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Conserved domains on  [gi|1939872715|ref|NP_001017503|]
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transcriptional regulator protein Pur-beta [Rattus norvegicus]

Protein Classification

Pur family transcription activator( domain architecture ID 12058637)

Pur family transcription activator such as Pur-alpha (PurA), Pur-beta (PurB), and Pur-gamma (PurG), which bind preferentially to the single strand of the purine-rich element termed PUR, which is present at origins of replication and in gene flanking regions in a variety of eukaryotes from yeasts through humans

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
PurA pfam04845
PurA ssDNA and RNA-binding protein; This family represents most of the length of the protein.
 36-284 2.58e-114

PurA ssDNA and RNA-binding protein; This family represents most of the length of the protein.


:

Pssm-ID: 282672 [Multi-domain]  Cd Length: 219  Bit Score: 329.48  E-value: 2.58e-114
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1939872715  36 TQELASKRLDIQNKRFYLDVKQNAKGRFLKIAEVGAGGSKSRLTLSMAVAAEFRDSLGDFIEHYAQLGPSSPEQLaagAE 115
Cdd:pfam04845   1 EQELASKRLDIQNKRFYLDVKQNTRGRFIKIAEVGAGGRKSRITLSMSVAAEFKDELSKFSDHYAQLGPSNGEHL---PE 77

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1939872715 116 EGggpRRALKSEFLVRENRKYYLDLKENQRGRFLRIRQTVNRggggfgggpgPGGLQSGQTIALPAQGLIEFRDALAKLI 195
Cdd:pfam04845  78 DG---SSLLKSETLVRDNRKYYLDLKENQRGRFLRIAQTPMR----------GNPRGQRQQIALPAQGMIEFRDALTDLI 144

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1939872715 196 DDYGGEDDElaggpgggaggpggGLYGELPEGTSITVDSKRFFFDVGCNKYGVFLRVSEVKPSYRNAITVPFKAWGKFGG 275
Cdd:pfam04845 145 EDYGEGDEN--------------DIPQELPEGTSLTVDNKRFYFDVGSNKRGVFLRISEVKPNYRNSITVPEKAWTRFRD 210


                  ....*....
gi 1939872715 276 AFCRYADEM 284
Cdd:pfam04845 211 IFDKYIEKM 219
 
Name Accession Description Interval E-value
PurA pfam04845
PurA ssDNA and RNA-binding protein; This family represents most of the length of the protein.
 36-284 2.58e-114

PurA ssDNA and RNA-binding protein; This family represents most of the length of the protein.


Pssm-ID: 282672 [Multi-domain]  Cd Length: 219  Bit Score: 329.48  E-value: 2.58e-114
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1939872715  36 TQELASKRLDIQNKRFYLDVKQNAKGRFLKIAEVGAGGSKSRLTLSMAVAAEFRDSLGDFIEHYAQLGPSSPEQLaagAE 115
Cdd:pfam04845   1 EQELASKRLDIQNKRFYLDVKQNTRGRFIKIAEVGAGGRKSRITLSMSVAAEFKDELSKFSDHYAQLGPSNGEHL---PE 77

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1939872715 116 EGggpRRALKSEFLVRENRKYYLDLKENQRGRFLRIRQTVNRggggfgggpgPGGLQSGQTIALPAQGLIEFRDALAKLI 195
Cdd:pfam04845  78 DG---SSLLKSETLVRDNRKYYLDLKENQRGRFLRIAQTPMR----------GNPRGQRQQIALPAQGMIEFRDALTDLI 144

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1939872715 196 DDYGGEDDElaggpgggaggpggGLYGELPEGTSITVDSKRFFFDVGCNKYGVFLRVSEVKPSYRNAITVPFKAWGKFGG 275
Cdd:pfam04845 145 EDYGEGDEN--------------DIPQELPEGTSLTVDNKRFYFDVGSNKRGVFLRISEVKPNYRNSITVPEKAWTRFRD 210


                  ....*....
gi 1939872715 276 AFCRYADEM 284
Cdd:pfam04845 211 IFDKYIEKM 219
PUR smart00712
DNA/RNA-binding repeats in PUR-alpha/beta/gamma and in hypothetical proteins from spirochetes ...
 38-100 1.76e-25

DNA/RNA-binding repeats in PUR-alpha/beta/gamma and in hypothetical proteins from spirochetes and the Bacteroides-Cytophaga-Flexibacter bacteria;


Pssm-ID: 197840 [Multi-domain]  Cd Length: 63  Bit Score: 96.52  E-value: 1.76e-25
                           10        20        30        40        50        60
                   ....*....|....*....|....*....|....*....|....*....|....*....|...
gi 1939872715   38 ELASKRLDIQNKRFYLDVKQNAKGRFLKIAEVGAGGSKSRLTLSMAVAAEFRDSLGDFIEHYA 100
Cdd:smart00712   1 ELASKKLTVENKRFYFDVKENRRGRFLRISEVKNNGGRSSITVPEQGAAEFRDALTKLIEKYG 63
 
Name Accession Description Interval E-value
PurA pfam04845
PurA ssDNA and RNA-binding protein; This family represents most of the length of the protein.
 36-284 2.58e-114

PurA ssDNA and RNA-binding protein; This family represents most of the length of the protein.


