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Conserved domains on  [gi|1279652352|ref|NP_001345234|]
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UPF0729 protein C18orf32 homolog isoform 1 [Mus musculus]

Protein Classification

DUF4512 domain-containing protein( domain architecture ID 142592)

DUF4512 domain-containing protein similar to Homo sapiens UPF0729 protein C18orf32, also known as NF-kappa-B-activating protein 200, which may activate the NF-kappa-B signaling pathway

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
DUF4512 super family cl20855
Domain of unknown function (DUF4512); This family of proteins is found in eukaryotes. Proteins ...
 2-59 7.33e-13

Domain of unknown function (DUF4512); This family of proteins is found in eukaryotes. Proteins in this family are typically between 74 and 104 amino acids in length. There are two completely conserved residues (C and P) that may be functionally important.


The actual alignment was detected with superfamily member pfam14975:

Pssm-ID: 405640  Cd Length: 103  Bit Score: 57.94  E-value: 7.33e-13
                          10        20        30        40        50        60
                  ....*....|....*....|....*....|....*....|....*....|....*....|..
gi 1279652352   2 VCIPCIVIPVLLWIFKKFLEPYIY----PVVSRIWPKKAVQQSGDknmSKVDCKGAGTNGLP 59
Cdd:pfam14975   1 VCVPCFIIPLLLYIWHKFVQPIILrywnPWEKKDADGNVIKAGPE---FPFECKGGVCPFVP 59
 
Name Accession Description Interval E-value
DUF4512 pfam14975
Domain of unknown function (DUF4512); This family of proteins is found in eukaryotes. Proteins ...
 2-59 7.33e-13

Domain of unknown function (DUF4512); This family of proteins is found in eukaryotes. Proteins in this family are typically between 74 and 104 amino acids in length. There are two completely conserved residues (C and P) that may be functionally important.


Pssm-ID: 405640  Cd Length: 103  Bit Score: 57.94  E-value: 7.33e-13
                          10        20        30        40        50        60
                  ....*....|....*....|....*....|....*....|....*....|....*....|..
gi 1279652352   2 VCIPCIVIPVLLWIFKKFLEPYIY----PVVSRIWPKKAVQQSGDknmSKVDCKGAGTNGLP 59
Cdd:pfam14975   1 VCVPCFIIPLLLYIWHKFVQPIILrywnPWEKKDADGNVIKAGPE---FPFECKGGVCPFVP 59
 
Name Accession Description Interval E-value
DUF4512 pfam14975
Domain of unknown function (DUF4512); This family of proteins is found in eukaryotes. Proteins ...
 2-59 7.33e-13

Domain of unknown function (DUF4512); This family of proteins is found in eukaryotes. Proteins in this family are typically between 74 and 104 amino acids in length. There are two completely conserved residues (C and P) that may be functionally important.


Pssm-ID: 405640  Cd Length: 103  Bit Score: 57.94  E-value: 7.33e-13
                          10        20        30        40        50        60
                  ....*....|....*....|....*....|....*....|....*....|....*....|..
gi 1279652352   2 VCIPCIVIPVLLWIFKKFLEPYIY----PVVSRIWPKKAVQQSGDknmSKVDCKGAGTNGLP 59
Cdd:pfam14975   1 VCVPCFIIPLLLYIWHKFVQPIILrywnPWEKKDADGNVIKAGPE---FPFECKGGVCPFVP 59
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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