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Conserved domains on  [gi|1593208012|ref|NP_001356001|]
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serine/arginine repetitive matrix protein 1 isoform 8 [Mus musculus]

Protein Classification

PWI domain-containing protein( domain architecture ID 10478549)

PWI domain-containing protein may function as a splicing factor; similar to Homo sapiens serine/arginine repetitive matrix protein 1 that is involved in numerous pre-mRNA processing events

CATH:  1.20.1390.10
Gene Ontology:  GO:0006397|GO:0003676
PubMed:  10322432|12600940
SCOP:  4000671

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
PWI pfam01480
PWI domain;
46-115 3.74e-38

PWI domain;


:

Pssm-ID: 460224 [Multi-domain]  Cd Length: 71  Bit Score: 136.48  E-value: 3.74e-38
                          10        20        30        40        50        60        70
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1593208012  46 EVIKPWITKRVTEILGFEDDVVIEFIFNQLEVKNPDSKMMQINLTGFLNgKNAREFMGELWPLLLSAQEN 115
Cdd:pfam01480   1 EVLKPWIEKKITEILGFEDDVVVEYVVNLLEEKFPDPKELQIQLTGFLD-KDAAKFVKELWKLLLSAQES 69
PHA03307 super family cl33723
transcriptional regulator ICP4; Provisional
 594-791 5.61e-06

transcriptional regulator ICP4; Provisional


The actual alignment was detected with superfamily member PHA03307:

Pssm-ID: 223039 [Multi-domain]  Cd Length: 1352  Bit Score: 50.55  E-value: 5.61e-06
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1593208012  594 SPSPPPKRRTASPPPPPKRRASPSPPPKRRVSHSPPPKQRSPTVTKRRSPSLSSKHRKGSSPGRSTREARSPQPNkrhSP 673
Cdd:PHA03307   101 AREGSPTPPGPSSPDPPPPTPPPASPPPSPAPDLSEMLRPVGSPGPPPAASPPAAGASPAAVASDAASSRQAALP---LS 177

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1593208012  674 SPRPRAPQTSSPPPVRRGASASPQGRQSPSPSTRPIRRVSRTPEPKKIKKAASPSPQSVRRVSSSRSVSGSPEPAAKKPP 753
Cdd:PHA03307   178 SPEETARAPSSPPAEPPPSTPPAAASPRPPRRSSPISASASSPAPAPGRSAADDAGASSSDSSSSESSGCGWGPENECPL 257

                          170       180       190
                   ....*....|....*....|....*....|....*...
gi 1593208012  754 APPSPVQSQSPSTNWSPAVPAKKAKSPTPSLSPARNSD 791
Cdd:PHA03307   258 PRPAPITLPTRIWEASGWNGPSSRPGPASSSSSPRERS 295
 
Name Accession Description Interval E-value
PWI pfam01480
PWI domain;
46-115 3.74e-38

PWI domain;


Pssm-ID: 460224 [Multi-domain]  Cd Length: 71  Bit Score: 136.48  E-value: 3.74e-38
                          10        20        30        40        50        60        70
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1593208012  46 EVIKPWITKRVTEILGFEDDVVIEFIFNQLEVKNPDSKMMQINLTGFLNgKNAREFMGELWPLLLSAQEN 115
Cdd:pfam01480   1 EVLKPWIEKKITEILGFEDDVVVEYVVNLLEEKFPDPKELQIQLTGFLD-KDAAKFVKELWKLLLSAQES 69
PWI smart00311
PWI, domain in splicing factors;
40-115 1.92e-28

PWI, domain in splicing factors;


Pssm-ID: 214609 [Multi-domain]  Cd Length: 74  Bit Score: 108.97  E-value: 1.92e-28
                           10        20        30        40        50        60        70
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 1593208012   40 MSKVNLEVIKPWITKRVTEILGFEDDVVIEFIFNQLEV-KNPDSKMMQINLTGFLngkNAREFMGELWPLLLSAQEN 115
Cdd:smart00311   1 LSKLKLDEIKPWITKKVIEFLGFEEDTLVEFILSQIRQhKGPQAKLLQINLTGFE---DAEEFVDKLWRLLIFELKN 74
PHA03307 PHA03307
transcriptional regulator ICP4; Provisional
 594-791 5.61e-06

transcriptional regulator ICP4; Provisional


Pssm-ID: 223039 [Multi-domain]  Cd Length: 1352  Bit Score: 50.55  E-value: 5.61e-06
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1593208012  594 SPSPPPKRRTASPPPPPKRRASPSPPPKRRVSHSPPPKQRSPTVTKRRSPSLSSKHRKGSSPGRSTREARSPQPNkrhSP 673
Cdd:PHA03307   101 AREGSPTPPGPSSPDPPPPTPPPASPPPSPAPDLSEMLRPVGSPGPPPAASPPAAGASPAAVASDAASSRQAALP---LS 177

