|
Name |
Accession |
Description |
Interval |
E-value |
| TrmA |
COG2265 |
tRNA/tmRNA/rRNA uracil-C5-methylase, TrmA/RlmC/RlmD family [Translation, ribosomal structure ... |
83-492 |
8.78e-64 |
|
tRNA/tmRNA/rRNA uracil-C5-methylase, TrmA/RlmC/RlmD family [Translation, ribosomal structure and biogenesis]; tRNA/tmRNA/rRNA uracil-C5-methylase, TrmA/RlmC/RlmD family is part of the Pathway/BioSystem: tRNA modification
Pssm-ID: 441866 [Multi-domain] Cd Length: 377 Bit Score: 211.57 E-value: 8.78e-64
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 269784756 83 LSYEAQLKVKfeaQKKLLQSLESHlkvlhGVSDTVAahqseglrclLHPIIPSPTTTGYRNKSTFSVYRSpDGNPkTVGY 162
Cdd:COG2265 81 LSYEAQLELK---QRVVREALERI-----GGLPEVE----------VEPIIGSPEPWGYRNRARLSVRRT-DGRL-RLGF 140
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 269784756 163 YlgtwkdgnvvclpcnhlknipEKHSqvaqyYEVFlrqsSVEPCLLFHEgghwrelvvrtnrqgHTMAIVTfhpqglsee 242
Cdd:COG2265 141 Y---------------------ARGS-----HELV----DIDECPLLDP---------------ALNALLP--------- 166
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 269784756 243 evcvqkvTLKDFFTKGPGAICELTSLyfqestMTRCshqqspyqllfGEPHIFEDLLGLKIRISPDAFFQINTAGAEMLY 322
Cdd:COG2265 167 -------ALRELLAELGARRGELRHL------VVRA-----------GRDYLTERLGGLTFRISPGSFFQVNPEQAEALY 222
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 269784756 323 RIIGELSGVNSESLLLDICCGTGVIGLSVAQRASQVHGIELVEQAVEDARWTAAFNGVTNCEFHAGRAETILPQLLksqK 402
Cdd:COG2265 223 AAALEWLDLTGGERVLDLYCGVGTFALPLARRAKKVIGVEIVPEAVEDARENARLNGLKNVEFVAGDLEEVLPELL---W 299
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 269784756 403 DEKLTVAVVNPARAGLHYRVVRAIRNCRtIHTLVFVSCKPhgeST--RNfielccppnsAKQLLGDPFVLREAVPVDLFP 480
Cdd:COG2265 300 GGRPDVVVLDPPRAGAGPEVLEALAALG-PRRIVYVSCNP---ATlaRD----------LALLVEGGYRLEKVQPVDMFP 365
|
410
....*....|..
gi 269784756 481 HTPHCELVLLFT 492
Cdd:COG2265 366 HTHHVESVALLE 377
|
|
| rumA |
TIGR00479 |
23S rRNA (uracil-5-)-methyltransferase RumA; This protein family was first proposed to be RNA ... |
83-486 |
2.99e-35 |
|
23S rRNA (uracil-5-)-methyltransferase RumA; This protein family was first proposed to be RNA methyltransferases by homology to the TrmA family. The member from E. coli has now been shown to act as the 23S RNA methyltransferase for the conserved U1939. The gene is now designated rumA and was previously designated ygcA. [Protein synthesis, tRNA and rRNA base modification]
Pssm-ID: 129571 [Multi-domain] Cd Length: 431 Bit Score: 136.49 E-value: 2.99e-35
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 269784756 83 LSYEAQLKVKfeaQKKLLQSLESHLKVlhgvsdtvaahQSEGLRclLHPIIPSpTTTGYRNKSTFSVYRSPDGNPKTVGY 162
Cdd:TIGR00479 72 LSYELQLRSK---QQQVIALLERIGKF-----------VSEPIE--DVPTIGD-DPWGYRNKARLSLGRSPSGQLQAGFY 134
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 269784756 163 YLGTWKDGNVVCLPCNH---------LKNIPEKHSQVAQYYEVflrqssvepcllfhEGGHWRELVVRTNRQGHTMAIV- 232
Cdd:TIGR00479 135 QKGSHDIVDVKQCPVQApalnallpkVRAILENFGASRYLEHK--------------ELGQARHGVLRIGRHTGELSSVd 200
