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Conserved domains on  [gi|1593208031|ref|NP_001356003|]
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serine/arginine repetitive matrix protein 1 isoform 10 [Mus musculus]

Protein Classification

PWI domain-containing protein( domain architecture ID 10478549)

PWI domain-containing protein may function as a splicing factor; similar to Homo sapiens serine/arginine repetitive matrix protein 1 that is involved in numerous pre-mRNA processing events

CATH:  1.20.1390.10
Gene Ontology:  GO:0006397|GO:0003676
PubMed:  10322432|12600940
SCOP:  4000671

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
PWI pfam01480
PWI domain;
1-32 8.42e-12

PWI domain;


:

Pssm-ID: 460224 [Multi-domain]  Cd Length: 71  Bit Score: 60.98  E-value: 8.42e-12
                          10        20        30
                  ....*....|....*....|....*....|..
gi 1593208031   1 MMQINLTGFLNgKNAREFMGELWPLLLSAQEN 32
Cdd:pfam01480  39 ELQIQLTGFLD-KDAAKFVKELWKLLLSAQES 69
PHA03307 super family cl33723
transcriptional regulator ICP4; Provisional
 511-708 6.52e-05

transcriptional regulator ICP4; Provisional


The actual alignment was detected with superfamily member PHA03307:

Pssm-ID: 223039 [Multi-domain]  Cd Length: 1352  Bit Score: 46.70  E-value: 6.52e-05
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1593208031  511 SPSPPPKRRTASPPPPPKRRASPSPPPKRRVSHSPPPKQRSPTVTKRRSPSLSSKHRKGSSPGRSTREARSPQPNkrhSP 590
Cdd:PHA03307   101 AREGSPTPPGPSSPDPPPPTPPPASPPPSPAPDLSEMLRPVGSPGPPPAASPPAAGASPAAVASDAASSRQAALP---LS 177

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1593208031  591 SPRPRAPQTSSPPPVRRGASASPQGRQSPSPSTRPIRRVSRTPEPKKIKKAASPSPQSVRRVSSSRSVSGSPEPAAKKPP 670
Cdd:PHA03307   178 SPEETARAPSSPPAEPPPSTPPAAASPRPPRRSSPISASASSPAPAPGRSAADDAGASSSDSSSSESSGCGWGPENECPL 257

                          170       180       190
                   ....*....|....*....|....*....|....*...
gi 1593208031  671 APPSPVQSQSPSTNWSPAVPAKKAKSPTPSLSPARNSD 708
Cdd:PHA03307   258 PRPAPITLPTRIWEASGWNGPSSRPGPASSSSSPRERS 295
 
Name Accession Description Interval E-value
PWI pfam01480
PWI domain;
1-32 8.42e-12

PWI domain;


Pssm-ID: 460224 [Multi-domain]  Cd Length: 71  Bit Score: 60.98  E-value: 8.42e-12
                          10        20        30
                  ....*....|....*....|....*....|..
gi 1593208031   1 MMQINLTGFLNgKNAREFMGELWPLLLSAQEN 32
Cdd:pfam01480  39 ELQIQLTGFLD-KDAAKFVKELWKLLLSAQES 69
PHA03307 PHA03307
transcriptional regulator ICP4; Provisional
 511-708 6.52e-05

transcriptional regulator ICP4; Provisional


Pssm-ID: 223039 [Multi-domain]  Cd Length: 1352  Bit Score: 46.70  E-value: 6.52e-05
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1593208031  511 SPSPPPKRRTASPPPPPKRRASPSPPPKRRVSHSPPPKQRSPTVTKRRSPSLSSKHRKGSSPGRSTREARSPQPNkrhSP 590
Cdd:PHA03307   101 AREGSPTPPGPSSPDPPPPTPPPASPPPSPAPDLSEMLRPVGSPGPPPAASPPAAGASPAAVASDAASSRQAALP---LS 177

