|
Name |
Accession |
Description |
Interval |
E-value |
| PSAT_like |
cd00611 |
Phosphoserine aminotransferase (PSAT) family. This family belongs to pyridoxal phosphate (PLP) ... |
18-363 |
0e+00 |
|
Phosphoserine aminotransferase (PSAT) family. This family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). The major group in this CD corresponds to phosphoserine aminotransferase (PSAT). PSAT is active as a dimer and catalyzes the conversion of phosphohydroxypyruvate to phosphoserine.
Pssm-ID: 99736 [Multi-domain] Cd Length: 355 Bit Score: 610.06 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 329299029 18 VLLEIQKQLLDYRGLGISVLEMSHRSSDFAKIIGNTENLVRELLAVPNNYKVIFVQGGGSGQFSAVPLNLIGLKagRSAD 97
Cdd:cd00611 14 VLEQAQKELLDFNGLGMSVMEMSHRSKDFEAIVNEAESDLRELLNIPDNYKVLFLQGGATGQFAAVPLNLLGDK--GTAD 91
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 329299029 98 YVVTGAWSAKAAEEAKKFGT-VNIVHPKL-GSYTKIPDPSTWNLNPDASYVYFCANETVHGVEFDFVPDVKGAVLVCDMS 175
Cdd:cd00611 92 YVVTGAWSAKAAKEAKRYGGvVVIVAAKEeGKYTKIPDVETWDLAPDAAYVHYCSNETIHGVEFDEVPDTGGVPLVADMS 171
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 329299029 176 SNFLSRPVDVSKFGVIFAGAQKNVGSAGVTVVIVRDDLLGFSLRECPSVLDYKVQAGNNSLYNTPPCFSIYVMGMVLEWI 255
Cdd:cd00611 172 SNILSRPIDVSKFGVIYAGAQKNLGPAGVTVVIVRKDLLGKARKITPSMLNYKTHADNNSLYNTPPTFAIYMMGLVLKWL 251
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 329299029 256 KNNGGAAAMEKLSSIKSQMIYEIIDNSQGFYVCPVERQNRSRMNIPFRIgnakGDEALEKRFLDKAVELNMISLKGHRSV 335
Cdd:cd00611 252 KEQGGVEAMEKRNRQKAQLLYDTIDNSNGFYRGPVDKRARSRMNVPFRL----GKEELEKEFLKEAEAAGMIGLKGHRSV 327
|
330 340
....*....|....*....|....*...
gi 329299029 336 GGIRASLYNAVTTEDVEKLAAFMKNFLE 363
Cdd:cd00611 328 GGIRASIYNALSLEGVQALADFMKEFQK 355
|
|
| serC_1 |
TIGR01364 |
phosphoserine aminotransferase; This model represents the common form of the phosphoserine ... |
18-365 |
0e+00 |
|
phosphoserine aminotransferase; This model represents the common form of the phosphoserine aminotransferase SerC. The phosphoserine aminotransferase of the archaeon Methanosarcina barkeri and putative phosphoserine aminotransferase of Mycobacterium tuberculosis are represented by separate models. All are members of the class V aminotransferases (pfam00266). [Amino acid biosynthesis, Serine family]
Pssm-ID: 130431 Cd Length: 349 Bit Score: 606.20 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 329299029 18 VLLEIQKQLLDYRGLGISVLEMSHRSSDFAKIIGNTENLVRELLAVPNNYKVIFVQGGGSGQFSAVPLNLigLKAGRSAD 97
Cdd:TIGR01364 7 VLEQAQKELLNFNGTGMSVMEISHRSKEFEAVANEAESDLRELLNIPDNYEVLFLQGGATGQFAAVPLNL--LAEGKVAD 84
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 329299029 98 YVVTGAWSAKAAEEAKKFGTVNIV-HPKLGSYTKIPDPSTWNLNPDASYVYFCANETVHGVEFDFVPDVKGAVLVCDMSS 176
Cdd:TIGR01364 85 YIVTGAWSKKAAKEAKKYGVVNVVaSGKEGNYTKIPDPSTWEISEDAAYVHYCANETIHGVEFRELPDVKNAPLVADMSS 164
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 329299029 177 NFLSRPVDVSKFGVIFAGAQKNVGSAGVTVVIVRDDLLGFSLRECPSVLDYKVQAGNNSLYNTPPCFSIYVMGMVLEWIK 256
Cdd:TIGR01364 165 NILSRPIDVSKFGLIYAGAQKNIGPAGLTVVIVRKDLLGRASRITPSMLNYKIHAENDSMYNTPPTFAIYVSGLVFKWLK 244
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 329299029 257 NNGGAAAMEKLSSIKSQMIYEIIDNSQGFYVCPVERQNRSRMNIPFRIGNakgdEALEKRFLDKAVELNMISLKGHRSVG 336
Cdd:TIGR01364 245 EQGGVKAIEKRNQAKAQLLYDTIDNSNGFYRNPVDPRNRSRMNVVFTLGN----EELEKRFLKEAEERGLVSLKGHRSVG 320
|
330 340
....*....|....*....|....*....
