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Conserved domains on  [gi|114205399|ref|NP_001288|]
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cyclic nucleotide-gated channel beta-1 isoform a [Homo sapiens]

Protein Classification

cyclic nucleotide-gated ion channel( domain architecture ID 13328258)

cyclic nucleotide-gated ion channel is a nonselective channel that is opened by the direct binding of cyclic nucleotides, cAMP and cGMP

CATH:  2.60.120.10
Gene Ontology:  GO:0016020|GO:0030551|GO:0005216|GO:0006811|GO:0022832
PubMed:  12087135|17601606
SCOP:  4000272
TCDB:  1.A.1

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
CAP_ED cd00038
effector domain of the CAP family of transcription factors; members include CAP (or cAMP ...
 962-1071 3.47e-23

effector domain of the CAP family of transcription factors; members include CAP (or cAMP receptor protein (CRP)), which binds cAMP, FNR (fumarate and nitrate reduction), which uses an iron-sulfur cluster to sense oxygen) and CooA, a heme containing CO sensor. In all cases binding of the effector leads to conformational changes and the ability to activate transcription. Cyclic nucleotide-binding domain similar to CAP are also present in cAMP- and cGMP-dependent protein kinases (cAPK and cGPK) and vertebrate cyclic nucleotide-gated ion-channels. Cyclic nucleotide-monophosphate binding domain; proteins that bind cyclic nucleotides (cAMP or cGMP) share a structural domain of about 120 residues; the best studied is the prokaryotic catabolite gene activator, CAP, where such a domain is known to be composed of three alpha-helices and a distinctive eight-stranded, antiparallel beta-barrel structure; three conserved glycine residues are thought to be essential for maintenance of the structural integrity of the beta-barrel; CooA is a homodimeric transcription factor that belongs to CAP family; cAMP- and cGMP-dependent protein kinases (cAPK and cGPK) contain two tandem copies of the cyclic nucleotide-binding domain; cAPK's are composed of two different subunits, a catalytic chain and a regulatory chain, which contains both copies of the domain; cGPK's are single chain enzymes that include the two copies of the domain in their N-terminal section; also found in vertebrate cyclic nucleotide-gated ion-channels


:

Pssm-ID: 237999 [Multi-domain]  Cd Length: 115  Bit Score: 95.86  E-value: 3.47e-23
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 114205399  962 LFQGCDRQMIFDMLKRLRSVVYLPNDYVCKKGEIGREMYIIQAGQVQVL-GGPDGKSVLV-TLKAGSVFGEISLLavgGG 1039
Cdd:cd00038     1 LFSGLDDEELEELADALEERRFPAGEVIIRQGDPADSLYIVLSGSVEVYkLDEDGREQIVgFLGPGDLFGELALL---GN 77

                          90       100       110
                  ....*....|....*....|....*....|..
gi 114205399 1040 NRRTANVVAHGFTNLFILDKKDLNEILVHYPE 1071
Cdd:cd00038    78 GPRSATVRALTDSELLVLPRSDFRRLLQEYPE 109
PLN03192 super family cl33658
Voltage-dependent potassium channel; Provisional
 648-1034 3.52e-19

Voltage-dependent potassium channel; Provisional


The actual alignment was detected with superfamily member PLN03192:

Pssm-ID: 215625 [Multi-domain]  Cd Length: 823  Bit Score: 93.78  E-value: 3.52e-19
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 114205399  648 IDPLTNlMYVLWLFFVVMAWNWNCWLIPVRWAFPYQTPDNihHWLLMDYLCDLIYFLDI--TVF----QTRLQFvrggdI 721
Cdd:PLN03192   54 ISPMDS-RYRWWETLMVVLVAYSAWVYPFEVAFLNASPKR--GLEIADNVVDLFFAVDIvlTFFvayiDPRTQL-----L 125

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 114205399  722 ITDKKDMRNNYLkSRRFKMDLLSLLP-LDFLYLKVG---------VNPLLRLPRCLKYMAFFefnSRLESILSKAYVY-R 790
Cdd:PLN03192  126 VRDRKKIAVRYL-STWFLMDVASTIPfQALAYLITGtvklnlsysLLGLLRFWRLRRVKQLF---TRLEKDIRFSYFWiR 201

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 114205399  791 VIRTTAYLLYSLHLNSCLYYW-ASAYQGLGSThWVYDGVGN--------SYIRCYYFAVKTLITIG-----GLPDPKTLF 856
Cdd:PLN03192  202 CARLLSVTLFLVHCAGCLYYLiADRYPHQGKT-WIGAVIPNfretslwiRYISAIYWSITTMTTVGygdlhAVNTIEMIF 280

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 114205399  857 EIVFQLLNYftGVFAFsvMIGQMRDVVGAATAGQTYYRSCMDSTVKYMNFYKIPKSVQNRVKTWYEYTWHSQGmLDESEL 936
Cdd:PLN03192  281 IIFYMLFNL--GLTAY--LIGNMTNLVVEGTRRTMEFRNSIEAASNFVGRNRLPPRLKDQILAYMCLRFKAES-LNQQQL 355

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 114205399  937 MVQLPDKMRLDLAIDVNYNIVSKVALFQGCDRQMIFDMLKRLRSVVYLPNDYVCKKGEIGREMYIIQAGQVQV-LGGPDG 1015
Cdd:PLN03192  356 IDQLPKSICKSICQHLFLPVVEKVYLFKGVSREILLLLVTKMKAEYIPPREDVIMQNEAPDDVYIVVSGEVEIiDSEGEK 435