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 269784756 233 -TFHpQGLSEEEVCVQKVTlKDFftKGPGAIC-----ELTSLYFQESTMTrcshqqspyqlLFGEPHIFEDLLGLKIRIS 306
Cdd:TIGR00479 201 rTAL-ERFPHKEELDLYLQ-PDS--PDVKSICqninpEKTNVIFGEETEV-----------IAGEMPIYDKSGDLSFTFS 265
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 269784756 307 PDAFFQINTAGAEMLYRIIGELSGVNSESLLLDICCGTGVIGLSVAQRASQVHGIELVEQAVEDARWTAAFNGVTNCEFH 386
Cdd:TIGR00479 266 ARDFIQVNSGQNEKLVDRALEWLELQGEERVLDAYCGMGTFTLPLAKQAKSVVGVEGVPESVEKAQQNAELNGIANVTFY 345
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 269784756 387 AGRAETILPQLlkSQKDEKLTVAVVNPARAGLHYRVVRAIRNCRTIHtLVFVSCKPhGESTRNfielccppnsAKQLLGD 466
Cdd:TIGR00479 346 HGTLETVLPKQ--PWAGNGFDKVLLDPPRKGCAAGVLRTIIKLKPER-IVYVSCNP-ATLARD----------LEALCKA 411
|
410 420
....*....|....*....|
gi 269784756 467 PFVLREAVPVDLFPHTPHCE 486
Cdd:TIGR00479 412 GYTIARVQPVDMFPHTGHVE 431
|
|
| rumB |
PRK03522 |
23S rRNA (uracil(747)-C(5))-methyltransferase RlmC; |
290-490 |
1.06e-16 |
|
23S rRNA (uracil(747)-C(5))-methyltransferase RlmC;
Pssm-ID: 235128 [Multi-domain] Cd Length: 315 Bit Score: 80.68 E-value: 1.06e-16
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 269784756 290 GEPHIF--------EDLLGLKIRISPDAFFQINTAGAEMLYRI----IGELsGVNSeslLLDICCGTGVIGLSVAQRASQ 357
Cdd:PRK03522 122 GEEEIFlteqqalpERFNGVPLFIRPQSFFQTNPAVAAQLYATardwVREL-PPRS---MWDLFCGVGGFGLHCATPGMQ 197
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 269784756 358 VHGIELVEQAVEDARWTAAFNGVTNCEFHAGRAETILpqllkSQKDEKLTVAVVNPARAGLHYRVVRAIrNCRTIHTLVF 437
Cdd:PRK03522 198 LTGIEISAEAIACAKQSAAELGLTNVQFQALDSTQFA-----TAQGEVPDLVLVNPPRRGIGKELCDYL-SQMAPRFILY 271
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|....*
gi 269784756 438 VSCKPHgestrnfielccppNSAKQLLGDP-FVLREAVPVDLFPHTPHCE-LVLL 490
Cdd:PRK03522 272 SSCNAQ--------------TMAKDLAHLPgYRIERVQLFDMFPHTAHYEvLTLL 312
|
|
| Methyltransf_25 |
pfam13649 |
Methyltransferase domain; This family appears to be a methyltransferase domain. |
338-430 |
2.01e-08 |
|
Methyltransferase domain; This family appears to be a methyltransferase domain.
Pssm-ID: 463945 [Multi-domain] Cd Length: 96 Bit Score: 51.80 E-value: 2.01e-08
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 269784756 338 LDICCGTGVIGLSVAQRA-SQVHGIELVEQAVEDARWTAAFNGVtNCEFHAGRAETIlpqllkSQKDEKLTVAVvnpARA 416
Cdd:pfam13649 2 LDLGCGTGRLTLALARRGgARVTGVDLSPEMLERARERAAEAGL-NVEFVQGDAEDL------PFPDGSFDLVV---SSG 71
|
90
....*....|....*...
gi 269784756 417 GLHY----RVVRAIRNCR 430
Cdd:pfam13649 72 VLHHlpdpDLEAALREIA 89
|
|
| AdoMet_MTases |
cd02440 |
S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I; ... |
337-430 |
2.17e-08 |
|
S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I; AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy). There are at least five structurally distinct families of AdoMet-MTases, class I being the largest and most diverse. Within this class enzymes can be classified by different substrate specificities (small molecules, lipids, nucleic acids, etc.) and different target atoms for methylation (nitrogen, oxygen, carbon, sulfur, etc.).