gi 329299029 337 GIRASLYNAVTTEDVEKLAAFMKNFLEMH 365
Cdd:TIGR01364 321 GMRASIYNAMPLEGVQALVDFMKEFQKKH 349
|
|
| PRK05355 |
PRK05355 |
3-phosphoserine/phosphohydroxythreonine transaminase; |
18-361 |
0e+00 |
|
3-phosphoserine/phosphohydroxythreonine transaminase;
Pssm-ID: 235428 Cd Length: 360 Bit Score: 567.42 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 329299029 18 VLLEIQKQLLDYRGLGISVLEMSHRSSDFAKIIGNTENLVRELLAVPNNYKVIFVQGGGSGQFSAVPLNLigLKAGRSAD 97
Cdd:PRK05355 18 VLEQAQQELLDWNGSGMSVMEISHRSKEFEAVAEEAEADLRELLNIPDNYKVLFLQGGASLQFAMVPMNL--LGGGKKAD 95
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 329299029 98 YVVTGAWSAKAAEEAKKFGTVNIVHP-KLGSYTKIPDPSTWNLNPDASYVYFCANETVHGVEFDFVPDVKGAVLVCDMSS 176
Cdd:PRK05355 96 YVDTGSWSKKAIKEAKKYGEVNVAASsEDDGFTYIPPLDEWQLSDDAAYVHYTSNETIDGTEFHELPDTGDVPLVADMSS 175
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 329299029 177 NFLSRPVDVSKFGVIFAGAQKNVGSAGVTVVIVRDDLLGFSLRECPSVLDYKVQAGNNSLYNTPPCFSIYVMGMVLEWIK 256
Cdd:PRK05355 176 DILSRPIDVSKFGLIYAGAQKNIGPAGLTIVIVREDLLGRALPSIPSMLDYKTHADNDSMYNTPPTFAIYLAGLVFKWLK 255
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 329299029 257 NNGGAAAMEKLSSIKSQMIYEIIDNSqGFYVCPVERQNRSRMNIPFRIgnakGDEALEKRFLDKAVELNMISLKGHRSVG 336
Cdd:PRK05355 256 EQGGVAAMEKRNQEKAALLYDAIDSS-DFYRNPVAPEDRSRMNVPFTL----ADEELDKKFLAEAKAAGLVGLKGHRSVG 330
|
330 340
....*....|....*....|....*
gi 329299029 337 GIRASLYNAVTTEDVEKLAAFMKNF 361
Cdd:PRK05355 331 GMRASIYNAMPLEGVQALVDFMKEF 355
|
|
| SerC |
COG1932 |
Phosphoserine aminotransferase [Coenzyme transport and metabolism, Amino acid transport and ... |
18-365 |
0e+00 |
|
Phosphoserine aminotransferase [Coenzyme transport and metabolism, Amino acid transport and metabolism]; Phosphoserine aminotransferase is part of the Pathway/BioSystem: Serine biosynthesis
Pssm-ID: 441535 Cd Length: 358 Bit Score: 543.90 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 329299029 18 VLLEIQKQLLDYRGLGISVLEMSHRSSDFAKIIGNTENLVRELLAVPNNYKVIFVQGGGSGQFSAVPLNLIGlkAGRSAD 97
Cdd:COG1932 17 VLEQAQAELLDWNGSGMSVMEMSHRSKPFKAIVEEAEADLRELLGIPDGYEVLFLQGGATAQFAMVPMNLLR--GGKKAD 94
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 329299029 98 YVVTGAWSAKAAEEAKKFGTVNIVH-PKLGSYTKIPDPSTWNLNPDASYVYFCANETVHGVEFDFVPDVKGAVLVCDMSS 176
Cdd:COG1932 95 YLVTGEWSKKAIKEAKKYGEVNVVAsSEDDNFGYIPKPEEWQLSPDADYVHYTSNETITGVEFHELPDVGDVPLVADMSS 174
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 329299029 177 NFLSRPVDVSKFGVIFAGAQKNVGSAGVTVVIVRDDLLGFSLRECPSVLDYKVQAGNNSLYNTPPCFSIYVMGMVLEWIK 256
Cdd:COG1932 175 DILSRPVDVSKFGLIYAGAQKNIGPAGLTVVIVRPDLLGRAERAIPSMLDYKTHADNDSMYNTPPTFAIYLAGLVLKWLK 254
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 329299029 257 NNGGAAAMEKLSSIKSQMIYEIIDNSqGFYVCPVERQNRSRMNIPFRIgnakGDEALEKRFLDKAVELNMISLKGHRSVG 336
Cdd:COG1932 255 EQGGLAAMEKRNAEKAALLYDWIDAS-DFYTNPVDPEDRSRMNVTFDL----ADEELDAAFLAEAKAAGLVGLKGHRSVG 329
|
330 340
....*....|....*....|....*....
