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Conserved domains on  [gi|83816931|ref|NP_001033063|]
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junctophilin-2 [Rattus norvegicus]

Protein Classification

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
COG4642 COG4642
Uncharacterized conserved protein [Function unknown];
2-143 1.84e-26

Uncharacterized conserved protein [Function unknown];


:

Pssm-ID: 443680 [Multi-domain]  Cd Length: 271  Bit Score: 109.28  E-value: 1.84e-26
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 83816931   2 SGGRFDFDDGGAYCGGWEGGKAHGHGLCTGPKGqGEYSGSWNFG-FEVAGVYTWPSGNTFEGYWSQGKRHGLGIET-KGR 79
Cdd:COG4642 115 GGGVLEGDDGGGYGGGTADGGRGGGGIYTFPNG-DVYEGEFKNGkPHGQGTLTYADGDRYEGEFKNGKRHGQGTLTyANG 193

                        90       100       110       120       130       140
                ....*....|....*....|....*....|....*....|....*....|....*....|....
gi 83816931  80 WLYKGEWTHGFKGRYGIRQSTNsGAKYEGTWNNGLQDGYGTETYADGGTYQGQFTNGMRHGYGV 143
Cdd:COG4642 194 DVYEGEFKNGQRHGQGTYTYAD-GDRYEGEFKNGKRHGQGTLTYADGDRYEGEFKNGKRHGQGT 256
PLN03185 super family cl33654
phosphatidylinositol phosphate kinase; Provisional
 38-328 7.94e-11

phosphatidylinositol phosphate kinase; Provisional


The actual alignment was detected with superfamily member PLN03185:

Pssm-ID: 215619 [Multi-domain]  Cd Length: 765  Bit Score: 65.24  E-value: 7.94e-11
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 83816931   38 YSGSWNFGF-EVAGVYTWPSGNTFEGYWSQGKRHGLGietKGRWlykgewthgfkgrygirqstNSGAKYEGTWNNGLQD 116
Cdd:PLN03185  11 YSGSLLGNVpEGPGKYLWSDGCMYEGEWRRGMRHGNG---KISW--------------------PSGATYEGEFSGGYMH 67

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 83816931  117 GYGTETYADGGTYQGQFTNGMRHGYGvrqsvpygmavvvrsplrtslsslRSEHSNGTVAPDSpAADGptlplppVPRGg 196
Cdd:PLN03185  68 GSGTYTGTDGTTYKGRWRLNLKHGLG------------------------YQRYPNGDVFEGS-WIQG-------LQEG- 114

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 83816931  197 falsllataeaarpPGLFTrgallgrlrrsesrtslgsqrsrlsflkselssgasdaastgsLAEGAEgpddaaapfdad 276
Cdd:PLN03185 115 --------------PGKYT-------------------------------------------WANGNV------------ 125

                        250       260       270       280       290
                 ....*....|....*....|....*....|....*....|....*....|..
gi 83816931  277 idatttetYMGEWKNDKRSGFGVSERSSGLRYEGEWLDNLRHGYGRTTLPDG 328
Cdd:PLN03185 126 --------YLGDMKGGKMSGKGTLTWVSGDSYEGQWLDGMMHGFGVYTWSDG 169
PHA03247 super family cl33720
large tegument protein UL36; Provisional
 446-633 5.77e-07

large tegument protein UL36; Provisional


The actual alignment was detected with superfamily member PHA03247:

Pssm-ID: 223021 [Multi-domain]  Cd Length: 3151  Bit Score: 53.40  E-value: 5.77e-07
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 83816931   446 PRERGPGTGLPERPRESPQLHERETPQPEGGPPSPAGTPPQPKR---PRPGSSKDGLLSPgawNGEPGGEGSRPATPSDG 522
Cdd:PHA03247 2663 RPRRARRLGRAAQASSPPQRPRRRAARPTVGSLTSLADPPPPPPtpePAPHALVSATPLP---PGPAAARQASPALPAAP 2739

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 83816931   523 AGRRSPARPASEhMAIEALQPPPAPSREPEVALYRGYHSYAVRTGPPEPPPLEDEPEPEPEVPRSDSEPPSPVSAtvqee 602
Cdd:PHA03247 2740 APPAVPAGPATP-GGPARPARPPTTAGPPAPAPPAAPAAGPPRRLTRPAVASLSESRESLPSPWDPADPPAAVLA----- 2813

                         170       180       190
                  ....*....|....*....|....*....|...
gi 83816931   603 esPAPRSRVPAKPATLEPKP--IVPKAEPKAKA 633
Cdd:PHA03247 2814 --PAAALPPAASPAGPLPPPtsAQPTAPPPPPG 2844
 
Name Accession Description Interval E-value
COG4642 COG4642
Uncharacterized conserved protein [Function unknown];
2-143 1.84e-26

Uncharacterized conserved protein [Function unknown];


Pssm-ID: 443680 [Multi-domain]  Cd Length: 271  Bit Score: 109.28  E-value: 1.84e-26
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 83816931   2 SGGRFDFDDGGAYCGGWEGGKAHGHGLCTGPKGqGEYSGSWNFG-FEVAGVYTWPSGNTFEGYWSQGKRHGLGIET-KGR 79
Cdd:COG4642 115 GGGVLEGDDGGGYGGGTADGGRGGGGIYTFPNG-DVYEGEFKNGkPHGQGTLTYADGDRYEGEFKNGKRHGQGTLTyANG 193

                        90       100       110       120       130       140
                ....*....|....*....|....*....|....*....|....*....|....*....|....
gi 83816931  80 WLYKGEWTHGFKGRYGIRQSTNsGAKYEGTWNNGLQDGYGTETYADGGTYQGQFTNGMRHGYGV 143
Cdd:COG4642 194 DVYEGEFKNGQRHGQGTYTYAD-GDRYEGEFKNGKRHGQGTLTYADGDRYEGEFKNGKRHGQGT 256
PLN03185 PLN03185
phosphatidylinositol phosphate kinase; Provisional
 4-143 5.65e-20

phosphatidylinositol phosphate kinase; Provisional


Pssm-ID: 215619 [Multi-domain]  Cd Length: 765  Bit Score: 94.90  E-value: 5.65e-20
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 83816931    4 GRFDFDDGGAYCGGWEGGKAHGHGLCTGPKG---QGEYSGSWNFGFevaGVYTWPSGNTFEGYWSQGKRHGLGIETKGRW 80
Cdd:PLN03185  24 GKYLWSDGCMYEGEWRRGMRHGNGKISWPSGatyEGEFSGGYMHGS---GTYTGTDGTTYKGRWRLNLKHGLGYQRYPNG 100

