|
Name |
Accession |
Description |
Interval |
E-value |
| CitT |
COG0471 |
Di- and tricarboxylate antiporter [Carbohydrate transport and metabolism]; |
128-588 |
6.77e-84 |
|
Di- and tricarboxylate antiporter [Carbohydrate transport and metabolism];
Pssm-ID: 440239 [Multi-domain] Cd Length: 369 Bit Score: 267.02 E-value: 6.77e-84
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1732634002 128 LGSLIVAVAVERWKLHKRVALRMLLFVGTKPSRLMLGFMFVTAFLSMWISNTAATAMMIPIVEAMLQQMiaantaveasl 207
Cdd:COG0471 1 LGGFVLAAALEKTGLGRRIALLLLKRFGGSPLRLLLGLMLATALLSAFISNTARAAMMLPIALSIAAAL----------- 69
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1732634002 208 gtlelldknktselpgsqvvfedpnvqeqEDEETKNMYKAMHLCVCYSASIGGTATLTGTGPNVVLLGQMQELFPDSkdv 287
Cdd:COG0471 70 -----------------------------GSEKRSKFGSALLLPIAFAASIGGMGTLIGTPPNLIAAGLLEEATGIP--- 117
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1732634002 288 LNYASWFGFAFPNMVMMLVLAWLWLqCLYMRHNLKKTciccgekkrdteKIAYKVLNEEYQKLGSLSYPECNVLFCFTLL 367
Cdd:COG0471 118 ISFFEWMLVGLPVALVGLLLLWLVL-YRLLPPEIKEV------------PGSKEVIREELAELGPLSRREKIALAIFALT 184
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1732634002 368 VILWFSRDPgfmpgwlsfawvegntVHITDATVAIFVAILLFIipsqkpkfnfssqteeerktpfypPALLDWKVAQEKV 447
Cdd:COG0471 185 VLLWITGSL----------------HGIPIAVVALLGAVLLLL------------------------TGVLTWKDAYKSI 224
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1732634002 448 PWDIVLLLGGGFAMAKGCETSGLSKWMAAQMEP-LRLVKPAVITLILSCLVAMTTECTSNVATTTLFLPIFASMARSIGI 526
Cdd:COG0471 225 PWGVLLLFGGGLALGAALEKTGLAAWLADALLPlLGGLSPLLLLLLLALLTLLLTEFASNTATAALLLPIAISLAQALGV 304
|
410 420 430 440 450 460
....*....|....*....|....*....|....*....|....*....|....*....|..
gi 1732634002 527 HPLYVMIPCTMSASLAFMLPVATPPNAIVFAYGHLRVVDMMKTGLIMNFVGILSVFLSVNTW 588
Cdd:COG0471 305 NPLPLALAVAFAASCAFLLPVGTPPNAIVYGSGYYKFKDFLKVGLPLNLIGLVVLLLLGPLW 366
|
|
| Na_sulph_symp |
pfam00939 |
Sodium:sulfate symporter transmembrane region; There are also some members in this family that ... |
50-595 |
1.60e-78 |
|
Sodium:sulfate symporter transmembrane region; There are also some members in this family that do not match the Prosite motif, and belong to the subfamily SODIT1.
Pssm-ID: 279307 [Multi-domain] Cd Length: 472 Bit Score: 256.53 E-value: 1.60e-78
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1732634002 50 SFAILLFTPILMLPLVILIPDKFARCAYVIVIMAVYWCTDVIPVAVTSLLPVLLFPLLKVLDSKQ----VCIQYMKDTNM 125
Cdd:pfam00939 8 LALLAVLLIILLLPAPDGLPSKAWHLFAIFIATIVGWILEPLPMAVIALFAISLSAILIGTLLAKalswALSGFSSTTTW 87
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1732634002 126 LFLGSLIVAVAVERWKLHKRVALRMLLFVGTKPsrLMLGFMFVTAFLSMWISNTAATAMMIPIVEAMLQQMIAANtavea 205
Cdd:pfam00939 88 LVFGAFFISAAFEKTGLGRRIALVLVKKMGKRT--LGLGYGLVFSDLLLAPATPSNTARAGGIVFPIIMSLPPAF----- 160
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1732634002 206 slgtlelldknktselpGSQVvfedpnvqeqEDEETKNMYKAMHLCVCYSASIGGTATLTGTGPNVVLLGQMQELfpdSK 285
Cdd:pfam00939 161 -----------------GSDP----------EKGSERRIGAYLMWTVYQSTSITSAMFLTAMAPNLLLLGLMNSI---LG 210
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1732634002 286 DVLNYASWFGFAFPNMVMMLVLAWLWLQCLYMrhnlkktciccGEKKRDTEkiAYKVLNEEYQKLGSLSYPECNVLFCFT 365
Cdd:pfam00939 211 VTITWASWFLAAIPPGVILLLLAPLLLYVLYP-----------PEIKSVPD--AKAIAKTELKELGPMTFREKALLGLFV 277
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1732634002 366 LLVILWFSrdpgfmpgwlsfawveGNTVHITDATVAIFVAILLFIIPsqkpkfnfssqteeerktpfyppaLLDWK-VAQ 444
Cdd:pfam00939 278 LLLLLWIF----------------GGSLNIDATTVAIIGLALMLLLR------------------------ILDWKdIVK 317
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1732634002 445 EKVPWDIVLLLGGGFAMAKGCETSGLSKWMAAQMEPL--RLVKPAVITLILSCLVAMTTECTSNVATTTLFLPIFASMAR 522
Cdd:pfam00939 318 NKGAWNTLIWLGGLIMLANGLERSGFIEWLGNTLSTSlsGFSPAMAFIIILSLFYLSHYLFASATAHTAAMLPIFAAVAQ 397
|
490 500 510 520 530 540 550
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 1732634002 523 SI-GIHPLYVMIPCTMSASLA-FMLPVATPPNAIVFAYGHLRVVDMMKTGLIMNFVGILSVFLSVNTWGRAMFNL 595
Cdd:pfam00939 398 AIpGAPPLLAALLLGFAISLGgFLTPYGTGPGPIYFGSGYLKVKDWWRIGAILTIIGLLILLLLGNWWWKPLGSL 472
|
|
| SLC13_permease |
cd01115 |
Permease SLC13 (solute carrier 13). The sodium/dicarboxylate cotransporter NaDC-1 has been ... |
76-585 |
5.77e-66 |
|
Permease SLC13 (solute carrier 13). The sodium/dicarboxylate cotransporter NaDC-1 has been shown to translocate Krebs cycle intermediates such as succinate, citrate, and alpha-ketoglutarate across plasma membranes rabbit, human, and rat kidney. It is related to renal and intestinal Na+/sulfate cotransporters and a few putative bacterial permeases. The SLC13-type proteins belong to the ArsB/NhaD superfamily of permeases that translocate sodium and various anions across biological membranes in all three kingdoms of life. A typical ArsB/NhaD permease is composed of 8-13 transmembrane helices.