                         410
                  ....*....|....*....
gi 114205399 1016 KSVLVTLKAGSVFGEISLL 1034
Cdd:PLN03192  436 ERVVGTLGCGDIFGEVGAL 454
PRK10263 super family cl35903
DNA translocase FtsK; Provisional
 167-311 4.75e-05

DNA translocase FtsK; Provisional


The actual alignment was detected with superfamily member PRK10263:

Pssm-ID: 236669 [Multi-domain]  Cd Length: 1355  Bit Score: 47.77  E-value: 4.75e-05
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 114205399  167 ERVLPQPP-KSSEV--------WRDEPAVATGAAS-DPAP---PGRPQEMGPKLQARETPSLPTPIPLQPKEEPKEAPAP 233
Cdd:PRK10263  338 EPVTQTPPvASVDVppaqptvaWQPVPGPQTGEPViAPAPegyPQQSQYAQPAVQYNEPLQQPVQPQQPYYAPAAEQPAQ 417

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 114205399  234 EPQPGSQAQT-----SSLPPTRDPARLVAWVLHRLEMAL-PQPVLHGKIGEQEPDSPGICDVQTISILPGGQVEPDLVLE 307
Cdd:PRK10263  418 QPYYAPAPEQpaqqpYYAPAPEQPVAGNAWQAEEQQSTFaPQSTYQTEQTYQQPAAQEPLYQQPQPVEQQPVVEPEPVVE 497


                  ....
gi 114205399  308 EVEP 311
Cdd:PRK10263  498 ETKP 501
 
Name Accession Description Interval E-value
CAP_ED cd00038
effector domain of the CAP family of transcription factors; members include CAP (or cAMP ...
 962-1071 3.47e-23

effector domain of the CAP family of transcription factors; members include CAP (or cAMP receptor protein (CRP)), which binds cAMP, FNR (fumarate and nitrate reduction), which uses an iron-sulfur cluster to sense oxygen) and CooA, a heme containing CO sensor. In all cases binding of the effector leads to conformational changes and the ability to activate transcription. Cyclic nucleotide-binding domain similar to CAP are also present in cAMP- and cGMP-dependent protein kinases (cAPK and cGPK) and vertebrate cyclic nucleotide-gated ion-channels. Cyclic nucleotide-monophosphate binding domain; proteins that bind cyclic nucleotides (cAMP or cGMP) share a structural domain of about 120 residues; the best studied is the prokaryotic catabolite gene activator, CAP, where such a domain is known to be composed of three alpha-helices and a distinctive eight-stranded, antiparallel beta-barrel structure; three conserved glycine residues are thought to be essential for maintenance of the structural integrity of the beta-barrel; CooA is a homodimeric transcription factor that belongs to CAP family; cAMP- and cGMP-dependent protein kinases (cAPK and cGPK) contain two tandem copies of the cyclic nucleotide-binding domain; cAPK's are composed of two different subunits, a catalytic chain and a regulatory chain, which contains both copies of the domain; cGPK's are single chain enzymes that include the two copies of the domain in their N-terminal section; also found in vertebrate cyclic nucleotide-gated ion-channels


Pssm-ID: 237999 [Multi-domain]  Cd Length: 115  Bit Score: 95.86  E-value: 3.47e-23
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 114205399  962 LFQGCDRQMIFDMLKRLRSVVYLPNDYVCKKGEIGREMYIIQAGQVQVL-GGPDGKSVLV-TLKAGSVFGEISLLavgGG 1039
Cdd:cd00038     1 LFSGLDDEELEELADALEERRFPAGEVIIRQGDPADSLYIVLSGSVEVYkLDEDGREQIVgFLGPGDLFGELALL---GN 77

                          90       100       110
                  ....*....|....*....|....*....|..
gi 114205399 1040 NRRTANVVAHGFTNLFILDKKDLNEILVHYPE 1071
Cdd:cd00038    78 GPRSATVRALTDSELLVLPRSDFRRLLQEYPE 109
cNMP smart00100
Cyclic nucleotide-monophosphate binding domain; Catabolite gene activator protein (CAP) is a ...
 962-1079 1.17e-20

Cyclic nucleotide-monophosphate binding domain; Catabolite gene activator protein (CAP) is a prokaryotic homologue of eukaryotic cNMP-binding domains, present in ion channels, and cNMP-dependent kinases.


Pssm-ID: 197516 [Multi-domain]  Cd Length: 120  Bit Score: 88.61  E-value: 1.17e-20
                            10        20        30        40        50        60        70        80
                    ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 114205399    962 LFQGCDRQMIFDMLKRLRSVVYLPNDYVCKKGEIGREMYIIQAGQVQV--LGGPDGKSVLVTLKAGSVFGEISLLAvGGG 1039
Cdd:smart00100    1 LFKNLDAEELRELADALEPVRYPAGEVIIRQGDVGDSFYIIVSGEVEVykVLEDGEEQIVGTLGPGDFFGELALLT-NSR 79

                            90       100       110       120
                    ....*....|....*....|....*....|....*....|
gi 114205399   1040 NRRTANVVAHGFTNLFILDKKDLNEILVHYPESQKLLRKK 1079
Cdd:smart00100   80 RAASAAAVALELATLLRIDFRDFLQLLPELPQLLLELLLE 119
PLN03192 PLN03192
Voltage-dependent potassium channel; Provisional
 648-1034 3.52e-19