gi 329299029 337 GIRASLYNAVTTEDVEKLAAFMKNFLEMH 365
Cdd:COG1932 330 GMRASIYNAMPLEGVEALVDFMDEFERRH 358
|
|
| Aminotran_5 |
pfam00266 |
Aminotransferase class-V; This domain is found in amino transferases, and other enzymes ... |
18-354 |
2.09e-81 |
|
Aminotransferase class-V; This domain is found in amino transferases, and other enzymes including cysteine desulphurase EC:4.4.1.-.
Pssm-ID: 425567 [Multi-domain] Cd Length: 368 Bit Score: 252.94 E-value: 2.09e-81
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 329299029 18 VLLEIQKQLLDYRGLGISvlEMSHRSSDFAKIIGNTENLVRELLAVPNNYKVIFVQGGGSgQFSAVPLNLI-GLKAGRSA 96
Cdd:pfam00266 15 VLDAIQEYYTDYNGNVHR--GVHTLGKEATQAYEEAREKVAEFINAPSNDEIIFTSGTTE-AINLVALSLGrSLKPGDEI 91
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 329299029 97 DYVVTGAWSAK-AAEEAKKFGTVNIVHPKL---GSYTkiPDPSTWNLNPDASYVYFCANETVHGVEFDfVPDV------K 166
Cdd:pfam00266 92 VITEMEHHANLvPWQELAKRTGARVRVLPLdedGLLD--LDELEKLITPKTKLVAITHVSNVTGTIQP-VPEIgklahqY 168
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 329299029 167 GAVLVCDMSSNFLSRPVDVSKFGV--IFAGAQKNVGSAGVTVVIVRDDLLGF--------SLRECPSvLDYKVQAGNNSL 236
Cdd:pfam00266 169 GALVLVDAAQAIGHRPIDVQKLGVdfLAFSGHKLYGPTGIGVLYGRRDLLEKmppllgggGMIETVS-LQESTFADAPWK 247
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 329299029 237 YN--TPPCFSIYVMGMVLEWIkNNGGAAAMEKLSSIKSQMIYEIIDNSQGFYVCPVERqNRSRMNIPFRIGNAkgdeALE 314
Cdd:pfam00266 248 FEagTPNIAGIIGLGAALEYL-SEIGLEAIEKHEHELAQYLYERLLSLPGIRLYGPER-RASIISFNFKGVHP----HDV 321
|
330 340 350 360
....*....|....*....|....*....|....*....|....*..
gi 329299029 315 KRFLDK-AVELN------MISLKGHRSVGGIRASLYNAVTTEDVEKL 354
Cdd:pfam00266 322 ATLLDEsGIAVRsghhcaQPLMVRLGLGGTVRASFYIYNTQEDVDRL 368
|
|
| |
|
Name |
Accession |
Description |
Interval |
E-value |
| PSAT_like |
cd00611 |
Phosphoserine aminotransferase (PSAT) family. This family belongs to pyridoxal phosphate (PLP) ... |
18-363 |
0e+00 |
|
Phosphoserine aminotransferase (PSAT) family. This family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). The major group in this CD corresponds to phosphoserine aminotransferase (PSAT). PSAT is active as a dimer and catalyzes the conversion of phosphohydroxypyruvate to phosphoserine.