Pssm-ID: 238535 [Multi-domain] Cd Length: 382 Bit Score: 220.53 E-value: 5.77e-66
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1732634002 76 AYVIVIMAVYWCTDVIPVAVTSLLPVLLFPLLKVLDSKQVCIQYMKDTNMLFLGSLIVAVAVERWKLHKRVALRMLLFVG 155
Cdd:cd01115 1 LAILVFAAVLFVTEALPLDVTALLVPVLLVLLGVVPPKEAFSGFSDPAVILFLAGFILGAALTRTGLAKRIATKLLKRAG 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1732634002 156 TKPSRLMLGFMFVTAFLSMWISNTAATAMMIPIVEAMLQQMIAANtaveaslgtlelldknktselpgsqvvfedpnvqe 235
Cdd:cd01115 81 KGERRLLLLLMLVTAFLSAFMSNTATVAIMLPVALGLAAKLDISP----------------------------------- 125
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1732634002 236 qedeetknmyKAMHLCVCYSASIGGTATLTGTGPNVVLLGQMQELFPDSkdvLNYASWFGFAFPNMVMMLVLAWLWLQcl 315
Cdd:cd01115 126 ----------SRLLMPLAFAASIGGMLTLIGTPPNLVASGYLESLGGQG---FSFFEFTPIGLPLLIIGLLYLWFIFR-- 190
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1732634002 316 ymrhnlkktciccgekkrdtekiaykvlneeyqklgslsypecNVLFCFTLLVILwfsrdpgfmpgwLSFAWVEGNTVHI 395
Cdd:cd01115 191 -------------------------------------------LAVLIITIVLLA------------ALAAITGLLPVSV 215
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1732634002 396 TDATVAIFVAILlfiipsqkpkfnfssqteeerktpfyppALLDWKVAQEKVPWDIVLLLGGGFAMAKGCETSGLSKWMA 475
Cdd:cd01115 216 AIAIGAIVLVFG----------------------------GVLLTKEDYKSIDWGIIFLFAGGIPLGKALESSGAAALIA 267
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1732634002 476 AQMEPLRLVKPAVITLILSCLVAMT-TECTSNVATTTLFLPIFASMARSIGIHPLYVMIPCTMSASLAFMLPVATPPNAI 554
Cdd:cd01115 268 EALISLLGGLPPFAILLLLCLLTLVlTNFISNTATAVLLAPIALSIALSLGLPPEALLLAVAIGASCAFMLPVGTPPNAI 347
|
490 500 510
....*....|....*....|....*....|.
gi 1732634002 555 VFAYGHLRVVDMMKTGLIMNfvgILSVFLSV 585
Cdd:cd01115 348 VLGPGGYKFSDFAKVGLPLS---ILSLVVSV 375
|
|
| dass |
TIGR00785 |
anion transporter; The Divalent Anion:Na+ Symporter (DASS) Family (TC 2.A.47) Functionally ... |
78-588 |
4.74e-46 |
|
anion transporter; The Divalent Anion:Na+ Symporter (DASS) Family (TC 2.A.47) Functionally characterized proteins of the DASS family transport (1) organic di- and tricarboxylates of the Krebs Cycle as well as dicarboxylate amino acid, (2) inorganic sulfate and (3) phosphate. The animal NaDC-1 cotransport 3 Na+ with each dicarboxylate. Protonated tricarboxylates are also cotransported with 3Na+. [Transport and binding proteins, Anions, Transport and binding proteins, Cations and iron carrying compounds]
Pssm-ID: 273267 [Multi-domain] Cd Length: 444 Bit Score: 168.68 E-value: 4.74e-46
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1732634002 78 VIVIMAVYWCTDVIPVAVTSLLPVLLFP----LLKVLDSKQVCIQYMKDTNMLFLGSLIVAVAVERWKLHKRVALRMLLF 153
Cdd:TIGR00785 16 IFVAAIVGWILEPLPLPVTALLAIPIIAvllgVLSAFKFKNALSGFADPTIWLFFGAFILATALVKTGLGKRIAYKLVGK 95
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1732634002 154 VGTKPSRL-MLGFMFVTAFLSMWISNTA-ATAMMIPIVEAMLQQMiaantaveaslgtlelldknktselpgsqvvfedp 231
Cdd:TIGR00785 96 MGGTTLGLgYFLVFLETLLAPMWPSNTArAGGILLPIIKSLLPLL----------------------------------- 140
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1732634002 232 nvQEQEDEETKNMYKAMHLCVCYSASIGGTATLTGTGPNVVLLGQMqelFPDSKDVLNYASWFGFAFPNMVMMLVLAWLW 311
Cdd:TIGR00785 141 --GSKPEKSPRKIGKYLMLGIAYSASIGSSGFLTGSAPNALAAGIL---SKILGIQISWGDWFLAGLPLGIILLLLVPLL 215
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1732634002 312 LQCLYmRHNLKKtciccgekKRDTEKIAykvlNEEYQKLGSLSYPEcnvlfcFTLLVILWFSRDPgfmpgwlsfaWVEGN 391
Cdd:TIGR00785 216 LYVLF-PPELKL--------KDEVDLWA----KEELEEMGPMSFRE------KALLGIFLLALLL----------WIFGG 266
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1732634002 392 TVHITDATVAIFVAILLFIIpsqkpkfnfssqteeerktpfyppALLDWK-VAQEKVPWDIVLLLGGGFAMAKGCETSGL 470
Cdd:TIGR00785 267 SLGINASVVALLAVVLMLFL------------------------GIVTWKdIQKNKVAWNTLILFGGLIGLAGGLKKSGF 322
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1732634002 471 SKWMAAQMEP--LRLVKPAVITLILSCLVAMTTECTSNVATTTLFLPIFASMARSIGIHPLYVMIPCTMSASLA-FMLPV 547
Cdd:TIGR00785 323 IKWFSEKLVGilDGLSPTIAVLVLVVLFYIILYFFASNTAHTAALVPIFFSVASAQGIPLELLALALALSASLMgFLTPY 402
|
490 500 510 520
....*....|....*....|....*....|....*....|.
