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Conserved domains on  [gi|223468630|ref|NP_001138551|]
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conserved oligomeric Golgi complex subunit 6 isoform 2 [Homo sapiens]

Protein Classification

conserved oligomeric Golgi complex subunit 6( domain architecture ID 10534004)

conserved oligomeric Golgi complex subunit 6 is a component of the peripheral membrane COG complex that is involved in intra-Golgi protein trafficking

Graphical summary

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List of domain hits

Name Accession Description Interval E-value
COG6 pfam06419
Conserved oligomeric complex COG6; COG6 is a component of the conserved oligomeric golgi ...
56-610 0e+00

Conserved oligomeric complex COG6; COG6 is a component of the conserved oligomeric golgi complex, which is composed of eight different subunits and is required for normal golgi morphology and localization.


:

Pssm-ID: 461904  Cd Length: 611  Bit Score: 712.07  E-value: 0e+00
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 223468630   56 ALKALSTFFVENSLRTRRNLRGDIERKSLAINEEFVSIFKEVKEELESISEDVQAMSNCCQDMTSRLQAAKEQTQDLIVK 135
Cdd:pfam06419   1 ALGSLSEFYTENTAETRRNLRSDIEKELLKINGEFLKEFGPVVEQLKRIETDVEKLNNSCDEMRKRLSAAKEDTAPLLEE 80
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 223468630  136 TTKLQSESQKLEIRAQVADAFLSKFQLTSDEMSLLRGTREgPITEDFFKALGRVKQIHNDVKVLLRTNQQTAGLEIMEQM 215
Cdd:pfam06419  81 ASSLQEQKKKIELKQKLLDAFLDKFTLSEEEEAALTSGEE-PVNDEFFKALAKVKKIHEDCKILLGTENQRAGLEIMEQM 159
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 223468630  216 ALLQETAYERLYRWAQSECRTLTQESCDVSPVLTQAMEALQDRPVLYKYTLDEFGTARRSTVVRGFIDALTRGGPGGTPR 295
Cdd:pfam06419 160 NKYLEAAFEKLYRWTQREFKNLYLENPEISSLLRKALRVLSERPVLFKYCLDEFAEARSKILSDEFISALTRGGPGGSPR 239
                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 223468630  296 PIEMHSHDPLRYVGDMLAWLHQATASEKEHLEALLKHVT--------TQGVEEN----IQEVVGHITEGVCRPLKVRIEQ 363
Cdd:pfam06419 240 PIELSAHDPLRYVGDMLAWVHSAIASEREFLESLFKFCDgdeiakgiQAGNDSElwslIKELLDRILEGVCRPLKQRVEQ 319
                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 223468630  364 VIVAEPGAVLLYKISNLLKFYHHTISGIVGNSAtALLTTIEEMHLLSKKIFFNSLSLHASKLMDKVELPPPDLGPSSALN 443
Cdd:pfam06419 320 VIQSEEDPITLYKIANLLEFYRSMFSKLLGQDS-SLVETLRELEDSAKRKFFSLLRDHLAKLLREPETPPSDLSPPEWLI 398
                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 223468630  444 QTLMLLREVLASHDSSVVP-LDARQADFVQVLSCVLDPLLQMCTVSASNLGTADMATFMVNSLYMMKTTLALFEFTDRRL 522
Cdd:pfam06419 399 DALSLLLELLDTYETSLASeASEREADFKPILSEILDPLLQMCEPSAKKLPKPDMAIFLINCLDLIQSTLSPYSFASDRV 478
                         490       500       510       520       530       540       550       560
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 223468630  523 EMLQFQIEAHLDTLINEQASYVLTRVGLSYIYNTVQQHKPEQG---SLANMPNLDSVTLKAAMVQFDRYLSAPDNLLIPQ 599
Cdd:pfam06419 479 EELQAQIDAHVDTLTEEQASSLLEQSGLSDLYNILNMIFPFYSmyePLSENPGMDPDALRQASQKLDDFLPSALTDAQPN 558
                         570
                  ....*....|.
gi 223468630  600 LNFLLSATVKR 610
Cdd:pfam06419 559 LKKLQSPTLAD 569
 
Name Accession Description Interval E-value
COG6 pfam06419
Conserved oligomeric complex COG6; COG6 is a component of the conserved oligomeric golgi ...
56-610 0e+00

Conserved oligomeric complex COG6; COG6 is a component of the conserved oligomeric golgi complex, which is composed of eight different subunits and is required for normal golgi morphology and localization.