Voltage-dependent potassium channel; Provisional


Pssm-ID: 215625 [Multi-domain]  Cd Length: 823  Bit Score: 93.78  E-value: 3.52e-19
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 114205399  648 IDPLTNlMYVLWLFFVVMAWNWNCWLIPVRWAFPYQTPDNihHWLLMDYLCDLIYFLDI--TVF----QTRLQFvrggdI 721
Cdd:PLN03192   54 ISPMDS-RYRWWETLMVVLVAYSAWVYPFEVAFLNASPKR--GLEIADNVVDLFFAVDIvlTFFvayiDPRTQL-----L 125

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 114205399  722 ITDKKDMRNNYLkSRRFKMDLLSLLP-LDFLYLKVG---------VNPLLRLPRCLKYMAFFefnSRLESILSKAYVY-R 790
Cdd:PLN03192  126 VRDRKKIAVRYL-STWFLMDVASTIPfQALAYLITGtvklnlsysLLGLLRFWRLRRVKQLF---TRLEKDIRFSYFWiR 201

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 114205399  791 VIRTTAYLLYSLHLNSCLYYW-ASAYQGLGSThWVYDGVGN--------SYIRCYYFAVKTLITIG-----GLPDPKTLF 856
Cdd:PLN03192  202 CARLLSVTLFLVHCAGCLYYLiADRYPHQGKT-WIGAVIPNfretslwiRYISAIYWSITTMTTVGygdlhAVNTIEMIF 280

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 114205399  857 EIVFQLLNYftGVFAFsvMIGQMRDVVGAATAGQTYYRSCMDSTVKYMNFYKIPKSVQNRVKTWYEYTWHSQGmLDESEL 936
Cdd:PLN03192  281 IIFYMLFNL--GLTAY--LIGNMTNLVVEGTRRTMEFRNSIEAASNFVGRNRLPPRLKDQILAYMCLRFKAES-LNQQQL 355

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 114205399  937 MVQLPDKMRLDLAIDVNYNIVSKVALFQGCDRQMIFDMLKRLRSVVYLPNDYVCKKGEIGREMYIIQAGQVQV-LGGPDG 1015
Cdd:PLN03192  356 IDQLPKSICKSICQHLFLPVVEKVYLFKGVSREILLLLVTKMKAEYIPPREDVIMQNEAPDDVYIVVSGEVEIiDSEGEK 435

                         410
                  ....*....|....*....
gi 114205399 1016 KSVLVTLKAGSVFGEISLL 1034
Cdd:PLN03192  436 ERVVGTLGCGDIFGEVGAL 454
Ion_trans pfam00520
Ion transport protein; This family contains sodium, potassium and calcium ion channels. This ...
 658-881 1.56e-16

Ion transport protein; This family contains sodium, potassium and calcium ion channels. This family is 6 transmembrane helices in which the last two helices flank a loop which determines ion selectivity. In some sub-families (e.g. Na channels) the domain is repeated four times, whereas in others (e.g. K channels) the protein forms as a tetramer in the membrane.


Pssm-ID: 459842 [Multi-domain]  Cd Length: 238  Bit Score: 80.39  E-value: 1.56e-16
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 114205399   658 LWLFFVVMAWNWNCWLIPVRWAFPYQTPDNIHhWLLMDYLCDLIYFLDITvfqtrLQFVRGGDIItdkkdmrnNYLKSRR 737
Cdd:pfam00520    3 YFELFILLLILLNTIFLALETYFQPEEPLTTV-LEILDYVFTGIFTLEML-----LKIIAAGFKK--------RYFRSPW 68

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 114205399   738 FKMDLLSLLPLDFLYLKVGVNP--LLRLPRCLKYMAFFEFNSRLESIlsKAYVY---RVIRTTAYLLYSLHLNSCLYYWA 812
Cdd:pfam00520   69 NILDFVVVLPSLISLVLSSVGSlsGLRVLRLLRLLRLLRLIRRLEGL--RTLVNsliRSLKSLGNLLLLLLLFLFIFAII 146

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 114205399   813 sAYQGLGST--HWVYDGVGN----SYIRCYYFAVKTLITIgGLPD--PKTLFE-------IVFQLLNYFTGVFAFSVMIG 877
Cdd:pfam00520  147 -GYQLFGGKlkTWENPDNGRtnfdNFPNAFLWLFQTMTTE-GWGDimYDTIDGkgefwayIYFVSFIILGGFLLLNLFIA 224


                   ....
gi 114205399   878 QMRD 881
Cdd:pfam00520  225 VIID 228
cNMP_binding pfam00027
Cyclic nucleotide-binding domain; This domain sensor domain can bind cAMP, cGMP, c-di-GMP, ...
 981-1069 1.42e-15

Cyclic nucleotide-binding domain; This domain sensor domain can bind cAMP, cGMP, c-di-GMP, oxygen and 2-oxoglutarate (Matilla et. al., FEMS Microbiology Reviews, fuab043, 45, 2021, 1. https://doi.org/10.1093/femsre/fuab043).


