|
Name |
Accession |
Description |
Interval |
E-value |
| KASH |
pfam10541 |
Nuclear envelope localization domain; The KASH (for Klarsicht/ANC-1/Syne-1 homology) or KLS ... |
13484-13540 |
3.26e-25 |
|
Nuclear envelope localization domain; The KASH (for Klarsicht/ANC-1/Syne-1 homology) or KLS domain is a highly hydrophobic nuclear envelope localization domain of approximately 60 amino acids comprising a 20-amino-acid transmembrane region and a 30-35-residue C-terminal region that lies between the inner and the outer nuclear membranes. During meiotic prophase, telomeres cluster to form a bouquet arrangement of chromosomes. SUN and KASH domain proteins form complexes that span both membranes of the nuclear envelope. The KASH domain links the dynein motor complex of the microtubules, through the outer nuclear membrane to the Sad1 domain in the inner nuclear membrane which then interacts with the bouquet proteins Bqt1 and Bqt2 that are complexed with Bqt4, Rap1 and Taz1 and attached to the telomere. SUN domain-containing proteins are essential for recruiting KASH domain proteins at the outer nuclear membrane, and KASH domains provide a generic NE tethering device for functionally distinct proteins whose cytoplasmic domains mediate nuclear positioning, maintain physical connections with other cellular organelles, and possibly even influence chromosome dynamics.
Pssm-ID: 463142 Cd Length: 58 Bit Score: 102.29 E-value: 3.26e-25
10 20 30 40 50
....*....|....*....|....*....|....*....|....*....|....*...
gi 320544544 13484 FLGRVARASLPIQALMLLLLGVATLVPHG-EDYTCMFSNTFARSLEPMLSYPHGPPPT 13540
Cdd:pfam10541 1 FLGRVLRAALPLQLLLLLLLLLACLLPAGeEDYSCTLANNFARSFHPMLRYVNGPPPT 58
|
|
| SPEC |
cd00176 |
Spectrin repeats, found in several proteins involved in cytoskeletal structure; family members ... |
13196-13374 |
6.61e-15 |
|
Spectrin repeats, found in several proteins involved in cytoskeletal structure; family members include spectrin, alpha-actinin and dystrophin; the spectrin repeat forms a three helix bundle with the second helix interrupted by proline in some sequences; the repeats are independent folding units; tandem repeats are found in differing numbers and arrange in an antiparallel manner to form dimers; the repeats are defined by a characteristic tryptophan (W) residue in helix A and a leucine (L) at the carboxyl end of helix C and separated by a linker of 5 residues; two copies of the repeat are present here
Pssm-ID: 238103 [Multi-domain] Cd Length: 213 Bit Score: 78.26 E-value: 6.61e-15
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 320544544 13196 WQQIDNDLWRLEQWLQfaESTQKAQSA-PPSNIELLEDVTQDHREFLLDLESHKSIISSLNVVGDHLAThtLDTEKARQL 13274
Cdd:cd00176 2 LQQFLRDADELEAWLS--EKEELLSSTdYGDDLESVEALLKKHEALEAELAAHEERVEALNELGEQLIE--EGHPDAEEI 77
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 320544544 13275 RSRLEADNERWNNVCINATKWQGLLQTALMGNSEFHQTIgELVEWLQRTEQNIKASEPVDLTEErsvLETKFKKFKDLRA 13354
Cdd:cd00176 78 QERLEELNQRWEELRELAEERRQRLEEALDLQQFFRDAD-DLEQWLEEKEAALASEDLGKDLES---VEELLKKHKELEE 153
|
170 180
....*....|....*....|
gi 320544544 13355 ELERCEPRVVSLQDAADQLL 13374
Cdd:cd00176 154 ELEAHEPRLKSLNELAEELL 173
|
|
| SMC_prok_B |
TIGR02168 |
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ... |
12205-12954 |
2.28e-14 |
|
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]
Pssm-ID: 274008 [Multi-domain] Cd Length: 1179 Bit Score: 82.41 E-value: 2.28e-14
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 320544544 12205 KESEEQLAALRAHLQTLartEEQLRQLKERHQNSEvapsvassdddgilEVLALWQKIFQDTFQEYHRLSTRLARSQNSs 12284
Cdd:TIGR02168 249 KEAEEELEELTAELQEL---EEKLEELRLEVSELE--------------EEIEELQKELYALANEISRLEQQKQILRER- 310
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 320544544 12285 ealrlwRQYLQHVQSFLSCAIPEDYSSLREQQQLCAihqnllisqqsvlsetplesELSEQYKALTNLHNETLSRIMQRN 12364
Cdd:TIGR02168 311 ------LANLERQLEELEAQLEELESKLDELAEELA--------------------ELEEKLEELKEELESLEAELEELE 364
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 320544544 12365 GELERRVSGWNAYRQQL----AALLDWLRQREAERNALQLRYIHLKRVPHLKHRLDAMIQQLDQgEQQSKALQEQQQELA 12440
Cdd:TIGR02168 365 AELEELESRLEELEEQLetlrSKVAQLELQIASLNNEIERLEARLERLEDRRERLQQEIEELLK-KLEEAELKELQAELE 443
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 320544544 12441 RH---CDDALATAMRMEQA--SIGQRISNLRAALKTWQGFLQRVTQLSESYEQRVNQLQQEFGAAQKLLDAN-------- 12507
Cdd:TIGR02168 444 ELeeeLEELQEELERLEEAleELREELEEAEQALDAAERELAQLQARLDSLERLQENLEGFSEGVKALLKNQsglsgilg 523
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 320544544 12508 --SESLPTQP---AAIEQLLGSlRAQRV---QLGAQVSALESLT------VTQEELKecISPHDMKTIRQRNWLLWQQ-- 12571
Cdd:TIGR02168 524 vlSELISVDEgyeAAIEAALGG-RLQAVvveNLNAAKKAIAFLKqnelgrVTFLPLD--SIKGTEIQGNDREILKNIEgf 600
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 320544544 12572 --------------HADLDYQLANLI--NSIEERLSLLSNYQIRY-------DRIS-----------QWLQRLEQRVEKD 12617
Cdd:TIGR02168 601 lgvakdlvkfdpklRKALSYLLGGVLvvDDLDNALELAKKLRPGYrivtldgDLVRpggvitggsakTNSSILERRREIE 680
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 320544544 12618 ADVTAMTNPEQAAKQLEQQVN---SELQLRDKEREWLLSTSRELLTLYSEPEVR-SQVQQQSDSLIDRWQRLKYLAKQKA 12693
Cdd:TIGR02168 681 ELEEKIEELEEKIAELEKALAelrKELEELEEELEQLRKELEELSRQISALRKDlARLEAEVEQLEERIAQLSKELTELE 760
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 320544544 12694 TKIGELKMTLLRLEERIALIRAWLFEVESQLDkplNFESYTPNVIEAKLKEHEQIQRsiehHSSNVGEVLNLVEMLLNDA 12773
Cdd:TIGR02168 761 AEIEELEERLEEAEEELAEAEAEIEELEAQIE---QLKEELKALREALDELRAELTL----LNEEAANLRERLESLERRI 833
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 320544544 12774 DSWRTQvntsglaasAQNLEQRWKNVCSQSAERKARILTIWNLLQQLIKLTAEHKNWLGKQESQI--AGFERDQKSHSKH 12851
Cdd:TIGR02168 834 AATERR---------LEDLEEQIEELSEDIESLAAEIEELEELIEELESELEALLNERASLEEALalLRSELEELSEELR 904
|
730 740 750 760 770 780 790 800
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 320544544 12852 KLEERQMELRAKLEELESQ--SVNLR------QLEQIYAKLAMSAGVEPENIQKLTLPTKVMVSMWR----QLTPRCHAL 12919
Cdd:TIGR02168 905 ELESKRSELRRELEELREKlaQLELRleglevRIDNLQERLSEEYSLTLEEAEALENKIEDDEEEARrrlkRLENKIKEL 984
|
810 820 830 840
....*....|....*....|....*....|....*....|..
gi 320544544 12920 ----LDAID--KDAKLMREFNNAQLE-ATNSLNAIQKALEQL 12954
Cdd:TIGR02168 985 gpvnLAAIEeyEELKERYDFLTAQKEdLTEAKETLEEAIEEI 1026
|
|
| mukB |
PRK04863 |
chromosome partition protein MukB; |
12163-13113 |
4.12e-14 |
|
chromosome partition protein MukB;
Pssm-ID: 235316 [Multi-domain] Cd Length: 1486 Bit Score: 81.54 E-value: 4.12e-14
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 320544544 12163 TLANVAETQdKERKELDKEVTLAKAYFNNvqqDISREAPQNPKESEEQLAALRAhlqtLARTEEQLRQLKERHQN--SEV 12240
Cdd:PRK04863 245 TLEAIRVTQ-SDRDLFKHLITESTNYVAA---DYMRHANERRVHLEEALELRRE----LYTSRRQLAAEQYRLVEmaREL 316
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 320544544 12241 ApsvASSDDDGILEvlalwqkifqdtfQEYHRLSTRLARSQNsseALRLWRQYLQHVQSFLscaipEDYSSLREQQQLCA 12320
Cdd:PRK04863 317 A---ELNEAESDLE-------------QDYQAASDHLNLVQT---ALRQQEKIERYQADLE-----ELEERLEEQNEVVE 372
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 320544544 12321 IHQNLLISQQSVLSETPLE-SELSEQykaltnlhnetLSRIMQRNGELERRVSgwnAYRQQLAAL--------------- 12384
Cdd:PRK04863 373 EADEQQEENEARAEAAEEEvDELKSQ-----------LADYQQALDVQQTRAI---QYQQAVQALerakqlcglpdltad 438
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 320544544 12385 --LDWLRQREAERNALQLRyihlkrVPHLKHRL---DAMIQQLDQGEQQSKAL-----QEQQQELARhcdDALATAMrmE 12454
Cdd:PRK04863 439 naEDWLEEFQAKEQEATEE------LLSLEQKLsvaQAAHSQFEQAYQLVRKIagevsRSEAWDVAR---ELLRRLR--E 507
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 320544544 12455 QASIGQRISNLRAALKTWQGFL---QRVTQLSESYEQRVNQ---LQQEFGAAQKLLDANSESLPTQPAAIEQLLGSLRAQ 12528
Cdd:PRK04863 508 QRHLAEQLQQLRMRLSELEQRLrqqQRAERLLAEFCKRLGKnldDEDELEQLQEELEARLESLSESVSEARERRMALRQQ 587
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 320544544 12529 RVQLGAQVSALESLT----VTQ---EELKECiSPHDMKTiRQRNWLLWQQHADLDYQLANLINSIEERLSLLsnyQIRYD 12601
Cdd:PRK04863 588 LEQLQARIQRLAARApawlAAQdalARLREQ-SGEEFED-SQDVTEYMQQLLERERELTVERDELAARKQAL---DEEIE 662
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 320544544 12602 RISQ-------WLQRLEQRV------EKDADVTAMTNPEQAAkqLEQQVNSELQLRDkerewLLSTSRELLTLYSEPEVR 12668
Cdd:PRK04863 663 RLSQpggsedpRLNALAERFggvllsEIYDDVSLEDAPYFSA--LYGPARHAIVVPD-----LSDAAEQLAGLEDCPEDL 735
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 320544544 12669 SQVQQQSDSLIDRWQRLKYLAKQKATKIGELKMTLLRL-----------EERIALIRAWLFEVESQLDKpLNFESytpnv 12737
Cdd:PRK04863 736 YLIEGDPDSFDDSVFSVEELEKAVVVKIADRQWRYSRFpevplfgraarEKRIEQLRAEREELAERYAT-LSFDV----- 809
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 320544544 12738 ieaklkehEQIQRSIEHHSSNVGEVLNLV-----EMLLNDADSWRTQVNTSGLAASAQNLEQRwknvcsqSAERKARilt 12812
Cdd:PRK04863 810 --------QKLQRLHQAFSRFIGSHLAVAfeadpEAELRQLNRRRVELERALADHESQEQQQR-------SQLEQAK--- 871
|
730 740 750 760 770 780 790 800
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 320544544 12813 iwNLLQQLIKLtaehknwlgkqESQIAGFERDQkshskhkLEERQMELRAKLEELE-------SQSVNLRQLEQIYAKLA 12885
Cdd:PRK04863 872 --EGLSALNRL-----------LPRLNLLADET-------LADRVEEIREQLDEAEeakrfvqQHGNALAQLEPIVSVLQ 931
|
810 820 830 840 850 860 870 880
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 320544544 12886 msagVEPENIQKLTLPTKVMVSMWRQLTPRCHALLDAIDKDAKLMREFNNAQLEATNSLNaiqkalEQLPsaenqqtska 12965
Cdd:PRK04863 932 ----SDPEQFEQLKQDYQQAQQTQRDAKQQAFALTEVVQRRAHFSYEDAAEMLAKNSDLN------EKLR---------- 991
|
890 900 910 920 930 940 950 960
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 320544544 12966 epkavlQRLESLEKKLQDAQQHVQQADNLAQEAKTRtkqqpqlkqLLELVSAYTTLWQTVQtrivtlkttwltRAAQAAA 13045
Cdd:PRK04863 992 ------QRLEQAEQERTRAREQLRQAQAQLAQYNQV---------LASLKSSYDAKRQMLQ------------ELKQELQ 1044
|
970 980 990 1000 1010 1020 1030
....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 320544544 13046 SLPV----SEAANAAVQVNTLSQRkLRQAQQmQREtsitakdayimELQTAITECQNNLDELQRTVVDKTRK 13113
Cdd:PRK04863 1045 DLGVpadsGAEERARARRDELHAR-LSANRS-RRN-----------QLEKQLTFCEAEMDNLTKKLRKLERD 1103
|
|
| COG4913 |
COG4913 |
Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown]; |
12265-12876 |
1.13e-13 |
|
Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];
Pssm-ID: 443941 [Multi-domain] Cd Length: 1089 Bit Score: 79.96 E-value: 1.13e-13
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 320544544 12265 DTFQEYH-RLSTRLARSqnSSEALRLWRQylqhVQSFlscaipEDYSSLREqqqlcaihqnlLISQQsVLSETPLES--- 12340
Cdd:COG4913 173 DSFSAYLaRLRRRLGIG--SEKALRLLHK----TQSF------KPIGDLDD-----------FVREY-MLEEPDTFEaad 228
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 320544544 12341 ELSEQYKALTNLHN---------ETLSRIMQRNGELERRVSGWNAYRQQLAALLDWLRQREAERnalqlryihlkrvphL 12411
Cdd:COG4913 229 ALVEHFDDLERAHEaledareqiELLEPIRELAERYAAARERLAELEYLRAALRLWFAQRRLEL---------------L 293
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 320544544 12412 KHRLDAMIQQLDQGEQQSKALQEQQQELARHCDDALAtamRMEQASiGQRISNLRAALKTWQGFLQRVTQLSESYEQRVN 12491
Cdd:COG4913 294 EAELEELRAELARLEAELERLEARLDALREELDELEA---QIRGNG-GDRLEQLEREIERLERELEERERRRARLEALLA 369
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 320544544 12492 QL-------QQEFGAAQKLLDANSESLPTQPAAIEQLLGSLRAQRVQLGAQVSALESltvTQEELKECIS--PHDMKTIR 12562
Cdd:COG4913 370 ALglplpasAEEFAALRAEAAALLEALEEELEALEEALAEAEAALRDLRRELRELEA---EIASLERRKSniPARLLALR 446
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 320544544 12563 QRnwllWQQH-----ADLDYqLANLI----------NSIE-----ERLSLLSNYQiRYDRISQWLQRLE-------QRVE 12615
Cdd:COG4913 447 DA----LAEAlgldeAELPF-VGELIevrpeeerwrGAIErvlggFALTLLVPPE-HYAAALRWVNRLHlrgrlvyERVR 520
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 320544544 12616 KDADVTAMTNPEQ---AAK--------------QLEQQ-----VNSELQLRDKERewllSTSRELLTlySEPEVRSQVQQ 12673
Cdd:COG4913 521 TGLPDPERPRLDPdslAGKldfkphpfrawleaELGRRfdyvcVDSPEELRRHPR----AITRAGQV--KGNGTRHEKDD 594
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 320544544 12674 QSDsLIDRW-------QRLKYLAKQkatkIGELKMTLLRLEERIALIRAWLFEVESQLDKPLNFESYTPNVIEAK--LKE 12744
Cdd:COG4913 595 RRR-IRSRYvlgfdnrAKLAALEAE----LAELEEELAEAEERLEALEAELDALQERREALQRLAEYSWDEIDVAsaERE 669
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 320544544 12745 HEQIQRSIEHHSSNVGEVLNLVEMLlndaDSWRTQVNTS-----GLAASAQNLEQRWKNvCSQSAERKARIltiwnlLQQ 12819
Cdd:COG4913 670 IAELEAELERLDASSDDLAALEEQL----EELEAELEELeeeldELKGEIGRLEKELEQ-AEEELDELQDR------LEA 738
|
650 660 670 680 690
....*....|....*....|....*....|....*....|....*....|....*..
gi 320544544 12820 LIKLTAEHKNWLGKQESQIAGFERDQKSHSKHkLEERQMELRAKLEELESQSVNLRQ 12876
Cdd:COG4913 739 AEDLARLELRALLEERFAAALGDAVERELREN-LEERIDALRARLNRAEEELERAMR 794
|
|
| SPEC |
cd00176 |
Spectrin repeats, found in several proteins involved in cytoskeletal structure; family members ... |
12703-12923 |
2.04e-09 |
|
Spectrin repeats, found in several proteins involved in cytoskeletal structure; family members include spectrin, alpha-actinin and dystrophin; the spectrin repeat forms a three helix bundle with the second helix interrupted by proline in some sequences; the repeats are independent folding units; tandem repeats are found in differing numbers and arrange in an antiparallel manner to form dimers; the repeats are defined by a characteristic tryptophan (W) residue in helix A and a leucine (L) at the carboxyl end of helix C and separated by a linker of 5 residues; two copies of the repeat are present here
Pssm-ID: 238103 [Multi-domain] Cd Length: 213 Bit Score: 62.08 E-value: 2.04e-09
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 320544544 12703 LLRLEERIALIRAWLFEVESQLDKPLNfeSYTPNVIEAKLKEHEQIQRSIEHHSSNVGEVLNLVEMLLNDAdswrtQVNT 12782
Cdd:cd00176 2 LQQFLRDADELEAWLSEKEELLSSTDY--GDDLESVEALLKKHEALEAELAAHEERVEALNELGEQLIEEG-----HPDA 74
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 320544544 12783 SGLAASAQNLEQRWKNVCSQSAERKARILTIWNLLQQLIKLTAEhKNWLGKQESQIAgfeRDQKSHSKHKLEERQMELRA 12862
Cdd:cd00176 75 EEIQERLEELNQRWEELRELAEERRQRLEEALDLQQFFRDADDL-EQWLEEKEAALA---SEDLGKDLESVEELLKKHKE 150
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 320544544 12863 KLEELESQSVNLRQLEQIYAKLAMSAgvEPENIQKLTLPTKVMVSMWRQL----TPRCHALLDAI 12923
Cdd:cd00176 151 LEEELEAHEPRLKSLNELAEELLEEG--HPDADEEIEEKLEELNERWEELlelaEERQKKLEEAL 213
|
|
| SPEC |
cd00176 |
Spectrin repeats, found in several proteins involved in cytoskeletal structure; family members ... |
17-220 |
5.12e-09 |
|
Spectrin repeats, found in several proteins involved in cytoskeletal structure; family members include spectrin, alpha-actinin and dystrophin; the spectrin repeat forms a three helix bundle with the second helix interrupted by proline in some sequences; the repeats are independent folding units; tandem repeats are found in differing numbers and arrange in an antiparallel manner to form dimers; the repeats are defined by a characteristic tryptophan (W) residue in helix A and a leucine (L) at the carboxyl end of helix C and separated by a linker of 5 residues; two copies of the repeat are present here
Pssm-ID: 238103 [Multi-domain] Cd Length: 213 Bit Score: 60.92 E-value: 5.12e-09
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 320544544 17 EYVDGVDEVQRWLLQAEVQVQERSL--TPTQMKELLQR---INHEITAIYERFTLVKTNGQLIIEncRNSEEKTLVQTTI 91
Cdd:cd00176 4 QFLRDADELEAWLSEKEELLSSTDYgdDLESVEALLKKheaLEAELAAHEERVEALNELGEQLIE--EGHPDAEEIQERL 81
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 320544544 92 DQLAASLAQVRGWLDEKKQAVGDSLDAWtRFMNLYQIVMSWASEKRNFIDQTIELRTLPEARNKLN---DYVTSVKSIKP 168
Cdd:cd00176 82 EELNQRWEELRELAEERRQRLEEALDLQ-QFFRDADDLEQWLEEKEAALASEDLGKDLESVEELLKkhkELEEELEAHEP 160
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|..
gi 320544544 169 IVKHLSEMDKELEHIGQVTTVGDLKDKLQEAEDAKISVEAVLLERNSLLQEA 220
Cdd:cd00176 161 RLKSLNELAEELLEEGHPDADEEIEEKLEELNERWEELLELAEERQKKLEEA 212
|
|
| DUF3584 |
pfam12128 |
Protein of unknown function (DUF3584); This protein is found in bacteria and eukaryotes. ... |
11995-12664 |
2.28e-08 |
|
Protein of unknown function (DUF3584); This protein is found in bacteria and eukaryotes. Proteins in this family are typically between 943 to 1234 amino acids in length. This family contains a P-loop motif suggesting it is a nucleotide binding protein. It may be involved in replication.
Pssm-ID: 432349 [Multi-domain] Cd Length: 1191 Bit Score: 62.55 E-value: 2.28e-08
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 320544544 11995 YERLRKATERLEGLAGDLHNREQLIDELKGAAKPLIEScDVQIVEQIEsAVQEAVVAWNdtsenlQQLRTryqraveLWD 12074
Cdd:pfam12128 233 IAGIMKIRPEFTKLQQEFNTLESAELRLSHLHFGYKSD-ETLIASRQE-ERQETSAELN------QLLRT-------LDD 297
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 320544544 12075 KYRNASAAVKNSIDQQMDAVKSLEQPLDAL--QHAKVCQDNLTTqndrilelrdivakIAADvgLDASALMQGELDALGQ 12152
Cdd:pfam12128 298 QWKEKRDELNGELSAADAAVAKDRSELEALedQHGAFLDADIET--------------AAAD--QEQLPSWQSELENLEE 361
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 320544544 12153 RLaeckDAITTLANVAETQDKERKELDKEVTLAKAYFNNVQQDISREApqnpkeSEEQLAALRAHLQTL-----ARTEEQ 12227
Cdd:pfam12128 362 RL----KALTGKHQDVTAKYNRRRSKIKEQNNRDIAGIKDKLAKIREA------RDRQLAVAEDDLQALeselrEQLEAG 431
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 320544544 12228 LRQLKERHQNSEVAPSVASS--DDDGILEVLALWQKIFQD-----------TFQEYHRLSTRLA----RSQNSSEALRLW 12290
Cdd:pfam12128 432 KLEFNEEEYRLKSRLGELKLrlNQATATPELLLQLENFDErierareeqeaANAEVERLQSELRqarkRRDQASEALRQA 511
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 320544544 12291 RQYLQHVQSFLSCA----IPEDYS---SLREQQQLCAIHQNLLISQQsVLSETPLESELSE-QYKALTNLHNETLsrimq 12362
Cdd:pfam12128 512 SRRLEERQSALDELelqlFPQAGTllhFLRKEAPDWEQSIGKVISPE-LLHRTDLDPEVWDgSVGGELNLYGVKL----- 585
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 320544544 12363 rngELER-RVSGWNAYRQQLAALLDWL---------RQREAERNALQLRyihlKRVPHLKHRLDAMIQQLDQGEQQSKAL 12432
Cdd:pfam12128 586 ---DLKRiDVPEWAASEEELRERLDKAeealqsareKQAAAEEQLVQAN----GELEKASREETFARTALKNARLDLRRL 658
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 320544544 12433 QEQQQELARHCDDALATAMRMEQASIGQRISNLRAALKTWQGFLQRVT-QLSESYEQRVNQLQQEFGAAQklldansesl 12511
Cdd:pfam12128 659 FDEKQSEKDKKNKALAERKDSANERLNSLEAQLKQLDKKHQAWLEEQKeQKREARTEKQAYWQVVEGALD---------- 728
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 320544544 12512 ptqpAAIEQLLGSLRAQRVQLGAQVSALesltvtQEELKECISPHDMKTIRQrnwllwqqhADLDYQLANLINSIEerls 12591
Cdd:pfam12128 729 ----AQLALLKAAIAARRSGAKAELKAL------ETWYKRDLASLGVDPDVI---------AKLKREIRTLERKIE---- 785
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 320544544 12592 llsnyQIRYDR--ISQWLQRLEQR--VEKDADVTAMTNPEQAAKQLEQQV---NSELQLRDKEREWLLSTSRELLTLYSE 12664
Cdd:pfam12128 786 -----RIAVRRqeVLRYFDWYQETwlQRRPRLATQLSNIERAISELQQQLarlIADTKLRRAKLEMERKASEKQQVRLSE 860
|
|
| YhaN |
COG4717 |
Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown]; |
11930-12426 |
9.69e-08 |
|
Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown];
Pssm-ID: 443752 [Multi-domain] Cd Length: 641 Bit Score: 60.17 E-value: 9.69e-08
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 320544544 11930 KLERDISQLQDDHAFLESKcTNIMAILRSRLAVWLRYERQLElvhgsvQETDFMMELIRVHGqvDYERLRKATERLEGLA 12009
Cdd:COG4717 75 ELEEELKEAEEKEEEYAEL-QEELEELEEELEELEAELEELR------EELEKLEKLLQLLP--LYQELEALEAELAELP 145
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 320544544 12010 GDLHNREQLIDELKGAAKpLIESCDVQIVEQIESAVQEAVVAWNDTSENLQQLRTRYQRAVELWDKYRNASAAVKNSIDQ 12089
Cdd:COG4717 146 ERLEELEERLEELRELEE-ELEELEAELAELQEELEELLEQLSLATEEELQDLAEELEELQQRLAELEEELEEAQEELEE 224
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 320544544 12090 QMDAVKSLEQPLDALQHAKVcqdnlTTQNDRILELRDIVAKIAA-DVGLDASALMQGELDALGQRLAECKDAITTLANVA 12168
Cdd:COG4717 225 LEEELEQLENELEAAALEER-----LKEARLLLLIAAALLALLGlGGSLLSLILTIAGVLFLVLGLLALLFLLLAREKAS 299
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 320544544 12169 ETQDKER-KELDKEVTLAKAYFNNVQQDISREAPQNPKESEE---QLAALRAHLQTLARTEEQLRQLKERHQNSEVAPSV 12244
Cdd:COG4717 300 LGKEAEElQALPALEELEEEELEELLAALGLPPDLSPEELLElldRIEELQELLREAEELEEELQLEELEQEIAALLAEA 379
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 320544544 12245 ASSDDDGILEVLALWQKiFQDTFQEYHRLSTRLARSQNSSEALRLWRQYLQhvqsflscaIPEDYSSLREQQQLcaihqn 12324
Cdd:COG4717 380 GVEDEEELRAALEQAEE-YQELKEELEELEEQLEELLGELEELLEALDEEE---------LEEELEELEEELEE------ 443
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 320544544 12325 llisqqsvlsetpLESELSEQYKALTNLHNETlsRIMQRNGELERRvsgwnayRQQLAALLDWLRQREAERNALQL---- 12400
Cdd:COG4717 444 -------------LEEELEELREELAELEAEL--EQLEEDGELAEL-------LQELEELKAELRELAEEWAALKLalel 501
|
490 500 510
....*....|....*....|....*....|.
gi 320544544 12401 -----RYIHLKRVPHLKHRLDAMIQQLDQGE 12426
Cdd:COG4717 502 leearEEYREERLPPVLERASEYFSRLTDGR 532
|
|
| SMC_prok_B |
TIGR02168 |
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ... |
12627-13397 |
6.23e-07 |
|
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]
Pssm-ID: 274008 [Multi-domain] Cd Length: 1179 Bit Score: 57.76 E-value: 6.23e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 320544544 12627 EQAAKQLEQQVNS-ELQ---------LRDKEREWLLStsreLLTLysepevrsqvqqQSDSLIDRWQRLKYLAKQKATKI 12696
Cdd:TIGR02168 192 EDILNELERQLKSlERQaekaerykeLKAELRELELA----LLVL------------RLEELREELEELQEELKEAEEEL 255
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 320544544 12697 GELKMTLLRLEERIALIRAWLFEVESQLDKpLNFESYTPNVIEAKLKEHEQIQRSIEHHSSNVGEVLNLVemlLNDADSW 12776
Cdd:TIGR02168 256 EELTAELQELEEKLEELRLEVSELEEEIEE-LQKELYALANEISRLEQQKQILRERLANLERQLEELEAQ---LEELESK 331
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 320544544 12777 RTQVNTSgLAASAQNLEQRWKNVCSQSAERKARILTIWNLLQQLIKLTAEhknwLGKQESQIAGFERDQKSHSKhkleeR 12856
Cdd:TIGR02168 332 LDELAEE-LAELEEKLEELKEELESLEAELEELEAELEELESRLEELEEQ----LETLRSKVAQLELQIASLNN-----E 401
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 320544544 12857 QMELRAKLEELESqsvNLRQLEQIYAKLAMsagvEPENIQKLTLPTKVmvsmwrqltprchALLDAIDKDAKLMREFNNA 12936
Cdd:TIGR02168 402 IERLEARLERLED---RRERLQQEIEELLK----KLEEAELKELQAEL-------------EELEEELEELQEELERLEE 461
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 320544544 12937 QLEatnslnAIQKALEQLPSAenQQTSKAEPKAVLQRLESLEKKLQDAQQHVQQADNLAQEAKTRTKQQPQLKQLLELVS 13016
Cdd:TIGR02168 462 ALE------ELREELEEAEQA--LDAAERELAQLQARLDSLERLQENLEGFSEGVKALLKNQSGLSGILGVLSELISVDE 533
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 320544544 13017 AY-----TTLWQTVQTRIV-TLKTTWLTRAAQA------AASLPVSEAANAAVQVNTLSQRKLRQAQQMQRETSITAKDA 13084
Cdd:TIGR02168 534 GYeaaieAALGGRLQAVVVeNLNAAKKAIAFLKqnelgrVTFLPLDSIKGTEIQGNDREILKNIEGFLGVAKDLVKFDPK 613
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 320544544 13085 Y-------------IMELQTAItECQNNLDELQRTVVDK----------TRKPGpQKIAKLLGNAQSSTELVKHLSHLLL 13141
Cdd:TIGR02168 614 LrkalsyllggvlvVDDLDNAL-ELAKKLRPGYRIVTLDgdlvrpggviTGGSA-KTNSSILERRREIEELEEKIEELEE 691
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 320544544 13142 TECKADDQAAEVDT-VAELTLRFDTLQSQW--KARQQHDQNAS-EVGRLTCPLCTQRNWQQIDNDLWRLEQWLQFAESTQ 13217
Cdd:TIGR02168 692 KIAELEKALAELRKeLEELEEELEQLRKELeeLSRQISALRKDlARLEAEVEQLEERIAQLSKELTELEAEIEELEERLE 771
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 320544544 13218 KAQSAPPSNIELLEDVTQDHREFLLDLESHKSIISSLNvvgdhlATHTLDTEKARQLRSRLEADNERwnnvcINATKwqg 13297
Cdd:TIGR02168 772 EAEEELAEAEAEIEELEAQIEQLKEELKALREALDELR------AELTLLNEEAANLRERLESLERR-----IAATE--- 837
|
730 740 750 760 770 780 790 800
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 320544544 13298 llqtalmgnsefhQTIGELVEWLQRTEQNIKASEPV--DLTEERSVLETKFKKFKDLRAELERCEPRVVSLQDAADQLLR 13375
Cdd:TIGR02168 838 -------------RRLEDLEEQIEELSEDIESLAAEieELEELIEELESELEALLNERASLEEALALLRSELEELSEELR 904
|
810 820
....*....|....*....|..