                         90       100       110       120       130       140
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 83816931   81 -LYKGEWTHGFK---GRYgirqSTNSGAKYEGTWNNGLQDGYGTETYADGGTYQGQFTNGMRHGYGV 143
Cdd:PLN03185 101 dVFEGSWIQGLQegpGKY----TWANGNVYLGDMKGGKMSGKGTLTWVSGDSYEGQWLDGMMHGFGV 163
PLN03185 PLN03185
phosphatidylinositol phosphate kinase; Provisional
 38-328 7.94e-11

phosphatidylinositol phosphate kinase; Provisional


Pssm-ID: 215619 [Multi-domain]  Cd Length: 765  Bit Score: 65.24  E-value: 7.94e-11
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 83816931   38 YSGSWNFGF-EVAGVYTWPSGNTFEGYWSQGKRHGLGietKGRWlykgewthgfkgrygirqstNSGAKYEGTWNNGLQD 116
Cdd:PLN03185  11 YSGSLLGNVpEGPGKYLWSDGCMYEGEWRRGMRHGNG---KISW--------------------PSGATYEGEFSGGYMH 67

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 83816931  117 GYGTETYADGGTYQGQFTNGMRHGYGvrqsvpygmavvvrsplrtslsslRSEHSNGTVAPDSpAADGptlplppVPRGg 196
Cdd:PLN03185  68 GSGTYTGTDGTTYKGRWRLNLKHGLG------------------------YQRYPNGDVFEGS-WIQG-------LQEG- 114

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 83816931  197 falsllataeaarpPGLFTrgallgrlrrsesrtslgsqrsrlsflkselssgasdaastgsLAEGAEgpddaaapfdad 276
Cdd:PLN03185 115 --------------PGKYT-------------------------------------------WANGNV------------ 125

                        250       260       270       280       290
                 ....*....|....*....|....*....|....*....|....*....|..
gi 83816931  277 idatttetYMGEWKNDKRSGFGVSERSSGLRYEGEWLDNLRHGYGRTTLPDG 328
Cdd:PLN03185 126 --------YLGDMKGGKMSGKGTLTWVSGDSYEGQWLDGMMHGFGVYTWSDG 169
PHA03247 PHA03247
large tegument protein UL36; Provisional
 446-633 5.77e-07

large tegument protein UL36; Provisional


Pssm-ID: 223021 [Multi-domain]  Cd Length: 3151  Bit Score: 53.40  E-value: 5.77e-07
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 83816931   446 PRERGPGTGLPERPRESPQLHERETPQPEGGPPSPAGTPPQPKR---PRPGSSKDGLLSPgawNGEPGGEGSRPATPSDG 522
Cdd:PHA03247 2663 RPRRARRLGRAAQASSPPQRPRRRAARPTVGSLTSLADPPPPPPtpePAPHALVSATPLP---PGPAAARQASPALPAAP 2739

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 83816931   523 AGRRSPARPASEhMAIEALQPPPAPSREPEVALYRGYHSYAVRTGPPEPPPLEDEPEPEPEVPRSDSEPPSPVSAtvqee 602
Cdd:PHA03247 2740 APPAVPAGPATP-GGPARPARPPTTAGPPAPAPPAAPAAGPPRRLTRPAVASLSESRESLPSPWDPADPPAAVLA----- 2813

                         170       180       190
                  ....*....|....*....|....*....|...
gi 83816931   603 esPAPRSRVPAKPATLEPKP--IVPKAEPKAKA 633
Cdd:PHA03247 2814 --PAAALPPAASPAGPLPPPtsAQPTAPPPPPG 2844
MORN pfam02493
MORN repeat; The MORN (Membrane Occupation and Recognition Nexus) repeat is found in multiple ...
 106-128 1.44e-04

MORN repeat; The MORN (Membrane Occupation and Recognition Nexus) repeat is found in multiple copies in several proteins including junctophilins (See Takeshima et al. Mol. Cell 2000;6:11-22). A MORN-repeat protein has been identified in the parasite Toxoplasma gondiis a dynamic component of cell division apparatus in Toxoplasma gondii. It has been hypothesized to functions as a linker protein between certain membrane regions and the parasite's cytoskeleton.


Pssm-ID: 308220 [Multi-domain]  Cd Length: 23  Bit Score: 39.31  E-value: 1.44e-04
                          10        20
                  ....*....|....*....|...
gi 83816931   106 YEGTWNNGLQDGYGTETYADGGT 128
Cdd:pfam02493   1 YEGEWKNGKRHGKGVYTWPDGDR 23
MORN smart00698
Possible plasma membrane-binding motif in junctophilins, PIP-5-kinases and protein kinases;
307-327 3.88e-04

Possible plasma membrane-binding motif in junctophilins, PIP-5-kinases and protein kinases;


Pssm-ID: 197832 [Multi-domain]  Cd Length: 22  Bit Score: 38.09  E-value: 3.88e-04
                           10        20
                   ....*....|....*....|.
gi 83816931    307 RYEGEWLDNLRHGYGRTTLPD 327
Cdd:smart00698   2 RYEGEWRNGKRHGRGVYTYAN 22
MORN pfam02493
MORN repeat; The MORN (Membrane Occupation and Recognition Nexus) repeat is found in multiple ...
 308-330 5.05e-04

MORN repeat; The MORN (Membrane Occupation and Recognition Nexus) repeat is found in multiple copies in several proteins including junctophilins (See Takeshima et al. Mol. Cell 2000;6:11-22). A MORN-repeat protein has been identified in the parasite Toxoplasma gondiis a dynamic component of cell division apparatus in Toxoplasma gondii. It has been hypothesized to functions as a linker protein between certain membrane regions and the parasite's cytoskeleton.


Pssm-ID: 308220 [Multi-domain]  Cd Length: 23  Bit Score: 37.77  E-value: 5.05e-04
                          10        20
                  ....*....|....*....|...
gi 83816931   308 YEGEWLDNLRHGYGRTTLPDGHR 330
Cdd:pfam02493   1 YEGEWKNGKRHGKGVYTWPDGDR 23
DUF3827 pfam12877
Domain of unknown function (DUF3827); This family contains the Swiss:Q9HCM3 protein which has ...
 424-531 1.73e-03

Domain of unknown function (DUF3827); This family contains the Swiss:Q9HCM3 protein which has been found to be fused fused to BRAF gene in many cases of pilocytic astrocytomas. The fusion is due mainly to a tandem duplication of 2 Mb at 7q34. Although nothing is known about the function of Swiss:Q9HCM3 protein, the BRAF protein is a well characterized oncoprotein. It is a serine/threonine protein kinase which is implicated in MAP/ERK signalling, a critical pathway for the regulation of cell division, differentiation and secretion.