Pssm-ID: 99736 [Multi-domain] Cd Length: 355 Bit Score: 610.06 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 329299029 18 VLLEIQKQLLDYRGLGISVLEMSHRSSDFAKIIGNTENLVRELLAVPNNYKVIFVQGGGSGQFSAVPLNLIGLKagRSAD 97
Cdd:cd00611 14 VLEQAQKELLDFNGLGMSVMEMSHRSKDFEAIVNEAESDLRELLNIPDNYKVLFLQGGATGQFAAVPLNLLGDK--GTAD 91
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 329299029 98 YVVTGAWSAKAAEEAKKFGT-VNIVHPKL-GSYTKIPDPSTWNLNPDASYVYFCANETVHGVEFDFVPDVKGAVLVCDMS 175
Cdd:cd00611 92 YVVTGAWSAKAAKEAKRYGGvVVIVAAKEeGKYTKIPDVETWDLAPDAAYVHYCSNETIHGVEFDEVPDTGGVPLVADMS 171
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 329299029 176 SNFLSRPVDVSKFGVIFAGAQKNVGSAGVTVVIVRDDLLGFSLRECPSVLDYKVQAGNNSLYNTPPCFSIYVMGMVLEWI 255
Cdd:cd00611 172 SNILSRPIDVSKFGVIYAGAQKNLGPAGVTVVIVRKDLLGKARKITPSMLNYKTHADNNSLYNTPPTFAIYMMGLVLKWL 251
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 329299029 256 KNNGGAAAMEKLSSIKSQMIYEIIDNSQGFYVCPVERQNRSRMNIPFRIgnakGDEALEKRFLDKAVELNMISLKGHRSV 335
Cdd:cd00611 252 KEQGGVEAMEKRNRQKAQLLYDTIDNSNGFYRGPVDKRARSRMNVPFRL----GKEELEKEFLKEAEAAGMIGLKGHRSV 327
|
330 340
....*....|....*....|....*...
gi 329299029 336 GGIRASLYNAVTTEDVEKLAAFMKNFLE 363
Cdd:cd00611 328 GGIRASIYNALSLEGVQALADFMKEFQK 355
|
|
| serC_1 |
TIGR01364 |
phosphoserine aminotransferase; This model represents the common form of the phosphoserine ... |
18-365 |
0e+00 |
|
phosphoserine aminotransferase; This model represents the common form of the phosphoserine aminotransferase SerC. The phosphoserine aminotransferase of the archaeon Methanosarcina barkeri and putative phosphoserine aminotransferase of Mycobacterium tuberculosis are represented by separate models. All are members of the class V aminotransferases (pfam00266). [Amino acid biosynthesis, Serine family]
Pssm-ID: 130431 Cd Length: 349 Bit Score: 606.20 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 329299029 18 VLLEIQKQLLDYRGLGISVLEMSHRSSDFAKIIGNTENLVRELLAVPNNYKVIFVQGGGSGQFSAVPLNLigLKAGRSAD 97
Cdd:TIGR01364 7 VLEQAQKELLNFNGTGMSVMEISHRSKEFEAVANEAESDLRELLNIPDNYEVLFLQGGATGQFAAVPLNL--LAEGKVAD 84
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 329299029 98 YVVTGAWSAKAAEEAKKFGTVNIV-HPKLGSYTKIPDPSTWNLNPDASYVYFCANETVHGVEFDFVPDVKGAVLVCDMSS 176
Cdd:TIGR01364 85 YIVTGAWSKKAAKEAKKYGVVNVVaSGKEGNYTKIPDPSTWEISEDAAYVHYCANETIHGVEFRELPDVKNAPLVADMSS 164
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 329299029 177 NFLSRPVDVSKFGVIFAGAQKNVGSAGVTVVIVRDDLLGFSLRECPSVLDYKVQAGNNSLYNTPPCFSIYVMGMVLEWIK 256
Cdd:TIGR01364 165 NILSRPIDVSKFGLIYAGAQKNIGPAGLTVVIVRKDLLGRASRITPSMLNYKIHAENDSMYNTPPTFAIYVSGLVFKWLK 244
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 329299029 257 NNGGAAAMEKLSSIKSQMIYEIIDNSQGFYVCPVERQNRSRMNIPFRIGNakgdEALEKRFLDKAVELNMISLKGHRSVG 336
Cdd:TIGR01364 245 EQGGVKAIEKRNQAKAQLLYDTIDNSNGFYRNPVDPRNRSRMNVVFTLGN----EELEKRFLKEAEERGLVSLKGHRSVG 320
|
330 340
....*....|....*....|....*....