Pssm-ID: 459637 [Multi-domain]  Cd Length: 89  Bit Score: 73.03  E-value: 1.42e-15
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 114205399   981 VVYLPNDYVCKKGEIGREMYIIQAGQVQVLG-GPDGKSVLV-TLKAGSVFGEISLLavgGGNRRTANVVAHGFTNLFILD 1058
Cdd:pfam00027    2 RSYKAGEVIFREGDPADSLYIVLSGKVKVYRtLEDGREQILaVLGPGDFFGELALL---GGEPRSATVVALTDSELLVIP 78

                           90
                   ....*....|.
gi 114205399  1059 KKDLNEILVHY 1069
Cdd:pfam00027   79 REDFLELLERD 89
Crp COG0664
cAMP-binding domain of CRP or a regulatory subunit of cAMP-dependent protein kinases [Signal ...
 963-1089 4.84e-14

cAMP-binding domain of CRP or a regulatory subunit of cAMP-dependent protein kinases [Signal transduction mechanisms];


Pssm-ID: 440428 [Multi-domain]  Cd Length: 207  Bit Score: 72.33  E-value: 4.84e-14
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 114205399  963 FQGCDRQMIFDMLKRLRSVVYLPNDYVCKKGEIGREMYIIQAGQVQVLG-GPDGKSVLV-TLKAGSVFGEISLLavgGGN 1040
Cdd:COG0664     1 FAGLSDEELEALLAHLELRTLKKGEVLFREGDPADHLYFVLSGLVKLYRiSEDGREQILgFLGPGDFFGELSLL---GGE 77

                          90       100       110       120       130
                  ....*....|....*....|....*....|....*....|....*....|
gi 114205399 1041 RRTANVVAHGFTNLFILDKKDLNEILVHYPE-SQKLLRKKARRMLRSNNK 1089
Cdd:COG0664    78 PSPATAEALEDSELLRIPREDLEELLERNPElARALLRLLARRLRQLQER 127
PRK10263 PRK10263
DNA translocase FtsK; Provisional
 167-311 4.75e-05

DNA translocase FtsK; Provisional


Pssm-ID: 236669 [Multi-domain]  Cd Length: 1355  Bit Score: 47.77  E-value: 4.75e-05
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 114205399  167 ERVLPQPP-KSSEV--------WRDEPAVATGAAS-DPAP---PGRPQEMGPKLQARETPSLPTPIPLQPKEEPKEAPAP 233
Cdd:PRK10263  338 EPVTQTPPvASVDVppaqptvaWQPVPGPQTGEPViAPAPegyPQQSQYAQPAVQYNEPLQQPVQPQQPYYAPAAEQPAQ 417

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 114205399  234 EPQPGSQAQT-----SSLPPTRDPARLVAWVLHRLEMAL-PQPVLHGKIGEQEPDSPGICDVQTISILPGGQVEPDLVLE 307
Cdd:PRK10263  418 QPYYAPAPEQpaqqpYYAPAPEQPVAGNAWQAEEQQSTFaPQSTYQTEQTYQQPAAQEPLYQQPQPVEQQPVVEPEPVVE 497


                  ....
gi 114205399  308 EVEP 311
Cdd:PRK10263  498 ETKP 501
PLN02868 PLN02868
acyl-CoA thioesterase family protein
 975-1048 1.84e-03

acyl-CoA thioesterase family protein


Pssm-ID: 178459 [Multi-domain]  Cd Length: 413  Bit Score: 42.40  E-value: 1.84e-03
                          10        20        30        40        50        60        70
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 114205399  975 LKRLRSVV----YLPNDYVCKKGEIGREMYIIQAGQVQVLG-GPDGKSVLVTLKAGSVFGEISLlavggGNRRTANVVA 1048
Cdd:PLN02868   24 LKKIAEVVvpkrYGKGEYVVREGEPGDGLYFIWKGEAEVSGpAEEESRPEFLLKRYDYFGYGLS-----GSVHSADVVA 97
COG5373 COG5373
Uncharacterized membrane protein [Function unknown];
156-258 3.47e-03

Uncharacterized membrane protein [Function unknown];


Pssm-ID: 444140 [Multi-domain]  Cd Length: 854  Bit Score: 41.91  E-value: 3.47e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 114205399  156 LRLLLWLEQNLERVlpqppkSSEVWRDEPAVATGAASDPAPPGRPQEMGPKLQARETPSLPTPIPLQPKEEPKEAPAPEP 235
Cdd:COG5373    13 LALLVGLLGRVARL------RRRVEELEAELAEAAEAASAPAEPEPEAAAAATAAAPEAAPAPVPEAPAAPPAAAEAPAP 86

                          90       100
                  ....*....|....*....|...
gi 114205399  236 QPGSQAQTSslPPTRDPARLVAW 258
Cdd:COG5373    87 AAAAPPAEA--EPAAAPAAASSF 107
 
Name Accession Description Interval E-value
CAP_ED cd00038
effector domain of the CAP family of transcription factors; members include CAP (or cAMP ...
 962-1071 3.47e-23

effector domain of the CAP family of transcription factors; members include CAP (or cAMP receptor protein (CRP)), which binds cAMP, FNR (fumarate and nitrate reduction), which uses an iron-sulfur cluster to sense oxygen) and CooA, a heme containing CO sensor. In all cases binding of the effector leads to conformational changes and the ability to activate transcription. Cyclic nucleotide-binding domain similar to CAP are also present in cAMP- and cGMP-dependent protein kinases (cAPK and cGPK) and vertebrate cyclic nucleotide-gated ion-channels. Cyclic nucleotide-monophosphate binding domain; proteins that bind cyclic nucleotides (cAMP or cGMP) share a structural domain of about 120 residues; the best studied is the prokaryotic catabolite gene activator, CAP, where such a domain is known to be composed of three alpha-helices and a distinctive eight-stranded, antiparallel beta-barrel structure; three conserved glycine residues are thought to be essential for maintenance of the structural integrity of the beta-barrel; CooA is a homodimeric transcription factor that belongs to CAP family; cAMP- and cGMP-dependent protein kinases (cAPK and cGPK) contain two tandem copies of the cyclic nucleotide-binding domain; cAPK's are composed of two different subunits, a catalytic chain and a regulatory chain, which contains both copies of the domain; cGPK's are single chain enzymes that include the two copies of the domain in their N-terminal section; also found in vertebrate cyclic nucleotide-gated ion-channels