gi 1732634002 548 ATPPNAIVFAYGHLRVVDMMKTGLIMNFVGILsVFLSVNTW 588
Cdd:TIGR00785 403 ATPPNAIAYGSGYVKIKDMWRVGAIIGIVGLI-VLLLVGTL 442
|
|
| CitMHS |
pfam03600 |
Citrate transporter; |
48-200 |
1.75e-05 |
|
Citrate transporter;
Pssm-ID: 460985 [Multi-domain] Cd Length: 342 Bit Score: 47.31 E-value: 1.75e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1732634002 48 FKSFAILLFTPILMLPLVILIPDKFARCAYVIVIMAVYWCTDVIPVAVTSLLPVLLFPLLKVLDSKQVCIQYMKDTNMLF 127
Cdd:pfam03600 181 FRKLLPVRKEEEAELEELRKRAIKDKLLLAISALVLALVILGFLLLSVLALAGALLLLLTGVLDPEEALKAVDWSTLLFF 260
|
90 100 110 120 130 140 150
....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 1732634002 128 LGSLIVAVAVERWKLHKRVALRMLLFVGtkPSRLMLGFMFVTAFLSMWISNTAATAMMIPIVEAMLQQMIAAN 200
Cdd:pfam03600 261 AGLFILVGALEKTGLADALADALGGLSG--LLVALALILWLSALLSAFISNVPTAALMAPIIVGMAPAAGLGD 331
|
|
| SLC13_permease |
cd01115 |
Permease SLC13 (solute carrier 13). The sodium/dicarboxylate cotransporter NaDC-1 has been ... |
48-203 |
5.09e-05 |
|
Permease SLC13 (solute carrier 13). The sodium/dicarboxylate cotransporter NaDC-1 has been shown to translocate Krebs cycle intermediates such as succinate, citrate, and alpha-ketoglutarate across plasma membranes rabbit, human, and rat kidney. It is related to renal and intestinal Na+/sulfate cotransporters and a few putative bacterial permeases. The SLC13-type proteins belong to the ArsB/NhaD superfamily of permeases that translocate sodium and various anions across biological membranes in all three kingdoms of life. A typical ArsB/NhaD permease is composed of 8-13 transmembrane helices.
Pssm-ID: 238535 [Multi-domain] Cd Length: 382 Bit Score: 46.04 E-value: 5.09e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1732634002 48 FKSFAILLFTPILMLPLVILIP---DKFARCAYVIVIMAvyWC-----TDVIPVAVTSLLPVLLFPLLKVLDSKQVCIQY 119
Cdd:cd01115 162 GQGFSFFEFTPIGLPLLIIGLLylwFIFRLAVLIITIVL--LAalaaiTGLLPVSVAIAIGAIVLVFGGVLLTKEDYKSI 239
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1732634002 120 MKDTNMLFLGSLIVAVAVERWKLHKRVAlRMLLFVGTK--PSRLMLGFMFVTAFLSMWISNTAATAMMIPIVEAMLQQMI 197
Cdd:cd01115 240 DWGIIFLFAGGIPLGKALESSGAAALIA-EALISLLGGlpPFAILLLLCLLTLVLTNFISNTATAVLLAPIALSIALSLG 318
|
....*.