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1593208031  591 SPRPRAPQTSSPPPVRRGASASPQGRQSPSPSTRPIRRVSRTPEPKKIKKAASPSPQSVRRVSSSRSVSGSPEPAAKKPP 670
Cdd:PHA03307   178 SPEETARAPSSPPAEPPPSTPPAAASPRPPRRSSPISASASSPAPAPGRSAADDAGASSSDSSSSESSGCGWGPENECPL 257

                          170       180       190
                   ....*....|....*....|....*....|....*...
gi 1593208031  671 APPSPVQSQSPSTNWSPAVPAKKAKSPTPSLSPARNSD 708
Cdd:PHA03307   258 PRPAPITLPTRIWEASGWNGPSSRPGPASSSSSPRERS 295
PWI smart00311
PWI, domain in splicing factors;
1-32 2.18e-04

PWI, domain in splicing factors;


Pssm-ID: 214609 [Multi-domain]  Cd Length: 74  Bit Score: 40.41  E-value: 2.18e-04
                           10        20        30
                   ....*....|....*....|....*....|..
gi 1593208031    1 MMQINLTGFLNgknAREFMGELWPLLLSAQEN 32
Cdd:smart00311  46 LLQINLTGFED---AEEFVDKLWRLLIFELKN 74
Pneumo_att_G pfam05539
Pneumovirinae attachment membrane glycoprotein G;
514-647 1.38e-03

Pneumovirinae attachment membrane glycoprotein G;


Pssm-ID: 114270 [Multi-domain]  Cd Length: 408  Bit Score: 41.96  E-value: 1.38e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1593208031 514 PPPKRRTASPPPPPKRRASPSPPPKRRVSHSPPPKQRSPTVTKRRSPSLSSKHRKGSSPGRSTREARSPQPNKRHSPSPR 593
Cdd:pfam05539 168 PKTAVTTSKTTSWPTEVSHPTYPSQVTPQSQPATQGHQTATANQRLSSTEPVGTQGTTTSSNPEPQTEPPPSQRGPSGSP 247

                          90       100       110       120       130
                  ....*....|....*....|....*....|....*....|....*....|....*..
gi 1593208031 594 PRAPQTSSPPPVRRGASA--SPQGRQSPSPS-TRPIRRVSRTPEPKKIKKAASPSPQ 647
Cdd:pfam05539 248 QHPPSTTSQDQSTTGDGQehTQRRKTPPATSnRRSPHSTATPPPTTKRQETGRPTPR 304
 
Name Accession Description Interval E-value
PWI pfam01480
PWI domain;
1-32 8.42e-12

PWI domain;


Pssm-ID: 460224 [Multi-domain]  Cd Length: 71  Bit Score: 60.98  E-value: 8.42e-12
                          10        20        30
                  ....*....|....*....|....*....|..
gi 1593208031   1 MMQINLTGFLNgKNAREFMGELWPLLLSAQEN 32
Cdd:pfam01480  39 ELQIQLTGFLD-KDAAKFVKELWKLLLSAQES 69
PHA03307 PHA03307
transcriptional regulator ICP4; Provisional
 511-708 6.52e-05

transcriptional regulator ICP4; Provisional


Pssm-ID: 223039 [Multi-domain]  Cd Length: 1352  Bit Score: 46.70  E-value: 6.52e-05
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1593208031  511 SPSPPPKRRTASPPPPPKRRASPSPPPKRRVSHSPPPKQRSPTVTKRRSPSLSSKHRKGSSPGRSTREARSPQPNkrhSP 590
Cdd:PHA03307   101 AREGSPTPPGPSSPDPPPPTPPPASPPPSPAPDLSEMLRPVGSPGPPPAASPPAAGASPAAVASDAASSRQAALP---LS 177

