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Conserved domains on  [gi|1394533522|ref|NP_001350872|]
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angiomotin-like protein 2 isoform 4 [Homo sapiens]

Protein Classification

Smc and Angiomotin_C domain-containing protein( domain architecture ID 10573751)

Smc and Angiomotin_C domain-containing protein

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
Angiomotin_C pfam12240
Angiomotin C terminal; This domain family is found in eukaryotes, and is typically between 197 ...
 482-687 8.11e-94

Angiomotin C terminal; This domain family is found in eukaryotes, and is typically between 197 and 211 amino acids in length. This family is the C terminal region of angiomotin. Angiomotin regulates the action of angiogenesis inhibitor angiostatin. The C terminal region of angiomotin appears to be involved in directing the protein chemotactically.


:

Pssm-ID: 463503 [Multi-domain]  Cd Length: 200  Bit Score: 291.29  E-value: 8.11e-94
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1394533522 482 YVEKVERLQQALGQLQAACEKREQLELRLRTRLEQELKALRAQQRQAGAPGGSSGsggspELSALRLSEQLREKEEQILA 561
Cdd:pfam12240   1 YVEKVERLQQALAQLQAACEKREQLELRLRTRLEQELKSLRAQQRQGGSQGSGPS-----EYSAPALMELLREKEERILA 75

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1394533522 562 LEADMTKWEQKYLEERAMRQFAMDAAATAAAQRDTTLIRHSPQPSPSSSFNEGLLTGGHRHQEMESRLKVLHAQILEKDA 641
Cdd:pfam12240  76 LEADMTKWEQKYLEESTMRQFAMDAAATAAAQRDTTIINHSPRHSYDSSFNEELLLANRRCQEMENRIKNLHAQILEKDA 155

                         170       180       190       200
                  ....*....|....*....|....*....|....*....|....*.
gi 1394533522 642 VIKVLQQRSRRDPGKAIQGSLRPAKSVPSVFaAAAAGTQGWQGLSS 687
Cdd:pfam12240 156 MIKVLQQRSRKDPGKTDQQSLRPARSVPSIS-AAATGLHSRQTSLS 200
Smc super family cl34174
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ...
 312-581 2.81e-13

Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];


The actual alignment was detected with superfamily member COG1196:

Pssm-ID: 440809 [Multi-domain]  Cd Length: 983  Bit Score: 73.82  E-value: 2.81e-13
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1394533522 312 AQMEAVLRENARLQRDNERLQRELES-SAEKAGRIEKLESEIQRLSEAHESLTRASSKREALEKtmrnkmdsEMRRLQDF 390
Cdd:COG1196   239 AELEELEAELEELEAELEELEAELAElEAELEELRLELEELELELEEAQAEEYELLAELARLEQ--------DIARLEER 310

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1394533522 391 NRDLRERLESANRRLASKTQEAQAGSQDMVAKLLAQSYEQQQEQEKLEREMALLRGAIEDQRRRAELLEQALGNAQGRAA 470
Cdd:COG1196   311 RRELEERLEELEEELAELEEELEELEEELEELEEELEEAEEELEEAEAELAEAEEALLEAEAELAEAEEELEELAEELLE 390

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1394533522 471 RAEEELRKKQAYVEKVERLQQALGQLQAACEKREQLELRLRTRLEQELKALRAQQRQAGAPGGSSGSGGSPELSALRLSE 550
Cdd:COG1196   391 ALRAAAELAAQLEELEEAEEALLERLERLEEELEELEEALAELEEEEEEEEEALEEAAEEEAELEEEEEALLELLAELLE 470

                         250       260       270
                  ....*....|....*....|....*....|.
gi 1394533522 551 QLREKEEQILALEADMTKWEQKYLEERAMRQ 581
Cdd:COG1196   471 EAALLEAALAELLEELAEAAARLLLLLEAEA 501
 
Name Accession Description Interval E-value
Angiomotin_C pfam12240
Angiomotin C terminal; This domain family is found in eukaryotes, and is typically between 197 ...
 482-687 8.11e-94

Angiomotin C terminal; This domain family is found in eukaryotes, and is typically between 197 and 211 amino acids in length. This family is the C terminal region of angiomotin. Angiomotin regulates the action of angiogenesis inhibitor angiostatin. The C terminal region of angiomotin appears to be involved in directing the protein chemotactically.


Pssm-ID: 463503 [Multi-domain]  Cd Length: 200  Bit Score: 291.29  E-value: 8.11e-94
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1394533522 482 YVEKVERLQQALGQLQAACEKREQLELRLRTRLEQELKALRAQQRQAGAPGGSSGsggspELSALRLSEQLREKEEQILA 561
Cdd:pfam12240   1 YVEKVERLQQALAQLQAACEKREQLELRLRTRLEQELKSLRAQQRQGGSQGSGPS-----EYSAPALMELLREKEERILA 75

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1394533522 562 LEADMTKWEQKYLEERAMRQFAMDAAATAAAQRDTTLIRHSPQPSPSSSFNEGLLTGGHRHQEMESRLKVLHAQILEKDA 641
Cdd:pfam12240  76 LEADMTKWEQKYLEESTMRQFAMDAAATAAAQRDTTIINHSPRHSYDSSFNEELLLANRRCQEMENRIKNLHAQILEKDA 155

                         170       180       190       200
                  ....*....|....*....|....*....|....*....|....*.
gi 1394533522 642 VIKVLQQRSRRDPGKAIQGSLRPAKSVPSVFaAAAAGTQGWQGLSS 687
Cdd:pfam12240 156 MIKVLQQRSRKDPGKTDQQSLRPARSVPSIS-AAATGLHSRQTSLS 200
Smc COG1196
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ...
 312-581 2.81e-13

Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 440809 [Multi-domain]  Cd Length: 983  Bit Score: 73.82  E-value: 2.81e-13
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1394533522 312 AQMEAVLRENARLQRDNERLQRELES-SAEKAGRIEKLESEIQRLSEAHESLTRASSKREALEKtmrnkmdsEMRRLQDF 390
Cdd:COG1196   239 AELEELEAELEELEAELEELEAELAElEAELEELRLELEELELELEEAQAEEYELLAELARLEQ--------DIARLEER 310

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1394533522 391 NRDLRERLESANRRLASKTQEAQAGSQDMVAKLLAQSYEQQQEQEKLEREMALLRGAIEDQRRRAELLEQALGNAQGRAA 470
Cdd:COG1196   311 RRELEERLEELEEELAELEEELEELEEELEELEEELEEAEEELEEAEAELAEAEEALLEAEAELAEAEEELEELAEELLE 390

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1394533522 471 RAEEELRKKQAYVEKVERLQQALGQLQAACEKREQLELRLRTRLEQELKALRAQQRQAGAPGGSSGSGGSPELSALRLSE 550
Cdd:COG1196   391 ALRAAAELAAQLEELEEAEEALLERLERLEEELEELEEALAELEEEEEEEEEALEEAAEEEAELEEEEEALLELLAELLE 470

                         250       260       270
                  ....*....|....*....|....*....|.
gi 1394533522 551 QLREKEEQILALEADMTKWEQKYLEERAMRQ 581
Cdd:COG1196   471 EAALLEAALAELLEELAEAAARLLLLLEAEA 501
Smc COG1196
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ...
 309-704 7.08e-11

Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 440809 [Multi-domain]  Cd Length: 983  Bit Score: 66.11  E-value: 7.08e-11
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1394533522 309 AHLAQMEAVLRE-NARLqrdnERLQRElessAEKAGRIEKLESEIQ---------RLSEAHESLTRASSKREALEKTmRN 378
Cdd:COG1196   186 ENLERLEDILGElERQL----EPLERQ----AEKAERYRELKEELKeleaellllKLRELEAELEELEAELEELEAE-LE 256

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1394533522 379 KMDSEMRRLQDFNRDLRERLESANRRLASKTQEAQAGSQDmVAKLLAQSYEQQQEQEKLEREMALLRGAIEDQRRRAELL 458
Cdd:COG1196   257 ELEAELAELEAELEELRLELEELELELEEAQAEEYELLAE-LARLEQDIARLEERRRELEERLEELEEELAELEEELEEL 335

