGSRQALKVL 204
Cdd:PRK08258 100 rMTGDLVKAMRaCPQPIIAAVDGVCAGAGAILAMASDLRLGTPSAKTAFLFTRVGLAGAdMGACALLPRIIGQGRASELL 179

                        170       180       190       200
                 ....*....|....*....|....*....|....*....|....*
gi 56090598  205 SGTFKLDSKEALRIGLADEVLQPSDeatALEQAQEWLEQFVSGPA 249
Cdd:PRK08258 180 YTGRSMSAEEGERWGFFNRLVEPEE---LLAEAQALARRLAAGPT 221
PRK07799 PRK07799
crotonase/enoyl-CoA hydratase family protein;
43-295 1.21e-16

crotonase/enoyl-CoA hydratase family protein;


Pssm-ID: 181122 [Multi-domain]  Cd Length: 263  Bit Score: 77.84  E-value: 1.21e-16
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 56090598   43 PGGSIDLQKKQNG-IGILTLNNSNKMNAFSGAMMLQLLERVIELENWTEGKGLIVHGAKNTFCSGSDLNAVkALSTPENG 121
Cdd:PRK07799   1 MEGGPHALVEQRGhTLIVTMNRPEARNALSTEMLRIMVDAWDRVDNDPDIRSCILTGAGGAFCAGMDLKAA-TKKPPGDS 79

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 56090598  122 VALSMFMQNTLT-----RFMRLPLIsvALVQGWAMGGGAELTTACDFRLMTEESVIRFVHKEMGIVPSWGGASRLVEIIG 196
Cdd:PRK07799  80 FKDGSYDPSRIDallkgRRLTKPLI--AAVEGPAIAGGTEILQGTDIRVAGESAKFGISEAKWSLFPMGGSAVRLVRQIP 157

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 56090598  197 SRQALKVLSGTFKLDSKEALRIGLADEVLqpsDEATALEQAQEWLEQF-VSGPAQViRGLKKSVCSGRELYLEEALQner 275
Cdd:PRK07799 158 YTVACDLLLTGRHITAAEAKEIGLIGHVV---PDGQALDKALELAELInANGPLAV-QAILRTIRETEGMHENEAFK--- 230

                        250       260
                 ....*....|....*....|
gi 56090598  276 dvLETLWGGPANLEAIAKKG 295
Cdd:PRK07799 231 --IDTKIGIPVFLSEDAKEG 248
PRK08252 PRK08252
crotonase/enoyl-CoA hydratase family protein;
55-239 2.41e-16

crotonase/enoyl-CoA hydratase family protein;


Pssm-ID: 181325 [Multi-domain]  Cd Length: 254  Bit Score: 76.95  E-value: 2.41e-16
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 56090598   55 GIGILTLNNSNKMNAFSGAMMLQLLERVIELENWTEGKGLIVHGAKNTFCSGSDLNAV---KALSTPENGVAlsmfmqnT 131
Cdd:PRK08252  12 RVLIITINRPEARNAVNAAVAQGLAAALDELDADPDLSVGILTGAGGTFCAGMDLKAFargERPSIPGRGFG-------G 84

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 56090598  132 LT-RFMRLPLIsvALVQGWAMGGGAELTTACDFRLMTEESviRFVHKEM--GIVPSWGGASRLVEIIGSRQALK-VLSGT 207
Cdd:PRK08252  85 LTeRPPRKPLI--AAVEGYALAGGFELALACDLIVAARDA--KFGLPEVkrGLVAAGGGLLRLPRRIPYHIAMElALTGD 160

                        170       180       190
                 ....*....|....*....|....*....|...
gi 56090598  208 FkLDSKEALRIGLADEVLQPSDE-ATALEQAQE 239
Cdd:PRK08252 161 M-LTAERAHELGLVNRLTEPGQAlDAALELAER 192
fa_ox_alpha_mit TIGR02441
fatty acid oxidation complex, alpha subunit, mitochondrial; Members represent alpha subunit of ...
 51-250 3.33e-16

fatty acid oxidation complex, alpha subunit, mitochondrial; Members represent alpha subunit of mitochondrial multifunctional fatty acid degradation enzyme complex. Subunit activities include: enoyl-CoA hydratase (EC 4.2.1.17) _ 3-hydroxyacyl-CoA dehydrogenase (EC 1.1.1.35). Some characterization in human (SP:P40939), pig (SP:Q29554), and rat (SP:Q64428). The beta subunit has activity: acetyl-CoA C-acyltransferase (EC 2.3.1.16).


Pssm-ID: 131494 [Multi-domain]  Cd Length: 737  Bit Score: 78.73  E-value: 3.33e-16
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 56090598    51 KKQNGIGILTLNNSN-KMNAFSGAMMLQLLERVIELENWTEGKGLIVHGAK-NTFCSGSDLNAVKALSTPENGVALSMFM 128
Cdd:TIGR02441  18 EVKGDVAVVKIDSPNsKVNTLSKELFAEFKEVMNELWTNEAIKSAVLISGKpGSFVAGADIQMIAACKTAQEVTQLSQEG 97

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 56090598   129 QNTLTRFMRLPLISVALVQGWAMGGGAELTTACDFRLMTEESVIRFVHKE--MGIVPSWGGASRLVEIIGSRQALKVLSG 206
Cdd:TIGR02441  98 QEMFERIEKSQKPIVAAISGSCLGGGLELALACHYRIATKDRKTLLGLPEvmLGLLPGAGGTQRLPKLTGVPAALDMMLT 177

                         170       180       190       200
                  ....*....|....*....|....*....|....*....|....*.
gi 56090598   207 TFKLDSKEALRIGLADEVLQPSDEAT--ALEQAQEWLEQFVSGPAQ 250
Cdd:TIGR02441 178 GKKIRADRAKKMGIVDQLVDPLGPGLkpAEENTIEYLEEVAVKFAQ 223
PRK09245 PRK09245
crotonase/enoyl-CoA hydratase family protein;
49-272 6.77e-16

crotonase/enoyl-CoA hydratase family protein;


Pssm-ID: 181723  Cd Length: 266  Bit Score: 75.78  E-value: 6.77e-16
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 56090598   49 LQKKQNGIGILTLNNSNKMNAFSGAMMLQLLERVIELENWTEG-KGLIVHGAKNTFCSGSDlnaVKALSTPENGVALSMF 127
Cdd:PRK09245   6 LVERDGHIVTLTMNRPETRNALSDNDAVDALVAACAAINADRSvRAVILTGAGTAFSSGGN---VKDMRARVGAFGGSPA 82

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 56090598  128 MQNTLTR--FMRLPLI-------SVALVQGWAMGGGAELTTACDFRLMTEESVI--RFVhkEMGIVPSWGGASRLVEIIG 196
Cdd:PRK09245  83 DIRQGYRhgIQRIPLAlynlevpVIAAVNGPAIGAGCDLACMCDIRIASETARFaeSFV--KLGLIPGDGGAWLLPRIIG 160

                        170       180       190       200       210       220       230
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 56090598  197 -SRQALKVLSGTfKLDSKEALRIGLADEVLQPSDeatALEQAQEWLEQFVSGPAQVIRGLKKSVCSGRELYLEEALQ 272
Cdd:PRK09245 161 mARAAEMAFTGD-AIDAATALEWGLVSRVVPADQ---LLPAARALAERIAANPPHALRLTKRLLREGQHASLDTLLE 233
PRK08140 PRK08140
enoyl-CoA hydratase; Provisional
 53-276 7.73e-16

enoyl-CoA hydratase; Provisional


Pssm-ID: 236163  Cd Length: 262  Bit Score: 75.72  E-value: 7.73e-16
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 56090598   53 QNGIGILTLNNSNKMNAFSGAMMLQLLERVIELENwTEGKGLIVHGAKNTFCSG---SDLNAVKALSTPENGVALSMFMQ 129
Cdd:PRK08140  11 EAGVATLTLNRPDKLNSFTREMHRELREALDQVED-DGARALLLTGAGRGFCAGqdlADRDVTPGGAMPDLGESIETFYN 89