gi 320544544 13376 SVEGSEQQSQHTYERTLSRLTD 13397
Cdd:TIGR02168 905 ELESKRSELRRELEELREKLAQ 926
|
|
| sbcc |
TIGR00618 |
exonuclease SbcC; All proteins in this family for which functions are known are part of an ... |
11815-12439 |
8.06e-07 |
|
exonuclease SbcC; All proteins in this family for which functions are known are part of an exonuclease complex with sbcD homologs. This complex is involved in the initiation of recombination to regulate the levels of palindromic sequences in DNA. This family is based on the phylogenomic analysis of JA Eisen (1999, Ph.D. Thesis, Stanford University). [DNA metabolism, DNA replication, recombination, and repair]
Pssm-ID: 129705 [Multi-domain] Cd Length: 1042 Bit Score: 57.29 E-value: 8.06e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 320544544 11815 QEPAIEPEKVGELFSLSHKISTQIAEELEGASVLRDQLQAIQEgisnQRKHQAKISVILDECEAAERQGADVLE------ 11888
Cdd:TIGR00618 212 CMPDTYHERKQVLEKELKHLREALQQTQQSHAYLTQKREAQEE----QLKKQQLLKQLRARIEELRAQEAVLEEtqerin 287
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 320544544 11889 ------------KAVADCQAAGEELVISWQEIMRIR-QMLHTLPMRLKMSVSPVKLERDISQLQDDHAFLE---SKCTNI 11952
Cdd:TIGR00618 288 rarkaaplaahiKAVTQIEQQAQRIHTELQSKMRSRaKLLMKRAAHVKQQSSIEEQRRLLQTLHSQEIHIRdahEVATSI 367
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 320544544 11953 MAI------LRSRLAVWLR-YERQLELVHGSVQETDfmmELIRVHGQVDYERLRKATERleglaGDL-HNREQLIDELKG 12024
Cdd:TIGR00618 368 REIscqqhtLTQHIHTLQQqKTTLTQKLQSLCKELD---ILQREQATIDTRTSAFRDLQ-----GQLaHAKKQQELQQRY 439
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 320544544 12025 AA-KPLIESCDVQIVEQIESAVQEAVVAWNDTSENLQQLRTRYQRAVELwdkyRNASAAVKNSI-DQQMDAVKSLEQPLD 12102
Cdd:TIGR00618 440 AElCAAAITCTAQCEKLEKIHLQESAQSLKEREQQLQTKEQIHLQETRK----KAVVLARLLELqEEPCPLCGSCIHPNP 515
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 320544544 12103 ALQHAkvcqDNLTTQNDRILELRDIVAKiaadvGLDASALMQGELDALGQRLAECKDAITTLanvaetqDKERKELDKEV 12182
Cdd:TIGR00618 516 ARQDI----DNPGPLTRRMQRGEQTYAQ-----LETSEEDVYHQLTSERKQRASLKEQMQEI-------QQSFSILTQCD 579
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 320544544 12183 TLAKAYFNNVQQDISREAPQNPKESEEQLaalrahlQTLARTEEQLRQLKERHQNSEVAPSVASSDDDGILEVLAL---- 12258
Cdd:TIGR00618 580 NRSKEDIPNLQNITVRLQDLTEKLSEAED-------MLACEQHALLRKLQPEQDLQDVRLHLQQCSQELALKLTALhalq 652
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 320544544 12259 -----------WQKIFQDTFQEYHRLSTRLARSQNSSEALRLWRQYLQHVQSFLSC--AIPEDYSSLREQQQLCAIHQNL 12325
Cdd:TIGR00618 653 ltltqervrehALSIRVLPKELLASRQLALQKMQSEKEQLTYWKEMLAQCQTLLREleTHIEEYDREFNEIENASSSLGS 732
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 320544544 12326 LISQQSVL---SETPLESELSEQYKALTNLH---NETLSRIMQRNGELERRVSGWNAYRQQLAALLDWLRQREAE----- 12394
Cdd:TIGR00618 733 DLAAREDAlnqSLKELMHQARTVLKARTEAHfnnNEEVTAALQTGAELSHLAAEIQFFNRLREEDTHLLKTLEAEigqei 812
|
650 660 670 680 690 700
....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 320544544 12395 ---------------------RNALQLRYIHLKRVPHLKHRLDAMIQQLDQGEQQSKALQEQQQEL 12439
Cdd:TIGR00618 813 psdedilnlqcetlvqeeeqfLSRLEEKSATLGEITHQLLKYEECSKQLAQLTQEQAKIIQLSDKL 878
|
|
| YhaN |
COG4717 |
Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown]; |
12817-13241 |
1.47e-05 |
|
Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown];
Pssm-ID: 443752 [Multi-domain] Cd Length: 641 Bit Score: 52.85 E-value: 1.47e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 320544544 12817 LQQLIKLTAEhknwLGKQESQIAGFERDQKShsKHKLEERQMELRAKLEELESQSVNLRQLEQIYAKLAMSAGVEPEniq 12896
Cdd:COG4717 70 LKELKELEEE----LKEAEEKEEEYAELQEE--LEELEEELEELEAELEELREELEKLEKLLQLLPLYQELEALEAE--- 140
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 320544544 12897 kltlptkvmvsmWRQLTPRCHALLDAIDKDAKLMREFNNAQLEATNSLNAIQKALEQLPSAENQ--QTSKAEPKAVLQRL 12974
Cdd:COG4717 141 ------------LAELPERLEELEERLEELRELEEELEELEAELAELQEELEELLEQLSLATEEelQDLAEELEELQQRL 208
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 320544544 12975 ESLEKKLQDAQQHVQQADN---LAQEAKTRTKQQPQLKQ----------LLELVSAYTTLWQTVQTR---------IVTL 13032
Cdd:COG4717 209 AELEEELEEAQEELEELEEeleQLENELEAAALEERLKEarlllliaaaLLALLGLGGSLLSLILTIagvlflvlgLLAL 288
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 320544544 13033 KTTWLTRAAQAAASLpvSEAANAAVQVNTLSQRKLRQAQQmQRETSITAKDAYIMELQTAITECQNNLDELQRTVVDKTR 13112
Cdd:COG4717 289 LFLLLAREKASLGKE--AEELQALPALEELEEEELEELLA-ALGLPPDLSPEELLELLDRIEELQELLREAEELEEELQL 365
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 320544544 13113 KPGPQKIAKLLGNAQSSTE------------------LVKHLSHLLLTECKADDQAAEVDTVAELTLRFDTLQSQWKA-R 13173
Cdd:COG4717 366 EELEQEIAALLAEAGVEDEeelraaleqaeeyqelkeELEELEEQLEELLGELEELLEALDEEELEEELEELEEELEElE 445
|
410 420 430 440 450 460 470
....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 320544544 13174 QQHDQNASEVGRLTcplctqrnwQQI-----DNDLWRLEQWLQFAESTQKAQSAPPSNIELLEDVTQDHREFL 13241
Cdd:COG4717 446 EELEELREELAELE---------AELeqleeDGELAELLQELEELKAELRELAEEWAALKLALELLEEAREEY 509
|
|
| SPEC |
cd00176 |
Spectrin repeats, found in several proteins involved in cytoskeletal structure; family members ... |
9546-9732 |
5.30e-05 |
|
Spectrin repeats, found in several proteins involved in cytoskeletal structure; family members include spectrin, alpha-actinin and dystrophin; the spectrin repeat forms a three helix bundle with the second helix interrupted by proline in some sequences; the repeats are independent folding units; tandem repeats are found in differing numbers and arrange in an antiparallel manner to form dimers; the repeats are defined by a characteristic tryptophan (W) residue in helix A and a leucine (L) at the carboxyl end of helix C and separated by a linker of 5 residues; two copies of the repeat are present here
Pssm-ID: 238103 [Multi-domain] Cd Length: 213 Bit Score: 48.98 E-value: 5.30e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 320544544 9546 QELDELLQSLSSVEDGIANMN----QSSLDGMLHGLKLIQSNLEVHERDAIELKNQAKKL-----PTDPATERLLNDTVD 9616
Cdd:cd00176 7 RDADELEAWLSEKEELLSSTDygddLESVEALLKKHEALEAELAAHEERVEALNELGEQLieeghPDAEEIQERLEELNQ 86
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 320544544 9617 RIDLLLRRTQQgitmIANAMHGQKKRQQeideYQQHLLELEQWIIEVSAELASfeptSDSSTDEQVLKSQVERSQQLLRT 9696
Cdd:cd00176 87 RWEELRELAEE----RRQRLEEALDLQQ----FFRDADDLEQWLEEKEAALAS----EDLGKDLESVEELLKKHKELEEE 154
|
170 180 190
....*....|....*....|....*....|....*...
gi 320544544 9697 LKDRQQSMEDLVEQTRQL--QSHPDVSPLADTLMEQLQ 9732
Cdd:cd00176 155 LEAHEPRLKSLNELAEELleEGHPDADEEIEEKLEELN 192
|
|
| SPEC |
smart00150 |
Spectrin repeats; |
12705-12810 |
1.29e-04 |
|
Spectrin repeats;
Pssm-ID: 197544 [Multi-domain] Cd Length: 101 Bit Score: 45.40 E-value: 1.29e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 320544544 12705 RLEERIALIRAWLFEVESQLDKPLNFESytPNVIEAKLKEHEQIQRSIEHHSSNVGEVLNLVEMLLNDADSwrtqvNTSG 12784
Cdd:smart00150 2 QFLRDADELEAWLEEKEQLLASEDLGKD--LESVEALLKKHEAFEAELEAHEERVEALNELGEQLIEEGHP-----DAEE 74
|
90 100
....*....|....*....|....*.
gi 320544544 12785 LAASAQNLEQRWKNVCSQSAERKARI 12810
Cdd:smart00150 75 IEERLEELNERWEELKELAEERRQKL 100
|
|
| SPEC |
smart00150 |
Spectrin repeats; |
13308-13376 |
1.30e-04 |
|
Spectrin repeats;
Pssm-ID: 197544 [Multi-domain] Cd Length: 101 Bit Score: 45.40 E-value: 1.30e-04
10 20 30 40 50 60 70
....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 320544544 13308 EFHQTIGELVEWLQRTEQNIKASE-PVDLTEersvLETKFKKFKDLRAELERCEPRVVSLQDAADQLLRS 13376
Cdd:smart00150 2 QFLRDADELEAWLEEKEQLLASEDlGKDLES----VEALLKKHEAFEAELEAHEERVEALNELGEQLIEE 67
|
|
| SMC_prok_B |
TIGR02168 |
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ... |
11268-12195 |
4.71e-04 |
|
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]
Pssm-ID: 274008 [Multi-domain] Cd Length: 1179 Bit Score: 48.13 E-value: 4.71e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 320544544 11268 EEKLDNYNQLNDELSTIKQNVVQLERQLSKAEpepqllqcvdSLKEHVDAVEQVTQQNQVQDSNDL-DKWHNFEvllynv 11346
Cdd:TIGR02168 182 ERTRENLDRLEDILNELERQLKSLERQAEKAE----------RYKELKAELRELELALLVLRLEELrEELEELQ------ 245
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 320544544 11347 sSVLADLQQSYDLLINQeypLSAKLAQLDELEQQHEAAQQQLAHLcqnarafQRDFpgkkmpqdvHNAFETSKNIANNIQ 11426
Cdd:TIGR02168 246 -EELKEAEEELEELTAE---LQELEEKLEELRLEVSELEEEIEEL-------QKEL---------YALANEISRLEQQKQ 305
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 320544544 11427 AERERVLQLQSLAEEYE-QTLKEFTKITVLADKLVEspiVSSSLEQLNNEVQKQRKFFVNLSHCRAMLESLEENIDSETR 11505
Cdd:TIGR02168 306 ILRERLANLERQLEELEaQLEELESKLDELAEELAE---LEEKLEELKEELESLEAELEELEAELEELESRLEELEEQLE 382
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 320544544 11506 EKHSELHkELYNRATSLldkASERSSklvqaasrwtvlekgMRDELQWLQVAQQRvpdLSAVTSAdydqyttlyqsLSND 11585
Cdd:TIGR02168 383 TLRSKVA-QLELQIASL---NNEIER---------------LEARLERLEDRRER---LQQEIEE-----------LLKK 429
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 320544544 11586 ISHHYVKMTQlSGIANKLQLLVQAPNLVEETNEALIvllKLREEVALYLHRLLVFKEIWVQYEQQTDKLEAFVREAEQEL 11665
Cdd:TIGR02168 430 LEEAELKELQ-AELEELEEELEELQEELERLEEALE---ELREELEEAEQALDAAERELAQLQARLDSLERLQENLEGFS 505
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 320544544 11666 RNIQIPSQPTHQPIEHMRQFWEIkarfelhnnVRTDTGlsFEKSLQVipLADEMLQrqfhAQLEDRWQAVAQAIE-LIQH 11744
Cdd:TIGR02168 506 EGVKALLKNQSGLSGILGVLSEL---------ISVDEG--YEAAIEA--ALGGRLQ----AVVVENLNAAKKAIAfLKQN 568
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 320544544 11745 NIVECLSSE-DVPADEKLKMVERE-LQEIYLTMTSMKGVIKNEEEL----------CLYIERVQ---------------- 11796
Cdd:TIGR02168 569 ELGRVTFLPlDSIKGTEIQGNDREiLKNIEGFLGVAKDLVKFDPKLrkalsyllggVLVVDDLDnalelakklrpgyriv 648
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 320544544 11797 ----VLRTRVGFI--GNELGRIGLQEPAIEPEKVGELFslshKISTQIAEELEGA-SVLRDQLQAIQEGISNQRKHQAKI 11869
Cdd:TIGR02168 649 tldgDLVRPGGVItgGSAKTNSSILERRREIEELEEKI----EELEEKIAELEKAlAELRKELEELEEELEQLRKELEEL 724
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 320544544 11870 SVILDECE---AAERQGADVLEKAVADCQAAGEELViswQEIMRIRQMLHTLPMRLK-MSVSPVKLERDISQLQDDHAFL 11945
Cdd:TIGR02168 725 SRQISALRkdlARLEAEVEQLEERIAQLSKELTELE---AEIEELEERLEEAEEELAeAEAEIEELEAQIEQLKEELKAL 801
|
730 740 750 760 770 780 790 800
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 320544544 11946 ESKCTNIMAILRsRLAVwlRYERQLELVHGSVQEtdfmMELIRVHGQVDYERLRKATERLEGLAGDLHNREQLIDELKGA 12025
Cdd:TIGR02168 802 REALDELRAELT-LLNE--EAANLRERLESLERR----IAATERRLEDLEEQIEELSEDIESLAAEIEELEELIEELESE 874
|
810 820 830 840 850 860 870 880
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 320544544 12026 AKPLIESCDVQIV--EQIESAVQEAVVAWNDTSENLQQLRTRYQRAVELWDKYRNASAAVKNSIDQQMDAVKSLEQplDA 12103
Cdd:TIGR02168 875 LEALLNERASLEEalALLRSELEELSEELRELESKRSELRRELEELREKLAQLELRLEGLEVRIDNLQERLSEEYS--LT 952
|
890 900 910 920 930 940 950 960
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 320544544 12104 LQHAKVCQDNLTTQNDRI-LELRDIVAKIAA--DVGLDASAlmqgELDALGQRL-------AECKDAITTLANVAETQDK 12173
Cdd:TIGR02168 953 LEEAEALENKIEDDEEEArRRLKRLENKIKElgPVNLAAIE----EYEELKERYdfltaqkEDLTEAKETLEEAIEEIDR 1028
|
970 980
....*....|....*....|..
gi 320544544 12174 ERKELDKEVtlakayFNNVQQD 12195
Cdd:TIGR02168 1029 EARERFKDT------FDQVNEN 1044
|
|
| SMC_prok_B |
TIGR02168 |
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ... |
75-351 |
5.04e-04 |
|
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]
Pssm-ID: 274008 [Multi-domain] Cd Length: 1179 Bit Score: 48.13 E-value: 5.04e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 320544544 75 IENCRnsEEKTLVQTTIDQLAASLAQVRGWLDEKKQAVGDSLDAWTRfmnlyqivmswasEKRNFIDQTIELRTLPEARN 154
Cdd:TIGR02168 679 IEELE--EKIEELEEKIAELEKALAELRKELEELEEELEQLRKELEE-------------LSRQISALRKDLARLEAEVE 743
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 320544544 155 KLNDYVTSvksikpIVKHLSEMDKELEhigqvttvgDLKDKLQEAEDAKISVEAVLLERNSLLQEACEEWDQCERKIKDI 234
Cdd:TIGR02168 744 QLEERIAQ------LSKELTELEAEIE---------ELEERLEEAEEELAEAEAEIEELEAQIEQLKEELKALREALDEL 808
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 320544544 235 RSWHEKTKQGLDSSQQQKKPLRDQLGFCEKTLADINVQKTKLRLSIEKLEvHFRNGMGGDPR------------------ 296
Cdd:TIGR02168 809 RAELTLLNEEAANLRERLESLERRIAATERRLEDLEEQIEELSEDIESLA-AEIEELEELIEeleseleallneraslee 887
|
250 260 270 280 290
....*....|....*....|....*....|....*....|....*....|....*....
gi 320544544 297 ----LSENVDDLVRVLDGLGELVKAKSQSLEQTLAQIDVYQQQMQSLRQRIIQEEQQLR 351
Cdd:TIGR02168 888 alalLRSELEELSEELRELESKRSELRRELEELREKLAQLELRLEGLEVRIDNLQERLS 946
|
|
| EnvC |
COG4942 |
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, ... |
194-393 |
5.04e-04 |
|
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, cell division, chromosome partitioning];
Pssm-ID: 443969 [Multi-domain] Cd Length: 377 Bit Score: 47.45 E-value: 5.04e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 320544544 194 DKLQEAEDAKISVEAVLLERNSLLQEAceewdqcERKIKDIRSWHEKTKQGLDSSQQQKKPLRDQLGFCEKTLADINVQK 273
Cdd:COG4942 20 DAAAEAEAELEQLQQEIAELEKELAAL-------KKEEKALLKQLAALERRIAALARRIRALEQELAALEAELAELEKEI 92
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 320544544 274 TKLRLSIEKLE--------VHFRNGMGGDPRL---SENVDDLVRVLDGLGELVKA-----------------KSQSLEQT 325
Cdd:COG4942 93 AELRAELEAQKeelaellrALYRLGRQPPLALllsPEDFLDAVRRLQYLKYLAPArreqaeelradlaelaaLRAELEAE 172
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 320544544 326 LAQIDVYQQQMQSLRQRIIQEEQQLRLVMA--PTYLPHDRERA---LAEQQAMRESIDGMQQVYDATARKSYA 393
Cdd:COG4942 173 RAELEALLAELEEERAALEALKAERQKLLArlEKELAELAAELaelQQEAEELEALIARLEAEAAAAAERTPA 245
|
|
| rne |
PRK10811 |
ribonuclease E; Reviewed |
10668-10827 |
1.81e-03 |
|
ribonuclease E; Reviewed
Pssm-ID: 236766 [Multi-domain] Cd Length: 1068 Bit Score: 46.19 E-value: 1.81e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 320544544 10668 EDAVVSSP--SESPRTPMVELVIPTEVVELA--LVEDEEQQTTPRIPSPTEKSEVEQDIKSVQTSPQHQPKLDETAV--- 10740
Cdd:PRK10811 861 AEEVQVQPvvAEVPVAAAVEPVVSAPVVEAVaeVVEEPVVVAEPQPEEVVVVETTHPEVIAAPVTEQPQVITESDVAvaq 940
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 320544544 10741 QTSLEVQPDNQENESQTLIVEITETEAQTTPRSEEQSVAVEISTTEIQTDVSGQPAETVEISSQTTVTTTIEKELQTTPK 10820
Cdd:PRK10811 941 EVAEHAEPVVEPQDETADIEEAAETAEVVVAEPEVVAQPAAPVVAEVAAEVETVTAVEPEVAPAQVPEATVEHNHATAPM 1020
|
....*..
gi 320544544 10821 DSPRAPE 10827
Cdd:PRK10811 1021 TRAPAPE 1027
|
|
| SPEC |
cd00176 |
Spectrin repeats, found in several proteins involved in cytoskeletal structure; family members ... |
11994-12156 |
2.52e-03 |
|
Spectrin repeats, found in several proteins involved in cytoskeletal structure; family members include spectrin, alpha-actinin and dystrophin; the spectrin repeat forms a three helix bundle with the second helix interrupted by proline in some sequences; the repeats are independent folding units; tandem repeats are found in differing numbers and arrange in an antiparallel manner to form dimers; the repeats are defined by a characteristic tryptophan (W) residue in helix A and a leucine (L) at the carboxyl end of helix C and separated by a linker of 5 residues; two copies of the repeat are present here
Pssm-ID: 238103 [Multi-domain] Cd Length: 213 Bit Score: 43.97 E-value: 2.52e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 320544544 11994 DYERLRKATERLEGLAGDLHNREQLIDELKGAAKPLIESCDVQIvEQIESAVQEAVVAWNDTSENLQQLRTRYQRAVELW 12073
Cdd:cd00176 31 DLESVEALLKKHEALEAELAAHEERVEALNELGEQLIEEGHPDA-EEIQERLEELNQRWEELRELAEERRQRLEEALDLQ 109
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 320544544 12074 DKYRNASAAV-----KNSIDQQMDAVKSLEQPLDALQHAKVCQDNLTTQNDRILELRDIVAKIAADVGLDASALMQGELD 12148
Cdd:cd00176 110 QFFRDADDLEqwleeKEAALASEDLGKDLESVEELLKKHKELEEELEAHEPRLKSLNELAEELLEEGHPDADEEIEEKLE 189
|
....*...
gi 320544544 12149 ALGQRLAE 12156
Cdd:cd00176 190 ELNERWEE 197
|
|
| SPEC |
smart00150 |
Spectrin repeats; |
9648-9742 |
2.59e-03 |
|
Spectrin repeats;
Pssm-ID: 197544 [Multi-domain] Cd Length: 101 Bit Score: 41.55 E-value: 2.59e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 320544544 9648 EYQQHLLELEQWIIEVSAELASfeptSDSSTDEQVLKSQVERSQQLLRTLKDRQQSMEDLVEQTRQL-QSHPDVSPLADT 9726
Cdd:smart00150 2 QFLRDADELEAWLEEKEQLLAS----EDLGKDLESVEALLKKHEAFEAELEAHEERVEALNELGEQLiEEGHPDAEEIEE 77
|
90
....*....|....*.
gi 320544544 9727 LMEQLQSIITILREQV 9742
Cdd:smart00150 78 RLEELNERWEELKELA 93
|
|
| Spectrin |
pfam00435 |
Spectrin repeat; Spectrin repeat-domains are found in several proteins involved in ... |
13308-13374 |
2.60e-03 |
|
Spectrin repeat; Spectrin repeat-domains are found in several proteins involved in cytoskeletal structure. These include spectrin, alpha-actinin and dystrophin. The sequence repeat used in this family is taken from the structural repeat in reference. The spectrin domain- repeat forms a three helix bundle. The second helix is interrupted by proline in some sequences. The repeats are defined by a characteriztic tryptophan (W) residue at position 17 in helix A and a leucine (L) at 2 residues from the carboxyl end of helix C. Although the domain occurs in multiple repeats along sequences, the domains are actually stable on their own - ie they act, biophysically, like domains rather than repeats that along function when aggregated.
Pssm-ID: 395348 [Multi-domain] Cd Length: 105 Bit Score: 41.54 E-value: 2.60e-03
10 20 30 40 50 60
....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 320544544 13308 EFHQTIGELVEWLQRTEQNIKASE-PVDLTEersvLETKFKKFKDLRAELERCEPRVVSLQDAADQLL 13374
Cdd:pfam00435 5 QFFRDADDLESWIEEKEALLSSEDyGKDLES----VQALLKKHKALEAELAAHQDRVEALNELAEKLI 68
|
|
| PRK11281 |
PRK11281 |
mechanosensitive channel MscK; |
12943-13105 |
3.53e-03 |
|
mechanosensitive channel MscK;
Pssm-ID: 236892 [Multi-domain] Cd Length: 1113 Bit Score: 45.29 E-value: 3.53e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 320544544 12943 SLNAIQKALEQLPSAENQQtskAEPKAVLQRLE-----------------SLEKKLQDAQQHVQQA----DNLAQEAKTR 13001
Cdd:PRK11281 37 TEADVQAQLDALNKQKLLE---AEDKLVQQDLEqtlalldkidrqkeeteQLKQQLAQAPAKLRQAqaelEALKDDNDEE 113
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 320544544 13002 TKQQ------PQLKQLLELVSAYTTLWQ----TVQTRIVTLKTtwLTRAAQAAaslpVSEAANAAVQVNTL------SQR 13065
Cdd:PRK11281 114 TRETlstlslRQLESRLAQTLDQLQNAQndlaEYNSQLVSLQT--QPERAQAA----LYANSQRLQQIRNLlkggkvGGK 187
|
170 180 190 200
....*....|....*....|....*....|....*....|....*
gi 320544544 13066 KLRQAQQMQRETSITAKDAYImELQTaiTECQNN-----LDELQR 13105
Cdd:PRK11281 188 ALRPSQRVLLQAEQALLNAQN-DLQR--KSLEGNtqlqdLLQKQR 229
|
|
| MukB |
COG3096 |
Chromosome condensin MukBEF, ATPase and DNA-binding subunit MukB [Cell cycle control, cell ... |
9538-9777 |
3.94e-03 |
|
Chromosome condensin MukBEF, ATPase and DNA-binding subunit MukB [Cell cycle control, cell division, chromosome partitioning];
Pssm-ID: 442330 [Multi-domain] Cd Length: 1470 Bit Score: 45.33 E-value: 3.94e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 320544544 9538 QRQKDLITQELDELLQSLSsvedgIANMNQSSLDGMLHGLKLIQSNLEVHE---------RDAIELKNQAKKLPtdpATE 9608
Cdd:COG3096 447 RAKEQQATEEVLELEQKLS-----VADAARRQFEKAYELVCKIAGEVERSQawqtarellRRYRSQQALAQRLQ---QLR 518
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 320544544 9609 RLLNDtvdrIDLLLRRTQQGITMIANAMHGQKKRQQEIDEYQQHLLELEQWIIEVSAELAsfeptsDSSTDEQVLKSQVE 9688
Cdd:COG3096 519 AQLAE----LEQRLRQQQNAERLLEEFCQRIGQQLDAAEELEELLAELEAQLEELEEQAA------EAVEQRSELRQQLE 588
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 320544544 9689 RSQQLLRTLKDR-------QQSMEDLVEQTRQ-LQSHPDVSPLADTLMEQLQSiITILREQVtVATKRifTIEKRIVDLR 9760
Cdd:COG3096 589 QLRARIKELAARapawlaaQDALERLREQSGEaLADSQEVTAAMQQLLERERE-ATVERDEL-AARKQ--ALESQIERLS 664
|
250
....*....|....*..
gi 320544544 9761 KAKSEEAQRQRVLADSL 9777
Cdd:COG3096 665 QPGGAEDPRLLALAERL 681
|
|
| CCDC158 |
pfam15921 |
Coiled-coil domain-containing protein 158; CCDC158 is a family of proteins found in eukaryotes. ... |
11276-11877 |
6.99e-03 |
|
Coiled-coil domain-containing protein 158; CCDC158 is a family of proteins found in eukaryotes. The function is not known.
Pssm-ID: 464943 [Multi-domain] Cd Length: 1112 Bit Score: 44.34 E-value: 6.99e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 320544544 11276 QLNDELSTIKQNVVQLERQLSKAEPEPQ----LLqcvdsLKEHVDAVEQVTQQNQVQDSNDLDKWHNFEVLLYNVSSVLA 11351
Cdd:pfam15921 228 ELDTEISYLKGRIFPVEDQLEALKSESQnkieLL-----LQQHQDRIEQLISEHEVEITGLTEKASSARSQANSIQSQLE 302
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 320544544 11352 DLQQSYDlliNQEyplSAKLAQLDELEQQHEAAQQQLAHlcqnarafqrdfpGKKMPQDVHNAFETSKNIANN--IQAER 11429
Cdd:pfam15921 303 IIQEQAR---NQN---SMYMRQLSDLESTVSQLRSELRE-------------AKRMYEDKIEELEKQLVLANSelTEART 363
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 320544544 11430 ERVL----------QLQSLAEEYEQTLKEFT----KITVLADKLVESPI----VSSSLEQLNNEVQKQRKFFVNL-SHCR 11490
Cdd:pfam15921 364 ERDQfsqesgnlddQLQKLLADLHKREKELSlekeQNKRLWDRDTGNSItidhLRRELDDRNMEVQRLEALLKAMkSECQ 443
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 320544544 11491 AMLESLEENID--SETREKHSELHKELyNRATSLLDKASER--SSKLVQAASRWTV--LEKGMRDELQWLQVAQQRVPDL 11564
Cdd:pfam15921 444 GQMERQMAAIQgkNESLEKVSSLTAQL-ESTKEMLRKVVEEltAKKMTLESSERTVsdLTASLQEKERAIEATNAEITKL 522
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 320544544 11565 SAVTSADYDQYttlyQSLSNDISHhyVKMTQLSGIANKLQLlVQAPNLVEETNEALIVLLKL-----REEVALYLHRLLV 11639
Cdd:pfam15921 523 RSRVDLKLQEL----QHLKNEGDH--LRNVQTECEALKLQM-AEKDKVIEILRQQIENMTQLvgqhgRTAGAMQVEKAQL 595
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 320544544 11640 FKEI------WVQYEQQTDKLEAFVREAEQELRNIQIPS-QPTHQPIEHMRQFWEIKA-RFELHNNVRTDtglsfEKSLQ 11711
Cdd:pfam15921 596 EKEIndrrleLQEFKILKDKKDAKIRELEARVSDLELEKvKLVNAGSERLRAVKDIKQeRDQLLNEVKTS-----RNELN 670
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 320544544 11712 VIPLADEMLQRQFHAQLEDrwqavaqaIELIQHNIveclssedvpaDEKLKMVERELQEIYLTMTSMKGVIKNEEELCLY 11791
Cdd:pfam15921 671 SLSEDYEVLKRNFRNKSEE--------METTTNKL-----------KMQLKSAQSELEQTRNTLKSMEGSDGHAMKVAMG 731
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 320544544 11792 IER--------VQVLRTRVGFIGNELGRIGLQEPAIEPEKVgelfSLSHKIST------QIAEELEgasVLRDQLQAIQE 11857
Cdd:pfam15921 732 MQKqitakrgqIDALQSKIQFLEEAMTNANKEKHFLKEEKN----KLSQELSTvateknKMAGELE---VLRSQERRLKE 804
|
650 660
....*....|....*....|
gi 320544544 11858 GISNQRKHQAKISVILDECE 11877
Cdd:pfam15921 805 KVANMEVALDKASLQFAECQ 824
|
|
| PTZ00121 |
PTZ00121 |
MAEBL; Provisional |
1704-1881 |
9.21e-03 |
|
MAEBL; Provisional
Pssm-ID: 173412 [Multi-domain] Cd Length: 2084 Bit Score: 43.98 E-value: 9.21e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 320544544 1704 AEVIKQAEEITQPELQELPAKVESptEPEVISEVVV-EQEQNKPQKPSRKDKKKQKLLENQPETVIETKV--------VE 1774
Cdd:PTZ00121 1718 AEELKKAEEENKIKAEEAKKEAEE--DKKKAEEAKKdEEEKKKIAHLKKEEEKKAEEIRKEKEAVIEEELdeedekrrME 1795
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 320544544 1775 IVKPQQEITEPQTEITEPLNTTSAITTDNNQTVSSEQTTVSDDSGLIKTTVIRTTKivKKISNNQQESQEMNSSTYSDAP 1854
Cdd:PTZ00121 1796 VDKKIKDIFDNFANIIEGGKEGNLVINDSKEMEDSAIKEVADSKNMQLEEADAFEK--HKFNKNNENGEDGNKEADFNKE 1873
|
170 180
....*....|....*....|....*..
gi 320544544 1855 SSLGSyDLAEEAIEPAKIEKSESNSRE 1881
Cdd:PTZ00121 1874 KDLKE-DDEEEIEEADEIEKIDKDDIE 1899
|
|
| |
|
Name |
Accession |
Description |
Interval |
E-value |
| KASH |
pfam10541 |
Nuclear envelope localization domain; The KASH (for Klarsicht/ANC-1/Syne-1 homology) or KLS ... |
13484-13540 |
3.26e-25 |
|
Nuclear envelope localization domain; The KASH (for Klarsicht/ANC-1/Syne-1 homology) or KLS domain is a highly hydrophobic nuclear envelope localization domain of approximately 60 amino acids comprising a 20-amino-acid transmembrane region and a 30-35-residue C-terminal region that lies between the inner and the outer nuclear membranes. During meiotic prophase, telomeres cluster to form a bouquet arrangement of chromosomes. SUN and KASH domain proteins form complexes that span both membranes of the nuclear envelope. The KASH domain links the dynein motor complex of the microtubules, through the outer nuclear membrane to the Sad1 domain in the inner nuclear membrane which then interacts with the bouquet proteins Bqt1 and Bqt2 that are complexed with Bqt4, Rap1 and Taz1 and attached to the telomere. SUN domain-containing proteins are essential for recruiting KASH domain proteins at the outer nuclear membrane, and KASH domains provide a generic NE tethering device for functionally distinct proteins whose cytoplasmic domains mediate nuclear positioning, maintain physical connections with other cellular organelles, and possibly even influence chromosome dynamics.