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1593208031  591 SPRPRAPQTSSPPPVRRGASASPQGRQSPSPSTRPIRRVSRTPEPKKIKKAASPSPQSVRRVSSSRSVSGSPEPAAKKPP 670
Cdd:PHA03307   178 SPEETARAPSSPPAEPPPSTPPAAASPRPPRRSSPISASASSPAPAPGRSAADDAGASSSDSSSSESSGCGWGPENECPL 257

                          170       180       190
                   ....*....|....*....|....*....|....*...
gi 1593208031  671 APPSPVQSQSPSTNWSPAVPAKKAKSPTPSLSPARNSD 708
Cdd:PHA03307   258 PRPAPITLPTRIWEASGWNGPSSRPGPASSSSSPRERS 295
PHA03247 PHA03247
large tegument protein UL36; Provisional
 511-706 8.87e-05

large tegument protein UL36; Provisional


Pssm-ID: 223021 [Multi-domain]  Cd Length: 3151  Bit Score: 46.47  E-value: 8.87e-05
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1593208031  511 SPSPPPKRRTASPPPPPKRRASPSPPPKRRVShSPPPKQRSPTVTKRRSPSLSSKHRKGSSPGRST-REARSPQPNKRHS 589
Cdd:PHA03247  2753 GPARPARPPTTAGPPAPAPPAAPAAGPPRRLT-RPAVASLSESRESLPSPWDPADPPAAVLAPAAAlPPAASPAGPLPPP 2831

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1593208031  590 PSPRPRAPQTSSPP---------------PVRRGASASPQGRQSPSPSTRPIRRVSRTPEPKKIKKAASPSPQSVRRVSS 654
Cdd:PHA03247  2832 TSAQPTAPPPPPGPpppslplggsvapggDVRRRPPSRSPAAKPAAPARPPVRRLARPAVSRSTESFALPPDQPERPPQP 2911

                          170       180       190       200       210
                   ....*....|....*....|....*....|....*....|....*....|...
gi 1593208031  655 SRSVSGSPEPAAKKPPAPPSPVQSQS-PSTNWSPAVPAKKAKSPTPSLSPARN 706
Cdd:PHA03247  2912 QAPPPPQPQPQPPPPPQPQPPPPPPPrPQPPLAPTTDPAGAGEPSGAVPQPWL 2964
PRK07764 PRK07764
DNA polymerase III subunits gamma and tau; Validated
 509-704 1.60e-04

DNA polymerase III subunits gamma and tau; Validated


Pssm-ID: 236090 [Multi-domain]  Cd Length: 824  Bit Score: 45.36  E-value: 1.60e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1593208031 509 RYSPSPPPKRRTASPPPPPKRRASPSPPPKRRVSHSPPPKQRSPTVTKRRSPSLSSKHRKGSSPGRSTREARSPQPNKRH 588
Cdd:PRK07764  585 EAVVGPAPGAAGGEGPPAPASSGPPEEAARPAAPAAPAAPAAPAPAGAAAAPAEASAAPAPGVAAPEHHPKHVAVPDASD 664

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1593208031 589 SPSPRPR----APQTSSPPPVRRGASASPQGRQSPSPSTRPirRVSRTPEPKKIKKAASPSPQSVRRVSSSRSVSGSPEP 664
Cdd:PRK07764  665 GGDGWPAkaggAAPAAPPPAPAPAAPAAPAGAAPAQPAPAP--AATPPAGQADDPAAQPPQAAQGASAPSPAADDPVPLP 742

                         170       180       190       200
                  ....*....|....*....|....*....|....*....|
gi 1593208031 665 AAKKPPAPPSPVQSQSPSTNWSPAVPAKKAKSPTPSLSPA 704
Cdd:PRK07764  743 PEPDDPPDPAGAPAQPPPPPAPAPAAAPAAAPPPSPPSEE 782
PRK12323 PRK12323
DNA polymerase III subunit gamma/tau;
512-704 1.94e-04

DNA polymerase III subunit gamma/tau;