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 56090598  130 NTLTRFMRLPLISVALVQGWAMGGGAELTTACDFRLMTEESviRFVHK--EMGIVPSWGGASRLVEIIGSRQALKV-LSG 206
Cdd:PRK08140  90 PLVRRLRALPLPVIAAVNGVAAGAGANLALACDIVLAARSA--SFIQAfvKIGLVPDSGGTWFLPRLVGMARALGLaLLG 167

                        170       180       190       200       210       220       230
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 56090598  207 TfKLDSKEALRIGLadeVLQPSDEATALEQAQEWLEQFVSGPAQVIRGLKKSVCSGRELYLEEALQNERD 276
Cdd:PRK08140 168 E-KLSAEQAEQWGL---IWRVVDDAALADEAQQLAAHLATQPTRGLALIKQAMNASATNTLDAQLDLERD 233
PRK03580 PRK03580
crotonobetainyl-CoA hydratase;
49-271 1.48e-15

crotonobetainyl-CoA hydratase;


Pssm-ID: 179599 [Multi-domain]  Cd Length: 261  Bit Score: 74.73  E-value: 1.48e-15
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 56090598   49 LQKKQNGiGIL--TLNNSnKMNAFSGAMMLQLLERVIELENWTEGKGLIVHGA-KNTFCSGSDLNAVKALSTPENGVALS 125
Cdd:PRK03580   5 LHTTRNG-SILeiTLDRP-KANAIDAKTSFAMGEVFLNFRDDPELRVAIITGAgEKFFSAGWDLKAAAEGEAPDADFGPG 82

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 56090598  126 MFMQNTLTRFMRLPLIsvALVQGWAMGGGAELTTACDFRLMTEESVIRFVHKEMGIVPSWGGASRLVEIIGSRQALKVLS 205
Cdd:PRK03580  83 GFAGLTEIFDLDKPVI--AAVNGYAFGGGFELALAADFIVCADNASFALPEAKLGIVPDSGGVLRLPKRLPPAIANEMVM 160

                        170       180       190       200       210       220
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 56090598  206 GTFKLDSKEALRIGLADEVLqPSDEatALEQAQEWLEQFVSGPAQVIRGLKKSVCSGRELYLEEAL 271
Cdd:PRK03580 161 TGRRMDAEEALRWGIVNRVV-PQAE--LMDRARELAQQLVNSAPLAIAALKEIYRETSEMPVEEAY 223
PRK06142 PRK06142
crotonase/enoyl-CoA hydratase family protein;
54-256 2.64e-15

crotonase/enoyl-CoA hydratase family protein;


Pssm-ID: 235714  Cd Length: 272  Bit Score: 74.24  E-value: 2.64e-15
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 56090598   54 NGIGILTLNNSNKMNAFSGAMMLQLLERVIELENWTEGKGLIVHGAKNTFCSGSDLNAVKALSTP--ENGVALS------ 125
Cdd:PRK06142  14 DHVAQVTLNRPGKGNAMNPAFWSELPEIFRWLDADPEVRAVVLSGSGKHFSYGIDLPAMAGVFGQlgKDGLARPrtdlrr 93

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 56090598  126 --MFMQNTLTRF--MRLPLIsvALVQGWAMGGGAELTTACDFRLMTEESviRFVHKE--MGIVPSWGGASRLVEIIGSRQ 199
Cdd:PRK06142  94 eiLRLQAAINAVadCRKPVI--AAVQGWCIGGGVDLISACDMRYASADA--KFSVREvdLGMVADVGSLQRLPRIIGDGH 169

                        170       180       190       200       210
                 ....*....|....*....|....*....|....*....|....*....|....*...
gi 56090598  200 aLKVLSGTFK-LDSKEALRIGLADEVLqpSDEATALEQAQEWLEQFVSGPAQVIRGLK 256
Cdd:PRK06142 170 -LRELALTGRdIDAAEAEKIGLVNRVY--DDADALLAAAHATAREIAAKSPLAVRGTK 224
PRK08150 PRK08150
crotonase/enoyl-CoA hydratase family protein;
53-239 8.35e-15

crotonase/enoyl-CoA hydratase family protein;


Pssm-ID: 181254  Cd Length: 255  Bit Score: 72.36  E-value: 8.35e-15
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 56090598   53 QNGIGILTLNNSNKMNAFSGAMMLQLLERVIELENwtEGKGLIVHGAKNTFCSGSDLNAVKALSTPEnGVALSMFMQNTL 132
Cdd:PRK08150   9 DGGVATIGLNRPAKRNALNDGLIAALRAAFARLPE--GVRAVVLHGEGDHFCAGLDLSELRERDAGE-GMHHSRRWHRVF 85

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 56090598  133 TRFMRLPLISVALVQGWAMGGGAELTTACDFRLMTEESVIRFVHKEMGIVPSWGGASRLVEIIG-SRQALKVLSGTFkLD 211
Cdd:PRK08150  86 DKIQYGRVPVIAALHGAVVGGGLELASAAHIRVADESTYFALPEGQRGIFVGGGGSVRVPRLIGvARMTDMMLTGRV-YD 164

                        170       180
                 ....*....|....*....|....*...
gi 56090598  212 SKEALRIGLADEVLQPSdeaTALEQAQE 239
Cdd:PRK08150 165 AQEGERLGLAQYLVPAG---EALDKAME 189
PLN03214 PLN03214
probable enoyl-CoA hydratase/isomerase; Provisional
 43-269 1.19e-14

probable enoyl-CoA hydratase/isomerase; Provisional


Pssm-ID: 215635  Cd Length: 278  Bit Score: 72.61  E-value: 1.19e-14
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 56090598   43 PGGSIDLQKKQNGIGILTLNnSNKMNAFSGAMMLQLLERVIELENWTEGKGLIVHGA--KNTFCSGSDLNAVKALSTPEN 120
Cdd:PLN03214   9 ATPGVRVDRRPGGIAVVWLA-KEPVNSMTLAMWRSLDDALTALENDPTVRGVVFASGlrRDVFTAGNDIAELYAPKTSAA 87

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 56090598  121 GVALSMFMQNT-LTRFMRLPLISVALVQGWAMGGGAELTTACDFRLMTEESVIRFVHKEMGI-VPSWGGASRLVEIIGSR 198
Cdd:PLN03214  88 RYAEFWLTQTTfLVRLLRSRLATVCAIRGACPAGGCAVSLCCDYRLQTTEGTMGLNEVALGIpVPKFWARLFMGRVIDRK 167

                        170       180       190       200       210       220       230
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 56090598  199 QALKVLSGTFKLDSKEALRIGLADEVLQpsdEATALEQAQEWLEQFVSGP----AQVIRGLKKSVCSGRELYLEE 269
Cdd:PLN03214 168 VAESLLLRGRLVRPAEAKQLGLIDEVVP---AAALMEAAASAMERALKLPsaarAATKALLREEFSAAWEAYYEE 239
PLN02988 PLN02988
3-hydroxyisobutyryl-CoA hydrolase
 49-235 1.52e-13

3-hydroxyisobutyryl-CoA hydrolase


Pssm-ID: 178568 [Multi-domain]  Cd Length: 381  Bit Score: 70.13  E-value: 1.52e-13
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 56090598   49 LQKKQNGIGILTLNNSNKMNAFSGAMMLQLLERVIELENWTEGKGLIVHGAKNTFCSGSDLNA-VKALSTPENGVALSMF 127
Cdd:PLN02988  12 LVEEKSSVRILTLNRPKQLNALSFHMISRLLQLFLAFEEDPSVKLVILKGHGRAFCAGGDVAAvVRDIEQGNWRLGANFF 91

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 56090598  128 MQNTLTRFMRLPL--ISVALVQGWAMGGGAELTTACDFRLMTEESVIRFVHKEMGIVPSWGGASRLVEIIGSRQALKVLS 205
Cdd:PLN02988  92 SDEYMLNYVMATYskAQVSILNGIVMGGGAGVSVHGRFRIATENTVFAMPETALGLFPDVGASYFLSRLPGFFGEYVGLT 171