Pssm-ID: 237999 [Multi-domain]  Cd Length: 115  Bit Score: 95.86  E-value: 3.47e-23
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 114205399  962 LFQGCDRQMIFDMLKRLRSVVYLPNDYVCKKGEIGREMYIIQAGQVQVL-GGPDGKSVLV-TLKAGSVFGEISLLavgGG 1039
Cdd:cd00038     1 LFSGLDDEELEELADALEERRFPAGEVIIRQGDPADSLYIVLSGSVEVYkLDEDGREQIVgFLGPGDLFGELALL---GN 77

                          90       100       110
                  ....*....|....*....|....*....|..
gi 114205399 1040 NRRTANVVAHGFTNLFILDKKDLNEILVHYPE 1071
Cdd:cd00038    78 GPRSATVRALTDSELLVLPRSDFRRLLQEYPE 109
cNMP smart00100
Cyclic nucleotide-monophosphate binding domain; Catabolite gene activator protein (CAP) is a ...
 962-1079 1.17e-20

Cyclic nucleotide-monophosphate binding domain; Catabolite gene activator protein (CAP) is a prokaryotic homologue of eukaryotic cNMP-binding domains, present in ion channels, and cNMP-dependent kinases.


Pssm-ID: 197516 [Multi-domain]  Cd Length: 120  Bit Score: 88.61  E-value: 1.17e-20
                            10        20        30        40        50        60        70        80
                    ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 114205399    962 LFQGCDRQMIFDMLKRLRSVVYLPNDYVCKKGEIGREMYIIQAGQVQV--LGGPDGKSVLVTLKAGSVFGEISLLAvGGG 1039
Cdd:smart00100    1 LFKNLDAEELRELADALEPVRYPAGEVIIRQGDVGDSFYIIVSGEVEVykVLEDGEEQIVGTLGPGDFFGELALLT-NSR 79

                            90       100       110       120
                    ....*....|....*....|....*....|....*....|
gi 114205399   1040 NRRTANVVAHGFTNLFILDKKDLNEILVHYPESQKLLRKK 1079
Cdd:smart00100   80 RAASAAAVALELATLLRIDFRDFLQLLPELPQLLLELLLE 119
PLN03192 PLN03192
Voltage-dependent potassium channel; Provisional
 648-1034 3.52e-19

Voltage-dependent potassium channel; Provisional


Pssm-ID: 215625 [Multi-domain]  Cd Length: 823  Bit Score: 93.78  E-value: 3.52e-19
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 114205399  648 IDPLTNlMYVLWLFFVVMAWNWNCWLIPVRWAFPYQTPDNihHWLLMDYLCDLIYFLDI--TVF----QTRLQFvrggdI 721
Cdd:PLN03192   54 ISPMDS-RYRWWETLMVVLVAYSAWVYPFEVAFLNASPKR--GLEIADNVVDLFFAVDIvlTFFvayiDPRTQL-----L 125

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 114205399  722 ITDKKDMRNNYLkSRRFKMDLLSLLP-LDFLYLKVG---------VNPLLRLPRCLKYMAFFefnSRLESILSKAYVY-R 790
Cdd:PLN03192  126 VRDRKKIAVRYL-STWFLMDVASTIPfQALAYLITGtvklnlsysLLGLLRFWRLRRVKQLF---TRLEKDIRFSYFWiR 201

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 114205399  791 VIRTTAYLLYSLHLNSCLYYW-ASAYQGLGSThWVYDGVGN--------SYIRCYYFAVKTLITIG-----GLPDPKTLF 856
Cdd:PLN03192  202 CARLLSVTLFLVHCAGCLYYLiADRYPHQGKT-WIGAVIPNfretslwiRYISAIYWSITTMTTVGygdlhAVNTIEMIF 280

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 114205399  857 EIVFQLLNYftGVFAFsvMIGQMRDVVGAATAGQTYYRSCMDSTVKYMNFYKIPKSVQNRVKTWYEYTWHSQGmLDESEL 936
Cdd:PLN03192  281 IIFYMLFNL--GLTAY--LIGNMTNLVVEGTRRTMEFRNSIEAASNFVGRNRLPPRLKDQILAYMCLRFKAES-LNQQQL 355

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 114205399  937 MVQLPDKMRLDLAIDVNYNIVSKVALFQGCDRQMIFDMLKRLRSVVYLPNDYVCKKGEIGREMYIIQAGQVQV-LGGPDG 1015
Cdd:PLN03192  356 IDQLPKSICKSICQHLFLPVVEKVYLFKGVSREILLLLVTKMKAEYIPPREDVIMQNEAPDDVYIVVSGEVEIiDSEGEK 435

                         410
                  ....*....|....*....
gi 114205399 1016 KSVLVTLKAGSVFGEISLL 1034
Cdd:PLN03192  436 ERVVGTLGCGDIFGEVGAL 454
Ion_trans pfam00520
Ion transport protein; This family contains sodium, potassium and calcium ion channels. This ...
 658-881 1.56e-16

Ion transport protein; This family contains sodium, potassium and calcium ion channels. This family is 6 transmembrane helices in which the last two helices flank a loop which determines ion selectivity. In some sub-families (e.g. Na channels) the domain is repeated four times, whereas in others (e.g. K channels) the protein forms as a tetramer in the membrane.


