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Conserved domains on  [gi|357527439|ref|NP_001239466|]
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cip1-interacting zinc finger protein isoform 4 [Mus musculus]

Protein Classification

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
PHA03247 super family cl33720
large tegument protein UL36; Provisional
 46-413 5.24e-10

large tegument protein UL36; Provisional


The actual alignment was detected with superfamily member PHA03247:

Pssm-ID: 223021 [Multi-domain]  Cd Length: 3151  Bit Score: 63.42  E-value: 5.24e-10
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 357527439   46 PPQASLSIPVSRGLPQQSSPQQLLSLQGLHSTSLLNGPMLQRALLLQQLQGLDQFAMPPATYDGASLTMPTATLGNLRAF 125
Cdd:PHA03247 2619 PDTHAPDPPPPSPSPAANEPDPHPPPTVPPPERPRDDPAPGRVSRPRRARRLGRAAQASSPPQRPRRRAARPTVGSLTSL 2698

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 357527439  126 NVTAPSLAAPSLTPPQMVTPNLQQFFPQATRQSLLGPP--------------PVGVPINPSQLNHSGRNTQKQARTPSST 191
Cdd:PHA03247 2699 ADPPPPPPTPEPAPHALVSATPLPPGPAAARQASPALPaapappavpagpatPGGPARPARPPTTAGPPAPAPPAAPAAG 2778

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 357527439  192 TPNRKTVPledREDPTEGSEEATELQMDTCEDQDSLVGPDSMLSEPQVPE-PEPFETLEPPAKRCRSSEESTEKGPTGQP 270
Cdd:PHA03247 2779 PPRRLTRP---AVASLSESRESLPSPWDPADPPAAVLAPAAALPPAASPAgPLPPPTSAQPTAPPPPPGPPPPSLPLGGS 2855

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 357527439  271 QARVQPQTQMTAPKQTQTPDRLPEPPEVQMLPRIQPQAlqiQTQPkllrQAQTQTSPEHLAPQQDQVPTQAQSQEQTSEK 350
Cdd:PHA03247 2856 VAPGGDVRRRPPSRSPAAKPAAPARPPVRRLARPAVSR---STES----FALPPDQPERPPQPQAPPPPQPQPQPPPPPQ 2928

                         330       340       350       360       370       380
                  ....*....|....*....|....*....|....*....|....*....|....*....|...
gi 357527439  351 TQDQPQTWPQGSVPPPEQAsGPACATEPQLSSHAAEAGSDPDKALPEPVSAQSSEDRSREASA 413
Cdd:PHA03247 2929 PQPPPPPPPRPQPPLAPTT-DPAGAGEPSGAVPQPWLGALVPGRVAVPRFRVPQPAPSREAPA 2990
zf-C2H2_jaz pfam12171
Zinc-finger double-stranded RNA-binding; This domain family is found in archaea and eukaryotes, ...
 576-600 1.66e-05

Zinc-finger double-stranded RNA-binding; This domain family is found in archaea and eukaryotes, and is approximately 30 amino acids in length. The mammalian members of this group occur multiple times along the protein, joined by flexible linkers, and are referred to as JAZ - dsRNA-binding ZF protein - zinc-fingers. The JAZ proteins are expressed in all tissues tested and localize in the nucleus, particularly the nucleolus. JAZ preferentially binds to double-stranded (ds) RNA or RNA/DNA hybrids rather than DNA. In addition to binding double-stranded RNA, these zinc-fingers are required for nucleolar localization.


:

Pssm-ID: 432381 [Multi-domain]  Cd Length: 27  Bit Score: 42.16  E-value: 1.66e-05
                          10        20
                  ....*....|....*....|....*
gi 357527439  576 FCTICNRYFKTPRKFVEHVKSQGHK 600
Cdd:pfam12171   3 YCVLCDKYFKSENALQNHLKSKKHK 27
ZnF_U1 smart00451
U1-like zinc finger; Family of C2H2-type zinc fingers, present in matrin, U1 small nuclear ...
 692-725 1.57e-03

U1-like zinc finger; Family of C2H2-type zinc fingers, present in matrin, U1 small nuclear ribonucleoprotein C and other RNA-binding proteins.