Pssm-ID: 237057 [Multi-domain]  Cd Length: 700  Bit Score: 44.87  E-value: 1.94e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1593208031 512 PSPPPKRRTASPPPPPKRRASPSPPPKRRVSHSPP---PKQRSPTVTKRRSPSLSSKHRKGSSPGRSTREARSPQPNKRH 588
Cdd:PRK12323  385 PAPAAAAPAAAAPAPAAPPAAPAAAPAAAAAARAVaaaPARRSPAPEALAAARQASARGPGGAPAPAPAPAAAPAAAARP 464

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1593208031 589 SPSPRPRAPQTSSPPPVRRGASASPQGRQSPSPSTRPIRRVSRTPEPKKIKKAASPSPQSVRRVSSSRSVSGSPEPAAKK 668
Cdd:PRK12323  465 AAAGPRPVAAAAAAAPARAAPAAAPAPADDDPPPWEELPPEFASPAPAQPDAAPAGWVAESIPDPATADPDDAFETLAPA 544

                         170       180       190
                  ....*....|....*....|....*....|....*.
gi 1593208031 669 PPAPPSPVQSqSPSTNWSPAVPAKKAKSPTPSLSPA 704
Cdd:PRK12323  545 PAAAPAPRAA-AATEPVVAPRPPRASASGLPDMFDG 579
PWI smart00311
PWI, domain in splicing factors;
1-32 2.18e-04

PWI, domain in splicing factors;


Pssm-ID: 214609 [Multi-domain]  Cd Length: 74  Bit Score: 40.41  E-value: 2.18e-04
                           10        20        30
                   ....*....|....*....|....*....|..
gi 1593208031    1 MMQINLTGFLNgknAREFMGELWPLLLSAQEN 32
Cdd:smart00311  46 LLQINLTGFED---AEEFVDKLWRLLIFELKN 74
PHA03307 PHA03307
transcriptional regulator ICP4; Provisional
 265-614 6.96e-04

transcriptional regulator ICP4; Provisional


Pssm-ID: 223039 [Multi-domain]  Cd Length: 1352  Bit Score: 43.24  E-value: 6.96e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1593208031  265 SPPRKTRRLSPSASPPRRRHRPSSPATPPPktrhSPTPQQSNRTRKSRVSVSPGRTSGKVTKHKGTEKRESPSPAPKPRK 344
Cdd:PHA03307    99 SPAREGSPTPPGPSSPDPPPPTPPPASPPP----SPAPDLSEMLRPVGSPGPPPAASPPAAGASPAAVASDAASSRQAAL 174

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1593208031  345 VELSESEEDKGSKMAAADSVQQRRQYRRQNQQSSSDSGSSSTSEDERPKRSHVKNGEVGRRRRHSPSRSASPSPRKRQKE 424
Cdd:PHA03307   175 PLSSPEETARAPSSPPAEPPPSTPPAAASPRPPRRSSPISASASSPAPAPGRSAADDAGASSSDSSSSESSGCGWGPENE 254

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1593208031  425 TSPRMqmgkrwqsPVTKSSRRRRSPSPPPARRRRSPSPAPPPPPPPPPPRRRRSPTPPPRRRTPSPPPRRRSPSPRRYSP 504
Cdd:PHA03307   255 CPLPR--------PAPITLPTRIWEASGWNGPSSRPGPASSSSSPRERSPSPSPSSPGSGPAPSSPRASSSSSSSRESSS 326

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1593208031  505 PIQRRYSPSPppkrRTASPPPPPKRRASPSPPPKRRVSHSPPPKQRSPTVTKRRSPSLSskhrKGSSPGRSTREARSPQP 584
Cdd:PHA03307   327 SSTSSSSESS----RGAAVSPGPSPSRSPSPSRPPPPADPSSPRKRPRPSRAPSSPAAS----AGRPTRRRARAAVAGRA 398

