NCBI Home Page NCBI Site Search page NCBI Guide that lists and describes the NCBI resources
Conserved domains on  [gi|1913184352|ref|NP_001374315|]
View 

dnaJ homolog subfamily A member 4 isoform 5 [Homo sapiens]

Protein Classification

J domain-containing protein( domain architecture ID 1002416)

J domain-containing protein similar to the N-terminal conserved domain (called J domain) of DnaJ-like proteins, which is involved in regulating the ATPase activity of heat shock protein 70 (Hsp70) by ATP hydrolysis

CATH:  1.10.287.110
Gene Ontology:  GO:0006457
PubMed:  9585179|23894646|15170475
SCOP:  4000605

Graphical summary

 Zoom to residue level

show extra options »

Show site features     Horizontal zoom: ×

List of domain hits

 Name Accession Description Interval E-value
PTZ00037 super family cl36499
DnaJ_C chaperone protein; Provisional
 2-317 1.38e-90

DnaJ_C chaperone protein; Provisional


The actual alignment was detected with superfamily member PTZ00037:

Pssm-ID: 240236 [Multi-domain]  Cd Length: 421  Bit Score: 276.32  E-value: 1.38e-90
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1913184352   2 VKETQYYDILGVKPSASPEEIKKAYRKLALKYHPDKNPDEgEKFKLISQAYEVLSDPKKRDVYDQGGEQAIKeggsGSPS 81
Cdd:PTZ00037   25 VDNEKLYEVLNLSKDCTTSEIKKAYRKLAIKHHPDKGGDP-EKFKEISRAYEVLSDPEKRKIYDEYGEEGLE----GGEQ 99

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1913184352  82 FSSPMDIFDMFFGGGGRMARERRGKNVVHQLSVTLEDLYNGVTKKLALQKNVICEKCEGVGGKKGSVEKCPLCKGRGMQI 161
Cdd:PTZ00037  100 PADASDLFDLIFGGGRKPGGKKRGEDIVSHLKVTLEQIYNGAMRKLAINKDVICANCEGHGGPKDAFVDCKLCNGQGIRV 179

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1913184352 162 HIQQIGPgMVQQIQTVCIECKGQGERINPKDRCESCSGAKVIREKKIIEVHVEKG------------------------- 216
Cdd:PTZ00037  180 QIRQMGS-MIHQTQSTCNSCNGQGKIIPESKKCKNCSGKGVKKTRKILEVNIDKGvpnqhkitfhgeadekpneipgnvv 258

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1913184352 217 ----------------------------------------------------EVIKHGDLRCVRDEGMPIYKAPLEKGIL 244
Cdd:PTZ00037  259 filnekphdtfkreggdlfitkkislyealtgfvfyithldgrkllvntppgEVVKPGDIKVINNEGMPTYKSPFKKGNL 338

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1913184352 245 IIQFLVIFPEKHWLSLEKLPQLEALLPPRQKVRITDDMDQVEL---KEFCPNEQNWRQHREAYEEDEDGPQAG----VQC 317
Cdd:PTZ00037  339 YVTFEVIFPVDRKFTNEEKEILKSLFPQNPEEKKDLEDTEIEVvtaQNVDPEEVKDRDQKQQYQEDEDDEHHQegerVAC 418
 
Name Accession Description Interval E-value
PTZ00037 PTZ00037
DnaJ_C chaperone protein; Provisional
 2-317 1.38e-90

DnaJ_C chaperone protein; Provisional


Pssm-ID: 240236 [Multi-domain]  Cd Length: 421  Bit Score: 276.32  E-value: 1.38e-90
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1913184352   2 VKETQYYDILGVKPSASPEEIKKAYRKLALKYHPDKNPDEgEKFKLISQAYEVLSDPKKRDVYDQGGEQAIKeggsGSPS 81
Cdd:PTZ00037   25 VDNEKLYEVLNLSKDCTTSEIKKAYRKLAIKHHPDKGGDP-EKFKEISRAYEVLSDPEKRKIYDEYGEEGLE----GGEQ 99

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1913184352  82 FSSPMDIFDMFFGGGGRMARERRGKNVVHQLSVTLEDLYNGVTKKLALQKNVICEKCEGVGGKKGSVEKCPLCKGRGMQI 161
Cdd:PTZ00037  100 PADASDLFDLIFGGGRKPGGKKRGEDIVSHLKVTLEQIYNGAMRKLAINKDVICANCEGHGGPKDAFVDCKLCNGQGIRV 179

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1913184352 162 HIQQIGPgMVQQIQTVCIECKGQGERINPKDRCESCSGAKVIREKKIIEVHVEKG------------------------- 216
Cdd:PTZ00037  180 QIRQMGS-MIHQTQSTCNSCNGQGKIIPESKKCKNCSGKGVKKTRKILEVNIDKGvpnqhkitfhgeadekpneipgnvv 258

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1913184352 217 ----------------------------------------------------EVIKHGDLRCVRDEGMPIYKAPLEKGIL 244
Cdd:PTZ00037  259 filnekphdtfkreggdlfitkkislyealtgfvfyithldgrkllvntppgEVVKPGDIKVINNEGMPTYKSPFKKGNL 338

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1913184352 245 IIQFLVIFPEKHWLSLEKLPQLEALLPPRQKVRITDDMDQVEL---KEFCPNEQNWRQHREAYEEDEDGPQAG----VQC 317
Cdd:PTZ00037  339 YVTFEVIFPVDRKFTNEEKEILKSLFPQNPEEKKDLEDTEIEVvtaQNVDPEEVKDRDQKQQYQEDEDDEHHQegerVAC 418
DnaJ_bact TIGR02349
chaperone protein DnaJ; This model represents bacterial forms of DnaJ, part of the ...
 7-221 3.69e-69

chaperone protein DnaJ; This model represents bacterial forms of DnaJ, part of the DnaK-DnaJ-GrpE chaperone system. The three components typically are encoded by consecutive genes. DnaJ homologs occur in many genomes, typically not near DnaK and GrpE-like genes; most such genes are not included by this family. Eukaryotic (mitochondrial and chloroplast) forms are not included in the scope of this family.