Pssm-ID: 463142 Cd Length: 58 Bit Score: 102.29 E-value: 3.26e-25
10 20 30 40 50
....*....|....*....|....*....|....*....|....*....|....*...
gi 320544544 13484 FLGRVARASLPIQALMLLLLGVATLVPHG-EDYTCMFSNTFARSLEPMLSYPHGPPPT 13540
Cdd:pfam10541 1 FLGRVLRAALPLQLLLLLLLLLACLLPAGeEDYSCTLANNFARSFHPMLRYVNGPPPT 58
|
|
| SPEC |
cd00176 |
Spectrin repeats, found in several proteins involved in cytoskeletal structure; family members ... |
13196-13374 |
6.61e-15 |
|
Spectrin repeats, found in several proteins involved in cytoskeletal structure; family members include spectrin, alpha-actinin and dystrophin; the spectrin repeat forms a three helix bundle with the second helix interrupted by proline in some sequences; the repeats are independent folding units; tandem repeats are found in differing numbers and arrange in an antiparallel manner to form dimers; the repeats are defined by a characteristic tryptophan (W) residue in helix A and a leucine (L) at the carboxyl end of helix C and separated by a linker of 5 residues; two copies of the repeat are present here
Pssm-ID: 238103 [Multi-domain] Cd Length: 213 Bit Score: 78.26 E-value: 6.61e-15
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 320544544 13196 WQQIDNDLWRLEQWLQfaESTQKAQSA-PPSNIELLEDVTQDHREFLLDLESHKSIISSLNVVGDHLAThtLDTEKARQL 13274
Cdd:cd00176 2 LQQFLRDADELEAWLS--EKEELLSSTdYGDDLESVEALLKKHEALEAELAAHEERVEALNELGEQLIE--EGHPDAEEI 77
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 320544544 13275 RSRLEADNERWNNVCINATKWQGLLQTALMGNSEFHQTIgELVEWLQRTEQNIKASEPVDLTEErsvLETKFKKFKDLRA 13354
Cdd:cd00176 78 QERLEELNQRWEELRELAEERRQRLEEALDLQQFFRDAD-DLEQWLEEKEAALASEDLGKDLES---VEELLKKHKELEE 153
|
170 180
....*....|....*....|
gi 320544544 13355 ELERCEPRVVSLQDAADQLL 13374
Cdd:cd00176 154 ELEAHEPRLKSLNELAEELL 173
|
|
| SMC_prok_B |
TIGR02168 |
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ... |
12205-12954 |
2.28e-14 |
|
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]
Pssm-ID: 274008 [Multi-domain] Cd Length: 1179 Bit Score: 82.41 E-value: 2.28e-14
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 320544544 12205 KESEEQLAALRAHLQTLartEEQLRQLKERHQNSEvapsvassdddgilEVLALWQKIFQDTFQEYHRLSTRLARSQNSs 12284
Cdd:TIGR02168 249 KEAEEELEELTAELQEL---EEKLEELRLEVSELE--------------EEIEELQKELYALANEISRLEQQKQILRER- 310
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 320544544 12285 ealrlwRQYLQHVQSFLSCAIPEDYSSLREQQQLCAihqnllisqqsvlsetplesELSEQYKALTNLHNETLSRIMQRN 12364
Cdd:TIGR02168 311 ------LANLERQLEELEAQLEELESKLDELAEELA--------------------ELEEKLEELKEELESLEAELEELE 364
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 320544544 12365 GELERRVSGWNAYRQQL----AALLDWLRQREAERNALQLRYIHLKRVPHLKHRLDAMIQQLDQgEQQSKALQEQQQELA 12440
Cdd:TIGR02168 365 AELEELESRLEELEEQLetlrSKVAQLELQIASLNNEIERLEARLERLEDRRERLQQEIEELLK-KLEEAELKELQAELE 443
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 320544544 12441 RH---CDDALATAMRMEQA--SIGQRISNLRAALKTWQGFLQRVTQLSESYEQRVNQLQQEFGAAQKLLDAN-------- 12507
Cdd:TIGR02168 444 ELeeeLEELQEELERLEEAleELREELEEAEQALDAAERELAQLQARLDSLERLQENLEGFSEGVKALLKNQsglsgilg 523
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 320544544 12508 --SESLPTQP---AAIEQLLGSlRAQRV---QLGAQVSALESLT------VTQEELKecISPHDMKTIRQRNWLLWQQ-- 12571
Cdd:TIGR02168 524 vlSELISVDEgyeAAIEAALGG-RLQAVvveNLNAAKKAIAFLKqnelgrVTFLPLD--SIKGTEIQGNDREILKNIEgf 600
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 320544544 12572 --------------HADLDYQLANLI--NSIEERLSLLSNYQIRY-------DRIS-----------QWLQRLEQRVEKD 12617
Cdd:TIGR02168 601 lgvakdlvkfdpklRKALSYLLGGVLvvDDLDNALELAKKLRPGYrivtldgDLVRpggvitggsakTNSSILERRREIE 680
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 320544544 12618 ADVTAMTNPEQAAKQLEQQVN---SELQLRDKEREWLLSTSRELLTLYSEPEVR-SQVQQQSDSLIDRWQRLKYLAKQKA 12693
Cdd:TIGR02168 681 ELEEKIEELEEKIAELEKALAelrKELEELEEELEQLRKELEELSRQISALRKDlARLEAEVEQLEERIAQLSKELTELE 760
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 320544544 12694 TKIGELKMTLLRLEERIALIRAWLFEVESQLDkplNFESYTPNVIEAKLKEHEQIQRsiehHSSNVGEVLNLVEMLLNDA 12773
Cdd:TIGR02168 761 AEIEELEERLEEAEEELAEAEAEIEELEAQIE---QLKEELKALREALDELRAELTL----LNEEAANLRERLESLERRI 833
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 320544544 12774 DSWRTQvntsglaasAQNLEQRWKNVCSQSAERKARILTIWNLLQQLIKLTAEHKNWLGKQESQI--AGFERDQKSHSKH 12851
Cdd:TIGR02168 834 AATERR---------LEDLEEQIEELSEDIESLAAEIEELEELIEELESELEALLNERASLEEALalLRSELEELSEELR 904
|
730 740 750 760 770 780 790 800
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 320544544 12852 KLEERQMELRAKLEELESQ--SVNLR------QLEQIYAKLAMSAGVEPENIQKLTLPTKVMVSMWR----QLTPRCHAL 12919
Cdd:TIGR02168 905 ELESKRSELRRELEELREKlaQLELRleglevRIDNLQERLSEEYSLTLEEAEALENKIEDDEEEARrrlkRLENKIKEL 984
|
810 820 830 840
....*....|....*....|....*....|....*....|..
gi 320544544 12920 ----LDAID--KDAKLMREFNNAQLE-ATNSLNAIQKALEQL 12954
Cdd:TIGR02168 985 gpvnLAAIEeyEELKERYDFLTAQKEdLTEAKETLEEAIEEI 1026
|
|
| mukB |
PRK04863 |
chromosome partition protein MukB; |
12163-13113 |
4.12e-14 |
|
chromosome partition protein MukB;
Pssm-ID: 235316 [Multi-domain] Cd Length: 1486 Bit Score: 81.54 E-value: 4.12e-14
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 320544544 12163 TLANVAETQdKERKELDKEVTLAKAYFNNvqqDISREAPQNPKESEEQLAALRAhlqtLARTEEQLRQLKERHQN--SEV 12240
Cdd:PRK04863 245 TLEAIRVTQ-SDRDLFKHLITESTNYVAA---DYMRHANERRVHLEEALELRRE----LYTSRRQLAAEQYRLVEmaREL 316
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 320544544 12241 ApsvASSDDDGILEvlalwqkifqdtfQEYHRLSTRLARSQNsseALRLWRQYLQHVQSFLscaipEDYSSLREQQQLCA 12320
Cdd:PRK04863 317 A---ELNEAESDLE-------------QDYQAASDHLNLVQT---ALRQQEKIERYQADLE-----ELEERLEEQNEVVE 372
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 320544544 12321 IHQNLLISQQSVLSETPLE-SELSEQykaltnlhnetLSRIMQRNGELERRVSgwnAYRQQLAAL--------------- 12384
Cdd:PRK04863 373 EADEQQEENEARAEAAEEEvDELKSQ-----------LADYQQALDVQQTRAI---QYQQAVQALerakqlcglpdltad 438
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 320544544 12385 --LDWLRQREAERNALQLRyihlkrVPHLKHRL---DAMIQQLDQGEQQSKAL-----QEQQQELARhcdDALATAMrmE 12454
Cdd:PRK04863 439 naEDWLEEFQAKEQEATEE------LLSLEQKLsvaQAAHSQFEQAYQLVRKIagevsRSEAWDVAR---ELLRRLR--E 507
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 320544544 12455 QASIGQRISNLRAALKTWQGFL---QRVTQLSESYEQRVNQ---LQQEFGAAQKLLDANSESLPTQPAAIEQLLGSLRAQ 12528
Cdd:PRK04863 508 QRHLAEQLQQLRMRLSELEQRLrqqQRAERLLAEFCKRLGKnldDEDELEQLQEELEARLESLSESVSEARERRMALRQQ 587
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 320544544 12529 RVQLGAQVSALESLT----VTQ---EELKECiSPHDMKTiRQRNWLLWQQHADLDYQLANLINSIEERLSLLsnyQIRYD 12601
Cdd:PRK04863 588 LEQLQARIQRLAARApawlAAQdalARLREQ-SGEEFED-SQDVTEYMQQLLERERELTVERDELAARKQAL---DEEIE 662
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 320544544 12602 RISQ-------WLQRLEQRV------EKDADVTAMTNPEQAAkqLEQQVNSELQLRDkerewLLSTSRELLTLYSEPEVR 12668
Cdd:PRK04863 663 RLSQpggsedpRLNALAERFggvllsEIYDDVSLEDAPYFSA--LYGPARHAIVVPD-----LSDAAEQLAGLEDCPEDL 735
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 320544544 12669 SQVQQQSDSLIDRWQRLKYLAKQKATKIGELKMTLLRL-----------EERIALIRAWLFEVESQLDKpLNFESytpnv 12737
Cdd:PRK04863 736 YLIEGDPDSFDDSVFSVEELEKAVVVKIADRQWRYSRFpevplfgraarEKRIEQLRAEREELAERYAT-LSFDV----- 809
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 320544544 12738 ieaklkehEQIQRSIEHHSSNVGEVLNLV-----EMLLNDADSWRTQVNTSGLAASAQNLEQRwknvcsqSAERKARilt 12812
Cdd:PRK04863 810 --------QKLQRLHQAFSRFIGSHLAVAfeadpEAELRQLNRRRVELERALADHESQEQQQR-------SQLEQAK--- 871
|
730 740 750 760 770 780 790 800
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 320544544 12813 iwNLLQQLIKLtaehknwlgkqESQIAGFERDQkshskhkLEERQMELRAKLEELE-------SQSVNLRQLEQIYAKLA 12885
Cdd:PRK04863 872 --EGLSALNRL-----------LPRLNLLADET-------LADRVEEIREQLDEAEeakrfvqQHGNALAQLEPIVSVLQ 931
|
810 820 830 840 850 860 870 880
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 320544544 12886 msagVEPENIQKLTLPTKVMVSMWRQLTPRCHALLDAIDKDAKLMREFNNAQLEATNSLNaiqkalEQLPsaenqqtska 12965
Cdd:PRK04863 932 ----SDPEQFEQLKQDYQQAQQTQRDAKQQAFALTEVVQRRAHFSYEDAAEMLAKNSDLN------EKLR---------- 991
|
890 900 910 920 930 940 950 960
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 320544544 12966 epkavlQRLESLEKKLQDAQQHVQQADNLAQEAKTRtkqqpqlkqLLELVSAYTTLWQTVQtrivtlkttwltRAAQAAA 13045
Cdd:PRK04863 992 ------QRLEQAEQERTRAREQLRQAQAQLAQYNQV---------LASLKSSYDAKRQMLQ------------ELKQELQ 1044
|
970 980 990 1000 1010 1020 1030
....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 320544544 13046 SLPV----SEAANAAVQVNTLSQRkLRQAQQmQREtsitakdayimELQTAITECQNNLDELQRTVVDKTRK 13113
Cdd:PRK04863 1045 DLGVpadsGAEERARARRDELHAR-LSANRS-RRN-----------QLEKQLTFCEAEMDNLTKKLRKLERD 1103
|
|
| COG4913 |
COG4913 |
Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown]; |
12265-12876 |
1.13e-13 |
|
Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];
Pssm-ID: 443941 [Multi-domain] Cd Length: 1089 Bit Score: 79.96 E-value: 1.13e-13
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 320544544 12265 DTFQEYH-RLSTRLARSqnSSEALRLWRQylqhVQSFlscaipEDYSSLREqqqlcaihqnlLISQQsVLSETPLES--- 12340
Cdd:COG4913 173 DSFSAYLaRLRRRLGIG--SEKALRLLHK----TQSF------KPIGDLDD-----------FVREY-MLEEPDTFEaad 228
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 320544544 12341 ELSEQYKALTNLHN---------ETLSRIMQRNGELERRVSGWNAYRQQLAALLDWLRQREAERnalqlryihlkrvphL 12411
Cdd:COG4913 229 ALVEHFDDLERAHEaledareqiELLEPIRELAERYAAARERLAELEYLRAALRLWFAQRRLEL---------------L 293
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 320544544 12412 KHRLDAMIQQLDQGEQQSKALQEQQQELARHCDDALAtamRMEQASiGQRISNLRAALKTWQGFLQRVTQLSESYEQRVN 12491
Cdd:COG4913 294 EAELEELRAELARLEAELERLEARLDALREELDELEA---QIRGNG-GDRLEQLEREIERLERELEERERRRARLEALLA 369
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 320544544 12492 QL-------QQEFGAAQKLLDANSESLPTQPAAIEQLLGSLRAQRVQLGAQVSALESltvTQEELKECIS--PHDMKTIR 12562
Cdd:COG4913 370 ALglplpasAEEFAALRAEAAALLEALEEELEALEEALAEAEAALRDLRRELRELEA---EIASLERRKSniPARLLALR 446
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 320544544 12563 QRnwllWQQH-----ADLDYqLANLI----------NSIE-----ERLSLLSNYQiRYDRISQWLQRLE-------QRVE 12615
Cdd:COG4913 447 DA----LAEAlgldeAELPF-VGELIevrpeeerwrGAIErvlggFALTLLVPPE-HYAAALRWVNRLHlrgrlvyERVR 520
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 320544544 12616 KDADVTAMTNPEQ---AAK--------------QLEQQ-----VNSELQLRDKERewllSTSRELLTlySEPEVRSQVQQ 12673
Cdd:COG4913 521 TGLPDPERPRLDPdslAGKldfkphpfrawleaELGRRfdyvcVDSPEELRRHPR----AITRAGQV--KGNGTRHEKDD 594
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 320544544 12674 QSDsLIDRW-------QRLKYLAKQkatkIGELKMTLLRLEERIALIRAWLFEVESQLDKPLNFESYTPNVIEAK--LKE 12744
Cdd:COG4913 595 RRR-IRSRYvlgfdnrAKLAALEAE----LAELEEELAEAEERLEALEAELDALQERREALQRLAEYSWDEIDVAsaERE 669
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 320544544 12745 HEQIQRSIEHHSSNVGEVLNLVEMLlndaDSWRTQVNTS-----GLAASAQNLEQRWKNvCSQSAERKARIltiwnlLQQ 12819
Cdd:COG4913 670 IAELEAELERLDASSDDLAALEEQL----EELEAELEELeeeldELKGEIGRLEKELEQ-AEEELDELQDR------LEA 738
|
650 660 670 680 690
....*....|....*....|....*....|....*....|....*....|....*..
gi 320544544 12820 LIKLTAEHKNWLGKQESQIAGFERDQKSHSKHkLEERQMELRAKLEELESQSVNLRQ 12876
Cdd:COG4913 739 AEDLARLELRALLEERFAAALGDAVERELREN-LEERIDALRARLNRAEEELERAMR 794
|
|
| sbcc |
TIGR00618 |
exonuclease SbcC; All proteins in this family for which functions are known are part of an ... |
12124-12885 |
5.59e-13 |
|
exonuclease SbcC; All proteins in this family for which functions are known are part of an exonuclease complex with sbcD homologs. This complex is involved in the initiation of recombination to regulate the levels of palindromic sequences in DNA. This family is based on the phylogenomic analysis of JA Eisen (1999, Ph.D. Thesis, Stanford University). [DNA metabolism, DNA replication, recombination, and repair]
Pssm-ID: 129705 [Multi-domain] Cd Length: 1042 Bit Score: 77.70 E-value: 5.59e-13
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 320544544 12124 LRDIVAKIAADVGLDASA------LMQGELDALgqRLAECKDAITTLANVAETQD---------KERKELDKEVTLAKAY 12188
Cdd:TIGR00618 125 KSETEEVIHDLLKLDYKTftrvvlLPQGEFAQF--LKAKSKEKKELLMNLFPLDQytqlalmefAKKKSLHGKAELLTLR 202
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 320544544 12189 FNNVQQDISrEAPQNPKESEEQLAALRAHL----QTLARTEEQLRQLKERHQNSEVapsvassdddgilevlalWQKIFQ 12264
Cdd:TIGR00618 203 SQLLTLCTP-CMPDTYHERKQVLEKELKHLrealQQTQQSHAYLTQKREAQEEQLK------------------KQQLLK 263
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 320544544 12265 DTFQEYHRLSTRLARSQNSSEAL---RLWRQYLQHVQSFLSC--AIPEDYSSLREQQ----QLCAIHQNLLISQQSVLSE 12335
Cdd:TIGR00618 264 QLRARIEELRAQEAVLEETQERInraRKAAPLAAHIKAVTQIeqQAQRIHTELQSKMrsraKLLMKRAAHVKQQSSIEEQ 343
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 320544544 12336 TPLESELSEQYKALTNLHNETLSR--IMQRNGELERRVSGWnayRQQLAALLDWLRQREAERNALQlRYIHLKRVPHLKH 12413
Cdd:TIGR00618 344 RRLLQTLHSQEIHIRDAHEVATSIreISCQQHTLTQHIHTL---QQQKTTLTQKLQSLCKELDILQ-REQATIDTRTSAF 419
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 320544544 12414 RldAMIQQLDQGEQQSKALQE--QQQELARHCDDALATAMRMEQASIGQRISNLRAALKTWQGFLQRVTQLSESYEQRVN 12491
Cdd:TIGR00618 420 R--DLQGQLAHAKKQQELQQRyaELCAAAITCTAQCEKLEKIHLQESAQSLKEREQQLQTKEQIHLQETRKKAVVLARLL 497
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 320544544 12492 QLQQefgaaqklldanseslptQPAAIEQLLGSLRAQRVQLGaqvsalesltvtqeelkecISPHD---MKTIRQRNWLL 12568
Cdd:TIGR00618 498 ELQE------------------EPCPLCGSCIHPNPARQDID-------------------NPGPLtrrMQRGEQTYAQL 540
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 320544544 12569 WQQHADLDYQLanliNSIEERLSLLSNYQIRYDRISQWLQRLEQRVEKDADVTamtnpeqaaKQLEQQVNSELQLRDKER 12648
Cdd:TIGR00618 541 ETSEEDVYHQL----TSERKQRASLKEQMQEIQQSFSILTQCDNRSKEDIPNL---------QNITVRLQDLTEKLSEAE 607
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 320544544 12649 EWLLSTSRELLTlysepEVRSQVQQQSDSLIDRwQRLKYLAKQKATKIGELkMTLLRLEERIALIRAWLFEVESqLDKPL 12728
Cdd:TIGR00618 608 DMLACEQHALLR-----KLQPEQDLQDVRLHLQ-QCSQELALKLTALHALQ-LTLTQERVREHALSIRVLPKEL-LASRQ 679
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 320544544 12729 NFESYTPNVIEA---KLKEHEQIQRSIEHHSSNVGEVLNLVEMLLNDADSWRT--QVNTSGLAASAQNLEQRWKNVCSQS 12803
Cdd:TIGR00618 680 LALQKMQSEKEQltyWKEMLAQCQTLLRELETHIEEYDREFNEIENASSSLGSdlAAREDALNQSLKELMHQARTVLKAR 759
|
730 740 750 760 770 780 790 800
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 320544544 12804 AERKARiltiwNLLQQLIKLT--AEHKNWLGKQESQIAGFERDQKShSKHKLEERQMELRAKLEELESQSVNLRQ-LEQI 12880
Cdd:TIGR00618 760 TEAHFN-----NNEEVTAALQtgAELSHLAAEIQFFNRLREEDTHL-LKTLEAEIGQEIPSDEDILNLQCETLVQeEEQF 833
|
....*
gi 320544544 12881 YAKLA 12885
Cdd:TIGR00618 834 LSRLE 838
|
|
| YhaN |
COG4717 |
Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown]; |
12338-12725 |
6.10e-12 |
|
Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown];
Pssm-ID: 443752 [Multi-domain] Cd Length: 641 Bit Score: 73.65 E-value: 6.10e-12
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 320544544 12338 LESELSEQYKALTNLHNETLSRIMQRNGELERRVSGWNAYRQQLAALLDWLRQREAERNALQLRYIHLKR---------- 12407
Cdd:COG4717 47 LLERLEKEADELFKPQGRKPELNLKELKELEEELKEAEEKEEEYAELQEELEELEEELEELEAELEELREeleklekllq 126
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 320544544 12408 -VPH------LKHRLDAMIQQLDQGEQQSKALQEQQQELAR------HCDDALATAMRMEQASIGQRISNLRAALKTWQG 12474
Cdd:COG4717 127 lLPLyqeleaLEAELAELPERLEELEERLEELRELEEELEEleaelaELQEELEELLEQLSLATEEELQDLAEELEELQQ 206
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 320544544 12475 FLQRVTQLSESYEQRVNQLQQEFGAAQKllDANSESLPTQPAAIEQLLGSLRAQRVQLGAQVSALESL------------ 12542
Cdd:COG4717 207 RLAELEEELEEAQEELEELEEELEQLEN--ELEAAALEERLKEARLLLLIAAALLALLGLGGSLLSLIltiagvlflvlg 284
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 320544544 12543 -------------TVTQEELKECISPHDMKTIRQRNWLLWqqHADLDYQLANLINSIEERLSLLSNYQIRYDRISQWLQR 12609
Cdd:COG4717 285 llallflllarekASLGKEAEELQALPALEELEEEELEEL--LAALGLPPDLSPEELLELLDRIEELQELLREAEELEEE 362
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 320544544 12610 LEQRVEKD--------ADVTAMTNPEQAAKQLEQQVNSELQLRDKER--EWLLSTSRELLTLYSEPEVRSQVQQQSDSLI 12679
Cdd:COG4717 363 LQLEELEQeiaallaeAGVEDEEELRAALEQAEEYQELKEELEELEEqlEELLGELEELLEALDEEELEEELEELEEELE 442
|
410 420 430 440
....*....|....*....|....*....|....*....|....*.
gi 320544544 12680 DRWQRLKYLAKQKATKIGELKMtlLRLEERIALIRAWLFEVESQLD 12725
Cdd:COG4717 443 ELEEELEELREELAELEAELEQ--LEEDGELAELLQELEELKAELR 486
|
|
| Smc |
COG1196 |
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ... |
12146-12753 |
4.45e-10 |
|
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];
Pssm-ID: 440809 [Multi-domain] Cd Length: 983 Bit Score: 68.04 E-value: 4.45e-10
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 320544544 12146 ELDALGQRLAECKDAITTLANVAETQDKERKELDKEVTLAKAYFNNVQQDIsreapqnpkesEEQLAALRAHLQTLARTE 12225
Cdd:COG1196 233 KLRELEAELEELEAELEELEAELEELEAELAELEAELEELRLELEELELEL-----------EEAQAEEYELLAELARLE 301
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 320544544 12226 EQLRQLKERHQNsevapsvASSDDDGILEVLALWQKIFQDTFQEYHRLSTRLARSQNSSEALRLwrqylqhvqsflscai 12305
Cdd:COG1196 302 QDIARLEERRRE-------LEERLEELEEELAELEEELEELEEELEELEEELEEAEEELEEAEA---------------- 358
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 320544544 12306 pEDYSSLREQQQLCAIHQNLLISQQSVLSEtpLESELSEQYKALTNLHN--ETLSRIMQRNGELERRVSGWNAYRQQLAA 12383
Cdd:COG1196 359 -ELAEAEEALLEAEAELAEAEEELEELAEE--LLEALRAAAELAAQLEEleEAEEALLERLERLEEELEELEEALAELEE 435
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 320544544 12384 LLDWLRQREAERNALQLRyihlkrvphLKHRLDAMIQQLDQGEQQSKALQEQQQELARhcddalatamrmEQASIGQRIS 12463
Cdd:COG1196 436 EEEEEEEALEEAAEEEAE---------LEEEEEALLELLAELLEEAALLEAALAELLE------------ELAEAAARLL 494
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 320544544 12464 NLRAALKTWQGFLQRVTQLsesyeqrvnQLQQEFGAAQKLLDANSESLPTQPAAIEQLLGSLRAQRV--QLGAQVSALES 12541
Cdd:COG1196 495 LLLEAEADYEGFLEGVKAA---------LLLAGLRGLAGAVAVLIGVEAAYEAALEAALAAALQNIVveDDEVAAAAIEY 565
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 320544544 12542 LTVTQEELKECISPHDMKTIRQRNWLLWQQHADLDYQL-ANLINSIEERLSLLSNY----QIRYDRISQWLQRLEQRVEK 12616
Cdd:COG1196 566 LKAAKAGRATFLPLDKIRARAALAAALARGAIGAAVDLvASDLREADARYYVLGDTllgrTLVAARLEAALRRAVTLAGR 645
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 320544544 12617 DADVT-AMTNPEQAAKQLEQQVNSELQLRDKEREWLLSTSRELLtlysepEVRSQVQQQSDSLIDRWQRLKYLAKQKATK 12695
Cdd:COG1196 646 LREVTlEGEGGSAGGSLTGGSRRELLAALLEAEAELEELAERLA------EEELELEEALLAEEEEERELAEAEEERLEE 719
|
570 580 590 600 610
....*....|....*....|....*....|....*....|....*....|....*...
gi 320544544 12696 IGELKMTLLRLEERIALIRAWLFEVESQLDKPLNFESYTPNVIEAKLKEHEQIQRSIE 12753
Cdd:COG1196 720 ELEEEALEEQLEAEREELLEELLEEEELLEEEALEELPEPPDLEELERELERLEREIE 777
|
|
| SMC_prok_B |
TIGR02168 |
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ... |
11822-12588 |
5.69e-10 |
|
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]
Pssm-ID: 274008 [Multi-domain] Cd Length: 1179 Bit Score: 67.77 E-value: 5.69e-10
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 320544544 11822 EKVGELFSLSHKISTqIAEELEGASVLRDQLQAIQEGISNQRKHQAKISVILDECEAAERQGADVLEKAVADCQAAGEEL 11901
Cdd:TIGR02168 285 ELQKELYALANEISR-LEQQKQILRERLANLERQLEELEAQLEELESKLDELAEELAELEEKLEELKEELESLEAELEEL 363
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 320544544 11902 VISWQEIMRIRQMLHTLPMRLKMSVSpvKLERDISQLQDDHAFLESKCTNI---MAILRSRLAVWLR--YERQLELVHGS 11976
Cdd:TIGR02168 364 EAELEELESRLEELEEQLETLRSKVA--QLELQIASLNNEIERLEARLERLedrRERLQQEIEELLKklEEAELKELQAE 441
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 320544544 11977 VQETDFMMELIRVHGQVDYERLRKATERLEGLAGDLHNREQLIDELKGAAKPLiescdVQIVEQIESAvQEAVVAWNDTS 12056
Cdd:TIGR02168 442 LEELEEELEELQEELERLEEALEELREELEEAEQALDAAERELAQLQARLDSL-----ERLQENLEGF-SEGVKALLKNQ 515
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 320544544 12057 ENLQQLRTRYQRAVELWDKYRNASAAVKNSiDQQMDAVKSLEQPLDALQHAKvcQDNLTTQNdrILELRDIVAKIAADVG 12136
Cdd:TIGR02168 516 SGLSGILGVLSELISVDEGYEAAIEAALGG-RLQAVVVENLNAAKKAIAFLK--QNELGRVT--FLPLDSIKGTEIQGND 590
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 320544544 12137 LDASALMQGELDALgQRLAECKDAITT-----LANVAETQDkerkeLDKEVTLAKAY---FNNVQQD---ISREAPQNPK 12205
Cdd:TIGR02168 591 REILKNIEGFLGVA-KDLVKFDPKLRKalsylLGGVLVVDD-----LDNALELAKKLrpgYRIVTLDgdlVRPGGVITGG 664
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 320544544 12206 ESEEQLAALrAHLQTLARTEEQLRQLKERHQNSEVAPSVASSDDDGILEVLALWQKIFQDTFQEYHRLSTRLARSQNSSE 12285
Cdd:TIGR02168 665 SAKTNSSIL-ERRREIEELEEKIEELEEKIAELEKALAELRKELEELEEELEQLRKELEELSRQISALRKDLARLEAEVE 743
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 320544544 12286 ALRLWRQYLQHVQSFLSCAIPEDYSSLREQQQLCAIHQNLLISQQSVLSE-----TPLESELSEQYKALTNLhNETLSRI 12360
Cdd:TIGR02168 744 QLEERIAQLSKELTELEAEIEELEERLEEAEEELAEAEAEIEELEAQIEQlkeelKALREALDELRAELTLL-NEEAANL 822
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 320544544 12361 MQRNGELERRVSGWNAYRQQLAALLDWLRQREAERNALQLRYIHLKRVphLKHRLDAMIQQLDQGEQQSKALQEQQQELA 12440
Cdd:TIGR02168 823 RERLESLERRIAATERRLEDLEEQIEELSEDIESLAAEIEELEELIEE--LESELEALLNERASLEEALALLRSELEELS 900
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 320544544 12441 RHCDDALATAMRMEQASIGQRISNLRAALKtWQGFLQRVTQLSEsyeqrvnQLQQEFGAAQKLLDANSESLPTQPAAIEQ 12520
Cdd:TIGR02168 901 EELRELESKRSELRRELEELREKLAQLELR-LEGLEVRIDNLQE-------RLSEEYSLTLEEAEALENKIEDDEEEARR 972
|
730 740 750 760 770 780
....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 320544544 12521 LLGSLRAQRVQLGA-QVSALESLtvtqEELKEcisphdmktiRQRNwlLWQQHADLDYQLANLINSIEE 12588
Cdd:TIGR02168 973 RLKRLENKIKELGPvNLAAIEEY----EELKE----------RYDF--LTAQKEDLTEAKETLEEAIEE 1025
|
|
| Smc |
COG1196 |
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ... |
12355-12983 |
6.73e-10 |
|
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];
Pssm-ID: 440809 [Multi-domain] Cd Length: 983 Bit Score: 67.27 E-value: 6.73e-10
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 320544544 12355 ETLSRI--MQRN--------GELERRVsgwnayrQQLA----------ALLDWLRQREAERNALQLRyihlkrvpHLKHR 12414
Cdd:COG1196 176 EAERKLeaTEENlerledilGELERQL-------EPLErqaekaeryrELKEELKELEAELLLLKLR--------ELEAE 240
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 320544544 12415 LDAMIQQLDQGEQQSKALQEQQQEL---------ARHCDDALATAMRMEQASIGQRISNLRAALKTWQGFLQRVTQLSES 12485
Cdd:COG1196 241 LEELEAELEELEAELEELEAELAELeaeleelrlELEELELELEEAQAEEYELLAELARLEQDIARLEERRRELEERLEE 320
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 320544544 12486 YEQRVNQLQQEFGAAQKLLDANSESLptqpAAIEQLLGSLRAQRVQLGAQVSALESLTVTQEELKEcisphdmktirqrn 12565
Cdd:COG1196 321 LEEELAELEEELEELEEELEELEEEL----EEAEEELEEAEAELAEAEEALLEAEAELAEAEEELE-------------- 382
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 320544544 12566 wLLWQQHADLDYQLANLINSIEERLSLLSNYQIRYDRisqwlqRLEQRVEKDADVTAMTNPEQAAKQLEQQVNSELQLRD 12645
Cdd:COG1196 383 -ELAEELLEALRAAAELAAQLEELEEAEEALLERLER------LEEELEELEEALAELEEEEEEEEEALEEAAEEEAELE 455
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 320544544 12646 KEREWLLSTSRELltLYSEPEVRSQVQQQSDSLIDRWQRLK--------YLAKQKATKIGELKMTLLRLEERIALIRAWL 12717
Cdd:COG1196 456 EEEEALLELLAEL--LEEAALLEAALAELLEELAEAAARLLllleaeadYEGFLEGVKAALLLAGLRGLAGAVAVLIGVE 533
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 320544544 12718 FEVESQLDKPLNfesytPNVIEAKLKEHEQIQRSIEHHSSNVGEVLNLVEMLLNDADSWRTQVNTSGLAASAQNL---EQ 12794
Cdd:COG1196 534 AAYEAALEAALA-----AALQNIVVEDDEVAAAAIEYLKAAKAGRATFLPLDKIRARAALAAALARGAIGAAVDLvasDL 608
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 320544544 12795 RWKNVCSQSAERKARILTIWN------------LLQQLIKLTAEHKnwLGKQESQIAGFERDQKSHSKHKLEERQMELRA 12862
Cdd:COG1196 609 READARYYVLGDTLLGRTLVAarleaalrravtLAGRLREVTLEGE--GGSAGGSLTGGSRRELLAALLEAEAELEELAE 686
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 320544544 12863 KLEELESQSVNLRQLE---QIYAKLAMSAGVEPENIQKLTLPTKVMVSMWRQLTPRCHALLDAIDKDAKLMREFNNAQLE 12939
Cdd:COG1196 687 RLAEEELELEEALLAEeeeERELAEAEEERLEEELEEEALEEQLEAEREELLEELLEEEELLEEEALEELPEPPDLEELE 766
|
650 660 670 680
....*....|....*....|....*....|....*....|....*...