:

Pssm-ID: 197732 [Multi-domain]  Cd Length: 35  Bit Score: 36.85  E-value: 1.57e-03
                           10        20        30
                   ....*....|....*....|....*....|....
gi 357527439   692 GYVCQICHKFYDSNSELRlSHCKSLAHFENLQKY 725
Cdd:smart00451   3 GFYCKLCNVTFTDEISVE-AHLKGKKHKKNVKKR 35
GIY-YIG_SF super family cl15257
GIY-YIG nuclease domain superfamily; The GIY-YIG nuclease domain superfamily includes a large ...
 545-612 2.65e-03

GIY-YIG nuclease domain superfamily; The GIY-YIG nuclease domain superfamily includes a large and diverse group of proteins involved in many cellular processes, such as class I homing GIY-YIG family endonucleases, prokaryotic nucleotide excision repair proteins UvrC and Cho, type II restriction enzymes, the endonuclease/reverse transcriptase of eukaryotic retrotransposable elements, and a family of eukaryotic enzymes that repair stalled replication forks. All of these members contain a conserved GIY-YIG nuclease domain that may serve as a scaffold for the coordination of a divalent metal ion required for catalysis of the phosphodiester bond cleavage. By combining with different specificity, targeting, or other domains, the GIY-YIG nucleases may perform different functions.


The actual alignment was detected with superfamily member cd10442:

Pssm-ID: 472790  Cd Length: 92  Bit Score: 37.73  E-value: 2.65e-03
                         10        20        30        40        50        60        70
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 357527439 545 WCNTCQVYYVGDLIQ--HRRTQEHKVAKQSlrpfcticNRYFKTPrkFVEHVKSQGHKDKAQELKTLEKE 612
Cdd:cd10442    6 PCPKCGLVYIGETKRplRERMKEHRRAIRL--------SGTKKSA--VAKHFNEEGHSIDSDRVRILDKE 65
 
Name Accession Description Interval E-value
PHA03247 PHA03247
large tegument protein UL36; Provisional
 46-413 5.24e-10

large tegument protein UL36; Provisional


Pssm-ID: 223021 [Multi-domain]  Cd Length: 3151  Bit Score: 63.42  E-value: 5.24e-10
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 357527439   46 PPQASLSIPVSRGLPQQSSPQQLLSLQGLHSTSLLNGPMLQRALLLQQLQGLDQFAMPPATYDGASLTMPTATLGNLRAF 125
Cdd:PHA03247 2619 PDTHAPDPPPPSPSPAANEPDPHPPPTVPPPERPRDDPAPGRVSRPRRARRLGRAAQASSPPQRPRRRAARPTVGSLTSL 2698

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 357527439  126 NVTAPSLAAPSLTPPQMVTPNLQQFFPQATRQSLLGPP--------------PVGVPINPSQLNHSGRNTQKQARTPSST 191
Cdd:PHA03247 2699 ADPPPPPPTPEPAPHALVSATPLPPGPAAARQASPALPaapappavpagpatPGGPARPARPPTTAGPPAPAPPAAPAAG 2778

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 357527439  192 TPNRKTVPledREDPTEGSEEATELQMDTCEDQDSLVGPDSMLSEPQVPE-PEPFETLEPPAKRCRSSEESTEKGPTGQP 270
Cdd:PHA03247 2779 PPRRLTRP---AVASLSESRESLPSPWDPADPPAAVLAPAAALPPAASPAgPLPPPTSAQPTAPPPPPGPPPPSLPLGGS 2855

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 357527439  271 QARVQPQTQMTAPKQTQTPDRLPEPPEVQMLPRIQPQAlqiQTQPkllrQAQTQTSPEHLAPQQDQVPTQAQSQEQTSEK 350
Cdd:PHA03247 2856 VAPGGDVRRRPPSRSPAAKPAAPARPPVRRLARPAVSR---STES----FALPPDQPERPPQPQAPPPPQPQPQPPPPPQ 2928

                         330       340       350       360       370       380
                  ....*....|....*....|....*....|....*....|....*....|....*....|...
gi 357527439  351 TQDQPQTWPQGSVPPPEQAsGPACATEPQLSSHAAEAGSDPDKALPEPVSAQSSEDRSREASA 413
Cdd:PHA03247 2929 PQPPPPPPPRPQPPLAPTT-DPAGAGEPSGAVPQPWLGALVPGRVAVPRFRVPQPAPSREAPA 2990
zf-C2H2_jaz pfam12171
Zinc-finger double-stranded RNA-binding; This domain family is found in archaea and eukaryotes, ...
 576-600 1.66e-05

Zinc-finger double-stranded RNA-binding; This domain family is found in archaea and eukaryotes, and is approximately 30 amino acids in length. The mammalian members of this group occur multiple times along the protein, joined by flexible linkers, and are referred to as JAZ - dsRNA-binding ZF protein - zinc-fingers. The JAZ proteins are expressed in all tissues tested and localize in the nucleus, particularly the nucleolus. JAZ preferentially binds to double-stranded (ds) RNA or RNA/DNA hybrids rather than DNA. In addition to binding double-stranded RNA, these zinc-fingers are required for nucleolar localization.