Pssm-ID: 274090 [Multi-domain]  Cd Length: 354  Bit Score: 219.39  E-value: 3.69e-69
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1913184352   7 YYDILGVKPSASPEEIKKAYRKLALKYHPDKNPDEG--EKFKLISQAYEVLSDPKKRDVYDQGGEQAIKEGG-------- 76
Cdd:TIGR02349   2 YYEILGVSKDASEEEIKKAYRKLAKKYHPDRNKDKEaeEKFKEINEAYEVLSDPEKRAQYDQFGHAGFNGGGggggggfn 81

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1913184352  77 -SGSPSFSSPMDIFDMFFGGGGRMAR-----ERRGKNVVHQLSVTLEDLYNGVTKKLALQKNVICEKCEGVGGKKGS-VE 149
Cdd:TIGR02349  82 gFDIGFFGDFGDIFGDFFGGGGGSGRrrrsgPRRGEDLRYDLELTFEEAVFGVEKEIEIPRKESCETCHGTGAKPGTdPK 161

                         170       180       190       200       210       220       230
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 1913184352 150 KCPLCKGRGMQIHIQQIGPGMVQQIQTvCIECKGQGERInpKDRCESCSGAKVIREKKIIEVH----VEKGEVIKH 221
Cdd:TIGR02349 162 TCPTCGGTGQVRRQQGTPFGFFQQQQT-CPTCGGEGKII--KEPCSTCKGKGRVKERKTITVKipagVDTGQRLRV 234
DnaJ COG0484
DnaJ-class molecular chaperone with C-terminal Zn finger domain [Posttranslational ...
 7-74 1.88e-35

DnaJ-class molecular chaperone with C-terminal Zn finger domain [Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 440252 [Multi-domain]  Cd Length: 139  Bit Score: 125.20  E-value: 1.88e-35
                          10        20        30        40        50        60        70
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 1913184352   7 YYDILGVKPSASPEEIKKAYRKLALKYHPDKNPDEG---EKFKLISQAYEVLSDPKKRDVYDQGGEQAIKE 74
Cdd:COG0484     2 YYEILGVSRDASAEEIKKAYRKLAKKYHPDRNPGDPeaeEKFKEINEAYEVLSDPEKRAAYDRFGHAAELL 72
DnaJ pfam00226
DnaJ domain; DnaJ domains (J-domains) are associated with hsp70 heat-shock system and it is ...
 7-65 7.07e-34

DnaJ domain; DnaJ domains (J-domains) are associated with hsp70 heat-shock system and it is thought that this domain mediates the interaction. DnaJ-domain is therefore part of a chaperone (protein folding) system. The T-antigens, although not in Prosite are confirmed as DnaJ containing domains from literature.


Pssm-ID: 395170 [Multi-domain]  Cd Length: 63  Bit Score: 118.73  E-value: 7.07e-34
                          10        20        30        40        50        60
                  ....*....|....*....|....*....|....*....|....*....|....*....|..
gi 1913184352   7 YYDILGVKPSASPEEIKKAYRKLALKYHPDKNPDE---GEKFKLISQAYEVLSDPKKRDVYD 65
Cdd:pfam00226   2 YYEILGVSPDASDEEIKKAYRKLALKYHPDKNPGDpeaEEKFKEINEAYEVLSDPEKRAIYD 63
DnaJ smart00271
DnaJ molecular chaperone homology domain;
5-60 1.41e-26

DnaJ molecular chaperone homology domain;


Pssm-ID: 197617 [Multi-domain]  Cd Length: 60  Bit Score: 99.23  E-value: 1.41e-26
                           10        20        30        40        50        60
                   ....*....|....*....|....*....|....*....|....*....|....*....|
gi 1913184352    5 TQYYDILGVKPSASPEEIKKAYRKLALKYHPDKNPDE----GEKFKLISQAYEVLSDPKK 60
Cdd:smart00271   1 TDYYEILGVPRDASLDEIKKAYRKLALKYHPDKNPGDkeeaEEKFKEINEAYEVLSDPEK 60
DnaJ cd06257
DnaJ domain or J-domain. DnaJ/Hsp40 (heat shock protein 40) proteins are highly conserved and ...
 7-57 2.24e-26

DnaJ domain or J-domain. DnaJ/Hsp40 (heat shock protein 40) proteins are highly conserved and play crucial roles in protein translation, folding, unfolding, translocation, and degradation. They act primarily by stimulating the ATPase activity of Hsp70s, an important chaperonine family. Hsp40 proteins are characterized by the presence of a J domain, which mediates the interaction with Hsp70. They may contain other domains as well, and the architectures provide a means of classification.


Pssm-ID: 99751 [Multi-domain]  Cd Length: 55  Bit Score: 98.77  E-value: 2.24e-26
                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|....
gi 1913184352   7 YYDILGVKPSASPEEIKKAYRKLALKYHPDKNPDE---GEKFKLISQAYEVLSD 57
Cdd:cd06257     2 YYDILGVPPDASDEEIKKAYRKLALKYHPDKNPDDpeaEEKFKEINEAYEVLSD 55
 
Name Accession Description Interval E-value
PTZ00037 PTZ00037
DnaJ_C chaperone protein; Provisional
 2-317 1.38e-90

DnaJ_C chaperone protein; Provisional


Pssm-ID: 240236 [Multi-domain]  Cd Length: 421  Bit Score: 276.32  E-value: 1.38e-90
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1913184352   2 VKETQYYDILGVKPSASPEEIKKAYRKLALKYHPDKNPDEgEKFKLISQAYEVLSDPKKRDVYDQGGEQAIKeggsGSPS 81
Cdd:PTZ00037   25 VDNEKLYEVLNLSKDCTTSEIKKAYRKLAIKHHPDKGGDP-EKFKEISRAYEVLSDPEKRKIYDEYGEEGLE----GGEQ 99