gi 329299029 337 GIRASLYNAVTTEDVEKLAAFMKNFLEMH 365
Cdd:TIGR01364 321 GMRASIYNAMPLEGVQALVDFMKEFQKKH 349
|
|
| PRK05355 |
PRK05355 |
3-phosphoserine/phosphohydroxythreonine transaminase; |
18-361 |
0e+00 |
|
3-phosphoserine/phosphohydroxythreonine transaminase;
Pssm-ID: 235428 Cd Length: 360 Bit Score: 567.42 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 329299029 18 VLLEIQKQLLDYRGLGISVLEMSHRSSDFAKIIGNTENLVRELLAVPNNYKVIFVQGGGSGQFSAVPLNLigLKAGRSAD 97
Cdd:PRK05355 18 VLEQAQQELLDWNGSGMSVMEISHRSKEFEAVAEEAEADLRELLNIPDNYKVLFLQGGASLQFAMVPMNL--LGGGKKAD 95
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 329299029 98 YVVTGAWSAKAAEEAKKFGTVNIVHP-KLGSYTKIPDPSTWNLNPDASYVYFCANETVHGVEFDFVPDVKGAVLVCDMSS 176
Cdd:PRK05355 96 YVDTGSWSKKAIKEAKKYGEVNVAASsEDDGFTYIPPLDEWQLSDDAAYVHYTSNETIDGTEFHELPDTGDVPLVADMSS 175
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 329299029 177 NFLSRPVDVSKFGVIFAGAQKNVGSAGVTVVIVRDDLLGFSLRECPSVLDYKVQAGNNSLYNTPPCFSIYVMGMVLEWIK 256
Cdd:PRK05355 176 DILSRPIDVSKFGLIYAGAQKNIGPAGLTIVIVREDLLGRALPSIPSMLDYKTHADNDSMYNTPPTFAIYLAGLVFKWLK 255
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 329299029 257 NNGGAAAMEKLSSIKSQMIYEIIDNSqGFYVCPVERQNRSRMNIPFRIgnakGDEALEKRFLDKAVELNMISLKGHRSVG 336
Cdd:PRK05355 256 EQGGVAAMEKRNQEKAALLYDAIDSS-DFYRNPVAPEDRSRMNVPFTL----ADEELDKKFLAEAKAAGLVGLKGHRSVG 330
|
330 340
....*....|....*....|....*
gi 329299029 337 GIRASLYNAVTTEDVEKLAAFMKNF 361
Cdd:PRK05355 331 GMRASIYNAMPLEGVQALVDFMKEF 355
|
|
| SerC |
COG1932 |
Phosphoserine aminotransferase [Coenzyme transport and metabolism, Amino acid transport and ... |
18-365 |
0e+00 |
|
Phosphoserine aminotransferase [Coenzyme transport and metabolism, Amino acid transport and metabolism]; Phosphoserine aminotransferase is part of the Pathway/BioSystem: Serine biosynthesis
Pssm-ID: 441535 Cd Length: 358 Bit Score: 543.90 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 329299029 18 VLLEIQKQLLDYRGLGISVLEMSHRSSDFAKIIGNTENLVRELLAVPNNYKVIFVQGGGSGQFSAVPLNLIGlkAGRSAD 97
Cdd:COG1932 17 VLEQAQAELLDWNGSGMSVMEMSHRSKPFKAIVEEAEADLRELLGIPDGYEVLFLQGGATAQFAMVPMNLLR--GGKKAD 94
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 329299029 98 YVVTGAWSAKAAEEAKKFGTVNIVH-PKLGSYTKIPDPSTWNLNPDASYVYFCANETVHGVEFDFVPDVKGAVLVCDMSS 176
Cdd:COG1932 95 YLVTGEWSKKAIKEAKKYGEVNVVAsSEDDNFGYIPKPEEWQLSPDADYVHYTSNETITGVEFHELPDVGDVPLVADMSS 174
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 329299029 177 NFLSRPVDVSKFGVIFAGAQKNVGSAGVTVVIVRDDLLGFSLRECPSVLDYKVQAGNNSLYNTPPCFSIYVMGMVLEWIK 256
Cdd:COG1932 175 DILSRPVDVSKFGLIYAGAQKNIGPAGLTVVIVRPDLLGRAERAIPSMLDYKTHADNDSMYNTPPTFAIYLAGLVLKWLK 254
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 329299029 257 NNGGAAAMEKLSSIKSQMIYEIIDNSqGFYVCPVERQNRSRMNIPFRIgnakGDEALEKRFLDKAVELNMISLKGHRSVG 336
Cdd:COG1932 255 EQGGLAAMEKRNAEKAALLYDWIDAS-DFYTNPVDPEDRSRMNVTFDL----ADEELDAAFLAEAKAAGLVGLKGHRSVG 329
|
330 340
....*....|....*....|....*....