gi 320544544 12940 AtnSLNAIQKALEQL----PSAENQQtskaepKAVLQRLESLEKKLQD 12983
Cdd:COG1196 767 R--ELERLEREIEALgpvnLLAIEEY------EELEERYDFLSEQRED 806
|
|
| sbcc |
TIGR00618 |
exonuclease SbcC; All proteins in this family for which functions are known are part of an ... |
12338-13013 |
7.29e-10 |
|
exonuclease SbcC; All proteins in this family for which functions are known are part of an exonuclease complex with sbcD homologs. This complex is involved in the initiation of recombination to regulate the levels of palindromic sequences in DNA. This family is based on the phylogenomic analysis of JA Eisen (1999, Ph.D. Thesis, Stanford University). [DNA metabolism, DNA replication, recombination, and repair]
Pssm-ID: 129705 [Multi-domain] Cd Length: 1042 Bit Score: 67.30 E-value: 7.29e-10
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 320544544 12338 LESELSEQYKALTNLHnETLSRIMQRNGELERRVSgWNAYRQQLAALLDWLRQREAE----RNALQLRYIHLKRVPHLKH 12413
Cdd:TIGR00618 224 LEKELKHLREALQQTQ-QSHAYLTQKREAQEEQLK-KQQLLKQLRARIEELRAQEAVleetQERINRARKAAPLAAHIKA 301
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 320544544 12414 rldamIQQLDQGEQQSKA-LQEQQQELARhcddalATAMRMEQASIGQRISNLRAALKTWQGFLQRVTQLSESYEQRVNQ 12492
Cdd:TIGR00618 302 -----VTQIEQQAQRIHTeLQSKMRSRAK------LLMKRAAHVKQQSSIEEQRRLLQTLHSQEIHIRDAHEVATSIREI 370
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 320544544 12493 LQQEFGAAQKLLdanseSLPTQPAAIEQLLGSLRAQRVQLGAQVSALESLTVTQEELK-ECISPHDMKTIRQRNWLLWQQ 12571
Cdd:TIGR00618 371 SCQQHTLTQHIH-----TLQQQKTTLTQKLQSLCKELDILQREQATIDTRTSAFRDLQgQLAHAKKQQELQQRYAELCAA 445
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 320544544 12572 HADLDYQLANLINSIEERLSllsnyqirydrisqwlQRLEQRVEKDADVTAMTNPEQAAKQLEQQVNSELQLRDKEREWL 12651
Cdd:TIGR00618 446 AITCTAQCEKLEKIHLQESA----------------QSLKEREQQLQTKEQIHLQETRKKAVVLARLLELQEEPCPLCGS 509
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 320544544 12652 LSTSRELLTLYSEPEVRSQVQQQsdsLIDRWQRLKYLAKQKATKIGELKMTLLRLEERIALIRAWLF-------EVESQL 12724
Cdd:TIGR00618 510 CIHPNPARQDIDNPGPLTRRMQR---GEQTYAQLETSEEDVYHQLTSERKQRASLKEQMQEIQQSFSiltqcdnRSKEDI 586
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 320544544 12725 DKPLNFESYTPNVIEAKLKEHEQIQRSIEHHSSNVGEVLNLVEMLLNDAD-SWRTQVNTSGLAASAQNLEQ-----RWKN 12798
Cdd:TIGR00618 587 PNLQNITVRLQDLTEKLSEAEDMLACEQHALLRKLQPEQDLQDVRLHLQQcSQELALKLTALHALQLTLTQervreHALS 666
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 320544544 12799 VCSQSAERKARILTIWNLLQQLIKLTAEHKNWLGKQESQIAGFERDQKSHSKHkLEERQMELRAKLEELESQSVNLRQLE 12878
Cdd:TIGR00618 667 IRVLPKELLASRQLALQKMQSEKEQLTYWKEMLAQCQTLLRELETHIEEYDRE-FNEIENASSSLGSDLAAREDALNQSL 745
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 320544544 12879 QIYAKLAMSAGVEPENIQKLTLPTKVMVSMwrqltprchalLDAIDKDAKLMREFNNAQLEATNSLNAIQKAL--EQLPS 12956
Cdd:TIGR00618 746 KELMHQARTVLKARTEAHFNNNEEVTAALQ-----------TGAELSHLAAEIQFFNRLREEDTHLLKTLEAEigQEIPS 814
|
650 660 670 680 690 700
....*....|....*....|....*....|....*....|....*....|....*....|..
gi 320544544 12957 AE-----NQQTSKAEPKAVLQRLESLEKKLQDAQQHVQQADNLAQEAKTRTKQQPQLKQLLE 13013
Cdd:TIGR00618 815 DEdilnlQCETLVQEEEQFLSRLEEKSATLGEITHQLLKYEECSKQLAQLTQEQAKIIQLSD 876
|
|
| COG4913 |
COG4913 |
Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown]; |
11877-12660 |
8.34e-10 |
|
Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];
Pssm-ID: 443941 [Multi-domain] Cd Length: 1089 Bit Score: 67.25 E-value: 8.34e-10
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 320544544 11877 EAAERQgADVLEKAVADCQAAGEElvisWQEIMRIRQMLHTLPM---RLKMSVspvkLERDISQLQDDHAFLESKctnim 11953
Cdd:COG4913 245 EDAREQ-IELLEPIRELAERYAAA----RERLAELEYLRAALRLwfaQRRLEL----LEAELEELRAELARLEAE----- 310
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 320544544 11954 ailRSRLavwlryERQLELVHGSVQEtdfmmeLIRVHGQVDYERLRKATERLEGLAGDLHNREQLIDELKGAAKPLiesc 12033
Cdd:COG4913 311 ---LERL------EARLDALREELDE------LEAQIRGNGGDRLEQLEREIERLERELEERERRRARLEALLAAL---- 371
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 320544544 12034 dvqiveQIESAVQEAVVAwndtsENLQQLRTRYQRAVELWDKYRNASAAVKNSIDQQMDAVKSLEQPLDALQHAKVCQDn 12113
Cdd:COG4913 372 ------GLPLPASAEEFA-----ALRAEAAALLEALEEELEALEEALAEAEAALRDLRRELRELEAEIASLERRKSNIP- 439
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 320544544 12114 lttqnDRILELRDivaKIAADVGLDASALM-QGELDALGQRLAECKDAIttlanvaetqdkERkeldkevtlakaYFNNV 12192
Cdd:COG4913 440 -----ARLLALRD---ALAEALGLDEAELPfVGELIEVRPEEERWRGAI------------ER------------VLGGF 487
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 320544544 12193 QQDISREapqnpkesEEQLAALRAHLQTLaRTEEQLRQLKERHQNSEVAPSVAssDDDGILEVLAlwqkiFQDT-FQEYh 12271
Cdd:COG4913 488 ALTLLVP--------PEHYAAALRWVNRL-HLRGRLVYERVRTGLPDPERPRL--DPDSLAGKLD-----FKPHpFRAW- 550
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 320544544 12272 rLSTRLARSQNssealrlwrqylqhvqsFLSCAIPEDyssLREQQQlcAIHQNLLISqqsvlsetpleselseqykaltn 12351
Cdd:COG4913 551 -LEAELGRRFD-----------------YVCVDSPEE---LRRHPR--AITRAGQVK----------------------- 584
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 320544544 12352 lHNETLSRIMQRNGELERRVSGWNAyRQQLAALldwlrqrEAERNALQLRyihlkrvphlKHRLDAMIQQLDQGEQQSKA 12431
Cdd:COG4913 585 -GNGTRHEKDDRRRIRSRYVLGFDN-RAKLAAL-------EAELAELEEE----------LAEAEERLEALEAELDALQE 645
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 320544544 12432 LQEQQQELARHCDDALATAM-RMEQASIGQRISNLRAAlktwQGFLQRVTQLSESYEQRVNQLQQEFGAAQKLLDANSES 12510
Cdd:COG4913 646 RREALQRLAEYSWDEIDVASaEREIAELEAELERLDAS----SDDLAALEEQLEELEAELEELEEELDELKGEIGRLEKE 721
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 320544544 12511 LptqpAAIEQLLGSLRAQRVQLGAQVSALESLTVtQEELKECISPHDMKTIRQRnwlLWQQHADLDYQLANLINSIEErl 12590
Cdd:COG4913 722 L----EQAEEELDELQDRLEAAEDLARLELRALL-EERFAAALGDAVERELREN---LEERIDALRARLNRAEEELER-- 791
|
730 740 750 760 770 780 790
....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 320544544 12591 sLLSNYQIRYDRISQwlqrleqrvekDADVTAMTNPEqAAKQLEQQVNSEL-QLRDKEREWLLSTSRELLT 12660
Cdd:COG4913 792 -AMRAFNREWPAETA-----------DLDADLESLPE-YLALLDRLEEDGLpEYEERFKELLNENSIEFVA 849
|
|
| SPEC |
cd00176 |
Spectrin repeats, found in several proteins involved in cytoskeletal structure; family members ... |
12703-12923 |
2.04e-09 |
|
Spectrin repeats, found in several proteins involved in cytoskeletal structure; family members include spectrin, alpha-actinin and dystrophin; the spectrin repeat forms a three helix bundle with the second helix interrupted by proline in some sequences; the repeats are independent folding units; tandem repeats are found in differing numbers and arrange in an antiparallel manner to form dimers; the repeats are defined by a characteristic tryptophan (W) residue in helix A and a leucine (L) at the carboxyl end of helix C and separated by a linker of 5 residues; two copies of the repeat are present here
Pssm-ID: 238103 [Multi-domain] Cd Length: 213 Bit Score: 62.08 E-value: 2.04e-09
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 320544544 12703 LLRLEERIALIRAWLFEVESQLDKPLNfeSYTPNVIEAKLKEHEQIQRSIEHHSSNVGEVLNLVEMLLNDAdswrtQVNT 12782
Cdd:cd00176 2 LQQFLRDADELEAWLSEKEELLSSTDY--GDDLESVEALLKKHEALEAELAAHEERVEALNELGEQLIEEG-----HPDA 74
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 320544544 12783 SGLAASAQNLEQRWKNVCSQSAERKARILTIWNLLQQLIKLTAEhKNWLGKQESQIAgfeRDQKSHSKHKLEERQMELRA 12862
Cdd:cd00176 75 EEIQERLEELNQRWEELRELAEERRQRLEEALDLQQFFRDADDL-EQWLEEKEAALA---SEDLGKDLESVEELLKKHKE 150
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 320544544 12863 KLEELESQSVNLRQLEQIYAKLAMSAgvEPENIQKLTLPTKVMVSMWRQL----TPRCHALLDAI 12923
Cdd:cd00176 151 LEEELEAHEPRLKSLNELAEELLEEG--HPDADEEIEEKLEELNERWEELlelaEERQKKLEEAL 213
|
|
| SPEC |
cd00176 |
Spectrin repeats, found in several proteins involved in cytoskeletal structure; family members ... |
12596-12809 |
2.60e-09 |
|
Spectrin repeats, found in several proteins involved in cytoskeletal structure; family members include spectrin, alpha-actinin and dystrophin; the spectrin repeat forms a three helix bundle with the second helix interrupted by proline in some sequences; the repeats are independent folding units; tandem repeats are found in differing numbers and arrange in an antiparallel manner to form dimers; the repeats are defined by a characteristic tryptophan (W) residue in helix A and a leucine (L) at the carboxyl end of helix C and separated by a linker of 5 residues; two copies of the repeat are present here
Pssm-ID: 238103 [Multi-domain] Cd Length: 213 Bit Score: 61.69 E-value: 2.60e-09
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 320544544 12596 YQIRYDRISQWLQRLEQRVEKDADVTAMTNPEQAAKQLeQQVNSELQLRDKEREWLLSTSRELLTLYSEPEvrSQVQQQS 12675
Cdd:cd00176 5 FLRDADELEAWLSEKEELLSSTDYGDDLESVEALLKKH-EALEAELAAHEERVEALNELGEQLIEEGHPDA--EEIQERL 81
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 320544544 12676 DSLIDRWQRLKYLAKQKATKIGELKMTLLRLEErIALIRAWLFEVESQLDKPLNFESYTPnvIEAKLKEHEQIQRSIEHH 12755
Cdd:cd00176 82 EELNQRWEELRELAEERRQRLEEALDLQQFFRD-ADDLEQWLEEKEAALASEDLGKDLES--VEELLKKHKELEEELEAH 158
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|....
gi 320544544 12756 SSNVGEVLNLVEMLLNDADSWRTQVntsgLAASAQNLEQRWKNVCSQSAERKAR 12809
Cdd:cd00176 159 EPRLKSLNELAEELLEEGHPDADEE----IEEKLEELNERWEELLELAEERQKK 208
|
|
| Smc |
COG1196 |
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ... |
12122-12711 |
2.94e-09 |
|
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];
Pssm-ID: 440809 [Multi-domain] Cd Length: 983 Bit Score: 65.34 E-value: 2.94e-09
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 320544544 12122 LELRDIVAKIAADVGLDAS-ALMQGELDALGQRLAECKDAITTLANVAETQDKERKELDKEVTLAKAYFNNVQQDISREA 12200
Cdd:COG1196 222 LKELEAELLLLKLRELEAElEELEAELEELEAELEELEAELAELEAELEELRLELEELELELEEAQAEEYELLAELARLE 301
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 320544544 12201 pqnpKESEEQLAALRAHLQTLARTEEQLRQLKERHQNSEVAPSVASSDDDGILEVLALWQKIFQDTFQEYHRLSTRLARS 12280
Cdd:COG1196 302 ----QDIARLEERRRELEERLEELEEELAELEEELEELEEELEELEEELEEAEEELEEAEAELAEAEEALLEAEAELAEA 377
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 320544544 12281 QnsSEALRLWRQYLQHVQsflscaipEDYSSLREQQQLCAIHQNLLISQQSVLSEtplESELSEQYKALTNLHNETLSRI 12360
Cdd:COG1196 378 E--EELEELAEELLEALR--------AAAELAAQLEELEEAEEALLERLERLEEE---LEELEEALAELEEEEEEEEEAL 444
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 320544544 12361 MQRNGELERRVSGWNAYRQQLAALLDWLRQREAERNALQLRYIHLKRvphLKHRLDAMIQQLDQGEQQSKALQ--EQQQE 12438
Cdd:COG1196 445 EEAAEEEAELEEEEEALLELLAELLEEAALLEAALAELLEELAEAAA---RLLLLLEAEADYEGFLEGVKAALllAGLRG 521
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 320544544 12439 LARHCDDALATAMRMEQAsigqrisnLRAALKTWQgfLQRVTQLSESYEQRVNQLQQEFGAAQKLLDANSESLPTQPAAI 12518
Cdd:COG1196 522 LAGAVAVLIGVEAAYEAA--------LEAALAAAL--QNIVVEDDEVAAAAIEYLKAAKAGRATFLPLDKIRARAALAAA 591
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 320544544 12519 EQLLGSLRAQRVQLGAQVSALESLTVTQEELKEcispHDMKTIRQRNWLLWQQHADLDY--------------QLANLIN 12584
Cdd:COG1196 592 LARGAIGAAVDLVASDLREADARYYVLGDTLLG----RTLVAARLEAALRRAVTLAGRLrevtlegeggsaggSLTGGSR 667
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 320544544 12585 SIEERLSLLSNYQIRYDRISQWLQRLEQRVEKDADVTAMTNPEQAAKQLEQQVNSELQLRDKEREWLLSTSRELLTLYS- 12663
Cdd:COG1196 668 RELLAALLEAEAELEELAERLAEEELELEEALLAEEEEERELAEAEEERLEEELEEEALEEQLEAEREELLEELLEEEEl 747
|
570 580 590 600 610 620 630
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 320544544 12664 ----------EPEVRSQVQQQSDSL---IDRW---------------QRLKYLAKQKATKIGELKmtllRLEERIA 12711
Cdd:COG1196 748 leeealeelpEPPDLEELERELERLereIEALgpvnllaieeyeeleERYDFLSEQREDLEEARE----TLEEAIE 819
|
|
| YhaN |
COG4717 |
Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown]; |
12087-12551 |
4.27e-09 |
|
Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown];
Pssm-ID: 443752 [Multi-domain] Cd Length: 641 Bit Score: 64.40 E-value: 4.27e-09
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 320544544 12087 IDQQMDAVKSLEQPLDALQHAkvcQDNLTTQNDRILELRDIVAKIAADVGLDASALMQGELDALGQRLAECKDAITTLAN 12166
Cdd:COG4717 73 LKELEEELKEAEEKEEEYAEL---QEELEELEEELEELEAELEELREELEKLEKLLQLLPLYQELEALEAELAELPERLE 149
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 320544544 12167 VAETQDKERKELDKEVTLAKAYFNNVQQDISREAPQNPKESEEQLAALRAHLQTLARTEEQLRQLKERHQNSEVAPSVAS 12246
Cdd:COG4717 150 ELEERLEELRELEEELEELEAELAELQEELEELLEQLSLATEEELQDLAEELEELQQRLAELEEELEEAQEELEELEEEL 229
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 320544544 12247 SDDDGILEVLALWQKIfQDTFQEYHRLSTRLARSQNSSEALRLWRQYLQHVQSFLSCAIPEDYSSLREQQQLCAihqnll 12326
Cdd:COG4717 230 EQLENELEAAALEERL-KEARLLLLIAAALLALLGLGGSLLSLILTIAGVLFLVLGLLALLFLLLAREKASLGK------ 302
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 320544544 12327 isqqsvlsetplESELSEQYKALTNLHNETLSRIMQRNG-ELERRVSGWNAYRQQLAALLDWLRQREAERNALQLRYIHL 12405
Cdd:COG4717 303 ------------EAEELQALPALEELEEEELEELLAALGlPPDLSPEELLELLDRIEELQELLREAEELEEELQLEELEQ 370
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 320544544 12406 KRVPHLKH-------RLDAMIQQLDQGEQQSKALQEQQQELARHCDDALATAMRMEQASIGQRISNLRAALktwqgflqr 12478
Cdd:COG4717 371 EIAALLAEagvedeeELRAALEQAEEYQELKEELEELEEQLEELLGELEELLEALDEEELEEELEELEEEL--------- 441
|
410 420 430 440 450 460 470
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 320544544 12479 vtqlsESYEQRVNQLQQEFGAAQKLLDA--NSESLPTQPAAIEQLLGSLRAQRVQLGAQVSALESLTVTQEELKE 12551
Cdd:COG4717 442 -----EELEEELEELREELAELEAELEQleEDGELAELLQELEELKAELRELAEEWAALKLALELLEEAREEYRE 511
|
|
| SPEC |
cd00176 |
Spectrin repeats, found in several proteins involved in cytoskeletal structure; family members ... |
17-220 |
5.12e-09 |
|
Spectrin repeats, found in several proteins involved in cytoskeletal structure; family members include spectrin, alpha-actinin and dystrophin; the spectrin repeat forms a three helix bundle with the second helix interrupted by proline in some sequences; the repeats are independent folding units; tandem repeats are found in differing numbers and arrange in an antiparallel manner to form dimers; the repeats are defined by a characteristic tryptophan (W) residue in helix A and a leucine (L) at the carboxyl end of helix C and separated by a linker of 5 residues; two copies of the repeat are present here
Pssm-ID: 238103 [Multi-domain] Cd Length: 213 Bit Score: 60.92 E-value: 5.12e-09
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 320544544 17 EYVDGVDEVQRWLLQAEVQVQERSL--TPTQMKELLQR---INHEITAIYERFTLVKTNGQLIIEncRNSEEKTLVQTTI 91
Cdd:cd00176 4 QFLRDADELEAWLSEKEELLSSTDYgdDLESVEALLKKheaLEAELAAHEERVEALNELGEQLIE--EGHPDAEEIQERL 81
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 320544544 92 DQLAASLAQVRGWLDEKKQAVGDSLDAWtRFMNLYQIVMSWASEKRNFIDQTIELRTLPEARNKLN---DYVTSVKSIKP 168
Cdd:cd00176 82 EELNQRWEELRELAEERRQRLEEALDLQ-QFFRDADDLEQWLEEKEAALASEDLGKDLESVEELLKkhkELEEELEAHEP 160
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|..
gi 320544544 169 IVKHLSEMDKELEHIGQVTTVGDLKDKLQEAEDAKISVEAVLLERNSLLQEA 220
Cdd:cd00176 161 RLKSLNELAEELLEEGHPDADEEIEEKLEELNERWEELLELAEERQKKLEEA 212
|
|
| COG4913 |
COG4913 |
Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown]; |
11981-12541 |
9.67e-09 |
|
Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];
Pssm-ID: 443941 [Multi-domain] Cd Length: 1089 Bit Score: 63.78 E-value: 9.67e-09
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 320544544 11981 DFMMELIRVHGQVdyERLRKATERLEGLAGD------LHNREQLIDELKGAAKPLIescDVQIVEQIESAVQEAVVAWND 12054
Cdd:COG4913 232 EHFDDLERAHEAL--EDAREQIELLEPIRELaeryaaARERLAELEYLRAALRLWF---AQRRLELLEAELEELRAELAR 306
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 320544544 12055 TSENLQQLRTRYQRAVELWDKYRNASAAVKNsidqqmDAVKSLEQPLDALQHAkvcqdnLTTQNDRILELRDIVAKIAAD 12134
Cdd:COG4913 307 LEAELERLEARLDALREELDELEAQIRGNGG------DRLEQLEREIERLERE------LEERERRRARLEALLAALGLP 374
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 320544544 12135 VGLDASAL------MQGELDALGQRLAECKDAITTLANVAETQDKERKELDKEVT-LAK------AYFNNVQQDISREAP 12201
Cdd:COG4913 375 LPASAEEFaalraeAAALLEALEEELEALEEALAEAEAALRDLRRELRELEAEIAsLERrksnipARLLALRDALAEALG 454
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 320544544 12202 Q--------------NPKESEEQLAALRAhLQTLART----EEQLRQ---------LKERHQNSEVAPSVASS-----DD 12249
Cdd:COG4913 455 LdeaelpfvgelievRPEEERWRGAIERV-LGGFALTllvpPEHYAAalrwvnrlhLRGRLVYERVRTGLPDPerprlDP 533
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 320544544 12250 DGILEVLAlwqkiFQDT-FQEYhrLSTRLARSQNssealrlwrqylqhvqsFLSCAIPEDyssLREQQQlcAIHQNLLIS 12328
Cdd:COG4913 534 DSLAGKLD-----FKPHpFRAW--LEAELGRRFD-----------------YVCVDSPEE---LRRHPR--AITRAGQVK 584
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 320544544 12329 QQSVLSETPLESELSEQY-------KALtnlhnETLSRIMQrngELERRVSGWNAYRQQLAALLDWLRQREAERNALQLR 12401
Cdd:COG4913 585 GNGTRHEKDDRRRIRSRYvlgfdnrAKL-----AALEAELA---ELEEELAEAEERLEALEAELDALQERREALQRLAEY 656
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 320544544 12402 YIHLKRVPHLKHRLDAMIQQLDQGEQQSKALQEQQQELARHcdDALATAMRMEQASIGQRISNLRAALKTWQGFLQRVTQ 12481
Cdd:COG4913 657 SWDEIDVASAEREIAELEAELERLDASSDDLAALEEQLEEL--EAELEELEEELDELKGEIGRLEKELEQAEEELDELQD 734
|
570 580 590 600 610 620
....*....|....*....|....*....|....*....|....*....|....*....|
gi 320544544 12482 LSESYEQRVnQLQQEFGAAQKLLDANseslptQPAAIEQLLGSLRAQRVQLGAQVSALES 12541
Cdd:COG4913 735 RLEAAEDLA-RLELRALLEERFAAAL------GDAVERELRENLEERIDALRARLNRAEE 787
|
|
| DUF3584 |
pfam12128 |
Protein of unknown function (DUF3584); This protein is found in bacteria and eukaryotes. ... |
11995-12664 |
2.28e-08 |
|
Protein of unknown function (DUF3584); This protein is found in bacteria and eukaryotes. Proteins in this family are typically between 943 to 1234 amino acids in length. This family contains a P-loop motif suggesting it is a nucleotide binding protein. It may be involved in replication.
Pssm-ID: 432349 [Multi-domain] Cd Length: 1191 Bit Score: 62.55 E-value: 2.28e-08
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 320544544 11995 YERLRKATERLEGLAGDLHNREQLIDELKGAAKPLIEScDVQIVEQIEsAVQEAVVAWNdtsenlQQLRTryqraveLWD 12074
Cdd:pfam12128 233 IAGIMKIRPEFTKLQQEFNTLESAELRLSHLHFGYKSD-ETLIASRQE-ERQETSAELN------QLLRT-------LDD 297
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 320544544 12075 KYRNASAAVKNSIDQQMDAVKSLEQPLDAL--QHAKVCQDNLTTqndrilelrdivakIAADvgLDASALMQGELDALGQ 12152
Cdd:pfam12128 298 QWKEKRDELNGELSAADAAVAKDRSELEALedQHGAFLDADIET--------------AAAD--QEQLPSWQSELENLEE 361
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 320544544 12153 RLaeckDAITTLANVAETQDKERKELDKEVTLAKAYFNNVQQDISREApqnpkeSEEQLAALRAHLQTL-----ARTEEQ 12227
Cdd:pfam12128 362 RL----KALTGKHQDVTAKYNRRRSKIKEQNNRDIAGIKDKLAKIREA------RDRQLAVAEDDLQALeselrEQLEAG 431
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 320544544 12228 LRQLKERHQNSEVAPSVASS--DDDGILEVLALWQKIFQD-----------TFQEYHRLSTRLA----RSQNSSEALRLW 12290
Cdd:pfam12128 432 KLEFNEEEYRLKSRLGELKLrlNQATATPELLLQLENFDErierareeqeaANAEVERLQSELRqarkRRDQASEALRQA 511
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 320544544 12291 RQYLQHVQSFLSCA----IPEDYS---SLREQQQLCAIHQNLLISQQsVLSETPLESELSE-QYKALTNLHNETLsrimq 12362
Cdd:pfam12128 512 SRRLEERQSALDELelqlFPQAGTllhFLRKEAPDWEQSIGKVISPE-LLHRTDLDPEVWDgSVGGELNLYGVKL----- 585
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 320544544 12363 rngELER-RVSGWNAYRQQLAALLDWL---------RQREAERNALQLRyihlKRVPHLKHRLDAMIQQLDQGEQQSKAL 12432
Cdd:pfam12128 586 ---DLKRiDVPEWAASEEELRERLDKAeealqsareKQAAAEEQLVQAN----GELEKASREETFARTALKNARLDLRRL 658
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 320544544 12433 QEQQQELARHCDDALATAMRMEQASIGQRISNLRAALKTWQGFLQRVT-QLSESYEQRVNQLQQEFGAAQklldansesl 12511
Cdd:pfam12128 659 FDEKQSEKDKKNKALAERKDSANERLNSLEAQLKQLDKKHQAWLEEQKeQKREARTEKQAYWQVVEGALD---------- 728
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 320544544 12512 ptqpAAIEQLLGSLRAQRVQLGAQVSALesltvtQEELKECISPHDMKTIRQrnwllwqqhADLDYQLANLINSIEerls 12591
Cdd:pfam12128 729 ----AQLALLKAAIAARRSGAKAELKAL------ETWYKRDLASLGVDPDVI---------AKLKREIRTLERKIE---- 785
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 320544544 12592 llsnyQIRYDR--ISQWLQRLEQR--VEKDADVTAMTNPEQAAKQLEQQV---NSELQLRDKEREWLLSTSRELLTLYSE 12664
Cdd:pfam12128 786 -----RIAVRRqeVLRYFDWYQETwlQRRPRLATQLSNIERAISELQQQLarlIADTKLRRAKLEMERKASEKQQVRLSE 860
|
|
| DUF3584 |
pfam12128 |
Protein of unknown function (DUF3584); This protein is found in bacteria and eukaryotes. ... |
12124-12885 |
5.60e-08 |
|
Protein of unknown function (DUF3584); This protein is found in bacteria and eukaryotes. Proteins in this family are typically between 943 to 1234 amino acids in length. This family contains a P-loop motif suggesting it is a nucleotide binding protein. It may be involved in replication.
Pssm-ID: 432349 [Multi-domain] Cd Length: 1191 Bit Score: 61.01 E-value: 5.60e-08
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 320544544 12124 LRDIVAKIAAD--VGLDASALMQGELDA------LGQRLAECKDAITTLANVAETQDKERKELDkevTLAKAYFNnvqqD 12195
Cdd:pfam12128 198 VKSMIVAILEDdgVVPPKSRLNRQQVEHwirdiqAIAGIMKIRPEFTKLQQEFNTLESAELRLS---HLHFGYKS----D 270
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 320544544 12196 ISREAPQNpKESEEQLAALRAHLQTLartEEQLRQLKERHQNSEVAPSVASSDDDGILEVLALWQKIFQDTfqeyhRLST 12275
Cdd:pfam12128 271 ETLIASRQ-EERQETSAELNQLLRTL---DDQWKEKRDELNGELSAADAAVAKDRSELEALEDQHGAFLDA-----DIET 341
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 320544544 12276 RLARSQNsseaLRLWRQYLQHVQsflscaipedysslreqqqlcAIHQNLLISQQSVLSET-PLESELSEQYKALTNLHN 12354
Cdd:pfam12128 342 AAADQEQ----LPSWQSELENLE---------------------ERLKALTGKHQDVTAKYnRRRSKIKEQNNRDIAGIK 396
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 320544544 12355 ETLSRImqRNGELERRVSGWNAYRQQLAALLDWLRQREAERNALQLRYIhlKRVPHLKHRLDAMIQQLDQGEQQskalqE 12434
Cdd:pfam12128 397 DKLAKI--REARDRQLAVAEDDLQALESELREQLEAGKLEFNEEEYRLK--SRLGELKLRLNQATATPELLLQL-----E 467
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 320544544 12435 QQQELARHCDDALaTAMRMEQASIGQRISNLRAALKTWQGFLQRVtqlsesyEQRVNQLQQEFGAAQKLLDANSES---- 12510
Cdd:pfam12128 468 NFDERIERAREEQ-EAANAEVERLQSELRQARKRRDQASEALRQA-------SRRLEERQSALDELELQLFPQAGTllhf 539
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 320544544 12511 LPTQPAAIEQLLGSL--RAQ--RVQL-----GAQVSALESLTVTQEELKECISP--HDM-KTIRQRNWLL-------WQQ 12571
Cdd:pfam12128 540 LRKEAPDWEQSIGKVisPELlhRTDLdpevwDGSVGGELNLYGVKLDLKRIDVPewAASeEELRERLDKAeealqsaREK 619
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 320544544 12572 HADLDYQLANLINSIEERLSLLSNYQIRYDRISQWLQRL--EQRVEKDADVTAMTNPEQAAKQLEQQVNSELQLRDKE-R 12648
Cdd:pfam12128 620 QAAAEEQLVQANGELEKASREETFARTALKNARLDLRRLfdEKQSEKDKKNKALAERKDSANERLNSLEAQLKQLDKKhQ 699
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 320544544 12649 EWLLSTSRELLTLYSEpevrsqvqqqsdslidRWQRLKYLAKQKATKIGELKMTLLRLEERIAlirAWLFEVESQLDKPL 12728
Cdd:pfam12128 700 AWLEEQKEQKREARTE----------------KQAYWQVVEGALDAQLALLKAAIAARRSGAK---AELKALETWYKRDL 760
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 320544544 12729 NFESYTPNVIEAKLKEHEQIQRSIEHHSSNVGEVLnlvemllndadSWRtqvntsglaasaQNLEQRWKNVCSQSAERKA 12808
Cdd:pfam12128 761 ASLGVDPDVIAKLKREIRTLERKIERIAVRRQEVL-----------RYF------------DWYQETWLQRRPRLATQLS 817
|
730 740 750 760 770 780 790 800
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 320544544 12809 RILT-IWNLLQQLIKLTAEHKNWLGKQESQIAGFERDQ----KSHSKHKLEERQM---ELRAKLEELE-SQSVNLRQLEQ 12879
Cdd:pfam12128 818 NIERaISELQQQLARLIADTKLRRAKLEMERKASEKQQvrlsENLRGLRCEMSKLatlKEDANSEQAQgSIGERLAQLED 897
|
....*.