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1913184352  82 FSSPMDIFDMFFGGGGRMARERRGKNVVHQLSVTLEDLYNGVTKKLALQKNVICEKCEGVGGKKGSVEKCPLCKGRGMQI 161
Cdd:PTZ00037  100 PADASDLFDLIFGGGRKPGGKKRGEDIVSHLKVTLEQIYNGAMRKLAINKDVICANCEGHGGPKDAFVDCKLCNGQGIRV 179

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1913184352 162 HIQQIGPgMVQQIQTVCIECKGQGERINPKDRCESCSGAKVIREKKIIEVHVEKG------------------------- 216
Cdd:PTZ00037  180 QIRQMGS-MIHQTQSTCNSCNGQGKIIPESKKCKNCSGKGVKKTRKILEVNIDKGvpnqhkitfhgeadekpneipgnvv 258

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1913184352 217 ----------------------------------------------------EVIKHGDLRCVRDEGMPIYKAPLEKGIL 244
Cdd:PTZ00037  259 filnekphdtfkreggdlfitkkislyealtgfvfyithldgrkllvntppgEVVKPGDIKVINNEGMPTYKSPFKKGNL 338

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1913184352 245 IIQFLVIFPEKHWLSLEKLPQLEALLPPRQKVRITDDMDQVEL---KEFCPNEQNWRQHREAYEEDEDGPQAG----VQC 317
Cdd:PTZ00037  339 YVTFEVIFPVDRKFTNEEKEILKSLFPQNPEEKKDLEDTEIEVvtaQNVDPEEVKDRDQKQQYQEDEDDEHHQegerVAC 418
DnaJ_bact TIGR02349
chaperone protein DnaJ; This model represents bacterial forms of DnaJ, part of the ...
 7-221 3.69e-69

chaperone protein DnaJ; This model represents bacterial forms of DnaJ, part of the DnaK-DnaJ-GrpE chaperone system. The three components typically are encoded by consecutive genes. DnaJ homologs occur in many genomes, typically not near DnaK and GrpE-like genes; most such genes are not included by this family. Eukaryotic (mitochondrial and chloroplast) forms are not included in the scope of this family.


Pssm-ID: 274090 [Multi-domain]  Cd Length: 354  Bit Score: 219.39  E-value: 3.69e-69
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1913184352   7 YYDILGVKPSASPEEIKKAYRKLALKYHPDKNPDEG--EKFKLISQAYEVLSDPKKRDVYDQGGEQAIKEGG-------- 76
Cdd:TIGR02349   2 YYEILGVSKDASEEEIKKAYRKLAKKYHPDRNKDKEaeEKFKEINEAYEVLSDPEKRAQYDQFGHAGFNGGGggggggfn 81

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1913184352  77 -SGSPSFSSPMDIFDMFFGGGGRMAR-----ERRGKNVVHQLSVTLEDLYNGVTKKLALQKNVICEKCEGVGGKKGS-VE 149
Cdd:TIGR02349  82 gFDIGFFGDFGDIFGDFFGGGGGSGRrrrsgPRRGEDLRYDLELTFEEAVFGVEKEIEIPRKESCETCHGTGAKPGTdPK 161

                         170       180       190       200       210       220       230
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 1913184352 150 KCPLCKGRGMQIHIQQIGPGMVQQIQTvCIECKGQGERInpKDRCESCSGAKVIREKKIIEVH----VEKGEVIKH 221
Cdd:TIGR02349 162 TCPTCGGTGQVRRQQGTPFGFFQQQQT-CPTCGGEGKII--KEPCSTCKGKGRVKERKTITVKipagVDTGQRLRV 234
PRK10767 PRK10767
chaperone protein DnaJ; Provisional
 7-216 4.91e-60

chaperone protein DnaJ; Provisional


Pssm-ID: 236757 [Multi-domain]  Cd Length: 371  Bit Score: 196.13  E-value: 4.91e-60
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1913184352   7 YYDILGVKPSASPEEIKKAYRKLALKYHPDKNPDEG---EKFKLISQAYEVLSDPKKRDVYDQGGEQAIKEGGSGSPSFS 83
Cdd:PRK10767    6 YYEVLGVSRNASEDEIKKAYRKLAMKYHPDRNPGDKeaeEKFKEIKEAYEVLSDPQKRAAYDQYGHAAFEQGGGGGGFGG 85

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1913184352  84 SPM------DIFDMFFGG--GGRMARERRGKNVVHQLSVTLEDLYNGVTKKLALQKNVICEKCEGVGGKKG-SVEKCPLC 154
Cdd:PRK10767   86 GGGfgdifgDIFGDIFGGgrGGGRQRARRGADLRYNMEITLEEAVRGVTKEIRIPTLVTCDTCHGSGAKPGtSPKTCPTC 165

                         170       180       190       200       210       220
                  ....*....|....*....|....*....|....*....|....*....|....*....|..
gi 1913184352 155 KGRGmQIHIQQiGPGMVQQiqtVCIECKGQGERInpKDRCESCSGAKVIREKKIIEVHVEKG 216
Cdd:PRK10767  166 HGAG-QVRMQQ-GFFTVQQ---TCPTCHGRGKII--KDPCKKCHGQGRVEKEKTLSVKIPAG 220
PRK14298 PRK14298
chaperone protein DnaJ; Provisional
 1-216 2.83e-59

chaperone protein DnaJ; Provisional


Pssm-ID: 184612 [Multi-domain]  Cd Length: 377  Bit Score: 194.30  E-value: 2.83e-59
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1913184352   1 MVKETQYYDILGVKPSASPEEIKKAYRKLALKYHPDKN--PDEGEKFKLISQAYEVLSDPKKRDVYDQGGEQAI-----K 73
Cdd:PRK14298    1 MATTRDYYEILGLSKDASVEDIKKAYRKLAMKYHPDKNkePDAEEKFKEISEAYAVLSDAEKRAQYDRFGHAGIdnqysA 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1913184352  74 EGGSGSPSFSSPMDIFDMFFGGGGRMARE--RRGKNVVHQLSVTLEDLYNGVTKKLALQKNVICEKCEGVGGKKGSVEK- 150
Cdd:PRK14298   81 EDIFRGADFGGFGDIFEMFFGGGGRRGRMgpRRGSDLRYDLYITLEEAAFGVRKDIDVPRAERCSTCSGTGAKPGTSPKr 160

