|
Name |
Accession |
Description |
Interval |
E-value |
| Tox-GHH |
pfam15636 |
GHH signature containing HNH/Endo VII superfamily nuclease toxin; A predicted toxin of the HNH ... |
3272-3349 |
1.80e-38 |
|
GHH signature containing HNH/Endo VII superfamily nuclease toxin; A predicted toxin of the HNH/Endonuclease VII fold present in bacterial polymorphic toxin systems with a characteriztic sG[HQ]H signature motif. In bacterial polymorphic toxin systems, the toxin is exported by the type 2, type 6, type 7 or TcdB/TcaC-type secretion system. The metazoan teneurin proteins possess an inactive of this domain at their C-terminus.
:
Pssm-ID: 464783 Cd Length: 78 Bit Score: 139.28 E-value: 1.80e-38
10 20 30 40 50 60 70
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 665390891 3272 KEQQRLMHHAKLTAVRKAWHREKEALRSGLTTALEWSQQETDEILKQSYANNYEGEYIHDVNLYPELAEDPYNIKFVK 3349
Cdd:pfam15636 1 EERKRLLEHAKKRAVREAWHRERQLLRNGLPGSRDWTDEEKEELLSTGSVPGYDGEYIHPVEQYPELADDPSNIRFRK 78
|
|
| NHL super family |
cl18310 |
NHL repeat unit of beta-propeller proteins; The NHL(NCL-1, HT2A and LIN-41)-repeat is found in ... |
1622-1927 |
6.67e-35 |
|
NHL repeat unit of beta-propeller proteins; The NHL(NCL-1, HT2A and LIN-41)-repeat is found in multiple tandem copies, typically as 6 instances. It is about 40 residues long and resembles the WD repeat and other beta-propeller structures. The repeats have a catalytic activity in Peptidyl-glycine alpha-amidating monooxygenase; proteolysis has shown that the Peptidyl-alpha-hydroxyglycine alpha-amidating lyase (PAL) activity is localized to the repeats. Tripartite motif-containing protein 32 interacts with the activation domain of Tat. This interaction is mediated by the NHL repeats.
The actual alignment was detected with superfamily member cd14953:
Pssm-ID: 302697 [Multi-domain] Cd Length: 323 Bit Score: 137.66 E-value: 6.67e-35
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 665390891 1622 NGVAKDAKLLTPIALATGPDGSLYVGDF--NLVRRITPDGKVYTILQL----------SATQVSYQYYLAVSPAdGHLYI 1689
Cdd:cd14953 14 GGGGTAARFNSPSGVAVDAAGNLYVADRgnHRIRKITPDGVVTTVAGTgtagfadgggAAAQFNTPSGVAVDAA-GNLYV 92
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 665390891 1690 SDPERHqilrlvRLEKVkDPSINSDPVVGSGQRcipgdeGNCGDGGpALLARLSHPKGLAIAADRTMYIADGTN--IRAV 1767
Cdd:cd14953 93 ADTGNH------RIRKI-TPDGVVSTLAGTGTA------GFSDDGG-ATAAQFNYPTGVAVDAAGNLYVADTGNhrIRKI 158
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 665390891 1768 DPKGVIHTLIGhhghhnhwSPAPCS---GTlmANQAQLQWPTGLALSPlDGSLhFIDDRL---VLRLTSDMKIRVVAGTp 1841
Cdd:cd14953 159 TPDGVVTTVAG--------TGGAGYagdGP--ATAAQFNNPTGVAVDA-AGNL-YVADRGnhrIRKITPDGVVTTVAGT- 225
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 665390891 1842 lhcsnGGQDGRVNKTGADNVLGTVLAMAFSPFGNLYIADSDSRRvnsIRVVDTAGNMRYFAGKQEGTgsqtcdcaigGGS 1921
Cdd:cd14953 226 -----GTAGFSGDGGATAAQLNNPTGVAVDAAGNLYVADSGNHR---IRKITPAGVVTTVAGGGAGF----------SGD 287
|
....*.
gi 665390891 1922 NGSATN 1927
Cdd:cd14953 288 GGPATS 293
|
|
| RhsA |
COG3209 |
Uncharacterized conserved protein RhaS, contains 28 RHS repeats [General function prediction ... |
2366-3015 |
1.17e-29 |
|
Uncharacterized conserved protein RhaS, contains 28 RHS repeats [General function prediction only];
:
Pssm-ID: 442442 [Multi-domain] Cd Length: 1103 Bit Score: 130.26 E-value: 1.17e-29
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 665390891 2366 YSVYSLVGDVRNPQQTLNREIWVNQSRVIGVEFDQFTNRETFYDARRTPILIVAYDQSGLPKSYYPTNGYPVNITYDRFN 2445
Cdd:COG3209 375 GGSTSGSTTTVGGGGTATGSGGGSSTTGVGAGTTTTSTTGGDGGPATAAGALTAGGTATGTGTGGGGTTAGTDATTTTGG 454
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 665390891 2446 RVEGWAWGPAELKYSYDRHGLLSEITSQQDGIVSFVYNDWNLVSEIGLASQRkfvlqYDDAGGLRHVVLPSGTRHSFSMQ 2525
Cdd:COG3209 455 AGASGTLTTTGGAATGATTGGGTEAGTGGGTLTSGSAGATTLGTDTTLDDTL-----GGTTTTTAGARGLVVTTGTTLTL 529
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 665390891 2526 TSIGFIRCTYTPPGSTRAYLQHYSHAGALLQTILPGDGARIVYRYNAAGQLTEVVHGDGRSEFQYNEATGMPSTVSHTER 2605
Cdd:COG3209 530 GTTTTATLSATDATGTGDTTTTGTVGTGTSTGTGGTGTVTTTGDGTGGASTTTGTTGGTATTTTVTTTTTTSTAGTTTTT 609
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 665390891 2606 ELEY-RWDFEYAAGLLAEERIDYVAKTGLSNAKFSYEYDSQLRVVALQGRIGGQSLPTQAFAYDPRTGRPSLIGQFRFSQ 2684
Cdd:COG3209 610 TSGYtRAGLTLTLGTGTASGLERATASTGSTTGGTTGTGVTTTGTTTTRATGTTGTGTGVTAGLTTLATGGTTVGGGTGT 689
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 665390891 2685 PAQNQTQLHDGTASFTRTVDGRFQTQRMALAIHRLEVFRMEFSYGVHGRISQTRTYTRNMAVNSYTNVKNYTWDCDGQLV 2764
Cdd:COG3209 690 TSTATTGATTGGTETGTTVTTLAGGTTTRLGTTTTGGGGGTTTDGTGTGGTTGTLTTTSTTTTTTAGALTYTYDALGRLT 769
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 665390891 2765 GVEAQEP-------WGFRYDDNGNLLSLTY-RGNTIPMEYNAQDRIVK-----------FGEGQYKYDARGLVAQ----- 2820
Cdd:COG3209 770 SETTPGGvtqgtytTRYTYDALGRLTSVTYpDGETVTYTYDALGRLTSvitvgsgggtdLQDRTYTYDAAGNITSitdal 849
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 665390891 2821 --NAREERFHYNTQGLLVRASKRGRfDVRYYYDHLKRLTTRKDnfGNVTQFFYTNQQRPYEVSQiyspRDGKLMSLTYDD 2898
Cdd:COG3209 850 raGTLTQTYTYDALGRLTSATDPGT-TESYTYDANGNLTSRTD--GGTTTYTYDALGRLVSVTK----PDGTTTTYTYDA 922
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 665390891 2899 VGHliyaqvyrhkyyvaTDQSGTPLMLFNQYGEGIREIMRSPFGHIVYDSNPYLYLPIDFCGGILDQVTTLVHMGdGRVY 2978
Cdd:COG3209 923 LGH--------------TDHLGSVRALTDASGQVVWRYDYDPFGNLLAETSGAAANPLRFTGQEYDAETGLYYNG-ARYY 987
|
650 660 670
....*....|....*....|....*....|....*..
gi 665390891 2979 DPLIGQWMSPDwqrvaeRIITPTRLHLYRFNGNDPIN 3015
Cdd:COG3209 988 DPALGRFLSPD------PIGLAGGLNLYAYVGNNPVN 1018
|
|
| acid_disulf_rpt |
NF033662 |
acidic double-disulfide repeat; The acidic double-disulfide repeat is an Asp-rich repeat with ... |
1199-1225 |
3.04e-09 |
|
acidic double-disulfide repeat; The acidic double-disulfide repeat is an Asp-rich repeat with four nearly invariant Cys residues in a repeat length of about 35 amino acids.
:
Pssm-ID: 411265 [Multi-domain] Cd Length: 32 Bit Score: 54.44 E-value: 3.04e-09
10 20
....*....|....*....|....*..
gi 665390891 1199 NCKDNIDNDGDGMTDCSDSECCSHPAC 1225
Cdd:NF033662 6 TCSDGIDNDGDGLTDCADPDCAGNPVC 32
|
|
| EGF_2 |
pfam07974 |
EGF-like domain; This family contains EGF domains found in a variety of extracellular proteins. |
1034-1057 |
2.39e-05 |
|
EGF-like domain; This family contains EGF domains found in a variety of extracellular proteins.
:
Pssm-ID: 400365 Cd Length: 26 Bit Score: 43.49 E-value: 2.39e-05
10 20
....*....|....*....|....*.
gi 665390891 1034 LCSGHGTCVA--GQCYCKAGWQGEDC 1057
Cdd:pfam07974 1 ICSGRGTCVNqcGKCVCDSGYQGATC 26
|
|
| C_rich_MXAN6577 super family |
cl49352 |
MXAN_6577-like cysteine-rich domain; |
1035-1146 |
3.45e-04 |
|
MXAN_6577-like cysteine-rich domain;
The actual alignment was detected with superfamily member NF041328:
Pssm-ID: 469225 [Multi-domain] Cd Length: 145 Bit Score: 43.59 E-value: 3.45e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 665390891 1035 CSGHGTCVAGQCYCKAGwqGEDCGtidqqvyqclpgcsehgtydletGQCVCERhwTGPD-CSQavCSLDCGRNGVCESG 1113
Cdd:NF041328 49 CGAGQTCVAGACGCGPG--TVACG-----------------------GACVDTA--SDPAhCGA--CGAACAPGQVCEGG 99
|
90 100 110 120
....*....|....*....|....*....|....*....|....*
gi 665390891 1114 KCR--CNSGWT--GNLC-----DQL---PCDSRCSEHGQCKNGTC 1146
Cdd:NF041328 100 ACReaCSEGLTrcGGACvdlatDPLhcgACGVACDPGESCRGGAC 144
|
|
| RHS_core super family |
cl49306 |
RHS element core protein; |
2118-2248 |
3.93e-04 |
|
RHS element core protein;
The actual alignment was detected with superfamily member NF041261:
Pssm-ID: 469161 [Multi-domain] Cd Length: 1261 Bit Score: 46.53 E-value: 3.93e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 665390891 2118 SSEIYVFNRYGQHVATKDLTSGKTRYSFlysknTSFGRLSTVTDASGnkIQFLRDYSN--VVSSIENTQDHKSEIQINGI 2195
Cdd:NF041261 535 STKQMTWSRYGQLLAFTDCSGYQTRYEY-----DRFGQMTAVHREEG--ISTYRRYDNrgQLTSVKDAQGRETRYEYNAA 607
|
90 100 110 120 130
....*....|....*....|....*....|....*....|....*....|...
gi 665390891 2196 GIMTKLSEKGRQEIELDYDSnTGLLNSRSSGGETYIYQYDEFGRVTGMILPSG 2248
Cdd:NF041261 608 GDLTAVITPDGNRSETQYDA-WGKAVSTTQGGLTRSMEYDAAGRITTLTNENG 659
|
|
| EGF_2 |
pfam07974 |
EGF-like domain; This family contains EGF domains found in a variety of extracellular proteins. |
937-960 |
7.53e-04 |
|
EGF-like domain; This family contains EGF domains found in a variety of extracellular proteins.
:
Pssm-ID: 400365 Cd Length: 26 Bit Score: 39.25 E-value: 7.53e-04
10 20
....*....|....*....|....*.
gi 665390891 937 DCSGRGSCYL--GKCDCIDGYQGVDC 960
Cdd:pfam07974 1 ICSGRGTCVNqcGKCVCDSGYQGATC 26
|
|
| EGF_2 |
pfam07974 |
EGF-like domain; This family contains EGF domains found in a variety of extracellular proteins. |
1003-1025 |
1.64e-03 |
|
EGF-like domain; This family contains EGF domains found in a variety of extracellular proteins.