                          330       340       350
                   ....*....|....*....|....*....|
gi 1593208031  585 NKRHSPSPRPRAPQTSSPPPVRRGASASPQ 614
Cdd:PHA03307   399 RRRDATGRFPAGRPRPSPLDAGAASGAFYA 428
PHA03307 PHA03307
transcriptional regulator ICP4; Provisional
 512-712 1.00e-03

transcriptional regulator ICP4; Provisional


Pssm-ID: 223039 [Multi-domain]  Cd Length: 1352  Bit Score: 42.85  E-value: 1.00e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1593208031  512 PSPPPKRRTASPPPPPKRRASPSPPPKRRVSHSPPPKQRSPTVTKRRSPSLSSKHRKGSSPGRSTREARSPQPNK----- 586
Cdd:PHA03307   115 DPPPPTPPPASPPPSPAPDLSEMLRPVGSPGPPPAASPPAAGASPAAVASDAASSRQAALPLSSPEETARAPSSPpaepp 194

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1593208031  587 ----RHSPSPRPRAPQTSSPPPVRRGASASPQGRQSPSPSTRPIRRVSRTPEPKKIKKAASPSPQSVRRVSSSRSVSGSP 662
Cdd:PHA03307   195 pstpPAAASPRPPRRSSPISASASSPAPAPGRSAADDAGASSSDSSSSESSGCGWGPENECPLPRPAPITLPTRIWEASG 274

                          170       180       190       200       210
                   ....*....|....*....|....*....|....*....|....*....|.
gi 1593208031  663 EPAAKKPPAPPSPVQS-QSPSTNWSPAVPAKKAKSPTPSLSPARNSDQEGG 712
Cdd:PHA03307   275 WNGPSSRPGPASSSSSpRERSPSPSPSSPGSGPAPSSPRASSSSSSSRESS 325
Pneumo_att_G pfam05539
Pneumovirinae attachment membrane glycoprotein G;
514-647 1.38e-03

Pneumovirinae attachment membrane glycoprotein G;


Pssm-ID: 114270 [Multi-domain]  Cd Length: 408  Bit Score: 41.96  E-value: 1.38e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1593208031 514 PPPKRRTASPPPPPKRRASPSPPPKRRVSHSPPPKQRSPTVTKRRSPSLSSKHRKGSSPGRSTREARSPQPNKRHSPSPR 593
Cdd:pfam05539 168 PKTAVTTSKTTSWPTEVSHPTYPSQVTPQSQPATQGHQTATANQRLSSTEPVGTQGTTTSSNPEPQTEPPPSQRGPSGSP 247

                          90       100       110       120       130
                  ....*....|....*....|....*....|....*....|....*....|....*..
gi 1593208031 594 PRAPQTSSPPPVRRGASA--SPQGRQSPSPS-TRPIRRVSRTPEPKKIKKAASPSPQ 647
Cdd:pfam05539 248 QHPPSTTSQDQSTTGDGQehTQRRKTPPATSnRRSPHSTATPPPTTKRQETGRPTPR 304
PRK14951 PRK14951
DNA polymerase III subunits gamma and tau; Provisional
 509-635 1.45e-03

DNA polymerase III subunits gamma and tau; Provisional


Pssm-ID: 237865 [Multi-domain]  Cd Length: 618  Bit Score: 42.01  E-value: 1.45e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1593208031 509 RYSPSPPPKRRTASPPPPPKRRASPSPPPKR---RVSHSPPPKQRSPTVTkrrSPSlsskhrkGSSPGRSTREARSPQPN 585
Cdd:PRK14951  367 AAAAEAAAPAEKKTPARPEAAAPAAAPVAQAaaaPAPAAAPAAAASAPAA---PPA-------AAPPAPVAAPAAAAPAA 436

                          90       100       110       120       130
                  ....*....|....*....|....*....|....*....|....*....|
gi 1593208031 586 KRHsPSPRPRAPQTSSPPPVRRGASASPQgRQSPSPSTRPIRRVSRTPEP 635
Cdd:PRK14951  437 APA-AAPAAVALAPAPPAQAAPETVAIPV-RVAPEPAVASAAPAPAAAPA 484
PRK14951 PRK14951
DNA polymerase III subunits gamma and tau; Provisional
 512-624 2.56e-03

