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Conserved domains on  [gi|1820048647|ref|NP_001365697|]
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SLIT and NTRK-like protein 5 isoform 2 [Mus musculus]

Protein Classification

SLIT and NTRK-like protein 5( domain architecture ID 17599378)

SLIT and NTRK-like protein 5 (SLITRK5) suppresses neurite outgrowth

Gene Symbol:  SLITRK5
Gene Ontology:  GO:0005515|GO:0007409
PubMed:  14747988|11751054

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
LRR COG4886
Leucine-rich repeat (LRR) protein [Transcription];
111-260 2.41e-20

Leucine-rich repeat (LRR) protein [Transcription];


:

Pssm-ID: 443914 [Multi-domain]  Cd Length: 414  Bit Score: 95.00  E-value: 2.41e-20
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1820048647 111 LLLSGNLLSRLyPNEFVNYTGASILHLGSNVIQDIETgAFHGLRGLRRLHLNNNKLELLrDDTFLGLENLEYLQVDYNYI 190
Cdd:COG4886   118 LDLSGNQLTDL-PEELANLTNLKELDLSNNQLTDLPE-PLGNLTNLKSLDLSNNQLTDL-PEELGNLTNLKELDLSNNQI 194

                          90       100       110       120       130       140       150
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1820048647 191 SVIePNAFGKLHMLQVLILNDNLLSGLPNNLFRFVPLTHLDLRGNRLKLLPYvglLQHMDKVVELQLEEN 260
Cdd:COG4886   195 TDL-PEPLGNLTNLEELDLSGNQLTDLPEPLANLTNLETLDLSNNQLTDLPE---LGNLTNLEELDLSNN 260
LRR_8 pfam13855
Leucine rich repeat;
458-518 6.71e-15

Leucine rich repeat;


:

Pssm-ID: 404697 [Multi-domain]  Cd Length: 61  Bit Score: 69.86  E-value: 6.71e-15
                          10        20        30        40        50        60
                  ....*....|....*....|....*....|....*....|....*....|....*....|.
gi 1820048647 458 TGLDLLHLGNNRISMIQDRAFGDLGNLRRLYLNGNRIERLSPELFYGLQSLQYLFLQYNLI 518
Cdd:pfam13855   1 PNLRSLDLSNNRLTSLDDGAFKGLSNLKVLDLSNNLLTTLSPGAFSGLPSLRYLDLSGNRL 61
PPP1R42 super family cl42388
protein phosphatase 1 regulatory subunit 42; Protein phosphatase 1 regulatory subunit 42 ...
 416-588 9.68e-12

protein phosphatase 1 regulatory subunit 42; Protein phosphatase 1 regulatory subunit 42 (PPP1R42), also known as leucine-rich repeat-containing protein 67 (lrrc67) or testis leucine-rich repeat (TLRR) protein, plays a role in centrosome separation. PPP1R42 has been shown to interact with the well-conserved signaling protein phosphatase-1 (PP1) and thereby increasing PP1's activity, which counters centrosome separation. Inhibition of PPP1R42 expression increases the number of centrosomes per cell while its depletion reduces the activity of PP1 leading to activation of NEK2, the kinase responsible for phosphorylation of centrosomal linker proteins promoting centrosome separation.


The actual alignment was detected with superfamily member cd21340:

Pssm-ID: 455733 [Multi-domain]  Cd Length: 220  Bit Score: 65.58  E-value: 9.68e-12
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1820048647 416 VNCQERKIESIAELQPKPyNPKKMYLTENYITVVRRTDFLeaTGLDLLHLGNNRISMIQDraFGDLGNLRRLYLNGNRIE 495
Cdd:cd21340     7 LYLNDKNITKIDNLSLCK-NLKVLYLYDNKITKIENLEFL--TNLTHLYLQNNQIEKIEN--LENLVNLKKLYLGGNRIS 81

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1820048647 496 RLspELFYGLQSLQYLFLQYNLIREIQAGTFDPvpnlqllflnnnqlqampsgvFSGLTLLR----LNLRGNSFTSLpvs 571
Cdd:cd21340    82 VV--EGLENLTNLEELHIENQRLPPGEKLTFDP---------------------RSLAALSNslrvLNISGNNIDSL--- 135

                         170
                  ....*....|....*..
gi 1820048647 572 GVLDQLTSLIQIDLHDN 588
Cdd:cd21340   136 EPLAPLRNLEQLDASNN 152
LRRCT smart00082
Leucine rich repeat C-terminal domain;
260-298 1.21e-06

Leucine rich repeat C-terminal domain;


:

Pssm-ID: 214507 [Multi-domain]  Cd Length: 51  Bit Score: 46.27  E-value: 1.21e-06
                           10        20        30
                   ....*....|....*....|....*....|....*....
gi 1820048647  260 NPWNCSCELISLKDWLDSISYSALVGDVVCETPFRLHGR 298
Cdd:smart00082   1 NPFICDCELRWLLRWLQANEHLQDPVDLRCASPSSLRGP 39
LRRCT super family cl47026
Leucine rich repeat C-terminal domain;
588-624 2.98e-03

Leucine rich repeat C-terminal domain;


The actual alignment was detected with superfamily member smart00082:

Pssm-ID: 214507 [Multi-domain]  Cd Length: 51  Bit Score: 36.64  E-value: 2.98e-03
                           10        20        30
                   ....*....|....*....|....*....|....*..
gi 1820048647  588 NPWDCTCDVVGMKLWIEQLKVGVLVDEVICKAPKKFA 624
Cdd:smart00082   1 NPFICDCELRWLLRWLQANEHLQDPVDLRCASPSSLR 37
 
Name Accession Description Interval E-value
LRR COG4886
Leucine-rich repeat (LRR) protein [Transcription];
111-260 2.41e-20