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1394533522 459 EQALGNAQGRAARAEEELRKKQayvekvERLQQALGQLQAACEKREQLELRLRTRLEQELKALRAQQRQAGAPGGSSGSG 538
Cdd:COG1196   336 EEELEELEEELEEAEEELEEAE------AELAEAEEALLEAEAELAEAEEELEELAEELLEALRAAAELAAQLEELEEAE 409

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1394533522 539 GSPELSALRLSEQLREKEEQILALEADMTKWEQKYLEERAMRQFAMDAAATAAAQRDTTLIRHSPQPSPSSSFNEGLLtg 618
Cdd:COG1196   410 EALLERLERLEEELEELEEALAELEEEEEEEEEALEEAAEEEAELEEEEEALLELLAELLEEAALLEAALAELLEELA-- 487

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1394533522 619 ghRHQEMESRLKVLHAQILEKDAVIKVLQQRSRRDPGKAIQGSLRPAKSVPSVFAAAAAGTQGWQGLSSSERQTADAPAR 698
Cdd:COG1196   488 --EAAARLLLLLEAEADYEGFLEGVKAALLLAGLRGLAGAVAVLIGVEAAYEAALEAALAAALQNIVVEDDEVAAAAIEY 565


                  ....*.
gi 1394533522 699 LTTDRA 704
Cdd:COG1196   566 LKAAKA 571
SMC_prok_A TIGR02169
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of ...
 312-578 1.01e-08

chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. It is found in a single copy and is homodimeric in prokaryotes, but six paralogs (excluded from this family) are found in eukarotes, where SMC proteins are heterodimeric. This family represents the SMC protein of archaea and a few bacteria (Aquifex, Synechocystis, etc); the SMC of other bacteria is described by TIGR02168. The N- and C-terminal domains of this protein are well conserved, but the central hinge region is skewed in composition and highly divergent. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274009 [Multi-domain]  Cd Length: 1164  Bit Score: 58.93  E-value: 1.01e-08
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1394533522  312 AQMEAVLRENARLQRDNERLQRELESSAEK----AGRIEKLESEIQRLSEAHESLTRASSK-REALEKTMRN-------K 379
Cdd:TIGR02169  716 RKIGEIEKEIEQLEQEEEKLKERLEELEEDlsslEQEIENVKSELKELEARIEELEEDLHKlEEALNDLEARlshsripE 795

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1394533522  380 MDSEMRRLQDFNRDLRERLESANRRLASKTQEAQAgSQDMVAKLLAQSYEQQQEQEKLEREMALLRGAIEDQRRRAELLE 459
Cdd:TIGR02169  796 IQAELSKLEEEVSRIEARLREIEQKLNRLTLEKEY-LEKEIQELQEQRIDLKEQIKSIEKEIENLNGKKEELEEELEELE 874

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1394533522  460 QALGNAQGRAARAEEELRKKQAyveKVERLQQALGQLQAACEKREQLELRLRTRLEqelkALRAQQRQAGAPGGSSGSGG 539
Cdd:TIGR02169  875 AALRDLESRLGDLKKERDELEA---QLRELERKIEELEAQIEKKRKRLSELKAKLE----ALEEELSEIEDPKGEDEEIP 947

                          250       260       270
                   ....*....|....*....|....*....|....*....
gi 1394533522  540 SPELSALRLSEQLREKEEQILALEADMTKWEQKYLEERA 578
Cdd:TIGR02169  948 EEELSLEDVQAELQRVEEEIRALEPVNMLAIQEYEEVLK 986
PTZ00121 PTZ00121
MAEBL; Provisional
 315-580 1.82e-05

MAEBL; Provisional


Pssm-ID: 173412 [Multi-domain]  Cd Length: 2084  Bit Score: 48.60  E-value: 1.82e-05
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1394533522  315 EAVLRENARLQRDNERLQRELESSAEKAGRIEKLESEIQRLSEAHESLTRASS---KREALEKTMRNKMDSEMRRLQDfN 391
Cdd:PTZ00121  1455 EAKKAEEAKKKAEEAKKADEAKKKAEEAKKADEAKKKAEEAKKKADEAKKAAEakkKADEAKKAEEAKKADEAKKAEE-A 1533

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1394533522  392 RDLRERLESANRRLASKTQEAQAgsqdmVAKLLAQSYEQQQEQEKLEREMALLRGAIEDQ---RRRAELLEQALGNAQGR 468
Cdd:PTZ00121  1534 KKADEAKKAEEKKKADELKKAEE-----LKKAEEKKKAEEAKKAEEDKNMALRKAEEAKKaeeARIEEVMKLYEEEKKMK 1608

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1394533522  469 A--ARAEEELRKKQAYVEKVERLQQALGQLQA--ACEKREQLELR-----LRTRLEQELKALRAQQRQAGAPGGSSGSGG 539
Cdd:PTZ00121  1609 AeeAKKAEEAKIKAEELKKAEEEKKKVEQLKKkeAEEKKKAEELKkaeeeNKIKAAEEAKKAEEDKKKAEEAKKAEEDEK 1688

                          250       260       270       280
                   ....*....|....*....|....*....|....*....|...
gi 1394533522  540 SPELSALRLSEQLREKEEQILALEADMTKWEQ--KYLEERAMR 580
Cdd:PTZ00121  1689 KAAEALKKEAEEAKKAEELKKKEAEEKKKAEElkKAEEENKIK 1731
SMC_prok_B TIGR02168
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...
 322-649 2.35e-05

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274008 [Multi-domain]  Cd Length: 1179  Bit Score: 48.13  E-value: 2.35e-05
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1394533522  322 ARLQRDNERLQRELEssaekagrIEKLESEIQRLSEAHESLTRAsskrealektmRNKMDSEMRRLQDFNRDLRERLESA 401
Cdd:TIGR02168  664 GSAKTNSSILERRRE--------IEELEEKIEELEEKIAELEKA-----------LAELRKELEELEEELEQLRKELEEL 724

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1394533522  402 NRRLASKTQEAQAGSQdmvakllaqsyeqqqEQEKLEREMALLRGAIEDQRRRAELLEQALGNAQGRAARAEEELRKKQA 481
Cdd:TIGR02168  725 SRQISALRKDLARLEA---------------EVEQLEERIAQLSKELTELEAEIEELEERLEEAEEELAEAEAEIEELEA 789

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1394533522  482 yveKVERLQQALGQLqaacekREQLElrlrtRLEQELKALR-AQQRQAGAPGGSSGSGGSPELSALRLSEQLREKEEQIL 560
Cdd:TIGR02168  790 ---QIEQLKEELKAL------REALD-----ELRAELTLLNeEAANLRERLESLERRIAATERRLEDLEEQIEELSEDIE 855

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1394533522  561 ALEADMTkwEQKYLEERAMRQFAMDAAATAAAQRDTTLIRHspqpsPSSSFNEGLLTGGHRHQEMESRLKVLHAQILEKD 640
Cdd:TIGR02168  856 SLAAEIE--ELEELIEELESELEALLNERASLEEALALLRS-----ELEELSEELRELESKRSELRRELEELREKLAQLE 928


                   ....*....
gi 1394533522  641 AVIKVLQQR 649
Cdd:TIGR02168  929 LRLEGLEVR 937
DUF3584 pfam12128
Protein of unknown function (DUF3584); This protein is found in bacteria and eukaryotes. ...
 312-527 5.66e-05

Protein of unknown function (DUF3584); This protein is found in bacteria and eukaryotes. Proteins in this family are typically between 943 to 1234 amino acids in length. This family contains a P-loop motif suggesting it is a nucleotide binding protein. It may be involved in replication.