gi 329299029 337 GIRASLYNAVTTEDVEKLAAFMKNFLEMH 365
Cdd:COG1932 330 GMRASIYNAMPLEGVEALVDFMDEFERRH 358
|
|
| PLN02452 |
PLN02452 |
phosphoserine transaminase |
18-366 |
1.13e-177 |
|
phosphoserine transaminase
Pssm-ID: 178071 Cd Length: 365 Bit Score: 497.68 E-value: 1.13e-177
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 329299029 18 VLLEIQKQLLDYRGLGISVLEMSHRSSDFAKIIGNTENLVRELLAVPNNYKVIFVQGGGSGQFSAVPLNLIglKAGRSAD 97
Cdd:PLN02452 22 VLAKAQAELYNWEGSGMSVMEMSHRGKEFLSIIQKAEADLRELLDIPDNYEVLFLQGGASTQFAAIPLNLC--KPGDKAD 99
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 329299029 98 YVVTGAWSAKAAEEAKKFGTVNIVHP-KLGSYTKIPDPSTWNLNPDASYVYFCANETVHGVEFDFVPDVKGAVLVCDMSS 176
Cdd:PLN02452 100 FVVTGSWSKKAAKEAKKYCKTNVIASgKDEKYTKIPSVSEWELTPDAKFVHICANETIHGVEFKDYPDVGNVPLVADMSS 179
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 329299029 177 NFLSRPVDVSKFGVIFAGAQKNVGSAGVTVVIVRDDLLGFSLRECPSVLDYKVQAGNNSLYNTPPCFSIYVMGMVLEWIK 256
Cdd:PLN02452 180 NFLSKPVDVSKYGVIYAGAQKNVGPSGVTIVIIRKDLIGNARPITPGMLDYKIHAENDSLYNTPPCFGIYMCGLVFEDLL 259
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 329299029 257 NNGGAAAMEKLSSIKSQMIYEIIDNSQGFYVCPVERQNRSRMNIPFRIgnakGDEALEKRFLDKAVELNMISLKGHRSVG 336
Cdd:PLN02452 260 AQGGLKAMEKRNIRKADLLYDAIDESNGFYVCPVEKSVRSLMNVPFTL----GGSELEAEFVKEAAKAGMVQLKGHRSVG 335
|
330 340 350
....*....|....*....|....*....|
gi 329299029 337 GIRASLYNAVTTEDVEKLAAFMKNFLEMHQ 366
Cdd:PLN02452 336 GMRASIYNAMPLAGVEKLVAFMKDFQAKHA 365
|
|
| PRK12462 |
PRK12462 |
phosphoserine aminotransferase; Provisional |
18-361 |
1.85e-121 |
|
phosphoserine aminotransferase; Provisional
Pssm-ID: 183540 Cd Length: 364 Bit Score: 354.89 E-value: 1.85e-121
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 329299029 18 VLLEIQKQLLDYRGLGISVLEMSHRSSDFAKIIGNTENLVRELLAVPNNYKVIFVQGGGSGQFSAVPLNLIgLKAGRSAD 97
Cdd:PRK12462 19 VLEQVRQAVVELPETGLSVLGMSHRSSWFSSLLAQAEADLRDLLGIPDEYGVVFLQGGSSLQFSMIPMNFS-RPGAAAPE 97
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 329299029 98 YVVTGAWSAKAAEEAKKFGTVNIV-HPKLGSYTKIPDPSTWNLNPDASYVYFCANETVHGVEFDFVPDVKGAVLVCDMSS 176
Cdd:PRK12462 98 YVTTGYWSRKAIGEASRVAAMRVVwDGAASGYRTLPSLAELDWDARAPFRHYVSNETVEGLQFPDAAGLPDSPLIADMSS 177
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 329299029 177 NFLSRPVDVSKFGVIFAGAQKNVGSAGVTVVIVRDDLLGFSLRECPSVLDYKVQAGNNSLYNTPPCFSIYVMGMVLEWIK 256
Cdd:PRK12462 178 DFMSRPFDVEAYGMVYAHAQKNLGPAGVTVAIIRRALLERVPDTLPPMLDFRTHVEHRSNYNTPPVFAIYVMALVLRWIR 257
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 329299029 257 NN-GGAAAMEKLSSIKSQMIYEIIDNSQGFYVCPVERQNRSRMNIPFRIGNAkgdeALEKRFLDKAVELNMISLKGHRSV 335
Cdd:PRK12462 258 DEiGGVHAMRDINARKAAMLYATLDALNEVIDCHAHRAARSTMNVAFRFRQP----RLDTLFKEQSTEAGFCGLSGHRSI 333
|
330 340
....*....|....*....|....*.
gi 329299029 336 GGIRASLYNAVTTEDVEKLAAFMKNF 361
Cdd:PRK12462 334 GGIRASLYNAVSEQAVSRLCAFLKDF 359
|
|
| Aminotran_5 |
pfam00266 |
Aminotransferase class-V; This domain is found in amino transferases, and other enzymes ... |
18-354 |
2.09e-81 |
|
Aminotransferase class-V; This domain is found in amino transferases, and other enzymes including cysteine desulphurase EC:4.4.1.-.