                        170       180       190
                 ....*....|....*....|....*....|
gi 56090598  206 GTfKLDSKEALRIGLADEVLqPSDEATALE 235
Cdd:PLN02988 172 GA-RLDGAEMLACGLATHFV-PSTRLTALE 199
menB TIGR01929
naphthoate synthase (dihydroxynaphthoic acid synthetase); This model represents an enzyme, ...
 47-258 1.60e-13

naphthoate synthase (dihydroxynaphthoic acid synthetase); This model represents an enzyme, naphthoate synthase (dihydroxynaphthoic acid synthetase), which is involved in the fifth step of the menaquinone biosynthesis pathway. Together with o-succinylbenzoate-CoA ligase (menE: TIGR01923), this enzyme takes 2-succinylbenzoate and converts it into 1,4-di-hydroxy-2-naphthoate. Included above the trusted cutoff are two enzymes from Arabadopsis thaliana and one from Staphylococcus aureus which are identified as putative enoyl-CoA hydratase/isomerases. These enzymes group with the naphthoate synthases when building a tree and when doing BLAST searches. [Biosynthesis of cofactors, prosthetic groups, and carriers, Menaquinone and ubiquinone]


Pssm-ID: 200143 [Multi-domain]  Cd Length: 259  Bit Score: 69.11  E-value: 1.60e-13
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 56090598    47 IDLQKKQNGIGILTLNNSNKMNAFSGAMMLQLLeRVIELENWTEGKGLIV---HGAKnTFCSGSDlNAVKALS--TPENG 121
Cdd:TIGR01929   4 IRYEKSTDGIAKITINRPQVRNAFRPLTVKEII-QALDDAREDPDIGVVIltgAGDK-AFCSGGD-QKVRGDYgyIDDSG 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 56090598   122 VA-LSMFMQNTLTRFMRLPLIsvALVQGWAMGGGAELTTACDFRLMTEESVIRFVHKEMGIVPSWGGASRLVEIIGSRQA 200
Cdd:TIGR01929  81 VHrLNVLDVQRQIRTCPKPVI--AMVNGYAIGGGHVLHMMCDLTIAAENARFGQTGPKVGSFDGGYGSSYMARIVGQKKA 158

                         170       180       190       200       210
                  ....*....|....*....|....*....|....*....|....*....|....*....
gi 56090598   201 LKVLSGTFKLDSKEALRIGLADEVLQPSDeataLEQAQ-EWLEQFVSGPAQVIRGLKKS 258
Cdd:TIGR01929 159 REIWFLCRQYDAKQALDMGLVNTVVPLAD----LEKETvRWCREILQKSPMAIRMLKAA 213
PRK05995 PRK05995
enoyl-CoA hydratase; Provisional
 59-259 1.73e-13

enoyl-CoA hydratase; Provisional


Pssm-ID: 235664 [Multi-domain]  Cd Length: 262  Bit Score: 68.80  E-value: 1.73e-13
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 56090598   59 LTLNNSNKMNAFSGAMMLQLLERVIELENWTEGKGLIVHGAKNTFCSGSDLNAVKALS--TPENGVALSMFMQNTLTRFM 136
Cdd:PRK05995  17 VTLNRPDVRNAFNETVIAELTAAFRALDADDSVRAVVLAGAGKAFCAGADLNWMKKMAgySDDENRADARRLADMLRAIY 96

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 56090598  137 RLPLISVALVQGWAMGGGAELTTACDFRLMTEESVIRFVHKEMGIVPSwGGASRLVEIIGSRQALK-VLSGTfKLDSKEA 215
Cdd:PRK05995  97 RCPKPVIARVHGDAYAGGMGLVAACDIAVAADHAVFCLSEVRLGLIPA-TISPYVIRAMGERAARRyFLTAE-RFDAAEA 174

                        170       180       190       200
                 ....*....|....*....|....*....|....*....|....*
gi 56090598  216 LRIGLADEVLqpsdEATALEQAQEWL-EQFVSGPAQVIRGLKKSV 259
Cdd:PRK05995 175 LRLGLVHEVV----PAEALDAKVDELlAALVANSPQAVRAGKRLV 215
PRK05864 PRK05864
enoyl-CoA hydratase; Provisional
 55-220 2.19e-13

enoyl-CoA hydratase; Provisional


Pssm-ID: 168278 [Multi-domain]  Cd Length: 276  Bit Score: 68.71  E-value: 2.19e-13
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 56090598   55 GIGILTLNNSNKMNAFSGAMMLQLLERVIELENWTEGKGLIVHGAKNTFCSGSDLNA------VKALSTPENGVALSMFM 128
Cdd:PRK05864  19 EIALITLNRPERMNSMAFDVMVPLKEALAEVSYDNSVRVVVLTGAGRGFSSGADHKSagvvphVEGLTRPTYALRSMELL 98

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 56090598  129 QNTLTRFMRLPLISVALVQGWAMGGGAELTTACDFRLMTEESVIRFVHKEMGIVPSWGGASRLV-EIIGSRQALKVLSGT 207
Cdd:PRK05864  99 DDVILALRRLHQPVIAAVNGPAIGGGLCLALAADIRVASSSAYFRAAGINNGLTASELGLSYLLpRAIGSSRAFEIMLTG 178

                        170
                 ....*....|...
gi 56090598  208 FKLDSKEALRIGL 220
Cdd:PRK05864 179 RDVDAEEAERIGL 191
PLN02664 PLN02664
enoyl-CoA hydratase/delta3,5-delta2,4-dienoyl-CoA isomerase
 59-271 4.51e-13

enoyl-CoA hydratase/delta3,5-delta2,4-dienoyl-CoA isomerase


Pssm-ID: 178269 [Multi-domain]  Cd Length: 275  Bit Score: 68.00  E-value: 4.51e-13
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 56090598   59 LTLNNSNKMNAFSGAMMLQLLERVIELENWTEGKGLIVHGAKNTFCSGSDLNAVKALSTP-------ENGVALS---MFM 128
Cdd:PLN02664  21 LNLNRPSQRNALSLDFFTEFPKALSSLDQNPNVSVIILSGAGDHFCSGIDLKTLNSISEQsssgdrgRSGERLRrkiKFL 100

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 56090598  129 QNTLTRFMRLPLISVALVQGWAMGGGAELTTACDFRLMTEESVIRFVHKEMGIVPSWGGASRLVEIIGSRQALKVLSGTF 208
Cdd:PLN02664 101 QDAITAIEQCRKPVIAAIHGACIGGGVDIVTACDIRYCSEDAFFSVKEVDLAITADLGTLQRLPSIVGYGNAMELALTGR 180

                        170       180       190       200       210       220
                 ....*....|....*....|....*....|....*....|....*....|....*....|....
gi 56090598  209 KLDSKEALRIGLADEVLQPSDEataLEQAQEWLEQFVSGPAQV-IRGLKKSVCSGRELYLEEAL 271
Cdd:PLN02664 181 RFSGSEAKELGLVSRVFGSKED---LDEGVRLIAEGIAAKSPLaVTGTKAVLLRSRELSVEQGL 241
PRK07511 PRK07511
enoyl-CoA hydratase; Provisional
 49-292 4.70e-13

enoyl-CoA hydratase; Provisional


Pssm-ID: 181009 [Multi-domain]  Cd Length: 260  Bit Score: 67.71  E-value: 4.70e-13
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 56090598   49 LQKKQNGIGILTLNNSNKMNAFSGAMMLQLLERVIELENWTEGKGLIVHGAKNTFCSGSDLNAV-KALSTPENGVALSMF 127
Cdd:PRK07511   6 LSRREGSTLVLTLSNPGARNALHPDMYAAGIEALNTAERDPSIRAVVLTGAGGFFCAGGNLNRLlENRAKPPSVQAASID 85

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 56090598  128 MQNTLTRFMR-LPLISVALVQGWAMGGGAELTTACDFRLMTEESVIRFVHKEMGIVPSWGGASRLVEIIgSRQALKVLSG 206
Cdd:PRK07511  86 GLHDWIRAIRaFPKPVIAAVEGAAAGAGFSLALACDLLVAARDAKFVMAYVKVGLTPDGGGSWFLARAL-PRQLATELLL 164