gi 320544544 12880 IYAKLA 12885
Cdd:pfam12128 898 LKLKRD 903
|
|
| MukB |
COG3096 |
Chromosome condensin MukBEF, ATPase and DNA-binding subunit MukB [Cell cycle control, cell ... |
11881-12654 |
9.07e-08 |
|
Chromosome condensin MukBEF, ATPase and DNA-binding subunit MukB [Cell cycle control, cell division, chromosome partitioning];
Pssm-ID: 442330 [Multi-domain] Cd Length: 1470 Bit Score: 60.74 E-value: 9.07e-08
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 320544544 11881 RQGADVLEKAVADCQAAG--EELVISWQEIMRIRQMLHT---LPMRLKMSVSpvklerDISQLQDDHAF--LESkctniM 11953
Cdd:COG3096 416 QQAVQALEKARALCGLPDltPENAEDYLAAFRAKEQQATeevLELEQKLSVA------DAARRQFEKAYelVCK-----I 484
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 320544544 11954 AILRSRLAVWLRYERQL----ELVHGSVQETDFMMELIRVhgQVDYERLRKATERLEGL----AGDLHNREQLiDELKGA 12025
Cdd:COG3096 485 AGEVERSQAWQTARELLrryrSQQALAQRLQQLRAQLAEL--EQRLRQQQNAERLLEEFcqriGQQLDAAEEL-EELLAE 561
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 320544544 12026 AKPLIESCDVQIVEQIESAVQeavvawndTSENLQQLRTRYQRAVELWDKYRNASAAVKNSIDQQMDAVKSLEQPLDALQ 12105
Cdd:COG3096 562 LEAQLEELEEQAAEAVEQRSE--------LRQQLEQLRARIKELAARAPAWLAAQDALERLREQSGEALADSQEVTAAMQ 633
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 320544544 12106 HAKVCQDNLTTQNDRILELRDIVAKiaadvglDASALMQ--GELDALGQRLAEckdaitTLANV--AETQDkerkeldkE 12181
Cdd:COG3096 634 QLLEREREATVERDELAARKQALES-------QIERLSQpgGAEDPRLLALAE------RLGGVllSEIYD--------D 692
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 320544544 12182 VTLAKA-YFnnvqqdisrEAPQNPKESE---EQLAALRAHLQTLARTEEQLrQLKERHQNS--EVAPSvASSDDDGILEV 12255
Cdd:COG3096 693 VTLEDApYF---------SALYGPARHAivvPDLSAVKEQLAGLEDCPEDL-YLIEGDPDSfdDSVFD-AEELEDAVVVK 761
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 320544544 12256 LAlwqkifqDTFQEYHRLST-----RLARsQNSSEALRLWRQylqhvqsflscAIPEDYSSLR-EQQQLCAIHQNL--LI 12327
Cdd:COG3096 762 LS-------DRQWRYSRFPEvplfgRAAR-EKRLEELRAERD-----------ELAEQYAKASfDVQKLQRLHQAFsqFV 822
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 320544544 12328 SQQ-SVLSETPLESELSEqykaltnlhnetlsrIMQRNGELERRVSGWNAYRQQLAALLDWLRQREAERNALqLRYIHLK 12406
Cdd:COG3096 823 GGHlAVAFAPDPEAELAA---------------LRQRRSELERELAQHRAQEQQLRQQLDQLKEQLQLLNKL-LPQANLL 886
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 320544544 12407 RVPHLKHRLDAMIQQLDQgeqqskaLQEQQQELARHcddalatamrmeqasiGQRISNLRAALKTwqgfLQRVTQLSESY 12486
Cdd:COG3096 887 ADETLADRLEELREELDA-------AQEAQAFIQQH----------------GKALAQLEPLVAV----LQSDPEQFEQL 939
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 320544544 12487 EQRVNQLQQEfgaaQKLLDAnseslptQPAAIEQLLGSLR----AQRVQLGAQVSALesltvtQEELKECISphDMKTIR 12562
Cdd:COG3096 940 QADYLQAKEQ----QRRLKQ-------QIFALSEVVQRRPhfsyEDAVGLLGENSDL------NEKLRARLE--QAEEAR 1000
|
730 740 750 760 770 780 790 800
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 320544544 12563 QRNWLLWQQHADlDYQLANlinsiEERLSLLSNYQIRYdrisQWLQRLEQRVEkDADVTAMTNPEQAAKQLEQQVNSELQ 12642
Cdd:COG3096 1001 REAREQLRQAQA-QYSQYN-----QVLASLKSSRDAKQ----QTLQELEQELE-ELGVQADAEAEERARIRRDELHEELS 1069
|
810
....*....|..
gi 320544544 12643 LRDKEREWLLST 12654
Cdd:COG3096 1070 QNRSRRSQLEKQ 1081
|
|
| YhaN |
COG4717 |
Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown]; |
11930-12426 |
9.69e-08 |
|
Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown];
Pssm-ID: 443752 [Multi-domain] Cd Length: 641 Bit Score: 60.17 E-value: 9.69e-08
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 320544544 11930 KLERDISQLQDDHAFLESKcTNIMAILRSRLAVWLRYERQLElvhgsvQETDFMMELIRVHGqvDYERLRKATERLEGLA 12009
Cdd:COG4717 75 ELEEELKEAEEKEEEYAEL-QEELEELEEELEELEAELEELR------EELEKLEKLLQLLP--LYQELEALEAELAELP 145
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 320544544 12010 GDLHNREQLIDELKGAAKpLIESCDVQIVEQIESAVQEAVVAWNDTSENLQQLRTRYQRAVELWDKYRNASAAVKNSIDQ 12089
Cdd:COG4717 146 ERLEELEERLEELRELEE-ELEELEAELAELQEELEELLEQLSLATEEELQDLAEELEELQQRLAELEEELEEAQEELEE 224
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 320544544 12090 QMDAVKSLEQPLDALQHAKVcqdnlTTQNDRILELRDIVAKIAA-DVGLDASALMQGELDALGQRLAECKDAITTLANVA 12168
Cdd:COG4717 225 LEEELEQLENELEAAALEER-----LKEARLLLLIAAALLALLGlGGSLLSLILTIAGVLFLVLGLLALLFLLLAREKAS 299
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 320544544 12169 ETQDKER-KELDKEVTLAKAYFNNVQQDISREAPQNPKESEE---QLAALRAHLQTLARTEEQLRQLKERHQNSEVAPSV 12244
Cdd:COG4717 300 LGKEAEElQALPALEELEEEELEELLAALGLPPDLSPEELLElldRIEELQELLREAEELEEELQLEELEQEIAALLAEA 379
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 320544544 12245 ASSDDDGILEVLALWQKiFQDTFQEYHRLSTRLARSQNSSEALRLWRQYLQhvqsflscaIPEDYSSLREQQQLcaihqn 12324
Cdd:COG4717 380 GVEDEEELRAALEQAEE-YQELKEELEELEEQLEELLGELEELLEALDEEE---------LEEELEELEEELEE------ 443
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 320544544 12325 llisqqsvlsetpLESELSEQYKALTNLHNETlsRIMQRNGELERRvsgwnayRQQLAALLDWLRQREAERNALQL---- 12400
Cdd:COG4717 444 -------------LEEELEELREELAELEAEL--EQLEEDGELAEL-------LQELEELKAELRELAEEWAALKLalel 501
|
490 500 510
....*....|....*....|....*....|.
gi 320544544 12401 -----RYIHLKRVPHLKHRLDAMIQQLDQGE 12426
Cdd:COG4717 502 leearEEYREERLPPVLERASEYFSRLTDGR 532
|
|
| SMC_prok_B |
TIGR02168 |
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ... |
11996-12649 |
9.88e-08 |
|
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]
Pssm-ID: 274008 [Multi-domain] Cd Length: 1179 Bit Score: 60.46 E-value: 9.88e-08
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 320544544 11996 ERLRKATERLEGLAGDLHNREQLIDELKG---AAKPLIESCDVQI---VEQIESAVQEAVVAwNDTSENLQQLRTRYQRA 12069
Cdd:TIGR02168 260 AELQELEEKLEELRLEVSELEEEIEELQKelyALANEISRLEQQKqilRERLANLERQLEEL-EAQLEELESKLDELAEE 338
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 320544544 12070 VELWDKYRNASAAVKNSIDQQMDAVKSLEQplDALQHAKVCQDNLTTQNDRILELRDIVAKIAADVgldasALMQGELDA 12149
Cdd:TIGR02168 339 LAELEEKLEELKEELESLEAELEELEAELE--ELESRLEELEEQLETLRSKVAQLELQIASLNNEI-----ERLEARLER 411
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 320544544 12150 LGQRLAECKDAITTLANVAETQDKER-----KELDKEVTLAKAYFNNVQ------QDISREAPQNPKESEEQLAALRAHL 12218
Cdd:TIGR02168 412 LEDRRERLQQEIEELLKKLEEAELKElqaelEELEEELEELQEELERLEealeelREELEEAEQALDAAERELAQLQARL 491
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 320544544 12219 QTLARTEEQLRQ--------LKERHQNSEVAPSVAS--------------------------SDDDGILEVLAL-WQKIF 12263
Cdd:TIGR02168 492 DSLERLQENLEGfsegvkalLKNQSGLSGILGVLSElisvdegyeaaieaalggrlqavvveNLNAAKKAIAFLkQNELG 571
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 320544544 12264 QDTFQEYHRLSTRLARSQNssealrlwRQYLQHVQSFLSCAIPEDYSSLREQQQLCAIHQNLLISQqSVLSETPLESELS 12343
Cdd:TIGR02168 572 RVTFLPLDSIKGTEIQGND--------REILKNIEGFLGVAKDLVKFDPKLRKALSYLLGGVLVVD-DLDNALELAKKLR 642
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 320544544 12344 EQYK-------------ALTNLHNETLSRIMQRNGELERrvsgwnaYRQQLAALLDWLRQREAERNAL-QLRYIHLKRVP 12409
Cdd:TIGR02168 643 PGYRivtldgdlvrpggVITGGSAKTNSSILERRREIEE-------LEEKIEELEEKIAELEKALAELrKELEELEEELE 715
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 320544544 12410 HLKHRLDAMIQQLDQGEQQSKALQEQQQELARHCDDALAtamrmEQASIGQRISNLRAALKTWQGFLQRVTQLSESYEQR 12489
Cdd:TIGR02168 716 QLRKELEELSRQISALRKDLARLEAEVEQLEERIAQLSK-----ELTELEAEIEELEERLEEAEEELAEAEAEIEELEAQ 790
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 320544544 12490 VNQLQQEFGAAQKLLDANS-----------------ESLPTQPAAIEQLLGSLRAQRVQLGAQVSAL----ESLTVTQEE 12548
Cdd:TIGR02168 791 IEQLKEELKALREALDELRaeltllneeaanlrerlESLERRIAATERRLEDLEEQIEELSEDIESLaaeiEELEELIEE 870
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 320544544 12549 LKECISPH---------DMKTIRQRNWLLWQQHADLDYQLANLINSIEERLSLLSNYQIRYDRISQWLQRLEQRVEKDAD 12619
Cdd:TIGR02168 871 LESELEALlnerasleeALALLRSELEELSEELRELESKRSELRRELEELREKLAQLELRLEGLEVRIDNLQERLSEEYS 950
|
730 740 750
....*....|....*....|....*....|
gi 320544544 12620 VTAMTNPEQAAKQLEQQVNSELQLRDKERE 12649
Cdd:TIGR02168 951 LTLEEAEALENKIEDDEEEARRRLKRLENK 980
|
|
| YhaN |
COG4717 |
Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown]; |
12381-12885 |
1.07e-07 |
|
Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown];
Pssm-ID: 443752 [Multi-domain] Cd Length: 641 Bit Score: 59.78 E-value: 1.07e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 320544544 12381 LAALLDWLRQREAERNALQLRYIHLKRVPHLKHRLDAMIQQLDQGEQQSKALQEQQQELARhcddalatamrmeqasIGQ 12460
Cdd:COG4717 39 LLAFIRAMLLERLEKEADELFKPQGRKPELNLKELKELEEELKEAEEKEEEYAELQEELEE----------------LEE 102
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 320544544 12461 RISNLRAALKTWQGFLQRVTQLSESYEqrvnqLQQEFGAAQKLLdanseslptqpAAIEQLLGSLRAQRVQLGAQVSALE 12540
Cdd:COG4717 103 ELEELEAELEELREELEKLEKLLQLLP-----LYQELEALEAEL-----------AELPERLEELEERLEELRELEEELE 166
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 320544544 12541 SLTVTQEELKEcisphDMKTIRQRNWLLWQQhadldyQLANLINSIEERLSLLSNYQIRYDRISQWLQRLEQRVEKdadv 12620
Cdd:COG4717 167 ELEAELAELQE-----ELEELLEQLSLATEE------ELQDLAEELEELQQRLAELEEELEEAQEELEELEEELEQ---- 231
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 320544544 12621 tamTNPEQAAKQLEQQVnselqlrDKEREWLLSTSRELLTLYSEPEVRSQVQQQSDSLIDR----WQRLKYLAKQKATKI 12696
Cdd:COG4717 232 ---LENELEAAALEERL-------KEARLLLLIAAALLALLGLGGSLLSLILTIAGVLFLVlgllALLFLLLAREKASLG 301
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 320544544 12697 GELKmTLLRLEERIALIRAWLFEVESQLDKPlnfESYTPNVIEAKLKEHEQIQRsiehhssnvgevlnlvemLLNDADSW 12776
Cdd:COG4717 302 KEAE-ELQALPALEELEEEELEELLAALGLP---PDLSPEELLELLDRIEELQE------------------LLREAEEL 359
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 320544544 12777 RTQVNTSGLAASAQNLeqrWKNVCSQSAERKARILTIWNLLQQLIKLTAEHKNWLgkqESQIAGFERDQKSHSKHKLEER 12856
Cdd:COG4717 360 EEELQLEELEQEIAAL---LAEAGVEDEEELRAALEQAEEYQELKEELEELEEQL---EELLGELEELLEALDEEELEEE 433
|
490 500
....*....|....*....|....*....
gi 320544544 12857 QMELRAKLEELEsqsvnlRQLEQIYAKLA 12885
Cdd:COG4717 434 LEELEEELEELE------EELEELREELA 456
|
|
| PRK11281 |
PRK11281 |
mechanosensitive channel MscK; |
12378-12747 |
2.95e-07 |
|
mechanosensitive channel MscK;
Pssm-ID: 236892 [Multi-domain] Cd Length: 1113 Bit Score: 58.77 E-value: 2.95e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 320544544 12378 RQQLAALLDwLRQREAERNALQ------LRYihLKRVPHLKHRLDAMIQQLDQGEQQskaLQEQQQELARHCDDALATAm 12451
Cdd:PRK11281 42 QAQLDALNK-QKLLEAEDKLVQqdleqtLAL--LDKIDRQKEETEQLKQQLAQAPAK---LRQAQAELEALKDDNDEET- 114
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 320544544 12452 rmeqasiGQRISNLRaalktwqgflqrVTQLsesyEQRVNQLQQEFGAAQK-LLDANSE--SLPTQP----AAIEQllGS 12524
Cdd:PRK11281 115 -------RETLSTLS------------LRQL----ESRLAQTLDQLQNAQNdLAEYNSQlvSLQTQPeraqAALYA--NS 169
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 320544544 12525 LRAQrvQLGAQvsaLESLTVTQEELKEcisphdmktiRQRNWLLWQQHAdLDYQLANLINSIEERLSLLSNYQIRYDRIS 12604
Cdd:PRK11281 170 QRLQ--QIRNL---LKGGKVGGKALRP----------SQRVLLQAEQAL-LNAQNDLQRKSLEGNTQLQDLLQKQRDYLT 233
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 320544544 12605 QWLQRLEQRV--------EKDADVTamtnpEQAAKQLEQQ-----------VNSELQLRDKEREWLLSTSRELLTLySEP 12665
Cdd:PRK11281 234 ARIQRLEHQLqllqeainSKRLTLS-----EKTVQEAQSQdeaariqanplVAQELEINLQLSQRLLKATEKLNTL-TQQ 307
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 320544544 12666 EVRsqVQQQSDSLIDRWQRLKylakqkaTKIGELKMTLL-------------------RLEERIALIRAWLFEVESQLDK 12726
Cdd:PRK11281 308 NLR--VKNWLDRLTQSERNIK-------EQISVLKGSLLlsrilyqqqqalpsadlieGLADRIADLRLEQFEINQQRDA 378
|
410 420
....*....|....*....|.
gi 320544544 12727 PLNFESYtpnvIEAKLKEHEQ 12747
Cdd:PRK11281 379 LFQPDAY----IDKLEAGHKS 395
|
|
| YhaN |
COG4717 |
Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown]; |
12582-13013 |
5.82e-07 |
|
Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown];
Pssm-ID: 443752 [Multi-domain] Cd Length: 641 Bit Score: 57.47 E-value: 5.82e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 320544544 12582 LINSIEERLSLLSNYQIRYDRI-SQWLQRLEQRVEKDADVTAMTNPEQAAKQ-LEQQVNsELQLRDKEREWLLSTSRELL 12659
Cdd:COG4717 47 LLERLEKEADELFKPQGRKPELnLKELKELEEELKEAEEKEEEYAELQEELEeLEEELE-ELEAELEELREELEKLEKLL 125
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 320544544 12660 TLYSEPEVRSQVQQQSDSLIDRWQRLKylakQKATKIGELKMTLLRLEERIAlirawlfEVESQLDKPLNFESytpnviE 12739
Cdd:COG4717 126 QLLPLYQELEALEAELAELPERLEELE----ERLEELRELEEELEELEAELA-------ELQEELEELLEQLS------L 188
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 320544544 12740 AKLKEHEQIQRSIEHHSSNVGEVLNLVEMLLNDADSWRTQVNTSGLAASAQNLEQRWknvcsQSAERKARILT-IWNLLQ 12818
Cdd:COG4717 189 ATEEELQDLAEELEELQQRLAELEEELEEAQEELEELEEELEQLENELEAAALEERL-----KEARLLLLIAAaLLALLG 263
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 320544544 12819 QLIKLTAEHKNWLGKQESQIA----GFERDQKSHSKHKLEERQMELRAKLEELESQsvnlrQLEQIYAKLAMSAGVEPEN 12894
Cdd:COG4717 264 LGGSLLSLILTIAGVLFLVLGllalLFLLLAREKASLGKEAEELQALPALEELEEE-----ELEELLAALGLPPDLSPEE 338
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 320544544 12895 IQKLTLPTKVMVSMWRQLTPRCHALL--DAIDKDAKLMREFN--------------NAQLEATNSLNAIQKALEQLPSAE 12958
Cdd:COG4717 339 LLELLDRIEELQELLREAEELEEELQleELEQEIAALLAEAGvedeeelraaleqaEEYQELKEELEELEEQLEELLGEL 418
|
410 420 430 440 450
....*....|....*....|....*....|....*....|....*....|....*
gi 320544544 12959 NQQTSKAEPKAVLQRLESLEKKLQDAQQHVQQadnlAQEAKTRTKQqpQLKQLLE 13013
Cdd:COG4717 419 EELLEALDEEELEEELEELEEELEELEEELEE----LREELAELEA--ELEQLEE 467
|
|
| SMC_prok_B |
TIGR02168 |
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ... |
12627-13397 |
6.23e-07 |
|
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]
Pssm-ID: 274008 [Multi-domain] Cd Length: 1179 Bit Score: 57.76 E-value: 6.23e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 320544544 12627 EQAAKQLEQQVNS-ELQ---------LRDKEREWLLStsreLLTLysepevrsqvqqQSDSLIDRWQRLKYLAKQKATKI 12696
Cdd:TIGR02168 192 EDILNELERQLKSlERQaekaerykeLKAELRELELA----LLVL------------RLEELREELEELQEELKEAEEEL 255
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 320544544 12697 GELKMTLLRLEERIALIRAWLFEVESQLDKpLNFESYTPNVIEAKLKEHEQIQRSIEHHSSNVGEVLNLVemlLNDADSW 12776
Cdd:TIGR02168 256 EELTAELQELEEKLEELRLEVSELEEEIEE-LQKELYALANEISRLEQQKQILRERLANLERQLEELEAQ---LEELESK 331
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 320544544 12777 RTQVNTSgLAASAQNLEQRWKNVCSQSAERKARILTIWNLLQQLIKLTAEhknwLGKQESQIAGFERDQKSHSKhkleeR 12856
Cdd:TIGR02168 332 LDELAEE-LAELEEKLEELKEELESLEAELEELEAELEELESRLEELEEQ----LETLRSKVAQLELQIASLNN-----E 401
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 320544544 12857 QMELRAKLEELESqsvNLRQLEQIYAKLAMsagvEPENIQKLTLPTKVmvsmwrqltprchALLDAIDKDAKLMREFNNA 12936
Cdd:TIGR02168 402 IERLEARLERLED---RRERLQQEIEELLK----KLEEAELKELQAEL-------------EELEEELEELQEELERLEE 461
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 320544544 12937 QLEatnslnAIQKALEQLPSAenQQTSKAEPKAVLQRLESLEKKLQDAQQHVQQADNLAQEAKTRTKQQPQLKQLLELVS 13016
Cdd:TIGR02168 462 ALE------ELREELEEAEQA--LDAAERELAQLQARLDSLERLQENLEGFSEGVKALLKNQSGLSGILGVLSELISVDE 533
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 320544544 13017 AY-----TTLWQTVQTRIV-TLKTTWLTRAAQA------AASLPVSEAANAAVQVNTLSQRKLRQAQQMQRETSITAKDA 13084
Cdd:TIGR02168 534 GYeaaieAALGGRLQAVVVeNLNAAKKAIAFLKqnelgrVTFLPLDSIKGTEIQGNDREILKNIEGFLGVAKDLVKFDPK 613
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 320544544 13085 Y-------------IMELQTAItECQNNLDELQRTVVDK----------TRKPGpQKIAKLLGNAQSSTELVKHLSHLLL 13141
Cdd:TIGR02168 614 LrkalsyllggvlvVDDLDNAL-ELAKKLRPGYRIVTLDgdlvrpggviTGGSA-KTNSSILERRREIEELEEKIEELEE 691
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 320544544 13142 TECKADDQAAEVDT-VAELTLRFDTLQSQW--KARQQHDQNAS-EVGRLTCPLCTQRNWQQIDNDLWRLEQWLQFAESTQ 13217
Cdd:TIGR02168 692 KIAELEKALAELRKeLEELEEELEQLRKELeeLSRQISALRKDlARLEAEVEQLEERIAQLSKELTELEAEIEELEERLE 771
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 320544544 13218 KAQSAPPSNIELLEDVTQDHREFLLDLESHKSIISSLNvvgdhlATHTLDTEKARQLRSRLEADNERwnnvcINATKwqg 13297
Cdd:TIGR02168 772 EAEEELAEAEAEIEELEAQIEQLKEELKALREALDELR------AELTLLNEEAANLRERLESLERR-----IAATE--- 837
|
730 740 750 760 770 780 790 800
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 320544544 13298 llqtalmgnsefhQTIGELVEWLQRTEQNIKASEPV--DLTEERSVLETKFKKFKDLRAELERCEPRVVSLQDAADQLLR 13375
Cdd:TIGR02168 838 -------------RRLEDLEEQIEELSEDIESLAAEieELEELIEELESELEALLNERASLEEALALLRSELEELSEELR 904
|
810 820
....*....|....*....|..
gi 320544544 13376 SVEGSEQQSQHTYERTLSRLTD 13397
Cdd:TIGR02168 905 ELESKRSELRRELEELREKLAQ 926
|
|
| EnvC |
COG4942 |
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, ... |
12144-12395 |
7.79e-07 |
|
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, cell division, chromosome partitioning];
Pssm-ID: 443969 [Multi-domain] Cd Length: 377 Bit Score: 56.31 E-value: 7.79e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 320544544 12144 QGELDALGQRLAECKDAITTLANVAETQDKERKELDKEVtlakayfNNVQQDIsreapqnpKESEEQLAALRAHLQTLAR 12223
Cdd:COG4942 26 EAELEQLQQEIAELEKELAALKKEEKALLKQLAALERRI-------AALARRI--------RALEQELAALEAELAELEK 90
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 320544544 12224 TEEQLRQLKERHQNsEVAPSVASSDDDGILEVLALwqkifqdtfqeyhrlstrLARSQNSSEALRLwRQYLQHVQSFLSC 12303
Cdd:COG4942 91 EIAELRAELEAQKE-ELAELLRALYRLGRQPPLAL------------------LLSPEDFLDAVRR-LQYLKYLAPARRE 150
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 320544544 12304 AIpedySSLREQQQLCAIHQNLLISQQSVLSEtpLESELSEQYKALTNL---HNETLSRIMQRNGELERRVSGWNAYRQQ 12380
Cdd:COG4942 151 QA----EELRADLAELAALRAELEAERAELEA--LLAELEEERAALEALkaeRQKLLARLEKELAELAAELAELQQEAEE 224
|
250
....*....|....*
gi 320544544 12381 LAALLDWLRQREAER 12395
Cdd:COG4942 225 LEALIARLEAEAAAA 239
|
|
| sbcc |
TIGR00618 |
exonuclease SbcC; All proteins in this family for which functions are known are part of an ... |
11815-12439 |
8.06e-07 |
|
exonuclease SbcC; All proteins in this family for which functions are known are part of an exonuclease complex with sbcD homologs. This complex is involved in the initiation of recombination to regulate the levels of palindromic sequences in DNA. This family is based on the phylogenomic analysis of JA Eisen (1999, Ph.D. Thesis, Stanford University). [DNA metabolism, DNA replication, recombination, and repair]
Pssm-ID: 129705 [Multi-domain] Cd Length: 1042 Bit Score: 57.29 E-value: 8.06e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 320544544 11815 QEPAIEPEKVGELFSLSHKISTQIAEELEGASVLRDQLQAIQEgisnQRKHQAKISVILDECEAAERQGADVLE------ 11888
Cdd:TIGR00618 212 CMPDTYHERKQVLEKELKHLREALQQTQQSHAYLTQKREAQEE----QLKKQQLLKQLRARIEELRAQEAVLEEtqerin 287
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 320544544 11889 ------------KAVADCQAAGEELVISWQEIMRIR-QMLHTLPMRLKMSVSPVKLERDISQLQDDHAFLE---SKCTNI 11952
Cdd:TIGR00618 288 rarkaaplaahiKAVTQIEQQAQRIHTELQSKMRSRaKLLMKRAAHVKQQSSIEEQRRLLQTLHSQEIHIRdahEVATSI 367
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 320544544 11953 MAI------LRSRLAVWLR-YERQLELVHGSVQETDfmmELIRVHGQVDYERLRKATERleglaGDL-HNREQLIDELKG 12024
Cdd:TIGR00618 368 REIscqqhtLTQHIHTLQQqKTTLTQKLQSLCKELD---ILQREQATIDTRTSAFRDLQ-----GQLaHAKKQQELQQRY 439
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 320544544 12025 AA-KPLIESCDVQIVEQIESAVQEAVVAWNDTSENLQQLRTRYQRAVELwdkyRNASAAVKNSI-DQQMDAVKSLEQPLD 12102
Cdd:TIGR00618 440 AElCAAAITCTAQCEKLEKIHLQESAQSLKEREQQLQTKEQIHLQETRK----KAVVLARLLELqEEPCPLCGSCIHPNP 515
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 320544544 12103 ALQHAkvcqDNLTTQNDRILELRDIVAKiaadvGLDASALMQGELDALGQRLAECKDAITTLanvaetqDKERKELDKEV 12182
Cdd:TIGR00618 516 ARQDI----DNPGPLTRRMQRGEQTYAQ-----LETSEEDVYHQLTSERKQRASLKEQMQEI-------QQSFSILTQCD 579
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 320544544 12183 TLAKAYFNNVQQDISREAPQNPKESEEQLaalrahlQTLARTEEQLRQLKERHQNSEVAPSVASSDDDGILEVLAL---- 12258
Cdd:TIGR00618 580 NRSKEDIPNLQNITVRLQDLTEKLSEAED-------MLACEQHALLRKLQPEQDLQDVRLHLQQCSQELALKLTALhalq 652
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 320544544 12259 -----------WQKIFQDTFQEYHRLSTRLARSQNSSEALRLWRQYLQHVQSFLSC--AIPEDYSSLREQQQLCAIHQNL 12325
Cdd:TIGR00618 653 ltltqervrehALSIRVLPKELLASRQLALQKMQSEKEQLTYWKEMLAQCQTLLREleTHIEEYDREFNEIENASSSLGS 732
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 320544544 12326 LISQQSVL---SETPLESELSEQYKALTNLH---NETLSRIMQRNGELERRVSGWNAYRQQLAALLDWLRQREAE----- 12394
Cdd:TIGR00618 733 DLAAREDAlnqSLKELMHQARTVLKARTEAHfnnNEEVTAALQTGAELSHLAAEIQFFNRLREEDTHLLKTLEAEigqei 812
|
650 660 670 680 690 700
....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 320544544 12395 ---------------------RNALQLRYIHLKRVPHLKHRLDAMIQQLDQGEQQSKALQEQQQEL 12439
Cdd:TIGR00618 813 psdedilnlqcetlvqeeeqfLSRLEEKSATLGEITHQLLKYEECSKQLAQLTQEQAKIIQLSDKL 878
|
|
| PRK02224 |
PRK02224 |
DNA double-strand break repair Rad50 ATPase; |
11986-12551 |
1.01e-06 |
|
DNA double-strand break repair Rad50 ATPase;
Pssm-ID: 179385 [Multi-domain] Cd Length: 880 Bit Score: 56.97 E-value: 1.01e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 320544544 11986 LIRVHGQVDYERLRKATERLEGLAGDLHNREQLIDEL----------KGAAKPLIESCD--VQIVEQIESAV---QEAVV 12050
Cdd:PRK02224 189 LDQLKAQIEEKEEKDLHERLNGLESELAELDEEIERYeeqreqaretRDEADEVLEEHEerREELETLEAEIedlRETIA 268
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 320544544 12051 AWNDTSENL-QQLRTRYQRAVELWDKYRNASA------AVKNSIDQQMDAV-KSLEQPLDALQHAKVCQDNLTTQNDRIL 12122
Cdd:PRK02224 269 ETEREREELaEEVRDLRERLEELEEERDDLLAeaglddADAEAVEARREELeDRDEELRDRLEECRVAAQAHNEEAESLR 348
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 320544544 12123 ELRDIVAKIAADvgldasalMQGELDALGQRLAECKDAITTLANVAETQDKERKELDKEVTLAKAYFNNVQqDISREAPQ 12202
Cdd:PRK02224 349 EDADDLEERAEE--------LREEAAELESELEEAREAVEDRREEIEELEEEIEELRERFGDAPVDLGNAE-DFLEELRE 419
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 320544544 12203 NPKESEEQLAALRAHLQTLARTEEQLRQLKER------HQNSEVAPSVASSDDDGilEVLALWQKIFQDTFQEYHRLSTR 12276
Cdd:PRK02224 420 ERDELREREAELEATLRTARERVEEAEALLEAgkcpecGQPVEGSPHVETIEEDR--ERVEELEAELEDLEEEVEEVEER 497
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 320544544 12277 LARSQNSSEALRlwrqylqhvqsflscaipeDYSSLREQ----QQLCAIHQNLLISQQSVLSE-----TPLESELSEQYK 12347
Cdd:PRK02224 498 LERAEDLVEAED-------------------RIERLEERredlEELIAERRETIEEKRERAEElreraAELEAEAEEKRE 558
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 320544544 12348 ALTNLHNETlSRIMQRNGELERRVSGWNAYRQQLAALLDWLRQREAERNALQlryihlkrvpHLKHRLDAMIQQLDQGEQ 12427
Cdd:PRK02224 559 AAAEAEEEA-EEAREEVAELNSKLAELKERIESLERIRTLLAAIADAEDEIE----------RLREKREALAELNDERRE 627
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 320544544 12428 QSKALQEQQQELARHCDDAlatamrmeqasigqRISNLRAALKTWQGFLQRVT-QLSESYEQRvNQLQQEFGAAQKLLDA 12506
Cdd:PRK02224 628 RLAEKRERKRELEAEFDEA--------------RIEEAREDKERAEEYLEQVEeKLDELREER-DDLQAEIGAVENELEE 692
|
570 580 590 600
....*....|....*....|....*....|....*....|....*
gi 320544544 12507 nseslptqpaaieqlLGSLRAQRVQLGAQVSALESLTVTQEELKE 12551
Cdd:PRK02224 693 ---------------LEELRERREALENRVEALEALYDEAEELES 722
|
|
| SMC_prok_B |
TIGR02168 |
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ... |
12389-13111 |
1.81e-06 |
|
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]
Pssm-ID: 274008 [Multi-domain] Cd Length: 1179 Bit Score: 56.22 E-value: 1.81e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 320544544 12389 RQREAERNaLQLRYIHLKRVPHLKHRLDAMIQQLDQGEQQSKALQEQQQELaRHCDDALAT-----------AMRMEQAS 12457
Cdd:TIGR02168 173 RRKETERK-LERTRENLDRLEDILNELERQLKSLERQAEKAERYKELKAEL-RELELALLVlrleelreeleELQEELKE 250
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 320544544 12458 IGQRISNLRAALKTWQGFLQRVTQLSESYEQRVNQLQQEFGAAQKLLDAnsesLPTQPAAIEQLLGSLRAQRVQLGAQVS 12537
Cdd:TIGR02168 251 AEEELEELTAELQELEEKLEELRLEVSELEEEIEELQKELYALANEISR----LEQQKQILRERLANLERQLEELEAQLE 326
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 320544544 12538 ALESltvTQEELKEcisphDMKTIRQRNWLLWQQHADLDYQLANLINSIEERLSLLSNYQIRYDRISQWLQRLEQRVekd 12617
Cdd:TIGR02168 327 ELES---KLDELAE-----ELAELEEKLEELKEELESLEAELEELEAELEELESRLEELEEQLETLRSKVAQLELQI--- 395
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 320544544 12618 advtamtnpEQAAKQLEQQVnSELQLRDKEREWLLSTSRELLTLYSEPEVRsQVQQQSDSLIdrwQRLKYLAKQKATKIG 12697
Cdd:TIGR02168 396 ---------ASLNNEIERLE-ARLERLEDRRERLQQEIEELLKKLEEAELK-ELQAELEELE---EELEELQEELERLEE 461
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 320544544 12698 ELKmtllRLEERIALIRAWLFEVESQLDKpLNFESYtpnVIEAKLKEHEQIQRSI---EHHSSNVGEVLNLVEMLLNDAD 12774
Cdd:TIGR02168 462 ALE----ELREELEEAEQALDAAERELAQ-LQARLD---SLERLQENLEGFSEGVkalLKNQSGLSGILGVLSELISVDE 533
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 320544544 12775 SWRTQVNTSgLAASAQ-----NLEQRWKNVCSQSAERKARILTIWNLLQQLIKLTAEHKNWLGKQEsqiaGFERDQKSHS 12849
Cdd:TIGR02168 534 GYEAAIEAA-LGGRLQavvveNLNAAKKAIAFLKQNELGRVTFLPLDSIKGTEIQGNDREILKNIE----GFLGVAKDLV 608
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 320544544 12850 KHKLEERQ------------------MELRAKLEELESqSVNLrQLEQIYAKLAMSAGVEPENIQKLTLPTKVmvsmwRQ 12911
Cdd:TIGR02168 609 KFDPKLRKalsyllggvlvvddldnaLELAKKLRPGYR-IVTL-DGDLVRPGGVITGGSAKTNSSILERRREI-----EE 681
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 320544544 12912 LTPRCHALLDAIdkdaklmREFNNAQLEATNSLNAIQKALEQLPSAENQQTSK-AEPKAVLQRLESLEKKLQDAQQhvQQ 12990
Cdd:TIGR02168 682 LEEKIEELEEKI-------AELEKALAELRKELEELEEELEQLRKELEELSRQiSALRKDLARLEAEVEQLEERIA--QL 752
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 320544544 12991 ADNLAQEAKTRTKQQPQLKQLLELVSAYTTLWQTVQTRIVTLKTTWLT-----RAAQAAASLPVSEAANAAVQVNTLSQR 13065
Cdd:TIGR02168 753 SKELTELEAEIEELEERLEEAEEELAEAEAEIEELEAQIEQLKEELKAlrealDELRAELTLLNEEAANLRERLESLERR 832
|
730 740 750 760
....*....|....*....|....*....|....*....|....*..