Pssm-ID: 463737  Cd Length: 677  Bit Score: 41.70  E-value: 1.73e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 83816931   424 GPEYQKRRLLQEileNSESLLEPRERGPgtgLPERPRESPQLHERETPQPEGGPPSPAGTPPQPKRPRPGSSKDGLLSPG 503
Cdd:pfam12877 316 GFDFAKQHLGQH---SKDDVPVIQEPAP---LPLPVKDATPSENGEVPTPKSKTSSKTSRGERRRGRISPSDGDSVGSDE 389

                          90       100
                  ....*....|....*....|....*....
gi 83816931   504 AWNGEPGGEGSRP-ATPSDGAGRRSPARP 531
Cdd:pfam12877 390 SSKRESGEESPRPaATPSDGKQHRKTNRP 418
MORN smart00698
Possible plasma membrane-binding motif in junctophilins, PIP-5-kinases and protein kinases;
104-125 4.32e-03

Possible plasma membrane-binding motif in junctophilins, PIP-5-kinases and protein kinases;


Pssm-ID: 197832 [Multi-domain]  Cd Length: 22  Bit Score: 35.01  E-value: 4.32e-03
                           10        20
                   ....*....|....*....|..
gi 83816931    104 AKYEGTWNNGLQDGYGTETYAD 125
Cdd:smart00698   1 DRYEGEWRNGKRHGRGVYTYAN 22
 
Name Accession Description Interval E-value
COG4642 COG4642
Uncharacterized conserved protein [Function unknown];
2-143 1.84e-26

Uncharacterized conserved protein [Function unknown];


Pssm-ID: 443680 [Multi-domain]  Cd Length: 271  Bit Score: 109.28  E-value: 1.84e-26
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 83816931   2 SGGRFDFDDGGAYCGGWEGGKAHGHGLCTGPKGqGEYSGSWNFG-FEVAGVYTWPSGNTFEGYWSQGKRHGLGIET-KGR 79
Cdd:COG4642 115 GGGVLEGDDGGGYGGGTADGGRGGGGIYTFPNG-DVYEGEFKNGkPHGQGTLTYADGDRYEGEFKNGKRHGQGTLTyANG 193

                        90       100       110       120       130       140
                ....*....|....*....|....*....|....*....|....*....|....*....|....
gi 83816931  80 WLYKGEWTHGFKGRYGIRQSTNsGAKYEGTWNNGLQDGYGTETYADGGTYQGQFTNGMRHGYGV 143
Cdd:COG4642 194 DVYEGEFKNGQRHGQGTYTYAD-GDRYEGEFKNGKRHGQGTLTYADGDRYEGEFKNGKRHGQGT 256
COG4642 COG4642
Uncharacterized conserved protein [Function unknown];
2-135 5.93e-23

Uncharacterized conserved protein [Function unknown];


Pssm-ID: 443680 [Multi-domain]  Cd Length: 271  Bit Score: 99.26  E-value: 5.93e-23
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 83816931   2 SGGRFDFDDGGAYCGGWEGGKAHGHGLCTGPKGqGEYSGSWNFG-FEVAGVYTWPSGNTFEGYWSQGKRHGLGIET-KGR 79
Cdd:COG4642 138 GGGIYTFPNGDVYEGEFKNGKPHGQGTLTYADG-DRYEGEFKNGkRHGQGTLTYANGDVYEGEFKNGQRHGQGTYTyADG 216

                        90       100       110       120       130
                ....*....|....*....|....*....|....*....|....*....|....*....
gi 83816931  80 WLYKGEWTHGF---KGRYgirqSTNSGAKYEGTWNNGLQDGYGTETYADGGTYQGQFTN 135
Cdd:COG4642 217 DRYEGEFKNGKrhgQGTL----TYADGDRYEGEFKNGKRHGQGTMTYADGSVYEGEWKN 271
COG4642 COG4642
Uncharacterized conserved protein [Function unknown];
3-143 6.65e-23

Uncharacterized conserved protein [Function unknown];


Pssm-ID: 443680 [Multi-domain]  Cd Length: 271  Bit Score: 98.88  E-value: 6.65e-23
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 83816931   3 GGRFDFDDGGAYCGGWEGGKAHGHGLCTGPKGQGEYSGSWNFGFEVAGVYTWPSGNTFEGYWSQGKRHGlgietKGRWLY 82
Cdd:COG4642  93 GGEGGFGGGGGGGGGKKGGGGGGGGVLEGDDGGGYGGGTADGGRGGGGIYTFPNGDVYEGEFKNGKPHG-----QGTLTY 167

                        90       100       110       120       130       140
                ....*....|....*....|....*....|....*....|....*....|....*....|.
gi 83816931  83 KgewthgfkgrygirqstnSGAKYEGTWNNGLQDGYGTETYADGGTYQGQFTNGMRHGYGV 143
Cdd:COG4642 168 A------------------DGDRYEGEFKNGKRHGQGTLTYANGDVYEGEFKNGQRHGQGT 210
COG4642 COG4642
Uncharacterized conserved protein [Function unknown];
9-346 2.49e-20

Uncharacterized conserved protein [Function unknown];


Pssm-ID: 443680 [Multi-domain]  Cd Length: 271  Bit Score: 91.56  E-value: 2.49e-20
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 83816931   9 DDGGAYCGGWEGGKAHGHGLCTGPKGQGEYSGSWNFGFEVAGVYTWPSGNTFEGYWSQGKRHGLGIETKGRWL-YKGEWT 87
Cdd:COG4642  41 PGGGGYGGGADGGGGGGGGTGVAGGGGGEGGVTAAGGGGGGGGGKGDGGDGGGGEGGFGGGGGGGGGKKGGGGgGGGVLE 120

                        90       100       110       120       130       140       150       160
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 83816931  88 HGFKGRYGIRQSTNS-----------GAKYEGTWNNGLQDGYGTETYADGGTYQGQFTNGMRHGYGVRQsvpygmavvvr 156
Cdd:COG4642 121 GDDGGGYGGGTADGGrggggiytfpnGDVYEGEFKNGKPHGQGTLTYADGDRYEGEFKNGKRHGQGTLT----------- 189

                       170       180       190       200       210       220       230       240
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 83816931 157 splrtslsslrseHSNGTVapdspaadgptlplppvprggfalsllataeaarppglftrgallgrlrrsesrtslgsqr 236
Cdd:COG4642 190 -------------YANGDV------------------------------------------------------------- 195