Pssm-ID: 100107 [Multi-domain] Cd Length: 107 Bit Score: 52.05 E-value: 2.17e-08
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 269784756 337 LLDICCGTGVIGLSVAQR-ASQVHGIELVEQAVEDARWTAAFNGVTNCEFHAGRAETILPqllksQKDEKLTVAVVNPAR 415
Cdd:cd02440 2 VLDLGCGTGALALALASGpGARVTGVDISPVALELARKAAAALLADNVEVLKGDAEELPP-----EADESFDVIISDPPL 76
|
90
....*....|....*
gi 269784756 416 AGLHYRVVRAIRNCR 430
Cdd:cd02440 77 HHLVEDLARFLEEAR 91
|
|
| |
|
Name |
Accession |
Description |
Interval |
E-value |
| TrmA |
COG2265 |
tRNA/tmRNA/rRNA uracil-C5-methylase, TrmA/RlmC/RlmD family [Translation, ribosomal structure ... |
83-492 |
8.78e-64 |
|
tRNA/tmRNA/rRNA uracil-C5-methylase, TrmA/RlmC/RlmD family [Translation, ribosomal structure and biogenesis]; tRNA/tmRNA/rRNA uracil-C5-methylase, TrmA/RlmC/RlmD family is part of the Pathway/BioSystem: tRNA modification
Pssm-ID: 441866 [Multi-domain] Cd Length: 377 Bit Score: 211.57 E-value: 8.78e-64
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 269784756 83 LSYEAQLKVKfeaQKKLLQSLESHlkvlhGVSDTVAahqseglrclLHPIIPSPTTTGYRNKSTFSVYRSpDGNPkTVGY 162
Cdd:COG2265 81 LSYEAQLELK---QRVVREALERI-----GGLPEVE----------VEPIIGSPEPWGYRNRARLSVRRT-DGRL-RLGF 140
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 269784756 163 YlgtwkdgnvvclpcnhlknipEKHSqvaqyYEVFlrqsSVEPCLLFHEgghwrelvvrtnrqgHTMAIVTfhpqglsee 242
Cdd:COG2265 141 Y---------------------ARGS-----HELV----DIDECPLLDP---------------ALNALLP--------- 166
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 269784756 243 evcvqkvTLKDFFTKGPGAICELTSLyfqestMTRCshqqspyqllfGEPHIFEDLLGLKIRISPDAFFQINTAGAEMLY 322
Cdd:COG2265 167 -------ALRELLAELGARRGELRHL------VVRA-----------GRDYLTERLGGLTFRISPGSFFQVNPEQAEALY 222
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 269784756 323 RIIGELSGVNSESLLLDICCGTGVIGLSVAQRASQVHGIELVEQAVEDARWTAAFNGVTNCEFHAGRAETILPQLLksqK 402
Cdd:COG2265 223 AAALEWLDLTGGERVLDLYCGVGTFALPLARRAKKVIGVEIVPEAVEDARENARLNGLKNVEFVAGDLEEVLPELL---W 299
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 269784756 403 DEKLTVAVVNPARAGLHYRVVRAIRNCRtIHTLVFVSCKPhgeST--RNfielccppnsAKQLLGDPFVLREAVPVDLFP 480
Cdd:COG2265 300 GGRPDVVVLDPPRAGAGPEVLEALAALG-PRRIVYVSCNP---ATlaRD----------LALLVEGGYRLEKVQPVDMFP 365
|
410
....*....|..
gi 269784756 481 HTPHCELVLLFT 492
Cdd:COG2265 366 HTHHVESVALLE 377
|
|
| rumA |
TIGR00479 |
23S rRNA (uracil-5-)-methyltransferase RumA; This protein family was first proposed to be RNA ... |
83-486 |
2.99e-35 |
|
23S rRNA (uracil-5-)-methyltransferase RumA; This protein family was first proposed to be RNA methyltransferases by homology to the TrmA family. The member from E. coli has now been shown to act as the 23S RNA methyltransferase for the conserved U1939. The gene is now designated rumA and was previously designated ygcA. [Protein synthesis, tRNA and rRNA base modification]
Pssm-ID: 129571 [Multi-domain] Cd Length: 431 Bit Score: 136.49 E-value: 2.99e-35
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 269784756 83 LSYEAQLKVKfeaQKKLLQSLESHLKVlhgvsdtvaahQSEGLRclLHPIIPSpTTTGYRNKSTFSVYRSPDGNPKTVGY 162
Cdd:TIGR00479 72 LSYELQLRSK---QQQVIALLERIGKF-----------VSEPIE--DVPTIGD-DPWGYRNKARLSLGRSPSGQLQAGFY 134
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 269784756 163 YLGTWKDGNVVCLPCNH---------LKNIPEKHSQVAQYYEVflrqssvepcllfhEGGHWRELVVRTNRQGHTMAIV- 232
Cdd:TIGR00479 135 QKGSHDIVDVKQCPVQApalnallpkVRAILENFGASRYLEHK--------------ELGQARHGVLRIGRHTGELSSVd 200