gi 320544544 13066 KLRQAQQMQRETSITAKDAYIME-LQTAITECQNNLDELQRTVVDKT 13111
Cdd:TIGR02168 833 IAATERRLEDLEEQIEELSEDIEsLAAEIEELEELIEELESELEALL 879
|
|
| SPEC |
cd00176 |
Spectrin repeats, found in several proteins involved in cytoskeletal structure; family members ... |
13117-13303 |
2.92e-06 |
|
Spectrin repeats, found in several proteins involved in cytoskeletal structure; family members include spectrin, alpha-actinin and dystrophin; the spectrin repeat forms a three helix bundle with the second helix interrupted by proline in some sequences; the repeats are independent folding units; tandem repeats are found in differing numbers and arrange in an antiparallel manner to form dimers; the repeats are defined by a characteristic tryptophan (W) residue in helix A and a leucine (L) at the carboxyl end of helix C and separated by a linker of 5 residues; two copies of the repeat are present here
Pssm-ID: 238103 [Multi-domain] Cd Length: 213 Bit Score: 52.83 E-value: 2.92e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 320544544 13117 QKIAKLLGNAQSSTELVKHLSHLLLTECKADDQAAEvDTVAELTLRFDTLQSQWKARQQHDQNASEVgrltcplctqrnw 13196
Cdd:cd00176 43 EALEAELAAHEERVEALNELGEQLIEEGHPDAEEIQ-ERLEELNQRWEELRELAEERRQRLEEALDL------------- 108
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 320544544 13197 QQIDNDLWRLEQWLQFAESTQKAQSaPPSNIELLEDVTQDHREFLLDLESHKSIISSLNVVGDHLATHtLDTEKARQLRS 13276
Cdd:cd00176 109 QQFFRDADDLEQWLEEKEAALASED-LGKDLESVEELLKKHKELEEELEAHEPRLKSLNELAEELLEE-GHPDADEEIEE 186
|
170 180
....*....|....*....|....*..
gi 320544544 13277 RLEADNERWNNVCINATKWQGLLQTAL 13303
Cdd:cd00176 187 KLEELNERWEELLELAEERQKKLEEAL 213
|
|
| COG4913 |
COG4913 |
Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown]; |
11836-12236 |
4.87e-06 |
|
Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];
Pssm-ID: 443941 [Multi-domain] Cd Length: 1089 Bit Score: 54.92 E-value: 4.87e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 320544544 11836 TQIAEELEGASVLR-----DQLQAIQEGISNQRKHQAKISVILDECEAAERQ-------GADVLEKAVADCQAAGEELVi 11903
Cdd:COG4913 319 DALREELDELEAQIrgnggDRLEQLEREIERLERELEERERRRARLEALLAAlglplpaSAEEFAALRAEAAALLEALE- 397
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 320544544 11904 swQEIMRIRQMLHTLPMRLKmsvspvKLERDISQLQDDHAFLESKCTNI---MAILRSRLAvwlryeRQLELvhgSVQET 11980
Cdd:COG4913 398 --EELEALEEALAEAEAALR------DLRRELRELEAEIASLERRKSNIparLLALRDALA------EALGL---DEAEL 460
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 320544544 11981 DFMMELIRV---------------HGQ-----VDYERLRKATERLEglagDLHNREQLIDEL--KGAAKPLIESCDVQ-I 12037
Cdd:COG4913 461 PFVGELIEVrpeeerwrgaiervlGGFaltllVPPEHYAAALRWVN----RLHLRGRLVYERvrTGLPDPERPRLDPDsL 536
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 320544544 12038 VEQIESAVQEAVvAWNDTS----------ENLQQLRtRYQRAV-------------ELWDKYRNAS-------------- 12080
Cdd:COG4913 537 AGKLDFKPHPFR-AWLEAElgrrfdyvcvDSPEELR-RHPRAItragqvkgngtrhEKDDRRRIRSryvlgfdnraklaa 614
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 320544544 12081 -----AAVKNSIDQQMDAVKSLEQPLDALQHAKVCQDNLTTQNDRILELRDIVAKIAAdvgLDA--SALMQG--ELDALG 12151
Cdd:COG4913 615 leaelAELEEELAEAEERLEALEAELDALQERREALQRLAEYSWDEIDVASAEREIAE---LEAelERLDASsdDLAALE 691
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 320544544 12152 QRLAECKDAITTLANVAETQDKERKELDKEVTLAKAYFNNVQQDISREAPQNPKESEEQLAALRAHLQTLARTEEQLRQL 12231
Cdd:COG4913 692 EQLEELEAELEELEEELDELKGEIGRLEKELEQAEEELDELQDRLEAAEDLARLELRALLEERFAAALGDAVERELRENL 771
|
....*
gi 320544544 12232 KERHQ 12236
Cdd:COG4913 772 EERID 776
|
|
| MukB |
COG3096 |
Chromosome condensin MukBEF, ATPase and DNA-binding subunit MukB [Cell cycle control, cell ... |
12133-13013 |
5.60e-06 |
|
Chromosome condensin MukBEF, ATPase and DNA-binding subunit MukB [Cell cycle control, cell division, chromosome partitioning];
Pssm-ID: 442330 [Multi-domain] Cd Length: 1470 Bit Score: 54.57 E-value: 5.60e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 320544544 12133 ADVGLDASALMQGELDALGQRLAECKDAITTLANVAETQDKERKELDKEVTLAKAYFNNVQQDIsREApqnpkeseEQLA 12212
Cdd:COG3096 280 RRELSERALELRRELFGARRQLAEEQYRLVEMARELEELSARESDLEQDYQAASDHLNLVQTAL-RQQ--------EKIE 350
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 320544544 12213 ALRAHLQTLA-RTEEQLRQLKERHqnsevapsvassdddgilEVLALWQKIFQDTFQEYHRLSTRLARSQNSSEALRLwR 12291
Cdd:COG3096 351 RYQEDLEELTeRLEEQEEVVEEAA------------------EQLAEAEARLEAAEEEVDSLKSQLADYQQALDVQQT-R 411
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 320544544 12292 --QYLQHVQSflscaipedyssLREQQQLCAI----------HQNLLISQQSVLSETPLESE--LSEQyKALTNLHNETL 12357
Cdd:COG3096 412 aiQYQQAVQA------------LEKARALCGLpdltpenaedYLAAFRAKEQQATEEVLELEqkLSVA-DAARRQFEKAY 478
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 320544544 12358 SRIMQRNGELERRvSGWNAYRQQLAallDWLRQR-EAER-NALQLRYIHLKRVPHLKHRLDAMIQQLDQGEQQS------ 12429
Cdd:COG3096 479 ELVCKIAGEVERS-QAWQTARELLR---RYRSQQaLAQRlQQLRAQLAELEQRLRQQQNAERLLEEFCQRIGQQldaaee 554
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 320544544 12430 -KALQEQQQELARHCDDALATA------MRMEQASIGQRISNLRAALKTWQGFLQRVTQLSEsyeqrvnQLQQEFGAAQK 12502
Cdd:COG3096 555 lEELLAELEAQLEELEEQAAEAveqrseLRQQLEQLRARIKELAARAPAWLAAQDALERLRE-------QSGEALADSQE 627
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 320544544 12503 LLdanseslptqpAAIEQLLGSLRaqrvqlgaQVSALESLTVTQEELKEcisphdmKTIRQrnwlLWQQHADLDYQLanl 12582
Cdd:COG3096 628 VT-----------AAMQQLLERER--------EATVERDELAARKQALE-------SQIER----LSQPGGAEDPRL--- 674
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 320544544 12583 iNSIEERLS--LLSNYqirYDRISqwlqrleqrVEKDADVTAMTNPEQAAkqleqqvnseLQLRDkerewlLSTSRELL- 12659
Cdd:COG3096 675 -LALAERLGgvLLSEI---YDDVT---------LEDAPYFSALYGPARHA----------IVVPD------LSAVKEQLa 725
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 320544544 12660 TLYSEPEVRSQVQQQSDSLIDRWQRLKYLAKQKATKIGELKMTLLRL-----------EERIALIRAWLFEVESQLDKpL 12728
Cdd:COG3096 726 GLEDCPEDLYLIEGDPDSFDDSVFDAEELEDAVVVKLSDRQWRYSRFpevplfgraarEKRLEELRAERDELAEQYAK-A 804
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 320544544 12729 NFESytpnvieaklkehEQIQRSIEHHSSNVGEVLNLV-----EMLLNDADSWRTQVNTSGLAASAQnlEQRWKNVCSQS 12803
Cdd:COG3096 805 SFDV-------------QKLQRLHQAFSQFVGGHLAVAfapdpEAELAALRQRRSELERELAQHRAQ--EQQLRQQLDQL 869
|
730 740 750 760 770 780 790 800
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 320544544 12804 AERkariltiWNLLQQLIKLTAehknwLGKQESqiagferdqkshskhkLEERQMELRAKLEELES-------QSVNLRQ 12876
Cdd:COG3096 870 KEQ-------LQLLNKLLPQAN-----LLADET----------------LADRLEELREELDAAQEaqafiqqHGKALAQ 921
|
810 820 830 840 850 860 870 880
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 320544544 12877 LEQIYAKLAmsagVEPENIQKLTLPTKVMVSMWRQLTPRCHALLDAIDKDAKLMREFNNAQLEATNSLNaiqkalEQLps 12956
Cdd:COG3096 922 LEPLVAVLQ----SDPEQFEQLQADYLQAKEQQRRLKQQIFALSEVVQRRPHFSYEDAVGLLGENSDLN------EKL-- 989
|
890 900 910 920 930
....*....|....*....|....*....|....*....|....*....|....*....
gi 320544544 12957 aeNQQTSKAEpkavLQRLESLEkKLQDAQQHVQQADNLAQEAKT--RTKQQpQLKQLLE 13013
Cdd:COG3096 990 --RARLEQAE----EARREARE-QLRQAQAQYSQYNQVLASLKSsrDAKQQ-TLQELEQ 1040
|
|
| SPEC |
cd00176 |
Spectrin repeats, found in several proteins involved in cytoskeletal structure; family members ... |
12374-12564 |
6.22e-06 |
|
Spectrin repeats, found in several proteins involved in cytoskeletal structure; family members include spectrin, alpha-actinin and dystrophin; the spectrin repeat forms a three helix bundle with the second helix interrupted by proline in some sequences; the repeats are independent folding units; tandem repeats are found in differing numbers and arrange in an antiparallel manner to form dimers; the repeats are defined by a characteristic tryptophan (W) residue in helix A and a leucine (L) at the carboxyl end of helix C and separated by a linker of 5 residues; two copies of the repeat are present here
Pssm-ID: 238103 [Multi-domain] Cd Length: 213 Bit Score: 51.68 E-value: 6.22e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 320544544 12374 WNAYRQQLAALLDWLRqrEAERNALQLRYI-HLKRVPHLKHRLDAMIQQLDQGEQQSKALQEQQQELARHCDDAlATAMR 12452
Cdd:cd00176 2 LQQFLRDADELEAWLS--EKEELLSSTDYGdDLESVEALLKKHEALEAELAAHEERVEALNELGEQLIEEGHPD-AEEIQ 78
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 320544544 12453 MEQASIGQRISNLRAALKTWQGFLQRVTQLSESYEQrVNQLQQEFGAAQKLLdaNSESLPTQPAAIEQLLGSLRAQRVQL 12532
Cdd:cd00176 79 ERLEELNQRWEELRELAEERRQRLEEALDLQQFFRD-ADDLEQWLEEKEAAL--ASEDLGKDLESVEELLKKHKELEEEL 155
|
170 180 190
....*....|....*....|....*....|..
gi 320544544 12533 GAQVSALESLTVTQEELKECISPHDMKTIRQR 12564
Cdd:cd00176 156 EAHEPRLKSLNELAEELLEEGHPDADEEIEEK 187
|
|
| PRK03918 |
PRK03918 |
DNA double-strand break repair ATPase Rad50; |
12410-13011 |
7.56e-06 |
|
DNA double-strand break repair ATPase Rad50;
Pssm-ID: 235175 [Multi-domain] Cd Length: 880 Bit Score: 53.91 E-value: 7.56e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 320544544 12410 HLKHRLDAMIQQLDQGEQQSKALQEQQQELARhcddalatamrmeqasIGQRISNLRAALKTWQGFLQRVTQLSESYEQr 12489
Cdd:PRK03918 173 EIKRRIERLEKFIKRTENIEELIKEKEKELEE----------------VLREINEISSELPELREELEKLEKEVKELEE- 235
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 320544544 12490 vnqLQQEFGAAQKLLdansESLPTQPAAIEQLLGSLRAQRVQLGAQVSALESLTVTQEELKECISPHdMKTIRQRNWLLw 12569
Cdd:PRK03918 236 ---LKEEIEELEKEL----ESLEGSKRKLEEKIRELEERIEELKKEIEELEEKVKELKELKEKAEEY-IKLSEFYEEYL- 306
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 320544544 12570 QQHADLDYQLANL---INSIEERLSLLSNYQIRYDRISQWLQRLEQRVEKdadvtamtnPEQAAKQLEQQVNSELQLRDK 12646
Cdd:PRK03918 307 DELREIEKRLSRLeeeINGIEERIKELEEKEERLEELKKKLKELEKRLEE---------LEERHELYEEAKAKKEELERL 377
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 320544544 12647 EREWLLSTSRELLTLYSEPEVR-SQVQQQSDSLIDRWQRLKYLAKQKATKIGELKMT---------LLRLEERIALIRAW 12716
Cdd:PRK03918 378 KKRLTGLTPEKLEKELEELEKAkEEIEEEISKITARIGELKKEIKELKKAIEELKKAkgkcpvcgrELTEEHRKELLEEY 457
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 320544544 12717 LFEVESqldkplnfesytpnvIEAKLKEHEQIQRSIEhhssnvgEVLNLVEMLLNDADSWRTQVNtsgLAASAQNLEQRW 12796
Cdd:PRK03918 458 TAELKR---------------IEKELKEIEEKERKLR-------KELRELEKVLKKESELIKLKE---LAEQLKELEEKL 512
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 320544544 12797 KNVCSQSAERKARILTiwNLLQQLIKLTAEHKNwLGKQESQIAGFERDQKS--HSKHKLEERQMELRAKLEELESQSVN- 12873
Cdd:PRK03918 513 KKYNLEELEKKAEEYE--KLKEKLIKLKGEIKS-LKKELEKLEELKKKLAEleKKLDELEEELAELLKELEELGFESVEe 589
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 320544544 12874 ----LRQLEQIYAKLAMSAGVEPEniqkltlptkvmvsmWRQLTPRCHALLDAIDKDAKLMREFNNAQLEATNSLNAIQK 12949
Cdd:PRK03918 590 leerLKELEPFYNEYLELKDAEKE---------------LEREEKELKKLEEELDKAFEELAETEKRLEELRKELEELEK 654
|
570 580 590 600 610 620
....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 320544544 12950 AL--EQLPSAENQQTSKA-EPKAVLQRLESLEKKLQDAQqhvQQADNLAQEAKTRTKQQPQLKQL 13011
Cdd:PRK03918 655 KYseEEYEELREEYLELSrELAGLRAELEELEKRREEIK---KTLEKLKEELEEREKAKKELEKL 716
|
|
| PRK10246 |
PRK10246 |
exonuclease subunit SbcC; Provisional |
12039-12445 |
8.66e-06 |
|
exonuclease subunit SbcC; Provisional
Pssm-ID: 182330 [Multi-domain] Cd Length: 1047 Bit Score: 54.04 E-value: 8.66e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 320544544 12039 EQIESAVQEAVVAWNDTSENLQQLRTRYqravelwdKYRNASAAVKNSIDQQMDAVKSLEQPLDALQHAKVCQDNLTTQN 12118
Cdd:PRK10246 443 AQLQVAIQNVTQEQTQRNAALNEMRQRY--------KEKTQQLADVKTICEQEARIKDLEAQRAQLQAGQPCPLCGSTSH 514
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 320544544 12119 DRI-----LEL------RDIVAKIAADVGlDASALMQGELDALGQRLAECKDAITTLANVAETQDKERKEL--DKEVTLa 12185
Cdd:PRK10246 515 PAVeayqaLEPgvnqsrLDALEKEVKKLG-EEGAALRGQLDALTKQLQRDESEAQSLRQEEQALTQQWQAVcaSLNITL- 592
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 320544544 12186 kayfnNVQQDIsreAP--QNPKESEEQL----------AALRAHLQTLARTEEQL--RQLKERHQNSEVAPSVASSDDDg 12251
Cdd:PRK10246 593 -----QPQDDI---QPwlDAQEEHERQLrllsqrhelqGQIAAHNQQIIQYQQQIeqRQQQLLTALAGYALTLPQEDEE- 663
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 320544544 12252 ilevlALWQKIFQDTFQEYHRLSTRLARSQNSSEALRLWRQYLQHVQSFLSCAIPEDYSSLREQQQLC-AIHQNLLISQQ 12330
Cdd:PRK10246 664 -----ASWLATRQQEAQSWQQRQNELTALQNRIQQLTPLLETLPQSDDLPHSEETVALDNWRQVHEQClSLHSQLQTLQQ 738
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 320544544 12331 SVLSETPLESELSEQYK-ALTN-------------LHNETLSRIMQRNGELERRvsgwnayRQQLAALLDWLRQREAERN 12396
Cdd:PRK10246 739 QDVLEAQRLQKAQAQFDtALQAsvfddqqaflaalLDEETLTQLEQLKQNLENQ-------RQQAQTLVTQTAQALAQHQ 811
|
410 420 430 440 450 460
....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 320544544 12397 ALQLRYIHLK-RVPHLKHRLDAMIQQL-----DQGE------------QQSKALQEQQQELARHCDD 12445
Cdd:PRK10246 812 QHRPDGLDLTvTVEQIQQELAQLAQQLrenttRQGEirqqlkqdadnrQQQQALMQQIAQATQQVED 878
|
|
| COG4995 |
COG4995 |
Uncharacterized conserved protein, contains CHAT domain [Function unknown]; |
12164-12608 |
1.19e-05 |
|
Uncharacterized conserved protein, contains CHAT domain [Function unknown];
Pssm-ID: 444019 [Multi-domain] Cd Length: 711 Bit Score: 53.43 E-value: 1.19e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 320544544 12164 LANVAETQDKERKELDKEVTLAKAYFNNVQQDISREAPQNPKESEEQLAALRAHLQTLARTEEQLRQLKERHQNSEVAPS 12243
Cdd:COG4995 8 ALLAALLAALALALLALALLLLLAALAAAALLLLALLALLLALAAAAAAALAAAALALALLAAAALALLLLALALAALAL 87
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 320544544 12244 VASSDDDGILEVLALWQKIFQDTFQEYHRLSTRLARSQNSSEALRLWRQYLQHVQSFLSCAIPEDYSSLREQQQLCAIHQ 12323
Cdd:COG4995 88 ALLAAALALALAAAALAALALLAALLALAAAAALLALLAALALLALLAALAAALAAAAAAALAAALAAAAAAAAAAALLA 167
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 320544544 12324 NLLISQQSVLSETPLESELSEQYKALTNLHNETLSRIMQRNGELERRVSGWNAYRQQLAALLDWLRQREAERNALQLRyi 12403
Cdd:COG4995 168 LALALAAAALALLALLLAALAAALAAAAAALALLLALLLLAALAAALAAALAALLLALLALAAALLALLLLALLALAA-- 245
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 320544544 12404 hlkrvphLKHRLDAMIQQLDQGEQQSKALQEQQQELARHCDDALATAMRMEQASIGQRISNLRAALKTWQGFLQRVTQLS 12483
Cdd:COG4995 246 -------AAAALAAAAAALLALAAALLLLAALAALAAAAAAAALAALALAAALALAAAALALALLLAAAAAAALAALALL 318
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 320544544 12484 ESYEQRVNQLQQEFGAAQKLLDANSESLPTQPAAIEQLLGSLRAQRVQLGAQVSALESLTVTQEELKECISPHDMKTIRQ 12563
Cdd:COG4995 319 LLAALLLLLAALALLALLLLLAAAALLAAALAAALALAAALALALLAALLLLLAALLALLLEALLLLLLALLAALLLLAA 398
|
410 420 430 440 450
....*....|....*....|....*....|....*....|....*....|..
gi 320544544 12564 RNWLLWQQHADLDYQLANLI-------NSIEERLSLLSNYQIRYDRISQWLQ 12608
Cdd:COG4995 399 ALLALAAAQLLRLLLAALALllalaayAAARLALLALIEYIILPDRLYAFVQ 450
|
|
| Smc |
COG1196 |
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ... |
11848-12470 |
1.27e-05 |
|
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];
Pssm-ID: 440809 [Multi-domain] Cd Length: 983 Bit Score: 53.40 E-value: 1.27e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 320544544 11848 LRDQLQAIQEGISNQRKHQAKISVILDECEAAERQGADVLEKAVADCQAAGEELVISWQEIMRirqmlhtlpmrlkmsvs 11927
Cdd:COG1196 237 LEAELEELEAELEELEAELEELEAELAELEAELEELRLELEELELELEEAQAEEYELLAELAR----------------- 299
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 320544544 11928 pvkLERDISQLQDDHAFLESKctniMAILRSRLAVWlryERQLELVHGSVQETDfmmelirvhgqvdyERLRKATERLEG 12007
Cdd:COG1196 300 ---LEQDIARLEERRRELEER----LEELEEELAEL---EEELEELEEELEELE--------------EELEEAEEELEE 355
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 320544544 12008 LAGDLHNREQLIDELKGAAKPLIEScdvqiVEQIESAVQEAVVAWNDTSENLQQLRTRYQRAVELWDKYRNASAAVKNSI 12087
Cdd:COG1196 356 AEAELAEAEEALLEAEAELAEAEEE-----LEELAEELLEALRAAAELAAQLEELEEAEEALLERLERLEEELEELEEAL 430
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 320544544 12088 DQQMDAVKSLEQPLDALQHAKVCQDNLTTQNDRIL-----ELRDIVAKIAADVGLDASALMQGELDALGQRLAECKDAIT 12162
Cdd:COG1196 431 AELEEEEEEEEEALEEAAEEEAELEEEEEALLELLaelleEAALLEAALAELLEELAEAAARLLLLLEAEADYEGFLEGV 510
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 320544544 12163 TLANVAETQDKERKELDKEVTLAKAYFNNVQQDISREAPQNPKESEEQLAALRAHLQTL---ARTEEQLRQLKERHQNSE 12239
Cdd:COG1196 511 KAALLLAGLRGLAGAVAVLIGVEAAYEAALEAALAAALQNIVVEDDEVAAAAIEYLKAAkagRATFLPLDKIRARAALAA 590
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 320544544 12240 VAPSVASSDDDGILEVLALWQKIFQDTFQEYHRLSTRLARSQNSSEALRlwrqylqhvqsflscaipedysslreqqqlc 12319
Cdd:COG1196 591 ALARGAIGAAVDLVASDLREADARYYVLGDTLLGRTLVAARLEAALRRA------------------------------- 639
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 320544544 12320 aihQNLLISQQSVLSETPLESELSEQYKALTNLHNETLSRIMQRNGELERRVSgwnayRQQLAALLDWLRQREAERNALQ 12399
Cdd:COG1196 640 ---VTLAGRLREVTLEGEGGSAGGSLTGGSRRELLAALLEAEAELEELAERLA-----EEELELEEALLAEEEEERELAE 711
|
570 580 590 600 610 620 630
....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 320544544 12400 LRyihlKRVPHLKHRLDAMIQQLDQGEQQSKALQEQQQELARHcDDALATAMRMEQASIGQRISNLRAALK 12470
Cdd:COG1196 712 AE----EERLEEELEEEALEEQLEAEREELLEELLEEEELLEE-EALEELPEPPDLEELERELERLEREIE 777
|
|
| YhaN |
COG4717 |
Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown]; |
12817-13241 |
1.47e-05 |
|
Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown];
Pssm-ID: 443752 [Multi-domain] Cd Length: 641 Bit Score: 52.85 E-value: 1.47e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 320544544 12817 LQQLIKLTAEhknwLGKQESQIAGFERDQKShsKHKLEERQMELRAKLEELESQSVNLRQLEQIYAKLAMSAGVEPEniq 12896
Cdd:COG4717 70 LKELKELEEE----LKEAEEKEEEYAELQEE--LEELEEELEELEAELEELREELEKLEKLLQLLPLYQELEALEAE--- 140
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 320544544 12897 kltlptkvmvsmWRQLTPRCHALLDAIDKDAKLMREFNNAQLEATNSLNAIQKALEQLPSAENQ--QTSKAEPKAVLQRL 12974
Cdd:COG4717 141 ------------LAELPERLEELEERLEELRELEEELEELEAELAELQEELEELLEQLSLATEEelQDLAEELEELQQRL 208
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 320544544 12975 ESLEKKLQDAQQHVQQADN---LAQEAKTRTKQQPQLKQ----------LLELVSAYTTLWQTVQTR---------IVTL 13032
Cdd:COG4717 209 AELEEELEEAQEELEELEEeleQLENELEAAALEERLKEarlllliaaaLLALLGLGGSLLSLILTIagvlflvlgLLAL 288
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 320544544 13033 KTTWLTRAAQAAASLpvSEAANAAVQVNTLSQRKLRQAQQmQRETSITAKDAYIMELQTAITECQNNLDELQRTVVDKTR 13112
Cdd:COG4717 289 LFLLLAREKASLGKE--AEELQALPALEELEEEELEELLA-ALGLPPDLSPEELLELLDRIEELQELLREAEELEEELQL 365
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 320544544 13113 KPGPQKIAKLLGNAQSSTE------------------LVKHLSHLLLTECKADDQAAEVDTVAELTLRFDTLQSQWKA-R 13173
Cdd:COG4717 366 EELEQEIAALLAEAGVEDEeelraaleqaeeyqelkeELEELEEQLEELLGELEELLEALDEEELEEELEELEEELEElE 445
|
410 420 430 440 450 460 470
....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 320544544 13174 QQHDQNASEVGRLTcplctqrnwQQI-----DNDLWRLEQWLQFAESTQKAQSAPPSNIELLEDVTQDHREFL 13241
Cdd:COG4717 446 EELEELREELAELE---------AELeqleeDGELAELLQELEELKAELRELAEEWAALKLALELLEEAREEY 509
|
|
| YhaN |
COG4717 |
Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown]; |
11759-12230 |
1.99e-05 |
|
Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown];
Pssm-ID: 443752 [Multi-domain] Cd Length: 641 Bit Score: 52.46 E-value: 1.99e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 320544544 11759 EKLKMVERELQEIYLTMTSMKGVIKNEEELclyIERVQVLRTRVGFIGNELGRIGLQEpaiepeKVGELFSLSHKISTQI 11838
Cdd:COG4717 71 KELKELEEELKEAEEKEEEYAELQEELEEL---EEELEELEAELEELREELEKLEKLL------QLLPLYQELEALEAEL 141
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 320544544 11839 AEELEGASVLRDQLQAIQEGISNQRKHQAKISVILDECEAAERQGADVLEKAVADCQAAGEELvisWQEIMRIRQMLHTL 11918
Cdd:COG4717 142 AELPERLEELEERLEELRELEEELEELEAELAELQEELEELLEQLSLATEEELQDLAEELEEL---QQRLAELEEELEEA 218
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 320544544 11919 PMRLKmsvspvKLERDISQLQDDHAFLESKCT--------NIMAILRSRLAVWLRYERQLELVHGSVQETDFMMELIRVH 11990
Cdd:COG4717 219 QEELE------ELEEELEQLENELEAAALEERlkearlllLIAAALLALLGLGGSLLSLILTIAGVLFLVLGLLALLFLL 292
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 320544544 11991 GQVDYERLRKATERLEGLAGDLHNREQLIDELKgAAKPLIESCDVQIVEQIESAVQEAVVAWNDTSENLQQLRT--RYQR 12068
Cdd:COG4717 293 LAREKASLGKEAEELQALPALEELEEEELEELL-AALGLPPDLSPEELLELLDRIEELQELLREAEELEEELQLeeLEQE 371
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 320544544 12069 AVELWDKYrnasaavknsidqQMDAVKSLEQPLDALQHAKVCQDNLTTQNDRILELRDIVAKIAADVGLDAsalMQGELD 12148
Cdd:COG4717 372 IAALLAEA-------------GVEDEEELRAALEQAEEYQELKEELEELEEQLEELLGELEELLEALDEEE---LEEELE 435
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 320544544 12149 ALGQRLAECKDAITTLANVAETQDKERKELDKEVTLAKAY--FNNVQQDISREApqnpkeseEQLAALRAHLQTLARTEE 12226
Cdd:COG4717 436 ELEEELEELEEELEELREELAELEAELEQLEEDGELAELLqeLEELKAELRELA--------EEWAALKLALELLEEARE 507
|
....
gi 320544544 12227 QLRQ 12230
Cdd:COG4717 508 EYRE 511
|
|
| EnvC |
COG4942 |
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, ... |
12338-12589 |
2.53e-05 |
|
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, cell division, chromosome partitioning];
Pssm-ID: 443969 [Multi-domain] Cd Length: 377 Bit Score: 51.69 E-value: 2.53e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 320544544 12338 LESELSEQYKALTNLhNETLSRIMQRNGELERRVsgwNAYRQQLAALLDWLRQREAERNALQLryihlkrvphlkhRLDA 12417
Cdd:COG4942 25 AEAELEQLQQEIAEL-EKELAALKKEEKALLKQL---AALERRIAALARRIRALEQELAALEA-------------ELAE 87
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 320544544 12418 MIQQLDQGEQQskaLQEQQQELARHcddaLATAMRMEQASIGQRISNLRAALKtwqgfLQRVTQLSESYEQRVNQLQQEF 12497
Cdd:COG4942 88 LEKEIAELRAE---LEAQKEELAEL----LRALYRLGRQPPLALLLSPEDFLD-----AVRRLQYLKYLAPARREQAEEL 155
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 320544544 12498 GAAQKLLDANSESLPTQPAAIEQLLGSLRAQRVQLGAQVSALESLtvtQEELKEcisphDMKTIRQRNWLLWQQHADLDY 12577
Cdd:COG4942 156 RADLAELAALRAELEAERAELEALLAELEEERAALEALKAERQKL---LARLEK-----ELAELAAELAELQQEAEELEA 227
|
250
....*....|..
gi 320544544 12578 QLANLINSIEER 12589
Cdd:COG4942 228 LIARLEAEAAAA 239
|
|
| EnvC |
COG4942 |
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, ... |
12658-12903 |
4.56e-05 |
|
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, cell division, chromosome partitioning];
Pssm-ID: 443969 [Multi-domain] Cd Length: 377 Bit Score: 50.92 E-value: 4.56e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 320544544 12658 LLTLYSEPEVRSQVQQQSDSLIDRWQRLKYLAKQKATKIGELKMTLLRLEERIALIRAWLFEVESQLdkplnfesytpNV 12737
Cdd:COG4942 12 ALAAAAQADAAAEAEAELEQLQQEIAELEKELAALKKEEKALLKQLAALERRIAALARRIRALEQEL-----------AA 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 320544544 12738 IEAKL----KEHEQIQRSIEHHSSNVGEVL---------NLVEMLLNDADSWRTQVNTSGLAASAQNLEQRWKNVCSQSA 12804
Cdd:COG4942 81 LEAELaeleKEIAELRAELEAQKEELAELLralyrlgrqPPLALLLSPEDFLDAVRRLQYLKYLAPARREQAEELRADLA 160
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 320544544 12805 ERKARILTIWNLLQQLIKLTAEhknwlgkQESQIAGFERDQKSHSK--HKLEERQMELRAKLEELESQSVNLRQL----- 12877
Cdd:COG4942 161 ELAALRAELEAERAELEALLAE-------LEEERAALEALKAERQKllARLEKELAELAAELAELQQEAEELEALiarle 233
|
250 260
....*....|....*....|....*..
gi 320544544 12878 -EQIYAKLAMSAGVEPENIQKLTLPTK 12903
Cdd:COG4942 234 aEAAAAAERTPAAGFAALKGKLPWPVS 260
|
|
| SPEC |
cd00176 |
Spectrin repeats, found in several proteins involved in cytoskeletal structure; family members ... |
9546-9732 |
5.30e-05 |
|
Spectrin repeats, found in several proteins involved in cytoskeletal structure; family members include spectrin, alpha-actinin and dystrophin; the spectrin repeat forms a three helix bundle with the second helix interrupted by proline in some sequences; the repeats are independent folding units; tandem repeats are found in differing numbers and arrange in an antiparallel manner to form dimers; the repeats are defined by a characteristic tryptophan (W) residue in helix A and a leucine (L) at the carboxyl end of helix C and separated by a linker of 5 residues; two copies of the repeat are present here
Pssm-ID: 238103 [Multi-domain] Cd Length: 213 Bit Score: 48.98 E-value: 5.30e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 320544544 9546 QELDELLQSLSSVEDGIANMN----QSSLDGMLHGLKLIQSNLEVHERDAIELKNQAKKL-----PTDPATERLLNDTVD 9616
Cdd:cd00176 7 RDADELEAWLSEKEELLSSTDygddLESVEALLKKHEALEAELAAHEERVEALNELGEQLieeghPDAEEIQERLEELNQ 86
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 320544544 9617 RIDLLLRRTQQgitmIANAMHGQKKRQQeideYQQHLLELEQWIIEVSAELASfeptSDSSTDEQVLKSQVERSQQLLRT 9696
Cdd:cd00176 87 RWEELRELAEE----RRQRLEEALDLQQ----FFRDADDLEQWLEEKEAALAS----EDLGKDLESVEELLKKHKELEEE 154
|
170 180 190
....*....|....*....|....*....|....*...
gi 320544544 9697 LKDRQQSMEDLVEQTRQL--QSHPDVSPLADTLMEQLQ 9732
Cdd:cd00176 155 LEAHEPRLKSLNELAEELleEGHPDADEEIEEKLEELN 192
|
|
| rad50 |
TIGR00606 |
rad50; All proteins in this family for which functions are known are involvedin recombination, ... |
12041-12794 |
6.39e-05 |
|
rad50; All proteins in this family for which functions are known are involvedin recombination, recombinational repair, and/or non-homologous end joining.They are components of an exonuclease complex with MRE11 homologs. This family is distantly related to the SbcC family of bacterial proteins.This family is based on the phylogenomic analysis of JA Eisen (1999, Ph.D. Thesis, Stanford University).