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1593208012  674 SPRPRAPQTSSPPPVRRGASASPQGRQSPSPSTRPIRRVSRTPEPKKIKKAASPSPQSVRRVSSSRSVSGSPEPAAKKPP 753
Cdd:PHA03307   178 SPEETARAPSSPPAEPPPSTPPAAASPRPPRRSSPISASASSPAPAPGRSAADDAGASSSDSSSSESSGCGWGPENECPL 257

                          170       180       190
                   ....*....|....*....|....*....|....*...
gi 1593208012  754 APPSPVQSQSPSTNWSPAVPAKKAKSPTPSLSPARNSD 791
Cdd:PHA03307   258 PRPAPITLPTRIWEASGWNGPSSRPGPASSSSSPRERS 295
Pneumo_att_G pfam05539
Pneumovirinae attachment membrane glycoprotein G;
597-730 3.03e-04

Pneumovirinae attachment membrane glycoprotein G;


Pssm-ID: 114270 [Multi-domain]  Cd Length: 408  Bit Score: 44.27  E-value: 3.03e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1593208012 597 PPPKRRTASPPPPPKRRASPSPPPKRRVSHSPPPKQRSPTVTKRRSPSLSSKHRKGSSPGRSTREARSPQPNKRHSPSPR 676
Cdd:pfam05539 168 PKTAVTTSKTTSWPTEVSHPTYPSQVTPQSQPATQGHQTATANQRLSSTEPVGTQGTTTSSNPEPQTEPPPSQRGPSGSP 247

                          90       100       110       120       130
                  ....*....|....*....|....*....|....*....|....*....|....*..
gi 1593208012 677 PRAPQTSSPPPVRRGAS--ASPQGRQSPSPS-TRPIRRVSRTPEPKKIKKAASPSPQ 730
Cdd:pfam05539 248 QHPPSTTSQDQSTTGDGqeHTQRRKTPPATSnRRSPHSTATPPPTTKRQETGRPTPR 304
 
Name Accession Description Interval E-value
PWI pfam01480
PWI domain;
46-115 3.74e-38

PWI domain;


Pssm-ID: 460224 [Multi-domain]  Cd Length: 71  Bit Score: 136.48  E-value: 3.74e-38
                          10        20        30        40        50        60        70
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1593208012  46 EVIKPWITKRVTEILGFEDDVVIEFIFNQLEVKNPDSKMMQINLTGFLNgKNAREFMGELWPLLLSAQEN 115
Cdd:pfam01480   1 EVLKPWIEKKITEILGFEDDVVVEYVVNLLEEKFPDPKELQIQLTGFLD-KDAAKFVKELWKLLLSAQES 69
PWI smart00311
PWI, domain in splicing factors;
40-115 1.92e-28

PWI, domain in splicing factors;


Pssm-ID: 214609 [Multi-domain]  Cd Length: 74  Bit Score: 108.97  E-value: 1.92e-28
                           10        20        30        40        50        60        70
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 1593208012   40 MSKVNLEVIKPWITKRVTEILGFEDDVVIEFIFNQLEV-KNPDSKMMQINLTGFLngkNAREFMGELWPLLLSAQEN 115
Cdd:smart00311   1 LSKLKLDEIKPWITKKVIEFLGFEEDTLVEFILSQIRQhKGPQAKLLQINLTGFE---DAEEFVDKLWRLLIFELKN 74
PHA03307 PHA03307
transcriptional regulator ICP4; Provisional
 594-791 5.61e-06

transcriptional regulator ICP4; Provisional


Pssm-ID: 223039 [Multi-domain]  Cd Length: 1352  Bit Score: 50.55  E-value: 5.61e-06
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1593208012  594 SPSPPPKRRTASPPPPPKRRASPSPPPKRRVSHSPPPKQRSPTVTKRRSPSLSSKHRKGSSPGRSTREARSPQPNkrhSP 673
Cdd:PHA03307   101 AREGSPTPPGPSSPDPPPPTPPPASPPPSPAPDLSEMLRPVGSPGPPPAASPPAAGASPAAVASDAASSRQAALP---LS 177