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 269784756 233 -TFHpQGLSEEEVCVQKVTlKDFftKGPGAIC-----ELTSLYFQESTMTrcshqqspyqlLFGEPHIFEDLLGLKIRIS 306
Cdd:TIGR00479 201 rTAL-ERFPHKEELDLYLQ-PDS--PDVKSICqninpEKTNVIFGEETEV-----------IAGEMPIYDKSGDLSFTFS 265
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 269784756 307 PDAFFQINTAGAEMLYRIIGELSGVNSESLLLDICCGTGVIGLSVAQRASQVHGIELVEQAVEDARWTAAFNGVTNCEFH 386
Cdd:TIGR00479 266 ARDFIQVNSGQNEKLVDRALEWLELQGEERVLDAYCGMGTFTLPLAKQAKSVVGVEGVPESVEKAQQNAELNGIANVTFY 345
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 269784756 387 AGRAETILPQLlkSQKDEKLTVAVVNPARAGLHYRVVRAIRNCRTIHtLVFVSCKPhGESTRNfielccppnsAKQLLGD 466
Cdd:TIGR00479 346 HGTLETVLPKQ--PWAGNGFDKVLLDPPRKGCAAGVLRTIIKLKPER-IVYVSCNP-ATLARD----------LEALCKA 411
|
410 420
....*....|....*....|
gi 269784756 467 PFVLREAVPVDLFPHTPHCE 486
Cdd:TIGR00479 412 GYTIARVQPVDMFPHTGHVE 431
|
|
| rumB |
PRK03522 |
23S rRNA (uracil(747)-C(5))-methyltransferase RlmC; |
290-490 |
1.06e-16 |
|
23S rRNA (uracil(747)-C(5))-methyltransferase RlmC;
Pssm-ID: 235128 [Multi-domain] Cd Length: 315 Bit Score: 80.68 E-value: 1.06e-16
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 269784756 290 GEPHIF--------EDLLGLKIRISPDAFFQINTAGAEMLYRI----IGELsGVNSeslLLDICCGTGVIGLSVAQRASQ 357
Cdd:PRK03522 122 GEEEIFlteqqalpERFNGVPLFIRPQSFFQTNPAVAAQLYATardwVREL-PPRS---MWDLFCGVGGFGLHCATPGMQ 197
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 269784756 358 VHGIELVEQAVEDARWTAAFNGVTNCEFHAGRAETILpqllkSQKDEKLTVAVVNPARAGLHYRVVRAIrNCRTIHTLVF 437
Cdd:PRK03522 198 LTGIEISAEAIACAKQSAAELGLTNVQFQALDSTQFA-----TAQGEVPDLVLVNPPRRGIGKELCDYL-SQMAPRFILY 271
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|....*
gi 269784756 438 VSCKPHgestrnfielccppNSAKQLLGDP-FVLREAVPVDLFPHTPHCE-LVLL 490
Cdd:PRK03522 272 SSCNAQ--------------TMAKDLAHLPgYRIERVQLFDMFPHTAHYEvLTLL 312
|
|
| RsmC |
COG2813 |
16S rRNA G1207 methylase RsmC [Translation, ribosomal structure and biogenesis]; 16S rRNA ... |
337-426 |
1.04e-11 |
|
16S rRNA G1207 methylase RsmC [Translation, ribosomal structure and biogenesis]; 16S rRNA G1207 methylase RsmC is part of the Pathway/BioSystem: 16S rRNA modification
Pssm-ID: 442062 [Multi-domain] Cd Length: 191 Bit Score: 63.67 E-value: 1.04e-11
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 269784756 337 LLDICCGTGVIGLSVAQRA--SQVHGIELVEQAVEDARWTAAFNGVTNCEFHAgraetilPQLLKSQKDEKLTVAVVN-P 413
Cdd:COG2813 53 VLDLGCGYGVIGLALAKRNpeARVTLVDVNARAVELARANAAANGLENVEVLW-------SDGLSGVPDGSFDLILSNpP 125
|
90
....*....|....*
gi 269784756 414 ARAGL--HYRVVRAI 426
Cdd:COG2813 126 FHAGRavDKEVAHAL 140
|
|
| TrmN6 |
COG4123 |
tRNA1(Val) A37 N6-methylase TrmN6 [Translation, ribosomal structure and biogenesis]; tRNA1(Val) ... |
337-413 |
1.41e-09 |
|
tRNA1(Val) A37 N6-methylase TrmN6 [Translation, ribosomal structure and biogenesis]; tRNA1(Val) A37 N6-methylase TrmN6 is part of the Pathway/BioSystem: tRNA modification
Pssm-ID: 443299 [Multi-domain] Cd Length: 238 Bit Score: 58.23 E-value: 1.41e-09
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 269784756 337 LLDICCGTGVIGLSVAQR--ASQVHGIELVEQAVEDARWTAAFNGVTN-CEFHAGRaetiLPQLLKSQKDEKLTVAVVNP 413
Cdd:COG4123 41 VLDLGTGTGVIALMLAQRspGARITGVEIQPEAAELARRNVALNGLEDrITVIHGD----LKEFAAELPPGSFDLVVSNP 116
|
|
| Methyltransf_25 |
pfam13649 |
Methyltransferase domain; This family appears to be a methyltransferase domain. |
338-430 |
2.01e-08 |
|
Methyltransferase domain; This family appears to be a methyltransferase domain.