gi 1732634002 198 AANTAV 203
Cdd:cd01115 319 LPPEAL 324
|
|
| |
|
Name |
Accession |
Description |
Interval |
E-value |
| CitT |
COG0471 |
Di- and tricarboxylate antiporter [Carbohydrate transport and metabolism]; |
128-588 |
6.77e-84 |
|
Di- and tricarboxylate antiporter [Carbohydrate transport and metabolism];
Pssm-ID: 440239 [Multi-domain] Cd Length: 369 Bit Score: 267.02 E-value: 6.77e-84
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1732634002 128 LGSLIVAVAVERWKLHKRVALRMLLFVGTKPSRLMLGFMFVTAFLSMWISNTAATAMMIPIVEAMLQQMiaantaveasl 207
Cdd:COG0471 1 LGGFVLAAALEKTGLGRRIALLLLKRFGGSPLRLLLGLMLATALLSAFISNTARAAMMLPIALSIAAAL----------- 69
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1732634002 208 gtlelldknktselpgsqvvfedpnvqeqEDEETKNMYKAMHLCVCYSASIGGTATLTGTGPNVVLLGQMQELFPDSkdv 287
Cdd:COG0471 70 -----------------------------GSEKRSKFGSALLLPIAFAASIGGMGTLIGTPPNLIAAGLLEEATGIP--- 117
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1732634002 288 LNYASWFGFAFPNMVMMLVLAWLWLqCLYMRHNLKKTciccgekkrdteKIAYKVLNEEYQKLGSLSYPECNVLFCFTLL 367
Cdd:COG0471 118 ISFFEWMLVGLPVALVGLLLLWLVL-YRLLPPEIKEV------------PGSKEVIREELAELGPLSRREKIALAIFALT 184
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1732634002 368 VILWFSRDPgfmpgwlsfawvegntVHITDATVAIFVAILLFIipsqkpkfnfssqteeerktpfypPALLDWKVAQEKV 447
Cdd:COG0471 185 VLLWITGSL----------------HGIPIAVVALLGAVLLLL------------------------TGVLTWKDAYKSI 224
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1732634002 448 PWDIVLLLGGGFAMAKGCETSGLSKWMAAQMEP-LRLVKPAVITLILSCLVAMTTECTSNVATTTLFLPIFASMARSIGI 526
Cdd:COG0471 225 PWGVLLLFGGGLALGAALEKTGLAAWLADALLPlLGGLSPLLLLLLLALLTLLLTEFASNTATAALLLPIAISLAQALGV 304
|
410 420 430 440 450 460
....*....|....*....|....*....|....*....|....*....|....*....|..
gi 1732634002 527 HPLYVMIPCTMSASLAFMLPVATPPNAIVFAYGHLRVVDMMKTGLIMNFVGILSVFLSVNTW 588
Cdd:COG0471 305 NPLPLALAVAFAASCAFLLPVGTPPNAIVYGSGYYKFKDFLKVGLPLNLIGLVVLLLLGPLW 366
|
|
| Na_sulph_symp |
pfam00939 |
Sodium:sulfate symporter transmembrane region; There are also some members in this family that ... |
50-595 |
1.60e-78 |
|
Sodium:sulfate symporter transmembrane region; There are also some members in this family that do not match the Prosite motif, and belong to the subfamily SODIT1.
Pssm-ID: 279307 [Multi-domain] Cd Length: 472 Bit Score: 256.53 E-value: 1.60e-78
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1732634002 50 SFAILLFTPILMLPLVILIPDKFARCAYVIVIMAVYWCTDVIPVAVTSLLPVLLFPLLKVLDSKQ----VCIQYMKDTNM 125
Cdd:pfam00939 8 LALLAVLLIILLLPAPDGLPSKAWHLFAIFIATIVGWILEPLPMAVIALFAISLSAILIGTLLAKalswALSGFSSTTTW 87
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1732634002 126 LFLGSLIVAVAVERWKLHKRVALRMLLFVGTKPsrLMLGFMFVTAFLSMWISNTAATAMMIPIVEAMLQQMIAANtavea 205
Cdd:pfam00939 88 LVFGAFFISAAFEKTGLGRRIALVLVKKMGKRT--LGLGYGLVFSDLLLAPATPSNTARAGGIVFPIIMSLPPAF----- 160
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1732634002 206 slgtlelldknktselpGSQVvfedpnvqeqEDEETKNMYKAMHLCVCYSASIGGTATLTGTGPNVVLLGQMQELfpdSK 285
Cdd:pfam00939 161 -----------------GSDP----------EKGSERRIGAYLMWTVYQSTSITSAMFLTAMAPNLLLLGLMNSI---LG 210
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1732634002 286 DVLNYASWFGFAFPNMVMMLVLAWLWLQCLYMrhnlkktciccGEKKRDTEkiAYKVLNEEYQKLGSLSYPECNVLFCFT 365
Cdd:pfam00939 211 VTITWASWFLAAIPPGVILLLLAPLLLYVLYP-----------PEIKSVPD--AKAIAKTELKELGPMTFREKALLGLFV 277
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1732634002 366 LLVILWFSrdpgfmpgwlsfawveGNTVHITDATVAIFVAILLFIIPsqkpkfnfssqteeerktpfyppaLLDWK-VAQ 444
Cdd:pfam00939 278 LLLLLWIF----------------GGSLNIDATTVAIIGLALMLLLR------------------------ILDWKdIVK 317
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1732634002 445 EKVPWDIVLLLGGGFAMAKGCETSGLSKWMAAQMEPL--RLVKPAVITLILSCLVAMTTECTSNVATTTLFLPIFASMAR 522
Cdd:pfam00939 318 NKGAWNTLIWLGGLIMLANGLERSGFIEWLGNTLSTSlsGFSPAMAFIIILSLFYLSHYLFASATAHTAAMLPIFAAVAQ 397
|
490 500 510 520 530 540 550
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 1732634002 523 SI-GIHPLYVMIPCTMSASLA-FMLPVATPPNAIVFAYGHLRVVDMMKTGLIMNFVGILSVFLSVNTWGRAMFNL 595
Cdd:pfam00939 398 AIpGAPPLLAALLLGFAISLGgFLTPYGTGPGPIYFGSGYLKVKDWWRIGAILTIIGLLILLLLGNWWWKPLGSL 472
|
|
| SLC13_permease |
cd01115 |
Permease SLC13 (solute carrier 13). The sodium/dicarboxylate cotransporter NaDC-1 has been ... |
76-585 |
5.77e-66 |
|
Permease SLC13 (solute carrier 13). The sodium/dicarboxylate cotransporter NaDC-1 has been shown to translocate Krebs cycle intermediates such as succinate, citrate, and alpha-ketoglutarate across plasma membranes rabbit, human, and rat kidney. It is related to renal and intestinal Na+/sulfate cotransporters and a few putative bacterial permeases. The SLC13-type proteins belong to the ArsB/NhaD superfamily of permeases that translocate sodium and various anions across biological membranes in all three kingdoms of life. A typical ArsB/NhaD permease is composed of 8-13 transmembrane helices.