                         170       180       190       200       210       220
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 1913184352 151 CPLCKGRGmQIHIQQIGPGMVQQIQTVCIECKGQGERInpKDRCESCSGAKVIREKKIIEVHVEKG 216
Cdd:PRK14298  161 CPTCGGTG-QVTTTRSTPLGQFVTTTTCSTCHGRGQVI--ESPCPVCSGTGKVRKTRKITVNVPAG 223
PRK14289 PRK14289
molecular chaperone DnaJ;
1-216 7.33e-57

molecular chaperone DnaJ;


Pssm-ID: 237660 [Multi-domain]  Cd Length: 386  Bit Score: 188.50  E-value: 7.33e-57
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1913184352   1 MVKETQYYDILGVKPSASPEEIKKAYRKLALKYHPDKNP---DEGEKFKLISQAYEVLSDPKKRDVYDQGGEQAIKEGGS 77
Cdd:PRK14289    1 MAEKRDYYEVLGVSKTATVDEIKKAYRKKAIQYHPDKNPgdkEAEEKFKEAAEAYDVLSDPDKRSRYDQFGHAGVGGAAG 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1913184352  78 GSPSFSSPM---DIFDMF----------------FGGGGRMARERRGKNVVHQLSVTLEDLYNGVTKKLALQKNVICEKC 138
Cdd:PRK14289   81 GGGFSGEGMsmeDIFSMFgdifgghgggfggfggFGGGGSQQRVFRGSDLRVKVKLNLKEISTGVEKKFKVKKYVPCSHC 160

                         170       180       190       200       210       220       230
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 1913184352 139 EGVGGK-KGSVEKCPLCKGRGMQIHIQQIGPGMVQQiQTVCIECKGQGERInpKDRCESCSGAKVIREKKIIEVHVEKG 216
Cdd:PRK14289  161 HGTGAEgNNGSETCPTCKGSGSVTRVQNTILGTMQT-QSTCPTCNGEGKII--KKKCKKCGGEGIVYGEEVITVKIPAG 236
PRK14278 PRK14278
chaperone protein DnaJ; Provisional
 5-216 6.30e-54

chaperone protein DnaJ; Provisional


Pssm-ID: 237654 [Multi-domain]  Cd Length: 378  Bit Score: 180.63  E-value: 6.30e-54
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1913184352   5 TQYYDILGVKPSASPEEIKKAYRKLALKYHPDKNPDEG--EKFKLISQAYEVLSDPKKRDVYDQGG---EQAIKEGGSGS 79
Cdd:PRK14278    3 RDYYGLLGVSRNASDAEIKRAYRKLARELHPDVNPDEEaqEKFKEISVAYEVLSDPEKRRIVDLGGdplESAGGGGGGFG 82

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1913184352  80 PSFSSPMDIFDMFFGGG----GRMARERRGKNVVHQLSVTLEDLYNGVTKKLALQKNVICEKCEGVGGKKGSVEK-CPLC 154
Cdd:PRK14278   83 GGFGGLGDVFEAFFGGGaasrGPRGRVRPGSDSLLRMRLDLEECATGVTKQVTVDTAVLCDRCHGKGTAGDSKPVtCDTC 162

                         170       180       190       200       210       220
                  ....*....|....*....|....*....|....*....|....*....|....*....|....
gi 1913184352 155 KGRGmqiHIQQIGPGMVQQIQTV--CIECKGQGERInpKDRCESCSGAKVIREKKIIEVHVEKG 216
Cdd:PRK14278  163 GGRG---EVQTVQRSFLGQVMTSrpCPTCRGVGEVI--PDPCHECAGDGRVRARREITVKIPAG 221
PRK14280 PRK14280
molecular chaperone DnaJ;
7-216 6.79e-51

molecular chaperone DnaJ;


Pssm-ID: 237656 [Multi-domain]  Cd Length: 376  Bit Score: 172.60  E-value: 6.79e-51
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1913184352   7 YYDILGVKPSASPEEIKKAYRKLALKYHPDKNPDEG--EKFKLISQAYEVLSDPKKRDVYDQGGEQAIKEGGSGSPSFSS 84
Cdd:PRK14280    6 YYEVLGVSKSASKDEIKKAYRKLSKKYHPDINKEEGadEKFKEISEAYEVLSDDQKRAQYDQFGHAGPNQGFGGGGFGGG 85

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1913184352  85 PM-------DIFDMFFGGGGRMARE---RRGKNVVHQLSVTLEDLYNGVTKKLALQKNVICEKCEGVGGKKG-SVEKCPL 153
Cdd:PRK14280   86 DFgggfgfeDIFSSFFGGGGRRRDPnapRQGADLQYTMTLTFEEAVFGKEKEIEIPKEETCDTCHGSGAKPGtSKETCSH 165

                         170       180       190       200       210       220
                  ....*....|....*....|....*....|....*....|....*....|....*....|....
gi 1913184352 154 CKGRGmQIHIQQIGP-GMVQQiQTVCIECKGQGERInpKDRCESCSGAKVIREKKIIEVHVEKG 216
Cdd:PRK14280  166 CGGSG-QVSVEQNTPfGRVVN-RQTCPHCNGTGQEI--KEKCPTCHGKGKVRKRKKINVKIPAG 225
PRK14276 PRK14276
chaperone protein DnaJ; Provisional
 4-216 1.08e-50

chaperone protein DnaJ; Provisional


Pssm-ID: 237653 [Multi-domain]  Cd Length: 380  Bit Score: 172.19  E-value: 1.08e-50
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1913184352   4 ETQYYDILGVKPSASPEEIKKAYRKLALKYHPDKNPDEG--EKFKLISQAYEVLSDPKKRDVYDQ----------GGEQA 71
Cdd:PRK14276    3 NTEYYDRLGVSKDASQDEIKKAYRKLSKKYHPDINKEPGaeEKYKEVQEAYETLSDPQKRAAYDQygaaganggfGGGAG 82