                       250       260       270       280       290       300       310       320
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 83816931 237 srlsflkselssgasdaastgslaegaegpddaaapfdadidatttetYMGEWKNDKRSGFGVSERSSGLRYEGEWLDNL 316
Cdd:COG4642 196 ------------------------------------------------YEGEFKNGQRHGQGTYTYADGDRYEGEFKNGK 227

                       330       340       350
                ....*....|....*....|....*....|.
gi 83816931 317 RHGYGRTTLPDGHREEGKYRHNVLV-KGTKR 346
Cdd:COG4642 228 RHGQGTLTYADGDRYEGEFKNGKRHgQGTMT 258
PLN03185 PLN03185
phosphatidylinositol phosphate kinase; Provisional
 4-143 5.65e-20

phosphatidylinositol phosphate kinase; Provisional


Pssm-ID: 215619 [Multi-domain]  Cd Length: 765  Bit Score: 94.90  E-value: 5.65e-20
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 83816931    4 GRFDFDDGGAYCGGWEGGKAHGHGLCTGPKG---QGEYSGSWNFGFevaGVYTWPSGNTFEGYWSQGKRHGLGIETKGRW 80
Cdd:PLN03185  24 GKYLWSDGCMYEGEWRRGMRHGNGKISWPSGatyEGEFSGGYMHGS---GTYTGTDGTTYKGRWRLNLKHGLGYQRYPNG 100

                         90       100       110       120       130       140
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 83816931   81 -LYKGEWTHGFK---GRYgirqSTNSGAKYEGTWNNGLQDGYGTETYADGGTYQGQFTNGMRHGYGV 143
Cdd:PLN03185 101 dVFEGSWIQGLQegpGKY----TWANGNVYLGDMKGGKMSGKGTLTWVSGDSYEGQWLDGMMHGFGV 163
PLN03185 PLN03185
phosphatidylinositol phosphate kinase; Provisional
 38-328 7.94e-11

phosphatidylinositol phosphate kinase; Provisional


Pssm-ID: 215619 [Multi-domain]  Cd Length: 765  Bit Score: 65.24  E-value: 7.94e-11
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 83816931   38 YSGSWNFGF-EVAGVYTWPSGNTFEGYWSQGKRHGLGietKGRWlykgewthgfkgrygirqstNSGAKYEGTWNNGLQD 116
Cdd:PLN03185  11 YSGSLLGNVpEGPGKYLWSDGCMYEGEWRRGMRHGNG---KISW--------------------PSGATYEGEFSGGYMH 67

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 83816931  117 GYGTETYADGGTYQGQFTNGMRHGYGvrqsvpygmavvvrsplrtslsslRSEHSNGTVAPDSpAADGptlplppVPRGg 196
Cdd:PLN03185  68 GSGTYTGTDGTTYKGRWRLNLKHGLG------------------------YQRYPNGDVFEGS-WIQG-------LQEG- 114

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 83816931  197 falsllataeaarpPGLFTrgallgrlrrsesrtslgsqrsrlsflkselssgasdaastgsLAEGAEgpddaaapfdad 276
Cdd:PLN03185 115 --------------PGKYT-------------------------------------------WANGNV------------ 125

                        250       260       270       280       290
                 ....*....|....*....|....*....|....*....|....*....|..
gi 83816931  277 idatttetYMGEWKNDKRSGFGVSERSSGLRYEGEWLDNLRHGYGRTTLPDG 328
Cdd:PLN03185 126 --------YLGDMKGGKMSGKGTLTWVSGDSYEGQWLDGMMHGFGVYTWSDG 169
PLN03185 PLN03185
phosphatidylinositol phosphate kinase; Provisional
 4-120 3.66e-07

phosphatidylinositol phosphate kinase; Provisional


Pssm-ID: 215619 [Multi-domain]  Cd Length: 765  Bit Score: 53.68  E-value: 3.66e-07
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 83816931    4 GRFDFDDGGAYCGGWEGGKAHGHglctgpkgqgeysgswnfgfevaGVYTWPSGNTFEGYWSQGKRHGLGIETkgrWlyk 83
Cdd:PLN03185 116 GKYTWANGNVYLGDMKGGKMSGK-----------------------GTLTWVSGDSYEGQWLDGMMHGFGVYT---W--- 166

                         90       100       110
                 ....*....|....*....|....*....|....*..
gi 83816931   84 gewthgfkgrygirqstNSGAKYEGTWNNGLQDGYGT 120
Cdd:PLN03185 167 -----------------SDGGCYVGTWTRGLKDGKGV 186
PHA03247 PHA03247
large tegument protein UL36; Provisional
 446-633 5.77e-07

large tegument protein UL36; Provisional


Pssm-ID: 223021 [Multi-domain]  Cd Length: 3151  Bit Score: 53.40  E-value: 5.77e-07
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 83816931   446 PRERGPGTGLPERPRESPQLHERETPQPEGGPPSPAGTPPQPKR---PRPGSSKDGLLSPgawNGEPGGEGSRPATPSDG 522
Cdd:PHA03247 2663 RPRRARRLGRAAQASSPPQRPRRRAARPTVGSLTSLADPPPPPPtpePAPHALVSATPLP---PGPAAARQASPALPAAP 2739

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 83816931   523 AGRRSPARPASEhMAIEALQPPPAPSREPEVALYRGYHSYAVRTGPPEPPPLEDEPEPEPEVPRSDSEPPSPVSAtvqee 602
Cdd:PHA03247 2740 APPAVPAGPATP-GGPARPARPPTTAGPPAPAPPAAPAAGPPRRLTRPAVASLSESRESLPSPWDPADPPAAVLA----- 2813

                         170       180       190
                  ....*....|....*....|....*....|...
gi 83816931   603 esPAPRSRVPAKPATLEPKP--IVPKAEPKAKA 633
Cdd:PHA03247 2814 --PAAALPPAASPAGPLPPPtsAQPTAPPPPPG 2844
PHA03307 PHA03307
transcriptional regulator ICP4; Provisional
 442-639 1.34e-06

transcriptional regulator ICP4; Provisional


Pssm-ID: 223039 [Multi-domain]  Cd Length: 1352  Bit Score: 52.10  E-value: 1.34e-06
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 83816931   442 SLLEPRERGPGTGLPERPRESPQLHERETPQPEGGPPSPAGTPPQPKRPR-----PGSSKDGLLSPGAWNGEPGGEG--- 513
Cdd:PHA03307  177 SSPEETARAPSSPPAEPPPSTPPAAASPRPPRRSSPISASASSPAPAPGRsaaddAGASSSDSSSSESSGCGWGPENecp 256

