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Conserved domains on  [gi|89001111|ref|NP_001034740|]
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suppressor APC domain-containing protein 1 [Homo sapiens]

Protein Classification

Suppressor_APC domain-containing protein( domain architecture ID 10568565)

Suppressor_APC domain-containing protein

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
Suppressor_APC pfam11414
Adenomatous polyposis coli tumour suppressor protein; The tumour suppressor protein, APC, has ...
 35-114 2.74e-23

Adenomatous polyposis coli tumour suppressor protein; The tumour suppressor protein, APC, has a nuclear export activity as well as many different intracellular functions. The structure consists of three alpha-helices forming two separate antiparallel coiled coils.


:

Pssm-ID: 463275  Cd Length: 82  Bit Score: 87.70  E-value: 2.74e-23
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 89001111    35 FFLWLRRMQALEREQDALWQGLELLQHGQAWFEDHLREAQRQQLHLGALGENF--LTDLHSEPGRPPLAQIQKVNICLQN 112
Cdd:pfam11414   1 DYNMLKRMKQLEQEKDVLLQGLEMVERARDWYQQQLQEVQERQKYLGANGTYFdyGSDAQQERLEFLLARIQEVNRCLGG 80


                  ..
gi 89001111   113 LI 114
Cdd:pfam11414  81 LI 82
 
Name Accession Description Interval E-value
Suppressor_APC pfam11414
Adenomatous polyposis coli tumour suppressor protein; The tumour suppressor protein, APC, has ...
 35-114 2.74e-23

Adenomatous polyposis coli tumour suppressor protein; The tumour suppressor protein, APC, has a nuclear export activity as well as many different intracellular functions. The structure consists of three alpha-helices forming two separate antiparallel coiled coils.


Pssm-ID: 463275  Cd Length: 82  Bit Score: 87.70  E-value: 2.74e-23
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 89001111    35 FFLWLRRMQALEREQDALWQGLELLQHGQAWFEDHLREAQRQQLHLGALGENF--LTDLHSEPGRPPLAQIQKVNICLQN 112
Cdd:pfam11414   1 DYNMLKRMKQLEQEKDVLLQGLEMVERARDWYQQQLQEVQERQKYLGANGTYFdyGSDAQQERLEFLLARIQEVNRCLGG 80


                  ..
gi 89001111   113 LI 114
Cdd:pfam11414  81 LI 82
 
Name Accession Description Interval E-value
Suppressor_APC pfam11414
Adenomatous polyposis coli tumour suppressor protein; The tumour suppressor protein, APC, has ...
 35-114 2.74e-23

Adenomatous polyposis coli tumour suppressor protein; The tumour suppressor protein, APC, has a nuclear export activity as well as many different intracellular functions. The structure consists of three alpha-helices forming two separate antiparallel coiled coils.


Pssm-ID: 463275  Cd Length: 82  Bit Score: 87.70  E-value: 2.74e-23
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 89001111    35 FFLWLRRMQALEREQDALWQGLELLQHGQAWFEDHLREAQRQQLHLGALGENF--LTDLHSEPGRPPLAQIQKVNICLQN 112
Cdd:pfam11414   1 DYNMLKRMKQLEQEKDVLLQGLEMVERARDWYQQQLQEVQERQKYLGANGTYFdyGSDAQQERLEFLLARIQEVNRCLGG 80


                  ..
gi 89001111   113 LI 114
Cdd:pfam11414  81 LI 82
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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