:
Pssm-ID: 400365 Cd Length: 26 Bit Score: 38.10 E-value: 1.64e-03
10 20
....*....|....*....|....*
gi 665390891 1003 CSSHGRCI--EGECHCERGWKGPYC 1025
Cdd:pfam07974 2 CSGRGTCVnqCGKCVCDSGYQGATC 26
|
|
| EGF_CA |
cd00054 |
Calcium-binding EGF-like domain, present in a large number of membrane-bound and extracellular ... |
1163-1192 |
3.45e-03 |
|
Calcium-binding EGF-like domain, present in a large number of membrane-bound and extracellular (mostly animal) proteins. Many of these proteins require calcium for their biological function and calcium-binding sites have been found to be located at the N-terminus of particular EGF-like domains; calcium-binding may be crucial for numerous protein-protein interactions. Six conserved core cysteines form three disulfide bridges as in non calcium-binding EGF domains, whose structures are very similar. EGF_CA can be found in tandem repeat arrangements.
:
Pssm-ID: 238011 Cd Length: 38 Bit Score: 37.62 E-value: 3.45e-03
10 20 30
....*....|....*....|....*....|
gi 665390891 1163 ENGCSRHGQCTLENGEYRCDCIEGWAGRDC 1192
Cdd:cd00054 8 GNPCQNGGTCVNTVGSYRCSCPPGYTGRNC 37
|
|
| |
|
Name |
Accession |
Description |
Interval |
E-value |
| Tox-GHH |
pfam15636 |
GHH signature containing HNH/Endo VII superfamily nuclease toxin; A predicted toxin of the HNH ... |
3272-3349 |
1.80e-38 |
|
GHH signature containing HNH/Endo VII superfamily nuclease toxin; A predicted toxin of the HNH/Endonuclease VII fold present in bacterial polymorphic toxin systems with a characteriztic sG[HQ]H signature motif. In bacterial polymorphic toxin systems, the toxin is exported by the type 2, type 6, type 7 or TcdB/TcaC-type secretion system. The metazoan teneurin proteins possess an inactive of this domain at their C-terminus.
Pssm-ID: 464783 Cd Length: 78 Bit Score: 139.28 E-value: 1.80e-38
10 20 30 40 50 60 70
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 665390891 3272 KEQQRLMHHAKLTAVRKAWHREKEALRSGLTTALEWSQQETDEILKQSYANNYEGEYIHDVNLYPELAEDPYNIKFVK 3349
Cdd:pfam15636 1 EERKRLLEHAKKRAVREAWHRERQLLRNGLPGSRDWTDEEKEELLSTGSVPGYDGEYIHPVEQYPELADDPSNIRFRK 78
|
|
| NHL_like_1 |
cd14953 |
Uncharacterized NHL-repeat domain in bacterial proteins; This bacterial family of NHL-repeat ... |
1622-1927 |
6.67e-35 |
|
Uncharacterized NHL-repeat domain in bacterial proteins; This bacterial family of NHL-repeat domains is found in a variety of domain architectures. The NHL (NCL-1, HT2A and LIN-41) repeat is found in multiple tandem copies, typically as 6 instances. It is about 40 residues long and resembles the WD repeat and other beta-propeller structures.
Pssm-ID: 271323 [Multi-domain] Cd Length: 323 Bit Score: 137.66 E-value: 6.67e-35
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 665390891 1622 NGVAKDAKLLTPIALATGPDGSLYVGDF--NLVRRITPDGKVYTILQL----------SATQVSYQYYLAVSPAdGHLYI 1689
Cdd:cd14953 14 GGGGTAARFNSPSGVAVDAAGNLYVADRgnHRIRKITPDGVVTTVAGTgtagfadgggAAAQFNTPSGVAVDAA-GNLYV 92
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 665390891 1690 SDPERHqilrlvRLEKVkDPSINSDPVVGSGQRcipgdeGNCGDGGpALLARLSHPKGLAIAADRTMYIADGTN--IRAV 1767
Cdd:cd14953 93 ADTGNH------RIRKI-TPDGVVSTLAGTGTA------GFSDDGG-ATAAQFNYPTGVAVDAAGNLYVADTGNhrIRKI 158
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 665390891 1768 DPKGVIHTLIGhhghhnhwSPAPCS---GTlmANQAQLQWPTGLALSPlDGSLhFIDDRL---VLRLTSDMKIRVVAGTp 1841
Cdd:cd14953 159 TPDGVVTTVAG--------TGGAGYagdGP--ATAAQFNNPTGVAVDA-AGNL-YVADRGnhrIRKITPDGVVTTVAGT- 225
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 665390891 1842 lhcsnGGQDGRVNKTGADNVLGTVLAMAFSPFGNLYIADSDSRRvnsIRVVDTAGNMRYFAGKQEGTgsqtcdcaigGGS 1921
Cdd:cd14953 226 -----GTAGFSGDGGATAAQLNNPTGVAVDAAGNLYVADSGNHR---IRKITPAGVVTTVAGGGAGF----------SGD 287
|
....*.
gi 665390891 1922 NGSATN 1927
Cdd:cd14953 288 GGPATS 293
|
|
| RhsA |
COG3209 |
Uncharacterized conserved protein RhaS, contains 28 RHS repeats [General function prediction ... |
2366-3015 |
1.17e-29 |
|
Uncharacterized conserved protein RhaS, contains 28 RHS repeats [General function prediction only];
Pssm-ID: 442442 [Multi-domain] Cd Length: 1103 Bit Score: 130.26 E-value: 1.17e-29
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 665390891 2366 YSVYSLVGDVRNPQQTLNREIWVNQSRVIGVEFDQFTNRETFYDARRTPILIVAYDQSGLPKSYYPTNGYPVNITYDRFN 2445
Cdd:COG3209 375 GGSTSGSTTTVGGGGTATGSGGGSSTTGVGAGTTTTSTTGGDGGPATAAGALTAGGTATGTGTGGGGTTAGTDATTTTGG 454
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 665390891 2446 RVEGWAWGPAELKYSYDRHGLLSEITSQQDGIVSFVYNDWNLVSEIGLASQRkfvlqYDDAGGLRHVVLPSGTRHSFSMQ 2525
Cdd:COG3209 455 AGASGTLTTTGGAATGATTGGGTEAGTGGGTLTSGSAGATTLGTDTTLDDTL-----GGTTTTTAGARGLVVTTGTTLTL 529
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 665390891 2526 TSIGFIRCTYTPPGSTRAYLQHYSHAGALLQTILPGDGARIVYRYNAAGQLTEVVHGDGRSEFQYNEATGMPSTVSHTER 2605
Cdd:COG3209 530 GTTTTATLSATDATGTGDTTTTGTVGTGTSTGTGGTGTVTTTGDGTGGASTTTGTTGGTATTTTVTTTTTTSTAGTTTTT 609
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 665390891 2606 ELEY-RWDFEYAAGLLAEERIDYVAKTGLSNAKFSYEYDSQLRVVALQGRIGGQSLPTQAFAYDPRTGRPSLIGQFRFSQ 2684
Cdd:COG3209 610 TSGYtRAGLTLTLGTGTASGLERATASTGSTTGGTTGTGVTTTGTTTTRATGTTGTGTGVTAGLTTLATGGTTVGGGTGT 689
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 665390891 2685 PAQNQTQLHDGTASFTRTVDGRFQTQRMALAIHRLEVFRMEFSYGVHGRISQTRTYTRNMAVNSYTNVKNYTWDCDGQLV 2764
Cdd:COG3209 690 TSTATTGATTGGTETGTTVTTLAGGTTTRLGTTTTGGGGGTTTDGTGTGGTTGTLTTTSTTTTTTAGALTYTYDALGRLT 769
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 665390891 2765 GVEAQEP-------WGFRYDDNGNLLSLTY-RGNTIPMEYNAQDRIVK-----------FGEGQYKYDARGLVAQ----- 2820
Cdd:COG3209 770 SETTPGGvtqgtytTRYTYDALGRLTSVTYpDGETVTYTYDALGRLTSvitvgsgggtdLQDRTYTYDAAGNITSitdal 849
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 665390891 2821 --NAREERFHYNTQGLLVRASKRGRfDVRYYYDHLKRLTTRKDnfGNVTQFFYTNQQRPYEVSQiyspRDGKLMSLTYDD 2898
Cdd:COG3209 850 raGTLTQTYTYDALGRLTSATDPGT-TESYTYDANGNLTSRTD--GGTTTYTYDALGRLVSVTK----PDGTTTTYTYDA 922
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 665390891 2899 VGHliyaqvyrhkyyvaTDQSGTPLMLFNQYGEGIREIMRSPFGHIVYDSNPYLYLPIDFCGGILDQVTTLVHMGdGRVY 2978
Cdd:COG3209 923 LGH--------------TDHLGSVRALTDASGQVVWRYDYDPFGNLLAETSGAAANPLRFTGQEYDAETGLYYNG-ARYY 987
|
650 660 670
....*....|....*....|....*....|....*..
gi 665390891 2979 DPLIGQWMSPDwqrvaeRIITPTRLHLYRFNGNDPIN 3015
Cdd:COG3209 988 DPALGRFLSPD------PIGLAGGLNLYAYVGNNPVN 1018
|
|
| RHS_core |
NF041261 |
RHS element core protein; |
2450-2902 |
5.06e-14 |
|
RHS element core protein;
Pssm-ID: 469161 [Multi-domain] Cd Length: 1261 Bit Score: 78.89 E-value: 5.06e-14
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 665390891 2450 WAWGPA-ELKYSYDRHGllseitSQqdgIVSFVYNDWNLVSEIG--LASQRKFVLQYDDAGGLRHVVLPSGTRHSFSMQT 2526
Cdd:NF041261 322 YTYTEAgELLAVYDRSN------TQ---VRAFTYDAQHPGRMVAhrYAGRPEMCYRYDDTGRVTEQLNPAGLSYRYQYEQ 392
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 665390891 2527 SigfiRCTYTPPGSTRAYLqhYSHAGALLQTILP---GDGARIVYRYNAAGQLTEVVHGDGR-SEFQYNEATGMPSTVSH 2602
Cdd:NF041261 393 D----RITITDSLNRREVL--HTEGEGGLKRVVKkehADGSVTRSGYDAAGRLTAQTDAAGRrTEYSLNVVSGDITDITT 466
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 665390891 2603 TE-RELEYRWDfeyaagllaeERIDYVAKTGLSNAKFSYEYDSQLRVVALQGRIGgqslPTQAFAYD-PRTGRPSLIG-- 2678
Cdd:NF041261 467 PDgRETKFYYN----------DGNQLTSVTSPDGLESRREYDEPGRLVSETSRSG----ETTRYRYDdPHSELPATTTda 532
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 665390891 2679 -----QFRFSQPAQnQTQLHDGTASFTRTVDGRFQTQrmaLAIHRLEVFRMEFSYGVHGRISQTRtytrnmavNSYTNVK 2753
Cdd:NF041261 533 tgstkQMTWSRYGQ-LLAFTDCSGYQTRYEYDRFGQM---TAVHREEGISTYRRYDNRGQLTSVK--------DAQGRET 600
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 665390891 2754 NYTWDCDGQLVGVEAqePWGFR----YDDNGNLLSLTYRGNTIPMEYNAQDRIVKF-----GEGQYKYDARGLVAQ---- 2820
Cdd:NF041261 601 RYEYNAAGDLTAVIT--PDGNRsetqYDAWGKAVSTTQGGLTRSMEYDAAGRITTLtnengSHSTFLYDALDRLVQqrgf 678
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 665390891 2821 NAREERFHYNTQGLLVRASKRGrFDVRYYYDHLKRLTTRKDNFGNVTQFFYTNQQRPYEVSQIyspRDGKLMSL--TYDD 2898
Cdd:NF041261 679 DGRTQRYHYDLTGKLTQSEDEG-LVTLWHYDESDRITHRTVNGEPAEQWQYDEHGWLTDISHL---SEGHRVAVhyGYDD 754
|
....
gi 665390891 2899 VGHL 2902
Cdd:NF041261 755 KGRL 758
|
|
| Vgb |
COG4257 |
Streptogramin lyase [Defense mechanisms]; |
1627-1902 |
1.02e-11 |
|
Streptogramin lyase [Defense mechanisms];
Pssm-ID: 443399 [Multi-domain] Cd Length: 270 Bit Score: 68.12 E-value: 1.02e-11
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 665390891 1627 DAKLLTPIALATGPDGSLYVGDF--NLVRRITPDGKVYTILQLSATQvSYQYYLAVSPaDGHLYISDPERHQILRLvrle 1704
Cdd:COG4257 55 LGGGSGPHGIAVDPDGNLWFTDNgnNRIGRIDPKTGEITTFALPGGG-SNPHGIAFDP-DGNLWFTDQGGNRIGRL---- 128
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 665390891 1705 kvkdpsinsDPVVGSgqrcIPGDEGNCGDGGPAllarlshpkGLAIAADRTMYIAD-GTN-IRAVDPK-GVIHTLighhg 1781
Cdd:COG4257 129 ---------DPATGE----VTEFPLPTGGAGPY---------GIAVDPDGNLWVTDfGANaIGRIDPDtGTLTEY----- 181
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 665390891 1782 hhnhwspapcsgtlmANQAQLQWPTGLALSPlDGSLHFIDdrlvlrltsdmkirvvagtplhcSNGGQDGRVN-KTGADN 1860
Cdd:COG4257 182 ---------------ALPTPGAGPRGLAVDP-DGNLWVAD-----------------------TGSGRIGRFDpKTGTVT 222
|
250 260 270 280
....*....|....*....|....*....|....*....|....*...