Pssm-ID: 282672 [Multi-domain]  Cd Length: 219  Bit Score: 329.48  E-value: 2.58e-114
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1939872715  36 TQELASKRLDIQNKRFYLDVKQNAKGRFLKIAEVGAGGSKSRLTLSMAVAAEFRDSLGDFIEHYAQLGPSSPEQLaagAE 115
Cdd:pfam04845   1 EQELASKRLDIQNKRFYLDVKQNTRGRFIKIAEVGAGGRKSRITLSMSVAAEFKDELSKFSDHYAQLGPSNGEHL---PE 77

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1939872715 116 EGggpRRALKSEFLVRENRKYYLDLKENQRGRFLRIRQTVNRggggfgggpgPGGLQSGQTIALPAQGLIEFRDALAKLI 195
Cdd:pfam04845  78 DG---SSLLKSETLVRDNRKYYLDLKENQRGRFLRIAQTPMR----------GNPRGQRQQIALPAQGMIEFRDALTDLI 144

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1939872715 196 DDYGGEDDElaggpgggaggpggGLYGELPEGTSITVDSKRFFFDVGCNKYGVFLRVSEVKPSYRNAITVPFKAWGKFGG 275
Cdd:pfam04845 145 EDYGEGDEN--------------DIPQELPEGTSLTVDNKRFYFDVGSNKRGVFLRISEVKPNYRNSITVPEKAWTRFRD 210


                  ....*....
gi 1939872715 276 AFCRYADEM 284
Cdd:pfam04845 211 IFDKYIEKM 219
PUR smart00712
DNA/RNA-binding repeats in PUR-alpha/beta/gamma and in hypothetical proteins from spirochetes ...
 38-100 1.76e-25

DNA/RNA-binding repeats in PUR-alpha/beta/gamma and in hypothetical proteins from spirochetes and the Bacteroides-Cytophaga-Flexibacter bacteria;


Pssm-ID: 197840 [Multi-domain]  Cd Length: 63  Bit Score: 96.52  E-value: 1.76e-25
                           10        20        30        40        50        60
                   ....*....|....*....|....*....|....*....|....*....|....*....|...
gi 1939872715   38 ELASKRLDIQNKRFYLDVKQNAKGRFLKIAEVGAGGSKSRLTLSMAVAAEFRDSLGDFIEHYA 100
Cdd:smart00712   1 ELASKKLTVENKRFYFDVKENRRGRFLRISEVKNNGGRSSITVPEQGAAEFRDALTKLIEKYG 63
PUR smart00712
DNA/RNA-binding repeats in PUR-alpha/beta/gamma and in hypothetical proteins from spirochetes ...
 124-199 8.65e-20

DNA/RNA-binding repeats in PUR-alpha/beta/gamma and in hypothetical proteins from spirochetes and the Bacteroides-Cytophaga-Flexibacter bacteria;


Pssm-ID: 197840 [Multi-domain]  Cd Length: 63  Bit Score: 81.50  E-value: 8.65e-20
                           10        20        30        40        50        60        70
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 1939872715  124 LKSEFLVRENRKYYLDLKENQRGRFLRIRQTVNRGgggfgggpgpgglqSGQTIALPAQGLIEFRDALAKLIDDYG 199
Cdd:smart00712   2 LASKKLTVENKRFYFDVKENRRGRFLRISEVKNNG--------------GRSSITVPEQGAAEFRDALTKLIEKYG 63
PUR smart00712
DNA/RNA-binding repeats in PUR-alpha/beta/gamma and in hypothetical proteins from spirochetes ...
 224-285 4.32e-18

DNA/RNA-binding repeats in PUR-alpha/beta/gamma and in hypothetical proteins from spirochetes and the Bacteroides-Cytophaga-Flexibacter bacteria;


Pssm-ID: 197840 [Multi-domain]  Cd Length: 63  Bit Score: 76.88  E-value: 4.32e-18
                           10        20        30        40        50        60
                   ....*....|....*....|....*....|....*....|....*....|....*....|...
gi 1939872715  224 LPEGTSITVDSKRFFFDVGCNKYGVFLRVSEVKPSY-RNAITVPFKAWGKFGGAFCRYADEMK 285
Cdd:smart00712   1 ELASKKLTVENKRFYFDVKENRRGRFLRISEVKNNGgRSSITVPEQGAAEFRDALTKLIEKYG 63
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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