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 56090598  207 TFKLDSKEALR-IGLADEVLQPsdeATALEQAQEWLEQFVSGPAQVIRGLKKSVCSGRELYLEEALQNERDVLETLWGGP 285
Cdd:PRK07511 165 EGKPISAERLHaLGVVNRLAEP---GQALAEALALADQLAAGSPNALARIKSLIADAPEATLAAQLEAERDHFVASLHHA 241


                 ....*..
gi 56090598  286 ANLEAIA 292
Cdd:PRK07511 242 DALEGIA 248
PRK06210 PRK06210
enoyl-CoA hydratase; Provisional
 55-278 5.68e-13

enoyl-CoA hydratase; Provisional


Pssm-ID: 180472  Cd Length: 272  Bit Score: 67.42  E-value: 5.68e-13
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 56090598   55 GIGILTLNNSNKMNAFsGAMMLQLLERVIELENWTEGKGLIV-HGAKNTFCSGSDLNAVKALStPENGVA---LSMFMQN 130
Cdd:PRK06210  15 GVAVITLNRPDRLNAW-TPVMEAEVYAAMDRAEADPAVRVIVlTGAGRGFCAGADMGELQTID-PSDGRRdtdVRPFVGN 92

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 56090598  131 ----TLTRF-----MRLPLIsvALVQGWAMGGGAELTTACDFRLMTEESVIRFVHKEMGIVPSWGGASRLVEIIGSRQAL 201
Cdd:PRK06210  93 rrpdYQTRYhfltaLRKPVI--AAINGACAGIGLTHALMCDVRFAADGAKFTTAFARRGLIAEHGISWILPRLVGHANAL 170

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 56090598  202 KVLSGTFKLDSKEALRIGLADEVLQPSD-EATALEQAQEwLEQFVSgPA--QVIRglkksvcsgRELYlEEALQNERDVL 278
Cdd:PRK06210 171 DLLLSARTFYAEEALRLGLVNRVVPPDElMERTLAYAED-LARNVS-PAsmAVIK---------RQLY-EDAFQTLAEAT 238
PRK06143 PRK06143
enoyl-CoA hydratase; Provisional
 54-273 9.29e-13

enoyl-CoA hydratase; Provisional


Pssm-ID: 180423  Cd Length: 256  Bit Score: 66.60  E-value: 9.29e-13
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 56090598   54 NGIGILTLNNSNKMNAFSGAMMLQLLERVIELENWTEGKGLIVHGA-KNTFCSGSDLNAVKALsTPENGVALsmfmqntL 132
Cdd:PRK06143  15 RGVATLTIRNAGSLNILGTPVILALTQALRWLAADPDVRVLVLRGAgEKAFIGGADIKEMATL-DQASAEAF-------I 86

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 56090598  133 TRFMRL-------PLISVALVQGWAMGGGAELTTACDFRLMTEESVIRFVHKEMGIvPSWGGASRLVEIIG-SRQALKVL 204
Cdd:PRK06143  87 SRLRDLcdavrhfPVPVIARIPGWCLGGGLELAAACDLRIAAHDAQFGMPEVRVGI-PSVIHAALLPRLIGwARTRWLLL 165

                        170       180       190       200       210       220
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 56090598  205 SGTfKLDSKEALRIGLADEVLQPSDEATALEQAQEWLEQFvsGPaQVIRGLKKSVCSGRELYLEEALQN 273
Cdd:PRK06143 166 TGE-TIDAAQALAWGLVDRVVPLAELDAAVERLAASLAGC--GP-QALRQQKRLLREWEDMPLDVAIDD 230
PRK07854 PRK07854
enoyl-CoA hydratase; Provisional
 56-239 1.04e-12

enoyl-CoA hydratase; Provisional


Pssm-ID: 236115 [Multi-domain]  Cd Length: 243  Bit Score: 66.20  E-value: 1.04e-12
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 56090598   56 IGILTLNNSNKMNAFSGAMMLQLLERVIELENwTEGKGLIVHGAKNTFCSGSDLNA-VKALSTPENGVALsmfmqntLTR 134
Cdd:PRK07854  10 VLTIELQRPERRNALNAELCEELREAVRKAVD-ESARAIVLTGQGTVFCAGADLSGdVYADDFPDALIEM-------LHA 81

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 56090598  135 FMRLPLISVALVQGWAMGGGAELTTACDFRLMTEESVIRFVHKEMGI-VPSWgGASRLVEIIGSRQALKVLSGTFKLDSK 213
Cdd:PRK07854  82 IDAAPVPVIAAINGPAIGAGLQLAMACDLRVVAPEAYFQFPVAKYGIaLDNW-TIRRLSSLVGGGRARAMLLGAEKLTAE 160

                        170       180
                 ....*....|....*....|....*.
gi 56090598  214 EALRIGLADEVlqpSDEATALEQAQE 239
Cdd:PRK07854 161 QALATGMANRI---GTLADAQAWAAE 183
PRK07468 PRK07468
crotonase/enoyl-CoA hydratase family protein;
46-235 1.19e-12

crotonase/enoyl-CoA hydratase family protein;


Pssm-ID: 180987 [Multi-domain]  Cd Length: 262  Bit Score: 66.62  E-value: 1.19e-12
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 56090598   46 SIDLQKKQNGIGILTLNNSNKMNAFSGAMMLQLLERVIELENWTEGKGLIVHGAKNTFCSGSDLNAVKAL--STPENGVA 123
Cdd:PRK07468   5 TIRIAVDARGVATLTLNRPEKHNALSARMIAELTTAARRLAADAAVRVVVLTGAGKSFCAGGDLGWMRAQmtADRATRIE 84

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 56090598  124 ----LSMFMQ--NTLTRfmrlPLIsvALVQGWAMGGGAELTTACDFRLMTEESVIRFVHKEMGIVPSWGGaSRLVEIIGS 197
Cdd:PRK07468  85 earrLAMMLKalNDLPK----PLI--GRIQGQAFGGGVGLISVCDVAIAVSGARFGLTETRLGLIPATIS-PYVVARMGE 157

                        170       180       190
                 ....*....|....*....|....*....|....*...
gi 56090598  198 RQALKVLSGTFKLDSKEALRIGLADEVLQPSDEATALE 235
Cdd:PRK07468 158 ANARRVFMSARLFDAEEAVRLGLLSRVVPAERLDAAVE 195
PRK09120 PRK09120
p-hydroxycinnamoyl CoA hydratase/lyase; Validated
 54-270 1.75e-12

p-hydroxycinnamoyl CoA hydratase/lyase; Validated


Pssm-ID: 236383  Cd Length: 275  Bit Score: 66.19  E-value: 1.75e-12
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 56090598   54 NGIGILTLNNSNKMNAFSGAM---MLQLLErviELENWTEGKGLIVHGAKNTFCSGSDLNAVkALSTPENGVALSMFMQN 130
Cdd:PRK09120  16 DGIAWVTLNRPEKRNAMSPTLnreMIDVLD---ALEFDDDAGVLVLTGAGDAWSAGMDLKEY-FRETDAQPEILQERIRR 91

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 56090598  131 TLTRFMRL----PLISVALVQGWAMGGGAELTTACDFRLMTEESVIRFVHKEMGIVPSwGGASR-LVEIIGSRQAL-KVL 204
Cdd:PRK09120  92 EAYGWWRRlrwyQKPTIAMVNGWCFGGGFSPLVACDLAIAADEAQFGLSEINWGIPPG-GGVSKaMADTVGHRDALyYIM 170

                        170       180       190       200       210       220
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 56090598  205 SG-TFklDSKEALRIGLADEVLqPSDE--ATALEQAQEWLEQfvsGPAqVIRGLKKSVCSGRELYLEEA 270
Cdd:PRK09120 171 TGeTF--TGRKAAEMGLVNESV-PLAQlrARTRELAAKLLEK---NPV-VLRAAKDGFKRVRELTWDQA 232
PLN02851 PLN02851
3-hydroxyisobutyryl-CoA hydrolase-like protein
 61-221 3.08e-11