Leucine-rich repeat (LRR) protein [Transcription];


Pssm-ID: 443914 [Multi-domain]  Cd Length: 414  Bit Score: 95.00  E-value: 2.41e-20
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1820048647 111 LLLSGNLLSRLyPNEFVNYTGASILHLGSNVIQDIETgAFHGLRGLRRLHLNNNKLELLrDDTFLGLENLEYLQVDYNYI 190
Cdd:COG4886   118 LDLSGNQLTDL-PEELANLTNLKELDLSNNQLTDLPE-PLGNLTNLKSLDLSNNQLTDL-PEELGNLTNLKELDLSNNQI 194

                          90       100       110       120       130       140       150
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1820048647 191 SVIePNAFGKLHMLQVLILNDNLLSGLPNNLFRFVPLTHLDLRGNRLKLLPYvglLQHMDKVVELQLEEN 260
Cdd:COG4886   195 TDL-PEPLGNLTNLEELDLSGNQLTDLPEPLANLTNLETLDLSNNQLTDLPE---LGNLTNLEELDLSNN 260
LRR_8 pfam13855
Leucine rich repeat;
154-214 3.20e-15

Leucine rich repeat;


Pssm-ID: 404697 [Multi-domain]  Cd Length: 61  Bit Score: 70.63  E-value: 3.20e-15
                          10        20        30        40        50        60
                  ....*....|....*....|....*....|....*....|....*....|....*....|.
gi 1820048647 154 RGLRRLHLNNNKLELLRDDTFLGLENLEYLQVDYNYISVIEPNAFGKLHMLQVLILNDNLL 214
Cdd:pfam13855   1 PNLRSLDLSNNRLTSLDDGAFKGLSNLKVLDLSNNLLTTLSPGAFSGLPSLRYLDLSGNRL 61
LRR_8 pfam13855
Leucine rich repeat;
458-518 6.71e-15

Leucine rich repeat;


Pssm-ID: 404697 [Multi-domain]  Cd Length: 61  Bit Score: 69.86  E-value: 6.71e-15
                          10        20        30        40        50        60
                  ....*....|....*....|....*....|....*....|....*....|....*....|.
gi 1820048647 458 TGLDLLHLGNNRISMIQDRAFGDLGNLRRLYLNGNRIERLSPELFYGLQSLQYLFLQYNLI 518
Cdd:pfam13855   1 PNLRSLDLSNNRLTSLDDGAFKGLSNLKVLDLSNNLLTTLSPGAFSGLPSLRYLDLSGNRL 61
PPP1R42 cd21340
protein phosphatase 1 regulatory subunit 42; Protein phosphatase 1 regulatory subunit 42 ...
 416-588 9.68e-12

protein phosphatase 1 regulatory subunit 42; Protein phosphatase 1 regulatory subunit 42 (PPP1R42), also known as leucine-rich repeat-containing protein 67 (lrrc67) or testis leucine-rich repeat (TLRR) protein, plays a role in centrosome separation. PPP1R42 has been shown to interact with the well-conserved signaling protein phosphatase-1 (PP1) and thereby increasing PP1's activity, which counters centrosome separation. Inhibition of PPP1R42 expression increases the number of centrosomes per cell while its depletion reduces the activity of PP1 leading to activation of NEK2, the kinase responsible for phosphorylation of centrosomal linker proteins promoting centrosome separation.


Pssm-ID: 411060 [Multi-domain]  Cd Length: 220  Bit Score: 65.58  E-value: 9.68e-12
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1820048647 416 VNCQERKIESIAELQPKPyNPKKMYLTENYITVVRRTDFLeaTGLDLLHLGNNRISMIQDraFGDLGNLRRLYLNGNRIE 495
Cdd:cd21340     7 LYLNDKNITKIDNLSLCK-NLKVLYLYDNKITKIENLEFL--TNLTHLYLQNNQIEKIEN--LENLVNLKKLYLGGNRIS 81

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1820048647 496 RLspELFYGLQSLQYLFLQYNLIREIQAGTFDPvpnlqllflnnnqlqampsgvFSGLTLLR----LNLRGNSFTSLpvs 571
Cdd:cd21340    82 VV--EGLENLTNLEELHIENQRLPPGEKLTFDP---------------------RSLAALSNslrvLNISGNNIDSL--- 135

                         170
                  ....*....|....*..
gi 1820048647 572 GVLDQLTSLIQIDLHDN 588
Cdd:cd21340   136 EPLAPLRNLEQLDASNN 152
LRR COG4886
Leucine-rich repeat (LRR) protein [Transcription];
452-588 9.43e-10

Leucine-rich repeat (LRR) protein [Transcription];


Pssm-ID: 443914 [Multi-domain]  Cd Length: 414  Bit Score: 61.87  E-value: 9.43e-10
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1820048647 452 TDFLEATGLDLLHLGNNRISMIqDRAFGDLGNLRRLYLNGNRIERLSPELFyGLQSLQYLFLQYNLIREIQAGtFDPVPN 531
Cdd:COG4886   107 EELSNLTNLESLDLSGNQLTDL-PEELANLTNLKELDLSNNQLTDLPEPLG-NLTNLKSLDLSNNQLTDLPEE-LGNLTN 183

                          90       100       110       120       130
                  ....*....|....*....|....*....|....*....|....*....|....*...
gi 1820048647 532 LQLLFLNNNQLQAMPSgVFSGLTLLR-LNLRGNSFTSLPVSgvLDQLTSLIQIDLHDN 588
Cdd:COG4886   184 LKELDLSNNQITDLPE-PLGNLTNLEeLDLSGNQLTDLPEP--LANLTNLETLDLSNN 238
PPP1R42 cd21340
protein phosphatase 1 regulatory subunit 42; Protein phosphatase 1 regulatory subunit 42 ...
 110-260 5.94e-08

protein phosphatase 1 regulatory subunit 42; Protein phosphatase 1 regulatory subunit 42 (PPP1R42), also known as leucine-rich repeat-containing protein 67 (lrrc67) or testis leucine-rich repeat (TLRR) protein, plays a role in centrosome separation. PPP1R42 has been shown to interact with the well-conserved signaling protein phosphatase-1 (PP1) and thereby increasing PP1's activity, which counters centrosome separation. Inhibition of PPP1R42 expression increases the number of centrosomes per cell while its depletion reduces the activity of PP1 leading to activation of NEK2, the kinase responsible for phosphorylation of centrosomal linker proteins promoting centrosome separation.