Pssm-ID: 463945 [Multi-domain] Cd Length: 96 Bit Score: 51.80 E-value: 2.01e-08
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 269784756 338 LDICCGTGVIGLSVAQRA-SQVHGIELVEQAVEDARWTAAFNGVtNCEFHAGRAETIlpqllkSQKDEKLTVAVvnpARA 416
Cdd:pfam13649 2 LDLGCGTGRLTLALARRGgARVTGVDLSPEMLERARERAAEAGL-NVEFVQGDAEDL------PFPDGSFDLVV---SSG 71
|
90
....*....|....*...
gi 269784756 417 GLHY----RVVRAIRNCR 430
Cdd:pfam13649 72 VLHHlpdpDLEAALREIA 89
|
|
| AdoMet_MTases |
cd02440 |
S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I; ... |
337-430 |
2.17e-08 |
|
S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I; AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy). There are at least five structurally distinct families of AdoMet-MTases, class I being the largest and most diverse. Within this class enzymes can be classified by different substrate specificities (small molecules, lipids, nucleic acids, etc.) and different target atoms for methylation (nitrogen, oxygen, carbon, sulfur, etc.).
Pssm-ID: 100107 [Multi-domain] Cd Length: 107 Bit Score: 52.05 E-value: 2.17e-08
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 269784756 337 LLDICCGTGVIGLSVAQR-ASQVHGIELVEQAVEDARWTAAFNGVTNCEFHAGRAETILPqllksQKDEKLTVAVVNPAR 415
Cdd:cd02440 2 VLDLGCGTGALALALASGpGARVTGVDISPVALELARKAAAALLADNVEVLKGDAEELPP-----EADESFDVIISDPPL 76
|
90
....*....|....*
gi 269784756 416 AGLHYRVVRAIRNCR 430
Cdd:cd02440 77 HHLVEDLARFLEEAR 91
|
|
| MTS |
pfam05175 |
Methyltransferase small domain; This domain is found in ribosomal RNA small subunit ... |
338-426 |
2.86e-08 |
|
Methyltransferase small domain; This domain is found in ribosomal RNA small subunit methyltransferase C as well as other methyltransferases.
Pssm-ID: 428349 [Multi-domain] Cd Length: 170 Bit Score: 53.36 E-value: 2.86e-08
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 269784756 338 LDICCGTGVIGLSVAQRASQVHgIELVE---QAVEDARWTAAFNGVTNCEFHAGraetilpQLLKSQKDEKLTVAVVNPA 414
Cdd:pfam05175 36 LDLGCGAGVLGAALAKESPDAE-LTMVDinaRALESARENLAANGLENGEVVAS-------DVYSGVEDGKFDLIISNPP 107
|
90
....*....|....*
gi 269784756 415 -RAGLH--YRVVRAI 426
Cdd:pfam05175 108 fHAGLAttYNVAQRF 122
|
|
| Methyltransf_31 |
pfam13847 |
Methyltransferase domain; This family appears to have methyltransferase activity. |
337-402 |
2.95e-08 |
|
Methyltransferase domain; This family appears to have methyltransferase activity.
Pssm-ID: 463998 [Multi-domain] Cd Length: 150 Bit Score: 52.80 E-value: 2.95e-08
10 20 30 40 50 60
....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 269784756 337 LLDICCGTGVIGLSVAQRA---SQVHGIELVEQAVEDARWTAAFNGVTNCEFHAGRAETiLPQLLKSQK 402
Cdd:pfam13847 7 VLDLGCGTGHLSFELAEELgpnAEVVGIDISEEAIEKARENAQKLGFDNVEFEQGDIEE-LPELLEDDK 74
|
|
| tRNA_U5-meth_tr |
pfam05958 |
tRNA (Uracil-5-)-methyltransferase; This family consists of (Uracil-5-)-methyltransferases EC: ... |
308-493 |
1.58e-07 |
|
tRNA (Uracil-5-)-methyltransferase; This family consists of (Uracil-5-)-methyltransferases EC:2.1.1.35 from bacteria, archaea and eukaryotes. A 5-methyluridine (m(5)U) residue at position 54 is a conserved feature of bacterial and eukaryotic tRNAs. The methylation of U54 is catalyzed by the tRNA(m5U54)methyltransferase, which in Saccharomyces cerevisiae is encoded by the nonessential TRM2 gene. It is thought that tRNA modification enzymes might have a role in tRNA maturation not necessarily linked to their known catalytic activity.