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1913184352  72 IKEGGSGSPSFSSPMDIFDMFFGGGGRMAR---ERRGKNVVHQLSVTLEDLYNGVTKKLALQKNVICEKCEGVGGKKG-S 147
Cdd:PRK14276   83 GFGGFDGSGGFGGFEDIFSSFFGGGGARRNpnaPRQGDDLQYRVNLDFEEAIFGKEKEVSYNREATCHTCNGSGAKPGtS 162

                         170       180       190       200       210       220       230
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1913184352 148 VEKCPLCKGRGMqIHIQQIGP-GMVQQiQTVCIECKGQGERInpKDRCESCSGAKVIREKKIIEVHVEKG 216
Cdd:PRK14276  163 PVTCGKCHGSGV-ITVDTQTPlGMMRR-QVTCDVCHGTGKEI--KEPCQTCHGTGHEKQAHTVSVKIPAG 228
PRK14283 PRK14283
chaperone protein DnaJ; Provisional
 1-231 1.20e-50

chaperone protein DnaJ; Provisional


Pssm-ID: 184604 [Multi-domain]  Cd Length: 378  Bit Score: 171.93  E-value: 1.20e-50
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1913184352   1 MVKETQYYDILGVKPSASPEEIKKAYRKLALKYHPDKNPDEG--EKFKLISQAYEVLSDPKKRDVYDQGGE--------- 69
Cdd:PRK14283    1 MAEKRDYYEVLGVDRNADKKEIKKAYRKLARKYHPDVSEEEGaeEKFKEISEAYAVLSDDEKRQRYDQFGHagmdgfsqe 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1913184352  70 ---QAIKEGGSGSPSFSSPMDIFDMFFGGGGRMARERRGKNVVHQLSVTLEDLYNGVTKKLALQKNVICEKCEGVGGKKG 146
Cdd:PRK14283   81 difNNINFEDIFQGFGFGIGNIFDMFGFGGGSRHGPQRGADIYTEVEITLEEAASGVEKDIKVRHTKKCPVCNGSRAEPG 160

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1913184352 147 S-VEKCPLCKGRGMQIHIQQIGPGMVQQIQTvCIECKGQGERInpKDRCESCSGAKVIREKKIIEVHVEKGevIKHGDLR 225
Cdd:PRK14283  161 SeVKTCPTCGGTGQVKQVRNTILGQMMNVTT-CPDCQGEGKIV--EKPCSNCHGKGVVRETKTISVKIPAG--VETGSRL 235


                  ....*.
gi 1913184352 226 CVRDEG 231
Cdd:PRK14283  236 RVSGEG 241
PRK14297 PRK14297
molecular chaperone DnaJ;
7-216 1.06e-49

molecular chaperone DnaJ;


Pssm-ID: 184611 [Multi-domain]  Cd Length: 380  Bit Score: 169.58  E-value: 1.06e-49
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1913184352   7 YYDILGVKPSASPEEIKKAYRKLALKYHPDKNPDEG---EKFKLISQAYEVLSDPKKRDVYDQ---------GGEQAIKE 74
Cdd:PRK14297    6 YYEVLGLEKGASDDEIKKAFRKLAIKYHPDKNKGNKeaeEKFKEINEAYQVLSDPQKKAQYDQfgtadfngaGGFGSGGF 85

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1913184352  75 GGSGSPSFSSPMDIFDMFFGGGGRMARERR-----GKNVVHQLSVTLEDLYNGVTKKLALQKNVICEKCEGVGGKKGSVE 149
Cdd:PRK14297   86 GGFDFSDMGGFGDIFDSFFGGGFGSSSRRRngpqrGADIEYTINLTFEEAVFGVEKEISVTRNENCETCNGTGAKPGTSP 165

                         170       180       190       200       210       220
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 1913184352 150 K-CPLCKGRGmQIHIQQIGPGMVQQIQTVCIECKGQGERInpKDRCESCSGAKVIREKKIIEVHVEKG 216
Cdd:PRK14297  166 KtCDKCGGTG-QIRVQRNTPLGSFVSTTTCDKCGGSGKVI--EDPCNKCHGKGKVRKNRKIKVNVPAG 230
PRK14294 PRK14294
chaperone protein DnaJ; Provisional
 7-216 1.65e-48

chaperone protein DnaJ; Provisional


Pssm-ID: 237664 [Multi-domain]  Cd Length: 366  Bit Score: 166.09  E-value: 1.65e-48
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1913184352   7 YYDILGVKPSASPEEIKKAYRKLALKYHPDKNP---DEGEKFKLISQAYEVLSDPKKRDVYDQGGEQAIKEGGSGSPSFS 83
Cdd:PRK14294    6 YYEILGVTRDASEEEIKKSYRKLAMKYHPDRNPgdkEAEELFKEAAEAYEVLSDPKKRGIYDQYGHEGLSGTGFSGFSGF 85

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1913184352  84 SPM-----DIFDMFFG-GGGRMARE----RRGKNVVHQLSVTLEDLYNGVTKKLALQKNVICEKCEGVGGKKGS-VEKCP 152
Cdd:PRK14294   86 DDIfssfgDIFEDFFGfGGGRRGRSrtavRAGADLRYDLTLPFLEAAFGTEKEIRIQKLETCEECHGSGCEPGTsPTTCP 165