Pssm-ID: 411060 [Multi-domain]  Cd Length: 220  Bit Score: 54.41  E-value: 5.94e-08
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1820048647 110 HLLLSGNLLSRLypNEFVNYTGASILHLGSNVIQDIEtgAFHGLRGLRRLHLNNNKLELLRDdtFLGLENLEYLQVDYNY 189
Cdd:cd21340     6 HLYLNDKNITKI--DNLSLCKNLKVLYLYDNKITKIE--NLEFLTNLTHLYLQNNQIEKIEN--LENLVNLKKLYLGGNR 79

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1820048647 190 ISVIEpnAFGKLHMLQVL-ILNDNLLSGLPnnlFRFVP---------LTHLDLRGNRlklLPYVGLLQHMDKVVELQLEE 259
Cdd:cd21340    80 ISVVE--GLENLTNLEELhIENQRLPPGEK---LTFDPrslaalsnsLRVLNISGNN---IDSLEPLAPLRNLEQLDASN 151


                  .
gi 1820048647 260 N 260
Cdd:cd21340   152 N 152
LRRCT smart00082
Leucine rich repeat C-terminal domain;
260-298 1.21e-06

Leucine rich repeat C-terminal domain;


Pssm-ID: 214507 [Multi-domain]  Cd Length: 51  Bit Score: 46.27  E-value: 1.21e-06
                           10        20        30
                   ....*....|....*....|....*....|....*....
gi 1820048647  260 NPWNCSCELISLKDWLDSISYSALVGDVVCETPFRLHGR 298
Cdd:smart00082   1 NPFICDCELRWLLRWLQANEHLQDPVDLRCASPSSLRGP 39
PLN00113 PLN00113
leucine-rich repeat receptor-like protein kinase; Provisional
 111-237 1.86e-05

leucine-rich repeat receptor-like protein kinase; Provisional


Pssm-ID: 215061 [Multi-domain]  Cd Length: 968  Bit Score: 48.69  E-value: 1.86e-05
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1820048647 111 LLLSGNLLSRLYPNEFVNYTGASILHLGSNVIQDIETGAFHGLRGLRRLHLNNNKLELLRDDTFLGLENLEYLQVDYNYI 190
Cdd:PLN00113  169 LDLGGNVLVGKIPNSLTNLTSLEFLTLASNQLVGQIPRELGQMKSLKWIYLGYNNLSGEIPYEIGGLTSLNHLDLVYNNL 248

                          90       100       110       120
                  ....*....|....*....|....*....|....*....|....*...
gi 1820048647 191 SVIEPNAFGKLHMLQVLILNDNLLSG-LPNNLFRFVPLTHLDLRGNRL 237
Cdd:PLN00113  249 TGPIPSSLGNLKNLQYLFLYQNKLSGpIPPSIFSLQKLISLDLSDNSL 296
RNA1 COG5238
Ran GTPase-activating protein (RanGAP) involved in mRNA processing and transport [Translation, ...
 406-520 1.14e-03

Ran GTPase-activating protein (RanGAP) involved in mRNA processing and transport [Translation, ribosomal structure and biogenesis];


Pssm-ID: 444072 [Multi-domain]  Cd Length: 434  Bit Score: 42.47  E-value: 1.14e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1820048647 406 NLQISDLGLNvNCQERKIESIAELQPKPYNPKKMYLTENYITVVRRTDFLEA----TGLDLLHLGNNRISmiqDRAFGDL 481
Cdd:COG5238   181 SVETVYLGCN-QIGDEGIEELAEALTQNTTVTTLWLKRNPIGDEGAEILAEAlkgnKSLTTLDLSNNQIG---DEGVIAL 256

                          90       100       110       120       130
                  ....*....|....*....|....*....|....*....|....*....|
gi 1820048647 482 G-------NLRRLYLNGNRIE----RLSPELFYGLQSLQYLFLQYNLIRE 520
Cdd:COG5238   257 AealknntTVETLYLSGNQIGaegaIALAKALQGNTTLTSLDLSVNRIGD 306
LRRCT smart00082
Leucine rich repeat C-terminal domain;
588-624 2.98e-03

Leucine rich repeat C-terminal domain;


Pssm-ID: 214507 [Multi-domain]  Cd Length: 51  Bit Score: 36.64  E-value: 2.98e-03
                           10        20        30
                   ....*....|....*....|....*....|....*..
gi 1820048647  588 NPWDCTCDVVGMKLWIEQLKVGVLVDEVICKAPKKFA 624
Cdd:smart00082   1 NPFICDCELRWLLRWLQANEHLQDPVDLRCASPSSLR 37
LRR smart00370
Leucine-rich repeats, outliers;
481-504 4.33e-03

Leucine-rich repeats, outliers;


Pssm-ID: 197688 [Multi-domain]  Cd Length: 24  Bit Score: 35.41  E-value: 4.33e-03
                           10        20
                   ....*....|....*....|....
gi 1820048647  481 LGNLRRLYLNGNRIERLSPELFYG 504
Cdd:smart00370   1 LPNLRELDLSNNQLSSLPPGAFQG 24
 