Pssm-ID: 129694 [Multi-domain] Cd Length: 1311 Bit Score: 51.20 E-value: 6.39e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 320544544 12041 IESAVQEAVVAWNDTSENLQQLRTRYQRAVELWDKYRNASAAVKNSIDQqmdavksLEQPLDALQHAKVCQDNLTTQNDR 12120
Cdd:TIGR00606 400 IERQEDEAKTAAQLCADLQSKERLKQEQADEIRDEKKGLGRTIELKKEI-------LEKKQEELKFVIKELQQLEGSSDR 472
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 320544544 12121 ILELRDIVAKIAADVG-LDASALM-------------QGELD----ALGQRLAECKDAITTLanvAETQDKERKELDK-- 12180
Cdd:TIGR00606 473 ILELDQELRKAERELSkAEKNSLTetlkkevkslqneKADLDrklrKLDQEMEQLNHHTTTR---TQMEMLTKDKMDKde 549
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 320544544 12181 -----------EVTLAKAYFNNVQQ--DISREAPQNPKESEEQLAALRAHLQTLARTEEQLRQLKERHQNSEvapsvaSS 12247
Cdd:TIGR00606 550 qirkiksrhsdELTSLLGYFPNKKQleDWLHSKSKEINQTRDRLAKLNKELASLEQNKNHINNELESKEEQL------SS 623
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 320544544 12248 DDDGILEVLALwqkifQDTFQEYHRLSTRLARSQNS----SEALRLWRQYLQHVQSFLSCAIP---EDYSSLREQQQLCA 12320
Cdd:TIGR00606 624 YEDKLFDVCGS-----QDEESDLERLKEEIEKSSKQramlAGATAVYSQFITQLTDENQSCCPvcqRVFQTEAELQEFIS 698
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 320544544 12321 IHQNLLISQQSVLSETplESELSEQYKAltnlHNETLSRIMQRNGELERRVsgwnayrqqlaalldwlrqreaernalql 12400
Cdd:TIGR00606 699 DLQSKLRLAPDKLKST--ESELKKKEKR----RDEMLGLAPGRQSIIDLKE----------------------------- 743
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 320544544 12401 ryihlKRVPHLKHRLDAM---IQQLDQG-EQQSKALQE--QQQELARHC--DDALATAMRMEQASIGQRISNLRAALKTW 12472
Cdd:TIGR00606 744 -----KEIPELRNKLQKVnrdIQRLKNDiEEQETLLGTimPEEESAKVCltDVTIMERFQMELKDVERKIAQQAAKLQGS 818
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 320544544 12473 QGFL--QRVTQLSESYEQRVNQLQQEFGAAQKLLDANSEslptQPAAIEQLLGSLRAQRVQLG---AQVSALESLTVTQ- 12546
Cdd:TIGR00606 819 DLDRtvQQVNQEKQEKQHELDTVVSKIELNRKLIQDQQE----QIQHLKSKTNELKSEKLQIGtnlQRRQQFEEQLVELs 894
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 320544544 12547 EELKECISphDMKTIRQRNWLLWQQHADLDYQLANLINSIEERLSL----LSNYQIRYDRISQWLQRLEQRVEKDADVTA 12622
Cdd:TIGR00606 895 TEVQSLIR--EIKDAKEQDSPLETFLEKDQQEKEELISSKETSNKKaqdkVNDIKEKVKNIHGYMKDIENKIQDGKDDYL 972
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 320544544 12623 MTNPEQAAKqleqqVNSELQLRDKEREWLLSTSRELLTLYSEPEVRSQVQQQSDSLIDRWQRLKYLAKQKATKIGEL--- 12699
Cdd:TIGR00606 973 KQKETELNT-----VNAQLEECEKHQEKINEDMRLMRQDIDTQKIQERWLQDNLTLRKRENELKEVEEELKQHLKEMgqm 1047
|
730 740 750 760 770 780 790 800
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 320544544 12700 -----KMTLLRLEERIALIRAWLFEVESQLdkplnfESYTPNVIEAKLKEHEQIQRSIEHHSSNVGEVLNLVEMLLNDAD 12774
Cdd:TIGR00606 1048 qvlqmKQEHQKLEENIDLIKRNHVLALGRQ------KGYEKEIKHFKKELREPQFRDAEEKYREMMIVMRTTELVNKDLD 1121
|
810 820
....*....|....*....|
gi 320544544 12775 SWRTQVNTSGLAASAQNLEQ 12794
Cdd:TIGR00606 1122 IYYKTLDQAIMKFHSMKMEE 1141
|
|
| COG4913 |
COG4913 |
Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown]; |
12174-12731 |
7.31e-05 |
|
Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];
Pssm-ID: 443941 [Multi-domain] Cd Length: 1089 Bit Score: 51.07 E-value: 7.31e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 320544544 12174 ERKELDKEVTLAKAYFNNVQQdiSREAPQNPKESEEQLAALRAHLQTLARTEEQLRQLkerhqnsevapsvassddDGIL 12253
Cdd:COG4913 219 EEPDTFEAADALVEHFDDLER--AHEALEDAREQIELLEPIRELAERYAAARERLAEL------------------EYLR 278
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 320544544 12254 EVLALWQKifqdtFQEYHRLSTRLARSQnssealrlwrqylqhvqsflscaipEDYSSLREQQqlcaihqnllisqqsvl 12333
Cdd:COG4913 279 AALRLWFA-----QRRLELLEAELEELR-------------------------AELARLEAEL----------------- 311
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 320544544 12334 setpleSELSEQYKALTNLHNETLSRIMQRNGELErrvsgwnayrQQLAALLDWLRQREAERNALQLRYIHLKRVPHLKH 12413
Cdd:COG4913 312 ------ERLEARLDALREELDELEAQIRGNGGDRL----------EQLEREIERLERELEERERRRARLEALLAALGLPL 375
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 320544544 12414 RLDAmiqqldqgeqqsKALQEQQQELARHCDDALATAMRMEQA--SIGQRISNLRAALKTWQGFLQRVTQLSESYEQRV- 12490
Cdd:COG4913 376 PASA------------EEFAALRAEAAALLEALEEELEALEEAlaEAEAALRDLRRELRELEAEIASLERRKSNIPARLl 443
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 320544544 12491 ---NQLQQEFGAAQK-------LLDANSESLPTQPaAIEQLLGSLR----------AQ------RVQLGAQV-------- 12536
Cdd:COG4913 444 alrDALAEALGLDEAelpfvgeLIEVRPEEERWRG-AIERVLGGFAltllvppehyAAalrwvnRLHLRGRLvyervrtg 522
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 320544544 12537 ------------SALESLTV-----------------------TQEELKEC---ISP------------HDMKTIRQRNW 12566
Cdd:COG4913 523 lpdperprldpdSLAGKLDFkphpfrawleaelgrrfdyvcvdSPEELRRHpraITRagqvkgngtrheKDDRRRIRSRY 602
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 320544544 12567 LL-W---QQHADLDYQLANL---INSIEERLSLLSNYQIRYDRISQWLQRLEQRVEKDADVtamtnpEQAAKQLEQQvns 12639
Cdd:COG4913 603 VLgFdnrAKLAALEAELAELeeeLAEAEERLEALEAELDALQERREALQRLAEYSWDEIDV------ASAEREIAEL--- 673
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 320544544 12640 elqlrDKEREWLLSTSRELLTLYSEpevRSQVQQQSDSLIDRWQRLKylakqkaTKIGELKMTLLRLEERIALIRAWLFE 12719
Cdd:COG4913 674 -----EAELERLDASSDDLAALEEQ---LEELEAELEELEEELDELK-------GEIGRLEKELEQAEEELDELQDRLEA 738
|
650
....*....|..
gi 320544544 12720 VESQLDKPLNFE 12731
Cdd:COG4913 739 AEDLARLELRAL 750
|
|
| PRK11281 |
PRK11281 |
mechanosensitive channel MscK; |
12315-12612 |
7.62e-05 |
|
mechanosensitive channel MscK;
Pssm-ID: 236892 [Multi-domain] Cd Length: 1113 Bit Score: 50.68 E-value: 7.62e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 320544544 12315 QQQLCAIHQNLLISQQSVLSETPLESELseqykaltnlhnETLSRIMQRNGELErrvsgwnAYRQQLAALLDWLRQREAE 12394
Cdd:PRK11281 42 QAQLDALNKQKLLEAEDKLVQQDLEQTL------------ALLDKIDRQKEETE-------QLKQQLAQAPAKLRQAQAE 102
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 320544544 12395 RNALQLryihlKRVPHLKHRLDAM-IQQL-DQGEQQSKALQEQQQELARHCDDALATAMRME--QASIG---QRISNLRA 12467
Cdd:PRK11281 103 LEALKD-----DNDEETRETLSTLsLRQLeSRLAQTLDQLQNAQNDLAEYNSQLVSLQTQPEraQAALYansQRLQQIRN 177
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 320544544 12468 ALKTwqgflQRVTQLSESYEQRvNQLQQEfgaaQKLLDANSESLPTQPAAIEQLLGSLRAQRVQLGAQVSALES------ 12541
Cdd:PRK11281 178 LLKG-----GKVGGKALRPSQR-VLLQAE----QALLNAQNDLQRKSLEGNTQLQDLLQKQRDYLTARIQRLEHqlqllq 247
|
250 260 270 280 290 300 310
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 320544544 12542 -------LTVTQEELKECISPHDMKTIrQRNWLLwQQHADLDYQLAN-LINSIeERLSLLSNYQIrydRISQWLQRLEQ 12612
Cdd:PRK11281 248 eainskrLTLSEKTVQEAQSQDEAARI-QANPLV-AQELEINLQLSQrLLKAT-EKLNTLTQQNL---RVKNWLDRLTQ 320
|
|
| SPEC |
smart00150 |
Spectrin repeats; |
12705-12810 |
1.29e-04 |
|
Spectrin repeats;
Pssm-ID: 197544 [Multi-domain] Cd Length: 101 Bit Score: 45.40 E-value: 1.29e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 320544544 12705 RLEERIALIRAWLFEVESQLDKPLNFESytPNVIEAKLKEHEQIQRSIEHHSSNVGEVLNLVEMLLNDADSwrtqvNTSG 12784
Cdd:smart00150 2 QFLRDADELEAWLEEKEQLLASEDLGKD--LESVEALLKKHEAFEAELEAHEERVEALNELGEQLIEEGHP-----DAEE 74
|
90 100
....*....|....*....|....*.
gi 320544544 12785 LAASAQNLEQRWKNVCSQSAERKARI 12810
Cdd:smart00150 75 IEERLEELNERWEELKELAEERRQKL 100
|
|
| SPEC |
smart00150 |
Spectrin repeats; |
13308-13376 |
1.30e-04 |
|
Spectrin repeats;
Pssm-ID: 197544 [Multi-domain] Cd Length: 101 Bit Score: 45.40 E-value: 1.30e-04
10 20 30 40 50 60 70
....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 320544544 13308 EFHQTIGELVEWLQRTEQNIKASE-PVDLTEersvLETKFKKFKDLRAELERCEPRVVSLQDAADQLLRS 13376
Cdd:smart00150 2 QFLRDADELEAWLEEKEQLLASEDlGKDLES----VEALLKKHEAFEAELEAHEERVEALNELGEQLIEE 67
|
|
| COG4995 |
COG4995 |
Uncharacterized conserved protein, contains CHAT domain [Function unknown]; |
12228-12726 |
1.43e-04 |
|
Uncharacterized conserved protein, contains CHAT domain [Function unknown];
Pssm-ID: 444019 [Multi-domain] Cd Length: 711 Bit Score: 49.58 E-value: 1.43e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 320544544 12228 LRQLKERHQNSEVAPSVASSDDDGILEVLALWQKIFQDTFQEYHRLSTRLARSQNSSEALRLWRQYLQHVQSFLSCAIPE 12307
Cdd:COG4995 1 LLALALLALLAALLAALALALLALALLLLLAALAAAALLLLALLALLLALAAAAAAALAAAALALALLAAAALALLLLAL 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 320544544 12308 DYSSLREQQQLCAIHQNLLISQQSVLSETPLESELSEQYKALTNLHNETLSRIMQRNGELERRVSGWNAYRQQLAALLDW 12387
Cdd:COG4995 81 ALAALALALLAAALALALAAAALAALALLAALLALAAAAALLALLAALALLALLAALAAALAAAAAAALAAALAAAAAAA 160
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 320544544 12388 LRQREAERNALQLRYIHLKRvphLKHRLDAMIQQLDQGEQQSKALQEQQQELARHCDDALATAMRMEQASIGQRISNLRA 12467
Cdd:COG4995 161 AAAALLALALALAAAALALL---ALLLAALAAALAAAAAALALLLALLLLAALAAALAAALAALLLALLALAAALLALLL 237
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 320544544 12468 ALKTWQGFLQRVTQLSESYEQRVNQLQQEFGAAQKLLDANSESLPTQPAAIEQLLGSLRAQRVQLGAQVSALESLTVTQE 12547
Cdd:COG4995 238 LALLALAAAAAALAAAAAALLALAAALLLLAALAALAAAAAAAALAALALAAALALAAAALALALLLAAAAAAALAALAL 317
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 320544544 12548 ELKEcisphdmkTIRQRNWLLWQQHADLDYQLANLINSIEERLSLLSNYQIRYDRISQWLQRLEQRVEKDADvtamtnpe 12627
Cdd:COG4995 318 LLLA--------ALLLLLAALALLALLLLLAAAALLAAALAAALALAAALALALLAALLLLLAALLALLLEA-------- 381
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 320544544 12628 QAAKQLEQQVNSELQLRDKEREWLLSTSRELLTLYSEPEVRSQVQQQSDSLIdrwQRLKYLAKQKatkigelkmtllRLE 12707
Cdd:COG4995 382 LLLLLLALLAALLLLAAALLALAAAQLLRLLLAALALLLALAAYAAARLALL---ALIEYIILPD------------RLY 446
|
490 500
....*....|....*....|
gi 320544544 12708 ERIALIRaWLFE-VESQLDK 12726
Cdd:COG4995 447 AFVQLYQ-LLIApIEAELPG 465
|
|
| SPEC |
smart00150 |
Spectrin repeats; |
13197-13300 |
2.06e-04 |
|
Spectrin repeats;
Pssm-ID: 197544 [Multi-domain] Cd Length: 101 Bit Score: 44.63 E-value: 2.06e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 320544544 13197 QQIDNDLWRLEQWLQFAEsTQKAQSAPPSNIELLEDVTQDHREFLLDLESHKSIISSLNVVGDHLAthTLDTEKARQLRS 13276
Cdd:smart00150 1 QQFLRDADELEAWLEEKE-QLLASEDLGKDLESVEALLKKHEAFEAELEAHEERVEALNELGEQLI--EEGHPDAEEIEE 77
|
90 100
....*....|....*....|....
gi 320544544 13277 RLEADNERWNNVCINATKWQGLLQ 13300
Cdd:smart00150 78 RLEELNERWEELKELAEERRQKLE 101
|
|
| SPEC |
cd00176 |
Spectrin repeats, found in several proteins involved in cytoskeletal structure; family members ... |
13308-13394 |
2.22e-04 |
|
Spectrin repeats, found in several proteins involved in cytoskeletal structure; family members include spectrin, alpha-actinin and dystrophin; the spectrin repeat forms a three helix bundle with the second helix interrupted by proline in some sequences; the repeats are independent folding units; tandem repeats are found in differing numbers and arrange in an antiparallel manner to form dimers; the repeats are defined by a characteristic tryptophan (W) residue in helix A and a leucine (L) at the carboxyl end of helix C and separated by a linker of 5 residues; two copies of the repeat are present here
Pssm-ID: 238103 [Multi-domain] Cd Length: 213 Bit Score: 47.06 E-value: 2.22e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 320544544 13308 EFHQTIGELVEWLQRTEQNIKASEPVDLTEErsvLETKFKKFKDLRAELERCEPRVVSLQDAADQLLRSVEGSEQQSQHT 13387
Cdd:cd00176 4 QFLRDADELEAWLSEKEELLSSTDYGDDLES---VEALLKKHEALEAELAAHEERVEALNELGEQLIEEGHPDAEEIQER 80
|
....*..
gi 320544544 13388 YERTLSR 13394
Cdd:cd00176 81 LEELNQR 87
|
|
| GumC |
COG3206 |
Exopolysaccharide export protein/domain GumC/Wzc1 [Cell wall/membrane/envelope biogenesis]; |
12095-12441 |
2.93e-04 |
|
Exopolysaccharide export protein/domain GumC/Wzc1 [Cell wall/membrane/envelope biogenesis];
Pssm-ID: 442439 [Multi-domain] Cd Length: 687 Bit Score: 48.86 E-value: 2.93e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 320544544 12095 KSLEQPLDALQHAKVCQDNLTTQNdRILELRDIVAKIAADVGLDASALMQG-ELDALGQRLaecKDAITtLANVAET--- 12170
Cdd:COG3206 64 QSSDVLLSGLSSLSASDSPLETQI-EILKSRPVLERVVDKLNLDEDPLGEEaSREAAIERL---RKNLT-VEPVKGSnvi 138
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 320544544 12171 ----QDKERkELDKEV--TLAKAYFNNVQQDISREAPQNPKESEEQLAALRahlQTLARTEEQLRQLKERHQnsevapSV 12244
Cdd:COG3206 139 eisyTSPDP-ELAAAVanALAEAYLEQNLELRREEARKALEFLEEQLPELR---KELEEAEAALEEFRQKNG------LV 208
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 320544544 12245 ASSDDDGILEvlalwqkifqdtfQEYHRLSTRLARSQNSSEALRLWRQYLQHVQSFLSCAIPEdysslreqqqlcaihqn 12324
Cdd:COG3206 209 DLSEEAKLLL-------------QQLSELESQLAEARAELAEAEARLAALRAQLGSGPDALPE----------------- 258
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 320544544 12325 llisqqsvLSETPLESELSEQYKALtnlhNETLSRIMQRNGELERRVsgwNAYRQQLAALLDWLRQrEAERNALQLRyih 12404
Cdd:COG3206 259 --------LLQSPVIQQLRAQLAEL----EAELAELSARYTPNHPDV---IALRAQIAALRAQLQQ-EAQRILASLE--- 319
|
330 340 350
....*....|....*....|....*....|....*..
gi 320544544 12405 lKRVPHLKHRLDAMIQQLDQGEQQSKALQEQQQELAR 12441
Cdd:COG3206 320 -AELEALQAREASLQAQLAQLEARLAELPELEAELRR 355
|
|
| SMC_prok_B |
TIGR02168 |
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ... |
11268-12195 |
4.71e-04 |
|
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]
Pssm-ID: 274008 [Multi-domain] Cd Length: 1179 Bit Score: 48.13 E-value: 4.71e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 320544544 11268 EEKLDNYNQLNDELSTIKQNVVQLERQLSKAEpepqllqcvdSLKEHVDAVEQVTQQNQVQDSNDL-DKWHNFEvllynv 11346
Cdd:TIGR02168 182 ERTRENLDRLEDILNELERQLKSLERQAEKAE----------RYKELKAELRELELALLVLRLEELrEELEELQ------ 245
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 320544544 11347 sSVLADLQQSYDLLINQeypLSAKLAQLDELEQQHEAAQQQLAHLcqnarafQRDFpgkkmpqdvHNAFETSKNIANNIQ 11426
Cdd:TIGR02168 246 -EELKEAEEELEELTAE---LQELEEKLEELRLEVSELEEEIEEL-------QKEL---------YALANEISRLEQQKQ 305
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 320544544 11427 AERERVLQLQSLAEEYE-QTLKEFTKITVLADKLVEspiVSSSLEQLNNEVQKQRKFFVNLSHCRAMLESLEENIDSETR 11505
Cdd:TIGR02168 306 ILRERLANLERQLEELEaQLEELESKLDELAEELAE---LEEKLEELKEELESLEAELEELEAELEELESRLEELEEQLE 382
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 320544544 11506 EKHSELHkELYNRATSLldkASERSSklvqaasrwtvlekgMRDELQWLQVAQQRvpdLSAVTSAdydqyttlyqsLSND 11585
Cdd:TIGR02168 383 TLRSKVA-QLELQIASL---NNEIER---------------LEARLERLEDRRER---LQQEIEE-----------LLKK 429
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 320544544 11586 ISHHYVKMTQlSGIANKLQLLVQAPNLVEETNEALIvllKLREEVALYLHRLLVFKEIWVQYEQQTDKLEAFVREAEQEL 11665
Cdd:TIGR02168 430 LEEAELKELQ-AELEELEEELEELQEELERLEEALE---ELREELEEAEQALDAAERELAQLQARLDSLERLQENLEGFS 505
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 320544544 11666 RNIQIPSQPTHQPIEHMRQFWEIkarfelhnnVRTDTGlsFEKSLQVipLADEMLQrqfhAQLEDRWQAVAQAIE-LIQH 11744
Cdd:TIGR02168 506 EGVKALLKNQSGLSGILGVLSEL---------ISVDEG--YEAAIEA--ALGGRLQ----AVVVENLNAAKKAIAfLKQN 568
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 320544544 11745 NIVECLSSE-DVPADEKLKMVERE-LQEIYLTMTSMKGVIKNEEEL----------CLYIERVQ---------------- 11796
Cdd:TIGR02168 569 ELGRVTFLPlDSIKGTEIQGNDREiLKNIEGFLGVAKDLVKFDPKLrkalsyllggVLVVDDLDnalelakklrpgyriv 648
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 320544544 11797 ----VLRTRVGFI--GNELGRIGLQEPAIEPEKVGELFslshKISTQIAEELEGA-SVLRDQLQAIQEGISNQRKHQAKI 11869
Cdd:TIGR02168 649 tldgDLVRPGGVItgGSAKTNSSILERRREIEELEEKI----EELEEKIAELEKAlAELRKELEELEEELEQLRKELEEL 724
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 320544544 11870 SVILDECE---AAERQGADVLEKAVADCQAAGEELViswQEIMRIRQMLHTLPMRLK-MSVSPVKLERDISQLQDDHAFL 11945
Cdd:TIGR02168 725 SRQISALRkdlARLEAEVEQLEERIAQLSKELTELE---AEIEELEERLEEAEEELAeAEAEIEELEAQIEQLKEELKAL 801
|
730 740 750 760 770 780 790 800
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 320544544 11946 ESKCTNIMAILRsRLAVwlRYERQLELVHGSVQEtdfmMELIRVHGQVDYERLRKATERLEGLAGDLHNREQLIDELKGA 12025
Cdd:TIGR02168 802 REALDELRAELT-LLNE--EAANLRERLESLERR----IAATERRLEDLEEQIEELSEDIESLAAEIEELEELIEELESE 874
|
810 820 830 840 850 860 870 880
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 320544544 12026 AKPLIESCDVQIV--EQIESAVQEAVVAWNDTSENLQQLRTRYQRAVELWDKYRNASAAVKNSIDQQMDAVKSLEQplDA 12103
Cdd:TIGR02168 875 LEALLNERASLEEalALLRSELEELSEELRELESKRSELRRELEELREKLAQLELRLEGLEVRIDNLQERLSEEYS--LT 952
|
890 900 910 920 930 940 950 960
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 320544544 12104 LQHAKVCQDNLTTQNDRI-LELRDIVAKIAA--DVGLDASAlmqgELDALGQRL-------AECKDAITTLANVAETQDK 12173
Cdd:TIGR02168 953 LEEAEALENKIEDDEEEArRRLKRLENKIKElgPVNLAAIE----EYEELKERYdfltaqkEDLTEAKETLEEAIEEIDR 1028
|
970 980
....*....|....*....|..
gi 320544544 12174 ERKELDKEVtlakayFNNVQQD 12195
Cdd:TIGR02168 1029 EARERFKDT------FDQVNEN 1044
|
|
| SMC_prok_B |
TIGR02168 |
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ... |
75-351 |
5.04e-04 |
|
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]
Pssm-ID: 274008 [Multi-domain] Cd Length: 1179 Bit Score: 48.13 E-value: 5.04e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 320544544 75 IENCRnsEEKTLVQTTIDQLAASLAQVRGWLDEKKQAVGDSLDAWTRfmnlyqivmswasEKRNFIDQTIELRTLPEARN 154
Cdd:TIGR02168 679 IEELE--EKIEELEEKIAELEKALAELRKELEELEEELEQLRKELEE-------------LSRQISALRKDLARLEAEVE 743
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 320544544 155 KLNDYVTSvksikpIVKHLSEMDKELEhigqvttvgDLKDKLQEAEDAKISVEAVLLERNSLLQEACEEWDQCERKIKDI 234
Cdd:TIGR02168 744 QLEERIAQ------LSKELTELEAEIE---------ELEERLEEAEEELAEAEAEIEELEAQIEQLKEELKALREALDEL 808
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 320544544 235 RSWHEKTKQGLDSSQQQKKPLRDQLGFCEKTLADINVQKTKLRLSIEKLEvHFRNGMGGDPR------------------ 296
Cdd:TIGR02168 809 RAELTLLNEEAANLRERLESLERRIAATERRLEDLEEQIEELSEDIESLA-AEIEELEELIEeleseleallneraslee 887
|
250 260 270 280 290
....*....|....*....|....*....|....*....|....*....|....*....
gi 320544544 297 ----LSENVDDLVRVLDGLGELVKAKSQSLEQTLAQIDVYQQQMQSLRQRIIQEEQQLR 351
Cdd:TIGR02168 888 alalLRSELEELSEELRELESKRSELRRELEELREKLAQLELRLEGLEVRIDNLQERLS 946
|
|
| EnvC |
COG4942 |
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, ... |
194-393 |
5.04e-04 |
|
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, cell division, chromosome partitioning];
Pssm-ID: 443969 [Multi-domain] Cd Length: 377 Bit Score: 47.45 E-value: 5.04e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 320544544 194 DKLQEAEDAKISVEAVLLERNSLLQEAceewdqcERKIKDIRSWHEKTKQGLDSSQQQKKPLRDQLGFCEKTLADINVQK 273
Cdd:COG4942 20 DAAAEAEAELEQLQQEIAELEKELAAL-------KKEEKALLKQLAALERRIAALARRIRALEQELAALEAELAELEKEI 92
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 320544544 274 TKLRLSIEKLE--------VHFRNGMGGDPRL---SENVDDLVRVLDGLGELVKA-----------------KSQSLEQT 325
Cdd:COG4942 93 AELRAELEAQKeelaellrALYRLGRQPPLALllsPEDFLDAVRRLQYLKYLAPArreqaeelradlaelaaLRAELEAE 172
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 320544544 326 LAQIDVYQQQMQSLRQRIIQEEQQLRLVMA--PTYLPHDRERA---LAEQQAMRESIDGMQQVYDATARKSYA 393
Cdd:COG4942 173 RAELEALLAELEEERAALEALKAERQKLLArlEKELAELAAELaelQQEAEELEALIARLEAEAAAAAERTPA 245
|
|
| COG4913 |
COG4913 |
Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown]; |
12972-13122 |
1.03e-03 |
|
Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];
Pssm-ID: 443941 [Multi-domain] Cd Length: 1089 Bit Score: 47.22 E-value: 1.03e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 320544544 12972 QRLESLEKKLQDAQQHVQQADNLAQEAKTRTKQQPQLKQLLELVSAYTTL---WQTVQTRIVTLkttwltRAAQAAASLP 13048
Cdd:COG4913 610 AKLAALEAELAELEEELAEAEERLEALEAELDALQERREALQRLAEYSWDeidVASAEREIAEL------EAELERLDAS 683
|
90 100 110 120 130 140 150
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 320544544 13049 VSEAANAAVQVNTLsQRKLRQAQQMQRETSITakdayIMELQTAITECQNNLDELQRTVVDKTRKPGPQKIAKL 13122
Cdd:COG4913 684 SDDLAALEEQLEEL-EAELEELEEELDELKGE-----IGRLEKELEQAEEELDELQDRLEAAEDLARLELRALL 751
|
|
| EnvC |
COG4942 |
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, ... |
12918-13124 |
1.06e-03 |
|
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, cell division, chromosome partitioning];
Pssm-ID: 443969 [Multi-domain] Cd Length: 377 Bit Score: 46.30 E-value: 1.06e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 320544544 12918 ALLDAIDKDAKLMREFNNAQLEATNSLNAIQKALEQLpsAENQQTSKAEPKAVLQRLESLEKKLQDAQ-QHVQQADNLAQ 12996
Cdd:COG4942 31 QLQQEIAELEKELAALKKEEKALLKQLAALERRIAAL--ARRIRALEQELAALEAELAELEKEIAELRaELEAQKEELAE 108
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 320544544 12997 EAKT--RTKQQPQLK---------QLLELVSAYTTLWQTVQTRIVTLKTTW-----LTRAAQAAASLPVSEAANAAVQVN 13060
Cdd:COG4942 109 LLRAlyRLGRQPPLAlllspedflDAVRRLQYLKYLAPARREQAEELRADLaelaaLRAELEAERAELEALLAELEEERA 188
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 320544544 13061 TLSQRKLRQAQQMQR-ETSITAKDAYIMELQTAITECQNNLDELQRTVVDKTRKPGPQKIAKLLG 13124
Cdd:COG4942 189 ALEALKAERQKLLARlEKELAELAAELAELQQEAEELEALIARLEAEAAAAAERTPAAGFAALKG 253
|
|
| SPEC |
cd00176 |
Spectrin repeats, found in several proteins involved in cytoskeletal structure; family members ... |
12816-13032 |
1.76e-03 |
|
Spectrin repeats, found in several proteins involved in cytoskeletal structure; family members include spectrin, alpha-actinin and dystrophin; the spectrin repeat forms a three helix bundle with the second helix interrupted by proline in some sequences; the repeats are independent folding units; tandem repeats are found in differing numbers and arrange in an antiparallel manner to form dimers; the repeats are defined by a characteristic tryptophan (W) residue in helix A and a leucine (L) at the carboxyl end of helix C and separated by a linker of 5 residues; two copies of the repeat are present here
Pssm-ID: 238103 [Multi-domain] Cd Length: 213 Bit Score: 44.36 E-value: 1.76e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 320544544 12816 LLQQLIKLTAEHKNWLGKQESQIAGFERDQKSHSKHKLEERQMELRAKLEELESQsvnLRQLEQIYAKLAMSAGVEPENI 12895
Cdd:cd00176 1 KLQQFLRDADELEAWLSEKEELLSSTDYGDDLESVEALLKKHEALEAELAAHEER---VEALNELGEQLIEEGHPDAEEI 77
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 320544544 12896 QKlTLptKVMVSMWRQLTPRCHALLDAIDKDAKLMREFNNAqLEATNSLNAIQKALEQLPSAEnqqtSKAEPKAVLQRLE 12975
Cdd:cd00176 78 QE-RL--EELNQRWEELRELAEERRQRLEEALDLQQFFRDA-DDLEQWLEEKEAALASEDLGK----DLESVEELLKKHK 149
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|
gi 320544544 12976 SLEKKLQDAQQHVQQADNLAQ---EAKTRTKQQPQLKQLLELVSAYTTLWQTVQTRIVTL 13032
Cdd:cd00176 150 ELEEELEAHEPRLKSLNELAEellEEGHPDADEEIEEKLEELNERWEELLELAEERQKKL 209
|
|
| rne |
PRK10811 |
ribonuclease E; Reviewed |
10668-10827 |
1.81e-03 |
|
ribonuclease E; Reviewed
Pssm-ID: 236766 [Multi-domain] Cd Length: 1068 Bit Score: 46.19 E-value: 1.81e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 320544544 10668 EDAVVSSP--SESPRTPMVELVIPTEVVELA--LVEDEEQQTTPRIPSPTEKSEVEQDIKSVQTSPQHQPKLDETAV--- 10740
Cdd:PRK10811 861 AEEVQVQPvvAEVPVAAAVEPVVSAPVVEAVaeVVEEPVVVAEPQPEEVVVVETTHPEVIAAPVTEQPQVITESDVAvaq 940
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 320544544 10741 QTSLEVQPDNQENESQTLIVEITETEAQTTPRSEEQSVAVEISTTEIQTDVSGQPAETVEISSQTTVTTTIEKELQTTPK 10820
Cdd:PRK10811 941 EVAEHAEPVVEPQDETADIEEAAETAEVVVAEPEVVAQPAAPVVAEVAAEVETVTAVEPEVAPAQVPEATVEHNHATAPM 1020
|
....*..