Pssm-ID: 432349 [Multi-domain]  Cd Length: 1191  Bit Score: 46.76  E-value: 5.66e-05
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1394533522  312 AQMEAVLRENARLQRDNERLQR----ELESSAEKAGRIEKLESEIQRLSEAHESLTRASSKREALEKTMRNKMDSEMRR- 386
Cdd:pfam12128  312 AADAAVAKDRSELEALEDQHGAfldaDIETAAADQEQLPSWQSELENLEERLKALTGKHQDVTAKYNRRRSKIKEQNNRd 391

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1394533522  387 LQDFNRDLRERLESANRRLASKTQEAQAGSQDMVAKLlaqsyeqqqeqekleremallRGAIEDQRRRAELLEQALGNAQ 466
Cdd:pfam12128  392 IAGIKDKLAKIREARDRQLAVAEDDLQALESELREQL---------------------EAGKLEFNEEEYRLKSRLGELK 450

                          170       180       190       200       210       220
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 1394533522  467 GRAARA---EEELRKKQAYVEKVERLQQALGQLQAACEKREQLELRLRTRLEQELKAL-----RAQQRQ 527
Cdd:pfam12128  451 LRLNQAtatPELLLQLENFDERIERAREEQEAANAEVERLQSELRQARKRRDQASEALrqasrRLEERQ 519
OmpH smart00935
Outer membrane protein (OmpH-like); This family includes outer membrane proteins such as OmpH ...
 311-412 2.98e-03

Outer membrane protein (OmpH-like); This family includes outer membrane proteins such as OmpH among others. Skp (OmpH) has been characterized as a molecular chaperone that interacts with unfolded proteins as they emerge in the periplasm from the Sec translocation machinery.


Pssm-ID: 214922 [Multi-domain]  Cd Length: 140  Bit Score: 38.72  E-value: 2.98e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1394533522  311 LAQMEAVLRENARLQRDNERLQRELESSAEKagrIEKLESEIQRlseahESLTRASSKREALEKTMRNKMDSEMRRLQDF 390
Cdd:smart00935  10 LQESPAGKAAQKQLEKEFKKRQAELEKLEKE---LQKLKEKLQK-----DAATLSEAAREKKEKELQKKVQEFQRKQQKL 81

                           90       100
                   ....*....|....*....|..
gi 1394533522  391 NRDLRERLESANRRLASKTQEA 412
Cdd:smart00935  82 QQDLQKRQQEELQKILDKINKA 103
 
Name Accession Description Interval E-value
Angiomotin_C pfam12240
Angiomotin C terminal; This domain family is found in eukaryotes, and is typically between 197 ...
 482-687 8.11e-94

Angiomotin C terminal; This domain family is found in eukaryotes, and is typically between 197 and 211 amino acids in length. This family is the C terminal region of angiomotin. Angiomotin regulates the action of angiogenesis inhibitor angiostatin. The C terminal region of angiomotin appears to be involved in directing the protein chemotactically.


Pssm-ID: 463503 [Multi-domain]  Cd Length: 200  Bit Score: 291.29  E-value: 8.11e-94
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1394533522 482 YVEKVERLQQALGQLQAACEKREQLELRLRTRLEQELKALRAQQRQAGAPGGSSGsggspELSALRLSEQLREKEEQILA 561
Cdd:pfam12240   1 YVEKVERLQQALAQLQAACEKREQLELRLRTRLEQELKSLRAQQRQGGSQGSGPS-----EYSAPALMELLREKEERILA 75

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1394533522 562 LEADMTKWEQKYLEERAMRQFAMDAAATAAAQRDTTLIRHSPQPSPSSSFNEGLLTGGHRHQEMESRLKVLHAQILEKDA 641
Cdd:pfam12240  76 LEADMTKWEQKYLEESTMRQFAMDAAATAAAQRDTTIINHSPRHSYDSSFNEELLLANRRCQEMENRIKNLHAQILEKDA 155

                         170       180       190       200
                  ....*....|....*....|....*....|....*....|....*.
gi 1394533522 642 VIKVLQQRSRRDPGKAIQGSLRPAKSVPSVFaAAAAGTQGWQGLSS 687
Cdd:pfam12240 156 MIKVLQQRSRKDPGKTDQQSLRPARSVPSIS-AAATGLHSRQTSLS 200
Smc COG1196
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ...
 312-581 2.81e-13

Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 440809 [Multi-domain]  Cd Length: 983  Bit Score: 73.82  E-value: 2.81e-13
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1394533522 312 AQMEAVLRENARLQRDNERLQRELES-SAEKAGRIEKLESEIQRLSEAHESLTRASSKREALEKtmrnkmdsEMRRLQDF 390
Cdd:COG1196   239 AELEELEAELEELEAELEELEAELAElEAELEELRLELEELELELEEAQAEEYELLAELARLEQ--------DIARLEER 310

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1394533522 391 NRDLRERLESANRRLASKTQEAQAGSQDMVAKLLAQSYEQQQEQEKLEREMALLRGAIEDQRRRAELLEQALGNAQGRAA 470
Cdd:COG1196   311 RRELEERLEELEEELAELEEELEELEEELEELEEELEEAEEELEEAEAELAEAEEALLEAEAELAEAEEELEELAEELLE 390

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1394533522 471 RAEEELRKKQAYVEKVERLQQALGQLQAACEKREQLELRLRTRLEQELKALRAQQRQAGAPGGSSGSGGSPELSALRLSE 550
Cdd:COG1196   391 ALRAAAELAAQLEELEEAEEALLERLERLEEELEELEEALAELEEEEEEEEEALEEAAEEEAELEEEEEALLELLAELLE 470

                         250       260       270
                  ....*....|....*....|....*....|.
gi 1394533522 551 QLREKEEQILALEADMTKWEQKYLEERAMRQ 581
Cdd:COG1196   471 EAALLEAALAELLEELAEAAARLLLLLEAEA 501
Smc COG1196
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ...
 309-558 6.53e-12

Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 440809 [Multi-domain]  Cd Length: 983  Bit Score: 69.20  E-value: 6.53e-12
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1394533522 309 AHLAQMEAVLREN-ARLQRDNERLQRELESSAEKAGRIEKLESEIQRLSEAHESLTRASSKREALEKTMRNKMDSEMRRL 387
Cdd:COG1196   260 AELAELEAELEELrLELEELELELEEAQAEEYELLAELARLEQDIARLEERRRELEERLEELEEELAELEEELEELEEEL 339

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1394533522 388 QDfnrdLRERLESANRRLASKTQEAQAGSQDMVAKLLAQSYEQQQEQEKLEREMALLRGAIEDQRRRAELlEQALGNAQG 467
Cdd:COG1196   340 EE----LEEELEEAEEELEEAEAELAEAEEALLEAEAELAEAEEELEELAEELLEALRAAAELAAQLEEL-EEAEEALLE 414

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1394533522 468 RAARAEEELRKKQAYVEKVERLQQALGQLQAACEKREQLELRLRTRLEQELKALRAQQRQAGAPGGSSGSGGSPELSALR 547
Cdd:COG1196   415 RLERLEEELEELEEALAELEEEEEEEEEALEEAAEEEAELEEEEEALLELLAELLEEAALLEAALAELLEELAEAAARLL 494

                         250
                  ....*....|.
gi 1394533522 548 LSEQLREKEEQ 558
Cdd:COG1196   495 LLLEAEADYEG 505
Smc COG1196
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ...
 309-704 7.08e-11

Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 440809 [Multi-domain]  Cd Length: 983  Bit Score: 66.11  E-value: 7.08e-11
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1394533522 309 AHLAQMEAVLRE-NARLqrdnERLQRElessAEKAGRIEKLESEIQ---------RLSEAHESLTRASSKREALEKTmRN 378
Cdd:COG1196   186 ENLERLEDILGElERQL----EPLERQ----AEKAERYRELKEELKeleaellllKLRELEAELEELEAELEELEAE-LE 256

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1394533522 379 KMDSEMRRLQDFNRDLRERLESANRRLASKTQEAQAGSQDmVAKLLAQSYEQQQEQEKLEREMALLRGAIEDQRRRAELL 458
Cdd:COG1196   257 ELEAELAELEAELEELRLELEELELELEEAQAEEYELLAE-LARLEQDIARLEERRRELEERLEELEEELAELEEELEEL 335

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1394533522 459 EQALGNAQGRAARAEEELRKKQayvekvERLQQALGQLQAACEKREQLELRLRTRLEQELKALRAQQRQAGAPGGSSGSG 538
Cdd:COG1196   336 EEELEELEEELEEAEEELEEAE------AELAEAEEALLEAEAELAEAEEELEELAEELLEALRAAAELAAQLEELEEAE 409