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1593208012  674 SPRPRAPQTSSPPPVRRGASASPQGRQSPSPSTRPIRRVSRTPEPKKIKKAASPSPQSVRRVSSSRSVSGSPEPAAKKPP 753
Cdd:PHA03307   178 SPEETARAPSSPPAEPPPSTPPAAASPRPPRRSSPISASASSPAPAPGRSAADDAGASSSDSSSSESSGCGWGPENECPL 257

                          170       180       190
                   ....*....|....*....|....*....|....*...
gi 1593208012  754 APPSPVQSQSPSTNWSPAVPAKKAKSPTPSLSPARNSD 791
Cdd:PHA03307   258 PRPAPITLPTRIWEASGWNGPSSRPGPASSSSSPRERS 295
PHA03247 PHA03247
large tegument protein UL36; Provisional
 594-789 8.81e-06

large tegument protein UL36; Provisional


Pssm-ID: 223021 [Multi-domain]  Cd Length: 3151  Bit Score: 49.94  E-value: 8.81e-06
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1593208012  594 SPSPPPKRRTASPPPPPKRRASPSPPPKRRVShSPPPKQRSPTVTKRRSPSLSSKHRKGSSPGRST-REARSPQPNKRHS 672
Cdd:PHA03247  2753 GPARPARPPTTAGPPAPAPPAAPAAGPPRRLT-RPAVASLSESRESLPSPWDPADPPAAVLAPAAAlPPAASPAGPLPPP 2831

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1593208012  673 PSPRPRAPQTSSPP---------------PVRRGASASPQGRQSPSPSTRPIRRVSRTPEPKKIKKAASPSPQSVRRVSS 737
Cdd:PHA03247  2832 TSAQPTAPPPPPGPpppslplggsvapggDVRRRPPSRSPAAKPAAPARPPVRRLARPAVSRSTESFALPPDQPERPPQP 2911

                          170       180       190       200       210
                   ....*....|....*....|....*....|....*....|....*....|...
gi 1593208012  738 SRSVSGSPEPAAKKPPAPPSPVQSQS-PSTNWSPAVPAKKAKSPTPSLSPARN 789
Cdd:PHA03247  2912 QAPPPPQPQPQPPPPPQPQPPPPPPPrPQPPLAPTTDPAGAGEPSGAVPQPWL 2964
PRK12323 PRK12323
DNA polymerase III subunit gamma/tau;
595-790 6.05e-05

DNA polymerase III subunit gamma/tau;


Pssm-ID: 237057 [Multi-domain]  Cd Length: 700  Bit Score: 46.79  E-value: 6.05e-05
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1593208012 595 PSPPPKRRTASPPPPPKRRASPSPPPKrrVSHSPPPKQRSPTvtkRRSPSLSS--KHRKGSSPGRSTREARSPQPNKRHS 672
Cdd:PRK12323  385 PAPAAAAPAAAAPAPAAPPAAPAAAPA--AAAAARAVAAAPA---RRSPAPEAlaAARQASARGPGGAPAPAPAPAAAPA 459

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1593208012 673 PSPRPRAPQTSSPPPvrrgASASPQGRQSPSPSTRPIRRvSRTPEPKKIKKAASPSPQSVRRVSSSRSVSGSPEPAAKKP 752
Cdd:PRK12323  460 AAARPAAAGPRPVAA----AAAAAPARAAPAAAPAPADD-DPPPWEELPPEFASPAPAQPDAAPAGWVAESIPDPATADP 534

                         170       180       190
                  ....*....|....*....|....*....|....*...
gi 1593208012 753 PAPPSpvqSQSPSTNWSPAVPAKKAKSPTPSLSPARNS 790
Cdd:PRK12323  535 DDAFE---TLAPAPAAAPAPRAAAATEPVVAPRPPRAS 569
PRK07764 PRK07764
DNA polymerase III subunits gamma and tau; Validated
 592-787 6.17e-05