gi 320544544 10821 DSPRAPE 10827
Cdd:PRK10811 1021 TRAPAPE 1027
|
|
| SMC_prok_A |
TIGR02169 |
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of ... |
12144-12980 |
2.01e-03 |
|
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. It is found in a single copy and is homodimeric in prokaryotes, but six paralogs (excluded from this family) are found in eukarotes, where SMC proteins are heterodimeric. This family represents the SMC protein of archaea and a few bacteria (Aquifex, Synechocystis, etc); the SMC of other bacteria is described by TIGR02168. The N- and C-terminal domains of this protein are well conserved, but the central hinge region is skewed in composition and highly divergent. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]
Pssm-ID: 274009 [Multi-domain] Cd Length: 1164 Bit Score: 46.21 E-value: 2.01e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 320544544 12144 QGELDALGQRLAECKDAITTLA-NVAETQDKERKELDKEVTLAKAYFNNVQQDIsREAPQNPKESEEQLAALRAHLQTLA 12222
Cdd:TIGR02169 257 TEEISELEKRLEEIEQLLEELNkKIKDLGEEEQLRVKEKIGELEAEIASLERSI-AEKERELEDAEERLAKLEAEIDKLL 335
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 320544544 12223 RTEEQLRQLKERhQNSEVAPsvassdddgilevlalWQKIFQDTFQEYHRLstrLARSQNSSEALRLWRQYLQHVQSFLS 12302
Cdd:TIGR02169 336 AEIEELEREIEE-ERKRRDK----------------LTEEYAELKEELEDL---RAELEEVDKEFAETRDELKDYREKLE 395
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 320544544 12303 CAIPEDYSSLREQQQLCAIHQNllisqqsvlsetpLESELSEqykaltnlHNETLSRIMQRNGELERRvsgwnayRQQLA 12382
Cdd:TIGR02169 396 KLKREINELKRELDRLQEELQR-------------LSEELAD--------LNAAIAGIEAKINELEEE-------KEDKA 447
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 320544544 12383 ALLdwlrqREAERNALQLRYIhlkrvphlkhrLDAMIQQLDQGEQQSKALQEQQQELARHCDDALATAMRMEQASIGQRI 12462
Cdd:TIGR02169 448 LEI-----KKQEWKLEQLAAD-----------LSKYEQELYDLKEEYDRVEKELSKLQRELAEAEAQARASEERVRGGRA 511
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 320544544 12463 SN--LRAALktwQGFLQRVTQLSESYEQRVNQLQQEFGAAQKLLDANSESlpTQPAAIEQLlgslraQRVQLGaqvsale 12540
Cdd:TIGR02169 512 VEevLKASI---QGVHGTVAQLGSVGERYATAIEVAAGNRLNNVVVEDDA--VAKEAIELL------KRRKAG------- 573
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 320544544 12541 slTVTQEELKECISPHDMKTIRQRNWLLwqQHA----DLDYQLAN----------LINSIEERLSLLSNYQirydrisqw 12606
Cdd:TIGR02169 574 --RATFLPLNKMRDERRDLSILSEDGVI--GFAvdlvEFDPKYEPafkyvfgdtlVVEDIEAARRLMGKYR--------- 640
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 320544544 12607 LQRLE-QRVEKDADVTAMTNPEQ-----AAKQLE--QQVNSELQLRDKEREWLLSTSRELLTLYSEPEVRSQVQQQSDSL 12678
Cdd:TIGR02169 641 MVTLEgELFEKSGAMTGGSRAPRggilfSRSEPAelQRLRERLEGLKRELSSLQSELRRIENRLDELSQELSDASRKIGE 720
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 320544544 12679 ID-RWQRLKYLAKQKATKIGELKMTLLRLEERIALIRAWLFEVESQLDK---PLNFESYTPNVIEAKLKEH--EQIQRSI 12752
Cdd:TIGR02169 721 IEkEIEQLEQEEEKLKERLEELEEDLSSLEQEIENVKSELKELEARIEEleeDLHKLEEALNDLEARLSHSriPEIQAEL 800
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 320544544 12753 ----EHHSSNVGeVLNLVEMLLNDADSWRTQvntsgLAASAQNLEQRWKNVCSQSAERKARILTIWNLLQQLIKLTAEHK 12828
Cdd:TIGR02169 801 skleEEVSRIEA-RLREIEQKLNRLTLEKEY-----LEKEIQELQEQRIDLKEQIKSIEKEIENLNGKKEELEEELEELE 874
|
730 740 750 760 770 780 790 800
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 320544544 12829 NWLGKQESQIAGFERDQKSHSKH--KLEERQMELRAKLEELESQSvnLRQLEQIYAKLAMSAGVEPENIQKLTLPTKVMV 12906
Cdd:TIGR02169 875 AALRDLESRLGDLKKERDELEAQlrELERKIEELEAQIEKKRKRL--SELKAKLEALEEELSEIEDPKGEDEEIPEEELS 952
|
810 820 830 840 850 860 870
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 320544544 12907 smWRQLTPRCHALLDAIDKdaklMREFNNAQLEATNSLNAIQKALEqlpsaENQQTSKAEPKAVLQRLESLEKK 12980
Cdd:TIGR02169 953 --LEDVQAELQRVEEEIRA----LEPVNMLAIQEYEEVLKRLDELK-----EKRAKLEEERKAILERIEEYEKK 1015
|
|
| EnvC |
COG4942 |
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, ... |
12200-12469 |
2.03e-03 |
|
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, cell division, chromosome partitioning];
Pssm-ID: 443969 [Multi-domain] Cd Length: 377 Bit Score: 45.53 E-value: 2.03e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 320544544 12200 APQNPKESEEQLAALRahlQTLARTEEQLRQLKERHQNSEVApsVASSDDdgilEVLALWQKIfQDTFQEYHRLSTRLAR 12279
Cdd:COG4942 18 QADAAAEAEAELEQLQ---QEIAELEKELAALKKEEKALLKQ--LAALER----RIAALARRI-RALEQELAALEAELAE 87
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 320544544 12280 SQNSSEALRlwrqylqhvqsflscaipEDYSSLREQ--QQLCAIHQNLLISQQSVL--SETPLESELSEQY-KALTNLHN 12354
Cdd:COG4942 88 LEKEIAELR------------------AELEAQKEElaELLRALYRLGRQPPLALLlsPEDFLDAVRRLQYlKYLAPARR 149
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 320544544 12355 ETLSRIMQRNGELERRVSGWNAYRQQLAALLDwlrQREAERNALQLRYIHLKRVphlkhrLDAMIQQLDQGEQQSKALQE 12434
Cdd:COG4942 150 EQAEELRADLAELAALRAELEAERAELEALLA---ELEEERAALEALKAERQKL------LARLEKELAELAAELAELQQ 220
|
250 260 270
....*....|....*....|....*....|....*
gi 320544544 12435 QQQELARHCDDALATAMRMEQASIGQRISNLRAAL 12469
Cdd:COG4942 221 EAEELEALIARLEAEAAAAAERTPAAGFAALKGKL 255
|
|
| SPEC |
cd00176 |
Spectrin repeats, found in several proteins involved in cytoskeletal structure; family members ... |
11994-12156 |
2.52e-03 |
|
Spectrin repeats, found in several proteins involved in cytoskeletal structure; family members include spectrin, alpha-actinin and dystrophin; the spectrin repeat forms a three helix bundle with the second helix interrupted by proline in some sequences; the repeats are independent folding units; tandem repeats are found in differing numbers and arrange in an antiparallel manner to form dimers; the repeats are defined by a characteristic tryptophan (W) residue in helix A and a leucine (L) at the carboxyl end of helix C and separated by a linker of 5 residues; two copies of the repeat are present here
Pssm-ID: 238103 [Multi-domain] Cd Length: 213 Bit Score: 43.97 E-value: 2.52e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 320544544 11994 DYERLRKATERLEGLAGDLHNREQLIDELKGAAKPLIESCDVQIvEQIESAVQEAVVAWNDTSENLQQLRTRYQRAVELW 12073
Cdd:cd00176 31 DLESVEALLKKHEALEAELAAHEERVEALNELGEQLIEEGHPDA-EEIQERLEELNQRWEELRELAEERRQRLEEALDLQ 109
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 320544544 12074 DKYRNASAAV-----KNSIDQQMDAVKSLEQPLDALQHAKVCQDNLTTQNDRILELRDIVAKIAADVGLDASALMQGELD 12148
Cdd:cd00176 110 QFFRDADDLEqwleeKEAALASEDLGKDLESVEELLKKHKELEEELEAHEPRLKSLNELAEELLEEGHPDADEEIEEKLE 189
|
....*...
gi 320544544 12149 ALGQRLAE 12156
Cdd:cd00176 190 ELNERWEE 197
|
|
| SPEC |
smart00150 |
Spectrin repeats; |
9648-9742 |
2.59e-03 |
|
Spectrin repeats;
Pssm-ID: 197544 [Multi-domain] Cd Length: 101 Bit Score: 41.55 E-value: 2.59e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 320544544 9648 EYQQHLLELEQWIIEVSAELASfeptSDSSTDEQVLKSQVERSQQLLRTLKDRQQSMEDLVEQTRQL-QSHPDVSPLADT 9726
Cdd:smart00150 2 QFLRDADELEAWLEEKEQLLAS----EDLGKDLESVEALLKKHEAFEAELEAHEERVEALNELGEQLiEEGHPDAEEIEE 77
|
90
....*....|....*.
gi 320544544 9727 LMEQLQSIITILREQV 9742
Cdd:smart00150 78 RLEELNERWEELKELA 93
|
|
| Spectrin |
pfam00435 |
Spectrin repeat; Spectrin repeat-domains are found in several proteins involved in ... |
13308-13374 |
2.60e-03 |
|
Spectrin repeat; Spectrin repeat-domains are found in several proteins involved in cytoskeletal structure. These include spectrin, alpha-actinin and dystrophin. The sequence repeat used in this family is taken from the structural repeat in reference. The spectrin domain- repeat forms a three helix bundle. The second helix is interrupted by proline in some sequences. The repeats are defined by a characteriztic tryptophan (W) residue at position 17 in helix A and a leucine (L) at 2 residues from the carboxyl end of helix C. Although the domain occurs in multiple repeats along sequences, the domains are actually stable on their own - ie they act, biophysically, like domains rather than repeats that along function when aggregated.
Pssm-ID: 395348 [Multi-domain] Cd Length: 105 Bit Score: 41.54 E-value: 2.60e-03
10 20 30 40 50 60
....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 320544544 13308 EFHQTIGELVEWLQRTEQNIKASE-PVDLTEersvLETKFKKFKDLRAELERCEPRVVSLQDAADQLL 13374
Cdd:pfam00435 5 QFFRDADDLESWIEEKEALLSSEDyGKDLES----VQALLKKHKALEAELAAHQDRVEALNELAEKLI 68
|
|
| PRK09039 |
PRK09039 |
peptidoglycan -binding protein; |
12330-12531 |
3.36e-03 |
|
peptidoglycan -binding protein;
Pssm-ID: 181619 [Multi-domain] Cd Length: 343 Bit Score: 44.57 E-value: 3.36e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 320544544 12330 QSVLSEtplesELSEQYKALTNLH------NETLSRIMQRNGELERrvsgwnayrqQLAALLDWLRQREAERNALQlryi 12403
Cdd:PRK09039 41 QFFLSR-----EISGKDSALDRLNsqiaelADLLSLERQGNQDLQD----------SVANLRASLSAAEAERSRLQ---- 101
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 320544544 12404 hlkrvphlkhrldamiQQLDQGEQQSKALQEQQQELARhcddALAtamrmEQASIGQRIsnlraalktwqgfLQRVTQLS 12483
Cdd:PRK09039 102 ----------------ALLAELAGAGAAAEGRAGELAQ----ELD-----SEKQVSARA-------------LAQVELLN 143
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|.
gi 320544544 12484 esyeQRVNQLQQEFGAAQKLLDANSESLPTQPAAIEQL---LGSLRAQRVQ 12531
Cdd:PRK09039 144 ----QQIAALRRQLAALEAALDASEKRDRESQAKIADLgrrLNVALAQRVQ 190
|
|
| EnvC |
COG4942 |
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, ... |
184-382 |
3.47e-03 |
|
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, cell division, chromosome partitioning];
Pssm-ID: 443969 [Multi-domain] Cd Length: 377 Bit Score: 44.75 E-value: 3.47e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 320544544 184 GQVTTVGDLKDKLQEAEDAKISVEAVLLERNSLLQEACEEWDQCERKIKDIRSWHEKTKQGLDSSQQQKKPLRDQLgfcE 263
Cdd:COG4942 17 AQADAAAEAEAELEQLQQEIAELEKELAALKKEEKALLKQLAALERRIAALARRIRALEQELAALEAELAELEKEI---A 93
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 320544544 264 KTLADINVQKTKLRlsiEKLEVHFRNGMGGDPRL---SENVDDLVRVLDGLGELVKAksqsLEQTLAQIDVYQQQMQSLR 340
Cdd:COG4942 94 ELRAELEAQKEELA---ELLRALYRLGRQPPLALllsPEDFLDAVRRLQYLKYLAPA----RREQAEELRADLAELAALR 166
|
170 180 190 200
....*....|....*....|....*....|....*....|..
gi 320544544 341 QRIIQEEQQLrlvmaptylphdrERALAEQQAMRESIDGMQQ 382
Cdd:COG4942 167 AELEAERAEL-------------EALLAELEEERAALEALKA 195
|
|
| PRK11281 |
PRK11281 |
mechanosensitive channel MscK; |
12943-13105 |
3.53e-03 |
|
mechanosensitive channel MscK;
Pssm-ID: 236892 [Multi-domain] Cd Length: 1113 Bit Score: 45.29 E-value: 3.53e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 320544544 12943 SLNAIQKALEQLPSAENQQtskAEPKAVLQRLE-----------------SLEKKLQDAQQHVQQA----DNLAQEAKTR 13001
Cdd:PRK11281 37 TEADVQAQLDALNKQKLLE---AEDKLVQQDLEqtlalldkidrqkeeteQLKQQLAQAPAKLRQAqaelEALKDDNDEE 113
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 320544544 13002 TKQQ------PQLKQLLELVSAYTTLWQ----TVQTRIVTLKTtwLTRAAQAAaslpVSEAANAAVQVNTL------SQR 13065
Cdd:PRK11281 114 TRETlstlslRQLESRLAQTLDQLQNAQndlaEYNSQLVSLQT--QPERAQAA----LYANSQRLQQIRNLlkggkvGGK 187
|
170 180 190 200
....*....|....*....|....*....|....*....|....*
gi 320544544 13066 KLRQAQQMQRETSITAKDAYImELQTaiTECQNN-----LDELQR 13105
Cdd:PRK11281 188 ALRPSQRVLLQAEQALLNAQN-DLQR--KSLEGNtqlqdLLQKQR 229
|
|
| MscS_porin |
pfam12795 |
Mechanosensitive ion channel porin domain; The small mechanosensitive channel, MscS, is a part ... |
12414-12589 |
3.74e-03 |
|
Mechanosensitive ion channel porin domain; The small mechanosensitive channel, MscS, is a part of the turgor-driven solute efflux system that protects bacteria from lysis in the event of osmotic shock. The MscS protein alone is sufficient to form a functional mechanosensitive channel gated directly by tension in the lipid bilayer. The MscS proteins are heptamers of three transmembrane subunits with seven converging M3 domains, and this MscS_porin is towards the N-terminal of the molecules. The high concentration of negative charges at the extracellular entrance of the pore helps select the cations for efflux.
Pssm-ID: 432790 [Multi-domain] Cd Length: 238 Bit Score: 43.83 E-value: 3.74e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 320544544 12414 RLDAMIQQLDQGEQQSKALQEQQQELARHCDDALATAMR-MEQASIGQRISNLRAALKTWQGFLQRVTQLSESYEQRVNQ 12492
Cdd:pfam12795 38 RAAAYQKALDDAPAELRELRQELAALQAKAEAAPKEILAsLSLEELEQRLLQTSAQLQELQNQLAQLNSQLIELQTRPER 117
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 320544544 12493 LQQEFGAAQKLLDANSESLPTQPAAIEQLlgsLRAQRVQLGAQVSALESLTVTQE-ELKecISPHDMKTIRQRNWLLWQQ 12571
Cdd:pfam12795 118 AQQQLSEARQRLQQIRNRLNGPAPPGEPL---SEAQRWALQAELAALKAQIDMLEqELL--SNNNRQDLLKARRDLLTLR 192
|
170
....*....|....*...
gi 320544544 12572 HADLDYQLANLINSIEER 12589
Cdd:pfam12795 193 IQRLEQQLQALQELLNEK 210
|
|
| MukB |
COG3096 |
Chromosome condensin MukBEF, ATPase and DNA-binding subunit MukB [Cell cycle control, cell ... |
9538-9777 |
3.94e-03 |
|
Chromosome condensin MukBEF, ATPase and DNA-binding subunit MukB [Cell cycle control, cell division, chromosome partitioning];
Pssm-ID: 442330 [Multi-domain] Cd Length: 1470 Bit Score: 45.33 E-value: 3.94e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 320544544 9538 QRQKDLITQELDELLQSLSsvedgIANMNQSSLDGMLHGLKLIQSNLEVHE---------RDAIELKNQAKKLPtdpATE 9608
Cdd:COG3096 447 RAKEQQATEEVLELEQKLS-----VADAARRQFEKAYELVCKIAGEVERSQawqtarellRRYRSQQALAQRLQ---QLR 518
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 320544544 9609 RLLNDtvdrIDLLLRRTQQGITMIANAMHGQKKRQQEIDEYQQHLLELEQWIIEVSAELAsfeptsDSSTDEQVLKSQVE 9688
Cdd:COG3096 519 AQLAE----LEQRLRQQQNAERLLEEFCQRIGQQLDAAEELEELLAELEAQLEELEEQAA------EAVEQRSELRQQLE 588
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 320544544 9689 RSQQLLRTLKDR-------QQSMEDLVEQTRQ-LQSHPDVSPLADTLMEQLQSiITILREQVtVATKRifTIEKRIVDLR 9760
Cdd:COG3096 589 QLRARIKELAARapawlaaQDALERLREQSGEaLADSQEVTAAMQQLLERERE-ATVERDEL-AARKQ--ALESQIERLS 664
|
250
....*....|....*..
gi 320544544 9761 KAKSEEAQRQRVLADSL 9777
Cdd:COG3096 665 QPGGAEDPRLLALAERL 681
|
|
| PRK10246 |
PRK10246 |
exonuclease subunit SbcC; Provisional |
12142-12693 |
4.25e-03 |
|
exonuclease subunit SbcC; Provisional
Pssm-ID: 182330 [Multi-domain] Cd Length: 1047 Bit Score: 45.18 E-value: 4.25e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 320544544 12142 LMQGELDALGQRLAECKDAITTLANVAETQDKERKELDKEVTLAKAYfnNVQQDISREAPQNPKESEEQLAALrahlqTL 12221
Cdd:PRK10246 213 LTPEQVQSLTASLQVLTDEEKQLLTAQQQQQQSLNWLTRLDELQQEA--SRRQQALQQALAAEEKAQPQLAAL-----SL 285
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 320544544 12222 ARTEEQLRQLKERHQNSEVAPSVASSDDDGI----LEVLALWQKIFQDTFQEYHRLS---TRLARSQNSSEALRLWRQYL 12294
Cdd:PRK10246 286 AQPARQLRPHWERIQEQSAALAHTRQQIEEVntrlQSTMALRARIRHHAAKQSAELQaqqQSLNTWLAEHDRFRQWNNEL 365
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 320544544 12295 QHVQSFLScAIPEDYSSLRE-QQQLCAIHQNLLISQQSVLSETPLE-----SELSEQY---KALTNLHnETLSRIMQRNG 12365
Cdd:PRK10246 366 AGWRAQFS-QQTSDREQLRQwQQQLTHAEQKLNALPAITLTLTADEvaaalAQHAEQRplrQRLVALH-GQIVPQQKRLA 443
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 320544544 12366 ELERRVSGWNAYRQQLAALLDWLRQREAERNAlqlRYIHLKRVPHLKHRLDAMIQQ------------------------ 12421
Cdd:PRK10246 444 QLQVAIQNVTQEQTQRNAALNEMRQRYKEKTQ---QLADVKTICEQEARIKDLEAQraqlqagqpcplcgstshpaveay 520
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 320544544 12422 -----------LDQGEQQSKALQEQ-----------QQELARhcDDALATAMRMEQASIGQRISNLRAALK---TWQGFL 12476
Cdd:PRK10246 521 qalepgvnqsrLDALEKEVKKLGEEgaalrgqldalTKQLQR--DESEAQSLRQEEQALTQQWQAVCASLNitlQPQDDI 598
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 320544544 12477 QRVTQLSESYEQRVNQLQQEFgAAQKLLDANSESLPTQPAAIEQllgslraQRVQLGAQVSALeSLTVTQEElkeciSPH 12556
Cdd:PRK10246 599 QPWLDAQEEHERQLRLLSQRH-ELQGQIAAHNQQIIQYQQQIEQ-------RQQQLLTALAGY-ALTLPQED-----EEA 664
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 320544544 12557 DMKTIRQRNWLLWQQ----HADLDYQLANL-----------INSIEERLSLLSNYQIRYDRI----SQWlQRLEQRVEKD 12617
Cdd:PRK10246 665 SWLATRQQEAQSWQQrqneLTALQNRIQQLtplletlpqsdDLPHSEETVALDNWRQVHEQClslhSQL-QTLQQQDVLE 743
|
570 580 590 600 610 620 630
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 320544544 12618 AdvtamtnpeQAAKQLEQQVNSELQ---LRDKErewllstsrELLTLYSEPEVRSQVQQQSDSLIDRWQRLKYLAKQKA 12693
Cdd:PRK10246 744 A---------QRLQKAQAQFDTALQasvFDDQQ---------AFLAALLDEETLTQLEQLKQNLENQRQQAQTLVTQTA 804
|
|
| EnvC |
COG4942 |
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, ... |
12428-12649 |
4.38e-03 |
|
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, cell division, chromosome partitioning];
Pssm-ID: 443969 [Multi-domain] Cd Length: 377 Bit Score: 44.37 E-value: 4.38e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 320544544 12428 QSKALQEQQQELARhcddalatamrmeqasIGQRISNLRAALKTWQGFLQRVTQLSESYEQRVNQLQQEFGAAQKLLDAN 12507
Cdd:COG4942 18 QADAAAEAEAELEQ----------------LQQEIAELEKELAALKKEEKALLKQLAALERRIAALARRIRALEQELAAL 81
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 320544544 12508 SESLPTQPAAIEQLLGSLRAQRVQLGAQVSALESLTvTQEELKECISPHDMKTIrQRNWLLWQQHADLDYQLANLINSIE 12587
Cdd:COG4942 82 EAELAELEKEIAELRAELEAQKEELAELLRALYRLG-RQPPLALLLSPEDFLDA-VRRLQYLKYLAPARREQAEELRADL 159
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|...
gi 320544544 12588 ERLSLLSNyQIRYDRISQWLQRLEQRVEKDADVTAMTNPEQAAKQLEQQVNSEL-QLRDKERE 12649
Cdd:COG4942 160 AELAALRA-ELEAERAELEALLAELEEERAALEALKAERQKLLARLEKELAELAaELAELQQE 221
|
|
| RecN |
COG0497 |
DNA repair ATPase RecN [Replication, recombination and repair]; |
12374-12642 |
4.56e-03 |
|
DNA repair ATPase RecN [Replication, recombination and repair];
Pssm-ID: 440263 [Multi-domain] Cd Length: 555 Bit Score: 44.68 E-value: 4.56e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 320544544 12374 WNAYRQQLAALLDWLRQREAERNALQlryihlkrvpHLKHRLDAMiqQLDQGEQQskALQEQQQELArHCD---DALATA 12450
Cdd:COG0497 167 WRALKKELEELRADEAERARELDLLR----------FQLEELEAA--ALQPGEEE--ELEEERRRLS-NAEklrEALQEA 231
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 320544544 12451 MRM---EQASIGQRISNLRAALktwqgflQRVTQLSESYE---QRVNQLQQEFGAAQKLLDANSESLPTQPAAIEQLLGS 12524
Cdd:COG0497 232 LEAlsgGEGGALDLLGQALRAL-------ERLAEYDPSLAelaERLESALIELEEAASELRRYLDSLEFDPERLEEVEER 304
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 320544544 12525 LraqrvqlgaqvSALESLT----VTQEELkecisphdmktirqrnwllwqqhadLDYQlanliNSIEERLSLLSNYQIRY 12600
Cdd:COG0497 305 L-----------ALLRRLArkygVTVEEL-------------------------LAYA-----EELRAELAELENSDERL 343
|
250 260 270 280
....*....|....*....|....*....|....*....|...
gi 320544544 12601 DRISQWLQRLEQRVEKDAD-VTAMTnpEQAAKQLEQQVNSELQ 12642
Cdd:COG0497 344 EELEAELAEAEAELLEAAEkLSAAR--KKAAKKLEKAVTAELA 384
|
|
| PRK01294 |
PRK01294 |
lipase secretion chaperone; |
12349-12529 |
5.37e-03 |
|
lipase secretion chaperone;
Pssm-ID: 234937 [Multi-domain] Cd Length: 336 Bit Score: 43.90 E-value: 5.37e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 320544544 12349 LTNLHNETLSRIMQR-NGELERRVSG---------WNAYRQQLAAL------------LDWLRQREAERNALQLRY---- 12402
Cdd:PRK01294 96 LSALGELDLAAIDALvEREIAAQLPEpadsqaldlWLRYKAYLSALaqleddgpgkldLQALQQLLDARLALRARFfsdw 175
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 320544544 12403 --------------IHLKRV-----PHL-----KHRLDAMIQQLDQGEQQSKALQEQQQELARHcddalATAMRMEQASi 12458
Cdd:PRK01294 176 eiqaffgeenqyqrYALERLriaqdPSLsdaqkAARLAALEAQLPEDLRAALQESQRQQALLQQ-----LAQLQASGAS- 249
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 320544544 12459 GQRISNLRAALKTWQGfLQRVTQLSE---SYEQRVNQLQQEfgaAQKLLDANSESLPTQPAAIEQllgsLRAQR 12529
Cdd:PRK01294 250 PQELRLMRAQLVGPEA-AQRLEQLDQqraAWQQRYDDYLAQ---RAQILNAAGLSPQDRQAQIAQ----LRQQR 315
|
|
| PRK10905 |
PRK10905 |
cell division protein DamX; Validated |
10703-10830 |
6.82e-03 |
|
cell division protein DamX; Validated
Pssm-ID: 236792 [Multi-domain] Cd Length: 328 Bit Score: 43.77 E-value: 6.82e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 320544544 10703 QQTTPRIPSPTEKSEVEQDIKSVQTSPQHQPKLDETAVQTSLEVQP------DNQENESQTLIVEITETEA--------- 10767
Cdd:PRK10905 82 QGQTPVATDGQQRVEVQGDLNNALTQPQNQQQLNNVAVNSTLPTEPatvapvRNGNASRQTAKTQTAERPAttrparkqa 161
|
90 100 110 120 130 140 150
....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 320544544 10768 -------QTTPRSEEQSVAVEISTTEIQTDVSGQPAETVEISSQTTVTTTIEKELQTTPKDSPRAPEAGS 10830
Cdd:PRK10905 162 viepkkpQATAKTEPKPVAQTPKRTEPAAPVASTKAPAATSTPAPKETATTAPVQTASPAQTTATPAAGG 231
|
|
| CCDC158 |
pfam15921 |
Coiled-coil domain-containing protein 158; CCDC158 is a family of proteins found in eukaryotes. ... |
11276-11877 |
6.99e-03 |
|
Coiled-coil domain-containing protein 158; CCDC158 is a family of proteins found in eukaryotes. The function is not known.
Pssm-ID: 464943 [Multi-domain] Cd Length: 1112 Bit Score: 44.34 E-value: 6.99e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 320544544 11276 QLNDELSTIKQNVVQLERQLSKAEPEPQ----LLqcvdsLKEHVDAVEQVTQQNQVQDSNDLDKWHNFEVLLYNVSSVLA 11351
Cdd:pfam15921 228 ELDTEISYLKGRIFPVEDQLEALKSESQnkieLL-----LQQHQDRIEQLISEHEVEITGLTEKASSARSQANSIQSQLE 302
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 320544544 11352 DLQQSYDlliNQEyplSAKLAQLDELEQQHEAAQQQLAHlcqnarafqrdfpGKKMPQDVHNAFETSKNIANN--IQAER 11429
Cdd:pfam15921 303 IIQEQAR---NQN---SMYMRQLSDLESTVSQLRSELRE-------------AKRMYEDKIEELEKQLVLANSelTEART 363
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 320544544 11430 ERVL----------QLQSLAEEYEQTLKEFT----KITVLADKLVESPI----VSSSLEQLNNEVQKQRKFFVNL-SHCR 11490
Cdd:pfam15921 364 ERDQfsqesgnlddQLQKLLADLHKREKELSlekeQNKRLWDRDTGNSItidhLRRELDDRNMEVQRLEALLKAMkSECQ 443
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 320544544 11491 AMLESLEENID--SETREKHSELHKELyNRATSLLDKASER--SSKLVQAASRWTV--LEKGMRDELQWLQVAQQRVPDL 11564
Cdd:pfam15921 444 GQMERQMAAIQgkNESLEKVSSLTAQL-ESTKEMLRKVVEEltAKKMTLESSERTVsdLTASLQEKERAIEATNAEITKL 522
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 320544544 11565 SAVTSADYDQYttlyQSLSNDISHhyVKMTQLSGIANKLQLlVQAPNLVEETNEALIVLLKL-----REEVALYLHRLLV 11639
Cdd:pfam15921 523 RSRVDLKLQEL----QHLKNEGDH--LRNVQTECEALKLQM-AEKDKVIEILRQQIENMTQLvgqhgRTAGAMQVEKAQL 595
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 320544544 11640 FKEI------WVQYEQQTDKLEAFVREAEQELRNIQIPS-QPTHQPIEHMRQFWEIKA-RFELHNNVRTDtglsfEKSLQ 11711
Cdd:pfam15921 596 EKEIndrrleLQEFKILKDKKDAKIRELEARVSDLELEKvKLVNAGSERLRAVKDIKQeRDQLLNEVKTS-----RNELN 670
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 320544544 11712 VIPLADEMLQRQFHAQLEDrwqavaqaIELIQHNIveclssedvpaDEKLKMVERELQEIYLTMTSMKGVIKNEEELCLY 11791
Cdd:pfam15921 671 SLSEDYEVLKRNFRNKSEE--------METTTNKL-----------KMQLKSAQSELEQTRNTLKSMEGSDGHAMKVAMG 731
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 320544544 11792 IER--------VQVLRTRVGFIGNELGRIGLQEPAIEPEKVgelfSLSHKIST------QIAEELEgasVLRDQLQAIQE 11857
Cdd:pfam15921 732 MQKqitakrgqIDALQSKIQFLEEAMTNANKEKHFLKEEKN----KLSQELSTvateknKMAGELE---VLRSQERRLKE 804
|
650 660
....*....|....*....|
gi 320544544 11858 GISNQRKHQAKISVILDECE 11877
Cdd:pfam15921 805 KVANMEVALDKASLQFAECQ 824
|
|
| PTZ00121 |
PTZ00121 |
MAEBL; Provisional |
1704-1881 |
9.21e-03 |
|
MAEBL; Provisional
Pssm-ID: 173412 [Multi-domain] Cd Length: 2084 Bit Score: 43.98 E-value: 9.21e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 320544544 1704 AEVIKQAEEITQPELQELPAKVESptEPEVISEVVV-EQEQNKPQKPSRKDKKKQKLLENQPETVIETKV--------VE 1774
Cdd:PTZ00121 1718 AEELKKAEEENKIKAEEAKKEAEE--DKKKAEEAKKdEEEKKKIAHLKKEEEKKAEEIRKEKEAVIEEELdeedekrrME 1795
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 320544544 1775 IVKPQQEITEPQTEITEPLNTTSAITTDNNQTVSSEQTTVSDDSGLIKTTVIRTTKivKKISNNQQESQEMNSSTYSDAP 1854
Cdd:PTZ00121 1796 VDKKIKDIFDNFANIIEGGKEGNLVINDSKEMEDSAIKEVADSKNMQLEEADAFEK--HKFNKNNENGEDGNKEADFNKE 1873
|
170 180
....*....|....*....|....*..
gi 320544544 1855 SSLGSyDLAEEAIEPAKIEKSESNSRE 1881
Cdd:PTZ00121 1874 KDLKE-DDEEEIEEADEIEKIDKDDIE 1899
|
|
| |