Pssm-ID: 432381 [Multi-domain]  Cd Length: 27  Bit Score: 42.16  E-value: 1.66e-05
                          10        20
                  ....*....|....*....|....*
gi 357527439  576 FCTICNRYFKTPRKFVEHVKSQGHK 600
Cdd:pfam12171   3 YCVLCDKYFKSENALQNHLKSKKHK 27
PAT1 pfam09770
Topoisomerase II-associated protein PAT1; Members of this family are necessary for accurate ...
 156-407 7.23e-04

Topoisomerase II-associated protein PAT1; Members of this family are necessary for accurate chromosome transmission during cell division.


Pssm-ID: 401645 [Multi-domain]  Cd Length: 846  Bit Score: 43.10  E-value: 7.23e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 357527439  156 RQSLLGPPPVGVPINPSQLNHSGRNTQKQARTPSSTTPNRKTvPLEDREDPtegsEEATELQMDTcedqdSL--VGPDSM 233
Cdd:pfam09770 101 RFNRQQPAARAAQSSAQPPASSLPQYQYASQQSQQPSKPVRT-GYEKYKEP----EPIPDLQVDA-----SLwgVAPKKA 170

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 357527439  234 LSEPQVPEPEPFETLEPPAKRCRSSEESTEKGPTGQPQARVQPQT--------QMTAPKQTQTPDRLPEPPEVQMLPRIQ 305
Cdd:pfam09770 171 AAPAPAPQPAAQPASLPAPSRKMMSLEEVEAAMRAQAKKPAQQPApapaqppaAPPAQQAQQQQQFPPQIQQQQQPQQQP 250

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 357527439  306 PQALQIQTQPKLLRQAQTQTSPEhLAPQQDQVPTQAQSQEQTSEKTQDQP---------QTWPQGSVPPPEQASGPACAT 376
Cdd:pfam09770 251 QQPQQHPGQGHPVTILQRPQSPQ-PDPAQPSIQPQAQQFHQQPPPVPVQPtqilqnpnrLSAARVGYPQNPQPGVQPAPA 329

                         250       260       270
                  ....*....|....*....|....*....|.
gi 357527439  377 EPQLSSHAAEAGSDPDKALPEPVSAQSSEDR 407
Cdd:pfam09770 330 HQAHRQQGSFGRQAPIITHPQQLAQLSEEEK 360
ZnF_U1 smart00451
U1-like zinc finger; Family of C2H2-type zinc fingers, present in matrin, U1 small nuclear ...
 692-725 1.57e-03

U1-like zinc finger; Family of C2H2-type zinc fingers, present in matrin, U1 small nuclear ribonucleoprotein C and other RNA-binding proteins.


Pssm-ID: 197732 [Multi-domain]  Cd Length: 35  Bit Score: 36.85  E-value: 1.57e-03
                           10        20        30
                   ....*....|....*....|....*....|....
gi 357527439   692 GYVCQICHKFYDSNSELRlSHCKSLAHFENLQKY 725
Cdd:smart00451   3 GFYCKLCNVTFTDEISVE-AHLKGKKHKKNVKKR 35
GIY-YIG_PLEs cd10442
Catalytic GIY-YIG endonuclease domain of penelope-like elements and similar proteins; This ...
 545-612 2.65e-03

Catalytic GIY-YIG endonuclease domain of penelope-like elements and similar proteins; This model corresponds to the EN domain of PLEs that contains catalytic module of the GIY-YIG endonucleases of group I bacterial/organellar introns, as well as bacterial UvrC DNA repair proteins. It can cleave DNA with low nucleotide sequence specificity. However, the PLEs EN domain is distinct from other GIY-YIG endonucleases by the presence of a well-conserved CCHH motif (CX(2-7)CX(33-39)HX(3-5)H, X can be any residue). The role of the CCHH motif has not yet been identified. Penelope-like elements (PLEs) represent a novel class of eukaryotic retroelements, which do not belong to either long terminal repeat (LTR) retrotransposons or non-LTR retrotransposons (often called LINEs), but instead form a sister clade to telomerase reverse transcriptases (TERTs), highly specialized non-mobile reverse transcriptases (RTs) which are responsible for the addition of telomeric repeats to the ends of eukaryotic chromosomes. The single open reading frame (ORF) encoded by PLE consists of two principal domains, RT domain and endonuclease (EN) domain, jointed by a linker region of variable length. Both of these two domains are functionally active.