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 83816931   514 ----------SRPATPSDGAGRRSPARPASEHMAIEALQPPPAPSREpevalyrgyHSYAVRTGPPEPPPLEDEPEPEPE 583
Cdd:PHA03307  257 lprpapitlpTRIWEASGWNGPSSRPGPASSSSSPRERSPSPSPSSP---------GSGPAPSSPRASSSSSSSRESSSS 327

                         170       180       190       200       210
                  ....*....|....*....|....*....|....*....|....*....|....*.
gi 83816931   584 VPRSDSEPPSPVSATVQEEESPAPRSRVPAKPATLEPKPIVPKAEPKAKARKTEAR 639
Cdd:PHA03307  328 STSSSSESSRGAAVSPGPSPSRSPSPSRPPPPADPSSPRKRPRPSRAPSSPAASAG 383
PHA03307 PHA03307
transcriptional regulator ICP4; Provisional
 435-638 1.55e-06

transcriptional regulator ICP4; Provisional


Pssm-ID: 223039 [Multi-domain]  Cd Length: 1352  Bit Score: 51.71  E-value: 1.55e-06
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 83816931   435 EILENSESLLEPRERGPGTGLPERPRESPQLHERETPQPEGGPPSPAGTPPQPKRPRPGSSKDGLLSPGAWNGE-PGGEG 513
Cdd:PHA03307   78 EAPANESRSTPTWSLSTLAPASPAREGSPTPPGPSSPDPPPPTPPPASPPPSPAPDLSEMLRPVGSPGPPPAASpPAAGA 157

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 83816931   514 SRPATPSDGAGRRSPARPASEHMAIEALQPPPAPSREPEVALYRGYHSYAVRTGPPEPPPLEDEPEPEPEVPRSDSEPPS 593
Cdd:PHA03307  158 SPAAVASDAASSRQAALPLSSPEETARAPSSPPAEPPPSTPPAAASPRPPRRSSPISASASSPAPAPGRSAADDAGASSS 237

                         170       180       190       200
                  ....*....|....*....|....*....|....*....|....*
gi 83816931   594 PVSATVQEEESPAPRSRVPAKPATLEPKPIVPKAEPKAKARKTEA 638
Cdd:PHA03307  238 DSSSSESSGCGWGPENECPLPRPAPITLPTRIWEASGWNGPSSRP 282
PHA03247 PHA03247
large tegument protein UL36; Provisional
 445-634 4.15e-05

large tegument protein UL36; Provisional


Pssm-ID: 223021 [Multi-domain]  Cd Length: 3151  Bit Score: 47.24  E-value: 4.15e-05
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 83816931   445 EPRERGPGTGLPERPRESPQLHERETPQPeggPPSPAGTPPQPKRPRPGSSKDGLLSPGAWNGEPGG-EGSRPATPSDGA 523
Cdd:PHA03247 2903 DQPERPPQPQAPPPPQPQPQPPPPPQPQP---PPPPPPRPQPPLAPTTDPAGAGEPSGAVPQPWLGAlVPGRVAVPRFRV 2979

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 83816931   524 GRRSPARPASEhmaiealQPPPAPSREPEVALYRGYHSYAVRTGPPEPPPL-EDEPEPEPEVPRSDSEPPSPVSATVQEE 602
Cdd:PHA03247 2980 PQPAPSREAPA-------SSTPPLTGHSLSRVSSWASSLALHEETDPPPVSlKQTLWPPDDTEDSDADSLFDSDSERSDL 3052

                         170       180       190
                  ....*....|....*....|....*....|..
gi 83816931   603 ESPAPRSRVPAKPATLEPKPIVPKAEPKAKAR 634
Cdd:PHA03247 3053 EALDPLPPEPHDPFAHEPDPATPEAGARESPS 3084
PHA03247 PHA03247
large tegument protein UL36; Provisional
 450-638 8.11e-05

large tegument protein UL36; Provisional


Pssm-ID: 223021 [Multi-domain]  Cd Length: 3151  Bit Score: 46.08  E-value: 8.11e-05
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 83816931   450 GPGTGLPERPRESPQLHERETPQPegGPPSPAGTPPQPKRPRPGSSKDGllSPGAWNGEPGGEGSRPATPSDGAGRRSPa 529
Cdd:PHA03247 2813 APAAALPPAASPAGPLPPPTSAQP--TAPPPPPGPPPPSLPLGGSVAPG--GDVRRRPPSRSPAAKPAAPARPPVRRLA- 2887

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 83816931   530 RPASEHMAIEALQPPPAPSREPEvalyrgyhsyavrtgppepppledepepepevprsdsePPSPVSATVQEEESPAPRS 609
Cdd:PHA03247 2888 RPAVSRSTESFALPPDQPERPPQ--------------------------------------PQAPPPPQPQPQPPPPPQP 2929

                         170       180
                  ....*....|....*....|....*....
gi 83816931   610 RVPAKPATLEPKPIVPKAEPKAKARKTEA 638
Cdd:PHA03247 2930 QPPPPPPPRPQPPLAPTTDPAGAGEPSGA 2958
YwqK COG2849
Antitoxin component YwqK of the YwqJK toxin-antitoxin module [Defense mechanisms];
36-139 8.76e-05

Antitoxin component YwqK of the YwqJK toxin-antitoxin module [Defense mechanisms];


Pssm-ID: 442097 [Multi-domain]  Cd Length: 163  Bit Score: 43.52  E-value: 8.76e-05
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 83816931  36 GEYSGSWNFGFEVAGVYTW--PSGN-TFEGYWSQGKRHGLGIE--TKGRWLYKGEWTHGFK-GRYgiRQSTNSGA-KYEG 108
Cdd:COG2849  54 KLGKGLGKYKKGKLGEWKTyyPNGQlKSEGTYKNGKLEGEWKEyyENGKLKSEGNYKNGKLhGEW--KEYYENGKlKEEG 131

                        90       100       110
                ....*....|....*....|....*....|..
gi 83816931 109 TWNNGLQDGYGTETYADGG-TYQGQFTNGMRH 139
Cdd:COG2849 132 NYKNGKKDGVWKYYDENGKlVKEEEYKNGKKV 163
MORN pfam02493
MORN repeat; The MORN (Membrane Occupation and Recognition Nexus) repeat is found in multiple ...
 106-128 1.44e-04

MORN repeat; The MORN (Membrane Occupation and Recognition Nexus) repeat is found in multiple copies in several proteins including junctophilins (See Takeshima et al. Mol. Cell 2000;6:11-22). A MORN-repeat protein has been identified in the parasite Toxoplasma gondiis a dynamic component of cell division apparatus in Toxoplasma gondii. It has been hypothesized to functions as a linker protein between certain membrane regions and the parasite's cytoskeleton.