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1394533522 539 GSPELSALRLSEQLREKEEQILALEADMTKWEQKYLEERAMRQFAMDAAATAAAQRDTTLIRHSPQPSPSSSFNEGLLtg 618
Cdd:COG1196   410 EALLERLERLEEELEELEEALAELEEEEEEEEEALEEAAEEEAELEEEEEALLELLAELLEEAALLEAALAELLEELA-- 487

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1394533522 619 ghRHQEMESRLKVLHAQILEKDAVIKVLQQRSRRDPGKAIQGSLRPAKSVPSVFAAAAAGTQGWQGLSSSERQTADAPAR 698
Cdd:COG1196   488 --EAAARLLLLLEAEADYEGFLEGVKAALLLAGLRGLAGAVAVLIGVEAAYEAALEAALAAALQNIVVEDDEVAAAAIEY 565


                  ....*.
gi 1394533522 699 LTTDRA 704
Cdd:COG1196   566 LKAAKA 571
SMC_prok_A TIGR02169
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of ...
 312-578 1.01e-08

chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. It is found in a single copy and is homodimeric in prokaryotes, but six paralogs (excluded from this family) are found in eukarotes, where SMC proteins are heterodimeric. This family represents the SMC protein of archaea and a few bacteria (Aquifex, Synechocystis, etc); the SMC of other bacteria is described by TIGR02168. The N- and C-terminal domains of this protein are well conserved, but the central hinge region is skewed in composition and highly divergent. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274009 [Multi-domain]  Cd Length: 1164  Bit Score: 58.93  E-value: 1.01e-08
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1394533522  312 AQMEAVLRENARLQRDNERLQRELESSAEK----AGRIEKLESEIQRLSEAHESLTRASSK-REALEKTMRN-------K 379
Cdd:TIGR02169  716 RKIGEIEKEIEQLEQEEEKLKERLEELEEDlsslEQEIENVKSELKELEARIEELEEDLHKlEEALNDLEARlshsripE 795

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1394533522  380 MDSEMRRLQDFNRDLRERLESANRRLASKTQEAQAgSQDMVAKLLAQSYEQQQEQEKLEREMALLRGAIEDQRRRAELLE 459
Cdd:TIGR02169  796 IQAELSKLEEEVSRIEARLREIEQKLNRLTLEKEY-LEKEIQELQEQRIDLKEQIKSIEKEIENLNGKKEELEEELEELE 874

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1394533522  460 QALGNAQGRAARAEEELRKKQAyveKVERLQQALGQLQAACEKREQLELRLRTRLEqelkALRAQQRQAGAPGGSSGSGG 539
Cdd:TIGR02169  875 AALRDLESRLGDLKKERDELEA---QLRELERKIEELEAQIEKKRKRLSELKAKLE----ALEEELSEIEDPKGEDEEIP 947

                          250       260       270
                   ....*....|....*....|....*....|....*....
gi 1394533522  540 SPELSALRLSEQLREKEEQILALEADMTKWEQKYLEERA 578
Cdd:TIGR02169  948 EEELSLEDVQAELQRVEEEIRALEPVNMLAIQEYEEVLK 986
SMC_prok_B TIGR02168
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...
 312-572 2.67e-08

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274008 [Multi-domain]  Cd Length: 1179  Bit Score: 57.76  E-value: 2.67e-08
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1394533522  312 AQMEAVLRENARLQRDNERLQRELESSAEKAGRIEKLESEIQR-LSEAHESLTRASSKREALEKTMRNkMDSEMRRLQDF 390
Cdd:TIGR02168  684 EKIEELEEKIAELEKALAELRKELEELEEELEQLRKELEELSRqISALRKDLARLEAEVEQLEERIAQ-LSKELTELEAE 762

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1394533522  391 NRDLRERLESANRRLASKTQEAQAGSQDmVAKLLAQSYEQQQEQEKLEREMALLRGAIEDQRRRAELLEQALGNAQGRAA 470
Cdd:TIGR02168  763 IEELEERLEEAEEELAEAEAEIEELEAQ-IEQLKEELKALREALDELRAELTLLNEEAANLRERLESLERRIAATERRLE 841

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1394533522  471 RAEEELRKKQayvEKVERLQQALGQLQAACEK-REQLE--LRLRTRLEQELKALRAQQRQagapggSSGSGGSPELSALR 547
Cdd:TIGR02168  842 DLEEQIEELS---EDIESLAAEIEELEELIEElESELEalLNERASLEEALALLRSELEE------LSEELRELESKRSE 912

                          250       260
                   ....*....|....*....|....*
gi 1394533522  548 LSEQLREKEEQILALEADMTKWEQK 572
Cdd:TIGR02168  913 LRRELEELREKLAQLELRLEGLEVR 937
COG4913 COG4913
Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];
344-564 8.36e-08

Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];


Pssm-ID: 443941 [Multi-domain]  Cd Length: 1089  Bit Score: 56.08  E-value: 8.36e-08
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1394533522  344 RIEKLESEIQRLSEAHESLTRASSKREALektmrnkmdsemrrlqdfnrdlrERLESANRRLASKTQEAQAgSQDMVAKL 423
Cdd:COG4913    226 AADALVEHFDDLERAHEALEDAREQIELL-----------------------EPIRELAERYAAARERLAE-LEYLRAAL 281

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1394533522  424 laqsyeqqqEQEKLEREMALLRGAIEDQRRRAELLEQALGNAQGRAARAEEELRK-KQAY----VEKVERLQQALGQLQA 498
Cdd:COG4913    282 ---------RLWFAQRRLELLEAELEELRAELARLEAELERLEARLDALREELDElEAQIrgngGDRLEQLEREIERLER 352

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1394533522  499 ACEKREQLELRLRTRL----------EQELKALRAQQRQAGAPGGSSGSGGSPELSALR-----LSEQLREKEEQILALE 563
Cdd:COG4913    353 ELEERERRRARLEALLaalglplpasAEEFAALRAEAAALLEALEEELEALEEALAEAEaalrdLRRELRELEAEIASLE 432


                   .
gi 1394533522  564 A 564
Cdd:COG4913    433 R 433
SMC_prok_A TIGR02169
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of ...
 320-575 1.39e-07

chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. It is found in a single copy and is homodimeric in prokaryotes, but six paralogs (excluded from this family) are found in eukarotes, where SMC proteins are heterodimeric. This family represents the SMC protein of archaea and a few bacteria (Aquifex, Synechocystis, etc); the SMC of other bacteria is described by TIGR02168. The N- and C-terminal domains of this protein are well conserved, but the central hinge region is skewed in composition and highly divergent. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274009 [Multi-domain]  Cd Length: 1164  Bit Score: 55.46  E-value: 1.39e-07
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1394533522  320 ENARLQRDNERLQRELESSAEKAGRIEKLESEI-QRLSEAHESLTRASSKREALEKTmRNKMDSEMRRLQDFNRDLRERL 398
Cdd:TIGR02169  675 ELQRLRERLEGLKRELSSLQSELRRIENRLDELsQELSDASRKIGEIEKEIEQLEQE-EEKLKERLEELEEDLSSLEQEI 753

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1394533522  399 ESANRRLASKTQEAQAGSQDMVAKLLAQSYEQQQEQEKLEREMALLRGAIEDQRRRAEL----LEQALGNAQGRAARAEE 474
Cdd:TIGR02169  754 ENVKSELKELEARIEELEEDLHKLEEALNDLEARLSHSRIPEIQAELSKLEEEVSRIEArlreIEQKLNRLTLEKEYLEK 833

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1394533522  475 ELRKKQAYVEKVERlqqalgQLQAACEKREQLELRLRtRLEQELKALRAQQRQagapggssgsggspelsalrLSEQLRE 554
Cdd:TIGR02169  834 EIQELQEQRIDLKE------QIKSIEKEIENLNGKKE-ELEEELEELEAALRD--------------------LESRLGD 886

                          250       260
                   ....*....|....*....|.
gi 1394533522  555 KEEQILALEADMTKWEQKYLE 575
Cdd:TIGR02169  887 LKKERDELEAQLRELERKIEE 907
EnvC COG4942
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, ...
 307-527 3.80e-07

Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 443969 [Multi-domain]  Cd Length: 377  Bit Score: 53.23  E-value: 3.80e-07
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1394533522 307 GSAHLAQMEAVLRENARLQRDNERLQRELESSAEKAGRIEKLESEIQRLSEAhesLTRASSKREALEKTMrNKMDSEMRR 386
Cdd:COG4942    12 ALAAAAQADAAAEAEAELEQLQQEIAELEKELAALKKEEKALLKQLAALERR---IAALARRIRALEQEL-AALEAELAE 87

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1394533522 387 LQDFNRDLRERLESANRRLASKTQEAQAGSQDMVAKLLAqsyeQQQEQEKLEREMALLRGAIEDQRRRAELLEQALGNAQ 466
Cdd:COG4942    88 LEKEIAELRAELEAQKEELAELLRALYRLGRQPPLALLL----SPEDFLDAVRRLQYLKYLAPARREQAEELRADLAELA 163

                         170       180       190       200       210       220
                  ....*....|....*....|....*....|....*....|....*....|....*....|.
gi 1394533522 467 GRAARAEEELRKKQAYVEKVERLQQALGQLQAaceKREQLELRLRTRLEQELKALRAQQRQ 527
Cdd:COG4942   164 ALRAELEAERAELEALLAELEEERAALEALKA---ERQKLLARLEKELAELAAELAELQQE 221
SMC_prok_A TIGR02169
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of ...
 309-573 7.62e-06

chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. It is found in a single copy and is homodimeric in prokaryotes, but six paralogs (excluded from this family) are found in eukarotes, where SMC proteins are heterodimeric. This family represents the SMC protein of archaea and a few bacteria (Aquifex, Synechocystis, etc); the SMC of other bacteria is described by TIGR02168. The N- and C-terminal domains of this protein are well conserved, but the central hinge region is skewed in composition and highly divergent. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274009 [Multi-domain]  Cd Length: 1164  Bit Score: 49.68  E-value: 7.62e-06
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1394533522  309 AHLAQMEAVLRENARLQRDNERLQRELESSAEKAGRIEKLESEI----------------QRLSEAHESLTRASSKREAL 372
Cdd:TIGR02169  234 ALERQKEAIERQLASLEEELEKLTEEISELEKRLEEIEQLLEELnkkikdlgeeeqlrvkEKIGELEAEIASLERSIAEK 313

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1394533522  373 EKTMRN------KMDSEMRRLQDFNRDLRERLESANRRLASKTQEAQAGSQDM-------------VAKLLAQSYEQQQE 433
Cdd:TIGR02169  314 ERELEDaeerlaKLEAEIDKLLAEIEELEREIEEERKRRDKLTEEYAELKEELedlraeleevdkeFAETRDELKDYREK 393

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1394533522  434 QEKLEREMALLRGAIEDQRRRAELLEQALGNAQGRAARAEEELRKKQAYVE----KVERLQQALGQLQAACEKREQLELR 509
Cdd:TIGR02169  394 LEKLKREINELKRELDRLQEELQRLSEELADLNAAIAGIEAKINELEEEKEdkalEIKKQEWKLEQLAADLSKYEQELYD 473

                          250       260       270       280       290       300
                   ....*....|....*....|....*....|....*....|....*....|....*....|....
gi 1394533522  510 LRTRLEQELKALRAQQRQAGAPGGSSGSGGSPELSALRLSEQLREKEEQILALEADMTKWEQKY 573
Cdd:TIGR02169  474 LKEEYDRVEKELSKLQRELAEAEAQARASEERVRGGRAVEEVLKASIQGVHGTVAQLGSVGERY 537
COG4913 COG4913
Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];
344-527 1.45e-05

Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];


Pssm-ID: 443941 [Multi-domain]  Cd Length: 1089  Bit Score: 48.76  E-value: 1.45e-05
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1394533522  344 RIEKLESEIQRLSEAHESLTRASSKREALEKTMRNKmDSEMRRLQDFNRDLRErLESANRRLASKTQEAQA--GSQDMVA 421
Cdd:COG4913    611 KLAALEAELAELEEELAEAEERLEALEAELDALQER-REALQRLAEYSWDEID-VASAEREIAELEAELERldASSDDLA 688

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1394533522  422 KLlaqsyeqqqeqeklEREMALLRGAIEDQRRRAELLEQALGNAQGRAARAEEELRKKQAYVEKVERLQQAlgQLQAACE 501
Cdd:COG4913    689 AL--------------EEQLEELEAELEELEEELDELKGEIGRLEKELEQAEEELDELQDRLEAAEDLARL--ELRALLE 752

                          170       180       190
                   ....*....|....*....|....*....|..
gi 1394533522  502 KR------EQLELRLRTRLEQELKALRAQQRQ 527
Cdd:COG4913    753 ERfaaalgDAVERELRENLEERIDALRARLNR 784
PTZ00121 PTZ00121
MAEBL; Provisional
 315-580 1.82e-05

MAEBL; Provisional


Pssm-ID: 173412 [Multi-domain]  Cd Length: 2084  Bit Score: 48.60  E-value: 1.82e-05
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1394533522  315 EAVLRENARLQRDNERLQRELESSAEKAGRIEKLESEIQRLSEAHESLTRASS---KREALEKTMRNKMDSEMRRLQDfN 391
Cdd:PTZ00121  1455 EAKKAEEAKKKAEEAKKADEAKKKAEEAKKADEAKKKAEEAKKKADEAKKAAEakkKADEAKKAEEAKKADEAKKAEE-A 1533

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1394533522  392 RDLRERLESANRRLASKTQEAQAgsqdmVAKLLAQSYEQQQEQEKLEREMALLRGAIEDQ---RRRAELLEQALGNAQGR 468
Cdd:PTZ00121  1534 KKADEAKKAEEKKKADELKKAEE-----LKKAEEKKKAEEAKKAEEDKNMALRKAEEAKKaeeARIEEVMKLYEEEKKMK 1608

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1394533522  469 A--ARAEEELRKKQAYVEKVERLQQALGQLQA--ACEKREQLELR-----LRTRLEQELKALRAQQRQAGAPGGSSGSGG 539
Cdd:PTZ00121  1609 AeeAKKAEEAKIKAEELKKAEEEKKKVEQLKKkeAEEKKKAEELKkaeeeNKIKAAEEAKKAEEDKKKAEEAKKAEEDEK 1688

                          250       260       270       280
                   ....*....|....*....|....*....|....*....|...
gi 1394533522  540 SPELSALRLSEQLREKEEQILALEADMTKWEQ--KYLEERAMR 580
Cdd:PTZ00121  1689 KAAEALKKEAEEAKKAEELKKKEAEEKKKAEElkKAEEENKIK 1731
SMC_prok_B TIGR02168
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...
 322-649 2.35e-05

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274008 [Multi-domain]  Cd Length: 1179  Bit Score: 48.13  E-value: 2.35e-05
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1394533522  322 ARLQRDNERLQRELEssaekagrIEKLESEIQRLSEAHESLTRAsskrealektmRNKMDSEMRRLQDFNRDLRERLESA 401
Cdd:TIGR02168  664 GSAKTNSSILERRRE--------IEELEEKIEELEEKIAELEKA-----------LAELRKELEELEEELEQLRKELEEL 724

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1394533522  402 NRRLASKTQEAQAGSQdmvakllaqsyeqqqEQEKLEREMALLRGAIEDQRRRAELLEQALGNAQGRAARAEEELRKKQA 481
Cdd:TIGR02168  725 SRQISALRKDLARLEA---------------EVEQLEERIAQLSKELTELEAEIEELEERLEEAEEELAEAEAEIEELEA 789

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1394533522  482 yveKVERLQQALGQLqaacekREQLElrlrtRLEQELKALR-AQQRQAGAPGGSSGSGGSPELSALRLSEQLREKEEQIL 560
Cdd:TIGR02168  790 ---QIEQLKEELKAL------REALD-----ELRAELTLLNeEAANLRERLESLERRIAATERRLEDLEEQIEELSEDIE 855

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1394533522  561 ALEADMTkwEQKYLEERAMRQFAMDAAATAAAQRDTTLIRHspqpsPSSSFNEGLLTGGHRHQEMESRLKVLHAQILEKD 640
Cdd:TIGR02168  856 SLAAEIE--ELEELIEELESELEALLNERASLEEALALLRS-----ELEELSEELRELESKRSELRRELEELREKLAQLE 928


                   ....*....
gi 1394533522  641 AVIKVLQQR 649
Cdd:TIGR02168  929 LRLEGLEVR 937
DUF3584 pfam12128
Protein of unknown function (DUF3584); This protein is found in bacteria and eukaryotes. ...
 312-527 5.66e-05

Protein of unknown function (DUF3584); This protein is found in bacteria and eukaryotes. Proteins in this family are typically between 943 to 1234 amino acids in length. This family contains a P-loop motif suggesting it is a nucleotide binding protein. It may be involved in replication.