Name Accession Description Interval E-value
LRR COG4886
Leucine-rich repeat (LRR) protein [Transcription];
111-260 2.41e-20

Leucine-rich repeat (LRR) protein [Transcription];


Pssm-ID: 443914 [Multi-domain]  Cd Length: 414  Bit Score: 95.00  E-value: 2.41e-20
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1820048647 111 LLLSGNLLSRLyPNEFVNYTGASILHLGSNVIQDIETgAFHGLRGLRRLHLNNNKLELLrDDTFLGLENLEYLQVDYNYI 190
Cdd:COG4886   118 LDLSGNQLTDL-PEELANLTNLKELDLSNNQLTDLPE-PLGNLTNLKSLDLSNNQLTDL-PEELGNLTNLKELDLSNNQI 194

                          90       100       110       120       130       140       150
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1820048647 191 SVIePNAFGKLHMLQVLILNDNLLSGLPNNLFRFVPLTHLDLRGNRLKLLPYvglLQHMDKVVELQLEEN 260
Cdd:COG4886   195 TDL-PEPLGNLTNLEELDLSGNQLTDLPEPLANLTNLETLDLSNNQLTDLPE---LGNLTNLEELDLSNN 260
LRR COG4886
Leucine-rich repeat (LRR) protein [Transcription];
110-261 1.68e-17

Leucine-rich repeat (LRR) protein [Transcription];


Pssm-ID: 443914 [Multi-domain]  Cd Length: 414  Bit Score: 86.14  E-value: 1.68e-17
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1820048647 110 HLLLSGNLLSRLyPNEFVNYTGASILHLGSNVIQDIeTGAFHGLRGLRRLHLNNNKLELLrDDTFLGLENLEYLQVDYNY 189
Cdd:COG4886   140 ELDLSNNQLTDL-PEPLGNLTNLKSLDLSNNQLTDL-PEELGNLTNLKELDLSNNQITDL-PEPLGNLTNLEELDLSGNQ 216

                          90       100       110       120       130       140       150
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 1820048647 190 ISVIePNAFGKLHMLQVLILNDNLLSGLPNnLFRFVPLTHLDLRGNRLKLLPyvgLLQHMDKVVELQLEENP 261
Cdd:COG4886   217 LTDL-PEPLANLTNLETLDLSNNQLTDLPE-LGNLTNLEELDLSNNQLTDLP---PLANLTNLKTLDLSNNQ 283
LRR_8 pfam13855
Leucine rich repeat;
154-214 3.20e-15

Leucine rich repeat;


Pssm-ID: 404697 [Multi-domain]  Cd Length: 61  Bit Score: 70.63  E-value: 3.20e-15
                          10        20        30        40        50        60
                  ....*....|....*....|....*....|....*....|....*....|....*....|.
gi 1820048647 154 RGLRRLHLNNNKLELLRDDTFLGLENLEYLQVDYNYISVIEPNAFGKLHMLQVLILNDNLL 214
Cdd:pfam13855   1 PNLRSLDLSNNRLTSLDDGAFKGLSNLKVLDLSNNLLTTLSPGAFSGLPSLRYLDLSGNRL 61
LRR_8 pfam13855
Leucine rich repeat;
458-518 6.71e-15

Leucine rich repeat;


Pssm-ID: 404697 [Multi-domain]  Cd Length: 61  Bit Score: 69.86  E-value: 6.71e-15
                          10        20        30        40        50        60
                  ....*....|....*....|....*....|....*....|....*....|....*....|.
gi 1820048647 458 TGLDLLHLGNNRISMIQDRAFGDLGNLRRLYLNGNRIERLSPELFYGLQSLQYLFLQYNLI 518
Cdd:pfam13855   1 PNLRSLDLSNNRLTSLDDGAFKGLSNLKVLDLSNNLLTTLSPGAFSGLPSLRYLDLSGNRL 61
LRR COG4886
Leucine-rich repeat (LRR) protein [Transcription];
110-240 1.44e-14

Leucine-rich repeat (LRR) protein [Transcription];


Pssm-ID: 443914 [Multi-domain]  Cd Length: 414  Bit Score: 76.90  E-value: 1.44e-14
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1820048647 110 HLLLSGNLLSRLyPNEFVNYTGASILHLGSNVIQDIETgAFHGLRGLRRLHLNNNKLELLrDDTFLGLENLEYLQVDYNY 189
Cdd:COG4886   163 SLDLSNNQLTDL-PEELGNLTNLKELDLSNNQITDLPE-PLGNLTNLEELDLSGNQLTDL-PEPLANLTNLETLDLSNNQ 239

                          90       100       110       120       130
                  ....*....|....*....|....*....|....*....|....*....|.
gi 1820048647 190 ISVIEpnAFGKLHMLQVLILNDNLLSGLPNnLFRFVPLTHLDLRGNRLKLL 240
Cdd:COG4886   240 LTDLP--ELGNLTNLEELDLSNNQLTDLPP-LANLTNLKTLDLSNNQLTDL 287
LRR_8 pfam13855
Leucine rich repeat;
134-190 1.47e-12

Leucine rich repeat;


Pssm-ID: 404697 [Multi-domain]  Cd Length: 61  Bit Score: 63.31  E-value: 1.47e-12
                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|....*..
gi 1820048647 134 ILHLGSNVIQDIETGAFHGLRGLRRLHLNNNKLELLRDDTFLGLENLEYLQVDYNYI 190
Cdd:pfam13855   5 SLDLSNNRLTSLDDGAFKGLSNLKVLDLSNNLLTTLSPGAFSGLPSLRYLDLSGNRL 61
PPP1R42 cd21340
protein phosphatase 1 regulatory subunit 42; Protein phosphatase 1 regulatory subunit 42 ...
 416-588 9.68e-12

protein phosphatase 1 regulatory subunit 42; Protein phosphatase 1 regulatory subunit 42 (PPP1R42), also known as leucine-rich repeat-containing protein 67 (lrrc67) or testis leucine-rich repeat (TLRR) protein, plays a role in centrosome separation. PPP1R42 has been shown to interact with the well-conserved signaling protein phosphatase-1 (PP1) and thereby increasing PP1's activity, which counters centrosome separation. Inhibition of PPP1R42 expression increases the number of centrosomes per cell while its depletion reduces the activity of PP1 leading to activation of NEK2, the kinase responsible for phosphorylation of centrosomal linker proteins promoting centrosome separation.