                         170       180       190       200       210       220
                  ....*....|....*....|....*....|....*....|....*....|....*....|....
gi 1913184352 153 LCKGRGMQIHIQqigpGMVqQIQTVCIECKGQGERInpKDRCESCSGAKVIREKKIIEVHVEKG 216
Cdd:PRK14294  166 QCGGSGQVTQSQ----GFF-SIRTTCPRCRGMGKVI--VSPCKTCHGQGRVRVSKTVQVKIPAG 222
PRK14291 PRK14291
chaperone protein DnaJ; Provisional
 7-216 8.18e-47

chaperone protein DnaJ; Provisional


Pssm-ID: 237661 [Multi-domain]  Cd Length: 382  Bit Score: 162.25  E-value: 8.18e-47
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1913184352   7 YYDILGVKPSASPEEIKKAYRKLALKYHPDKNPDEG--EKFKLISQAYEVLSDPKKRDVYDQGGEQAIKEGGSGSPSFSS 84
Cdd:PRK14291    5 YYEILGVSRNATQEEIKKAYRRLARKYHPDFNKNPEaeEKFKEINEAYQVLSDPEKRKLYDQFGHAAFSGSGQQQQGQEG 84

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1913184352  85 PMDIFDM--------------FFGGGGRMA--RERR--------GKNVVHQLSVTLEDLYNGVTKKLALQKNVICEKCEG 140
Cdd:PRK14291   85 FSDFGGGniediledvfdifgFGDIFGRRRatRERRktyqrpvkGEDIYQTVEISLEEAYTGTTVSLEVPRYVPCEACGG 164

                         170       180       190       200       210       220       230
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 1913184352 141 VGGKKGSVEK-CPLCKGRGmqiHIQQigPGMVQQIQTVCIECKGQGERINPkdrCESCSGAKVIREKKIIEVHVEKG 216
Cdd:PRK14291  165 TGYDPGSGEKvCPTCGGSG---EIYQ--RGGFFRISQTCPTCGGEGVLREP---CSKCNGRGLVIKKETIKVRIPPG 233
PRK14281 PRK14281
chaperone protein DnaJ; Provisional
 7-231 8.76e-47

chaperone protein DnaJ; Provisional


Pssm-ID: 237657 [Multi-domain]  Cd Length: 397  Bit Score: 162.28  E-value: 8.76e-47
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1913184352   7 YYDILGVKPSASPEEIKKAYRKLALKYHPDKNPDEG---EKFKLISQAYEVLSDPKKRDVYDQ------GGEQAIKEGGS 77
Cdd:PRK14281    5 YYEVLGVSRSADKDEIKKAYRKLALKYHPDKNPDNKeaeEHFKEVNEAYEVLSNDDKRRRYDQfghagvGSSAASGGGPG 84

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1913184352  78 GSPSFSSPMDIF----DMF-----------------FGGGGRMARER---RGKNVVHQLSVTLEDLYNGVTKKLALQKNV 133
Cdd:PRK14281   85 YGGGGGDFNDIFsafnDMFgggarrgggspfgfedvFGGGGRRRRASagiPGTDLKIRLKLTLEEIAKGVEKTLKIKKQV 164

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1913184352 134 ICEKCEGVGGKKGSVEKCPLCKGRGmqiHIQQIGPGMVQQIQ--TVCIECKGQGERInpKDRCESCSGAKVIREKKIIEV 211
Cdd:PRK14281  165 PCKECNGTGSKTGATETCPTCHGSG---EVRQASKTMFGQFVniTACPTCGGEGRVV--KDRCPACYGEGIKQGEVTVKV 239

                         250       260
                  ....*....|....*....|
gi 1913184352 212 HVEKGevIKHGDLRCVRDEG 231
Cdd:PRK14281  240 TVPAG--VQDGNYLTLRGQG 257
PRK14277 PRK14277
chaperone protein DnaJ; Provisional
 1-233 2.31e-46

chaperone protein DnaJ; Provisional


Pssm-ID: 184599 [Multi-domain]  Cd Length: 386  Bit Score: 161.12  E-value: 2.31e-46
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1913184352   1 MVKETQYYDILGVKPSASPEEIKKAYRKLALKYHPDKNPDEGE---KFKLISQAYEVLSDPKKRDVYDQGGEQAIKEGGS 77
Cdd:PRK14277    1 MAAKKDYYEILGVDRNATEEEIKKAYRRLAKKYHPDLNPGDKEaeqKFKEINEAYEILSDPQKRAQYDQFGHAAFDPGGF 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1913184352  78 GSPSFSSP------------------MDIFDMFFGGGGRMARE--RRGKNVVHQLSVTLEDLYNGVTKKLALQKNVICEK 137
Cdd:PRK14277   81 GQGGFGQGgfggggfdfdfggfgdifEDIFGDFFGTGRRRAETgpQKGADIRYDLELTFEEAAFGTEKEIEVERFEKCDV 160

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1913184352 138 CEGVGGKKGS-VEKCPLCKGRGmQIHIQQIGP-GMVQQIQTvCIECKGQGERInpKDRCESCSGAKVIREKKIIEVHVEK 215
Cdd:PRK14277  161 CKGSGAKPGSkPVTCPVCHGTG-QVRTRQNTPfGRIVNIRT-CDRCHGEGKII--TDPCNKCGGTGRIRRRRKIKVNIPA 236

                         250
                  ....*....|....*...
gi 1913184352 216 GevIKHGDLRCVRDEGMP 233
Cdd:PRK14277  237 G--IDDGQMITLRGEGEP 252
PRK14290 PRK14290
chaperone protein DnaJ; Provisional
 1-216 6.53e-43

chaperone protein DnaJ; Provisional


Pssm-ID: 172778 [Multi-domain]  Cd Length: 365  Bit Score: 151.24  E-value: 6.53e-43
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1913184352   1 MVKEtqYYDILGVKPSASPEEIKKAYRKLALKYHPDKNPDEG----EKFKLISQAYEVLSDPKKRDVYDQGGEQAIKEGG 76
Cdd:PRK14290    1 MAKD--YYKILGVDRNASQEDIKKAFRELAKKWHPDLHPGNKaeaeEKFKEISEAYEVLSDPQKRRQYDQTGTVDFGAGG 78

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1913184352  77 SGS-----PSFSSPMDIFDMFFGG----------GGRMARERRGKNVVHQLSVTLEDLYNGVTKKLALQKNVICEKCEGV 141
Cdd:PRK14290   79 SNFnwdnfTHFSDINDIFNQIFGGnfgsdffsgfGNQQSTRNIDLDIYTNLDISLEDAYYGTEKRIKYRRNAMCPDCSGT 158