3-hydroxyisobutyryl-CoA hydrolase-like protein


Pssm-ID: 178443 [Multi-domain]  Cd Length: 407  Bit Score: 63.46  E-value: 3.08e-11
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 56090598   61 LNNSNKMNAFSgAMMLQLLERVieLENWTEGKGL---IVHGAKNTFCSGSDLNAVKALSTPENGVALSMFMQNtLTRFMR 137
Cdd:PLN02851  57 LNRPSSLNALT-IPMVARLKRL--YESWEENPDIgfvLMKGSGRAFCSGADVVSLYHLINEGNVEECKLFFEN-LYKFVY 132

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 56090598  138 L------PliSVALVQGWAMGGGAELTTACDFRLMTEESVIRFVHKEMGIVPSWGGA---SRLVEIIGSRQAlkvLSGTf 208
Cdd:PLN02851 133 LqgtylkP--NVAIMDGITMGCGAGISIPGMFRVVTDKTVFAHPEVQMGFHPDAGASyylSRLPGYLGEYLA---LTGQ- 206

                        170
                 ....*....|...
gi 56090598  209 KLDSKEALRIGLA 221
Cdd:PLN02851 207 KLNGVEMIACGLA 219
ECH_2 pfam16113
Enoyl-CoA hydratase/isomerase; This family contains a diverse set of enzymes including: ...
 56-237 3.24e-11

Enoyl-CoA hydratase/isomerase; This family contains a diverse set of enzymes including: enoyl-CoA hydratase, napthoate synthase, carnitate racemase, 3-hydroxybutyryl-CoA dehydratase and dodecanoyl-CoA delta-isomerase. This family differs from pfam00378 in the structure of it's C-terminus.


Pssm-ID: 465024 [Multi-domain]  Cd Length: 331  Bit Score: 62.87  E-value: 3.24e-11
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 56090598    56 IGILTLNNSNKMNAFSGAMMLQLLERVIELENWTEGKGLIVHGA-KNTFCSGSDLNAVKALSTPENGVALSMF------M 128
Cdd:pfam16113   1 VGVITLNRPKALNALNLEMVRALLAALKAWEDDPAVKLVVLKGAgERAFCAGGDVRALYEAAKAGGGEAGRDFfreeyrL 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 56090598   129 QNTLTRFMRlPLisVALVQGWAMGGGAELTTACDFRLMTEESviRFVHKEMGIvpswG-----GASRLVeiigSRqaLKV 203
Cdd:pfam16113  81 NYLIATYPK-PY--VALMDGIVMGGGVGLSVHGSFRVVTERT--RFAMPETAI----GlfpdvGGSYFL----SR--LPG 145

                         170       180       190       200
                  ....*....|....*....|....*....|....*....|
gi 56090598   204 LSGTF------KLDSKEALRIGLADEVLqPSDEATALEQA 237
Cdd:pfam16113 146 ELGLYlaltgaRLNGADALAAGLATHYV-PSARLPALEEA 184
PRK07110 PRK07110
polyketide biosynthesis enoyl-CoA hydratase; Validated
 46-274 7.03e-11

polyketide biosynthesis enoyl-CoA hydratase; Validated


Pssm-ID: 235936  Cd Length: 249  Bit Score: 61.14  E-value: 7.03e-11
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 56090598   46 SIDLQKKQNGIGILTLNNSNKMNAFSGAMMLQLLERVIELENWTEGKGLIVHGAKNTFCSGSDLNAVKALSTPENGVALS 125
Cdd:PRK07110   5 VVELREVEEGIAQVTMQDRVNKNAFSDELCDQLHEAFDTIAQDPRYKVVILTGYPNYFATGGTQEGLLSLQTGKGTFTEA 84

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 56090598  126 mfmqNTLTRFMRLPLISVALVQGWAMGGGAELTTACDFRLMTEESVIRFVHKEMGIVPSWGGASRLVEIIGSRQALKVLS 205
Cdd:PRK07110  85 ----NLYSLALNCPIPVIAAMQGHAIGGGLVLGLYADIVVLSRESVYTANFMKYGFTPGMGATAILPEKLGLALGQEMLL 160

                        170       180       190       200       210       220
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 56090598  206 GTFKLDSKEALRIGLADEVLqPSDEatALEQAQEWLEQFVSGPAQVIRGLKKSVCSGRELYLEEALQNE 274
Cdd:PRK07110 161 TARYYRGAELKKRGVPFPVL-PRAE--VLEKALELARSLAEKPRHSLVLLKDHLVADRRRRLPEVIEQE 226
PRK05674 PRK05674
gamma-carboxygeranoyl-CoA hydratase; Validated
 46-256 8.98e-11

gamma-carboxygeranoyl-CoA hydratase; Validated


Pssm-ID: 168168  Cd Length: 265  Bit Score: 60.98  E-value: 8.98e-11
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 56090598   46 SIDLQKKQNGIGILTLNNSNKMNAFSGAMMLQLLERVIELENWTEGKGLIVHGAKNTFCSGSDLNAVKAL------STPE 119
Cdd:PRK05674   6 TIELIRDPRGFATLWLSRADKNNAFNAQMIRELILALDQVQSDASLRFLLLRGRGRHFSAGADLAWMQQSadldynTNLD 85

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 56090598  120 NGVALSMFMQNtltrFMRLPLISVALVQGWAMGGGAELTTACDFRLMTEESVIRFVHKEMGIVPSWgGASRLVEIIGSRQ 199
Cdd:PRK05674  86 DARELAELMYN----LYRLKIPTLAVVQGAAFGGALGLISCCDMAIGADDAQFCLSEVRIGLAPAV-ISPFVVKAIGERA 160

                        170       180       190       200       210
                 ....*....|....*....|....*....|....*....|....*....|....*..
gi 56090598  200 ALKVLSGTFKLDSKEALRIGLADEVLqPSDEATAleQAQEWLEQFVSGPAQVIRGLK 256
Cdd:PRK05674 161 ARRYALTAERFDGRRARELGLLAESY-PAAELEA--QVEAWIANLLLNSPQALRASK 214
PRK06072 PRK06072
enoyl-CoA hydratase; Provisional
 53-274 1.06e-10

enoyl-CoA hydratase; Provisional


Pssm-ID: 168377 [Multi-domain]  Cd Length: 248  Bit Score: 60.56  E-value: 1.06e-10
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 56090598   53 QNGIGILTLNNSNKMNAFSGAMMLQLLERVIELENWTEGKGLIVHGAKNTFCSGSDLNAVkalsTPEngvaLSMFMQNT- 131
Cdd:PRK06072   7 REGYAIVTMSRPDKLNALNLEMRNEFISKLKQINADPKIRVVIVTGEGRAFCVGADLSEF----APD----FAIDLRETf 78

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 56090598  132 --LTRFMRLP-LISVALVQGWAMGGGAELTTACDFRLMTEESviRFV--HKEMGIVPSWGGASRLVEIIGSR-QALKVLS 205
Cdd:PRK06072  79 ypIIREIRFSdKIYISAINGVTAGACIGIALSTDFKFASRDV--KFVtaFQRLGLASDTGVAYFLLKLTGQRfYEILVLG 156

                        170       180       190       200       210       220       230
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 56090598  206 GTFklDSKEALRIGLADEVLQPsdeataLEQAQEWLEQFVSGPAQVIRGLKKSVcsGRELY--LEEALQNE 274
Cdd:PRK06072 157 GEF--TAEEAERWGLLKISEDP------LSDAEEMANRISNGPFQSYIAAKRMI--NLVLYndLEEFLEYE 217
PRK06495 PRK06495
enoyl-CoA hydratase/isomerase family protein;
55-239 4.32e-09

enoyl-CoA hydratase/isomerase family protein;


Pssm-ID: 168580 [Multi-domain]  Cd Length: 257  Bit Score: 56.24  E-value: 4.32e-09
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 56090598   55 GIGILTLNNSnKMNAFSGAMMLQLLERVIELENWTEGKGLIVHGAKNTFCSGSDLNAVKALSTPENgvalSMFMQNTLTR 134
Cdd:PRK06495  13 HVAVVTLDNP-PVNALSRELRDELIAVFDEISERPDVRVVVLTGAGKVFCAGADLKGRPDVIKGPG----DLRAHNRRTR 87