Pssm-ID: 428692 Cd Length: 357 Bit Score: 53.21 E-value: 1.58e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 269784756 308 DAFFQINTAGAE-ML---YRIIGelsgvNSESLLLDICCGTGVIGLSVAQRASQVHGIELVEQAVEDARWTAAFNGVTNC 383
Cdd:pfam05958 177 NSFTQPNAAVNIkMLewaCDVTQ-----GSKGDLLELYCGNGNFSLALARNFRKVLATEIAKPSVAAAQYNIAANNIDNV 251
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 269784756 384 EFHAGRAETiLPQLLKSQ-----------KDEKLTVAVVNPARAGLHYRVVRAIRNCRTIhtlVFVSCKPHgestrnfiE 452
Cdd:pfam05958 252 QIIRMSAEE-FTQAMNGVrefnrlkgidlKSYNCSTIFVDPPRAGLDPETLKLVQAYPRI---LYISCNPE--------T 319
|
170 180 190 200
....*....|....*....|....*....|....*....|.
gi 269784756 453 LCcppNSAKQLLGDPFVLREAVpVDLFPHTPHCELVLLFTR 493
Cdd:pfam05958 320 LC---ANLEQLSKTHRVERFAL-FDQFPYTHHMECGVLLEK 356
|
|
| PRK09328 |
PRK09328 |
N5-glutamine S-adenosyl-L-methionine-dependent methyltransferase; Provisional |
338-413 |
7.59e-07 |
|
N5-glutamine S-adenosyl-L-methionine-dependent methyltransferase; Provisional
Pssm-ID: 236467 [Multi-domain] Cd Length: 275 Bit Score: 50.55 E-value: 7.59e-07
10 20 30 40 50 60 70
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 269784756 338 LDICCGTGVIGLSVAQR--ASQVHGIELVEQAVEDARWTAAFNGVTNCEFHAGRaetilpqLLKSQKDEKLTVAVVNP 413
Cdd:PRK09328 113 LDLGTGSGAIALALAKErpDAEVTAVDISPEALAVARRNAKHGLGARVEFLQGD-------WFEPLPGGRFDLIVSNP 183
|
|
| UbiE |
COG2226 |
Ubiquinone/menaquinone biosynthesis C-methylase UbiE/MenG [Coenzyme transport and metabolism]; ... |
337-393 |
1.34e-06 |
|
Ubiquinone/menaquinone biosynthesis C-methylase UbiE/MenG [Coenzyme transport and metabolism]; Ubiquinone/menaquinone biosynthesis C-methylase UbiE/MenG is part of the Pathway/BioSystem: Biotin biosynthesis
Pssm-ID: 441828 [Multi-domain] Cd Length: 143 Bit Score: 47.68 E-value: 1.34e-06
10 20 30 40 50
....*....|....*....|....*....|....*....|....*....|....*..
gi 269784756 337 LLDICCGTGVIGLSVAQRASQVHGIELVEQAVEDARWTAAFNGVtNCEFHAGRAETI 393
Cdd:COG2226 26 VLDLGCGTGRLALALAERGARVTGVDISPEMLELARERAAEAGL-NVEFVVGDAEDL 81
|
|
| HemK |
COG2890 |
Methylase of polypeptide chain release factors [Translation, ribosomal structure and ... |
284-388 |
1.81e-06 |
|
Methylase of polypeptide chain release factors [Translation, ribosomal structure and biogenesis];
Pssm-ID: 442135 [Multi-domain] Cd Length: 282 Bit Score: 49.38 E-value: 1.81e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 269784756 284 PYQLLFGEphifEDLLGLKIRISPDAFfqI---NTAgaEMLYRIIGELSGvNSESLLLDICCGTGVIGLSVAQR--ASQV 358
Cdd:COG2890 69 PLAYILGE----AEFYGLEFKVDPGVL--IprpETE--ELVELALALLPA-GAPPRVLDLGTGSGAIALALAKErpDARV 139
|
90 100 110
....*....|....*....|....*....|.
gi 269784756 359 HGIELVEQAVEDARWTAAFNGVTN-CEFHAG 388
Cdd:COG2890 140 TAVDISPDALAVARRNAERLGLEDrVRFLQG 170
|
|
| SmtA |
COG0500 |
SAM-dependent methyltransferase [Secondary metabolites biosynthesis, transport and catabolism, ... |
338-395 |
1.20e-05 |
|
SAM-dependent methyltransferase [Secondary metabolites biosynthesis, transport and catabolism, General function prediction only];
Pssm-ID: 440266 [Multi-domain] Cd Length: 199 Bit Score: 46.06 E-value: 1.20e-05
10 20 30 40 50
....*....|....*....|....*....|....*....|....*....|....*....
gi 269784756 338 LDICCGTGVIGLSVAQRA-SQVHGIELVEQAVEDARWTAAFNGVTNCEFHAGRAETILP 395
Cdd:COG0500 31 LDLGCGTGRNLLALAARFgGRVIGIDLSPEAIALARARAAKAGLGNVEFLVADLAELDP 89
|
|
| UbiG |
COG2227 |
2-polyprenyl-3-methyl-5-hydroxy-6-metoxy-1,4-benzoquinol methylase [Coenzyme transport and ... |
337-393 |
1.34e-05 |
|
2-polyprenyl-3-methyl-5-hydroxy-6-metoxy-1,4-benzoquinol methylase [Coenzyme transport and metabolism]; 2-polyprenyl-3-methyl-5-hydroxy-6-metoxy-1,4-benzoquinol methylase is part of the Pathway/BioSystem: Ubiquinone biosynthesis
Pssm-ID: 441829 [Multi-domain] Cd Length: 126 Bit Score: 44.62 E-value: 1.34e-05
10 20 30 40 50
....*....|....*....|....*....|....*....|....*....|....*..