Pssm-ID: 425567 [Multi-domain] Cd Length: 368 Bit Score: 252.94 E-value: 2.09e-81
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 329299029 18 VLLEIQKQLLDYRGLGISvlEMSHRSSDFAKIIGNTENLVRELLAVPNNYKVIFVQGGGSgQFSAVPLNLI-GLKAGRSA 96
Cdd:pfam00266 15 VLDAIQEYYTDYNGNVHR--GVHTLGKEATQAYEEAREKVAEFINAPSNDEIIFTSGTTE-AINLVALSLGrSLKPGDEI 91
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 329299029 97 DYVVTGAWSAK-AAEEAKKFGTVNIVHPKL---GSYTkiPDPSTWNLNPDASYVYFCANETVHGVEFDfVPDV------K 166
Cdd:pfam00266 92 VITEMEHHANLvPWQELAKRTGARVRVLPLdedGLLD--LDELEKLITPKTKLVAITHVSNVTGTIQP-VPEIgklahqY 168
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 329299029 167 GAVLVCDMSSNFLSRPVDVSKFGV--IFAGAQKNVGSAGVTVVIVRDDLLGF--------SLRECPSvLDYKVQAGNNSL 236
Cdd:pfam00266 169 GALVLVDAAQAIGHRPIDVQKLGVdfLAFSGHKLYGPTGIGVLYGRRDLLEKmppllgggGMIETVS-LQESTFADAPWK 247
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 329299029 237 YN--TPPCFSIYVMGMVLEWIkNNGGAAAMEKLSSIKSQMIYEIIDNSQGFYVCPVERqNRSRMNIPFRIGNAkgdeALE 314
Cdd:pfam00266 248 FEagTPNIAGIIGLGAALEYL-SEIGLEAIEKHEHELAQYLYERLLSLPGIRLYGPER-RASIISFNFKGVHP----HDV 321
|
330 340 350 360
....*....|....*....|....*....|....*....|....*..
gi 329299029 315 KRFLDK-AVELN------MISLKGHRSVGGIRASLYNAVTTEDVEKL 354
Cdd:pfam00266 322 ATLLDEsGIAVRsghhcaQPLMVRLGLGGTVRASFYIYNTQEDVDRL 368
|
|
| PRK03080 |
PRK03080 |
phosphoserine transaminase; |
32-282 |
1.19e-14 |
|
phosphoserine transaminase;
Pssm-ID: 235103 Cd Length: 378 Bit Score: 74.45 E-value: 1.19e-14
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 329299029 32 LGISVLEMSHRSSDFAKIIGNTENLVRELLAVPNNYKVIFVQGGGSGQFSAVPLNLIGlkaGRSADYVVTGAWSAKAAEE 111
Cdd:PRK03080 32 LADALLGRSHRQKPVKALLKRVIEGTRELLSLPEGYEVGIVPGSDTGAWEMALWSLLG---ARRVDHLAWESFGSKWATD 108
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 329299029 112 AKKfgtvnivHPKLG-------SYTKIPDPSTwnLNPDASYVyFCANETVHGVE---FDFVPDVKGAVLVCDMSSNFLSR 181
Cdd:PRK03080 109 VVK-------QLKLEdprvleaDYGSLPDLSA--VDFDRDVV-FTWNGTTTGVRvpvARWIGADREGLTICDATSAAFAL 178
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 329299029 182 PVDVSKFGVIFAGAQKNVGSAGVtvvivrddlLGFSL---------------RECPSVLDY--KVQAGNNSL----YNTP 240
Cdd:PRK03080 179 PLDWSKLDVYTFSWQKVLGGEGG---------HGMAIlspraverlesytpaRPIPKFFRLtkGGKAIENSFkgqtINTP 249
|
250 260 270 280
....*....|....*....|....*....|....*....|..
