NCBI Home Page NCBI Site Search page NCBI Guide that lists and describes the NCBI resources
Conserved domains on  [gi|1700611639|ref|NP_001358303|]
View 

MAP3K7 C-terminal-like protein isoform 2 [Homo sapiens]

Protein Classification

Graphical summary

 Zoom to residue level

show extra options »

Show site features     Horizontal zoom: ×

List of domain hits

 Name Accession Description Interval E-value
Smc super family cl34174
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ...
 38-139 8.71e-03

Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];


The actual alignment was detected with superfamily member COG1196:

Pssm-ID: 440809 [Multi-domain]  Cd Length: 983  Bit Score: 35.30  E-value: 8.71e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1700611639  38 ELDQQLQPLppchdseesmevfKQHCQIAEEYHEVKKEITLLE---------QRKKELIAKLDQAEKEKVDAAELVREFE 108
Cdd:COG1196   197 ELERQLEPL-------------ERQAEKAERYRELKEELKELEaellllklrELEAELEELEAELEELEAELEELEAELA 263

                          90       100       110
                  ....*....|....*....|....*....|.
gi 1700611639 109 ALTEENRTLRLAQSQCVEQLEKLRIQYQKRQ 139
Cdd:COG1196   264 ELEAELEELRLELEELELELEEAQAEEYELL 294
 
Name Accession Description Interval E-value
Smc COG1196
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ...
 38-139 8.71e-03

Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 440809 [Multi-domain]  Cd Length: 983  Bit Score: 35.30  E-value: 8.71e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1700611639  38 ELDQQLQPLppchdseesmevfKQHCQIAEEYHEVKKEITLLE---------QRKKELIAKLDQAEKEKVDAAELVREFE 108
Cdd:COG1196   197 ELERQLEPL-------------ERQAEKAERYRELKEELKELEaellllklrELEAELEELEAELEELEAELEELEAELA 263

                          90       100       110
                  ....*....|....*....|....*....|.
gi 1700611639 109 ALTEENRTLRLAQSQCVEQLEKLRIQYQKRQ 139
Cdd:COG1196   264 ELEAELEELRLELEELELELEEAQAEEYELL 294
 
Name Accession Description Interval E-value
Smc COG1196
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ...
 38-139 8.71e-03

Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 440809 [Multi-domain]  Cd Length: 983  Bit Score: 35.30  E-value: 8.71e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1700611639  38 ELDQQLQPLppchdseesmevfKQHCQIAEEYHEVKKEITLLE---------QRKKELIAKLDQAEKEKVDAAELVREFE 108
Cdd:COG1196   197 ELERQLEPL-------------ERQAEKAERYRELKEELKELEaellllklrELEAELEELEAELEELEAELEELEAELA 263

                          90       100       110
                  ....*....|....*....|....*....|.
gi 1700611639 109 ALTEENRTLRLAQSQCVEQLEKLRIQYQKRQ 139
Cdd:COG1196   264 ELEAELEELRLELEELELELEEAQAEEYELL 294
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
Help | Disclaimer | Write to the Help Desk
NCBI | NLM | NIH