gi 269784756 337 LLDICCGTGVIGLSVAQRASQVHGIELVEQAVEDARWTAAFNGVtncEFHAGRAETI 393
Cdd:COG2227 28 VLDVGCGTGRLALALARRGADVTGVDISPEALEIARERAAELNV---DFVQGDLEDL 81
|
|
| PRK05031 |
PRK05031 |
tRNA (uracil-5-)-methyltransferase; Validated |
308-490 |
6.92e-05 |
|
tRNA (uracil-5-)-methyltransferase; Validated
Pssm-ID: 235332 Cd Length: 362 Bit Score: 44.82 E-value: 6.92e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 269784756 308 DAFFQINTAGAE-MLYRIIGELSgvNSESLLLDICCGTGVIGLSVAQRASQVHGIELVEQAVEDARWTAAFNGVTNCEFH 386
Cdd:PRK05031 182 NSFTQPNAAVNEkMLEWALDATK--GSKGDLLELYCGNGNFTLALARNFRRVLATEISKPSVAAAQYNIAANGIDNVQII 259
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 269784756 387 AGRAETiLPQLLKSQ------KDEKL------TVaVVNPARAGLHYRVVRAIRNCRTIhtlVFVSCKPHgesT--RNFIE 452
Cdd:PRK05031 260 RMSAEE-FTQAMNGVrefnrlKGIDLksynfsTI-FVDPPRAGLDDETLKLVQAYERI---LYISCNPE---TlcENLET 331
|
170 180 190
....*....|....*....|....*....|....*....
gi 269784756 453 LCcppNSAKqllgdpfVLREAVpVDLFPHTPHCEL-VLL 490
Cdd:PRK05031 332 LS---QTHK-------VERFAL-FDQFPYTHHMECgVLL 359
|
|
| Tam |
COG4106 |
Trans-aconitate methyltransferase [Energy production and conversion]; |
338-396 |
7.11e-05 |
|
Trans-aconitate methyltransferase [Energy production and conversion];
Pssm-ID: 443282 [Multi-domain] Cd Length: 100 Bit Score: 41.73 E-value: 7.11e-05
10 20 30 40 50 60
....*....|....*....|....*....|....*....|....*....|....*....|.
gi 269784756 338 LDICCGTGVIGLSVAQR--ASQVHGIELVEQAVEDARwtaafNGVTNCEFHAGRAETILPQ 396
Cdd:COG4106 6 LDLGCGTGRLTALLAERfpGARVTGVDLSPEMLARAR-----ARLPNVRFVVADLRDLDPP 61
|
|
| COG4976 |
COG4976 |
Predicted methyltransferase, contains TPR repeat [General function prediction only]; |
338-372 |
1.71e-04 |
|
Predicted methyltransferase, contains TPR repeat [General function prediction only];
Pssm-ID: 444001 [Multi-domain] Cd Length: 181 Bit Score: 42.29 E-value: 1.71e-04
10 20 30
....*....|....*....|....*....|....*
gi 269784756 338 LDICCGTGVIGLSVAQRASQVHGIELVEQAVEDAR 372
Cdd:COG4976 51 LDLGCGTGLLGEALRPRGYRLTGVDLSEEMLAKAR 85
|
|
| PRK14968 |
PRK14968 |
putative methyltransferase; Provisional |
338-413 |
3.45e-04 |
|
putative methyltransferase; Provisional
Pssm-ID: 237872 [Multi-domain] Cd Length: 188 Bit Score: 41.42 E-value: 3.45e-04
10 20 30 40 50 60 70
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 269784756 338 LDICCGTGVIGLSVAQRASQVHGIELVEQAVEDARWTAAFNGVTNCEFHAGRAEtilpqLLKSQKDEKLTVAVVNP 413
Cdd:PRK14968 28 LEVGTGSGIVAIVAAKNGKKVVGVDINPYAVECAKCNAKLNNIRNNGVEVIRSD-----LFEPFRGDKFDVILFNP 98
|
|
| COG4076 |
COG4076 |
Predicted RNA methylase [General function prediction only]; |
331-396 |
6.76e-04 |
|
Predicted RNA methylase [General function prediction only];
Pssm-ID: 443253 [Multi-domain] Cd Length: 230 Bit Score: 41.18 E-value: 6.76e-04
10 20 30 40 50 60
....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 269784756 331 VNSESLLLDICCGTGVIG-LSVAQRASQVHGIELVEQAVEDARWTAAFNGVT-NCEFHAGRAETILPQ 396
Cdd:COG4076 33 VKPGDVVLDIGTGSGLLSmLAARAGAKKVYAVEVNPDIAAVARRIIAANGLSdRITVINADATDLDLP 100
|
|
| CobL |
COG2242 |
Precorrin-6B methylase 2 [Coenzyme transport and metabolism]; Precorrin-6B methylase 2 is part ... |
335-397 |
8.63e-04 |
|
Precorrin-6B methylase 2 [Coenzyme transport and metabolism]; Precorrin-6B methylase 2 is part of the Pathway/BioSystem: Cobalamine/B12 biosynthesis
Pssm-ID: 441843 [Multi-domain] Cd Length: 403 Bit Score: 41.69 E-value: 8.63e-04
10 20 30 40 50 60
....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 269784756 335 SLLLDICCGTGVIGLSVAQRA--SQVHGIELVEQAVEDARWTA-AFnGVTNCEFHAGRAETILPQL 397
Cdd:COG2242 249 DVLWDIGAGSGSVSIEAARLApgGRVYAIERDPERAALIRANArRF-GVPNVEVVEGEAPEALADL 313
|
|
| Methyltransf_11 |
pfam08241 |
Methyltransferase domain; Members of this family are SAM dependent methyltransferases. |
338-444 |
3.98e-03 |
|
Methyltransferase domain; Members of this family are SAM dependent methyltransferases.