DNA polymerase III subunits gamma and tau; Validated


Pssm-ID: 236090 [Multi-domain]  Cd Length: 824  Bit Score: 46.90  E-value: 6.17e-05
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1593208012 592 RYSPSPPPKRRTASPPPPPKRRASPSPPPKRRVSHSPPPKQRSPTVTKRRSPSLSSKHRKGSSPGRSTREARSPQPNKRH 671
Cdd:PRK07764  585 EAVVGPAPGAAGGEGPPAPASSGPPEEAARPAAPAAPAAPAAPAPAGAAAAPAEASAAPAPGVAAPEHHPKHVAVPDASD 664

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1593208012 672 SPSPRPR----APQTSSPPPVRRGASASPQGRQSPSPSTRPirRVSRTPEPKKIKKAASPSPQSVRRVSSSRSVSGSPEP 747
Cdd:PRK07764  665 GGDGWPAkaggAAPAAPPPAPAPAAPAAPAGAAPAQPAPAP--AATPPAGQADDPAAQPPQAAQGASAPSPAADDPVPLP 742

                         170       180       190       200
                  ....*....|....*....|....*....|....*....|
gi 1593208012 748 AAKKPPAPPSPVQSQSPSTNWSPAVPAKKAKSPTPSLSPA 787
Cdd:PRK07764  743 PEPDDPPDPAGAPAQPPPPPAPAPAAAPAAAPPPSPPSEE 782
PHA03307 PHA03307
transcriptional regulator ICP4; Provisional
 348-697 6.55e-05

transcriptional regulator ICP4; Provisional


Pssm-ID: 223039 [Multi-domain]  Cd Length: 1352  Bit Score: 47.09  E-value: 6.55e-05
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1593208012  348 SPPRKTRRLSPSASPPRRRHRPSSPATPPPktrhSPTPQQSNRTRKSRVSVSPGRTSGKVTKHKGTEKRESPSPAPKPRK 427
Cdd:PHA03307    99 SPAREGSPTPPGPSSPDPPPPTPPPASPPP----SPAPDLSEMLRPVGSPGPPPAASPPAAGASPAAVASDAASSRQAAL 174

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1593208012  428 VELSESEEDKGSKMAAADSVQQRRQYRRQNQQSSSDSGSSSTSEDERPKRSHVKNGEVGRRRRHSPSRSASPSPRKRQKE 507
Cdd:PHA03307   175 PLSSPEETARAPSSPPAEPPPSTPPAAASPRPPRRSSPISASASSPAPAPGRSAADDAGASSSDSSSSESSGCGWGPENE 254

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1593208012  508 TsPRmqmgkrwQSPVTKSSRRRRSPSPPPARRRRSPSPAPPPPPPPPPPRRRRSPTPPPRRRTPSPPPRRRSPSPRRYSP 587
Cdd:PHA03307   255 C-PL-------PRPAPITLPTRIWEASGWNGPSSRPGPASSSSSPRERSPSPSPSSPGSGPAPSSPRASSSSSSSRESSS 326

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1593208012  588 PIQRRYSPSPppkrRTASPPPPPKRRASPSPPPKRRVSHSPPPKQRSPTVTKRRSPSLSskhrKGSSPGRSTREARSPQP 667
Cdd:PHA03307   327 SSTSSSSESS----RGAAVSPGPSPSRSPSPSRPPPPADPSSPRKRPRPSRAPSSPAAS----AGRPTRRRARAAVAGRA 398

                          330       340       350
                   ....*....|....*....|....*....|
gi 1593208012  668 NKRHSPSPRPRAPQTSSPPPVRRGASASPQ 697
Cdd:PHA03307   399 RRRDATGRFPAGRPRPSPLDAGAASGAFYA 428
PHA03307 PHA03307
transcriptional regulator ICP4; Provisional
 598-795 7.13e-05

transcriptional regulator ICP4; Provisional


Pssm-ID: 223039 [Multi-domain]  Cd Length: 1352  Bit Score: 46.70  E-value: 7.13e-05
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1593208012  598 PPKRRTASPPPPPKRRASPSPPPKRRVSHSPPPKQRSPTVTKRRSPSLSSKHRKGSSPGRSTREARSPQP---------- 667
Cdd:PHA03307   108 PPGPSSPDPPPPTPPPASPPPSPAPDLSEMLRPVGSPGPPPAASPPAAGASPAAVASDAASSRQAALPLSspeetaraps 187