Pssm-ID: 459842 [Multi-domain]  Cd Length: 238  Bit Score: 80.39  E-value: 1.56e-16
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 114205399   658 LWLFFVVMAWNWNCWLIPVRWAFPYQTPDNIHhWLLMDYLCDLIYFLDITvfqtrLQFVRGGDIItdkkdmrnNYLKSRR 737
Cdd:pfam00520    3 YFELFILLLILLNTIFLALETYFQPEEPLTTV-LEILDYVFTGIFTLEML-----LKIIAAGFKK--------RYFRSPW 68

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 114205399   738 FKMDLLSLLPLDFLYLKVGVNP--LLRLPRCLKYMAFFEFNSRLESIlsKAYVY---RVIRTTAYLLYSLHLNSCLYYWA 812
Cdd:pfam00520   69 NILDFVVVLPSLISLVLSSVGSlsGLRVLRLLRLLRLLRLIRRLEGL--RTLVNsliRSLKSLGNLLLLLLLFLFIFAII 146

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 114205399   813 sAYQGLGST--HWVYDGVGN----SYIRCYYFAVKTLITIgGLPD--PKTLFE-------IVFQLLNYFTGVFAFSVMIG 877
Cdd:pfam00520  147 -GYQLFGGKlkTWENPDNGRtnfdNFPNAFLWLFQTMTTE-GWGDimYDTIDGkgefwayIYFVSFIILGGFLLLNLFIA 224


                   ....
gi 114205399   878 QMRD 881
Cdd:pfam00520  225 VIID 228
cNMP_binding pfam00027
Cyclic nucleotide-binding domain; This domain sensor domain can bind cAMP, cGMP, c-di-GMP, ...
 981-1069 1.42e-15

Cyclic nucleotide-binding domain; This domain sensor domain can bind cAMP, cGMP, c-di-GMP, oxygen and 2-oxoglutarate (Matilla et. al., FEMS Microbiology Reviews, fuab043, 45, 2021, 1. https://doi.org/10.1093/femsre/fuab043).


Pssm-ID: 459637 [Multi-domain]  Cd Length: 89  Bit Score: 73.03  E-value: 1.42e-15
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 114205399   981 VVYLPNDYVCKKGEIGREMYIIQAGQVQVLG-GPDGKSVLV-TLKAGSVFGEISLLavgGGNRRTANVVAHGFTNLFILD 1058
Cdd:pfam00027    2 RSYKAGEVIFREGDPADSLYIVLSGKVKVYRtLEDGREQILaVLGPGDFFGELALL---GGEPRSATVVALTDSELLVIP 78

                           90
                   ....*....|.
gi 114205399  1059 KKDLNEILVHY 1069
Cdd:pfam00027   79 REDFLELLERD 89
Crp COG0664
cAMP-binding domain of CRP or a regulatory subunit of cAMP-dependent protein kinases [Signal ...
 963-1089 4.84e-14

cAMP-binding domain of CRP or a regulatory subunit of cAMP-dependent protein kinases [Signal transduction mechanisms];


Pssm-ID: 440428 [Multi-domain]  Cd Length: 207  Bit Score: 72.33  E-value: 4.84e-14
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 114205399  963 FQGCDRQMIFDMLKRLRSVVYLPNDYVCKKGEIGREMYIIQAGQVQVLG-GPDGKSVLV-TLKAGSVFGEISLLavgGGN 1040
Cdd:COG0664     1 FAGLSDEELEALLAHLELRTLKKGEVLFREGDPADHLYFVLSGLVKLYRiSEDGREQILgFLGPGDFFGELSLL---GGE 77

                          90       100       110       120       130
                  ....*....|....*....|....*....|....*....|....*....|
gi 114205399 1041 RRTANVVAHGFTNLFILDKKDLNEILVHYPE-SQKLLRKKARRMLRSNNK 1089
Cdd:COG0664    78 PSPATAEALEDSELLRIPREDLEELLERNPElARALLRLLARRLRQLQER 127
PRK10263 PRK10263
DNA translocase FtsK; Provisional
 167-311 4.75e-05

DNA translocase FtsK; Provisional


Pssm-ID: 236669 [Multi-domain]  Cd Length: 1355  Bit Score: 47.77  E-value: 4.75e-05
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 114205399  167 ERVLPQPP-KSSEV--------WRDEPAVATGAAS-DPAP---PGRPQEMGPKLQARETPSLPTPIPLQPKEEPKEAPAP 233
Cdd:PRK10263  338 EPVTQTPPvASVDVppaqptvaWQPVPGPQTGEPViAPAPegyPQQSQYAQPAVQYNEPLQQPVQPQQPYYAPAAEQPAQ 417

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 114205399  234 EPQPGSQAQT-----SSLPPTRDPARLVAWVLHRLEMAL-PQPVLHGKIGEQEPDSPGICDVQTISILPGGQVEPDLVLE 307
Cdd:PRK10263  418 QPYYAPAPEQpaqqpYYAPAPEQPVAGNAWQAEEQQSTFaPQSTYQTEQTYQQPAAQEPLYQQPQPVEQQPVVEPEPVVE 497


                  ....
gi 114205399  308 EVEP 311
Cdd:PRK10263  498 ETKP 501
PRK14950 PRK14950
DNA polymerase III subunits gamma and tau; Provisional
 190-320 4.34e-04