Pssm-ID: 238535 [Multi-domain] Cd Length: 382 Bit Score: 220.53 E-value: 5.77e-66
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1732634002 76 AYVIVIMAVYWCTDVIPVAVTSLLPVLLFPLLKVLDSKQVCIQYMKDTNMLFLGSLIVAVAVERWKLHKRVALRMLLFVG 155
Cdd:cd01115 1 LAILVFAAVLFVTEALPLDVTALLVPVLLVLLGVVPPKEAFSGFSDPAVILFLAGFILGAALTRTGLAKRIATKLLKRAG 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1732634002 156 TKPSRLMLGFMFVTAFLSMWISNTAATAMMIPIVEAMLQQMIAANtaveaslgtlelldknktselpgsqvvfedpnvqe 235
Cdd:cd01115 81 KGERRLLLLLMLVTAFLSAFMSNTATVAIMLPVALGLAAKLDISP----------------------------------- 125
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1732634002 236 qedeetknmyKAMHLCVCYSASIGGTATLTGTGPNVVLLGQMQELFPDSkdvLNYASWFGFAFPNMVMMLVLAWLWLQcl 315
Cdd:cd01115 126 ----------SRLLMPLAFAASIGGMLTLIGTPPNLVASGYLESLGGQG---FSFFEFTPIGLPLLIIGLLYLWFIFR-- 190
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1732634002 316 ymrhnlkktciccgekkrdtekiaykvlneeyqklgslsypecNVLFCFTLLVILwfsrdpgfmpgwLSFAWVEGNTVHI 395
Cdd:cd01115 191 -------------------------------------------LAVLIITIVLLA------------ALAAITGLLPVSV 215
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1732634002 396 TDATVAIFVAILlfiipsqkpkfnfssqteeerktpfyppALLDWKVAQEKVPWDIVLLLGGGFAMAKGCETSGLSKWMA 475
Cdd:cd01115 216 AIAIGAIVLVFG----------------------------GVLLTKEDYKSIDWGIIFLFAGGIPLGKALESSGAAALIA 267
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1732634002 476 AQMEPLRLVKPAVITLILSCLVAMT-TECTSNVATTTLFLPIFASMARSIGIHPLYVMIPCTMSASLAFMLPVATPPNAI 554
Cdd:cd01115 268 EALISLLGGLPPFAILLLLCLLTLVlTNFISNTATAVLLAPIALSIALSLGLPPEALLLAVAIGASCAFMLPVGTPPNAI 347
|
490 500 510
....*....|....*....|....*....|.
gi 1732634002 555 VFAYGHLRVVDMMKTGLIMNfvgILSVFLSV 585
Cdd:cd01115 348 VLGPGGYKFSDFAKVGLPLS---ILSLVVSV 375
|
|
| dass |
TIGR00785 |
anion transporter; The Divalent Anion:Na+ Symporter (DASS) Family (TC 2.A.47) Functionally ... |
78-588 |
4.74e-46 |
|
anion transporter; The Divalent Anion:Na+ Symporter (DASS) Family (TC 2.A.47) Functionally characterized proteins of the DASS family transport (1) organic di- and tricarboxylates of the Krebs Cycle as well as dicarboxylate amino acid, (2) inorganic sulfate and (3) phosphate. The animal NaDC-1 cotransport 3 Na+ with each dicarboxylate. Protonated tricarboxylates are also cotransported with 3Na+. [Transport and binding proteins, Anions, Transport and binding proteins, Cations and iron carrying compounds]
Pssm-ID: 273267 [Multi-domain] Cd Length: 444 Bit Score: 168.68 E-value: 4.74e-46
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1732634002 78 VIVIMAVYWCTDVIPVAVTSLLPVLLFP----LLKVLDSKQVCIQYMKDTNMLFLGSLIVAVAVERWKLHKRVALRMLLF 153
Cdd:TIGR00785 16 IFVAAIVGWILEPLPLPVTALLAIPIIAvllgVLSAFKFKNALSGFADPTIWLFFGAFILATALVKTGLGKRIAYKLVGK 95
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1732634002 154 VGTKPSRL-MLGFMFVTAFLSMWISNTA-ATAMMIPIVEAMLQQMiaantaveaslgtlelldknktselpgsqvvfedp 231
Cdd:TIGR00785 96 MGGTTLGLgYFLVFLETLLAPMWPSNTArAGGILLPIIKSLLPLL----------------------------------- 140
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1732634002 232 nvQEQEDEETKNMYKAMHLCVCYSASIGGTATLTGTGPNVVLLGQMqelFPDSKDVLNYASWFGFAFPNMVMMLVLAWLW 311
Cdd:TIGR00785 141 --GSKPEKSPRKIGKYLMLGIAYSASIGSSGFLTGSAPNALAAGIL---SKILGIQISWGDWFLAGLPLGIILLLLVPLL 215
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1732634002 312 LQCLYmRHNLKKtciccgekKRDTEKIAykvlNEEYQKLGSLSYPEcnvlfcFTLLVILWFSRDPgfmpgwlsfaWVEGN 391
Cdd:TIGR00785 216 LYVLF-PPELKL--------KDEVDLWA----KEELEEMGPMSFRE------KALLGIFLLALLL----------WIFGG 266
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1732634002 392 TVHITDATVAIFVAILLFIIpsqkpkfnfssqteeerktpfyppALLDWK-VAQEKVPWDIVLLLGGGFAMAKGCETSGL 470
Cdd:TIGR00785 267 SLGINASVVALLAVVLMLFL------------------------GIVTWKdIQKNKVAWNTLILFGGLIGLAGGLKKSGF 322
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1732634002 471 SKWMAAQMEP--LRLVKPAVITLILSCLVAMTTECTSNVATTTLFLPIFASMARSIGIHPLYVMIPCTMSASLA-FMLPV 547
Cdd:TIGR00785 323 IKWFSEKLVGilDGLSPTIAVLVLVVLFYIILYFFASNTAHTAALVPIFFSVASAQGIPLELLALALALSASLMgFLTPY 402
|
490 500 510 520
....*....|....*....|....*....|....*....|.
