NCBI Home Page NCBI Site Search page NCBI Guide that lists and describes the NCBI resources
Conserved domains on  [gi|1391723720|ref|NP_001350507|]
View 

male-enhanced antigen 1 isoform 3 [Homo sapiens]

Protein Classification

Graphical summary

 Zoom to residue level

show extra options »

Show site features     Horizontal zoom: ×

List of domain hits

 Name Accession Description Interval E-value
MEA1 pfam06910
Male enhanced antigen 1 (MEA1); This family consists of several mammalian male enhanced ...
 69-184 7.24e-34

Male enhanced antigen 1 (MEA1); This family consists of several mammalian male enhanced antigen 1 (MEA1) proteins. The Mea-1 gene is found to be localized in primary and secondary spermatocytes and spermatids, but the protein products are detected only in spermatids. Intensive transcription of Mea-1 gene and specific localization of the gene product suggest that Mea-1 may play a important role in the late stage of spermatogenesis.


:

Pssm-ID: 429188  Cd Length: 125  Bit Score: 116.44  E-value: 7.24e-34
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1391723720  69 AGYSYQPLNQDPEQEE--VELAPVGDGDVVADIQDRIQALGLHLPDPPLESEDEDEEGA-------TALNNHSSIPMDPE 139
Cdd:pfam06910   1 GGYGYQPLNQDPEDEEpmRDDDDDDEEESGFGESETPSVMGLEPPPPDSDPDIEEEDESevrevwsAPRPNESSIPMDAE 80

                          90       100       110       120
                  ....*....|....*....|....*....|....*....|....*
gi 1391723720 140 HVELVKRTMAGVSLPAPGVPAWAREISDAQWEDVVQKALQARQAS 184
Cdd:pfam06910  81 KVELVKSTMAGIKLPSTAIPAWAREISEEQWKQQLLQRIQQRQQA 125
 
Name Accession Description Interval E-value
MEA1 pfam06910
Male enhanced antigen 1 (MEA1); This family consists of several mammalian male enhanced ...
 69-184 7.24e-34

Male enhanced antigen 1 (MEA1); This family consists of several mammalian male enhanced antigen 1 (MEA1) proteins. The Mea-1 gene is found to be localized in primary and secondary spermatocytes and spermatids, but the protein products are detected only in spermatids. Intensive transcription of Mea-1 gene and specific localization of the gene product suggest that Mea-1 may play a important role in the late stage of spermatogenesis.


Pssm-ID: 429188  Cd Length: 125  Bit Score: 116.44  E-value: 7.24e-34
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1391723720  69 AGYSYQPLNQDPEQEE--VELAPVGDGDVVADIQDRIQALGLHLPDPPLESEDEDEEGA-------TALNNHSSIPMDPE 139
Cdd:pfam06910   1 GGYGYQPLNQDPEDEEpmRDDDDDDEEESGFGESETPSVMGLEPPPPDSDPDIEEEDESevrevwsAPRPNESSIPMDAE 80

                          90       100       110       120
                  ....*....|....*....|....*....|....*....|....*
gi 1391723720 140 HVELVKRTMAGVSLPAPGVPAWAREISDAQWEDVVQKALQARQAS 184
Cdd:pfam06910  81 KVELVKSTMAGIKLPSTAIPAWAREISEEQWKQQLLQRIQQRQQA 125
 
Name Accession Description Interval E-value
MEA1 pfam06910
Male enhanced antigen 1 (MEA1); This family consists of several mammalian male enhanced ...
 69-184 7.24e-34

Male enhanced antigen 1 (MEA1); This family consists of several mammalian male enhanced antigen 1 (MEA1) proteins. The Mea-1 gene is found to be localized in primary and secondary spermatocytes and spermatids, but the protein products are detected only in spermatids. Intensive transcription of Mea-1 gene and specific localization of the gene product suggest that Mea-1 may play a important role in the late stage of spermatogenesis.


Pssm-ID: 429188  Cd Length: 125  Bit Score: 116.44  E-value: 7.24e-34
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1391723720  69 AGYSYQPLNQDPEQEE--VELAPVGDGDVVADIQDRIQALGLHLPDPPLESEDEDEEGA-------TALNNHSSIPMDPE 139
Cdd:pfam06910   1 GGYGYQPLNQDPEDEEpmRDDDDDDEEESGFGESETPSVMGLEPPPPDSDPDIEEEDESevrevwsAPRPNESSIPMDAE 80

                          90       100       110       120
                  ....*....|....*....|....*....|....*....|....*
gi 1391723720 140 HVELVKRTMAGVSLPAPGVPAWAREISDAQWEDVVQKALQARQAS 184
Cdd:pfam06910  81 KVELVKSTMAGIKLPSTAIPAWAREISEEQWKQQLLQRIQQRQQA 125
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
Help | Disclaimer | Write to the Help Desk
NCBI | NLM | NIH