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Conserved domains on  [gi|224028279|ref|NP_001138888|]
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transmembrane protein 205 [Homo sapiens]

Protein Classification

DUF4149 domain-containing protein( domain architecture ID 10615278)

DUF4149 domain-containing protein similar to human transmembrane protein 205 (TMEM205) that plays a role in resistance to the chemotherapeutic agent cisplatin in cancer cells

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
DUF4149 pfam13664
Domain of unknown function (DUF4149);
17-114 4.64e-23

Domain of unknown function (DUF4149);


:

Pssm-ID: 463949  Cd Length: 102  Bit Score: 88.08  E-value: 4.64e-23
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 224028279   17 LVLSGAWGMQMWVTFVSGFLLFRSLPRHTFGLVQSKLFPFYFHISMGCAFINLCILASQHaWAQLTFWEASQLYLLFLSL 96
Cdd:pfam13664   1 LLLALWLGGQVFVGFVVAPVLFRALPRHQFGALQSKLFPVYFWLGLALAVLLLLTEPLRG-SGLLGAAERAQLLLLAVML 79

                          90
                  ....*....|....*...
gi 224028279   97 TLATVNARWLEPRTTAAM 114
Cdd:pfam13664  80 LLTLLNLFYLGPRITALM 97
 
Name Accession Description Interval E-value
DUF4149 pfam13664
Domain of unknown function (DUF4149);
17-114 4.64e-23

Domain of unknown function (DUF4149);


Pssm-ID: 463949  Cd Length: 102  Bit Score: 88.08  E-value: 4.64e-23
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 224028279   17 LVLSGAWGMQMWVTFVSGFLLFRSLPRHTFGLVQSKLFPFYFHISMGCAFINLCILASQHaWAQLTFWEASQLYLLFLSL 96
Cdd:pfam13664   1 LLLALWLGGQVFVGFVVAPVLFRALPRHQFGALQSKLFPVYFWLGLALAVLLLLTEPLRG-SGLLGAAERAQLLLLAVML 79

                          90
                  ....*....|....*...
gi 224028279   97 TLATVNARWLEPRTTAAM 114
Cdd:pfam13664  80 LLTLLNLFYLGPRITALM 97
 
Name Accession Description Interval E-value
DUF4149 pfam13664
Domain of unknown function (DUF4149);
17-114 4.64e-23

Domain of unknown function (DUF4149);


Pssm-ID: 463949  Cd Length: 102  Bit Score: 88.08  E-value: 4.64e-23
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 224028279   17 LVLSGAWGMQMWVTFVSGFLLFRSLPRHTFGLVQSKLFPFYFHISMGCAFINLCILASQHaWAQLTFWEASQLYLLFLSL 96
Cdd:pfam13664   1 LLLALWLGGQVFVGFVVAPVLFRALPRHQFGALQSKLFPVYFWLGLALAVLLLLTEPLRG-SGLLGAAERAQLLLLAVML 79

                          90
                  ....*....|....*...
gi 224028279   97 TLATVNARWLEPRTTAAM 114
Cdd:pfam13664  80 LLTLLNLFYLGPRITALM 97
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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