Pssm-ID: 308220 [Multi-domain]  Cd Length: 23  Bit Score: 39.31  E-value: 1.44e-04
                          10        20
                  ....*....|....*....|...
gi 83816931   106 YEGTWNNGLQDGYGTETYADGGT 128
Cdd:pfam02493   1 YEGEWKNGKRHGKGVYTWPDGDR 23
PRK07764 PRK07764
DNA polymerase III subunits gamma and tau; Validated
 449-552 2.01e-04

DNA polymerase III subunits gamma and tau; Validated


Pssm-ID: 236090 [Multi-domain]  Cd Length: 824  Bit Score: 44.59  E-value: 2.01e-04
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 83816931  449 RGPGTGLPERPRESPQLHERETPQPEGGPPSPAGTPPQPKRPRPGSSKDGLLSPGAWNGEPGGEGSRPATPSDGAGRRSP 528
Cdd:PRK07764 398 APSAAAAAPAAAPAPAAAAPAAAAAPAPAAAPQPAPAPAPAPAPPSPAGNAPAGGAPSPPPAAAPSAQPAPAPAAAPEPT 477

                         90       100
                 ....*....|....*....|....
gi 83816931  529 ARPASEHMAIEALQPPPAPSREPE 552
Cdd:PRK07764 478 AAPAPAPPAAPAPAAAPAAPAAPA 501
PHA03247 PHA03247
large tegument protein UL36; Provisional
 450-633 2.22e-04

large tegument protein UL36; Provisional


Pssm-ID: 223021 [Multi-domain]  Cd Length: 3151  Bit Score: 44.93  E-value: 2.22e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 83816931   450 GPGTGLPERPRESPQLHERETPQPEGGPPSPA--------GTPPQPKRPRpgsskdgllSPGAWNGEPggegsrpatpsd 521
Cdd:PHA03247 2550 DPPPPLPPAAPPAAPDRSVPPPRPAPRPSEPAvtsrarrpDAPPQSARPR---------APVDDRGDP------------ 2608

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 83816931   522 gagrRSPARPASEHMAIEALQPPPaPSREPEVALYRGYHSYAVRTGPPEPPPLEDEPEPEPEVPRSDSEPPSPvSATVQE 601
Cdd:PHA03247 2609 ----RGPAPPSPLPPDTHAPDPPP-PSPSPAANEPDPHPPPTVPPPERPRDDPAPGRVSRPRRARRLGRAAQA-SSPPQR 2682

                         170       180       190
                  ....*....|....*....|....*....|..
gi 83816931   602 EESPAPRSRVPAKPATLEPKPIVPKAEPKAKA 633
Cdd:PHA03247 2683 PRRRAARPTVGSLTSLADPPPPPPTPEPAPHA 2714
PLN03185 PLN03185
phosphatidylinositol phosphate kinase; Provisional
 284-339 3.44e-04

phosphatidylinositol phosphate kinase; Provisional


Pssm-ID: 215619 [Multi-domain]  Cd Length: 765  Bit Score: 44.05  E-value: 3.44e-04
                         10        20        30        40        50
                 ....*....|....*....|....*....|....*....|....*....|....*.
gi 83816931  284 TYMGEWKNDKRSGFGVSERSSGLRYEGEWLDNLRHGYGRTTLPDGHREEGKYRHNV 339
Cdd:PLN03185  33 MYEGEWRRGMRHGNGKISWPSGATYEGEFSGGYMHGSGTYTGTDGTTYKGRWRLNL 88
PHA03264 PHA03264
envelope glycoprotein D; Provisional
 471-551 3.67e-04

envelope glycoprotein D; Provisional


Pssm-ID: 223029 [Multi-domain]  Cd Length: 416  Bit Score: 43.46  E-value: 3.67e-04
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 83816931  471 PQPEGGPPSPAGTPPQPKRPRPGSSKDGllsPGAWNGEPGGEGSRPATPSDGAG---RRSPARPASEHMAIEALQPPPAP 547
Cdd:PHA03264 268 PAPSGGSPAPPGDDRPEAKPEPGPVEDG---APGRETGGEGEGPEPAGRDGAAGgepKPGPPRPAPDADRPEGWPSLEAI 344


                 ....
gi 83816931  548 SREP 551
Cdd:PHA03264 345 TFPP 348
MORN smart00698
Possible plasma membrane-binding motif in junctophilins, PIP-5-kinases and protein kinases;
307-327 3.88e-04

Possible plasma membrane-binding motif in junctophilins, PIP-5-kinases and protein kinases;


Pssm-ID: 197832 [Multi-domain]  Cd Length: 22  Bit Score: 38.09  E-value: 3.88e-04
                           10        20
                   ....*....|....*....|.
gi 83816931    307 RYEGEWLDNLRHGYGRTTLPD 327
Cdd:smart00698   2 RYEGEWRNGKRHGRGVYTYAN 22
MORN pfam02493
MORN repeat; The MORN (Membrane Occupation and Recognition Nexus) repeat is found in multiple ...
 308-330 5.05e-04

MORN repeat; The MORN (Membrane Occupation and Recognition Nexus) repeat is found in multiple copies in several proteins including junctophilins (See Takeshima et al. Mol. Cell 2000;6:11-22). A MORN-repeat protein has been identified in the parasite Toxoplasma gondiis a dynamic component of cell division apparatus in Toxoplasma gondii. It has been hypothesized to functions as a linker protein between certain membrane regions and the parasite's cytoskeleton.