DNA polymerase III subunits gamma and tau; Provisional


Pssm-ID: 237864 [Multi-domain]  Cd Length: 585  Bit Score: 44.42  E-value: 4.34e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 114205399  190 AASDPAPPgrPQEMGPKLQAReTPSLPTPIPLQPkeePKeAPAPEPQPGSQAQTSSLPPTRDPARLVAwvlhrlemalpQ 269
Cdd:PRK14950  358 ALLVPVPA--PQPAKPTAAAP-SPVRPTPAPSTR---PK-AAAAANIPPKEPVRETATPPPVPPRPVA-----------P 419

                          90       100       110       120       130       140
                  ....*....|....*....|....*....|....*....|....*....|....*....|.
gi 114205399  270 PVLHGKigEQEPDSPGI---CDVQTISILPGGQVE-------PDLVLEEVEPPWEDAHQDV 320
Cdd:PRK14950  420 PVPHTP--ESAPKLTRAaipVDEKPKYTPPAPPKEeekaliaDGDVLEQLEAIWKQILRDV 478
PHA03247 PHA03247
large tegument protein UL36; Provisional
 115-253 6.36e-04

large tegument protein UL36; Provisional


Pssm-ID: 223021 [Multi-domain]  Cd Length: 3151  Bit Score: 44.54  E-value: 6.36e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 114205399  115 PQPVHSITEDPAQILGHGSTGDTGCTDEP-NEALEAqdtrpglRLLLWLeQNLERVL------PQPPKssevwrdePAVA 187
Cdd:PHA03247 2496 PDPGGGGPPDPDAPPAPSRLAPAILPDEPvGEPVHP-------RMLTWI-RGLEELAsddagdPPPPL--------PPAA 2559

                          90       100       110       120       130       140       150
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 114205399  188 TGAASD---PAPPGRPQEMGPKLQARET-PSLP----TP-IPLQPKEEPKEAPAPEPQPGSQAQTSSLPPTRDPA 253
Cdd:PHA03247 2560 PPAAPDrsvPPPRPAPRPSEPAVTSRARrPDAPpqsaRPrAPVDDRGDPRGPAPPSPLPPDTHAPDPPPPSPSPA 2634
PHA03378 PHA03378
EBNA-3B; Provisional
 172-275 7.73e-04

EBNA-3B; Provisional


Pssm-ID: 223065 [Multi-domain]  Cd Length: 991  Bit Score: 43.90  E-value: 7.73e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 114205399  172 QPPKSSEVWRDEPAVATGAASDPAPPGRPQEMGPKLQARETPSLPTPIPLQPKEEPKEAPAPEPQPGSQAQTSSLPPtRD 251
Cdd:PHA03378  735 RPPAAAPGRARPPAAAPGRARPPAAAPGRARPPAAAPGAPTPQPPPQAPPAPQQRPRGAPTPQPPPQAGPTSMQLMP-RA 813

                          90       100
                  ....*....|....*....|....
gi 114205399  252 PARLVAWVLHRLEMALPQPVLHGK 275
Cdd:PHA03378  814 APGQQGPTKQILRQLLTGGVKRGR 837
PRK14948 PRK14948
DNA polymerase III subunit gamma/tau;
160-264 1.10e-03

DNA polymerase III subunit gamma/tau;


Pssm-ID: 237862 [Multi-domain]  Cd Length: 620  Bit Score: 43.03  E-value: 1.10e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 114205399  160 LWLEQNLERVLPQPPKSSEVWRDEPAVATGAASDPAPPGRPQEMGPK-LQARETPSLPTPIPLQPKEEPKEAPAPEPQPG 238
Cdd:PRK14948  350 LWLEVTLLGLLPSAFISEIANASAPANPTPAPNPSPPPAPIQPSAPKtKQAATTPSPPPAKASPPIPVPAEPTEPSPTPP 429

                          90       100
                  ....*....|....*....|....*.
gi 114205399  239 SQAQTSslPPTRDPARLVAWVLHRLE 264
Cdd:PRK14948  430 ANAANA--PPSLNLEELWQQILAKLE 453
PRK10263 PRK10263
DNA translocase FtsK; Provisional
 185-344 1.19e-03

DNA translocase FtsK; Provisional


Pssm-ID: 236669 [Multi-domain]  Cd Length: 1355  Bit Score: 43.54  E-value: 1.19e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 114205399  185 AVATGAASDPAPPGRPQEMGPKLQARETP-SLPT----PIPLQPKEEPKEAPAPE---PQP-GSQAQTSSLPPTRDPARL 255
Cdd:PRK10263  324 AAATTATQSWAAPVEPVTQTPPVASVDVPpAQPTvawqPVPGPQTGEPVIAPAPEgypQQSqYAQPAVQYNEPLQQPVQP 403

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 114205399  256 VAWVLHRLEMALPQPVLHGKIGEQ--EPDSPGICDVQTISILPGGQVEPDLVLEE--VEPPWEDAHQDVSTSPQgtEVVP 331
Cdd:PRK10263  404 QQPYYAPAAEQPAQQPYYAPAPEQpaQQPYYAPAPEQPVAGNAWQAEEQQSTFAPqsTYQTEQTYQQPAAQEPL--YQQP 481