gi 1732634002 548 ATPPNAIVFAYGHLRVVDMMKTGLIMNFVGILsVFLSVNTW 588
Cdd:TIGR00785 403 ATPPNAIAYGSGYVKIKDMWRVGAIIGIVGLI-VLLLVGTL 442
|
|
| ArsB_NhaD_permease |
cd00625 |
Anion permease ArsB/NhaD. These permeases have been shown to translocate sodium, arsenate, ... |
83-579 |
2.53e-36 |
|
Anion permease ArsB/NhaD. These permeases have been shown to translocate sodium, arsenate, antimonite, sulfate and organic anions across biological membranes in all three kingdoms of life. A typical anion permease contains 8-13 transmembrane helices and can function either independently as a chemiosmotic transporter or as a channel-forming subunit of an ATP-driven anion pump.
Pssm-ID: 238344 [Multi-domain] Cd Length: 396 Bit Score: 140.46 E-value: 2.53e-36
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1732634002 83 AVYWCTDVIPVAVTSLLPVLLFPLLKVLDSKQVCIQYMKDTNMLFLGSLIVAVAVERWKLHKRVALRMLLFvGTKPSRLM 162
Cdd:cd00625 1 YVLIRPEKLPRAVVALLGAVLLVLLGVVSPKEALSAIDWETILLLFGMMILSAALEETGLFDRLAAKLARA-SKGSRRLL 79
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1732634002 163 LGFMFVTAFLSMWISNTAATAMMIPIVEAMLQQMIAANTaveaslgtlelldknktselpgsqvvfedpnvqeqedeetk 242
Cdd:cd00625 80 LLLMLLTAALSAFFSNDATAVLLTPIVLALLRKLGLSPP----------------------------------------- 118
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1732634002 243 nmyKAMHLCVCYSASIGGTATLTGTGPNVVLLGQMQelfpdskdvLNYASWFGFAFPNMVMMLVLAWLWLQCLYMRHNLK 322
Cdd:cd00625 119 ---VPLLLALAFAANIGGAATPIGNPPNLIIASLSG---------LGFLDFLAFMAPPALGLLLLLLGLLYLLFRKKLLL 186
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1732634002 323 KtciccgekKRDTEKIAYKVLNEEYQKLGSLSYpecnVLFCFTLLVILWFSrdpGFMPGWlsfawvegntvhITDATVAI 402
Cdd:cd00625 187 P--------DEDKLTVLAEPLPARPLLKKFLLL----ALLLLLLFVLLFFF---LIPLGL------------IALLGALL 239
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1732634002 403 FVAILLFIipsqkpkfnfssqteeerktpfyppalLDWKVAQEKVPWDIVLLLGGGFAMAKGCETSGLSKWMAAQMEPLR 482
Cdd:cd00625 240 LLLLLVRG---------------------------LDPEEVLKSVDWGTLLFFAGLFVLVGALESTGLLEWLAELLVALV 292
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1732634002 483 LVKPAVITLILSCLVAMTTECTSNVATTTLFLPIFASMAR-----SIGIHPLYVMIPCTMSASLAFMLPVATPPNAIVfa 557
Cdd:cd00625 293 GLPPLAALLLIGLLSALLSNFISNVPTVALLLPIAASLAPpepawLALALGSTLGGNLTLIGSLANLIPLGAAENAGV-- 370
|
490 500
....*....|....*....|..
gi 1732634002 558 ygHLRVVDMMKTGLIMNFVGIL 579
Cdd:cd00625 371 --GISFGEFLKVGLPLTLLSLV 390
|
|
| CitMHS |
pfam03600 |
Citrate transporter; |
83-533 |
1.43e-23 |
|
Citrate transporter;
Pssm-ID: 460985 [Multi-domain] Cd Length: 342 Bit Score: 102.39 E-value: 1.43e-23
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1732634002 83 AVYWCTDVIPVAVTSLLPVLLFPLLKVLDSKQVCIQYMKDTNMLFLGSLIVAVAVERWKLHKRVALRMLLFVGTKPSRLM 162
Cdd:pfam03600 1 YVLIITEKLPRDVVALLGAVLLVLLGVLTPEEALSGIDSPTILLLLGMMIIGAILERTGLFDRLALKLLRLAGGKPRRLL 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1732634002 163 LGFMFVTAFLSMWISNTAATAMMIPIVeamlqqmiaantaveaslgtLELLDKNKTSELPgsqvvfedpnvqeqedeetk 242
Cdd:pfam03600 81 VALMLATALLSAFLSNDGTVLIMIPIV--------------------LALARRLGLPPSP-------------------- 120
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1732634002 243 nmykaMHLCVCYSASIGGTATLTGTGPNVVLLGQMQELFPDskdvlnyaswFGFAFPNMVMMLVLAWLWLQCLYMRHNLK 322
Cdd:pfam03600 121 -----LLIALAFAANIGGTATPIGDPPNIIIASALGLSFGD----------FGFFMFPPVGVALLLVGLLPLLLIFRKLL 185
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1732634002 323 KTCICCGEKKRDTEKIAYKVLneeyqklgslsypecnVLFCFTLLVILwfsrdpgfmpgwlsfAWVEGNTVHITDATVAI 402
Cdd:pfam03600 186 PVRKEEEAELEELRKRAIKDK----------------LLLAISALVLA---------------LVILGFLLLSVLALAGA 234
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1732634002 403 FVAILLFIIpsqkpkfnfssqteeerktpfyppallDWKVAQEKVPWDIVLLLGGGFAMAKGCETSGLSKWMAAQMEPlr 482
Cdd:pfam03600 235 LLLLLTGVL---------------------------DPEEALKAVDWSTLLFFAGLFILVGALEKTGLADALADALGG-- 285
|
410 420 430 440 450
....*....|....*....|....*....|....*....|....*....|.