Pssm-ID: 411060 [Multi-domain]  Cd Length: 220  Bit Score: 65.58  E-value: 9.68e-12
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1820048647 416 VNCQERKIESIAELQPKPyNPKKMYLTENYITVVRRTDFLeaTGLDLLHLGNNRISMIQDraFGDLGNLRRLYLNGNRIE 495
Cdd:cd21340     7 LYLNDKNITKIDNLSLCK-NLKVLYLYDNKITKIENLEFL--TNLTHLYLQNNQIEKIEN--LENLVNLKKLYLGGNRIS 81

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1820048647 496 RLspELFYGLQSLQYLFLQYNLIREIQAGTFDPvpnlqllflnnnqlqampsgvFSGLTLLR----LNLRGNSFTSLpvs 571
Cdd:cd21340    82 VV--EGLENLTNLEELHIENQRLPPGEKLTFDP---------------------RSLAALSNslrvLNISGNNIDSL--- 135

                         170
                  ....*....|....*..
gi 1820048647 572 GVLDQLTSLIQIDLHDN 588
Cdd:cd21340   136 EPLAPLRNLEQLDASNN 152
LRR_8 pfam13855
Leucine rich repeat;
179-237 1.35e-10

Leucine rich repeat;


Pssm-ID: 404697 [Multi-domain]  Cd Length: 61  Bit Score: 57.53  E-value: 1.35e-10
                          10        20        30        40        50        60
                  ....*....|....*....|....*....|....*....|....*....|....*....|
gi 1820048647 179 NLEYLQVDYNYISVIEPNAFGKLHMLQVLILNDNLLSGLPNNLFRFVP-LTHLDLRGNRL 237
Cdd:pfam13855   2 NLRSLDLSNNRLTSLDDGAFKGLSNLKVLDLSNNLLTTLSPGAFSGLPsLRYLDLSGNRL 61
LRR_8 pfam13855
Leucine rich repeat;
483-565 5.33e-10

Leucine rich repeat;


Pssm-ID: 404697 [Multi-domain]  Cd Length: 61  Bit Score: 55.99  E-value: 5.33e-10
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1820048647 483 NLRRLYLNGNRIERLSPELFYGLQSLQYLFLQYNLIREIqagtfdpvpnlqllflnnnqlqamPSGVFSGLTLLR-LNLR 561
Cdd:pfam13855   2 NLRSLDLSNNRLTSLDDGAFKGLSNLKVLDLSNNLLTTL------------------------SPGAFSGLPSLRyLDLS 57


                  ....
gi 1820048647 562 GNSF 565
Cdd:pfam13855  58 GNRL 61
LRR COG4886
Leucine-rich repeat (LRR) protein [Transcription];
452-588 9.43e-10

Leucine-rich repeat (LRR) protein [Transcription];


Pssm-ID: 443914 [Multi-domain]  Cd Length: 414  Bit Score: 61.87  E-value: 9.43e-10
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1820048647 452 TDFLEATGLDLLHLGNNRISMIqDRAFGDLGNLRRLYLNGNRIERLSPELFyGLQSLQYLFLQYNLIREIQAGtFDPVPN 531
Cdd:COG4886   107 EELSNLTNLESLDLSGNQLTDL-PEELANLTNLKELDLSNNQLTDLPEPLG-NLTNLKSLDLSNNQLTDLPEE-LGNLTN 183

                          90       100       110       120       130
                  ....*....|....*....|....*....|....*....|....*....|....*...
gi 1820048647 532 LQLLFLNNNQLQAMPSgVFSGLTLLR-LNLRGNSFTSLPVSgvLDQLTSLIQIDLHDN 588
Cdd:COG4886   184 LKELDLSNNQITDLPE-PLGNLTNLEeLDLSGNQLTDLPEP--LANLTNLETLDLSNN 238
LRR_8 pfam13855
Leucine rich repeat;
437-494 5.11e-09

Leucine rich repeat;


Pssm-ID: 404697 [Multi-domain]  Cd Length: 61  Bit Score: 53.30  E-value: 5.11e-09
                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|....*...
gi 1820048647 437 KKMYLTENYITVVRRTDFLEATGLDLLHLGNNRISMIQDRAFGDLGNLRRLYLNGNRI 494
Cdd:pfam13855   4 RSLDLSNNRLTSLDDGAFKGLSNLKVLDLSNNLLTTLSPGAFSGLPSLRYLDLSGNRL 61
PPP1R42 cd21340
protein phosphatase 1 regulatory subunit 42; Protein phosphatase 1 regulatory subunit 42 ...
 110-260 5.94e-08

protein phosphatase 1 regulatory subunit 42; Protein phosphatase 1 regulatory subunit 42 (PPP1R42), also known as leucine-rich repeat-containing protein 67 (lrrc67) or testis leucine-rich repeat (TLRR) protein, plays a role in centrosome separation. PPP1R42 has been shown to interact with the well-conserved signaling protein phosphatase-1 (PP1) and thereby increasing PP1's activity, which counters centrosome separation. Inhibition of PPP1R42 expression increases the number of centrosomes per cell while its depletion reduces the activity of PP1 leading to activation of NEK2, the kinase responsible for phosphorylation of centrosomal linker proteins promoting centrosome separation.