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 56090598  135 FMRLPLIS-----VALVQGWAMGGGAELTTACDFRLMTEESVIRFVHKEMGIVpswGGASRLVEIIG-SRQALKVLSGtF 208
Cdd:PRK06495  88 ECFHAIREcakpvIAAVNGPALGAGLGLVASCDIIVASENAVFGLPEIDVGLA---GGGKHAMRLFGhSLTRRMMLTG-Y 163

                        170       180       190
                 ....*....|....*....|....*....|...
gi 56090598  209 KLDSKEALRIGLADEVLqPSDE--ATALEQAQE 239
Cdd:PRK06495 164 RVPAAELYRRGVIEACL-PPEElmPEAMEIARE 195
PLN02921 PLN02921
naphthoate synthase
 55-258 5.73e-09

naphthoate synthase


Pssm-ID: 178509 [Multi-domain]  Cd Length: 327  Bit Score: 56.33  E-value: 5.73e-09
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 56090598   55 GIGILTLNNSNKMNAFSgAMMLQLLERVIELENWTEGKGLIVHGAKNT--FCSGSDlnavKALSTPENGVALSMFMQ-NT 131
Cdd:PLN02921  76 GIAKITINRPERRNAFR-PRTVKELQRAFNDARDDSSVGVIILTGKGTkaFCSGGD----QAVRGKDGYVGPDDAGRlNV 150

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 56090598  132 LTRFM---RLPLISVALVQGWAMGGGAELTTACDFRLMTEESVIRFVHKEMGIVPSWGGASRLVEIIGSRQALKVLSGTF 208
Cdd:PLN02921 151 LDLQIqirRLPKPVIAMVAGYAVGGGHILHMVCDLTIAADNAVFGQTGPKVGSFDAGYGSSIMARLVGQKKAREMWFLAR 230

                        170       180       190       200       210
                 ....*....|....*....|....*....|....*....|....*....|.
gi 56090598  209 KLDSKEALRIGLADEVLqPSDEataLEQAQ-EWLEQFVSGPAQVIRGLKKS 258
Cdd:PLN02921 231 FYTASEALKMGLVNTVV-PLDE---LEGETvKWCREILRNSPTAIRVLKSA 277
PRK11423 PRK11423
methylmalonyl-CoA decarboxylase; Provisional
 53-237 2.08e-08

methylmalonyl-CoA decarboxylase; Provisional


Pssm-ID: 236908 [Multi-domain]  Cd Length: 261  Bit Score: 53.88  E-value: 2.08e-08
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 56090598   53 QNGIGILTLNNSNKMNAFSGAMMLQLLERVIELENwTEGKGLIVHGAKNT--FCSGSDlnaVKALSTP-ENGVALSMFMQ 129
Cdd:PRK11423  11 INKIATITFNNPAKRNALSKVLIDDLMQALSDLNR-PEIRVVILRAPSGSkvWSAGHD---IHELPSGgRDPLSYDDPLR 86

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 56090598  130 NTLTRFMRLPLISVALVQGWAMGGGAELTTACDFRLMTEESVIRFVHKEMGIVPSWGGASRLVEIIGSRQALKVLSGTFK 209
Cdd:PRK11423  87 QILRMIQKFPKPVIAMVEGSVWGGAFELIMSCDLIIAASTSTFAMTPANLGVPYNLSGILNFTNDAGFHIVKEMFFTASP 166

                        170       180
                 ....*....|....*....|....*....
gi 56090598  210 LDSKEALRIGLADEVLQPSD-EATALEQA 237
Cdd:PRK11423 167 ITAQRALAVGILNHVVEVEElEDFTLQMA 195
PRK08321 PRK08321
1,4-dihydroxy-2-naphthoyl-CoA synthase;
132-256 2.70e-08

1,4-dihydroxy-2-naphthoyl-CoA synthase;


Pssm-ID: 181386  Cd Length: 302  Bit Score: 53.87  E-value: 2.70e-08
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 56090598  132 LTRFMrlPLISVALVQGWAMGGGAELTTACDFRLMTEE-SVIRFVHKEMGIVPSWGGASRLVEIIGSRQALKVLSGTFKL 210
Cdd:PRK08321 130 LIRFM--PKVVIAVVPGWAAGGGHSLHVVCDLTLASREhARFKQTDADVGSFDGGYGSAYLARQVGQKFAREIFFLGRTY 207

                         90       100       110       120
                 ....*....|....*....|....*....|....*....|....*..
gi 56090598  211 DSKEALRIGLADEVLQPSD-EATALeqaqEWLEQFVSGPAQVIRGLK 256
Cdd:PRK08321 208 SAEEAHDMGAVNAVVPHAElETEAL----EWAREINGKSPTAMRMLK 250
PRK08139 PRK08139
enoyl-CoA hydratase; Validated
 54-272 1.17e-07

enoyl-CoA hydratase; Validated


Pssm-ID: 181249  Cd Length: 266  Bit Score: 51.87  E-value: 1.17e-07
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 56090598   54 NGIGILTLNNSNKMNAFSGAMMLQLLERVIELENWTEGKGLIVHGAKNTFCSGSDLNAVKALSTPENGVAL----SMFMQ 129
Cdd:PRK08139  19 DGVATLTLNRPQAFNALSEAMLAALQAALDAIAADPSVRVVVLAAAGKAFCAGHDLKEMRAARGLAYFRALfarcSRVMQ 98

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 56090598  130 nTLTRfMRLPLIsvALVQGWAMGGGAELTTACDFRLMTEESviRF----VHkeMGIVPSWGGA--SRLVeiiGSRQALKV 203
Cdd:PRK08139  99 -AIVA-LPQPVI--ARVHGIATAAGCQLVASCDLAVAADTA--RFavpgVN--IGLFCSTPMValSRNV---PRKQAMEM 167

                        170       180       190       200       210       220       230
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 56090598  204 L-SGTFkLDSKEALRIGLADEVLQPSDEATAleqAQEWLEQFVSGPAQVIRGLKKSVCSGRELYLEEALQ 272
Cdd:PRK08139 168 LlTGEF-IDAATAREWGLVNRVVPADALDAA---VARLAAVIAAKSPAAVRIGKEAFYRQAEMPLADAYA 233
PRK07827 PRK07827
enoyl-CoA hydratase family protein;
55-233 1.24e-07

enoyl-CoA hydratase family protein;


Pssm-ID: 236109 [Multi-domain]  Cd Length: 260  Bit Score: 51.61  E-value: 1.24e-07
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 56090598   55 GIGILTLNNSNKMNAFSGAMMLQLLERVIELENWTEGKGLIVHGAKNTFCSGSDLNAVKALSTPENGVALSMF--MQNTL 132
Cdd:PRK07827  15 GVATLTLDSPHNRNALSARLVAQLHDGLRAAAADPAVRAVVLTHTGGTFCAGADLSEAGGGGGDPYDAAVARAreMTALL 94

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 56090598  133 TRFMRLPLISVALVQGWAMGGGAELTTACDFRLMTEESVIRFVHKEMGIVPSWGGASRLVEIIGSRQALKVLSGTfKLDS 212
Cdd:PRK07827  95 RAIVELPKPVIAAIDGHVRAGGFGLVGACDIVVAGPESTFALTEARIGVAPAIISLTLLPRLSPRAAARYYLTGE-KFGA 173

                        170       180
                 ....*....|....*....|.
gi 56090598  213 KEALRIGLADEVLQPSDEATA 233
Cdd:PRK07827 174 AEAARIGLVTAAADDVDAAVA 194
PLN02874 PLN02874
3-hydroxyisobutyryl-CoA hydrolase-like protein
 49-236 3.35e-07

3-hydroxyisobutyryl-CoA hydrolase-like protein


Pssm-ID: 178462 [Multi-domain]  Cd Length: 379  Bit Score: 50.95  E-value: 3.35e-07
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 56090598   49 LQKKQNGIGILTLNNSNKMNAFSGAMMLQLLERvieLENWTE---GKGLIVHGAKNTFCSGSDLNAVKALSTPENG---V 122
Cdd:PLN02874  14 LGEEKGRVRVITLNRPRQLNVISLSVVSLLAEF---LEQWEKddsVELIIIKGAGRAFSAGGDLKMFYDGRESDDScleV 90