gi 1732634002 483 LVKPAVITLILSCLVAMTTECTSNVATTTLFLPIFASMARSIGIHPLYVMI 533
Cdd:pfam03600 286 LSGLLVALALILWLSALLSAFISNVPTAALMAPIIVGMAPAAGLGDPDPLA 336
|
|
| CitMHS |
pfam03600 |
Citrate transporter; |
434-583 |
4.43e-10 |
|
Citrate transporter;
Pssm-ID: 460985 [Multi-domain] Cd Length: 342 Bit Score: 61.56 E-value: 4.43e-10
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1732634002 434 PPALLDWKVAQEKVPWDIVLLLGGGFAMAKGCETSGLSKWMAAQMepLRLVK--PAVITLILSCLVAMTTECTSNVATTT 511
Cdd:pfam03600 24 LLGVLTPEEALSGIDSPTILLLLGMMIIGAILERTGLFDRLALKL--LRLAGgkPRRLLVALMLATALLSAFLSNDGTVL 101
|
90 100 110 120 130 140 150
....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 1732634002 512 LFLPIFASMARSIGIHPLYVMIPCTMSASLAFML-PVATPPNAIVFAYGHLRVVDMMKTGLIMNFVGILSVFL 583
Cdd:pfam03600 102 IMIPIVLALARRLGLPPSPLLIALAFAANIGGTAtPIGDPPNIIIASALGLSFGDFGFFMFPPVGVALLLVGL 174
|
|
| ArsB_NhaD_permease |
cd00625 |
Anion permease ArsB/NhaD. These permeases have been shown to translocate sodium, arsenate, ... |
449-583 |
9.79e-10 |
|
Anion permease ArsB/NhaD. These permeases have been shown to translocate sodium, arsenate, antimonite, sulfate and organic anions across biological membranes in all three kingdoms of life. A typical anion permease contains 8-13 transmembrane helices and can function either independently as a chemiosmotic transporter or as a channel-forming subunit of an ATP-driven anion pump.
Pssm-ID: 238344 [Multi-domain] Cd Length: 396 Bit Score: 60.73 E-value: 9.79e-10
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1732634002 449 WDIVLLLGGGFAMAKGCETSGLSKWMAAQMEpLRLVKPAVITLILSCLVAMTTECTSNVATTTLFLPIFASMARSIGI-H 527
Cdd:cd00625 39 WETILLLFGMMILSAALEETGLFDRLAAKLA-RASKGSRRLLLLLMLLTAALSAFFSNDATAVLLTPIVLALLRKLGLsP 117
|
90 100 110 120 130
....*....|....*....|....*....|....*....|....*....|....*..
gi 1732634002 528 PLYVMIPCTMSASLA-FMLPVATPPNAIVFAYGHLRVVDMMKTGLIMNFVGILSVFL 583
Cdd:cd00625 118 PVPLLLALAFAANIGgAATPIGNPPNLIIASLSGLGFLDFLAFMAPPALGLLLLLLG 174
|
|
| ArsB |
COG1055 |
Na+/H+ antiporter NhaD or related arsenite permease [Inorganic ion transport and metabolism]; |
398-583 |
3.68e-07 |
|
Na+/H+ antiporter NhaD or related arsenite permease [Inorganic ion transport and metabolism];
Pssm-ID: 440675 [Multi-domain] Cd Length: 415 Bit Score: 52.82 E-value: 3.68e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1732634002 398 ATVAIFVAILLFIIpSQKPKFNFSSqteeerktpfypPALL-----------DWKVAQEKVPWDIVLLLGGGFAMAKGCE 466
Cdd:COG1055 4 LALAIFVLTYLLII-LEPRGLNRAV------------AALLgaalllllgvvSLEDALEAIDWNTILFLLGMMIIVAILD 70
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1732634002 467 TSGLSKWMAAQMEPLRLVKPAVITLILSCLVAMTTECTSNVATTTLFLPIFASMARSIGIHPLYVMIPCTMSASLA-FML 545
Cdd:COG1055 71 ESGFFEWLAIKLARRAKGSPRRLLWLLGLLTALLSAFLDNDTTALLLTPVVLAIARRLGLNPVPFLIAIVFAANIGgAAT 150
|
170 180 190
....*....|....*....|....*....|....*...