Pssm-ID: 461904  Cd Length: 611  Bit Score: 712.07  E-value: 0e+00
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 223468630   56 ALKALSTFFVENSLRTRRNLRGDIERKSLAINEEFVSIFKEVKEELESISEDVQAMSNCCQDMTSRLQAAKEQTQDLIVK 135
Cdd:pfam06419   1 ALGSLSEFYTENTAETRRNLRSDIEKELLKINGEFLKEFGPVVEQLKRIETDVEKLNNSCDEMRKRLSAAKEDTAPLLEE 80
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 223468630  136 TTKLQSESQKLEIRAQVADAFLSKFQLTSDEMSLLRGTREgPITEDFFKALGRVKQIHNDVKVLLRTNQQTAGLEIMEQM 215
Cdd:pfam06419  81 ASSLQEQKKKIELKQKLLDAFLDKFTLSEEEEAALTSGEE-PVNDEFFKALAKVKKIHEDCKILLGTENQRAGLEIMEQM 159
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 223468630  216 ALLQETAYERLYRWAQSECRTLTQESCDVSPVLTQAMEALQDRPVLYKYTLDEFGTARRSTVVRGFIDALTRGGPGGTPR 295
Cdd:pfam06419 160 NKYLEAAFEKLYRWTQREFKNLYLENPEISSLLRKALRVLSERPVLFKYCLDEFAEARSKILSDEFISALTRGGPGGSPR 239
                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 223468630  296 PIEMHSHDPLRYVGDMLAWLHQATASEKEHLEALLKHVT--------TQGVEEN----IQEVVGHITEGVCRPLKVRIEQ 363
Cdd:pfam06419 240 PIELSAHDPLRYVGDMLAWVHSAIASEREFLESLFKFCDgdeiakgiQAGNDSElwslIKELLDRILEGVCRPLKQRVEQ 319
                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 223468630  364 VIVAEPGAVLLYKISNLLKFYHHTISGIVGNSAtALLTTIEEMHLLSKKIFFNSLSLHASKLMDKVELPPPDLGPSSALN 443
Cdd:pfam06419 320 VIQSEEDPITLYKIANLLEFYRSMFSKLLGQDS-SLVETLRELEDSAKRKFFSLLRDHLAKLLREPETPPSDLSPPEWLI 398
                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 223468630  444 QTLMLLREVLASHDSSVVP-LDARQADFVQVLSCVLDPLLQMCTVSASNLGTADMATFMVNSLYMMKTTLALFEFTDRRL 522
Cdd:pfam06419 399 DALSLLLELLDTYETSLASeASEREADFKPILSEILDPLLQMCEPSAKKLPKPDMAIFLINCLDLIQSTLSPYSFASDRV 478
                         490       500       510       520       530       540       550       560
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 223468630  523 EMLQFQIEAHLDTLINEQASYVLTRVGLSYIYNTVQQHKPEQG---SLANMPNLDSVTLKAAMVQFDRYLSAPDNLLIPQ 599
Cdd:pfam06419 479 EELQAQIDAHVDTLTEEQASSLLEQSGLSDLYNILNMIFPFYSmyePLSENPGMDPDALRQASQKLDDFLPSALTDAQPN 558
                         570
                  ....*....|.
gi 223468630  600 LNFLLSATVKR 610
Cdd:pfam06419 559 LKKLQSPTLAD 569
COG6 smart01087
Conserved oligomeric complex COG6; COG6 is a component of the conserved oligomeric golgi ...
68-609 0e+00

Conserved oligomeric complex COG6; COG6 is a component of the conserved oligomeric golgi complex, which is composed of eight different subunits and is required for normal golgi morphology and localisation.