Pssm-ID: 198389  Cd Length: 92  Bit Score: 37.73  E-value: 2.65e-03
                         10        20        30        40        50        60        70
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 357527439 545 WCNTCQVYYVGDLIQ--HRRTQEHKVAKQSlrpfcticNRYFKTPrkFVEHVKSQGHKDKAQELKTLEKE 612
Cdd:cd10442    6 PCPKCGLVYIGETKRplRERMKEHRRAIRL--------SGTKKSA--VAKHFNEEGHSIDSDRVRILDKE 65
 
Name Accession Description Interval E-value
PHA03247 PHA03247
large tegument protein UL36; Provisional
 46-413 5.24e-10

large tegument protein UL36; Provisional


Pssm-ID: 223021 [Multi-domain]  Cd Length: 3151  Bit Score: 63.42  E-value: 5.24e-10
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 357527439   46 PPQASLSIPVSRGLPQQSSPQQLLSLQGLHSTSLLNGPMLQRALLLQQLQGLDQFAMPPATYDGASLTMPTATLGNLRAF 125
Cdd:PHA03247 2619 PDTHAPDPPPPSPSPAANEPDPHPPPTVPPPERPRDDPAPGRVSRPRRARRLGRAAQASSPPQRPRRRAARPTVGSLTSL 2698

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 357527439  126 NVTAPSLAAPSLTPPQMVTPNLQQFFPQATRQSLLGPP--------------PVGVPINPSQLNHSGRNTQKQARTPSST 191
Cdd:PHA03247 2699 ADPPPPPPTPEPAPHALVSATPLPPGPAAARQASPALPaapappavpagpatPGGPARPARPPTTAGPPAPAPPAAPAAG 2778

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 357527439  192 TPNRKTVPledREDPTEGSEEATELQMDTCEDQDSLVGPDSMLSEPQVPE-PEPFETLEPPAKRCRSSEESTEKGPTGQP 270
Cdd:PHA03247 2779 PPRRLTRP---AVASLSESRESLPSPWDPADPPAAVLAPAAALPPAASPAgPLPPPTSAQPTAPPPPPGPPPPSLPLGGS 2855

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 357527439  271 QARVQPQTQMTAPKQTQTPDRLPEPPEVQMLPRIQPQAlqiQTQPkllrQAQTQTSPEHLAPQQDQVPTQAQSQEQTSEK 350
Cdd:PHA03247 2856 VAPGGDVRRRPPSRSPAAKPAAPARPPVRRLARPAVSR---STES----FALPPDQPERPPQPQAPPPPQPQPQPPPPPQ 2928

                         330       340       350       360       370       380
                  ....*....|....*....|....*....|....*....|....*....|....*....|...
gi 357527439  351 TQDQPQTWPQGSVPPPEQAsGPACATEPQLSSHAAEAGSDPDKALPEPVSAQSSEDRSREASA 413
Cdd:PHA03247 2929 PQPPPPPPPRPQPPLAPTT-DPAGAGEPSGAVPQPWLGALVPGRVAVPRFRVPQPAPSREAPA 2990
PHA03247 PHA03247
large tegument protein UL36; Provisional
 47-419 1.78e-08

large tegument protein UL36; Provisional


Pssm-ID: 223021 [Multi-domain]  Cd Length: 3151  Bit Score: 58.41  E-value: 1.78e-08
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 357527439   47 PQASLSIPVSRGLPQQSSPQQLLSlqglhSTSLLNGPMLQRALLLQQLQGLDQFAMPPATYDGASLT---MPTATLGNLR 123
Cdd:PHA03247 2694 SLTSLADPPPPPPTPEPAPHALVS-----ATPLPPGPAAARQASPALPAAPAPPAVPAGPATPGGPArpaRPPTTAGPPA 2768

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 357527439  124 AFNVTAPSLAAPSLTPPQMVTPnLQQFFPQATRQSLLGPPPVGVPINPSQLNHSGRNTQKQARTPSS--TTPNRKTVPLE 201
Cdd:PHA03247 2769 PAPPAAPAAGPPRRLTRPAVAS-LSESRESLPSPWDPADPPAAVLAPAAALPPAASPAGPLPPPTSAqpTAPPPPPGPPP 2847

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 357527439  202 DREdPTEGSEEATelqmdtcedqdslvGPDSMLSEPQVPEPEPFETLEPPAKRCRSSEESTEKGPTGQPQARVQPQTQMT 281
Cdd:PHA03247 2848 PSL-PLGGSVAPG--------------GDVRRRPPSRSPAAKPAAPARPPVRRLARPAVSRSTESFALPPDQPERPPQPQ 2912

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 357527439  282 APKQTQTPDRLPEPPEVQMLPRIQPQAlQIQTQPKLLRQAQTQTSPE-------HLAPQQDQVPTQAQSQEQTSEKTqdq 354
Cdd:PHA03247 2913 APPPPQPQPQPPPPPQPQPPPPPPPRP-QPPLAPTTDPAGAGEPSGAvpqpwlgALVPGRVAVPRFRVPQPAPSREA--- 2988