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 56090598  123 ALSMFMQNTLTRFMRLPLisVALVQGWAMGGGAELTTACDFRLMTEESVIRFVHKEMGIVPSWGGA---SRLVEIIGSRQ 199
Cdd:PLN02874  91 VYRMYWLCYHIHTYKKTQ--VALVHGLVMGGGAGLMVPMKFRVVTEKTVFATPEASVGFHTDCGFSyilSRLPGHLGEYL 168

                        170       180       190
                 ....*....|....*....|....*....|....*..
gi 56090598  200 AlkvLSGTfKLDSKEALRIGLADEVLqPSDEATALEQ 236
Cdd:PLN02874 169 A---LTGA-RLNGKEMVACGLATHFV-PSEKLPELEK 200
PRK08272 PRK08272
crotonase/enoyl-CoA hydratase family protein;
53-247 4.82e-07

crotonase/enoyl-CoA hydratase family protein;


Pssm-ID: 236213  Cd Length: 302  Bit Score: 50.43  E-value: 4.82e-07
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 56090598   53 QNGIGILTLNNSNKMNAFSGAMMLQLLERVIELENWTEGKGLIVHGAKNTFCSGSDLNA-----------------VKAL 115
Cdd:PRK08272  17 TGRIARITLNRPEKGNAITADTPLELRAAVERADLDPGVHVILVSGAGKGFCAGYDLSAyaegsssgggggaypgkRQAV 96

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 56090598  116 STPENGVALSMFMQNTLTRF-------MRLPLISVALVQGWAMGGGAELTTACDFRLMTEESVIrfvhkemGIVPS--WG 186
Cdd:PRK08272  97 NHLPDDPWDPMIDYQMMSRFvrgfmslWHAHKPTVAKVHGYCVAGGTDIALHCDQVIAADDAKI-------GYPPTrvWG 169

                        170       180       190       200       210       220
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 56090598  187 G------ASRLveiiGSRQALKVLSGTFKLDSKEALRIGLADEVLQPSDeataLEQAQEWLEQFVSG 247
Cdd:PRK08272 170 VpatgmwAYRL----GPQRAKRLLFTGDCITGAQAAEWGLAVEAVPPEE----LDERTERLVERIAA 228
PLN02157 PLN02157
3-hydroxyisobutyryl-CoA hydrolase-like protein
 61-236 9.88e-07

3-hydroxyisobutyryl-CoA hydrolase-like protein


Pssm-ID: 177817 [Multi-domain]  Cd Length: 401  Bit Score: 49.68  E-value: 9.88e-07
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 56090598   61 LNNSNKMNAFSGAMMLQLLERvieLENWTEGKGL---IVHGAKNTFCSGSDLNAVKALSTPENGVALSMFMqNTLTRFMR 137
Cdd:PLN02157  52 LNRPPALNALTTHMGYRLQKL---YKNWEEDPNIgfvMMKGSGRAFCAGGDIVSLYHLRKRGSPDAIREFF-SSLYSFIY 127

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 56090598  138 L------PliSVALVQGWAMGGGAELTTACDFRLMTEESVIRFVHKEMGIVPSWGGASRLVEIIGSRQALKVLSGtFKLD 211
Cdd:PLN02157 128 LlgtylkP--HVAILNGVTMGGGTGVSIPGTFRVATDRTIFATPETIIGFHPDAGASFNLSHLPGRLGEYLGLTG-LKLS 204

                        170       180
                 ....*....|....*....|....*
gi 56090598  212 SKEALRIGLADEVLQpSDEATALEQ 236
Cdd:PLN02157 205 GAEMLACGLATHYIR-SEEIPVMEE 228
PRK08788 PRK08788
enoyl-CoA hydratase; Validated
 131-236 1.05e-06

enoyl-CoA hydratase; Validated


Pssm-ID: 236338  Cd Length: 287  Bit Score: 49.14  E-value: 1.05e-06
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 56090598  131 TLTRFMRLPLISVALVQGWAMGGGAELTTACDFrLMTEESViRFVHKEM--GIVPSWGGASRLVEIIGSRQALK-VLSGt 207
Cdd:PRK08788 113 AFHRGFGAGAISIALVQGDALGGGFEAALSHHT-IIAERGA-KMGFPEIlfNLFPGMGAYSFLARRVGPKLAEElILSG- 189

                         90       100       110
                 ....*....|....*....|....*....|
gi 56090598  208 fKL-DSKEALRIGLADEVLQPSDEATALEQ 236
Cdd:PRK08788 190 -KLyTAEELHDMGLVDVLVEDGQGEAAVRT 218
PRK07396 PRK07396
dihydroxynaphthoic acid synthetase; Validated
 49-242 1.36e-06

dihydroxynaphthoic acid synthetase; Validated


Pssm-ID: 180958 [Multi-domain]  Cd Length: 273  Bit Score: 48.74  E-value: 1.36e-06
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 56090598   49 LQKKQNGIGILTLNNSNKMNAFSGAMMLQLLERVIELENWTEGKGLIVHGA-KNTFCSGSDLNaVKALS--TPENGVA-L 124
Cdd:PRK07396  16 LYKSADGIAKITINRPEVRNAFRPKTVKEMIDAFADARDDDNIGVIILTGAgDKAFCSGGDQK-VRGYGgyVDDDGVPrL 94

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 56090598  125 SMFmqnTLTRFMR-LPLISVALVQGWAMGGGAELTTACDFRLMTEESVIRFVHKEMGIVPSWGGASRLVEIIGSRQALKV 203
Cdd:PRK07396  95 NVL---DLQRLIRtCPKPVIAMVAGYAIGGGHVLHLVCDLTIAADNAIFGQTGPKVGSFDGGYGASYLARIVGQKKAREI 171

                        170       180       190       200
                 ....*....|....*....|....*....|....*....|.
gi 56090598  204 LSGTFKLDSKEALRIGLADEVLqPSD--EATALEQAQEWLE 242
Cdd:PRK07396 172 WFLCRQYDAQEALDMGLVNTVV-PLAdlEKETVRWCREMLQ 211
PRK06023 PRK06023
crotonase/enoyl-CoA hydratase family protein;
55-270 4.75e-06

crotonase/enoyl-CoA hydratase family protein;


Pssm-ID: 168351  Cd Length: 251  Bit Score: 47.09  E-value: 4.75e-06
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 56090598   55 GIGILTLNNSNKMNAFSGAMMLQLLERVIELENWTEGKGLIVHGAKNTFCSGSDLN--AVKALSTPENGVALSMFMQnTL 132
Cdd:PRK06023  15 GVQVIRFNRPEKKNAITRAMYATMAKALKAADADDAIRAHVFLGTEGCFSAGNDMQdfLAAAMGGTSFGSEILDFLI-AL 93

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 56090598  133 TRFMRlPLISValVQGWAMGGGAELTTACDFRLMTEESVIRFVHKEMGIVPSwgGASRLV--EIIGSRQALKVLSGTFKL 210
Cdd:PRK06023  94 AEAEK-PIVSG--VDGLAIGIGTTIHLHCDLTFASPRSLFRTPFVDLALVPE--AGSSLLapRLMGHQRAFALLALGEGF 168

                        170       180       190       200       210       220
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 56090598  211 DSKEALRIGLADEVLQPSD-EATALEQAqewlEQFVSGPAQVIRGLKKSVCSGRELYL----EEA 270
Cdd:PRK06023 169 SAEAAQEAGLIWKIVDEEAvEAETLKAA----EELAAKPPQALQIARDLMRGPREDILaridEEA 229
PRK07260 PRK07260
enoyl-CoA hydratase; Provisional
 53-274 1.03e-05

enoyl-CoA hydratase; Provisional


Pssm-ID: 180910 [Multi-domain]  Cd Length: 255  Bit Score: 45.89  E-value: 1.03e-05
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 56090598   53 QNGIGILTLNNSNKMNAFSGAMMLQLLERVIELENWTEGKGLIVHGAKNTFCSGSDLNAVKALSTPENGVALSMFMQ--N 130
Cdd:PRK07260   9 EDDLATLTLNRPEVSNGFNIPMCQEILEALRLAEEDPSVRFLLINANGKVFSVGGDLVEMKRAVDEDDVQSLVKIAElvN 88