                         170
                  ....*....|...
gi 114205399  332 AYEEENKAVEKMP 344
Cdd:PRK10263  482 QPVEQQPVVEPEP 494
PLN02868 PLN02868
acyl-CoA thioesterase family protein
 975-1048 1.84e-03

acyl-CoA thioesterase family protein


Pssm-ID: 178459 [Multi-domain]  Cd Length: 413  Bit Score: 42.40  E-value: 1.84e-03
                          10        20        30        40        50        60        70
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 114205399  975 LKRLRSVV----YLPNDYVCKKGEIGREMYIIQAGQVQVLG-GPDGKSVLVTLKAGSVFGEISLlavggGNRRTANVVA 1048
Cdd:PLN02868   24 LKKIAEVVvpkrYGKGEYVVREGEPGDGLYFIWKGEAEVSGpAEEESRPEFLLKRYDYFGYGLS-----GSVHSADVVA 97
PHA03247 PHA03247
large tegument protein UL36; Provisional
 171-253 2.07e-03

large tegument protein UL36; Provisional


Pssm-ID: 223021 [Multi-domain]  Cd Length: 3151  Bit Score: 42.62  E-value: 2.07e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 114205399  171 PQPPKSSEVWrdepavatgaASDPAPPGRPQEMGPKLQARETPSLPTPiplqpkeePKEAPAPEPQPGSQAQtssLPPTR 250
Cdd:PHA03247 2889 PAVSRSTESF----------ALPPDQPERPPQPQAPPPPQPQPQPPPP--------PQPQPPPPPPPRPQPP---LAPTT 2947


                  ...
gi 114205399  251 DPA 253
Cdd:PHA03247 2948 DPA 2950
PHA03247 PHA03247
large tegument protein UL36; Provisional
 171-247 2.37e-03

large tegument protein UL36; Provisional


Pssm-ID: 223021 [Multi-domain]  Cd Length: 3151  Bit Score: 42.62  E-value: 2.37e-03
                          10        20        30        40        50        60        70
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 114205399  171 PQPPKSSEVWRdePAVATGAASDPAPPGRPQEM-GPKLQARETPSLPTPIPLQPKEEPKEAPAPEPQPGSQAQTSSLP 247
Cdd:PHA03247 2878 PARPPVRRLAR--PAVSRSTESFALPPDQPERPpQPQAPPPPQPQPQPPPPPQPQPPPPPPPRPQPPLAPTTDPAGAG 2953
PHA03247 PHA03247
large tegument protein UL36; Provisional
 190-314 3.05e-03

large tegument protein UL36; Provisional


Pssm-ID: 223021 [Multi-domain]  Cd Length: 3151  Bit Score: 42.23  E-value: 3.05e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 114205399  190 AASDPAPPGRP--QEMGPKLQARETPSLPTP-IPLQPKEEPKEAPAPEPQPGSQAQTSSLPPTRDPARlvawvlhrlema 266
Cdd:PHA03247 2871 PAAKPAAPARPpvRRLARPAVSRSTESFALPpDQPERPPQPQAPPPPQPQPQPPPPPQPQPPPPPPPR------------ 2938

                          90       100       110       120       130
                  ....*....|....*....|....*....|....*....|....*....|.
gi 114205399  267 lPQPVLH---GKIGEQEPdSPGICDVQTISILPGGQVEPDLVLEEVEPPWE 314
Cdd:PHA03247 2939 -PQPPLApttDPAGAGEP-SGAVPQPWLGALVPGRVAVPRFRVPQPAPSRE 2987
COG5373 COG5373
Uncharacterized membrane protein [Function unknown];
156-258 3.47e-03

Uncharacterized membrane protein [Function unknown];


Pssm-ID: 444140 [Multi-domain]  Cd Length: 854  Bit Score: 41.91  E-value: 3.47e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 114205399  156 LRLLLWLEQNLERVlpqppkSSEVWRDEPAVATGAASDPAPPGRPQEMGPKLQARETPSLPTPIPLQPKEEPKEAPAPEP 235
Cdd:COG5373    13 LALLVGLLGRVARL------RRRVEELEAELAEAAEAASAPAEPEPEAAAAATAAAPEAAPAPVPEAPAAPPAAAEAPAP 86

                          90       100
                  ....*....|....*....|...
gi 114205399  236 QPGSQAQTSslPPTRDPARLVAW 258
Cdd:COG5373    87 AAAAPPAEA--EPAAAPAAASSF 107
PRK14971 PRK14971
DNA polymerase III subunit gamma/tau;
166-254 4.26e-03

DNA polymerase III subunit gamma/tau;


Pssm-ID: 237874 [Multi-domain]  Cd Length: 614  Bit Score: 41.30  E-value: 4.26e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 114205399  166 LERVLPQPPKSSEVWRDEPAVATGAASDPAPPGRPQEMGPKLQARETPSLPTPIPlQPKEEPKEAP---APEPQPGSQAQ 242
Cdd:PRK14971  384 TQPAAAPQPSAAAAASPSPSQSSAAAQPSAPQSATQPAGTPPTVSVDPPAAVPVN-PPSTAPQAVRpaqFKEEKKIPVSK 462

                          90
                  ....*....|...
gi 114205399  243 TSSL-PPTRDPAR 254
Cdd:PRK14971  463 VSSLgPSTLRPIQ 475
PRK11633 PRK11633
cell division protein DedD; Provisional
 170-253 8.48e-03

cell division protein DedD; Provisional


Pssm-ID: 236940 [Multi-domain]  Cd Length: 226  Bit Score: 39.22  E-value: 8.48e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 114205399  170 LP-QPPkssevwrdEPAVATGAASDPAPPGRPQemgPKLQARETPSLPTPIPL-QPKEEPKEAPAPEPQPGSQAQTSSLP 247
Cdd:PRK11633   63 LPtQPP--------EGAAEAVRAGDAAAPSLDP---ATVAPPNTPVEPEPAPVePPKPKPVEKPKPKPKPQQKVEAPPAP 131


                  ....*..
gi 114205399  248 -PTRDPA 253
Cdd:PRK11633  132 kPEPKPV 138
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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