DNA polymerase III subunits gamma and tau; Provisional


Pssm-ID: 237865 [Multi-domain]  Cd Length: 618  Bit Score: 41.24  E-value: 2.56e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1593208031 512 PSPPPKRRTASPPPPPKRRASPSPPPKRRVshsPPPKQRSPTVTKrrspslsskhrkgSSPGRSTREARSPQPNKRHSPS 591
Cdd:PRK14951  393 PVAQAAAAPAPAAAPAAAASAPAAPPAAAP---PAPVAAPAAAAP-------------AAAPAAAPAAVALAPAPPAQAA 456

                          90       100       110
                  ....*....|....*....|....*....|....
gi 1593208031 592 PRPRA-PQTSSPPPVRRGASASPQGRQSPSPSTR 624
Cdd:PRK14951  457 PETVAiPVRVAPEPAVASAAPAPAAAPAAARLTP 490
PRK07764 PRK07764
DNA polymerase III subunits gamma and tau; Validated
 511-676 4.87e-03

DNA polymerase III subunits gamma and tau; Validated


Pssm-ID: 236090 [Multi-domain]  Cd Length: 824  Bit Score: 40.35  E-value: 4.87e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1593208031 511 SPSPPPKRRTASPPPPPkRRASPSPPPKRRVSHSPPPKQRSPTVTKRRSPS-LSSKHRKGSSPGRSTREARSPQPNKRHS 589
Cdd:PRK07764  620 APAAPAAPAPAGAAAAP-AEASAAPAPGVAAPEHHPKHVAVPDASDGGDGWpAKAGGAAPAAPPPAPAPAAPAAPAGAAP 698

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1593208031 590 PSPRPRAPQTSSPPPVRRGASASPQGRQSPS-PSTRPIRRVSRTPEPKKIKKAASPSPQSVRRVSSSRSVSGSPEPAAKK 668
Cdd:PRK07764  699 AQPAPAPAATPPAGQADDPAAQPPQAAQGASaPSPAADDPVPLPPEPDDPPDPAGAPAQPPPPPAPAPAAAPAAAPPPSP 778


                  ....*...
gi 1593208031 669 PPAPPSPV 676
Cdd:PRK07764  779 PSEEEEMA 786
KAR9 pfam08580
Yeast cortical protein KAR9; The KAR9 protein in Saccharomyces cerevisiae is a cytoskeletal ...
 511-646 6.56e-03

Yeast cortical protein KAR9; The KAR9 protein in Saccharomyces cerevisiae is a cytoskeletal protein required for karyogamy, correct positioning of the mitotic spindle and for orientation of cytoplasmic microtubules. KAR9 localizes at the shmoo tip in mating cells and at the tip of the growing bud in anaphase.


Pssm-ID: 430088 [Multi-domain]  Cd Length: 684  Bit Score: 40.20  E-value: 6.56e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1593208031 511 SPSPPPKRRTASPPPPPKRRASPSPPPKRRVSHSPPPKQRSPTvtKRRSPSLSSKHRKGSSpgRSTREARSPQPNKRHSP 590
Cdd:pfam08580 483 STLKQTKRPSKIPRASPNHSGFLSTPSNTATSETPTPALRPPS--RPQPPPPGNRPRWNAS--TNTNDLDVGHNFKPLTL 558

                          90       100       110       120       130       140
                  ....*....|....*....|....*....|....*....|....*....|....*....|....
gi 1593208031 591 SPRPRAPQTSSPP--------PVRRGASASPqgrqspSPSTRPIRRVSRTPEPKKIKKAASPSP 646
Cdd:pfam08580 559 TTPSPTPSRSSRSsstlppvsPLSRDKSRSP------APTCRSVSRASRRRASRKPTRIGSPNS 616
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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