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1593208012  668 ---------NKRHSPSPRPRAPQTSSPPPVRRGASASPQGRQSPSPSTRPIRRVSRTPEPKKIKKAASPSPQSVRRVSSS 738
Cdd:PHA03307   188 sppaepppsTPPAAASPRPPRRSSPISASASSPAPAPGRSAADDAGASSSDSSSSESSGCGWGPENECPLPRPAPITLPT 267

                          170       180       190       200       210
                   ....*....|....*....|....*....|....*....|....*....|....*...
gi 1593208012  739 RSVSGSPEPAAKKPPAPPSPVQS-QSPSTNWSPAVPAKKAKSPTPSLSPARNSDQEGG 795
Cdd:PHA03307   268 RIWEASGWNGPSSRPGPASSSSSpRERSPSPSPSSPGSGPAPSSPRASSSSSSSRESS 325
Pneumo_att_G pfam05539
Pneumovirinae attachment membrane glycoprotein G;
597-730 3.03e-04

Pneumovirinae attachment membrane glycoprotein G;


Pssm-ID: 114270 [Multi-domain]  Cd Length: 408  Bit Score: 44.27  E-value: 3.03e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1593208012 597 PPPKRRTASPPPPPKRRASPSPPPKRRVSHSPPPKQRSPTVTKRRSPSLSSKHRKGSSPGRSTREARSPQPNKRHSPSPR 676
Cdd:pfam05539 168 PKTAVTTSKTTSWPTEVSHPTYPSQVTPQSQPATQGHQTATANQRLSSTEPVGTQGTTTSSNPEPQTEPPPSQRGPSGSP 247

                          90       100       110       120       130
                  ....*....|....*....|....*....|....*....|....*....|....*..
gi 1593208012 677 PRAPQTSSPPPVRRGAS--ASPQGRQSPSPS-TRPIRRVSRTPEPKKIKKAASPSPQ 730
Cdd:pfam05539 248 QHPPSTTSQDQSTTGDGqeHTQRRKTPPATSnRRSPHSTATPPPTTKRQETGRPTPR 304
PRK14951 PRK14951
DNA polymerase III subunits gamma and tau; Provisional
 592-718 4.82e-04

DNA polymerase III subunits gamma and tau; Provisional


Pssm-ID: 237865 [Multi-domain]  Cd Length: 618  Bit Score: 43.93  E-value: 4.82e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1593208012 592 RYSPSPPPKRRTASPPPPPKRRASPSPPPKR---RVSHSPPPKQRSPTVTkrrSPSlsskhrkGSSPGRSTREARSPQPN 668
Cdd:PRK14951  367 AAAAEAAAPAEKKTPARPEAAAPAAAPVAQAaaaPAPAAAPAAAASAPAA---PPA-------AAPPAPVAAPAAAAPAA 436

                          90       100       110       120       130
                  ....*....|....*....|....*....|....*....|....*....|
gi 1593208012 669 KRHsPSPRPRAPQTSSPPPVRRGASASPQgRQSPSPSTRPIRRVSRTPEP 718
Cdd:PRK14951  437 APA-AAPAAVALAPAPPAQAAPETVAIPV-RVAPEPAVASAAPAPAAAPA 484
PRK14951 PRK14951
DNA polymerase III subunits gamma and tau; Provisional
 595-707 9.48e-04

DNA polymerase III subunits gamma and tau; Provisional


Pssm-ID: 237865 [Multi-domain]  Cd Length: 618  Bit Score: 42.78  E-value: 9.48e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1593208012 595 PSPPPKRRTASPPPPPKRRASPSPPPKRRVshsPPPKQRSPTVTKrrspslsskhrkgSSPGRSTREARSPQPNKRHSPS 674
Cdd:PRK14951  393 PVAQAAAAPAPAAAPAAAASAPAAPPAAAP---PAPVAAPAAAAP-------------AAAPAAAPAAVALAPAPPAQAA 456

                          90       100       110
                  ....*....|....*....|....*....|....
gi 1593208012 675 PRPRA-PQTSSPPPVRRGASASPQGRQSPSPSTR 707
Cdd:PRK14951  457 PETVAiPVRVAPEPAVASAAPAPAAAPAAARLTP 490
KAR9 pfam08580
Yeast cortical protein KAR9; The KAR9 protein in Saccharomyces cerevisiae is a cytoskeletal ...
 594-729 2.58e-03

Yeast cortical protein KAR9; The KAR9 protein in Saccharomyces cerevisiae is a cytoskeletal protein required for karyogamy, correct positioning of the mitotic spindle and for orientation of cytoplasmic microtubules. KAR9 localizes at the shmoo tip in mating cells and at the tip of the growing bud in anaphase.