gi 665390891 1861 VLGTVL------AMAFSPFGNLYIADSDSrrvNSIRVVDTAGNMRYFA 1902
Cdd:COG4257 223 EYPLPGggarpyGVAVDGDGRVWFAESGA---NRIVRFDPDTELTEYV 267
|
|
| RHS_core |
NF041261 |
RHS element core protein; |
2223-2860 |
3.71e-11 |
|
RHS element core protein;
Pssm-ID: 469161 [Multi-domain] Cd Length: 1261 Bit Score: 69.65 E-value: 3.71e-11
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 665390891 2223 RSSGGETYIYQYDEFGRVTGMILPSGeiVRITSQLADSQgLTVyvhasVESLFSRERIAGEANellvlGGVRSTFLKRgq 2302
Cdd:NF041261 358 RYAGRPEMCYRYDDTGRVTEQLNPAG--LSYRYQYEQDR-ITI-----TDSLNRREVLHTEGE-----GGLKRVVKKE-- 422
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 665390891 2303 aHADAELKANntlvihgdngvvvEASAVARhplLEAalpveaemlamwshQSVTMGEGLTNSMYSVYSLVGDVRNPQQTL 2382
Cdd:NF041261 423 -HADGSVTRS-------------GYDAAGR---LTA--------------QTDAAGRRTEYSLNVVSGDITDITTPDGRE 471
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 665390891 2383 NREIWVNQSRVIGV----------EFDQfTNRETFYDARRTPILIVAYD--QSGLPKSYYPTNGYPVNITYDRFNRVEGW 2450
Cdd:NF041261 472 TKFYYNDGNQLTSVtspdglesrrEYDE-PGRLVSETSRSGETTRYRYDdpHSELPATTTDATGSTKQMTWSRYGQLLAF 550
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 665390891 2451 A-WGPAELKYSYDRHGLLSEItSQQDGIVSF-VYNDWNLVSEIGLASQRKFVLQYDDAGGLRHVVLPSGTRhSFSMQTSI 2528
Cdd:NF041261 551 TdCSGYQTRYEYDRFGQMTAV-HREEGISTYrRYDNRGQLTSVKDAQGRETRYEYNAAGDLTAVITPDGNR-SETQYDAW 628
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 665390891 2529 GFIRCTyTPPGSTRAylQHYSHAGALLqTILPGDGARIVYRYNAAGQLTEVVHGDGRSEFQYNEATGmpsTVSHTERE-L 2607
Cdd:NF041261 629 GKAVST-TQGGLTRS--MEYDAAGRIT-TLTNENGSHSTFLYDALDRLVQQRGFDGRTQRYHYDLTG---KLTQSEDEgL 701
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 665390891 2608 EYRWDFEyaagllAEERIDYVAKTGLSNAKFSYE---------YDSQLRVVAL------QGRIGGQSLPTQafayDPRTG 2672
Cdd:NF041261 702 VTLWHYD------ESDRITHRTVNGEPAEQWQYDehgwltdisHLSEGHRVAVhygyddKGRLTGERQTVE----NPETG 771
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 665390891 2673 RpsLIGQFR----FSQPAQNQTQLHDGTASFTRTVDGRFQTQRMALA-----------IHRlEVFRMEFSYGVHGRISQT 2737
Cdd:NF041261 772 E--LLWQHEtghaYNEQGLANRVTPDSLPPVEWLTYGSGYLAGMKLGgtplveytrdrLHR-ETVRSFGGAGSNAAYELT 848
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 665390891 2738 RTYT-----RNMAVNSYTNVKNYTWDCDGQLVGVEA-QEPWGFRYDDNGNLLS-------LTYR--------GNTIP--- 2793
Cdd:NF041261 849 TAYTpagqlQSQHLNSLVYDRDYTWNDNGDLVRISGpRQTREYGYSATGRLTGvhttaanLDIRipyatdpaGNRLPdpe 928
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 665390891 2794 ------MEYNAQDRIVKFGEGQYKYDARGLVAQ-------------NAREERFHYNTQGLLVRASK----RGRFDVRYYY 2850
Cdd:NF041261 929 lhpdstLTAWPDNRIAEDAHYVYRYDEYGRLTEktdripegvirtdDERTHHYHYDSQHRLVFYTRiqhgEPLVESRYLY 1008
|
730
....*....|
gi 665390891 2851 DHLKRLTTRK 2860
Cdd:NF041261 1009 DPLGRRMAKR 1018
|
|
| acid_disulf_rpt |
NF033662 |
acidic double-disulfide repeat; The acidic double-disulfide repeat is an Asp-rich repeat with ... |
1199-1225 |
3.04e-09 |
|
acidic double-disulfide repeat; The acidic double-disulfide repeat is an Asp-rich repeat with four nearly invariant Cys residues in a repeat length of about 35 amino acids.
Pssm-ID: 411265 [Multi-domain] Cd Length: 32 Bit Score: 54.44 E-value: 3.04e-09
10 20
....*....|....*....|....*..
gi 665390891 1199 NCKDNIDNDGDGMTDCSDSECCSHPAC 1225
Cdd:NF033662 6 TCSDGIDNDGDGLTDCADPDCAGNPVC 32
|
|
| Rhs_assc_core |
TIGR03696 |
RHS repeat-associated core domain; This model represents a conserved unique core sequence ... |
2939-3015 |
3.57e-08 |
|
RHS repeat-associated core domain; This model represents a conserved unique core sequence shared by large numbers of proteins. It is occasional in the Archaea Methanosarcina barkeri) but common in bacteria and eukaryotes. Most fall into two large classes. One class consists of long proteins in which two classes of repeats are abundant: an FG-GAP repeat (pfam01839) class, and an RHS repeat (pfam05593) or YD repeat (TIGR01643). This class includes secreted bacterial insecticidal toxins and intercellular signalling proteins such as the teneurins in animals. The other class consists of uncharacterized proteins shorter than 400 amino acids, where this core domain of about 75 amino acids tends to occur in the N-terminal half. Over twenty such proteins are found in Pseudomonas putida alone; little sequence similarity or repeat structure is found among these proteins outside the region modeled by this domain.
Pssm-ID: 274730 [Multi-domain] Cd Length: 77 Bit Score: 52.89 E-value: 3.57e-08
10 20 30 40 50 60 70
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 665390891 2939 SPFGHIVYDSNPyLYLPIDFCGGILDQVTTLVHMGdGRVYDPLIGQWMSPDwqrvaeRIITPTRLHLYRFNGNDPIN 3015
Cdd:TIGR03696 2 DPYGEVLSESGA-APNPLRFTGQYYDAETGLYYNG-ARYYDPELGRFLSPD------PIGLGGGLNLYAYVGNNPVN 70
|
|
| EGF_2 |
pfam07974 |
EGF-like domain; This family contains EGF domains found in a variety of extracellular proteins. |
1034-1057 |
2.39e-05 |
|
EGF-like domain; This family contains EGF domains found in a variety of extracellular proteins.
Pssm-ID: 400365 Cd Length: 26 Bit Score: 43.49 E-value: 2.39e-05
10 20
....*....|....*....|....*.
gi 665390891 1034 LCSGHGTCVA--GQCYCKAGWQGEDC 1057
Cdd:pfam07974 1 ICSGRGTCVNqcGKCVCDSGYQGATC 26
|
|
| C_rich_MXAN6577 |
NF041328 |
MXAN_6577-like cysteine-rich domain; |
1035-1146 |
3.45e-04 |
|
MXAN_6577-like cysteine-rich domain;
Pssm-ID: 469225 [Multi-domain] Cd Length: 145 Bit Score: 43.59 E-value: 3.45e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 665390891 1035 CSGHGTCVAGQCYCKAGwqGEDCGtidqqvyqclpgcsehgtydletGQCVCERhwTGPD-CSQavCSLDCGRNGVCESG 1113
Cdd:NF041328 49 CGAGQTCVAGACGCGPG--TVACG-----------------------GACVDTA--SDPAhCGA--CGAACAPGQVCEGG 99
|
90 100 110 120
....*....|....*....|....*....|....*....|....*
gi 665390891 1114 KCR--CNSGWT--GNLC-----DQL---PCDSRCSEHGQCKNGTC 1146
Cdd:NF041328 100 ACReaCSEGLTrcGGACvdlatDPLhcgACGVACDPGESCRGGAC 144
|
|
| RHS_core |
NF041261 |
RHS element core protein; |
2118-2248 |
3.93e-04 |
|
RHS element core protein;
Pssm-ID: 469161 [Multi-domain] Cd Length: 1261 Bit Score: 46.53 E-value: 3.93e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 665390891 2118 SSEIYVFNRYGQHVATKDLTSGKTRYSFlysknTSFGRLSTVTDASGnkIQFLRDYSN--VVSSIENTQDHKSEIQINGI 2195
Cdd:NF041261 535 STKQMTWSRYGQLLAFTDCSGYQTRYEY-----DRFGQMTAVHREEG--ISTYRRYDNrgQLTSVKDAQGRETRYEYNAA 607
|
90 100 110 120 130
....*....|....*....|....*....|....*....|....*....|...
gi 665390891 2196 GIMTKLSEKGRQEIELDYDSnTGLLNSRSSGGETYIYQYDEFGRVTGMILPSG 2248
Cdd:NF041261 608 GDLTAVITPDGNRSETQYDA-WGKAVSTTQGGLTRSMEYDAAGRITTLTNENG 659
|
|
| PLN02919 |
PLN02919 |
haloacid dehalogenase-like hydrolase family protein |
1669-1770 |
4.51e-04 |
|
haloacid dehalogenase-like hydrolase family protein
Pssm-ID: 215497 [Multi-domain] Cd Length: 1057 Bit Score: 46.38 E-value: 4.51e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 665390891 1669 ATQVSYQYYLAV-SPADGHLYISDPERHQIlrlvrleKVKDPSINS-DPVVGSGQRCIpgdegncgDGGPALLARLSHPK 1746
Cdd:PLN02919 798 GSEVLLQHPLGVlCAKDGQIYVADSYNHKI-------KKLDPATKRvTTLAGTGKAGF--------KDGKALKAQLSEPA 862
|
90 100
....*....|....*....|....*.
gi 665390891 1747 GLAIAADRTMYIADGTN--IRAVDPK 1770
Cdd:PLN02919 863 GLALGENGRLFVADTNNslIRYLDLN 888
|
|
| DSL |
pfam01414 |
Delta serrate ligand; This family has been redefined to correspond to the EGF-like domain ... |
1117-1160 |
6.81e-04 |
|
Delta serrate ligand; This family has been redefined to correspond to the EGF-like domain defined by structure.
Pssm-ID: 460202 Cd Length: 46 Bit Score: 39.91 E-value: 6.81e-04
10 20 30 40 50
....*....|....*....|....*....|....*....|....*....|..
gi 665390891 1117 CNSGWTGNLCDQLpCDSR--------CSEHGQCkngtcVCSQGWNGRHCTLP 1160
Cdd:pfam01414 1 CDENYYGSTCSKF-CRPRddkfghytCDANGNK-----VCLPGWTGPYCDKP 46
|
|
| EGF_2 |
pfam07974 |
EGF-like domain; This family contains EGF domains found in a variety of extracellular proteins. |
937-960 |
7.53e-04 |
|
EGF-like domain; This family contains EGF domains found in a variety of extracellular proteins.
Pssm-ID: 400365 Cd Length: 26 Bit Score: 39.25 E-value: 7.53e-04
10 20
....*....|....*....|....*.
gi 665390891 937 DCSGRGSCYL--GKCDCIDGYQGVDC 960
Cdd:pfam07974 1 ICSGRGTCVNqcGKCVCDSGYQGATC 26
|
|
| EGF_2 |
pfam07974 |
EGF-like domain; This family contains EGF domains found in a variety of extracellular proteins. |
1003-1025 |
1.64e-03 |
|
EGF-like domain; This family contains EGF domains found in a variety of extracellular proteins.
Pssm-ID: 400365 Cd Length: 26 Bit Score: 38.10 E-value: 1.64e-03
10 20
....*....|....*....|....*
gi 665390891 1003 CSSHGRCI--EGECHCERGWKGPYC 1025
Cdd:pfam07974 2 CSGRGTCVnqCGKCVCDSGYQGATC 26
|
|
| RHS_repeat |
pfam05593 |
RHS Repeat; RHS proteins contain extended repeat regions. These repeats often appear to be ... |
2213-2249 |
2.38e-03 |
|
RHS Repeat; RHS proteins contain extended repeat regions. These repeats often appear to be involved in ligand binding. Note that this model may not find all the repeats in a protein and that it covers two RHS repeats. The 3D structure of an RHS-repeat-containing protein (the B and C components of an ABC toxin complex) has been determined. The RHS repeats form an extended strip of beta-sheet that spirals around to form a hollow shell, encapsulating the variable C-terminal domain.