                         330       340       350       360       370       380       390
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 357527439  355 pqtwPQGSVPPPEQASGPAcatepqLSSHAAEAGSDPDKAlPEPVS-----------AQSSEDRSREASAGGLDLG 419
Cdd:PHA03247 2989 ----PASSTPPLTGHSLSR------VSSWASSLALHEETD-PPPVSlkqtlwppddtEDSDADSLFDSDSERSDLE 3053
PHA03247 PHA03247
large tegument protein UL36; Provisional
 139-401 7.46e-07

large tegument protein UL36; Provisional


Pssm-ID: 223021 [Multi-domain]  Cd Length: 3151  Bit Score: 53.02  E-value: 7.46e-07
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 357527439  139 PPQMVTPNLQqffPQATRQSLLGPPPVGVPINPSQlnhsgrnTQKQARTPSSTTPNRKTVPLEDREDPtEGSEEATELQM 218
Cdd:PHA03247 2551 PPPPLPPAAP---PAAPDRSVPPPRPAPRPSEPAV-------TSRARRPDAPPQSARPRAPVDDRGDP-RGPAPPSPLPP 2619

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 357527439  219 DTCEDQDSLVGPDSMLSEPQVPEPEPFETLEPPAK-----RCRSSEESTEKGPTGQPQARVQPQTQMTAPKQTQTPDRLP 293
Cdd:PHA03247 2620 DTHAPDPPPPSPSPAANEPDPHPPPTVPPPERPRDdpapgRVSRPRRARRLGRAAQASSPPQRPRRRAARPTVGSLTSLA 2699

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 357527439  294 EPPEVQMLPRIQPQALQIQTQPKLLRQAQTQTSPE-HLAPQQDQVPTQAQSQEQTSEKTQDQPQTWPQGSVPPPEQASGP 372
Cdd:PHA03247 2700 DPPPPPPTPEPAPHALVSATPLPPGPAAARQASPAlPAAPAPPAVPAGPATPGGPARPARPPTTAGPPAPAPPAAPAAGP 2779

                         250       260       270
                  ....*....|....*....|....*....|
gi 357527439  373 A-CATEPQLSSHAAEAGSDPDKALPEPVSA 401
Cdd:PHA03247 2780 PrRLTRPAVASLSESRESLPSPWDPADPPA 2809
zf-C2H2_jaz pfam12171
Zinc-finger double-stranded RNA-binding; This domain family is found in archaea and eukaryotes, ...
 576-600 1.66e-05

Zinc-finger double-stranded RNA-binding; This domain family is found in archaea and eukaryotes, and is approximately 30 amino acids in length. The mammalian members of this group occur multiple times along the protein, joined by flexible linkers, and are referred to as JAZ - dsRNA-binding ZF protein - zinc-fingers. The JAZ proteins are expressed in all tissues tested and localize in the nucleus, particularly the nucleolus. JAZ preferentially binds to double-stranded (ds) RNA or RNA/DNA hybrids rather than DNA. In addition to binding double-stranded RNA, these zinc-fingers are required for nucleolar localization.


Pssm-ID: 432381 [Multi-domain]  Cd Length: 27  Bit Score: 42.16  E-value: 1.66e-05
                          10        20
                  ....*....|....*....|....*
gi 357527439  576 FCTICNRYFKTPRKFVEHVKSQGHK 600
Cdd:pfam12171   3 YCVLCDKYFKSENALQNHLKSKKHK 27
PRK10927 PRK10927
cell division protein FtsN;
240-407 1.83e-05

cell division protein FtsN;


Pssm-ID: 236797 [Multi-domain]  Cd Length: 319  Bit Score: 47.37  E-value: 1.83e-05
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 357527439 240 PEPEP----FETLEPPAKRCRSSEESTEKGPTGQPQARVQPQTQMTAPKQT---QTPDRLPEPPEVQMLPRIQPQALQIQ 312
Cdd:PRK10927  77 PKPEErwryIKELESRQPGVRAPTEPSAGGEVKTPEQLTPEQRQLLEQMQAdmrQQPTQLVEVPWNEQTPEQRQQTLQRQ 156

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 357527439 313 TQpkllRQAQTQTSPEHLAPQQDQVPTQAQSQEQTSEKTQDQPQTWPQGSVPPPEQ--ASGPACATEPQLSSHAAEAGSD 390
Cdd:PRK10927 157 RQ----AQQLAEQQRLAQQSRTTEQSWQQQTRTSQAAPVQAQPRQSKPASTQQPYQdlLQTPAHTTAQSKPQQAAPVTRA 232

                        170
                 ....*....|....*..
gi 357527439 391 PDKalPEPVSAQSSEDR 407
Cdd:PRK10927 233 ADA--PKPTAEKKDERR 247
PRK10263 PRK10263
DNA translocase FtsK; Provisional
 194-407 2.54e-04

DNA translocase FtsK; Provisional


Pssm-ID: 236669 [Multi-domain]  Cd Length: 1355  Bit Score: 44.69  E-value: 2.54e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 357527439  194 NRKTVPLEDREDPTEGSEEATE----LQMDTCEDQDSLVGPDSMLSEPQVPEPEPfETLEP-----PAKRCRSSEESTEK 264
Cdd:PRK10263  297 NRATQPEYDEYDPLLNGAPITEpvavAAAATTATQSWAAPVEPVTQTPPVASVDV-PPAQPtvawqPVPGPQTGEPVIAP 375