Pssm-ID: 430088 [Multi-domain]  Cd Length: 684  Bit Score: 41.35  E-value: 2.58e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1593208012 594 SPSPPPKRRTASPPPPPKRRASPSPPPKRRVSHSPPPKQRSPTvtKRRSPSLSSKHRKGSSpgRSTREARSPQPNKRHSP 673
Cdd:pfam08580 483 STLKQTKRPSKIPRASPNHSGFLSTPSNTATSETPTPALRPPS--RPQPPPPGNRPRWNAS--TNTNDLDVGHNFKPLTL 558

                          90       100       110       120       130       140
                  ....*....|....*....|....*....|....*....|....*....|....*....|....
gi 1593208012 674 SPRPRAPQTSSPP--------PVRRGASASPqgrqspSPSTRPIRRVSRTPEPKKIKKAASPSP 729
Cdd:pfam08580 559 TTPSPTPSRSSRSsstlppvsPLSRDKSRSP------APTCRSVSRASRRRASRKPTRIGSPNS 616
PHA03247 PHA03247
large tegument protein UL36; Provisional
 551-785 3.04e-03

large tegument protein UL36; Provisional


Pssm-ID: 223021 [Multi-domain]  Cd Length: 3151  Bit Score: 41.46  E-value: 3.04e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1593208012  551 PPPPPPRRRRSPTPPPRRRTPSPPPRRRSPSPRRYSPPIQRRYS-------PSPPPK--RRTASPPP---------PPKR 612
Cdd:PHA03247  2625 DPPPPSPSPAANEPDPHPPPTVPPPERPRDDPAPGRVSRPRRARrlgraaqASSPPQrpRRRAARPTvgsltsladPPPP 2704

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1593208012  613 RASPSPPPKRRVSHSPPP------KQRSPTVTKRRSPSLSSKhrKGSSPGRSTREARSPQPNKRHSPSPrPRAPQTSSPP 686
Cdd:PHA03247  2705 PPTPEPAPHALVSATPLPpgpaaaRQASPALPAAPAPPAVPA--GPATPGGPARPARPPTTAGPPAPAP-PAAPAAGPPR 2781

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1593208012  687 --PVRRGASASPQGRQSPSPSTRPIRRVSRTPEPKKIKKAASPSPQSVRRVSSSRSVSGSPEPAAKKPPAPPSPVQ---- 760
Cdd:PHA03247  2782 rlTRPAVASLSESRESLPSPWDPADPPAAVLAPAAALPPAASPAGPLPPPTSAQPTAPPPPPGPPPPSLPLGGSVApggd 2861

                          250       260
                   ....*....|....*....|....*.
gi 1593208012  761 -SQSPSTNWSPAVPAKKAKSPTPSLS 785
Cdd:PHA03247  2862 vRRRPPSRSPAAKPAAPARPPVRRLA 2887
PHA03307 PHA03307
transcriptional regulator ICP4; Provisional
 550-786 4.27e-03

transcriptional regulator ICP4; Provisional


Pssm-ID: 223039 [Multi-domain]  Cd Length: 1352  Bit Score: 40.92  E-value: 4.27e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1593208012  550 PPPPPPPRRRRSPTPPPRRRTPSPPPRRRSPSPRRYSPPIQRRYSPSPPPKRRTASPPPPPKRRASPSPPPKRRVSHSPP 629
Cdd:PHA03307   128 PSPAPDLSEMLRPVGSPGPPPAASPPAAGASPAAVASDAASSRQAALPLSSPEETARAPSSPPAEPPPSTPPAAASPRPP 207

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1593208012  630 PKQRSPTVTKRRSPSLSSKHRKGSSPGRSTREARSPQPNKRHSP---SPRPRAPQTSSPPPVRRGASASPQG-RQSPSPS 705
Cdd:PHA03307   208 RRSSPISASASSPAPAPGRSAADDAGASSSDSSSSESSGCGWGPeneCPLPRPAPITLPTRIWEASGWNGPSsRPGPASS 287

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1593208012  706 TRPIRRVSRTPEPKKIKKAASPSPQSVRRVSSSRSVSGSPEPAAKKPPAPPSPV-------QSQSPSTNWSPAVPAKKAK 778
Cdd:PHA03307   288 SSSPRERSPSPSPSSPGSGPAPSSPRASSSSSSSRESSSSSTSSSSESSRGAAVspgpspsRSPSPSRPPPPADPSSPRK 367