                         170       180       190       200       210       220       230
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 1913184352 142 GGKKGSVEKCPLCKGRGMQIHIQqiGPGMVQQIQ-TVCIECKGQGeRInPKDRCESCSGAKVIREKKIIEVHVEKG 216
Cdd:PRK14290  159 GAKNGKLITCPTCHGTGQQRIVR--GQGFFRMVTvTTCRTCGGRG-RI-PEEKCPRCNGTGTVVVNEDISVKIPKG 230
PRK14286 PRK14286
chaperone protein DnaJ; Provisional
 2-231 2.63e-42

chaperone protein DnaJ; Provisional


Pssm-ID: 172774 [Multi-domain]  Cd Length: 372  Bit Score: 150.14  E-value: 2.63e-42
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1913184352   2 VKETQYYDILGVKPSASPEEIKKAYRKLALKYHPDKN---PDEGEKFKLISQAYEVLSDPKKRDVYDQGGEQAIKEGGSG 78
Cdd:PRK14286    1 MSERSYYDILGVSKSANDEEIKSAYRKLAIKYHPDKNkgnKESEEKFKEATEAYEILRDPKKRQAYDQFGKAGVNAGAGG 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1913184352  79 SPSFSSP---------MDIFDMFFG-------GGGRMARERRGKNVVHQLSVTLEDLYNGVTKKLALQKNVICEKCEGVG 142
Cdd:PRK14286   81 FGQGAYTdfsdifgdfGDIFGDFFGggrgggsGGGRRSGPQRGSDLRYNLEVSLEDAALGREYKIEIPRLESCVDCNGSG 160

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1913184352 143 GKKGSVEK-CPLCKGRGmQIHIQQigpGMVqQIQTVCIECKGQGERI-NPkdrCESCSGAKVIREKKIIEVHVEKGevIK 220
Cdd:PRK14286  161 ASKGSSPTtCPDCGGSG-QIRRTQ---GFF-SVATTCPTCRGKGTVIsNP---CKTCGGQGLQEKRRTINIKIPPG--VE 230

                         250
                  ....*....|.
gi 1913184352 221 HGDLRCVRDEG 231
Cdd:PRK14286  231 TGSRLKVSGEG 241
PRK14301 PRK14301
chaperone protein DnaJ; Provisional
 7-233 4.27e-42

chaperone protein DnaJ; Provisional


Pssm-ID: 237668 [Multi-domain]  Cd Length: 373  Bit Score: 149.51  E-value: 4.27e-42
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1913184352   7 YYDILGVKPSASPEEIKKAYRKLALKYHPDKNPDEGE---KFKLISQAYEVLSDPKKRDVYDQGGEQAIKEGGSGSPSFS 83
Cdd:PRK14301    6 YYEVLGVSRDASEDEIKKAYRKLALQYHPDRNPDNPEaeqKFKEAAEAYEVLRDAEKRARYDRFGHAGVNGNGGFGGFSS 85

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1913184352  84 SP------MDIFDMFFG----GGGRMARERRGKNVVHQLSVTLEDLYNGVTKKLALQKNVICEKCEGVGGKKG-SVEKCP 152
Cdd:PRK14301   86 AEdifshfSDIFGDLFGfsggGSRRGPRPQAGSDLRYNLTVSFRQAAKGDEVTLRIPKNVTCDDCGGSGAAPGtSPETCR 165

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1913184352 153 LCKGRGmQIHIQQigpGMVqQIQTVCIECKGQGERInpKDRCESCSGAKVIREKKIIEVHVEKGevIKHGDLRCVRDEGM 232
Cdd:PRK14301  166 HCGGSG-QVRQSQ---GFF-QIAVPCPVCRGEGRVI--THPCPKCKGSGIVQQTRELKVRIPAG--VDTGSRLRLRGEGE 236


                  .
gi 1913184352 233 P 233
Cdd:PRK14301  237 P 237
PRK14284 PRK14284
chaperone protein DnaJ; Provisional
 5-216 3.59e-41

chaperone protein DnaJ; Provisional


Pssm-ID: 237658 [Multi-domain]  Cd Length: 391  Bit Score: 147.30  E-value: 3.59e-41
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1913184352   5 TQYYDILGVKPSASPEEIKKAYRKLALKYHPDKNPDEGE---KFKLISQAYEVLSDPKKRDVYDQGGEQA-IKEGGSGSP 80
Cdd:PRK14284    1 MDYYTILGVSKTASPEEIKKAYRKLAVKYHPDKNPGDAEaekRFKEVSEAYEVLSDAQKRESYDRYGKDGpFAGAGGFGG 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1913184352  81 SFSSPMD-------------------IFDMFFGG---------GGRMARERRGKNVvhQLSVTLEDLYNGVTKKLALQKN 132
Cdd:PRK14284   81 AGMGNMEdalrtfmgafggefggggsFFEGLFGGlgeafgmrgGPAGARQGASKKV--HITLSFEEAAKGVEKELLVSGY 158

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1913184352 133 VICEKCEGVGG-KKGSVEKCPLCKGRGmQIhIQQIGpgmVQQIQTVCIECKGQGERINpkDRCESCSGAKVIREKKIIEV 211
Cdd:PRK14284  159 KSCDACSGSGAnSSQGIKVCDRCKGSG-QV-VQSRG---FFSMASTCPECGGEGRVIT--DPCSVCRGQGRIKDKRSVHV 231


                  ....*
gi 1913184352 212 HVEKG 216
Cdd:PRK14284  232 HIPAG 236
PRK14295 PRK14295
molecular chaperone DnaJ;
4-216 1.20e-40

molecular chaperone DnaJ;