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 357527439  265 GPTGQPQA--RVQPQTQMTAPKQTqtpdrlPEPPEVqmlPRIQPQALQIQTQPKLLRQAQTQTSPEHLAPQQDQVPTQAQ 342
Cdd:PRK10263  376 APEGYPQQsqYAQPAVQYNEPLQQ------PVQPQQ---PYYAPAAEQPAQQPYYAPAPEQPAQQPYYAPAPEQPVAGNA 446

                         170       180       190       200       210       220
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 357527439  343 SQeqtsekTQDQPQTWPQGSVPPPEQASGPACATEPQlsSHAAEAGSDPDKALPEPVSAQSSEDR 407
Cdd:PRK10263  447 WQ------AEEQQSTFAPQSTYQTEQTYQQPAAQEPL--YQQPQPVEQQPVVEPEPVVEETKPAR 503
PRK10263 PRK10263
DNA translocase FtsK; Provisional
 229-378 5.17e-04

DNA translocase FtsK; Provisional


Pssm-ID: 236669 [Multi-domain]  Cd Length: 1355  Bit Score: 43.92  E-value: 5.17e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 357527439  229 GPDSMLSEPQV-PEPEPFETLEPPAKrcrsseestekgpTGQPQARVQPQTQMTAPKQTQTPDRLPEPPEVQMLPRIQPQ 307
Cdd:PRK10263  739 GPHEPLFTPIVePVQQPQQPVAPQQQ-------------YQQPQQPVAPQPQYQQPQQPVAPQPQYQQPQQPVAPQPQYQ 805

                          90       100       110       120       130       140       150
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 357527439  308 ALQIQTQPKLLRQAQTQTSPEHLAPQQDQVPTQAQSQEQ-----TSEKTQDQPQTWPQGSVPPPEQASGPACATEP 378
Cdd:PRK10263  806 QPQQPVAPQPQYQQPQQPVAPQPQYQQPQQPVAPQPQDTllhplLMRNGDSRPLHKPTTPLPSLDLLTPPPSEVEP 881
PAT1 pfam09770
Topoisomerase II-associated protein PAT1; Members of this family are necessary for accurate ...
 156-407 7.23e-04

Topoisomerase II-associated protein PAT1; Members of this family are necessary for accurate chromosome transmission during cell division.


Pssm-ID: 401645 [Multi-domain]  Cd Length: 846  Bit Score: 43.10  E-value: 7.23e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 357527439  156 RQSLLGPPPVGVPINPSQLNHSGRNTQKQARTPSSTTPNRKTvPLEDREDPtegsEEATELQMDTcedqdSL--VGPDSM 233
Cdd:pfam09770 101 RFNRQQPAARAAQSSAQPPASSLPQYQYASQQSQQPSKPVRT-GYEKYKEP----EPIPDLQVDA-----SLwgVAPKKA 170

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 357527439  234 LSEPQVPEPEPFETLEPPAKRCRSSEESTEKGPTGQPQARVQPQT--------QMTAPKQTQTPDRLPEPPEVQMLPRIQ 305
Cdd:pfam09770 171 AAPAPAPQPAAQPASLPAPSRKMMSLEEVEAAMRAQAKKPAQQPApapaqppaAPPAQQAQQQQQFPPQIQQQQQPQQQP 250

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 357527439  306 PQALQIQTQPKLLRQAQTQTSPEhLAPQQDQVPTQAQSQEQTSEKTQDQP---------QTWPQGSVPPPEQASGPACAT 376
Cdd:pfam09770 251 QQPQQHPGQGHPVTILQRPQSPQ-PDPAQPSIQPQAQQFHQQPPPVPVQPtqilqnpnrLSAARVGYPQNPQPGVQPAPA 329

                         250       260       270
                  ....*....|....*....|....*....|.
gi 357527439  377 EPQLSSHAAEAGSDPDKALPEPVSAQSSEDR 407
Cdd:pfam09770 330 HQAHRQQGSFGRQAPIITHPQQLAQLSEEEK 360
PHA03247 PHA03247
large tegument protein UL36; Provisional
 130-391 1.45e-03

large tegument protein UL36; Provisional


Pssm-ID: 223021 [Multi-domain]  Cd Length: 3151  Bit Score: 42.23  E-value: 1.45e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 357527439  130 PSLAAPSLTPPQMVTPNLQQFFPQATRQSLLGPPPVGVPINPSQLNHSG-------RNTQKQARTPSSTTPNRKTVPLED 202
Cdd:PHA03247 2609 RGPAPPSPLPPDTHAPDPPPPSPSPAANEPDPHPPPTVPPPERPRDDPApgrvsrpRRARRLGRAAQASSPPQRPRRRAA 2688