gi 1732634002 546 PVATPPNAIVFAYGHLRVVDMMKTGLIMNFVGILSVFL 583
Cdd:COG1055 151 PIGNPTNIMIASAGGLSFLDFLANLFPPSLVSLLVTLL 188
|
|
| ArsB |
COG1055 |
Na+/H+ antiporter NhaD or related arsenite permease [Inorganic ion transport and metabolism]; |
122-579 |
9.96e-07 |
|
Na+/H+ antiporter NhaD or related arsenite permease [Inorganic ion transport and metabolism];
Pssm-ID: 440675 [Multi-domain] Cd Length: 415 Bit Score: 51.28 E-value: 9.96e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1732634002 122 DTNMLFLGSLIVAVAVERWKLHKRVALRMLLFVGTKPSRLMLGFMFVTAFLSMWISNTAATAMMIPIVEAMLQQM----- 196
Cdd:COG1055 54 NTILFLLGMMIIVAILDESGFFEWLAIKLARRAKGSPRRLLWLLGLLTALLSAFLDNDTTALLLTPVVLAIARRLglnpv 133
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1732634002 197 -------IAANTAveaSLGTLelldknktselpgsqvvFEDPnvqeqedeetknmykamhlcvcysasiggtatltgtgP 269
Cdd:COG1055 134 pfliaivFAANIG---GAATP-----------------IGNP-------------------------------------T 156
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1732634002 270 NVVLLGQMQelfpdskdvLNYASWFGFAFPNMVMMLVLAWLWLqCLYMRHNLKKTCIccgEKKRDTEKIAYKVLneeyqk 349
Cdd:COG1055 157 NIMIASAGG---------LSFLDFLANLFPPSLVSLLVTLLVL-YLLFRKELPAAPD---LEDDPKEAIKDRRL------ 217
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1732634002 350 lgslsypeCNVLFCFTLLVILWFsrdpgfmpgwlsfawVEGNTVHITDATVAIFVAILLFIIpsqkpkfnfssqteeerk 429
Cdd:COG1055 218 --------LRISLLVLALLLVGF---------------VLHSFLGLPPALIALLGAAVLLLL------------------ 256
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1732634002 430 TPFYPPALLdwkvaqEKVPWDIVLLLGGGFAMAKGCETSGLSKWMAAQMEPLRLVKPAVITLILSCLVAMTTECTSNVAT 509
Cdd:COG1055 257 ARVDVREVL------KKVDWSTLLFFIGLFVVVGGLENTGLLDLLAELLASLTGGNLLLAALLILWLSAILSAVVDNVPL 330
|
410 420 430 440 450 460 470
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 1732634002 510 TTLFLPIFASMARSIGIHPLYVMIpcTMSASLA-FMLPVATPPNAIVF-----AYGHLRVVDMMKTGLIMNFVGIL 579
Cdd:COG1055 331 VAALLPLIPDLGATGNPEPLWLAL--ALGATLGgNLTPIGSAANVIVLgiaekKGIKISFGEFLKVGLPLTLLTLL 404
|
|
| CitMHS |
pfam03600 |
Citrate transporter; |
48-200 |
1.75e-05 |
|
Citrate transporter;
Pssm-ID: 460985 [Multi-domain] Cd Length: 342 Bit Score: 47.31 E-value: 1.75e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1732634002 48 FKSFAILLFTPILMLPLVILIPDKFARCAYVIVIMAVYWCTDVIPVAVTSLLPVLLFPLLKVLDSKQVCIQYMKDTNMLF 127
Cdd:pfam03600 181 FRKLLPVRKEEEAELEELRKRAIKDKLLLAISALVLALVILGFLLLSVLALAGALLLLLTGVLDPEEALKAVDWSTLLFF 260
|
90 100 110 120 130 140 150
....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 1732634002 128 LGSLIVAVAVERWKLHKRVALRMLLFVGtkPSRLMLGFMFVTAFLSMWISNTAATAMMIPIVEAMLQQMIAAN 200
Cdd:pfam03600 261 AGLFILVGALEKTGLADALADALGGLSG--LLVALALILWLSALLSAFISNVPTAALMAPIIVGMAPAAGLGD 331
|
|
| SLC13_permease |
cd01115 |
Permease SLC13 (solute carrier 13). The sodium/dicarboxylate cotransporter NaDC-1 has been ... |
48-203 |
5.09e-05 |
|
Permease SLC13 (solute carrier 13). The sodium/dicarboxylate cotransporter NaDC-1 has been shown to translocate Krebs cycle intermediates such as succinate, citrate, and alpha-ketoglutarate across plasma membranes rabbit, human, and rat kidney. It is related to renal and intestinal Na+/sulfate cotransporters and a few putative bacterial permeases. The SLC13-type proteins belong to the ArsB/NhaD superfamily of permeases that translocate sodium and various anions across biological membranes in all three kingdoms of life. A typical ArsB/NhaD permease is composed of 8-13 transmembrane helices.
Pssm-ID: 238535 [Multi-domain] Cd Length: 382 Bit Score: 46.04 E-value: 5.09e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1732634002 48 FKSFAILLFTPILMLPLVILIP---DKFARCAYVIVIMAvyWC-----TDVIPVAVTSLLPVLLFPLLKVLDSKQVCIQY 119
Cdd:cd01115 162 GQGFSFFEFTPIGLPLLIIGLLylwFIFRLAVLIITIVL--LAalaaiTGLLPVSVAIAIGAIVLVFGGVLLTKEDYKSI 239
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1732634002 120 MKDTNMLFLGSLIVAVAVERWKLHKRVAlRMLLFVGTK--PSRLMLGFMFVTAFLSMWISNTAATAMMIPIVEAMLQQMI 197
Cdd:cd01115 240 DWGIIFLFAGGIPLGKALESSGAAALIA-EALISLLGGlpPFAILLLLCLLTLVLTNFISNTATAVLLAPIALSIALSLG 318
|
....*.
gi 1732634002 198 AANTAV 203
Cdd:cd01115 319 LPPEAL 324
|
|
| CitT |
COG0471 |
Di- and tricarboxylate antiporter [Carbohydrate transport and metabolism]; |
78-196 |
1.33e-03 |
|
Di- and tricarboxylate antiporter [Carbohydrate transport and metabolism];
Pssm-ID: 440239 [Multi-domain] Cd Length: 369 Bit Score: 41.29 E-value: 1.33e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1732634002 78 VIVIMAVYWCTD---VIPVAVTSLLPVLLFPLLKVLDSKQvcIQYMKDTNMLFL--GSLIVAVAVERWKLHKRVALRMLL 152
Cdd:COG0471 180 IFALTVLLWITGslhGIPIAVVALLGAVLLLLTGVLTWKD--AYKSIPWGVLLLfgGGLALGAALEKTGLAAWLADALLP 257
|
90 100 110 120
....*....|....*....|....*....|....*....|....*
gi 1732634002 153 FVGTKPSRLML-GFMFVTAFLSMWISNTAATAMMIPIVEAMLQQM 196
Cdd:COG0471 258 LLGGLSPLLLLlLLALLTLLLTEFASNTATAALLLPIAISLAQAL 302
|
|
| |