Pssm-ID: 461685 [Multi-domain] Cd Length: 37 Bit Score: 37.96 E-value: 2.38e-03
10 20 30
....*....|....*....|....*....|....*..
gi 665390891 2213 YDSNTGLLNSRSSGGETYIYQYDEFGRVTGMILPSGE 2249
Cdd:pfam05593 1 YDAAGRLTSVTDPDGRVTTYTYDAAGRLTAVTDPDGT 37
|
|
| EGF_CA |
cd00054 |
Calcium-binding EGF-like domain, present in a large number of membrane-bound and extracellular ... |
1163-1192 |
3.45e-03 |
|
Calcium-binding EGF-like domain, present in a large number of membrane-bound and extracellular (mostly animal) proteins. Many of these proteins require calcium for their biological function and calcium-binding sites have been found to be located at the N-terminus of particular EGF-like domains; calcium-binding may be crucial for numerous protein-protein interactions. Six conserved core cysteines form three disulfide bridges as in non calcium-binding EGF domains, whose structures are very similar. EGF_CA can be found in tandem repeat arrangements.
Pssm-ID: 238011 Cd Length: 38 Bit Score: 37.62 E-value: 3.45e-03
10 20 30
....*....|....*....|....*....|
gi 665390891 1163 ENGCSRHGQCTLENGEYRCDCIEGWAGRDC 1192
Cdd:cd00054 8 GNPCQNGGTCVNTVGSYRCSCPPGYTGRNC 37
|
|
| EGF_CA |
cd00054 |
Calcium-binding EGF-like domain, present in a large number of membrane-bound and extracellular ... |
1131-1158 |
7.00e-03 |
|
Calcium-binding EGF-like domain, present in a large number of membrane-bound and extracellular (mostly animal) proteins. Many of these proteins require calcium for their biological function and calcium-binding sites have been found to be located at the N-terminus of particular EGF-like domains; calcium-binding may be crucial for numerous protein-protein interactions. Six conserved core cysteines form three disulfide bridges as in non calcium-binding EGF domains, whose structures are very similar. EGF_CA can be found in tandem repeat arrangements.
Pssm-ID: 238011 Cd Length: 38 Bit Score: 36.85 E-value: 7.00e-03
10 20 30
....*....|....*....|....*....|....
gi 665390891 1131 CDSR--CSEHGQCKNG----TCVCSQGWNGRHCT 1158
Cdd:cd00054 5 CASGnpCQNGGTCVNTvgsyRCSCPPGYTGRNCE 38
|
|
| |
|
Name |
Accession |
Description |
Interval |
E-value |
| Tox-GHH |
pfam15636 |
GHH signature containing HNH/Endo VII superfamily nuclease toxin; A predicted toxin of the HNH ... |
3272-3349 |
1.80e-38 |
|
GHH signature containing HNH/Endo VII superfamily nuclease toxin; A predicted toxin of the HNH/Endonuclease VII fold present in bacterial polymorphic toxin systems with a characteriztic sG[HQ]H signature motif. In bacterial polymorphic toxin systems, the toxin is exported by the type 2, type 6, type 7 or TcdB/TcaC-type secretion system. The metazoan teneurin proteins possess an inactive of this domain at their C-terminus.
Pssm-ID: 464783 Cd Length: 78 Bit Score: 139.28 E-value: 1.80e-38
10 20 30 40 50 60 70
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 665390891 3272 KEQQRLMHHAKLTAVRKAWHREKEALRSGLTTALEWSQQETDEILKQSYANNYEGEYIHDVNLYPELAEDPYNIKFVK 3349
Cdd:pfam15636 1 EERKRLLEHAKKRAVREAWHRERQLLRNGLPGSRDWTDEEKEELLSTGSVPGYDGEYIHPVEQYPELADDPSNIRFRK 78
|
|
| NHL_like_1 |
cd14953 |
Uncharacterized NHL-repeat domain in bacterial proteins; This bacterial family of NHL-repeat ... |
1622-1927 |
6.67e-35 |
|
Uncharacterized NHL-repeat domain in bacterial proteins; This bacterial family of NHL-repeat domains is found in a variety of domain architectures. The NHL (NCL-1, HT2A and LIN-41) repeat is found in multiple tandem copies, typically as 6 instances. It is about 40 residues long and resembles the WD repeat and other beta-propeller structures.
Pssm-ID: 271323 [Multi-domain] Cd Length: 323 Bit Score: 137.66 E-value: 6.67e-35
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 665390891 1622 NGVAKDAKLLTPIALATGPDGSLYVGDF--NLVRRITPDGKVYTILQL----------SATQVSYQYYLAVSPAdGHLYI 1689
Cdd:cd14953 14 GGGGTAARFNSPSGVAVDAAGNLYVADRgnHRIRKITPDGVVTTVAGTgtagfadgggAAAQFNTPSGVAVDAA-GNLYV 92
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 665390891 1690 SDPERHqilrlvRLEKVkDPSINSDPVVGSGQRcipgdeGNCGDGGpALLARLSHPKGLAIAADRTMYIADGTN--IRAV 1767
Cdd:cd14953 93 ADTGNH------RIRKI-TPDGVVSTLAGTGTA------GFSDDGG-ATAAQFNYPTGVAVDAAGNLYVADTGNhrIRKI 158
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 665390891 1768 DPKGVIHTLIGhhghhnhwSPAPCS---GTlmANQAQLQWPTGLALSPlDGSLhFIDDRL---VLRLTSDMKIRVVAGTp 1841
Cdd:cd14953 159 TPDGVVTTVAG--------TGGAGYagdGP--ATAAQFNNPTGVAVDA-AGNL-YVADRGnhrIRKITPDGVVTTVAGT- 225
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 665390891 1842 lhcsnGGQDGRVNKTGADNVLGTVLAMAFSPFGNLYIADSDSRRvnsIRVVDTAGNMRYFAGKQEGTgsqtcdcaigGGS 1921
Cdd:cd14953 226 -----GTAGFSGDGGATAAQLNNPTGVAVDAAGNLYVADSGNHR---IRKITPAGVVTTVAGGGAGF----------SGD 287
|
....*.
gi 665390891 1922 NGSATN 1927
Cdd:cd14953 288 GGPATS 293
|
|
| RhsA |
COG3209 |
Uncharacterized conserved protein RhaS, contains 28 RHS repeats [General function prediction ... |
2366-3015 |
1.17e-29 |
|
Uncharacterized conserved protein RhaS, contains 28 RHS repeats [General function prediction only];
Pssm-ID: 442442 [Multi-domain] Cd Length: 1103 Bit Score: 130.26 E-value: 1.17e-29
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 665390891 2366 YSVYSLVGDVRNPQQTLNREIWVNQSRVIGVEFDQFTNRETFYDARRTPILIVAYDQSGLPKSYYPTNGYPVNITYDRFN 2445
Cdd:COG3209 375 GGSTSGSTTTVGGGGTATGSGGGSSTTGVGAGTTTTSTTGGDGGPATAAGALTAGGTATGTGTGGGGTTAGTDATTTTGG 454
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 665390891 2446 RVEGWAWGPAELKYSYDRHGLLSEITSQQDGIVSFVYNDWNLVSEIGLASQRkfvlqYDDAGGLRHVVLPSGTRHSFSMQ 2525
Cdd:COG3209 455 AGASGTLTTTGGAATGATTGGGTEAGTGGGTLTSGSAGATTLGTDTTLDDTL-----GGTTTTTAGARGLVVTTGTTLTL 529
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 665390891 2526 TSIGFIRCTYTPPGSTRAYLQHYSHAGALLQTILPGDGARIVYRYNAAGQLTEVVHGDGRSEFQYNEATGMPSTVSHTER 2605
Cdd:COG3209 530 GTTTTATLSATDATGTGDTTTTGTVGTGTSTGTGGTGTVTTTGDGTGGASTTTGTTGGTATTTTVTTTTTTSTAGTTTTT 609
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 665390891 2606 ELEY-RWDFEYAAGLLAEERIDYVAKTGLSNAKFSYEYDSQLRVVALQGRIGGQSLPTQAFAYDPRTGRPSLIGQFRFSQ 2684
Cdd:COG3209 610 TSGYtRAGLTLTLGTGTASGLERATASTGSTTGGTTGTGVTTTGTTTTRATGTTGTGTGVTAGLTTLATGGTTVGGGTGT 689
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 665390891 2685 PAQNQTQLHDGTASFTRTVDGRFQTQRMALAIHRLEVFRMEFSYGVHGRISQTRTYTRNMAVNSYTNVKNYTWDCDGQLV 2764
Cdd:COG3209 690 TSTATTGATTGGTETGTTVTTLAGGTTTRLGTTTTGGGGGTTTDGTGTGGTTGTLTTTSTTTTTTAGALTYTYDALGRLT 769
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 665390891 2765 GVEAQEP-------WGFRYDDNGNLLSLTY-RGNTIPMEYNAQDRIVK-----------FGEGQYKYDARGLVAQ----- 2820
Cdd:COG3209 770 SETTPGGvtqgtytTRYTYDALGRLTSVTYpDGETVTYTYDALGRLTSvitvgsgggtdLQDRTYTYDAAGNITSitdal 849
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 665390891 2821 --NAREERFHYNTQGLLVRASKRGRfDVRYYYDHLKRLTTRKDnfGNVTQFFYTNQQRPYEVSQiyspRDGKLMSLTYDD 2898
Cdd:COG3209 850 raGTLTQTYTYDALGRLTSATDPGT-TESYTYDANGNLTSRTD--GGTTTYTYDALGRLVSVTK----PDGTTTTYTYDA 922
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 665390891 2899 VGHliyaqvyrhkyyvaTDQSGTPLMLFNQYGEGIREIMRSPFGHIVYDSNPYLYLPIDFCGGILDQVTTLVHMGdGRVY 2978
Cdd:COG3209 923 LGH--------------TDHLGSVRALTDASGQVVWRYDYDPFGNLLAETSGAAANPLRFTGQEYDAETGLYYNG-ARYY 987
|
650 660 670
....*....|....*....|....*....|....*..
gi 665390891 2979 DPLIGQWMSPDwqrvaeRIITPTRLHLYRFNGNDPIN 3015
Cdd:COG3209 988 DPALGRFLSPD------PIGLAGGLNLYAYVGNNPVN 1018
|
|
| NHL_like_1 |
cd14953 |
Uncharacterized NHL-repeat domain in bacterial proteins; This bacterial family of NHL-repeat ... |
1620-1889 |
8.67e-27 |
|
Uncharacterized NHL-repeat domain in bacterial proteins; This bacterial family of NHL-repeat domains is found in a variety of domain architectures. The NHL (NCL-1, HT2A and LIN-41) repeat is found in multiple tandem copies, typically as 6 instances. It is about 40 residues long and resembles the WD repeat and other beta-propeller structures.
Pssm-ID: 271323 [Multi-domain] Cd Length: 323 Bit Score: 114.16 E-value: 8.67e-27
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 665390891 1620 YCNGVAKDAKLLTPIALATGPDGSLYVGDF--NLVRRITPDGKVYTIL-----------QLSATQVSYQYYLAVSPAdGH 1686
Cdd:cd14953 66 FADGGGAAAQFNTPSGVAVDAAGNLYVADTgnHRIRKITPDGVVSTLAgtgtagfsddgGATAAQFNYPTGVAVDAA-GN 144
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 665390891 1687 LYISDPERHQILRlvrlekvkdpsINSDPVV----GSGqrcipgdEGNCGDGGPALLARLSHPKGLAIAADRTMYIADGT 1762
Cdd:cd14953 145 LYVADTGNHRIRK-----------ITPDGVVttvaGTG-------GAGYAGDGPATAAQFNNPTGVAVDAAGNLYVADRG 206
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 665390891 1763 N--IRAVDPKGVIHTLIGHHGhhnhwspAPCSGTLMANQAQLQWPTGLALSPlDGSLhFIDDRL---VLRLTSDMKIRVV 1837
Cdd:cd14953 207 NhrIRKITPDGVVTTVAGTGT-------AGFSGDGGATAAQLNNPTGVAVDA-AGNL-YVADSGnhrIRKITPAGVVTTV 277
|
250 260 270 280 290
....*....|....*....|....*....|....*....|....*....|..
gi 665390891 1838 AGTPlhCSNGGQDGRVNKTGADNVLGtvlaMAFSPFGNLYIADSDSRRVNSI 1889
Cdd:cd14953 278 AGGG--AGFSGDGGPATSAQFNNPTG----VAVDAAGNLYVADTGNNRIRKI 323
|
|
| NHL |
cd05819 |
NHL repeat unit of beta-propeller proteins; The NHL(NCL-1, HT2A and LIN-41)-repeat is found in ... |
1627-1886 |
4.17e-19 |
|
NHL repeat unit of beta-propeller proteins; The NHL(NCL-1, HT2A and LIN-41)-repeat is found in multiple tandem copies, typically as 6 instances. It is about 40 residues long and resembles the WD repeat and other beta-propeller structures. The repeats have a catalytic activity in Peptidyl-glycine alpha-amidating monooxygenase; proteolysis has shown that the Peptidyl-alpha-hydroxyglycine alpha-amidating lyase (PAL) activity is localized to the repeats. Tripartite motif-containing protein 32 interacts with the activation domain of Tat. This interaction is mediated by the NHL repeats.
