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Conserved domains on  [gi|62078739|ref|NP_001014027|]
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T-cell leukemia translocation-altered gene protein homolog isoform 2 [Rattus norvegicus]

Protein Classification

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
T_cell_tran_alt super family cl20996
T-cell leukemia translocation-altered; This family of proteins is required for ...
 15-106 3.36e-39

T-cell leukemia translocation-altered; This family of proteins is required for osteoclastogenesis.


The actual alignment was detected with superfamily member pfam15128:

Pssm-ID: 464518  Cd Length: 92  Bit Score: 125.70  E-value: 3.36e-39
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 62078739    15 ATVLGALGTLGSEFLREWETQDMRVTLFKLLLLWLVLSLLGIQLAWGFYGNTVTGLYHRPGLGGQNGSTPDGSTHFPSWE 94
Cdd:pfam15128   1 SRVLDSLLSFLSEFVDDWLANDMRVAIFKLLLGWLVLSLLAIHLAWKVYGNTVNDMYYRQGTGGQNGGTPDAAPHFSSWE 80

                          90
                  ....*....|..
gi 62078739    95 MAANEALKTHRE 106
Cdd:pfam15128  81 SAAGDPLKTHRE 92
 
Name Accession Description Interval E-value
T_cell_tran_alt pfam15128
T-cell leukemia translocation-altered; This family of proteins is required for ...
 15-106 3.36e-39

T-cell leukemia translocation-altered; This family of proteins is required for osteoclastogenesis.


Pssm-ID: 464518  Cd Length: 92  Bit Score: 125.70  E-value: 3.36e-39
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 62078739    15 ATVLGALGTLGSEFLREWETQDMRVTLFKLLLLWLVLSLLGIQLAWGFYGNTVTGLYHRPGLGGQNGSTPDGSTHFPSWE 94
Cdd:pfam15128   1 SRVLDSLLSFLSEFVDDWLANDMRVAIFKLLLGWLVLSLLAIHLAWKVYGNTVNDMYYRQGTGGQNGGTPDAAPHFSSWE 80

                          90
                  ....*....|..
gi 62078739    95 MAANEALKTHRE 106
Cdd:pfam15128  81 SAAGDPLKTHRE 92
 
Name Accession Description Interval E-value
T_cell_tran_alt pfam15128
T-cell leukemia translocation-altered; This family of proteins is required for ...
 15-106 3.36e-39

T-cell leukemia translocation-altered; This family of proteins is required for osteoclastogenesis.


Pssm-ID: 464518  Cd Length: 92  Bit Score: 125.70  E-value: 3.36e-39
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 62078739    15 ATVLGALGTLGSEFLREWETQDMRVTLFKLLLLWLVLSLLGIQLAWGFYGNTVTGLYHRPGLGGQNGSTPDGSTHFPSWE 94
Cdd:pfam15128   1 SRVLDSLLSFLSEFVDDWLANDMRVAIFKLLLGWLVLSLLAIHLAWKVYGNTVNDMYYRQGTGGQNGGTPDAAPHFSSWE 80

                          90
                  ....*....|..
gi 62078739    95 MAANEALKTHRE 106
Cdd:pfam15128  81 SAAGDPLKTHRE 92
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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