Pssm-ID: 308220 [Multi-domain]  Cd Length: 23  Bit Score: 37.77  E-value: 5.05e-04
                          10        20
                  ....*....|....*....|...
gi 83816931   308 YEGEWLDNLRHGYGRTTLPDGHR 330
Cdd:pfam02493   1 YEGEWKNGKRHGKGVYTWPDGDR 23
PHA03247 PHA03247
large tegument protein UL36; Provisional
 410-642 1.11e-03

large tegument protein UL36; Provisional


Pssm-ID: 223021 [Multi-domain]  Cd Length: 3151  Bit Score: 42.62  E-value: 1.11e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 83816931   410 RTLAKELAPDFYQPgPEYQKRRLLQEILENSESLLEPRERGPgtglpeRPRESPQLHERETPQPEGGPPSPAGTPPQPKR 489
Cdd:PHA03247 2666 RARRLGRAAQASSP-PQRPRRRAARPTVGSLTSLADPPPPPP------TPEPAPHALVSATPLPPGPAAARQASPALPAA 2738

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 83816931   490 PRPGSSKDGLLSPGAWNGEPG-------GEGSRPATPSDGAGRRSPARP-ASEHMAIEALQPPPAPSREPEVALYRgyhS 561
Cdd:PHA03247 2739 PAPPAVPAGPATPGGPARPARppttagpPAPAPPAAPAAGPPRRLTRPAvASLSESRESLPSPWDPADPPAAVLAP---A 2815

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 83816931   562 YAVRTGPPEPPPLEDEPEPEPEVPRSDSEPPSPVSATvqeEESPAPRSRVPAKPATLEPkPIVPKAEPKAKARKTEARGL 641
Cdd:PHA03247 2816 AALPPAASPAGPLPPPTSAQPTAPPPPPGPPPPSLPL---GGSVAPGGDVRRRPPSRSP-AAKPAAPARPPVRRLARPAV 2891


                  .
gi 83816931   642 S 642
Cdd:PHA03247 2892 S 2892
DUF3827 pfam12877
Domain of unknown function (DUF3827); This family contains the Swiss:Q9HCM3 protein which has ...
 424-531 1.73e-03

Domain of unknown function (DUF3827); This family contains the Swiss:Q9HCM3 protein which has been found to be fused fused to BRAF gene in many cases of pilocytic astrocytomas. The fusion is due mainly to a tandem duplication of 2 Mb at 7q34. Although nothing is known about the function of Swiss:Q9HCM3 protein, the BRAF protein is a well characterized oncoprotein. It is a serine/threonine protein kinase which is implicated in MAP/ERK signalling, a critical pathway for the regulation of cell division, differentiation and secretion.


Pssm-ID: 463737  Cd Length: 677  Bit Score: 41.70  E-value: 1.73e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 83816931   424 GPEYQKRRLLQEileNSESLLEPRERGPgtgLPERPRESPQLHERETPQPEGGPPSPAGTPPQPKRPRPGSSKDGLLSPG 503
Cdd:pfam12877 316 GFDFAKQHLGQH---SKDDVPVIQEPAP---LPLPVKDATPSENGEVPTPKSKTSSKTSRGERRRGRISPSDGDSVGSDE 389

                          90       100
                  ....*....|....*....|....*....
gi 83816931   504 AWNGEPGGEGSRP-ATPSDGAGRRSPARP 531
Cdd:pfam12877 390 SSKRESGEESPRPaATPSDGKQHRKTNRP 418
PRK07764 PRK07764
DNA polymerase III subunits gamma and tau; Validated
 445-621 1.89e-03

DNA polymerase III subunits gamma and tau; Validated


Pssm-ID: 236090 [Multi-domain]  Cd Length: 824  Bit Score: 41.51  E-value: 1.89e-03
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 83816931  445 EPRERGPGTGLPERPRESPQLHERETPQPEGGPPSPAGTPPQPKRPRPGSSkdglLSPGAWNGEPGGEGSRPATPSDGAG 524
Cdd:PRK07764 650 PEHHPKHVAVPDASDGGDGWPAKAGGAAPAAPPPAPAPAAPAAPAGAAPAQ----PAPAPAATPPAGQADDPAAQPPQAA 725

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 83816931  525 RRSPARPASEHMAIEalqPPPAPSREPEVALYrGYHSYAVRTGPpepppledepepepevPRSDSEPPSPVSATVQEEES 604
Cdd:PRK07764 726 QGASAPSPAADDPVP---LPPEPDDPPDPAGA-PAQPPPPPAPA----------------PAAAPAAAPPPSPPSEEEEM 785

                        170
                 ....*....|....*..
gi 83816931  605 PAPRSRVPAKPATLEPK 621
Cdd:PRK07764 786 AEDDAPSMDDEDRRDAE 802
PHA03247 PHA03247
large tegument protein UL36; Provisional
 456-631 2.01e-03

large tegument protein UL36; Provisional


Pssm-ID: 223021 [Multi-domain]  Cd Length: 3151  Bit Score: 41.85  E-value: 2.01e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 83816931   456 PERPRESPQLHERETPQPEGGPPSPAGTPPQPKRPRPGSSKDGLLSPGAWNGEPGGEGS-RPATPSDGAGRRSPARPASE 534
Cdd:PHA03247 2649 PERPRDDPAPGRVSRPRRARRLGRAAQASSPPQRPRRRAARPTVGSLTSLADPPPPPPTpEPAPHALVSATPLPPGPAAA 2728

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 83816931   535 HMAIEALQPPPAPSREPEVALYRGYHSYAVRTGPPEPPPLEDEPEPEPEVPRSDSEPPSPVSATVQEEESPAPRSRVPAK 614
Cdd:PHA03247 2729 RQASPALPAAPAPPAVPAGPATPGGPARPARPPTTAGPPAPAPPAAPAAGPPRRLTRPAVASLSESRESLPSPWDPADPP 2808

                         170
                  ....*....|....*..
gi 83816931   615 PATLEPKPIVPKAEPKA 631
Cdd:PHA03247 2809 AAVLAPAAALPPAASPA 2825
PLN03209 PLN03209
translocon at the inner envelope of chloroplast subunit 62; Provisional
 440-635 2.21e-03

translocon at the inner envelope of chloroplast subunit 62; Provisional


Pssm-ID: 178748 [Multi-domain]  Cd Length: 576  Bit Score: 41.07  E-value: 2.21e-03
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 83816931  440 SESLLEPRERGPGTGLPERPreSPQLhERETPQPEG----------------GPPSPAGTPPQPKRPRPGSSkDGLLSPG 503
Cdd:PLN03209 333 SDAADGPKPVPTKPVTPEAP--SPPI-EEEPPQPKAvvprplspytayedlkPPTSPIPTPPSSSPASSKSV-DAVAKPA 408

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 83816931  504 AWNGEPGgEGSRPATPSDGAGR--RSPARPASEHMAIEALQPPPAPSREPEVALYRGYHSYAVRTGPPEPPPLEDEPEPE 581
Cdd:PLN03209 409 EPDVVPS-PGSASNVPEVEPAQveAKKTRPLSPYARYEDLKPPTSPSPTAPTGVSPSVSSTSSVPAVPDTAPATAATDAA 487