Pssm-ID: 432349 [Multi-domain]  Cd Length: 1191  Bit Score: 46.76  E-value: 5.66e-05
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1394533522  312 AQMEAVLRENARLQRDNERLQR----ELESSAEKAGRIEKLESEIQRLSEAHESLTRASSKREALEKTMRNKMDSEMRR- 386
Cdd:pfam12128  312 AADAAVAKDRSELEALEDQHGAfldaDIETAAADQEQLPSWQSELENLEERLKALTGKHQDVTAKYNRRRSKIKEQNNRd 391

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1394533522  387 LQDFNRDLRERLESANRRLASKTQEAQAGSQDMVAKLlaqsyeqqqeqekleremallRGAIEDQRRRAELLEQALGNAQ 466
Cdd:pfam12128  392 IAGIKDKLAKIREARDRQLAVAEDDLQALESELREQL---------------------EAGKLEFNEEEYRLKSRLGELK 450

                          170       180       190       200       210       220
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 1394533522  467 GRAARA---EEELRKKQAYVEKVERLQQALGQLQAACEKREQLELRLRTRLEQELKAL-----RAQQRQ 527
Cdd:pfam12128  451 LRLNQAtatPELLLQLENFDERIERAREEQEAANAEVERLQSELRQARKRRDQASEALrqasrRLEERQ 519
SMC_prok_B TIGR02168
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...
 309-652 5.73e-05

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274008 [Multi-domain]  Cd Length: 1179  Bit Score: 46.97  E-value: 5.73e-05
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1394533522  309 AHLAQMEAVLREnarLQRDNERLQRELESsAEKAGRIEKLESEIQ------RLSEAHESLTRASSKREALEkTMRNKMDS 382
Cdd:TIGR02168  186 ENLDRLEDILNE---LERQLKSLERQAEK-AERYKELKAELRELElallvlRLEELREELEELQEELKEAE-EELEELTA 260

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1394533522  383 EMRRLQDfnrdLRERLESANRRLASKTQEAQAGSQDMVAKLlaqsyeqqqeqekleremALLRGAIEDQRRRAELLEQal 462
Cdd:TIGR02168  261 ELQELEE----KLEELRLEVSELEEEIEELQKELYALANEI------------------SRLEQQKQILRERLANLER-- 316

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1394533522  463 gNAQGRAARAEEELRKKQAYVEKVERLQQALGQLQAACEkREQLELRLRTRLEQELKALRAQQRQAGAPGGSSGSGGSPE 542
Cdd:TIGR02168  317 -QLEELEAQLEELESKLDELAEELAELEEKLEELKEELE-SLEAELEELEAELEELESRLEELEEQLETLRSKVAQLELQ 394

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1394533522  543 LSALRlsEQLREKEEQILALEADMTKWEQKYLEERamRQFAMDAAATAAAQRDTTLIRHSPQPSPSSSFNEGLLTGGHRH 622
Cdd:TIGR02168  395 IASLN--NEIERLEARLERLEDRRERLQQEIEELL--KKLEEAELKELQAELEELEEELEELQEELERLEEALEELREEL 470

                          330       340       350
                   ....*....|....*....|....*....|
gi 1394533522  623 QEMESRLKVLHAQILEKDAVIKVLQQRSRR 652
Cdd:TIGR02168  471 EEAEQALDAAERELAQLQARLDSLERLQEN 500
PTZ00121 PTZ00121
MAEBL; Provisional
 309-576 1.30e-04

MAEBL; Provisional


Pssm-ID: 173412 [Multi-domain]  Cd Length: 2084  Bit Score: 45.90  E-value: 1.30e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1394533522  309 AHLAQMEAVLRENARLQRDNERLQRELESSAEKAGRIEKL-ESEIQRLSEahesltrASSKREALEKTMRNKMDSEMRRL 387
Cdd:PTZ00121  1064 AHVGQDEGLKPSYKDFDFDAKEDNRADEATEEAFGKAEEAkKTETGKAEE-------ARKAEEAKKKAEDARKAEEARKA 1136

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1394533522  388 QDFNRDLRERLESANRRLASKTQEAQAGSQDMVAKLLAQSYEQQQEQEKLEREMALLRGAieDQRRRAELLEQALGNAQG 467
Cdd:PTZ00121  1137 EDARKAEEARKAEDAKRVEIARKAEDARKAEEARKAEDAKKAEAARKAEEVRKAEELRKA--EDARKAEAARKAEEERKA 1214

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1394533522  468 RAARAEEELRKKQAyVEKVERLQQALGQLQAACEKREQLELRlrtRLEQELKALRAQQRQAGAPGGSSGSGGSPELSALR 547
Cdd:PTZ00121  1215 EEARKAEDAKKAEA-VKKAEEAKKDAEEAKKAEEERNNEEIR---KFEEARMAHFARRQAAIKAEEARKADELKKAEEKK 1290

                          250       260
                   ....*....|....*....|....*....
gi 1394533522  548 LSEQLREKEEQILALEADMTKWEQKYLEE 576
Cdd:PTZ00121  1291 KADEAKKAEEKKKADEAKKKAEEAKKADE 1319
Smc COG1196
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ...
 441-572 1.64e-04

Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 440809 [Multi-domain]  Cd Length: 983  Bit Score: 45.31  E-value: 1.64e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1394533522 441 MALLRGAIEDQRRRAELLEQALGNAQG---RAARAEEELRKKQAYVEKVERLQQALGQLQAACEKREQLELRLRTRLEQE 517
Cdd:COG1196   634 AALRRAVTLAGRLREVTLEGEGGSAGGsltGGSRRELLAALLEAEAELEELAERLAEEELELEEALLAEEEEERELAEAE 713

                          90       100       110       120       130
                  ....*....|....*....|....*....|....*....|....*....|....*
gi 1394533522 518 LKALRAQQRQAGAPGGSSGSGGSPELSALRLSEQLREKEEQILALEADMTKWEQK 572
Cdd:COG1196   714 EERLEEELEEEALEEQLEAEREELLEELLEEEELLEEEALEELPEPPDLEELERE 768
EnvC COG4942
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, ...
 320-527 1.79e-04

Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 443969 [Multi-domain]  Cd Length: 377  Bit Score: 44.75  E-value: 1.79e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1394533522 320 ENARLQRDNERLQRELessAEKAGRIEKLESEIQRLSEAHESLTRASSKREALEKTMR---NKMDSEMRRLQDFNRDLRE 396
Cdd:COG4942    21 AAAEAEAELEQLQQEI---AELEKELAALKKEEKALLKQLAALERRIAALARRIRALEqelAALEAELAELEKEIAELRA 97

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1394533522 397 RLESANRRLASKTQEAQAGSQDMVAKLLAQSYEQQQEQEKlereMALLRGAIEDQRRRAELLEQALGNAQGRAARAEEEL 476
Cdd:COG4942    98 ELEAQKEELAELLRALYRLGRQPPLALLLSPEDFLDAVRR----LQYLKYLAPARREQAEELRADLAELAALRAELEAER 173

                         170       180       190       200       210       220
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 1394533522 477 RKKQAYVEKVERLQQALGQLQAACEK------------REQLE--LRLRTRLEQELKALRAQQRQ 527
Cdd:COG4942   174 AELEALLAELEEERAALEALKAERQKllarlekelaelAAELAelQQEAEELEALIARLEAEAAA 238
YhaN COG4717
Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown];
311-483 2.52e-04

Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown];