gi 329299029 241 PCFSIYVMGMVLEWIKNNGGAAAMEKLSSIKSQMIYEIIDNS 282
Cdd:PRK03080 250 SMLTVEDYLDQLDWANSIGGLDALIARTAANASVLYDWAEKT 291
|
|
| AAT_I |
cd01494 |
Aspartate aminotransferase (AAT) superfamily (fold type I) of pyridoxal phosphate (PLP) ... |
61-210 |
1.76e-08 |
|
Aspartate aminotransferase (AAT) superfamily (fold type I) of pyridoxal phosphate (PLP)-dependent enzymes. PLP combines with an alpha-amino acid to form a compound called a Schiff base or aldimine intermediate, which depending on the reaction, is the substrate in four kinds of reactions (1) transamination (movement of amino groups), (2) racemization (redistribution of enantiomers), (3) decarboxylation (removing COOH groups), and (4) various side-chain reactions depending on the enzyme involved. Pyridoxal phosphate (PLP) dependent enzymes were previously classified into alpha, beta and gamma classes, based on the chemical characteristics (carbon atom involved) of the reaction they catalyzed. The availability of several structures allowed a comprehensive analysis of the evolutionary classification of PLP dependent enzymes, and it was found that the functional classification did not always agree with the evolutionary history of these enzymes. Structure and sequence analysis has revealed that the PLP dependent enzymes can be classified into four major groups of different evolutionary origin: aspartate aminotransferase superfamily (fold type I), tryptophan synthase beta superfamily (fold type II), alanine racemase superfamily (fold type III), and D-amino acid superfamily (fold type IV) and Glycogen phophorylase family (fold type V).
Pssm-ID: 99742 [Multi-domain] Cd Length: 170 Bit Score: 53.54 E-value: 1.76e-08
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 329299029 61 LAVPNNYKVIFVqGGGSGQFSAVPLNLigLKAGRSADYVVTGAWSAKAAEEAKKFGTVNIVHPKLGSYTKIP--DPSTWN 138
Cdd:cd01494 12 LLQPGNDKAVFV-PSGTGANEAALLAL--LGPGDEVIVDANGHGSRYWVAAELAGAKPVPVPVDDAGYGGLDvaILEELK 88
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 329299029 139 LNPDASYVYFCANETVHGV-----EFDFVPDVKGAVLVCDMSSNFLSRP-----VDVSKFGVIFAGAQKNVGSAGVTVVI 208
Cdd:cd01494 89 AKPNVALIVITPNTTSGGVlvplkEIRKIAKEYGILLLVDAASAGGASPapgvlIPEGGADVVTFSLHKNLGGEGGGVVI 168
|
..
gi 329299029 209 VR 210
Cdd:cd01494 169 VK 170
|
|
| AGAT_like |
cd06451 |
Alanine-glyoxylate aminotransferase (AGAT) family. This family belongs to pyridoxal phosphate ... |
39-207 |
1.63e-05 |
|
Alanine-glyoxylate aminotransferase (AGAT) family. This family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). The major groups in this CD correspond to alanine-glyoxylate aminotransferase (AGAT), serine-glyoxylate aminotransferase (SGAT), and 3-hydroxykynurenine transaminase (HKT). AGAT is a homodimeric protein, which catalyses the transamination of glyoxylate to glycine, and SGAT converts serine and glyoxylate to hydroxypyruvate and glycine. HKT catalyzes the PLP-dependent transamination of 3-hydroxykynurenine, a potentially toxic metabolite of the kynurenine pathway.
Pssm-ID: 99744 [Multi-domain] Cd Length: 356 Bit Score: 46.13 E-value: 1.63e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 329299029 39 MSHRSSDFAKIIGNTENLVRELLAvPNNYKVIFVQGGGSGQFSAVPLNLIglKAGRSADYVVTGAWSAKAAEEAKKFGT- 117
Cdd:cd06451 23 LGHRSPEFLALMDEILEGLRYVFQ-TENGLTFLLSGSGTGAMEAALSNLL--EPGDKVLVGVNGVFGDRWADMAERYGAd 99
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 329299029 118 VNIVHPKLGSYTKIPDPSTWNLNPDASYVYFCANETVHGVEFDfVPDVKGAV------LVCDMSSNFLSRPVDVSKFGV- 190
Cdd:cd06451 100 VDVVEKPWGEAVSPEEIAEALEQHDIKAVTLTHNETSTGVLNP-LEGIGALAkkhdalLIVDAVSSLGGEPFRMDEWGVd 178
|
170
....*....|....*....
gi 329299029 191 -IFAGAQKNVGS-AGVTVV 207
Cdd:cd06451 179 vAYTGSQKALGApPGLGPI 197
|
|
| |