Pssm-ID: 462406 [Multi-domain] Cd Length: 94 Bit Score: 36.49 E-value: 3.98e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 269784756 338 LDICCGTGVIGLSVAQRASQVHGIELVEQAVEDARWTAAFNGVTnceFHAGRAETiLPqllksQKDEKLTVAVvnpARAG 417
Cdd:pfam08241 1 LDVGCGTGLLTELLARLGARVTGVDISPEMLELAREKAPREGLT---FVVGDAED-LP-----FPDNSFDLVL---SSEV 68
|
90 100
....*....|....*....|....*....
gi 269784756 418 LHY--RVVRAIRNCRTIhtlvfvsCKPHG 444
Cdd:pfam08241 69 LHHveDPERALREIARV-------LKPGG 90
|
|
| COG2263 |
COG2263 |
Predicted RNA methylase [General function prediction only]; |
318-372 |
4.69e-03 |
|
Predicted RNA methylase [General function prediction only];
Pssm-ID: 441864 [Multi-domain] Cd Length: 199 Bit Score: 38.35 E-value: 4.69e-03
10 20 30 40 50
....*....|....*....|....*....|....*....|....*....|....*...
gi 269784756 318 AEMLY--RIIGELSGvnseSLLLDICCGTGVIGLSVAQR-ASQVHGIELVEQAVEDAR 372
Cdd:COG2263 32 AELLHlaYLRGDIEG----KTVLDLGCGTGMLAIGAALLgAKKVVGVDIDPEALEIAR 85
|
|
| PrmA |
COG2264 |
Ribosomal protein L11 methylase PrmA [Translation, ribosomal structure and biogenesis]; |
337-402 |
6.66e-03 |
|
Ribosomal protein L11 methylase PrmA [Translation, ribosomal structure and biogenesis];
Pssm-ID: 441865 [Multi-domain] Cd Length: 284 Bit Score: 38.62 E-value: 6.66e-03
10 20 30 40 50 60
....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 269784756 337 LLDICCGTGVigLSVA---QRASQVHGIELVEQAVEDARWTAAFNGVtncefhAGRAETILPQLLKSQK 402
Cdd:COG2264 152 VLDVGCGSGI--LAIAaakLGAKRVLAVDIDPVAVEAARENAELNGV------EDRIEVVLGDLLEDGP 212
|
|
| Trm11 |
COG1041 |
tRNA G10 N-methylase Trm11 [Translation, ribosomal structure and biogenesis]; tRNA G10 ... |
323-413 |
7.25e-03 |
|
tRNA G10 N-methylase Trm11 [Translation, ribosomal structure and biogenesis]; tRNA G10 N-methylase Trm11 is part of the Pathway/BioSystem: tRNA modification
Pssm-ID: 440663 [Multi-domain] Cd Length: 172 Bit Score: 37.62 E-value: 7.25e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 269784756 323 RIIGELSGVNSESLLLDICCGTGVIGLSVAQRASQVHGIELVEQAVEDARWTAAFNGVTNCEFHAGRAETIlpqllkSQK 402
Cdd:COG1041 16 RALVNLAGAKEGDTVLDPFCGTGTILIEAGLLGRRVIGSDIDPKMVEGARENLEHYGYEDADVIRGDARDL------PLA 89
|
90
....*....|.
gi 269784756 403 DEKLTVAVVNP 413
Cdd:COG1041 90 DESVDAIVTDP 100
|
|
| |