Pssm-ID: 443752 [Multi-domain]  Cd Length: 641  Bit Score: 44.37  E-value: 2.52e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1394533522 311 LAQMEAVLRENARLQRDNERLQRELESSAEKAGRIEKLESEIQRLSEAHESLTRASSKREALE--KTMRNKMDSEMRRLQ 388
Cdd:COG4717    70 LKELKELEEELKEAEEKEEEYAELQEELEELEEELEELEAELEELREELEKLEKLLQLLPLYQelEALEAELAELPERLE 149

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1394533522 389 DFN------RDLRERLESANRRLASKTQEAQAGSQDMVAKLLAQSYEQQQEQEKLEREMALLRGAIEDQRRRAELLEQAL 462
Cdd:COG4717   150 ELEerleelRELEEELEELEAELAELQEELEELLEQLSLATEEELQDLAEELEELQQRLAELEEELEEAQEELEELEEEL 229

                         170       180
                  ....*....|....*....|.
gi 1394533522 463 GNAQGRAARAEEELRKKQAYV 483
Cdd:COG4717   230 EQLENELEAAALEERLKEARL 250
COG4913 COG4913
Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];
311-481 3.59e-04

Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];


Pssm-ID: 443941 [Multi-domain]  Cd Length: 1089  Bit Score: 44.14  E-value: 3.59e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1394533522  311 LAQMEAVLRENARLQRDNERLQRELESSAEKAGRIEK----------LESEIQRLSEAHESLTRASSKREALEKTmRNKM 380
Cdd:COG4913    619 LAELEEELAEAEERLEALEAELDALQERREALQRLAEyswdeidvasAEREIAELEAELERLDASSDDLAALEEQ-LEEL 697

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1394533522  381 DSEMRRLQDFNRDLRERLESANRRLASKTQEAQAgsqdmvAKLLAQSYEQQQEQEKLEREMALLRGAIEDQRRR--AELL 458
Cdd:COG4913    698 EAELEELEEELDELKGEIGRLEKELEQAEEELDE------LQDRLEAAEDLARLELRALLEERFAAALGDAVERelRENL 771

                          170       180
                   ....*....|....*....|...
gi 1394533522  459 EQALGNAQGRAARAEEELRKKQA 481
Cdd:COG4913    772 EERIDALRARLNRAEEELERAMR 794
YhaN COG4717
Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown];
309-499 4.01e-04

Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown];


Pssm-ID: 443752 [Multi-domain]  Cd Length: 641  Bit Score: 43.99  E-value: 4.01e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1394533522 309 AHLAQMEAVLRENARLQRDNERLQRELESSAEKAGRIEKLESEIQRLSEAHESLTRASSKREALEKTmRNKMDSEMRRLQ 388
Cdd:COG4717    71 KELKELEEELKEAEEKEEEYAELQEELEELEEELEELEAELEELREELEKLEKLLQLLPLYQELEAL-EAELAELPERLE 149

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1394533522 389 DFNRDLRErLESANRRLASKTQEAQAGSQDMVAKLLAQSYEQQQEQEKLEREMALLRGAIEDQRRRAELLEQALGNAQGR 468
Cdd:COG4717   150 ELEERLEE-LRELEEELEELEAELAELQEELEELLEQLSLATEEELQDLAEELEELQQRLAELEEELEEAQEELEELEEE 228

                         170       180       190
                  ....*....|....*....|....*....|.
gi 1394533522 469 AARAEEELRKKQAYvekvERLQQALGQLQAA 499
Cdd:COG4717   229 LEQLENELEAAALE----ERLKEARLLLLIA 255
COG4913 COG4913
Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];
450-577 4.87e-04

Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];


Pssm-ID: 443941 [Multi-domain]  Cd Length: 1089  Bit Score: 43.75  E-value: 4.87e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1394533522  450 DQRRRAELLEQALGNAQGRAARAEEELRKKQAYVEKVERLQQALGQLQ----------AACEKREQLELRLR-------- 511
Cdd:COG4913    607 DNRAKLAALEAELAELEEELAEAEERLEALEAELDALQERREALQRLAeyswdeidvaSAEREIAELEAELErldassdd 686

                           90       100       110       120       130       140
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 1394533522  512 -TRLEQELKALRAQQRQAGAPGGSSGSGGSPELSAL-RLSEQLREKEEQILALEADMTKWEQKYLEER 577
Cdd:COG4913    687 lAALEEQLEELEAELEELEEELDELKGEIGRLEKELeQAEEELDELQDRLEAAEDLARLELRALLEER 754
SMC_prok_B TIGR02168
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...
 444-652 1.12e-03

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274008 [Multi-domain]  Cd Length: 1179  Bit Score: 42.74  E-value: 1.12e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1394533522  444 LRGAIEDQRRRAELLEQALGNAQGRAARAEEELRKKQAYVEKVERLQQALGQLQAACEKREQLELRLRTRLEQELKALrA 523
Cdd:TIGR02168  682 LEEKIEELEEKIAELEKALAELRKELEELEEELEQLRKELEELSRQISALRKDLARLEAEVEQLEERIAQLSKELTEL-E 760

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1394533522  524 QQRQAGAPGGSSGSGGSPELSALR--LSEQLREKEEQILALEADMTKWEQKYLEERAMRQFAMDAAATAAAQRDTTLIRH 601
Cdd:TIGR02168  761 AEIEELEERLEEAEEELAEAEAEIeeLEAQIEQLKEELKALREALDELRAELTLLNEEAANLRERLESLERRIAATERRL 840

                          170       180       190       200       210
                   ....*....|....*....|....*....|....*....|....*....|.
gi 1394533522  602 SPQPSPSSSFNEGLLTGGHRHQEMESRLKVLHAQILEKDAVIKVLQQRSRR 652
Cdd:TIGR02168  841 EDLEEQIEELSEDIESLAAEIEELEELIEELESELEALLNERASLEEALAL 891
HlpA COG2825
Periplasmic chaperone for outer membrane proteins, Skp family [Cell wall/membrane/envelope ...
 311-412 1.93e-03

Periplasmic chaperone for outer membrane proteins, Skp family [Cell wall/membrane/envelope biogenesis, Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 442073 [Multi-domain]  Cd Length: 171  Bit Score: 39.82  E-value: 1.93e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1394533522 311 LAQMEAVLRENARLQRDNERLQRELESsaeKAGRIEKLESEIQRlseahESLTRASSKREALEKTMRNKMDSEMRRLQDF 390
Cdd:COG2825    35 LQESPEGKAAQKKLEKEFKKRQAELQK---LEKELQALQEKLQK-----EAATLSEEERQKKERELQKKQQELQRKQQEA 106

                          90       100
                  ....*....|....*....|..
gi 1394533522 391 NRDLRERLESANRRLASKTQEA 412
Cdd:COG2825   107 QQDLQKRQQELLQPILEKIQKA 128
PTZ00121 PTZ00121
MAEBL; Provisional
 320-557 2.29e-03

MAEBL; Provisional


Pssm-ID: 173412 [Multi-domain]  Cd Length: 2084  Bit Score: 41.67  E-value: 2.29e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1394533522  320 ENARLQRDNERLqrELESSAEKAGRIE--KLESEIQRLSEAH--ESLTRASSKREALE--KTMRNKMDSEMRRLQDFNRD 393
Cdd:PTZ00121  1143 EEARKAEDAKRV--EIARKAEDARKAEeaRKAEDAKKAEAARkaEEVRKAEELRKAEDarKAEAARKAEEERKAEEARKA 1220

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1394533522  394 LRERLESANRRLASKTQEAQAGSQdmvAKLLAQSYEQQQEQEKLEREMALLRGAIE-DQRRRAELLEQALGNAQGRAARA 472
Cdd:PTZ00121  1221 EDAKKAEAVKKAEEAKKDAEEAKK---AEEERNNEEIRKFEEARMAHFARRQAAIKaEEARKADELKKAEEKKKADEAKK 1297

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1394533522  473 EEELRKKQAYVEKVERLQQALGQLQAACEKREQLELRLRTRLEQELKALRAQQRQAGAPGGSSGSGGSPELSALRLSEQL 552
Cdd:PTZ00121  1298 AEEKKKADEAKKKAEEAKKADEAKKKAEEAKKKADAAKKKAEEAKKAAEAAKAEAEAAADEAEAAEEKAEAAEKKKEEAK 1377


                   ....*
gi 1394533522  553 REKEE 557
Cdd:PTZ00121  1378 KKADA 1382
DUF5401 pfam17380
Family of unknown function (DUF5401); This is a family of unknown function found in ...
 318-513 2.66e-03

Family of unknown function (DUF5401); This is a family of unknown function found in Chromadorea.