Pssm-ID: 411060 [Multi-domain]  Cd Length: 220  Bit Score: 54.41  E-value: 5.94e-08
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1820048647 110 HLLLSGNLLSRLypNEFVNYTGASILHLGSNVIQDIEtgAFHGLRGLRRLHLNNNKLELLRDdtFLGLENLEYLQVDYNY 189
Cdd:cd21340     6 HLYLNDKNITKI--DNLSLCKNLKVLYLYDNKITKIE--NLEFLTNLTHLYLQNNQIEKIEN--LENLVNLKKLYLGGNR 79

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1820048647 190 ISVIEpnAFGKLHMLQVL-ILNDNLLSGLPnnlFRFVP---------LTHLDLRGNRlklLPYVGLLQHMDKVVELQLEE 259
Cdd:cd21340    80 ISVVE--GLENLTNLEELhIENQRLPPGEK---LTFDPrslaalsnsLRVLNISGNN---IDSLEPLAPLRNLEQLDASN 151


                  .
gi 1820048647 260 N 260
Cdd:cd21340   152 N 152
LRR COG4886
Leucine-rich repeat (LRR) protein [Transcription];
91-522 8.06e-08

Leucine-rich repeat (LRR) protein [Transcription];


Pssm-ID: 443914 [Multi-domain]  Cd Length: 414  Bit Score: 55.71  E-value: 8.06e-08
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1820048647  91 ENRGIISLSEISPPRFPIYHLLLSGNLLSRLYPNEFVNYTGASILHLGSNVIQDI-ETGAFHGLRGLRRLHLNNNKLELL 169
Cdd:COG4886    49 LTLLLSLLLRDLLLSSLLLLLSLLLLLLLSLLLLSLLLLGLTDLGDLTNLTELDLsGNEELSNLTNLESLDLSGNQLTDL 128

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1820048647 170 rDDTFLGLENLEYLQVDYNYISVIePNAFGKLHMLQVLILNDNLLSGLPNNLFRFVPLTHLDLRGNRLKLLPYVglLQHM 249
Cdd:COG4886   129 -PEELANLTNLKELDLSNNQLTDL-PEPLGNLTNLKSLDLSNNQLTDLPEELGNLTNLKELDLSNNQITDLPEP--LGNL 204

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1820048647 250 DKVVELQLEENpwncscelislkdwldsisysalvgdvvcetpfrlhgrdldevskqelcprklisdyemrpqtplsttg 329
Cdd:COG4886   205 TNLEELDLSGN--------------------------------------------------------------------- 215

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1820048647 330 ylhttpasvnsvatsssavykpplkppkgtrqpnkprvrptsrqpskdlgysnygpsiayqtkspvplecptactcnlQI 409
Cdd:COG4886   216 ------------------------------------------------------------------------------QL 217

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1820048647 410 SDLGlnvncqerkiESIAELqpkpynpkkmyltenyitvvrrtdfleaTGLDLLHLGNNRISMIqdRAFGDLGNLRRLYL 489
Cdd:COG4886   218 TDLP----------EPLANL----------------------------TNLETLDLSNNQLTDL--PELGNLTNLEELDL 257

                         410       420       430
                  ....*....|....*....|....*....|...
gi 1820048647 490 NGNRIERLSPELfyGLQSLQYLFLQYNLIREIQ 522
Cdd:COG4886   258 SNNQLTDLPPLA--NLTNLKTLDLSNNQLTDLK 288
LRR COG4886
Leucine-rich repeat (LRR) protein [Transcription];
91-260 6.02e-07

Leucine-rich repeat (LRR) protein [Transcription];


Pssm-ID: 443914 [Multi-domain]  Cd Length: 414  Bit Score: 53.01  E-value: 6.02e-07
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1820048647  91 ENRGIISLSEISPPRFPIYHLLLSGNLLSRLYPNEFVNYTGAS-ILHLGSNVIQDIETGAFHGLRGLRRLHLNNNKLELL 169
Cdd:COG4886     8 LTLKLLLLLLLELLTTLILLLLLLLLLLALLLLSLLSLLLLLTlLLSLLLRDLLLSSLLLLLSLLLLLLLSLLLLSLLLL 87

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1820048647 170 RDDTFLGLENLEYLQVDYNyisviepNAFGKLHMLQVLILNDNLLSGLPNNLFRFVPLTHLDLRGNRLKLLPYVglLQHM 249
Cdd:COG4886    88 GLTDLGDLTNLTELDLSGN-------EELSNLTNLESLDLSGNQLTDLPEELANLTNLKELDLSNNQLTDLPEP--LGNL 158

                         170
                  ....*....|.
gi 1820048647 250 DKVVELQLEEN 260
Cdd:COG4886   159 TNLKSLDLSNN 169
PPP1R42 cd21340
protein phosphatase 1 regulatory subunit 42; Protein phosphatase 1 regulatory subunit 42 ...
 110-235 1.17e-06

protein phosphatase 1 regulatory subunit 42; Protein phosphatase 1 regulatory subunit 42 (PPP1R42), also known as leucine-rich repeat-containing protein 67 (lrrc67) or testis leucine-rich repeat (TLRR) protein, plays a role in centrosome separation. PPP1R42 has been shown to interact with the well-conserved signaling protein phosphatase-1 (PP1) and thereby increasing PP1's activity, which counters centrosome separation. Inhibition of PPP1R42 expression increases the number of centrosomes per cell while its depletion reduces the activity of PP1 leading to activation of NEK2, the kinase responsible for phosphorylation of centrosomal linker proteins promoting centrosome separation.


