NCBI Home Page NCBI Site Search page NCBI Guide that lists and describes the NCBI resources
Conserved domains on  [gi|525314175|ref|NP_001265640|]
View 

neuritin isoform 2 [Homo sapiens]

Protein Classification

NRN1 domain-containing protein( domain architecture ID 10633353)

NRN1 domain-containing protein

Graphical summary

 Zoom to residue level

show extra options »

Show site features     Horizontal zoom: ×

List of domain hits

 Name Accession Description Interval E-value
NRN1 pfam15056
Neuritin protein family; The domain family Neuritin1 (NRN1) is a GPI-anchored protein ...
 57-143 2.70e-52

Neuritin protein family; The domain family Neuritin1 (NRN1) is a GPI-anchored protein expressed in post-mitotic-differentiating neurons in the developing nervous system. NRN1 is a glutamate and neurotrophin receptor target encoding a neuronal protein that functions extracellularly to modulate neurite outgrowth (OMIM:607409). This family of proteins is found in eukaryotes. Proteins in this family are typically between and 158 amino acids in length.


:

Pssm-ID: 434424  Cd Length: 89  Bit Score: 161.40  E-value: 2.70e-52
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 525314175   57 CDAVFKGFSDCLLKLGDSMANYPQGLDDK--TNIKTVCTYWEDFHSCTVTALTDCQEGAKDMWDKLRKESKNLNIQGSLF 134
Cdd:pfam15056   1 CDAIYKGFSDCLLKLGDSMANYPQELDDEetQNLDTICKYWDDFHTCALTALSDCQEEAADVWESLRQESKKLQFQGSLF 80


                  ....*....
gi 525314175  135 ELCGSGNGA 143
Cdd:pfam15056  81 DLCSSRNSA 89
 
Name Accession Description Interval E-value
NRN1 pfam15056
Neuritin protein family; The domain family Neuritin1 (NRN1) is a GPI-anchored protein ...
 57-143 2.70e-52

Neuritin protein family; The domain family Neuritin1 (NRN1) is a GPI-anchored protein expressed in post-mitotic-differentiating neurons in the developing nervous system. NRN1 is a glutamate and neurotrophin receptor target encoding a neuronal protein that functions extracellularly to modulate neurite outgrowth (OMIM:607409). This family of proteins is found in eukaryotes. Proteins in this family are typically between and 158 amino acids in length.


Pssm-ID: 434424  Cd Length: 89  Bit Score: 161.40  E-value: 2.70e-52
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 525314175   57 CDAVFKGFSDCLLKLGDSMANYPQGLDDK--TNIKTVCTYWEDFHSCTVTALTDCQEGAKDMWDKLRKESKNLNIQGSLF 134
Cdd:pfam15056   1 CDAIYKGFSDCLLKLGDSMANYPQELDDEetQNLDTICKYWDDFHTCALTALSDCQEEAADVWESLRQESKKLQFQGSLF 80


                  ....*....
gi 525314175  135 ELCGSGNGA 143
Cdd:pfam15056  81 DLCSSRNSA 89
 
Name Accession Description Interval E-value
NRN1 pfam15056
Neuritin protein family; The domain family Neuritin1 (NRN1) is a GPI-anchored protein ...
 57-143 2.70e-52

Neuritin protein family; The domain family Neuritin1 (NRN1) is a GPI-anchored protein expressed in post-mitotic-differentiating neurons in the developing nervous system. NRN1 is a glutamate and neurotrophin receptor target encoding a neuronal protein that functions extracellularly to modulate neurite outgrowth (OMIM:607409). This family of proteins is found in eukaryotes. Proteins in this family are typically between and 158 amino acids in length.


Pssm-ID: 434424  Cd Length: 89  Bit Score: 161.40  E-value: 2.70e-52
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 525314175   57 CDAVFKGFSDCLLKLGDSMANYPQGLDDK--TNIKTVCTYWEDFHSCTVTALTDCQEGAKDMWDKLRKESKNLNIQGSLF 134
Cdd:pfam15056   1 CDAIYKGFSDCLLKLGDSMANYPQELDDEetQNLDTICKYWDDFHTCALTALSDCQEEAADVWESLRQESKKLQFQGSLF 80


                  ....*....
gi 525314175  135 ELCGSGNGA 143
Cdd:pfam15056  81 DLCSSRNSA 89
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
Help | Disclaimer | Write to the Help Desk
NCBI | NLM | NIH