                   ....*...
gi 1593208012  779 SPTPSLSP 786
Cdd:PHA03307   368 RPRPSRAP 375
PHA03247 PHA03247
large tegument protein UL36; Provisional
 592-729 6.45e-03

large tegument protein UL36; Provisional


Pssm-ID: 223021 [Multi-domain]  Cd Length: 3151  Bit Score: 40.31  E-value: 6.45e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1593208012  592 RYSPSPPPKRRTASPPP----------------PPKRRASPSPPPK----------------RRVSHSPPPKQRSPT-VT 638
Cdd:PHA03247   273 RGATGPPPPPEAAAPNGaaappdgvwgaalagaPLALPAPPDPPPPapagdaeeeddedgamEVVSPLPRPRQHYPLgFP 352

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1593208012  639 KRRSPS---------LSS--KHRKGSSPG----RSTREARSP---QPNKRHSPSPRPRAPQTSSPPPVRRGASASPQGRQ 700
Cdd:PHA03247   353 KRRRPTwtppssledLSAgrHHPKRASLPtrkrRSARHAATPfarGPGGDDQTRPAAPVPASVPTPAPTPVPASAPPPPA 432

                          170       180
                   ....*....|....*....|....*....
gi 1593208012  701 SPSPSTRPIRRVSRTPEPKKIKKAASPSP 729
Cdd:PHA03247   433 TPLPSAEPGSDDGPAPPPERQPPAPATEP 461
PRK07994 PRK07994
DNA polymerase III subunits gamma and tau; Validated
 595-729 8.00e-03

DNA polymerase III subunits gamma and tau; Validated


Pssm-ID: 236138 [Multi-domain]  Cd Length: 647  Bit Score: 39.85  E-value: 8.00e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1593208012 595 PSPPPKRRTASPPPPPKRRASPSPPPkrrvshSPPPKQRSPTVTKRRSPSLSSKHrkgsspgrSTREARSPQPNKRHSPS 674
Cdd:PRK07994  379 ASAQATAAPTAAVAPPQAPAVPPPPA------SAPQQAPAVPLPETTSQLLAARQ--------QLQRAQGATKAKKSEPA 444

                          90       100       110       120       130
                  ....*....|....*....|....*....|....*....|....*....|....*
gi 1593208012 675 PRPRAPQTSSPPPVRRGASASPQGRQSPSPSTRPIRRVSRTPEPKKIKKAASPSP 729
Cdd:PRK07994  445 AASRARPVNSALERLASVRPAPSALEKAPAKKEAYRWKATNPVEVKKEPVATPKA 499
PRK07764 PRK07764
DNA polymerase III subunits gamma and tau; Validated
 652-876 9.21e-03

DNA polymerase III subunits gamma and tau; Validated


Pssm-ID: 236090 [Multi-domain]  Cd Length: 824  Bit Score: 39.58  E-value: 9.21e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1593208012 652 GSSPGRSTREARSPQPNKRHSPSPRPRAPQTSSPPPVRRGASASPQGRQSPSPSTRPIrrvsrTPEPKKIKKAASPSPQS 731
Cdd:PRK07764  590 PAPGAAGGEGPPAPASSGPPEEAARPAAPAAPAAPAAPAPAGAAAAPAEASAAPAPGV-----AAPEHHPKHVAVPDASD 664

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1593208012 732 VRRVSSSRSVSGSPEPAAKKPPAPPSPVQSQSPSTNWSPAVPAKKAKSPTPSLSPARNSDQEGGGKKKKKKKDKKHKKDK 811
Cdd:PRK07764  665 GGDGWPAKAGGAAPAAPPPAPAPAAPAAPAGAAPAQPAPAPAATPPAGQADDPAAQPPQAAQGASAPSPAADDPVPLPPE 744

                         170       180       190       200       210       220
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 1593208012 812 KHKKHKKHKKEKAVTIATPATAAPAAVSAATTTSAQEEPA----AAPEPRKETESEAEDDNLDDLERHL 876
Cdd:PRK07764  745 PDDPPDPAGAPAQPPPPPAPAPAAAPAAAPPPSPPSEEEEmaedDAPSMDDEDRRDAEEVAMELLEEEL 813
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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