Pssm-ID: 411060 [Multi-domain]  Cd Length: 220  Bit Score: 50.55  E-value: 1.17e-06
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1820048647 110 HLLLSGNLLSRLypNEFVNYTGASILHLGSNVIQDIEtgAFHGLRGLRRLHLNNNKLE-----LLRDDTFLGL-ENLEYL 183
Cdd:cd21340    50 HLYLQNNQIEKI--ENLENLVNLKKLYLGGNRISVVE--GLENLTNLEELHIENQRLPpgeklTFDPRSLAALsNSLRVL 125

                          90       100       110       120       130
                  ....*....|....*....|....*....|....*....|....*....|....*.
gi 1820048647 184 QVDYNYISVIEPnaFGKLHMLQVLILNDNLLSGLpNNLFRFVP----LTHLDLRGN 235
Cdd:cd21340   126 NISGNNIDSLEP--LAPLRNLEQLDASNNQISDL-EELLDLLSswpsLRELDLTGN 178
LRRCT smart00082
Leucine rich repeat C-terminal domain;
260-298 1.21e-06

Leucine rich repeat C-terminal domain;


Pssm-ID: 214507 [Multi-domain]  Cd Length: 51  Bit Score: 46.27  E-value: 1.21e-06
                           10        20        30
                   ....*....|....*....|....*....|....*....
gi 1820048647  260 NPWNCSCELISLKDWLDSISYSALVGDVVCETPFRLHGR 298
Cdd:smart00082   1 NPFICDCELRWLLRWLQANEHLQDPVDLRCASPSSLRGP 39
PLN00113 PLN00113
leucine-rich repeat receptor-like protein kinase; Provisional
 111-237 1.86e-05

leucine-rich repeat receptor-like protein kinase; Provisional


Pssm-ID: 215061 [Multi-domain]  Cd Length: 968  Bit Score: 48.69  E-value: 1.86e-05
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1820048647 111 LLLSGNLLSRLYPNEFVNYTGASILHLGSNVIQDIETGAFHGLRGLRRLHLNNNKLELLRDDTFLGLENLEYLQVDYNYI 190
Cdd:PLN00113  169 LDLGGNVLVGKIPNSLTNLTSLEFLTLASNQLVGQIPRELGQMKSLKWIYLGYNNLSGEIPYEIGGLTSLNHLDLVYNNL 248

                          90       100       110       120
                  ....*....|....*....|....*....|....*....|....*...
gi 1820048647 191 SVIEPNAFGKLHMLQVLILNDNLLSG-LPNNLFRFVPLTHLDLRGNRL 237
Cdd:PLN00113  249 TGPIPSSLGNLKNLQYLFLYQNKLSGpIPPSIFSLQKLISLDLSDNSL 296
LRR COG4886
Leucine-rich repeat (LRR) protein [Transcription];
441-589 2.74e-05

Leucine-rich repeat (LRR) protein [Transcription];


Pssm-ID: 443914 [Multi-domain]  Cd Length: 414  Bit Score: 47.62  E-value: 2.74e-05
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1820048647 441 LTENYITVVRRTDFLEATGLDLLHLGNNRismiqdrAFGDLGNLRRLYLNGNRIERLsPELFYGLQSLQYLFlqynlire 520
Cdd:COG4886    79 LLLLSLLLLGLTDLGDLTNLTELDLSGNE-------ELSNLTNLESLDLSGNQLTDL-PEELANLTNLKELD-------- 142

                          90       100       110       120       130       140       150
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1820048647 521 iqagtfdpvpnlqllfLNNNQLQAMPSgVFSGLT-LLRLNLRGNSFTSLPVSgvLDQLTSLIQIDLHDNP 589
Cdd:COG4886   143 ----------------LSNNQLTDLPE-PLGNLTnLKSLDLSNNQLTDLPEE--LGNLTNLKELDLSNNQ 193
PLN00113 PLN00113
leucine-rich repeat receptor-like protein kinase; Provisional
 110-237 1.98e-04

leucine-rich repeat receptor-like protein kinase; Provisional


Pssm-ID: 215061 [Multi-domain]  Cd Length: 968  Bit Score: 45.61  E-value: 1.98e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1820048647 110 HLLLSGNLLSRLYPNEFVNYTGASILHLGSNVIQDIETGAFHGLRGLRRLHLNNNKLELLRDDTFLGLENLEYLQVDYNY 189
Cdd:PLN00113  240 HLDLVYNNLTGPIPSSLGNLKNLQYLFLYQNKLSGPIPPSIFSLQKLISLDLSDNSLSGEIPELVIQLQNLEILHLFSNN 319

                          90       100       110       120
                  ....*....|....*....|....*....|....*....|....*....
gi 1820048647 190 ISVIEPNAFGKLHMLQVLILNDNLLSG-LPNNLFRFVPLTHLDLRGNRL 237
Cdd:PLN00113  320 FTGKIPVALTSLPRLQVLQLWSNKFSGeIPKNLGKHNNLTVLDLSTNNL 368
PLN03150 PLN03150
hypothetical protein; Provisional
 153-216 3.56e-04

hypothetical protein; Provisional


Pssm-ID: 178695 [Multi-domain]  Cd Length: 623  Bit Score: 44.42  E-value: 3.56e-04
                          10        20        30        40        50        60
                  ....*....|....*....|....*....|....*....|....*....|....*....|....
gi 1820048647 153 LRGLRRLHLNNNKLELLRDDTFLGLENLEYLQVDYNYISVIEPNAFGKLHMLQVLILNDNLLSG 216
Cdd:PLN03150  441 LRHLQSINLSGNSIRGNIPPSLGSITSLEVLDLSYNSFNGSIPESLGQLTSLRILNLNGNSLSG 504
LRR_8 pfam13855
Leucine rich repeat;
204-261 4.04e-04