Pssm-ID: 375164 [Multi-domain]  Cd Length: 722  Bit Score: 41.26  E-value: 2.66e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1394533522 318 LRENARL----QRDNERLQRELESsaekAGRIEKLESEIQRlseaheSLTRASSKREALEKTMRNKMDSEMRRLQDFN-R 392
Cdd:pfam17380 377 MRELERLqmerQQKNERVRQELEA----ARKVKILEEERQR------KIQQQKVEMEQIRAEQEEARQREVRRLEEERaR 446

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1394533522 393 DL-RERLESANR-----RLASKTQEAQAGSQDMVAKLLAQSYEQQQEQEKLEREMALLRGAIEDQRRRAELLEQALGNAQ 466
Cdd:pfam17380 447 EMeRVRLEEQERqqqveRLRQQEEERKRKKLELEKEKRDRKRAEEQRRKILEKELEERKQAMIEEERKRKLLEKEMEERQ 526

                         170       180       190       200       210
                  ....*....|....*....|....*....|....*....|....*....|..
gi 1394533522 467 GRAA-----RAEEELRKKQAYVEKVERLQQalgQLQAACEKREQLELRLRTR 513
Cdd:pfam17380 527 KAIYeeerrREAEEERRKQQEMEERRRIQE---QMRKATEERSRLEAMERER 575
OmpH smart00935
Outer membrane protein (OmpH-like); This family includes outer membrane proteins such as OmpH ...
 311-412 2.98e-03

Outer membrane protein (OmpH-like); This family includes outer membrane proteins such as OmpH among others. Skp (OmpH) has been characterized as a molecular chaperone that interacts with unfolded proteins as they emerge in the periplasm from the Sec translocation machinery.


Pssm-ID: 214922 [Multi-domain]  Cd Length: 140  Bit Score: 38.72  E-value: 2.98e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1394533522  311 LAQMEAVLRENARLQRDNERLQRELESSAEKagrIEKLESEIQRlseahESLTRASSKREALEKTMRNKMDSEMRRLQDF 390
Cdd:smart00935  10 LQESPAGKAAQKQLEKEFKKRQAELEKLEKE---LQKLKEKLQK-----DAATLSEAAREKKEKELQKKVQEFQRKQQKL 81

                           90       100
                   ....*....|....*....|..
gi 1394533522  391 NRDLRERLESANRRLASKTQEA 412
Cdd:smart00935  82 QQDLQKRQQEELQKILDKINKA 103
SMC_prok_B TIGR02168
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...
 299-521 5.09e-03

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274008 [Multi-domain]  Cd Length: 1179  Bit Score: 40.43  E-value: 5.09e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1394533522  299 AQASSATSGSAHLAQMEAVLRENARLQRDNERLQRELESSAEKAGRIEKLESEIQRLSEAHESLTRASSKREALektmRN 378
Cdd:TIGR02168  794 LKEELKALREALDELRAELTLLNEEAANLRERLESLERRIAATERRLEDLEEQIEELSEDIESLAAEIEELEEL----IE 869

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1394533522  379 KMDSEMRRLQDFNRDLRERLESANRRLASKTQEAQAGSQDMVAkllaqsyeqqqeqekleremalLRGAIEDQRRRAELL 458
Cdd:TIGR02168  870 ELESELEALLNERASLEEALALLRSELEELSEELRELESKRSE----------------------LRRELEELREKLAQL 927

                          170       180       190       200       210       220
                   ....*....|....*....|....*....|....*....|....*....|....*....|....
gi 1394533522  459 EQALGNAQGRAARAEEELRkkqayvEKVERLQQALGQLQAACE-KREQLELRLRtRLEQELKAL 521
Cdd:TIGR02168  928 ELRLEGLEVRIDNLQERLS------EEYSLTLEEAEALENKIEdDEEEARRRLK-RLENKIKEL 984
HOOK pfam05622
HOOK protein coiled-coil region; This family consists of several HOOK1, 2 and 3 proteins from ...
 312-568 5.92e-03

HOOK protein coiled-coil region; This family consists of several HOOK1, 2 and 3 proteins from different eukaryotic organizms. The different members of the human gene family are HOOK1, HOOK2 and HOOK3. Different domains have been identified in the three human HOOK proteins, and it was demonstrated that the highly conserved NH2-domain mediates attachment to microtubules, whereas this central coiled-coil motif mediates homodimerization and the more divergent C-terminal domains are involved in binding to specific organelles (organelle-binding domains). It has been demonstrated that endogenous HOOK3 binds to Golgi membranes, whereas both HOOK1 and HOOK2 are localized to discrete but unidentified cellular structures. In mice the Hook1 gene is predominantly expressed in the testis. Hook1 function is necessary for the correct positioning of microtubular structures within the haploid germ cell. Disruption of Hook1 function in mice causes abnormal sperm head shape and fragile attachment of the flagellum to the sperm head. This entry includes the central coiled-coiled domain and the divergent C-terminal domain.


Pssm-ID: 461694 [Multi-domain]  Cd Length: 528  Bit Score: 40.06  E-value: 5.92e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1394533522 312 AQMEAVLRENARL--QRDNER-LQRELESSAEKAGRIEKLESEIQRLSEAHESLTRASSKREALEKTMRnkmdsemrrLQ 388
Cdd:pfam05622 218 EKLEALQKEKERLiiERDTLReTNEELRCAQLQQAELSQADALLSPSSDPGDNLAAEIMPAEIREKLIR---------LQ 288

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1394533522 389 DFNRDLRERLESANRRLASKTQEAQAGSQDMVAKLLAQSYEQQQEQEKLEREMALLRGAIEDQRRRAE---LLEQALGNA 465
Cdd:pfam05622 289 HENKMLRLGQEGSYRERLTELQQLLEDANRRKNELETQNRLANQRILELQQQVEELQKALQEQGSKAEdssLLKQKLEEH 368

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1394533522 466 QGRAARAEEELRKKQAYVEKVE-----RLQQALGQLQAACEKREQ----LELRLRTRLEQE---LKALRAQQRQagapgg 533
Cdd:pfam05622 369 LEKLHEAQSELQKKKEQIEELEpkqdsNLAQKIDELQEALRKKDEdmkaMEERYKKYVEKAksvIKTLDPKQNP------ 442

                         250       260       270
                  ....*....|....*....|....*....|....*
gi 1394533522 534 ssgsGGSPELSALRlsEQLREKEEQILALEADMTK 568
Cdd:pfam05622 443 ----ASPPEIQALK--NQLLEKDKKIEHLERDFEK 471
PRK02224 PRK02224
DNA double-strand break repair Rad50 ATPase;
311-527 7.68e-03

DNA double-strand break repair Rad50 ATPase;


Pssm-ID: 179385 [Multi-domain]  Cd Length: 880  Bit Score: 39.64  E-value: 7.68e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1394533522 311 LAQMEAVLRENARLQRDNERLQRE---------------LESSAEKAGRIEKLESEIQRLSEAHESLTRASSKREALEKT 375
Cdd:PRK02224  428 EAELEATLRTARERVEEAEALLEAgkcpecgqpvegsphVETIEEDRERVEELEAELEDLEEEVEEVEERLERAEDLVEA 507

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1394533522 376 MRNKMDSEMRR--LQDFNRDLRERLESANRRLASKTQEAQAGSQDMVAKllaqsyeqqqeqeklEREMALLRGAIEDQRR 453
Cdd:PRK02224  508 EDRIERLEERRedLEELIAERRETIEEKRERAEELRERAAELEAEAEEK---------------REAAAEAEEEAEEARE 572

                         170       180       190       200       210       220       230
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 1394533522 454 RAELLEQALGNAQGRAaraeEELRKKQAYVEKVERLQQALGQLQaacEKREQLELRLRTRLEQeLKALRAQQRQ 527
Cdd:PRK02224  573 EVAELNSKLAELKERI----ESLERIRTLLAAIADAEDEIERLR---EKREALAELNDERRER-LAEKRERKRE 638
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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