Pssm-ID: 271320 [Multi-domain] Cd Length: 269 Bit Score: 90.07 E-value: 4.17e-19
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 665390891 1627 DAKLLTPIALATGPDGSLYVGDF--NLVRRITPDGKVYTILQLSATQVSYQYY---LAVSPaDGHLYISDPERHQILRLv 1701
Cdd:cd05819 51 DGQFNEPAGVAVDSDGNLYVADTgnHRIQKFDPDGNFLASFGGSGDGDGEFNGprgIAVDS-SGNIYVADTGNHRIQKF- 128
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 665390891 1702 rlekvkDPSinsdpvvGSGQRCIPGDEGNCGDggpallarLSHPKGLAIAADRTMYIADGTN--IRAVDPKGVIHTLIGH 1779
Cdd:cd05819 129 ------DPD-------GEFLTTFGSGGSGPGQ--------FNGPTGVAVDSDGNIYVADTGNhrIQVFDPDGNFLTTFGS 187
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 665390891 1780 HGHHNhwspapcsgtlmanqAQLQWPTGLALSPlDGSLHFID--DRLVLRLTSDMKIRVVAGTPLhcsnggqdgrvnktG 1857
Cdd:cd05819 188 TGTGP---------------GQFNYPTGIAVDS-DGNIYVADsgNNRVQVFDPDGAGFGGNGNFL--------------G 237
|
250 260
....*....|....*....|....*....
gi 665390891 1858 ADNVLGTVLAMAFSPFGNLYIADSDSRRV 1886
Cdd:cd05819 238 SDGQFNRPSGLAVDSDGNLYVADTGNNRI 266
|
|
| NHL_like_1 |
cd14953 |
Uncharacterized NHL-repeat domain in bacterial proteins; This bacterial family of NHL-repeat ... |
1732-1927 |
1.63e-18 |
|
Uncharacterized NHL-repeat domain in bacterial proteins; This bacterial family of NHL-repeat domains is found in a variety of domain architectures. The NHL (NCL-1, HT2A and LIN-41) repeat is found in multiple tandem copies, typically as 6 instances. It is about 40 residues long and resembles the WD repeat and other beta-propeller structures.
Pssm-ID: 271323 [Multi-domain] Cd Length: 323 Bit Score: 89.51 E-value: 1.63e-18
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 665390891 1732 GDGGPALLARLSHPKGLAIAADRTMYIADGTN--IRAVDPKGVIHTLI--GHHGHHNHWSPApcsgtlmanqAQLQWPTG 1807
Cdd:cd14953 12 FSGGGGTAARFNSPSGVAVDAAGNLYVADRGNhrIRKITPDGVVTTVAgtGTAGFADGGGAA----------AQFNTPSG 81
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 665390891 1808 LALSPlDGSLhFIDDRL---VLRLTSDMKIRVVAGTplhCSNGGQDGrvnkTGADN-VLGTVLAMAFSPFGNLYIADsds 1883
Cdd:cd14953 82 VAVDA-AGNL-YVADTGnhrIRKITPDGVVSTLAGT---GTAGFSDD----GGATAaQFNYPTGVAVDAAGNLYVAD--- 149
|
170 180 190 200
....*....|....*....|....*....|....*....|....
gi 665390891 1884 RRVNSIRVVDTAGNMRYFAgkqeGTGSQtcdcaiGGGSNGSATN 1927
Cdd:cd14953 150 TGNHRIRKITPDGVVTTVA----GTGGA------GYAGDGPATA 183
|
|
| NHL |
cd05819 |
NHL repeat unit of beta-propeller proteins; The NHL(NCL-1, HT2A and LIN-41)-repeat is found in ... |
1626-1911 |
2.46e-16 |
|
NHL repeat unit of beta-propeller proteins; The NHL(NCL-1, HT2A and LIN-41)-repeat is found in multiple tandem copies, typically as 6 instances. It is about 40 residues long and resembles the WD repeat and other beta-propeller structures. The repeats have a catalytic activity in Peptidyl-glycine alpha-amidating monooxygenase; proteolysis has shown that the Peptidyl-alpha-hydroxyglycine alpha-amidating lyase (PAL) activity is localized to the repeats. Tripartite motif-containing protein 32 interacts with the activation domain of Tat. This interaction is mediated by the NHL repeats.
Pssm-ID: 271320 [Multi-domain] Cd Length: 269 Bit Score: 81.98 E-value: 2.46e-16
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 665390891 1626 KDAKLLTPIALATGPDGSLYVGDF--NLVRRITPDGKVYTILQLSAT---QVSYQYYLAVSPaDGHLYISDPERHQILRL 1700
Cdd:cd05819 3 GPGELNNPQGIAVDSSGNIYVADTgnNRIQVFDPDGNFITSFGSFGSgdgQFNEPAGVAVDS-DGNLYVADTGNHRIQKF 81
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 665390891 1701 vrlekvkdpSINSDPVVGSGqrcIPGDegncGDGGpallarLSHPKGLAIAADRTMYIADGTN--IRAVDPKGVIHTLIG 1778
Cdd:cd05819 82 ---------DPDGNFLASFG---GSGD----GDGE------FNGPRGIAVDSSGNIYVADTGNhrIQKFDPDGEFLTTFG 139
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 665390891 1779 HHGhhnhwspapcsgtlmANQAQLQWPTGLALSPlDGSLhFIDDRLVLRltsdmkIRVVAgtplhcSNGGQDGRVNKTGA 1858
Cdd:cd05819 140 SGG---------------SGPGQFNGPTGVAVDS-DGNI-YVADTGNHR------IQVFD------PDGNFLTTFGSTGT 190
|
250 260 270 280 290
....*....|....*....|....*....|....*....|....*....|....
gi 665390891 1859 -DNVLGTVLAMAFSPFGNLYIADSDSRRvnsIRVVDTAGNMRYFAGKQEGTGSQ 1911
Cdd:cd05819 191 gPGQFNYPTGIAVDSDGNIYVADSGNNR---VQVFDPDGAGFGGNGNFLGSDGQ 241
|
|
| RHS_core |
NF041261 |
RHS element core protein; |
2450-2902 |
5.06e-14 |
|
RHS element core protein;
Pssm-ID: 469161 [Multi-domain] Cd Length: 1261 Bit Score: 78.89 E-value: 5.06e-14
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 665390891 2450 WAWGPA-ELKYSYDRHGllseitSQqdgIVSFVYNDWNLVSEIG--LASQRKFVLQYDDAGGLRHVVLPSGTRHSFSMQT 2526
Cdd:NF041261 322 YTYTEAgELLAVYDRSN------TQ---VRAFTYDAQHPGRMVAhrYAGRPEMCYRYDDTGRVTEQLNPAGLSYRYQYEQ 392
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 665390891 2527 SigfiRCTYTPPGSTRAYLqhYSHAGALLQTILP---GDGARIVYRYNAAGQLTEVVHGDGR-SEFQYNEATGMPSTVSH 2602
Cdd:NF041261 393 D----RITITDSLNRREVL--HTEGEGGLKRVVKkehADGSVTRSGYDAAGRLTAQTDAAGRrTEYSLNVVSGDITDITT 466
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 665390891 2603 TE-RELEYRWDfeyaagllaeERIDYVAKTGLSNAKFSYEYDSQLRVVALQGRIGgqslPTQAFAYD-PRTGRPSLIG-- 2678
Cdd:NF041261 467 PDgRETKFYYN----------DGNQLTSVTSPDGLESRREYDEPGRLVSETSRSG----ETTRYRYDdPHSELPATTTda 532
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 665390891 2679 -----QFRFSQPAQnQTQLHDGTASFTRTVDGRFQTQrmaLAIHRLEVFRMEFSYGVHGRISQTRtytrnmavNSYTNVK 2753
Cdd:NF041261 533 tgstkQMTWSRYGQ-LLAFTDCSGYQTRYEYDRFGQM---TAVHREEGISTYRRYDNRGQLTSVK--------DAQGRET 600
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 665390891 2754 NYTWDCDGQLVGVEAqePWGFR----YDDNGNLLSLTYRGNTIPMEYNAQDRIVKF-----GEGQYKYDARGLVAQ---- 2820
Cdd:NF041261 601 RYEYNAAGDLTAVIT--PDGNRsetqYDAWGKAVSTTQGGLTRSMEYDAAGRITTLtnengSHSTFLYDALDRLVQqrgf 678
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 665390891 2821 NAREERFHYNTQGLLVRASKRGrFDVRYYYDHLKRLTTRKDNFGNVTQFFYTNQQRPYEVSQIyspRDGKLMSL--TYDD 2898
Cdd:NF041261 679 DGRTQRYHYDLTGKLTQSEDEG-LVTLWHYDESDRITHRTVNGEPAEQWQYDEHGWLTDISHL---SEGHRVAVhyGYDD 754
|
....
gi 665390891 2899 VGHL 2902
Cdd:NF041261 755 KGRL 758
|
|
| NHL |
cd05819 |
NHL repeat unit of beta-propeller proteins; The NHL(NCL-1, HT2A and LIN-41)-repeat is found in ... |
1626-1817 |
7.92e-13 |
|
NHL repeat unit of beta-propeller proteins; The NHL(NCL-1, HT2A and LIN-41)-repeat is found in multiple tandem copies, typically as 6 instances. It is about 40 residues long and resembles the WD repeat and other beta-propeller structures. The repeats have a catalytic activity in Peptidyl-glycine alpha-amidating monooxygenase; proteolysis has shown that the Peptidyl-alpha-hydroxyglycine alpha-amidating lyase (PAL) activity is localized to the repeats. Tripartite motif-containing protein 32 interacts with the activation domain of Tat. This interaction is mediated by the NHL repeats.
Pssm-ID: 271320 [Multi-domain] Cd Length: 269 Bit Score: 71.58 E-value: 7.92e-13
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 665390891 1626 KDAKLLTPIALATGPDGSLYVGDF--NLVRRITPDGKVYTIL---QLSATQVSYQYYLAVSPaDGHLYISDPERHQILRL 1700
Cdd:cd05819 97 GDGEFNGPRGIAVDSSGNIYVADTgnHRIQKFDPDGEFLTTFgsgGSGPGQFNGPTGVAVDS-DGNIYVADTGNHRIQVF 175
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 665390891 1701 vrlekvkDPSINSDPVVGSGqrcipgdegncGDGGpallARLSHPKGLAIAADRTMYIADGTN--IRAVDPKGVIHTlig 1778
Cdd:cd05819 176 -------DPDGNFLTTFGST-----------GTGP----GQFNYPTGIAVDSDGNIYVADSGNnrVQVFDPDGAGFG--- 230
|
170 180 190
....*....|....*....|....*....|....*....
gi 665390891 1779 hhghhnhwspapCSGTLMANQAQLQWPTGLALSPlDGSL 1817
Cdd:cd05819 231 ------------GNGNFLGSDGQFNRPSGLAVDS-DGNL 256
|
|
| Vgb |
COG4257 |
Streptogramin lyase [Defense mechanisms]; |
1627-1902 |
1.02e-11 |
|
Streptogramin lyase [Defense mechanisms];
Pssm-ID: 443399 [Multi-domain] Cd Length: 270 Bit Score: 68.12 E-value: 1.02e-11
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 665390891 1627 DAKLLTPIALATGPDGSLYVGDF--NLVRRITPDGKVYTILQLSATQvSYQYYLAVSPaDGHLYISDPERHQILRLvrle 1704
Cdd:COG4257 55 LGGGSGPHGIAVDPDGNLWFTDNgnNRIGRIDPKTGEITTFALPGGG-SNPHGIAFDP-DGNLWFTDQGGNRIGRL---- 128
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 665390891 1705 kvkdpsinsDPVVGSgqrcIPGDEGNCGDGGPAllarlshpkGLAIAADRTMYIAD-GTN-IRAVDPK-GVIHTLighhg 1781
Cdd:COG4257 129 ---------DPATGE----VTEFPLPTGGAGPY---------GIAVDPDGNLWVTDfGANaIGRIDPDtGTLTEY----- 181
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 665390891 1782 hhnhwspapcsgtlmANQAQLQWPTGLALSPlDGSLHFIDdrlvlrltsdmkirvvagtplhcSNGGQDGRVN-KTGADN 1860
Cdd:COG4257 182 ---------------ALPTPGAGPRGLAVDP-DGNLWVAD-----------------------TGSGRIGRFDpKTGTVT 222
|
250 260 270 280
....*....|....*....|....*....|....*....|....*...