Leucine rich repeat;


Pssm-ID: 404697 [Multi-domain]  Cd Length: 61  Bit Score: 39.43  E-value: 4.04e-04
                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|....*....
gi 1820048647 204 LQVLILNDNLLSGLPNNLFRFVP-LTHLDLRGNRLKLLPYvGLLQHMDKVVELQLEENP 261
Cdd:pfam13855   3 LRSLDLSNNRLTSLDDGAFKGLSnLKVLDLSNNLLTTLSP-GAFSGLPSLRYLDLSGNR 60
RNA1 COG5238
Ran GTPase-activating protein (RanGAP) involved in mRNA processing and transport [Translation, ...
 406-520 1.14e-03

Ran GTPase-activating protein (RanGAP) involved in mRNA processing and transport [Translation, ribosomal structure and biogenesis];


Pssm-ID: 444072 [Multi-domain]  Cd Length: 434  Bit Score: 42.47  E-value: 1.14e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1820048647 406 NLQISDLGLNvNCQERKIESIAELQPKPYNPKKMYLTENYITVVRRTDFLEA----TGLDLLHLGNNRISmiqDRAFGDL 481
Cdd:COG5238   181 SVETVYLGCN-QIGDEGIEELAEALTQNTTVTTLWLKRNPIGDEGAEILAEAlkgnKSLTTLDLSNNQIG---DEGVIAL 256

                          90       100       110       120       130
                  ....*....|....*....|....*....|....*....|....*....|
gi 1820048647 482 G-------NLRRLYLNGNRIE----RLSPELFYGLQSLQYLFLQYNLIRE 520
Cdd:COG5238   257 AealknntTVETLYLSGNQIGaegaIALAKALQGNTTLTSLDLSVNRIGD 306
PLN00113 PLN00113
leucine-rich repeat receptor-like protein kinase; Provisional
 113-237 1.51e-03

leucine-rich repeat receptor-like protein kinase; Provisional


Pssm-ID: 215061 [Multi-domain]  Cd Length: 968  Bit Score: 42.53  E-value: 1.51e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1820048647 113 LSGNLLSRLYPNEFVNYTGASILHLGSNVIQ-DIETGAFHgLRGLRRLHLNNNKLELLRDDTFlGLENLEYLQVDYNYIS 191
Cdd:PLN00113  411 LQDNSFSGELPSEFTKLPLVYFLDISNNNLQgRINSRKWD-MPSLQMLSLARNKFFGGLPDSF-GSKRLENLDLSRNQFS 488

                          90       100       110       120
                  ....*....|....*....|....*....|....*....|....*..
gi 1820048647 192 VIEPNAFGKLHMLQVLILNDNLLSG-LPNNLFRFVPLTHLDLRGNRL 237
Cdd:PLN00113  489 GAVPRKLGSLSELMQLKLSENKLSGeIPDELSSCKKLVSLDLSHNQL 535
LRR_4 pfam12799
Leucine Rich repeats (2 copies); Leucine rich repeats are short sequence motifs present in a ...
 483-523 2.49e-03

Leucine Rich repeats (2 copies); Leucine rich repeats are short sequence motifs present in a number of proteins with diverse functions and cellular locations. These repeats are usually involved in protein-protein interactions. Each Leucine Rich Repeat is composed of a beta-alpha unit. These units form elongated non-globular structures. Leucine Rich Repeats are often flanked by cysteine rich domains.


Pssm-ID: 463713 [Multi-domain]  Cd Length: 44  Bit Score: 36.45  E-value: 2.49e-03
                          10        20        30        40
                  ....*....|....*....|....*....|....*....|..
gi 1820048647 483 NLRRLYLNGNRIERLSPelFYGLQSLQYLFLQYN-LIREIQA 523
Cdd:pfam12799   2 NLEVLDLSNNQITDIPP--LAKLPNLETLDLSGNnKITDLSD 41
LRRCT smart00082
Leucine rich repeat C-terminal domain;
588-624 2.98e-03

Leucine rich repeat C-terminal domain;


Pssm-ID: 214507 [Multi-domain]  Cd Length: 51  Bit Score: 36.64  E-value: 2.98e-03
                           10        20        30
                   ....*....|....*....|....*....|....*..
gi 1820048647  588 NPWDCTCDVVGMKLWIEQLKVGVLVDEVICKAPKKFA 624
Cdd:smart00082   1 NPFICDCELRWLLRWLQANEHLQDPVDLRCASPSSLR 37
LRR smart00370
Leucine-rich repeats, outliers;
481-504 4.33e-03

Leucine-rich repeats, outliers;


Pssm-ID: 197688 [Multi-domain]  Cd Length: 24  Bit Score: 35.41  E-value: 4.33e-03
                           10        20
                   ....*....|....*....|....
gi 1820048647  481 LGNLRRLYLNGNRIERLSPELFYG 504
Cdd:smart00370   1 LPNLRELDLSNNQLSSLPPGAFQG 24
LRR_TYP smart00369
Leucine-rich repeats, typical (most populated) subfamily;
481-504 4.33e-03

Leucine-rich repeats, typical (most populated) subfamily;


Pssm-ID: 197687 [Multi-domain]  Cd Length: 24  Bit Score: 35.41  E-value: 4.33e-03
                           10        20
                   ....*....|....*....|....
gi 1820048647  481 LGNLRRLYLNGNRIERLSPELFYG 504
Cdd:smart00369   1 LPNLRELDLSNNQLSSLPPGAFQG 24
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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