                        170       180       190       200       210
                 ....*....|....*....|....*....|....*....|....*....|....*..
gi 83816931  582 PEVPRSDSE-PPSPVSATVQEEESPAPRSRVP--AKPATLEPKPIVPKAEPKAKARK 635
Cdd:PLN03209 488 APPPANMRPlSPYAVYDDLKPPTSPSPAAPVGkvAPSSTNEVVKVGNSAPPTALADE 544
Vinculin pfam01044
Vinculin family;
413-497 2.55e-03

Vinculin family;


Pssm-ID: 460040  Cd Length: 852  Bit Score: 41.25  E-value: 2.55e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 83816931   413 AKELAPDFYQPGPEYQKRRLLQEILENS----ESLLEPRERGPGTGLPERPRESPQLHERETPQPEGGPPSPAGTPPQPK 488
Cdd:pfam01044 571 AKEVAVNALDPGAAKSWEENNYEFLDAVrlvyDAVRPIRQAVLMNRSPPELPTDSEFELREDEPAPPRPPPPVETEPPPR 650


                  ....*....
gi 83816931   489 RPRPGSSKD 497
Cdd:pfam01044 651 PPPPPETDR 659
MORN smart00698
Possible plasma membrane-binding motif in junctophilins, PIP-5-kinases and protein kinases;
104-125 4.32e-03

Possible plasma membrane-binding motif in junctophilins, PIP-5-kinases and protein kinases;


Pssm-ID: 197832 [Multi-domain]  Cd Length: 22  Bit Score: 35.01  E-value: 4.32e-03
                           10        20
                   ....*....|....*....|..
gi 83816931    104 AKYEGTWNNGLQDGYGTETYAD 125
Cdd:smart00698   1 DRYEGEWRNGKRHGRGVYTYAN 22
PHA03247 PHA03247
large tegument protein UL36; Provisional
 446-638 5.43e-03

large tegument protein UL36; Provisional


Pssm-ID: 223021 [Multi-domain]  Cd Length: 3151  Bit Score: 40.31  E-value: 5.43e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 83816931   446 PRERGPGTGLPERPRESPQLHERETPQ-PEGGPPSPAGTPPQPKRPRPGSSkdglLSPGAWNGEPGGEGSRPATPSDGAG 524
Cdd:PHA03247 2799 PSPWDPADPPAAVLAPAAALPPAASPAgPLPPPTSAQPTAPPPPPGPPPPS----LPLGGSVAPGGDVRRRPPSRSPAAK 2874

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 83816931   525 RRSPARPASEHMAIEALQPPPAPSREPEVALYRGYHSYAVRTGPPEPPPLEDEPEPEPEVPRSDSEPPSPVSATVQEEES 604
Cdd:PHA03247 2875 PAAPARPPVRRLARPAVSRSTESFALPPDQPERPPQPQAPPPPQPQPQPPPPPQPQPPPPPPPRPQPPLAPTTDPAGAGE 2954

                         170       180       190
                  ....*....|....*....|....*....|....*.
gi 83816931   605 PAPRSRVPAKPATLEPKPIVPK--AEPKAKARKTEA 638
Cdd:PHA03247 2955 PSGAVPQPWLGALVPGRVAVPRfrVPQPAPSREAPA 2990
PRK12323 PRK12323
DNA polymerase III subunit gamma/tau;
510-631 5.78e-03

DNA polymerase III subunit gamma/tau;


Pssm-ID: 237057 [Multi-domain]  Cd Length: 700  Bit Score: 39.86  E-value: 5.78e-03
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 83816931  510 GGEGSRPATPSDG-AGRRSPARPASEHMAIEALQPPPAPSREPEVALYRGYHSYAVRTGPPEPPPLEDEPEPEPEVPRSD 588
Cdd:PRK12323 368 SGGGAGPATAAAApVAQPAPAAAAPAAAAPAPAAPPAAPAAAPAAAAAARAVAAAPARRSPAPEALAAARQASARGPGGA 447

                         90       100       110       120
                 ....*....|....*....|....*....|....*....|....
gi 83816931  589 SEP-PSPVSATVQEEESPAPRSRVPAKPATLEPKPIVPKAEPKA 631
Cdd:PRK12323 448 PAPaPAPAAAPAAAARPAAAGPRPVAAAAAAAPARAAPAAAPAP 491
PHA03378 PHA03378
EBNA-3B; Provisional
 444-554 8.06e-03

EBNA-3B; Provisional


Pssm-ID: 223065 [Multi-domain]  Cd Length: 991  Bit Score: 39.67  E-value: 8.06e-03
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 83816931  444 LEPRERGPGtglPERPRESPQLHERETPQPEGGPPSPAGTPPQPKRPR--PGSSKDGLLSPGAWNgEPGGEGSRPATPSD 521
Cdd:PHA03378 694 MQPPPRAPT---PMRPPAAPPGRAQRPAAATGRARPPAAAPGRARPPAaaPGRARPPAAAPGRAR-PPAAAPGRARPPAA 769

                         90       100       110
                 ....*....|....*....|....*....|...
gi 83816931  522 GAGRRSPARPAsehmaiealQPPPAPSREPEVA 554
Cdd:PHA03378 770 APGAPTPQPPP---------QAPPAPQQRPRGA 793
PRK12323 PRK12323
DNA polymerase III subunit gamma/tau;
470-636 9.33e-03

DNA polymerase III subunit gamma/tau;


Pssm-ID: 237057 [Multi-domain]  Cd Length: 700  Bit Score: 39.09  E-value: 9.33e-03
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 83816931  470 TPQPEGGPPSPAGTPPQPKRPRPGSSKDGLLSPG------AWNGEPGGEGSRPATPSDGAGRRSPARPAsehmAIEALQP 543
Cdd:PRK12323 396 APAPAAPPAAPAAAPAAAAAARAVAAAPARRSPApealaaARQASARGPGGAPAPAPAPAAAPAAAARP----AAAGPRP 471

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 83816931  544 PPAPSREPEVALYRGYHSYAVRT---------GPPEPPPLEDEPEPEPEVPRSDSEPPSPVSATVQEEESPAPRSRVPAK 614
Cdd:PRK12323 472 VAAAAAAAPARAAPAAAPAPADDdpppweelpPEFASPAPAQPDAAPAGWVAESIPDPATADPDDAFETLAPAPAAAPAP 551

                        170       180
                 ....*....|....*....|..
gi 83816931  615 PATLEPKPIVPKAEPKAKARKT 636
Cdd:PRK12323 552 RAAAATEPVVAPRPPRASASGL 573
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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