gi 665390891 1861 VLGTVL------AMAFSPFGNLYIADSDSrrvNSIRVVDTAGNMRYFA 1902
Cdd:COG4257 223 EYPLPGggarpyGVAVDGDGRVWFAESGA---NRIVRFDPDTELTEYV 267
|
|
| RHS_core |
NF041261 |
RHS element core protein; |
2223-2860 |
3.71e-11 |
|
RHS element core protein;
Pssm-ID: 469161 [Multi-domain] Cd Length: 1261 Bit Score: 69.65 E-value: 3.71e-11
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 665390891 2223 RSSGGETYIYQYDEFGRVTGMILPSGeiVRITSQLADSQgLTVyvhasVESLFSRERIAGEANellvlGGVRSTFLKRgq 2302
Cdd:NF041261 358 RYAGRPEMCYRYDDTGRVTEQLNPAG--LSYRYQYEQDR-ITI-----TDSLNRREVLHTEGE-----GGLKRVVKKE-- 422
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 665390891 2303 aHADAELKANntlvihgdngvvvEASAVARhplLEAalpveaemlamwshQSVTMGEGLTNSMYSVYSLVGDVRNPQQTL 2382
Cdd:NF041261 423 -HADGSVTRS-------------GYDAAGR---LTA--------------QTDAAGRRTEYSLNVVSGDITDITTPDGRE 471
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 665390891 2383 NREIWVNQSRVIGV----------EFDQfTNRETFYDARRTPILIVAYD--QSGLPKSYYPTNGYPVNITYDRFNRVEGW 2450
Cdd:NF041261 472 TKFYYNDGNQLTSVtspdglesrrEYDE-PGRLVSETSRSGETTRYRYDdpHSELPATTTDATGSTKQMTWSRYGQLLAF 550
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 665390891 2451 A-WGPAELKYSYDRHGLLSEItSQQDGIVSF-VYNDWNLVSEIGLASQRKFVLQYDDAGGLRHVVLPSGTRhSFSMQTSI 2528
Cdd:NF041261 551 TdCSGYQTRYEYDRFGQMTAV-HREEGISTYrRYDNRGQLTSVKDAQGRETRYEYNAAGDLTAVITPDGNR-SETQYDAW 628
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 665390891 2529 GFIRCTyTPPGSTRAylQHYSHAGALLqTILPGDGARIVYRYNAAGQLTEVVHGDGRSEFQYNEATGmpsTVSHTERE-L 2607
Cdd:NF041261 629 GKAVST-TQGGLTRS--MEYDAAGRIT-TLTNENGSHSTFLYDALDRLVQQRGFDGRTQRYHYDLTG---KLTQSEDEgL 701
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 665390891 2608 EYRWDFEyaagllAEERIDYVAKTGLSNAKFSYE---------YDSQLRVVAL------QGRIGGQSLPTQafayDPRTG 2672
Cdd:NF041261 702 VTLWHYD------ESDRITHRTVNGEPAEQWQYDehgwltdisHLSEGHRVAVhygyddKGRLTGERQTVE----NPETG 771
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 665390891 2673 RpsLIGQFR----FSQPAQNQTQLHDGTASFTRTVDGRFQTQRMALA-----------IHRlEVFRMEFSYGVHGRISQT 2737
Cdd:NF041261 772 E--LLWQHEtghaYNEQGLANRVTPDSLPPVEWLTYGSGYLAGMKLGgtplveytrdrLHR-ETVRSFGGAGSNAAYELT 848
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 665390891 2738 RTYT-----RNMAVNSYTNVKNYTWDCDGQLVGVEA-QEPWGFRYDDNGNLLS-------LTYR--------GNTIP--- 2793
Cdd:NF041261 849 TAYTpagqlQSQHLNSLVYDRDYTWNDNGDLVRISGpRQTREYGYSATGRLTGvhttaanLDIRipyatdpaGNRLPdpe 928
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 665390891 2794 ------MEYNAQDRIVKFGEGQYKYDARGLVAQ-------------NAREERFHYNTQGLLVRASK----RGRFDVRYYY 2850
Cdd:NF041261 929 lhpdstLTAWPDNRIAEDAHYVYRYDEYGRLTEktdripegvirtdDERTHHYHYDSQHRLVFYTRiqhgEPLVESRYLY 1008
|
730
....*....|
gi 665390891 2851 DHLKRLTTRK 2860
Cdd:NF041261 1009 DPLGRRMAKR 1018
|
|
| acid_disulf_rpt |
NF033662 |
acidic double-disulfide repeat; The acidic double-disulfide repeat is an Asp-rich repeat with ... |
1199-1225 |
3.04e-09 |
|
acidic double-disulfide repeat; The acidic double-disulfide repeat is an Asp-rich repeat with four nearly invariant Cys residues in a repeat length of about 35 amino acids.
Pssm-ID: 411265 [Multi-domain] Cd Length: 32 Bit Score: 54.44 E-value: 3.04e-09
10 20
....*....|....*....|....*..
gi 665390891 1199 NCKDNIDNDGDGMTDCSDSECCSHPAC 1225
Cdd:NF033662 6 TCSDGIDNDGDGLTDCADPDCAGNPVC 32
|
|
| Rhs_assc_core |
TIGR03696 |
RHS repeat-associated core domain; This model represents a conserved unique core sequence ... |
2939-3015 |
3.57e-08 |
|
RHS repeat-associated core domain; This model represents a conserved unique core sequence shared by large numbers of proteins. It is occasional in the Archaea Methanosarcina barkeri) but common in bacteria and eukaryotes. Most fall into two large classes. One class consists of long proteins in which two classes of repeats are abundant: an FG-GAP repeat (pfam01839) class, and an RHS repeat (pfam05593) or YD repeat (TIGR01643). This class includes secreted bacterial insecticidal toxins and intercellular signalling proteins such as the teneurins in animals. The other class consists of uncharacterized proteins shorter than 400 amino acids, where this core domain of about 75 amino acids tends to occur in the N-terminal half. Over twenty such proteins are found in Pseudomonas putida alone; little sequence similarity or repeat structure is found among these proteins outside the region modeled by this domain.
Pssm-ID: 274730 [Multi-domain] Cd Length: 77 Bit Score: 52.89 E-value: 3.57e-08
10 20 30 40 50 60 70
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 665390891 2939 SPFGHIVYDSNPyLYLPIDFCGGILDQVTTLVHMGdGRVYDPLIGQWMSPDwqrvaeRIITPTRLHLYRFNGNDPIN 3015
Cdd:TIGR03696 2 DPYGEVLSESGA-APNPLRFTGQYYDAETGLYYNG-ARYYDPELGRFLSPD------PIGLGGGLNLYAYVGNNPVN 70
|
|
| NHL_like_6 |
cd14962 |
Uncharacterized NHL-repeat domain in bacterial proteins; The NHL (NCL-1, HT2A and LIN-41) ... |
1623-1781 |
6.41e-08 |
|
Uncharacterized NHL-repeat domain in bacterial proteins; The NHL (NCL-1, HT2A and LIN-41) repeat is found in multiple tandem copies, typically as 6 instances. It is about 40 residues long and resembles the WD repeat and other beta-propeller structures.
Pssm-ID: 271332 [Multi-domain] Cd Length: 271 Bit Score: 56.83 E-value: 6.41e-08
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 665390891 1623 GVAKDAKLLTPIALATGPDGSLYVGDFNL--VRRITPDGK-VYTI----LQLSATQVsyqyylAVSPADGHLYISDPERH 1695
Cdd:cd14962 49 GNAGPNRFVSPIGVAIDANGNLYVSDAELgkVFVFDRDGKfLRAIgagaLFKRPTGI------AVDPAGKRLYVVDTLAH 122
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 665390891 1696 QIlrlvrleKVKDPSinsdpvvGSGQRCIpgdeGNCGDGGpallARLSHPKGLAIAADRTMYIADGTNIR--AVDPKGVI 1773
Cdd:cd14962 123 KV-------KVFDLD-------GRLLFDI----GKRGSGP----GEFNLPTDLAVDRDGNLYVTDTMNFRvqIFDADGKF 180
|
....*...
gi 665390891 1774 HTLIGHHG 1781
Cdd:cd14962 181 LRSFGERG 188
|
|
| NHL_like_3 |
cd14956 |
Uncharacterized NHL-repeat domain in bacterial proteins; The NHL (NCL-1, HT2A and LIN-41) ... |
1627-1886 |
9.08e-08 |
|
Uncharacterized NHL-repeat domain in bacterial proteins; The NHL (NCL-1, HT2A and LIN-41) repeat is found in multiple tandem copies, typically as 6 instances. It is about 40 residues long and resembles the WD repeat and other beta-propeller structures.
Pssm-ID: 271326 [Multi-domain] Cd Length: 274 Bit Score: 56.52 E-value: 9.08e-08
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 665390891 1627 DAKLLTPIALATGPDGSLYVGDF--NLVRRITPDGKVYTILQLSAT---QVSYQYYLAVSPaDGHLYISDPERHQILRLv 1701
Cdd:cd14956 56 PGQFGRPRGLAVDKDGWLYVADYwgDRIQVFTLTGELQTIGGSSGSgpgQFNAPRGVAVDA-DGNLYVADFGNQRIQKF- 133
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 665390891 1702 rlekvkdpsinsDP---VVGS-GQRCIPGDEGNcgdggpallarlsHPKGLAIAADRTMYIADGTN--IRAVDPKGVIHT 1775
Cdd:cd14956 134 ------------DPdgsFLRQwGGTGIEPGSFN-------------YPRGVAVDPDGTLYVADTYNdrIQVFDNDGAFLR 188
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 665390891 1776 LIGHHGHHNHWspapcsgtlmanqaqLQWPTGLALSPlDGSLHFID---DRlVLRLTSDMKIRVVAGTPlhcsnGGQDGR 1852
Cdd:cd14956 189 KWGGRGTGPGQ---------------FNYPYGIAIDP-DGNVFVADfgnNR-IQKFTADGTFLTSWGSP-----GTGPGQ 246
|
250 260 270
....*....|....*....|....*....|....
gi 665390891 1853 vnktgadnvLGTVLAMAFSPFGNLYIADSDSRRV 1886
Cdd:cd14956 247 ---------FKNPWGVVVDADGTVYVADSNNNRV 271
|
|
| NHL-2_like |
cd14951 |
NHL repeat domain of NHL repeat-containing protein 2 and similar proteins; NHL ... |
1729-1897 |
2.47e-07 |
|
NHL repeat domain of NHL repeat-containing protein 2 and similar proteins; NHL repeat-containing protein 2 (NHLRC2) and related bacterial proteins; members of this eukaryotic and bacterial family are uncharacterized, the NHL repeat domain is found C-terminally of a thioredoxin domain. The NHL (NCL-1, HT2A and LIN-41) repeat is found in multiple tandem copies, typically as 6 instances. It is about 40 residues long and resembles the WD repeat and other beta-propeller structures.
Pssm-ID: 271321 [Multi-domain] Cd Length: 334 Bit Score: 55.66 E-value: 2.47e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 665390891 1729 GNCG--DGGPALlARLSHPKGLAIAADRTMYIADGTN--IRAVDP-KGVIHTL--IGHHGHHNhwspapcSGTLMANQAQ 1801
Cdd:cd14951 4 GERGlkDGSFAE-ASFNEPQGLALLPGNILYVADTENhaLRKIDLeTGTVTTLagTGEQGRDG-------EGGGPGREQP 75
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 665390891 1802 LQwptglalSPLDGSLHFIDDRLVLR----------LTSDMKIRVVAGTplhcsngGQDGRVNKTGADNvlgTVLA---- 1867
Cdd:cd14951 76 LS-------SPWDVAWGPEDDILYIAmagthqiwayDLDTGTCRVFAGS-------GNEGNRNGPYPHE---AWFAqpsg 138
|
170 180 190
....*....|....*....|....*....|
gi 665390891 1868 MAFSPFGNLYIADSDSrrvNSIRVVDTAGN 1897
Cdd:cd14951 139 LSLAGWGELFVADSES---SAIRAVSLKDG 165
|
|
| EGF_2 |
pfam07974 |
EGF-like domain; This family contains EGF domains found in a variety of extracellular proteins. |
1034-1057 |
2.39e-05 |
|
EGF-like domain; This family contains EGF domains found in a variety of extracellular proteins.