Pssm-ID: 215018  Cd Length: 598  Bit Score: 701.77  E-value: 0e+00
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 223468630    68 SLRTRRNLRGDIERKSLAINEEFVSIFKEVKEELESISEDVQAMSNCCQDMTSRLQAAKEQTQDLIVKTTKLQSESQKLE 147
Cdd:smart01087   1 TLEARRNLRSDLEKRLLKINGEFLSEFKPVAEQLQRLSEDVQKLNNSCDSMKDQLNTAKNQTQDLISEASELQEELALLE 80
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 223468630   148 IRAQVADAFLSKFQLTSDEMSLLRGtREGPITEDFFKALGRVKQIHNDVKVLLRTNQQTAGLEIMEQMALLQETAYERLY 227
Cdd:smart01087  81 LKKKLLDAFLSKFTLSQDELDVLTS-REGPIDDEFFQVLDKVQEIHEDCSVLLQNEYQTAGLEIMEKMNQLLERAYERLY 159
                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 223468630   228 RWAQSECRTLTQESCDVSPVLTQAMEALQDRPVLYKYTLDEFGTARRSTVVRGFIDALTRGG--PGGTPRPIEMHSHDPL 305
Cdd:smart01087 160 RWLQSELRNLTTDNPEILSLLRQALRRLSERPVLFKYCLDEFTTARSKSLLDAFLSALTRGGqkPGGNPRPIELSAHDPL 239
                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 223468630   306 RYVGDMLAWLHQATASEKEHLEALLKHVTTQGVEENIQ-------EVVGHITEGVCRPLKVRIEQVIVAEPGAVLLYKIS 378
Cdd:smart01087 240 RYVGDMLAWIHQTIANEKEFLESLFKKVTKQGIEENLQdledldnKLLDRILEGLCRPLRIRIEQVLQSEEGAIILYKIA 319
                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 223468630   379 NLLKFYHHTISgIVGNSATALLTTIEEMHLLSKKIFFNSLSLHASKLMDK-VELPPPDLGPSSALNQTLMLLREVLASHD 457
Cdd:smart01087 320 NLLEFYRMTFS-KGIGDDSQLVRTLGELEDLSKSKFINSLEDQLSGLLRSnLEPPPDDLLPPEWLTDYLSLLKELLDIYE 398
                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 223468630   458 SSVVPLDARQADFVQVLSCVLDPLLQMCTVSASNLGTADMA-TFMVNSLYMMKTTLALFEFTDRRLEMLQFQIEAHLDTL 536
Cdd:smart01087 399 ASLVPLDEREEDFAKVLSKLLDPPLQMCQLSAELLKSPDAKlIFMINCLDLIKSTLSPYEFSDKRLEMLQAQIEAHLDTL 478
                          490       500       510       520       530       540       550
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 223468630   537 INEQASYVLTRVGLSYIYNTVQQHKPEQGSLANMPNLDSVTLKAAMVQFDRYLSAPDNLLIPQLNFLLSATVK 609
Cdd:smart01087 479 TNLQASSLLERTGLSSYYNIINDSPDDKGDLSMYPALDPNSLMSAIQKLDDYLPSALSDVQPNLLKLTSPSIA 551
 
Name Accession Description Interval E-value
COG6 pfam06419
Conserved oligomeric complex COG6; COG6 is a component of the conserved oligomeric golgi ...
56-610 0e+00

Conserved oligomeric complex COG6; COG6 is a component of the conserved oligomeric golgi complex, which is composed of eight different subunits and is required for normal golgi morphology and localization.


Pssm-ID: 461904  Cd Length: 611  Bit Score: 712.07  E-value: 0e+00
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 223468630   56 ALKALSTFFVENSLRTRRNLRGDIERKSLAINEEFVSIFKEVKEELESISEDVQAMSNCCQDMTSRLQAAKEQTQDLIVK 135
Cdd:pfam06419   1 ALGSLSEFYTENTAETRRNLRSDIEKELLKINGEFLKEFGPVVEQLKRIETDVEKLNNSCDEMRKRLSAAKEDTAPLLEE 80
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 223468630  136 TTKLQSESQKLEIRAQVADAFLSKFQLTSDEMSLLRGTREgPITEDFFKALGRVKQIHNDVKVLLRTNQQTAGLEIMEQM 215
Cdd:pfam06419  81 ASSLQEQKKKIELKQKLLDAFLDKFTLSEEEEAALTSGEE-PVNDEFFKALAKVKKIHEDCKILLGTENQRAGLEIMEQM 159
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 223468630  216 ALLQETAYERLYRWAQSECRTLTQESCDVSPVLTQAMEALQDRPVLYKYTLDEFGTARRSTVVRGFIDALTRGGPGGTPR 295
Cdd:pfam06419 160 NKYLEAAFEKLYRWTQREFKNLYLENPEISSLLRKALRVLSERPVLFKYCLDEFAEARSKILSDEFISALTRGGPGGSPR 239
                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 223468630  296 PIEMHSHDPLRYVGDMLAWLHQATASEKEHLEALLKHVT--------TQGVEEN----IQEVVGHITEGVCRPLKVRIEQ 363
Cdd:pfam06419 240 PIELSAHDPLRYVGDMLAWVHSAIASEREFLESLFKFCDgdeiakgiQAGNDSElwslIKELLDRILEGVCRPLKQRVEQ 319
                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 223468630  364 VIVAEPGAVLLYKISNLLKFYHHTISGIVGNSAtALLTTIEEMHLLSKKIFFNSLSLHASKLMDKVELPPPDLGPSSALN 443
Cdd:pfam06419 320 VIQSEEDPITLYKIANLLEFYRSMFSKLLGQDS-SLVETLRELEDSAKRKFFSLLRDHLAKLLREPETPPSDLSPPEWLI 398
                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 223468630  444 QTLMLLREVLASHDSSVVP-LDARQADFVQVLSCVLDPLLQMCTVSASNLGTADMATFMVNSLYMMKTTLALFEFTDRRL 522
Cdd:pfam06419 399 DALSLLLELLDTYETSLASeASEREADFKPILSEILDPLLQMCEPSAKKLPKPDMAIFLINCLDLIQSTLSPYSFASDRV 478
                         490       500       510       520       530       540       550       560
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 223468630  523 EMLQFQIEAHLDTLINEQASYVLTRVGLSYIYNTVQQHKPEQG---SLANMPNLDSVTLKAAMVQFDRYLSAPDNLLIPQ 599
Cdd:pfam06419 479 EELQAQIDAHVDTLTEEQASSLLEQSGLSDLYNILNMIFPFYSmyePLSENPGMDPDALRQASQKLDDFLPSALTDAQPN 558
                         570
                  ....*....|.
gi 223468630  600 LNFLLSATVKR 610
Cdd:pfam06419 559 LKKLQSPTLAD 569
COG6 smart01087
Conserved oligomeric complex COG6; COG6 is a component of the conserved oligomeric golgi ...
68-609 0e+00