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 357527439  203 RedPTegseeatelqmdtcedqdslVGPDSMLSEPQVPEPEPfETLEPPAKRCRSSEESTEKGPTGQPQARVQPQTQM-- 280
Cdd:PHA03247 2689 R--PT--------------------VGSLTSLADPPPPPPTP-EPAPHALVSATPLPPGPAAARQASPALPAAPAPPAvp 2745

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 357527439  281 TAPKQTQTPDRLPEPPEVQMLPRIQPQALQIQT-QPKLLRQAQTQTSPEHLAPQQDQVPTQAQSQEQTSEKTQDQPQTwP 359
Cdd:PHA03247 2746 AGPATPGGPARPARPPTTAGPPAPAPPAAPAAGpPRRLTRPAVASLSESRESLPSPWDPADPPAAVLAPAAALPPAAS-P 2824

                         250       260       270
                  ....*....|....*....|....*....|....
gi 357527439  360 QGSVPPPEQA--SGPACATEPQLSSHAAEAGSDP 391
Cdd:PHA03247 2825 AGPLPPPTSAqpTAPPPPPGPPPPSLPLGGSVAP 2858
ZnF_U1 smart00451
U1-like zinc finger; Family of C2H2-type zinc fingers, present in matrin, U1 small nuclear ...
 692-725 1.57e-03

U1-like zinc finger; Family of C2H2-type zinc fingers, present in matrin, U1 small nuclear ribonucleoprotein C and other RNA-binding proteins.


Pssm-ID: 197732 [Multi-domain]  Cd Length: 35  Bit Score: 36.85  E-value: 1.57e-03
                           10        20        30
                   ....*....|....*....|....*....|....
gi 357527439   692 GYVCQICHKFYDSNSELRlSHCKSLAHFENLQKY 725
Cdd:smart00451   3 GFYCKLCNVTFTDEISVE-AHLKGKKHKKNVKKR 35
GIY-YIG_PLEs cd10442
Catalytic GIY-YIG endonuclease domain of penelope-like elements and similar proteins; This ...
 545-612 2.65e-03

Catalytic GIY-YIG endonuclease domain of penelope-like elements and similar proteins; This model corresponds to the EN domain of PLEs that contains catalytic module of the GIY-YIG endonucleases of group I bacterial/organellar introns, as well as bacterial UvrC DNA repair proteins. It can cleave DNA with low nucleotide sequence specificity. However, the PLEs EN domain is distinct from other GIY-YIG endonucleases by the presence of a well-conserved CCHH motif (CX(2-7)CX(33-39)HX(3-5)H, X can be any residue). The role of the CCHH motif has not yet been identified. Penelope-like elements (PLEs) represent a novel class of eukaryotic retroelements, which do not belong to either long terminal repeat (LTR) retrotransposons or non-LTR retrotransposons (often called LINEs), but instead form a sister clade to telomerase reverse transcriptases (TERTs), highly specialized non-mobile reverse transcriptases (RTs) which are responsible for the addition of telomeric repeats to the ends of eukaryotic chromosomes. The single open reading frame (ORF) encoded by PLE consists of two principal domains, RT domain and endonuclease (EN) domain, jointed by a linker region of variable length. Both of these two domains are functionally active.


Pssm-ID: 198389  Cd Length: 92  Bit Score: 37.73  E-value: 2.65e-03
                         10        20        30        40        50        60        70
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 357527439 545 WCNTCQVYYVGDLIQ--HRRTQEHKVAKQSlrpfcticNRYFKTPrkFVEHVKSQGHKDKAQELKTLEKE 612
Cdd:cd10442    6 PCPKCGLVYIGETKRplRERMKEHRRAIRL--------SGTKKSA--VAKHFNEEGHSIDSDRVRILDKE 65
PRK10263 PRK10263
DNA translocase FtsK; Provisional
 296-407 2.82e-03

DNA translocase FtsK; Provisional


Pssm-ID: 236669 [Multi-domain]  Cd Length: 1355  Bit Score: 41.22  E-value: 2.82e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 357527439  296 PEVQMLPRIQPQALQIQTQPKLLRQAQTQTSPEHLAPQQDQVPTQAQSQEQTSEKTQDQPQTwPQGSVPPPEQASGPaca 375
Cdd:PRK10263  751 PVQQPQQPVAPQQQYQQPQQPVAPQPQYQQPQQPVAPQPQYQQPQQPVAPQPQYQQPQQPVA-PQPQYQQPQQPVAP--- 826

                          90       100       110
                  ....*....|....*....|....*....|..
gi 357527439  376 tEPQLSSHAAEAGSDPDKALPEPVSAQSSEDR 407
Cdd:PRK10263  827 -QPQYQQPQQPVAPQPQDTLLHPLLMRNGDSR 857
PRK07764 PRK07764
DNA polymerase III subunits gamma and tau; Validated
 229-417 3.33e-03