Pssm-ID: 400365 Cd Length: 26 Bit Score: 43.49 E-value: 2.39e-05
10 20
....*....|....*....|....*.
gi 665390891 1034 LCSGHGTCVA--GQCYCKAGWQGEDC 1057
Cdd:pfam07974 1 ICSGRGTCVNqcGKCVCDSGYQGATC 26
|
|
| Vgb |
COG4257 |
Streptogramin lyase [Defense mechanisms]; |
1676-1909 |
5.35e-05 |
|
Streptogramin lyase [Defense mechanisms];
Pssm-ID: 443399 [Multi-domain] Cd Length: 270 Bit Score: 47.71 E-value: 5.35e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 665390891 1676 YYLAVSPaDGHLYISDPERHQILRLvrlekvkdpsinsDPVVGSGQRcipgdegncgdggpALLARLSHPKGLAIAADRT 1755
Cdd:COG4257 20 RDVAVDP-DGAVWFTDQGGGRIGRL-------------DPATGEFTE--------------YPLGGGSGPHGIAVDPDGN 71
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 665390891 1756 MYIADGTN--IRAVDPK-GVIHTLIGhhghhnhwsPAPCSGtlmanqaqlqwPTGLALSPlDGSLHFIDDR--LVLRLT- 1829
Cdd:COG4257 72 LWFTDNGNnrIGRIDPKtGEITTFAL---------PGGGSN-----------PHGIAFDP-DGNLWFTDQGgnRIGRLDp 130
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 665390891 1830 SDMKIRVVAGTplhcSNGGQDGrvnktgadnvlgtvlAMAFSPFGNLYIADsdsRRVNSIRVVDTA-GNMRYFAGKQEGT 1908
Cdd:COG4257 131 ATGEVTEFPLP----TGGAGPY---------------GIAVDPDGNLWVTD---FGANAIGRIDPDtGTLTEYALPTPGA 188
|
.
gi 665390891 1909 G 1909
Cdd:COG4257 189 G 189
|
|
| NHL-2_like |
cd14951 |
NHL repeat domain of NHL repeat-containing protein 2 and similar proteins; NHL ... |
1623-1705 |
8.16e-05 |
|
NHL repeat domain of NHL repeat-containing protein 2 and similar proteins; NHL repeat-containing protein 2 (NHLRC2) and related bacterial proteins; members of this eukaryotic and bacterial family are uncharacterized, the NHL repeat domain is found C-terminally of a thioredoxin domain. The NHL (NCL-1, HT2A and LIN-41) repeat is found in multiple tandem copies, typically as 6 instances. It is about 40 residues long and resembles the WD repeat and other beta-propeller structures.
Pssm-ID: 271321 [Multi-domain] Cd Length: 334 Bit Score: 47.96 E-value: 8.16e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 665390891 1623 GVAKDAKLLTPIALATGPDGSLYVGD-FN-LVRRITPD-GKVYTI---LQLSATQVSYQYY----LAVSPaDGHLYISDP 1692
Cdd:cd14951 188 GPGAEALLQHPLGVAALPDGSVYVADtYNhKIKRVDPAtGEVSTLagtGKAGYKDLEAQFSepsgLVVDG-DGRLYVADT 266
|
90
....*....|...
gi 665390891 1693 ERHQIlRLVRLEK 1705
Cdd:cd14951 267 NNHRI-RRLDLPT 278
|
|
| NHL-2_like |
cd14951 |
NHL repeat domain of NHL repeat-containing protein 2 and similar proteins; NHL ... |
1678-1817 |
8.38e-05 |
|
NHL repeat domain of NHL repeat-containing protein 2 and similar proteins; NHL repeat-containing protein 2 (NHLRC2) and related bacterial proteins; members of this eukaryotic and bacterial family are uncharacterized, the NHL repeat domain is found C-terminally of a thioredoxin domain. The NHL (NCL-1, HT2A and LIN-41) repeat is found in multiple tandem copies, typically as 6 instances. It is about 40 residues long and resembles the WD repeat and other beta-propeller structures.
Pssm-ID: 271321 [Multi-domain] Cd Length: 334 Bit Score: 47.57 E-value: 8.38e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 665390891 1678 LAVSPaDGHLYISDPERhQILRLVRLEKVKDPSINSDPVVGSGQrcipgdeGNCGD-GGPALLARLSHPKGLAIAADRTM 1756
Cdd:cd14951 139 LSLAG-WGELFVADSES-SAIRAVSLKDGGVKTLVGGTRVGTGL-------FDFGDrDGPGAEALLQHPLGVAALPDGSV 209
|
90 100 110 120 130 140
....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 665390891 1757 YIADGTN--IRAVDPK-GVIHTLIghhghhnhwspapcsGTLMAN----QAQLQWPTGLALSPlDGSL 1817
Cdd:cd14951 210 YVADTYNhkIKRVDPAtGEVSTLA---------------GTGKAGykdlEAQFSEPSGLVVDG-DGRL 261
|
|
| YvrE |
COG3386 |
Sugar lactone lactonase YvrE [Carbohydrate transport and metabolism]; Sugar lactone lactonase ... |
1683-1909 |
3.44e-04 |
|
Sugar lactone lactonase YvrE [Carbohydrate transport and metabolism]; Sugar lactone lactonase YvrE is part of the Pathway/BioSystem: Non-phosphorylated Entner-Doudoroff pathway
Pssm-ID: 442613 [Multi-domain] Cd Length: 266 Bit Score: 45.27 E-value: 3.44e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 665390891 1683 ADGHLYISDPERHQILRLvrlekvkDPSinsdpvvGSGQRCIPGDEGncgdggpallarlsHPKGLAIAADRTMYIAD-G 1761
Cdd:COG3386 17 PDGRLYWVDIPGGRIHRY-------DPD-------GGAVEVFAEPSG--------------RPNGLAFDPDGRLLVADhG 68
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 665390891 1762 TNIRAVDPK-GVIHTLIGHHGHhnhwspapcsgtlmanqaQLQWPTGLALSPlDGSL------HFIDDRLVLRLTSDMKI 1834
Cdd:COG3386 69 RGLVRFDPAdGEVTVLADEYGK------------------PLNRPNDGVVDP-DGRLyftdmgEYLPTGALYRVDPDGSL 129
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 665390891 1835 RVVAgTPLHCSNGgqdgrvnktgadnvlgtvlaMAFSPFGN-LYIADSDSRRVNSIRVVD--TAGNMRYFAGKQEGTG 1909
Cdd:COG3386 130 RVLA-DGLTFPNG--------------------IAFSPDGRtLYVADTGAGRIYRFDLDAdgTLGNRRVFADLPDGPG 186
|
|
| C_rich_MXAN6577 |
NF041328 |
MXAN_6577-like cysteine-rich domain; |
1035-1146 |
3.45e-04 |
|
MXAN_6577-like cysteine-rich domain;
Pssm-ID: 469225 [Multi-domain] Cd Length: 145 Bit Score: 43.59 E-value: 3.45e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 665390891 1035 CSGHGTCVAGQCYCKAGwqGEDCGtidqqvyqclpgcsehgtydletGQCVCERhwTGPD-CSQavCSLDCGRNGVCESG 1113
Cdd:NF041328 49 CGAGQTCVAGACGCGPG--TVACG-----------------------GACVDTA--SDPAhCGA--CGAACAPGQVCEGG 99
|
90 100 110 120
....*....|....*....|....*....|....*....|....*
gi 665390891 1114 KCR--CNSGWT--GNLC-----DQL---PCDSRCSEHGQCKNGTC 1146
Cdd:NF041328 100 ACReaCSEGLTrcGGACvdlatDPLhcgACGVACDPGESCRGGAC 144
|
|
| RHS_core |
NF041261 |
RHS element core protein; |
2118-2248 |
3.93e-04 |
|
RHS element core protein;
Pssm-ID: 469161 [Multi-domain] Cd Length: 1261 Bit Score: 46.53 E-value: 3.93e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 665390891 2118 SSEIYVFNRYGQHVATKDLTSGKTRYSFlysknTSFGRLSTVTDASGnkIQFLRDYSN--VVSSIENTQDHKSEIQINGI 2195
Cdd:NF041261 535 STKQMTWSRYGQLLAFTDCSGYQTRYEY-----DRFGQMTAVHREEG--ISTYRRYDNrgQLTSVKDAQGRETRYEYNAA 607
|
90 100 110 120 130
....*....|....*....|....*....|....*....|....*....|...
gi 665390891 2196 GIMTKLSEKGRQEIELDYDSnTGLLNSRSSGGETYIYQYDEFGRVTGMILPSG 2248
Cdd:NF041261 608 GDLTAVITPDGNRSETQYDA-WGKAVSTTQGGLTRSMEYDAAGRITTLTNENG 659
|
|
| PLN02919 |
PLN02919 |
haloacid dehalogenase-like hydrolase family protein |
1669-1770 |
4.51e-04 |
|
haloacid dehalogenase-like hydrolase family protein
Pssm-ID: 215497 [Multi-domain] Cd Length: 1057 Bit Score: 46.38 E-value: 4.51e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 665390891 1669 ATQVSYQYYLAV-SPADGHLYISDPERHQIlrlvrleKVKDPSINS-DPVVGSGQRCIpgdegncgDGGPALLARLSHPK 1746
Cdd:PLN02919 798 GSEVLLQHPLGVlCAKDGQIYVADSYNHKI-------KKLDPATKRvTTLAGTGKAGF--------KDGKALKAQLSEPA 862
|
90 100
....*....|....*....|....*.
gi 665390891 1747 GLAIAADRTMYIADGTN--IRAVDPK 1770
Cdd:PLN02919 863 GLALGENGRLFVADTNNslIRYLDLN 888
|
|
| YvrE |
COG3386 |
Sugar lactone lactonase YvrE [Carbohydrate transport and metabolism]; Sugar lactone lactonase ... |
1636-1777 |
5.06e-04 |
|
Sugar lactone lactonase YvrE [Carbohydrate transport and metabolism]; Sugar lactone lactonase YvrE is part of the Pathway/BioSystem: Non-phosphorylated Entner-Doudoroff pathway
Pssm-ID: 442613 [Multi-domain] Cd Length: 266 Bit Score: 44.88 E-value: 5.06e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 665390891 1636 LATGPDGSLYVGDFNLVR------RITPDGKVYTIlqlsATQVSYQYYLAVSPADGHLYISDPERHQILRLvrlekvkdp 1709
Cdd:COG3386 98 GVVDPDGRLYFTDMGEYLptgalyRVDPDGSLRVL----ADGLTFPNGIAFSPDGRTLYVADTGAGRIYRF--------- 164
|
90 100 110 120 130 140 150
....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 665390891 1710 SINSDPVVGSGQRCIPGDEgncGDGGPAllarlshpkGLAIAADRTMYIA--DGTNIRAVDPKGVIHTLI 1777
Cdd:COG3386 165 DLDADGTLGNRRVFADLPD---GPGGPD---------GLAVDADGNLWVAlwGGGGVVRFDPDGELLGRI 222
|
|
| NHL |
cd05819 |
NHL repeat unit of beta-propeller proteins; The NHL(NCL-1, HT2A and LIN-41)-repeat is found in ... |
1622-1700 |
5.33e-04 |
|
NHL repeat unit of beta-propeller proteins; The NHL(NCL-1, HT2A and LIN-41)-repeat is found in multiple tandem copies, typically as 6 instances. It is about 40 residues long and resembles the WD repeat and other beta-propeller structures. The repeats have a catalytic activity in Peptidyl-glycine alpha-amidating monooxygenase; proteolysis has shown that the Peptidyl-alpha-hydroxyglycine alpha-amidating lyase (PAL) activity is localized to the repeats. Tripartite motif-containing protein 32 interacts with the activation domain of Tat. This interaction is mediated by the NHL repeats.
Pssm-ID: 271320 [Multi-domain] Cd Length: 269 Bit Score: 44.62 E-value: 5.33e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 665390891 1622 NGVAKDAKLLTPIALATGPDGSLYVGDF--NLVRRITPDGKVYTIL---QLSATQVSYQYYLAVSPaDGHLYISDPERHQ 1696
Cdd:cd05819 187 STGTGPGQFNYPTGIAVDSDGNIYVADSgnNRVQVFDPDGAGFGGNgnfLGSDGQFNRPSGLAVDS-DGNLYVADTGNNR 265
|
....
gi 665390891 1697 ILRL 1700
Cdd:cd05819 266 IQVF 269
|
|
| DSL |
pfam01414 |
Delta serrate ligand; This family has been redefined to correspond to the EGF-like domain ... |
1117-1160 |
6.81e-04 |
|
Delta serrate ligand; This family has been redefined to correspond to the EGF-like domain defined by structure.
Pssm-ID: 460202 Cd Length: 46 Bit Score: 39.91 E-value: 6.81e-04
10 20 30 40 50
....*....|....*....|....*....|....*....|....*....|..
gi 665390891 1117 CNSGWTGNLCDQLpCDSR--------CSEHGQCkngtcVCSQGWNGRHCTLP 1160
Cdd:pfam01414 1 CDENYYGSTCSKF-CRPRddkfghytCDANGNK-----VCLPGWTGPYCDKP 46
|
|
| EGF_2 |
pfam07974 |
EGF-like domain; This family contains EGF domains found in a variety of extracellular proteins. |
937-960 |
7.53e-04 |
|
EGF-like domain; This family contains EGF domains found in a variety of extracellular proteins.
Pssm-ID: 400365 Cd Length: 26 Bit Score: 39.25 E-value: 7.53e-04
10 20
....*....|....*....|....*.
gi 665390891 937 DCSGRGSCYL--GKCDCIDGYQGVDC 960
Cdd:pfam07974 1 ICSGRGTCVNqcGKCVCDSGYQGATC 26
|
|
| EGF_2 |
pfam07974 |
EGF-like domain; This family contains EGF domains found in a variety of extracellular proteins. |
1071-1095 |
1.02e-03 |
|
EGF-like domain; This family contains EGF domains found in a variety of extracellular proteins.