Conserved oligomeric complex COG6; COG6 is a component of the conserved oligomeric golgi complex, which is composed of eight different subunits and is required for normal golgi morphology and localisation.


Pssm-ID: 215018  Cd Length: 598  Bit Score: 701.77  E-value: 0e+00
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 223468630    68 SLRTRRNLRGDIERKSLAINEEFVSIFKEVKEELESISEDVQAMSNCCQDMTSRLQAAKEQTQDLIVKTTKLQSESQKLE 147
Cdd:smart01087   1 TLEARRNLRSDLEKRLLKINGEFLSEFKPVAEQLQRLSEDVQKLNNSCDSMKDQLNTAKNQTQDLISEASELQEELALLE 80
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 223468630   148 IRAQVADAFLSKFQLTSDEMSLLRGtREGPITEDFFKALGRVKQIHNDVKVLLRTNQQTAGLEIMEQMALLQETAYERLY 227
Cdd:smart01087  81 LKKKLLDAFLSKFTLSQDELDVLTS-REGPIDDEFFQVLDKVQEIHEDCSVLLQNEYQTAGLEIMEKMNQLLERAYERLY 159
                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 223468630   228 RWAQSECRTLTQESCDVSPVLTQAMEALQDRPVLYKYTLDEFGTARRSTVVRGFIDALTRGG--PGGTPRPIEMHSHDPL 305
Cdd:smart01087 160 RWLQSELRNLTTDNPEILSLLRQALRRLSERPVLFKYCLDEFTTARSKSLLDAFLSALTRGGqkPGGNPRPIELSAHDPL 239
                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 223468630   306 RYVGDMLAWLHQATASEKEHLEALLKHVTTQGVEENIQ-------EVVGHITEGVCRPLKVRIEQVIVAEPGAVLLYKIS 378
Cdd:smart01087 240 RYVGDMLAWIHQTIANEKEFLESLFKKVTKQGIEENLQdledldnKLLDRILEGLCRPLRIRIEQVLQSEEGAIILYKIA 319
                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 223468630   379 NLLKFYHHTISgIVGNSATALLTTIEEMHLLSKKIFFNSLSLHASKLMDK-VELPPPDLGPSSALNQTLMLLREVLASHD 457
Cdd:smart01087 320 NLLEFYRMTFS-KGIGDDSQLVRTLGELEDLSKSKFINSLEDQLSGLLRSnLEPPPDDLLPPEWLTDYLSLLKELLDIYE 398
                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 223468630   458 SSVVPLDARQADFVQVLSCVLDPLLQMCTVSASNLGTADMA-TFMVNSLYMMKTTLALFEFTDRRLEMLQFQIEAHLDTL 536
Cdd:smart01087 399 ASLVPLDEREEDFAKVLSKLLDPPLQMCQLSAELLKSPDAKlIFMINCLDLIKSTLSPYEFSDKRLEMLQAQIEAHLDTL 478
                          490       500       510       520       530       540       550
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 223468630   537 INEQASYVLTRVGLSYIYNTVQQHKPEQGSLANMPNLDSVTLKAAMVQFDRYLSAPDNLLIPQLNFLLSATVK 609
Cdd:smart01087 479 TNLQASSLLERTGLSSYYNIINDSPDDKGDLSMYPALDPNSLMSAIQKLDDYLPSALSDVQPNLLKLTSPSIA 551
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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