DNA polymerase III subunits gamma and tau; Validated


Pssm-ID: 236090 [Multi-domain]  Cd Length: 824  Bit Score: 41.12  E-value: 3.33e-03
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 357527439 229 GPDSMLSEPQVPEPEPFETLEPPAKRCR------SSEESTEKGPTGQPQARVQPQTQMTAPKQT---QTPDRLPEPPEVQ 299
Cdd:PRK07764 602 APASSGPPEEAARPAAPAAPAAPAAPAPagaaaaPAEASAAPAPGVAAPEHHPKHVAVPDASDGgdgWPAKAGGAAPAAP 681

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 357527439 300 MLPRIQPQALQIQTQPKllRQAQTQTSPEHLAPQQDQVPTQAQSQEQTsektQDQPQTWPQGSVPPPEQASGPACATEPQ 379
Cdd:PRK07764 682 PPAPAPAAPAAPAGAAP--AQPAPAPAATPPAGQADDPAAQPPQAAQG----ASAPSPAADDPVPLPPEPDDPPDPAGAP 755

                        170       180       190
                 ....*....|....*....|....*....|....*....
gi 357527439 380 LSSHAAEAGSDPDKALPEP-VSAQSSEDRSREASAGGLD 417
Cdd:PRK07764 756 AQPPPPPAPAPAAAPAAAPpPSPPSEEEEMAEDDAPSMD 794
PRK12757 PRK12757
cell division protein FtsN; Provisional
 266-373 6.10e-03

cell division protein FtsN; Provisional


Pssm-ID: 237191 [Multi-domain]  Cd Length: 256  Bit Score: 39.26  E-value: 6.10e-03
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 357527439 266 PTGQPQARVQPQ---------TQMTAPKQtQTPDRLPEPPEVQMLPRIQPQALQIQTQPKLLRQAQTQTSPehlAPQQDQ 336
Cdd:PRK12757  68 PSAGGEVNSPTQltdeqrqllEQMQADMR-QQPTQLSEVPYNEQTPQVPRSTVQIQQQAQQQQPPATTAQP---QPVTPP 143

                         90       100       110
                 ....*....|....*....|....*....|....*..
gi 357527439 337 VPTQAQSQEQTSEKTQDQPQTWPQGSVPPPEQASGPA 373
Cdd:PRK12757 144 RQTTAPVQPQTPAPVRTQPAAPVTQAVEAPKVEAEKE 180
PRK10927 PRK10927
cell division protein FtsN;
249-369 6.71e-03

cell division protein FtsN;


Pssm-ID: 236797 [Multi-domain]  Cd Length: 319  Bit Score: 39.28  E-value: 6.71e-03
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 357527439 249 EPPAKRCRSSEESTEKGPTGQPQARVQPQTQMTAPKQTQTpdRLPEPPEVQMLPRIQPQALQIQTQPKLLrQAQTQTSPE 328
Cdd:PRK10927 144 QTPEQRQQTLQRQRQAQQLAEQQRLAQQSRTTEQSWQQQT--RTSQAAPVQAQPRQSKPASTQQPYQDLL-QTPAHTTAQ 220

                         90       100       110       120
                 ....*....|....*....|....*....|....*....|.
gi 357527439 329 HLAPQQDQVPTQAQSQEQTSEKTQDQPQTWPQGSVPPPEQA 369
Cdd:PRK10927 221 SKPQQAAPVTRAADAPKPTAEKKDERRWMVQCGSFRGAEQA 261
PRK07764 PRK07764
DNA polymerase III subunits gamma and tau; Validated
 260-395 8.16e-03

DNA polymerase III subunits gamma and tau; Validated


Pssm-ID: 236090 [Multi-domain]  Cd Length: 824  Bit Score: 39.58  E-value: 8.16e-03
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 357527439 260 ESTEKGPTGQPQARVQPQTQMTAPKQTQTPDRLPEPPEVQMLPRIQPQAlqiQTQPKLLRQAQTQTSPEHLAPQQDQVPT 339
Cdd:PRK07764 379 ERLERRLGVAGGAGAPAAAAPSAAAAAPAAAPAPAAAAPAAAAAPAPAA---APQPAPAPAPAPAPPSPAGNAPAGGAPS 455

                         90       100       110       120       130
                 ....*....|....*....|....*....|....*....|....*....|....*..
gi 357527439 340 QAQSQEQTSEKTQDQPQTWPQGSVPPPEQASGPACATEPQLSSH-AAEAGSDPDKAL 395
Cdd:PRK07764 456 PPPAAAPSAQPAPAPAAAPEPTAAPAPAPPAAPAPAAAPAAPAApAAPAGADDAATL 512
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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