Pssm-ID: 400365 Cd Length: 26 Bit Score: 38.87 E-value: 1.02e-03
10 20
....*....|....*....|....*
gi 665390891 1071 CSEHGTYDLETGQCVCERHWTGPDC 1095
Cdd:pfam07974 2 CSGRGTCVNQCGKCVCDSGYQGATC 26
|
|
| YliI |
COG2133 |
Glucose/arabinose dehydrogenase, beta-propeller fold [Carbohydrate transport and metabolism]; |
1633-1764 |
1.23e-03 |
|
Glucose/arabinose dehydrogenase, beta-propeller fold [Carbohydrate transport and metabolism];
Pssm-ID: 441736 [Multi-domain] Cd Length: 365 Bit Score: 44.15 E-value: 1.23e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 665390891 1633 PIALATGPDGSLYVGD-FNLVRRITPDGKVYTILQLSATQVSYQY---YLAVSP---ADGHLYI--SDPERHQiLRLVRL 1703
Cdd:COG2133 39 PWGLAFLPDGRLLVTErAGRIRLLDDDGKLSTPVADLPVFAGGEGgllGVALDPdfaTNGYLYVayTDPGGAG-TRVARF 117
|
90 100 110 120 130 140
....*....|....*....|....*....|....*....|....*....|....*....|....
gi 665390891 1704 EKVKDPSINSDPVVGSGqrcIPGDEGNcgdggpallarlsHP-KGLAIAADRTMYIA--DGTNI 1764
Cdd:COG2133 118 TLSDGDTLTSEEVILDG---LPAGGGN-------------HNgGRLAFGPDGKLYVSvgDRGNA 165
|
|
| EGF_2 |
pfam07974 |
EGF-like domain; This family contains EGF domains found in a variety of extracellular proteins. |
1003-1025 |
1.64e-03 |
|
EGF-like domain; This family contains EGF domains found in a variety of extracellular proteins.
Pssm-ID: 400365 Cd Length: 26 Bit Score: 38.10 E-value: 1.64e-03
10 20
....*....|....*....|....*
gi 665390891 1003 CSSHGRCI--EGECHCERGWKGPYC 1025
Cdd:pfam07974 2 CSGRGTCVnqCGKCVCDSGYQGATC 26
|
|
| EGF_2 |
pfam07974 |
EGF-like domain; This family contains EGF domains found in a variety of extracellular proteins. |
1135-1157 |
2.35e-03 |
|
EGF-like domain; This family contains EGF domains found in a variety of extracellular proteins.
Pssm-ID: 400365 Cd Length: 26 Bit Score: 37.71 E-value: 2.35e-03
10 20
....*....|....*....|....*
gi 665390891 1135 CSEHGQC--KNGTCVCSQGWNGRHC 1157
Cdd:pfam07974 2 CSGRGTCvnQCGKCVCDSGYQGATC 26
|
|
| RHS_repeat |
pfam05593 |
RHS Repeat; RHS proteins contain extended repeat regions. These repeats often appear to be ... |
2213-2249 |
2.38e-03 |
|
RHS Repeat; RHS proteins contain extended repeat regions. These repeats often appear to be involved in ligand binding. Note that this model may not find all the repeats in a protein and that it covers two RHS repeats. The 3D structure of an RHS-repeat-containing protein (the B and C components of an ABC toxin complex) has been determined. The RHS repeats form an extended strip of beta-sheet that spirals around to form a hollow shell, encapsulating the variable C-terminal domain.
Pssm-ID: 461685 [Multi-domain] Cd Length: 37 Bit Score: 37.96 E-value: 2.38e-03
10 20 30
....*....|....*....|....*....|....*..
gi 665390891 2213 YDSNTGLLNSRSSGGETYIYQYDEFGRVTGMILPSGE 2249
Cdd:pfam05593 1 YDAAGRLTSVTDPDGRVTTYTYDAAGRLTAVTDPDGT 37
|
|
| EGF_2 |
pfam07974 |
EGF-like domain; This family contains EGF domains found in a variety of extracellular proteins. |
1103-1126 |
2.40e-03 |
|
EGF-like domain; This family contains EGF domains found in a variety of extracellular proteins.
Pssm-ID: 400365 Cd Length: 26 Bit Score: 37.71 E-value: 2.40e-03
10 20
....*....|....*....|....*.
gi 665390891 1103 DCGRNGVCES--GKCRCNSGWTGNLC 1126
Cdd:pfam07974 1 ICSGRGTCVNqcGKCVCDSGYQGATC 26
|
|
| EGF_CA |
cd00054 |
Calcium-binding EGF-like domain, present in a large number of membrane-bound and extracellular ... |
1163-1192 |
3.45e-03 |
|
Calcium-binding EGF-like domain, present in a large number of membrane-bound and extracellular (mostly animal) proteins. Many of these proteins require calcium for their biological function and calcium-binding sites have been found to be located at the N-terminus of particular EGF-like domains; calcium-binding may be crucial for numerous protein-protein interactions. Six conserved core cysteines form three disulfide bridges as in non calcium-binding EGF domains, whose structures are very similar. EGF_CA can be found in tandem repeat arrangements.
Pssm-ID: 238011 Cd Length: 38 Bit Score: 37.62 E-value: 3.45e-03
10 20 30
....*....|....*....|....*....|
gi 665390891 1163 ENGCSRHGQCTLENGEYRCDCIEGWAGRDC 1192
Cdd:cd00054 8 GNPCQNGGTCVNTVGSYRCSCPPGYTGRNC 37
|
|
| EGF_Tenascin |
pfam18720 |
Tenascin EGF domain; This entry represents the EGF-like domains found in tenascin proteins. |
934-961 |
5.32e-03 |
|
Tenascin EGF domain; This entry represents the EGF-like domains found in tenascin proteins.
Pssm-ID: 376143 Cd Length: 29 Bit Score: 36.89 E-value: 5.32e-03
10 20
....*....|....*....|....*...
gi 665390891 934 CPNDCSGRGSCYLGKCDCIDGYQGVDCS 961
Cdd:pfam18720 2 CPLGCSSRGVCVDGQCICDSEYSGDDCS 29
|
|
| DSL |
pfam01414 |
Delta serrate ligand; This family has been redefined to correspond to the EGF-like domain ... |
982-1027 |
5.60e-03 |
|
Delta serrate ligand; This family has been redefined to correspond to the EGF-like domain defined by structure.
Pssm-ID: 460202 Cd Length: 46 Bit Score: 37.22 E-value: 5.60e-03
10 20 30 40 50
....*....|....*....|....*....|....*....|....*....|...
gi 665390891 982 CEEGWKGAECDIpvgECEVPN-------CSSHGRCIegechCERGWKGPYCDQ 1027
Cdd:pfam01414 1 CDENYYGSTCSK---FCRPRDdkfghytCDANGNKV-----CLPGWTGPYCDK 45
|
|
| EGF_CA |
cd00054 |
Calcium-binding EGF-like domain, present in a large number of membrane-bound and extracellular ... |
1131-1158 |
7.00e-03 |
|
Calcium-binding EGF-like domain, present in a large number of membrane-bound and extracellular (mostly animal) proteins. Many of these proteins require calcium for their biological function and calcium-binding sites have been found to be located at the N-terminus of particular EGF-like domains; calcium-binding may be crucial for numerous protein-protein interactions. Six conserved core cysteines form three disulfide bridges as in non calcium-binding EGF domains, whose structures are very similar. EGF_CA can be found in tandem repeat arrangements.
Pssm-ID: 238011 Cd Length: 38 Bit Score: 36.85 E-value: 7.00e-03
10 20 30
....*....|....*....|....*....|....
gi 665390891 1131 CDSR--CSEHGQCKNG----TCVCSQGWNGRHCT 1158
Cdd:cd00054 5 CASGnpCQNGGTCVNTvgsyRCSCPPGYTGRNCE 38
|
|
| EGF |
cd00053 |
Epidermal growth factor domain, found in epidermal growth factor (EGF) presents in a large ... |
1164-1192 |
7.05e-03 |
|
Epidermal growth factor domain, found in epidermal growth factor (EGF) presents in a large number of proteins, mostly animal; the list of proteins currently known to contain one or more copies of an EGF-like pattern is large and varied; the functional significance of EGF-like domains in what appear to be unrelated proteins is not yet clear; a common feature is that these repeats are found in the extracellular domain of membrane-bound proteins or in proteins known to be secreted (exception: prostaglandin G/H synthase); the domain includes six cysteine residues which have been shown to be involved in disulfide bonds; the main structure is a two-stranded beta-sheet followed by a loop to a C-terminal short two-stranded sheet; Subdomains between the conserved cysteines vary in length; the region between the 5th and 6th cysteine contains two conserved glycines of which at least one is present in most EGF-like domains; a subset of these bind calcium.
Pssm-ID: 238010 Cd Length: 36 Bit Score: 36.69 E-value: 7.05e-03
10 20 30
....*....|....*....|....*....|
gi 665390891 1164 NGCSRHGQCTLENGEYRCDCIEGWAG-RDC 1192
Cdd:cd00053 6 NPCSNGGTCVNTPGSYRCVCPPGYTGdRSC 35
|
|
| YvrE |
COG3386 |
Sugar lactone lactonase YvrE [Carbohydrate transport and metabolism]; Sugar lactone lactonase ... |
1640-1919 |
7.27e-03 |
|
Sugar lactone lactonase YvrE [Carbohydrate transport and metabolism]; Sugar lactone lactonase YvrE is part of the Pathway/BioSystem: Non-phosphorylated Entner-Doudoroff pathway
Pssm-ID: 442613 [Multi-domain] Cd Length: 266 Bit Score: 41.42 E-value: 7.27e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 665390891 1640 PDGSLYVGDF--NLVRRITPDGKVYTILQLSATQVSYqyyLAVSPaDGHLYISDPERhqilRLVRLEKvkdpsinsdpvv 1717
Cdd:COG3386 17 PDGRLYWVDIpgGRIHRYDPDGGAVEVFAEPSGRPNG---LAFDP-DGRLLVADHGR----GLVRFDP------------ 76
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 665390891 1718 gsgqrcipgdegncGDGGPALLA-----RLSHPKGLAIAADRTMYIAD------GTNIRAVDPKGVIHTLIGHhghhnhw 1786
Cdd:COG3386 77 --------------ADGEVTVLAdeygkPLNRPNDGVVDPDGRLYFTDmgeylpTGALYRVDPDGSLRVLADG------- 135
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 665390891 1787 spapcsgtlmanqaqLQWPTGLALSPlDGS-LHFID--DRLVLRLTSDMKIRVVAGTPLHcsnggqDGRVNKTGADNvlg 1863
Cdd:COG3386 136 ---------------LTFPNGIAFSP-DGRtLYVADtgAGRIYRFDLDADGTLGNRRVFA------DLPDGPGGPDG--- 190
|
250 260 270 280 290
....*....|....*....|....*....|....*....|....*....|....*.
gi 665390891 1864 tvlaMAFSPFGNLYIADSDSRRVnsiRVVDTAGNMRyfaGKQEGTGSQTCDCAIGG 1919
Cdd:COG3386 191 ----LAVDADGNLWVALWGGGGV---VRFDPDGELL---GRIELPERRPTNVAFGG 236
|
|
| NHL-2_like |
cd14951 |
NHL repeat domain of NHL repeat-containing protein 2 and similar proteins; NHL ... |
1636-1770 |
8.05e-03 |
|
NHL repeat domain of NHL repeat-containing protein 2 and similar proteins; NHL repeat-containing protein 2 (NHLRC2) and related bacterial proteins; members of this eukaryotic and bacterial family are uncharacterized, the NHL repeat domain is found C-terminally of a thioredoxin domain. The NHL (NCL-1, HT2A and LIN-41) repeat is found in multiple tandem copies, typically as 6 instances. It is about 40 residues long and resembles the WD repeat and other beta-propeller structures.
Pssm-ID: 271321 [Multi-domain] Cd Length: 334 Bit Score: 41.41 E-value: 8.05e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 665390891 1636 LATGPDGSLYVGD--FNLVRRITP-DGKVYTILQLS---------------ATQVSYQYYLAVSPA-DGHLYISDPERHQ 1696
Cdd:cd14951 139 LSLAGWGELFVADseSSAIRAVSLkDGGVKTLVGGTrvgtglfdfgdrdgpGAEALLQHPLGVAALpDGSVYVADTYNHK 218
|
90 100 110 120 130 140 150
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 665390891 1697 ILRLvrlekvkdpsinsDPVVGSGQRCIPGDEGNCGDggpaLLARLSHPKGLAIAADRTMYIADgTN---IRAVDPK 1770
Cdd:cd14951 219 IKRV-------------DPATGEVSTLAGTGKAGYKD----LEAQFSEPSGLVVDGDGRLYVAD-TNnhrIRRLDLP 277
|
|
| |