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 56090598  131 TLTRFM-RLPLISVALVQGWAMGGGAELTTACDFRLMTEESviRFVHK--EMGIVPSWGGASRLVEIIGSRQALKVLSGT 207
Cdd:PRK07260  89 EISFAIkQLPKPVIMCVDGAVAGAAANMAVAADFCIASTKT--KFIQAfvGVGLAPDAGGLFLLTRAIGLNRATHLAMTG 166

                        170       180       190       200       210       220       230
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 56090598  208 FKLDSKEALRIGLADEVLQPSDEATALEQAqewLEQFVSGPAQVIRGLK----KSVCSGRELY--LEEALQNE 274
Cdd:PRK07260 167 EALTAEKALEYGFVYRVAESEKLEKTCEQL---LKKLRRGSSNSYAAIKslvwESFFKGWEDYakLELALQES 236
MenB COG0447
1,4-Dihydroxy-2-naphthoyl-CoA synthase [Coenzyme transport and metabolism]; 1, ...
 132-256 1.06e-05

1,4-Dihydroxy-2-naphthoyl-CoA synthase [Coenzyme transport and metabolism]; 1,4-Dihydroxy-2-naphthoyl-CoA synthase is part of the Pathway/BioSystem: Menaquinone biosynthesis


Pssm-ID: 440216  Cd Length: 281  Bit Score: 45.97  E-value: 1.06e-05
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 56090598 132 LTRFMRLPLIsvALVQGWAMGGGAELTTACDFRLMTEESviRFvhKEMGivPSWG------GASRLVEIIGSRQALKVLS 205
Cdd:COG0447 112 LIRFMPKPVI--AMVAGWAIGGGHVLHVVCDLTIASENA--RF--GQTG--PDVGsfdagyGSAYLARQVGQKKAREIWF 183

                        90       100       110       120       130
                ....*....|....*....|....*....|....*....|....*....|...
gi 56090598 206 GTFKLDSKEALRIGLADEVLqPSD--EATALEQAQEWLEQfvsGPaQVIRGLK 256
Cdd:COG0447 184 LCRQYSAQEALEMGLVNKVV-PHAelEEEAVEWAREILEK---SP-TAIRMLK 231
PRK05617 PRK05617
3-hydroxyisobutyryl-CoA hydrolase; Provisional
 52-237 3.09e-05

3-hydroxyisobutyryl-CoA hydrolase; Provisional


Pssm-ID: 235533 [Multi-domain]  Cd Length: 342  Bit Score: 44.81  E-value: 3.09e-05
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 56090598   52 KQNGIGILTLNNSNKMNAFSGAMMLQLLERVIELENWTEGKGLIVHGA-KNTFCSGSDLNAVKALSTPENGVALSMF--- 127
Cdd:PRK05617   9 VEGGVGVITLNRPKALNALSLEMIRAIDAALDAWEDDDAVAAVVIEGAgERGFCAGGDIRALYEAARAGDPLAADRFfre 88

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 56090598  128 ---MQNTLTRFmrlPLISVALVQGWAMGGGAELTTACDFRLMTEESviRFVHKEMGI--VPSWGGA---SRLVEIIGSRQ 199
Cdd:PRK05617  89 eyrLNALIARY---PKPYIALMDGIVMGGGVGISAHGSHRIVTERT--KMAMPETGIgfFPDVGGTyflSRAPGALGTYL 163

                        170       180       190
                 ....*....|....*....|....*....|....*...
gi 56090598  200 AlkvLSGTfKLDSKEALRIGLADEVLqPSDEATALEQA 237
Cdd:PRK05617 164 A---LTGA-RISAADALYAGLADHFV-PSADLPALLDA 196
PRK07112 PRK07112
enoyl-CoA hydratase/isomerase;
51-229 4.95e-05

enoyl-CoA hydratase/isomerase;


Pssm-ID: 235938  Cd Length: 255  Bit Score: 43.90  E-value: 4.95e-05
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 56090598   51 KKQNGIGILTLNNSNKMNAFSGAMMLQLLERVIELENwtEGKGLIVHGAKNTFCSGSDLNAVKALSTPENGVALSM-FMQ 129
Cdd:PRK07112   9 RQQGDVCFLQLHRPEAQNTINDRLIAECMDVLDRCEH--AATIVVLEGLPEVFCFGADFSAIAEKPDAGRADLIDAePLY 86

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 56090598  130 NTLTRFMRLPLISVALVQGWAMGGGAELTTACDFRLMTEESviRFVHKEM--GIVPswggASR---LVEIIGSRQALKVL 204
Cdd:PRK07112  87 DLWHRLATGPYVTIAHVRGKVNAGGIGFVAASDIVIADETA--PFSLSELlfGLIP----ACVlpfLIRRIGTQKAHYMT 160

                        170       180
                 ....*....|....*....|....*
gi 56090598  205 SGTFKLDSKEALRIGLADEVLQPSD 229
Cdd:PRK07112 161 LMTQPVTAQQAFSWGLVDAYGANSD 185
PLN02267 PLN02267
enoyl-CoA hydratase/isomerase family protein
 49-233 5.37e-04

enoyl-CoA hydratase/isomerase family protein


Pssm-ID: 215151  Cd Length: 239  Bit Score: 40.47  E-value: 5.37e-04
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 56090598   49 LQKKQNgIGILTLNNSN--KMNAFSGAMMLQLLERVieLENWTEGKGLIVHGAKNTFCSGSDLN-AVKALSTPENGVALS 125
Cdd:PLN02267   4 LEKRGN-LFILTLTGDGehRLNPTLIDSIRSALRQV--KSQATPGSVLITTAEGKFFSNGFDLAwAQAAGSAPSRLHLMV 80

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 56090598  126 MFMQNTLTRFMRLPLISVALVQGWAMGGGAELTTACDFRLM-TEESVIRFVHKEMG-IVPSWGGASrLVEIIGSRQALK- 202
Cdd:PLN02267  81 AKLRPLVADLISLPMPTIAAVTGHASAAGFILALSHDYVLMrKDRGVLYMSEVDIGlPLPDYFMAL-LRAKIGSPAARRd 159

                        170       180       190
                 ....*....|....*....|....*....|..
gi 56090598  203 -VLSGTfKLDSKEALRIGLADEVlQPSDEATA 233
Cdd:PLN02267 160 vLLRAA-KLTAEEAVEMGIVDSA-HDSAEETV 189
PRK08290 PRK08290
enoyl-CoA hydratase; Provisional
 53-259 6.24e-04

enoyl-CoA hydratase; Provisional


Pssm-ID: 236220 [Multi-domain]  Cd Length: 288  Bit Score: 40.71  E-value: 6.24e-04
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 56090598   53 QNGIGILTLNNSNKMNAFSGAMMLQLLE-----------RVIEL----ENWTEGKGLIVHGAKNTFCSGSDLNAVKAL-- 115
Cdd:PRK08290  11 AGRIARITLNRPEARNAQNRQMLYELDAafrraeaddavRVIVLagagKHFSAGHDLGSGTPGRDRDPGPDQHPTLWWdg 90

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 56090598  116 ---STPENGVALSM--FMQNTLtRFMRLPLISVALVQGWAMGGGAELTTACDFRLMTEESVIRFVHKEMGIvpswGGasr 190
Cdd:PRK08290  91 atkPGVEQRYAREWevYLGMCR-RWRDLPKPTIAQVQGACIAGGLMLAWVCDLIVASDDAFFSDPVVRMGI----PG--- 162

                        170       180       190       200       210       220       230
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 56090598  191 lVEI------IGSRQALKVLSGTFKLDSKEALRIGLADEVLqPSDEataLEQAQ-EWLEQFVSGPAQVIRGLKKSV 259
Cdd:PRK08290 163 -VEYfahpweLGPRKAKELLFTGDRLTADEAHRLGMVNRVV-PRDE---LEAETlELARRIAAMPPFGLRLTKRAV 233
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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