Pssm-ID: 237665 [Multi-domain]  Cd Length: 389  Bit Score: 146.15  E-value: 1.20e-40
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1913184352   4 ETQYYDILGVKPSASPEEIKKAYRKLALKYHPDKN---PDEGEKFKLISQAYEVLSDPKKRDVYD--------------- 65
Cdd:PRK14295    8 EKDYYKVLGVPKDATEAEIKKAYRKLAREYHPDANkgdAKAEERFKEISEAYDVLSDEKKRKEYDearslfgnggfrpgp 87

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1913184352  66 --------------------QGGEQAikeggsgsPSFSSPMDIFDMFFGGGGRMARERRGKNVVHQLSVTLEDLYNGVTK 125
Cdd:PRK14295   88 gggggggfnfdlgdlfgggaQGGGGA--------GGGGGLGDVFGGLFNRGGRRTQPRRGADVESEVTLSFTEAIDGATV 159

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1913184352 126 KLALQKNVICEKCEGVGGKKGSVEK-CPLCKGRGmqiHIQQIGPGMvqQIQTVCIECKGQGerINPKDRCESCSGAKVIR 204
Cdd:PRK14295  160 PLRLTSQAPCPACSGTGAKNGTTPRvCPTCSGTG---QVSRNSGGF--SLSEPCPDCKGRG--LIADDPCLVCKGSGRAK 232

                         250
                  ....*....|..
gi 1913184352 205 EKKIIEVHVEKG 216
Cdd:PRK14295  233 SSRTMQVRIPAG 244
PRK14293 PRK14293
molecular chaperone DnaJ;
7-216 1.25e-40

molecular chaperone DnaJ;


Pssm-ID: 237663 [Multi-domain]  Cd Length: 374  Bit Score: 145.52  E-value: 1.25e-40
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1913184352   7 YYDILGVKPSASPEEIKKAYRKLALKYHPDKNPDEG--EKFKLISQAYEVLSDPKKRDVYDQGGEQAIkeGGSGSPSFSS 84
Cdd:PRK14293    5 YYEILGVSRDADKDELKRAYRRLARKYHPDVNKEPGaeDRFKEINRAYEVLSDPETRARYDQFGEAGV--SGAAGFPDMG 82

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1913184352  85 PM----DIFDMFF------GGGGRMARER---RGKNVVHQLSVTLEDLYNGVTKKLALQKNVICEKCEGVGGKKGS-VEK 150
Cdd:PRK14293   83 DMggfaDIFETFFsgfggaGGQGGRRRRRgpqRGDDLRYDLKLDFREAIFGGEKEIRIPHLETCETCRGSGAKPGTgPTT 162

                         170       180       190       200       210       220
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 1913184352 151 CPLCKGRGmQIHIQQIGP-GMVQQIqTVCIECKGQGERInpKDRCESCSGAKVIREKKIIEVHVEKG 216
Cdd:PRK14293  163 CSTCGGAG-QVRRATRTPfGSFTQV-SECPTCNGTGQVI--EDPCDACGGQGVKQVTKKLKINIPAG 225
PRK14287 PRK14287
chaperone protein DnaJ; Provisional
 7-222 5.80e-39

chaperone protein DnaJ; Provisional


Pssm-ID: 237659 [Multi-domain]  Cd Length: 371  Bit Score: 141.30  E-value: 5.80e-39
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1913184352   7 YYDILGVKPSASPEEIKKAYRKLALKYHPD--KNPDEGEKFKLISQAYEVLSDPKKRDVYDQGGEQAIKE--GGSGSPSF 82
Cdd:PRK14287    6 YYEVLGVDRNASVDEVKKAYRKLARKYHPDvnKAPDAEDKFKEVKEAYDTLSDPQKKAHYDQFGHTDPNQgfGGGGAGDF 85

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1913184352  83 SSPMDIFDMFFGGGGRMAR---ERRGKNVVHQLSVTLEDLYNGVTKKLALQKNVICEKCEGVGGKKGSV-EKCPLCKGRG 158
Cdd:PRK14287   86 GGFSDIFDMFFGGGGGRRNpnaPRQGADLQYTMTLEFKEAVFGKETEIEIPREETCGTCHGSGAKPGTKpETCSHCGGSG 165

                         170       180       190       200       210       220
                  ....*....|....*....|....*....|....*....|....*....|....*....|....
gi 1913184352 159 mQIHIQQIGPGMVQQIQTVCIECKGQGERInpKDRCESCSGAKVIREKKIIEVHVEKGevIKHG 222
Cdd:PRK14287  166 -QLNVEQNTPFGRVVNRRVCHHCEGTGKII--KQKCATCGGKGKVRKRKKINVKVPAG--IDHG 224
PRK14285 PRK14285
chaperone protein DnaJ; Provisional
 7-216 1.05e-37

chaperone protein DnaJ; Provisional


Pssm-ID: 172773 [Multi-domain]  Cd Length: 365  Bit Score: 137.82  E-value: 1.05e-37
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1913184352   7 YYDILGVKPSASPEEIKKAYRKLALKYHPDKNPDEGEK---FKLISQAYEVLSDPKKRDVYDQGGEQAIKEGGSGSPSFS 83
Cdd:PRK14285    5 YYEILGLSKGASKDEIKKAYRKIAIKYHPDKNKGNKEAesiFKEATEAYEVLIDDNKRAQYDRFGHTAFEGGGGFEGFSG 84

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1913184352  84 SPM----------DIFDMFFGGGGRMARER---RGKNVVHQLSVTLEDLYNGVTKKLALQKNVICEKCEGVGGKKG-SVE 149
Cdd:PRK14285   85 GFSgfsdifedfgDIFDSFFTGNRGQDKNRkheKGQDLTYQIEISLEDAYLGYKNNINITRNMLCESCLGKKSEKGtSPS 164

                         170       180       190       200       210       220
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 1913184352 150 KCPLCKGRGMQIHiqqiGPGMVqQIQTVCIECKGQGERI-NPkdrCESCSGAKVIREKKIIEVHVEKG 216
Cdd:PRK14285  165 ICNMCNGSGRVMQ----GGGFF-RVTTTCPKCYGNGKIIsNP---CKSCKGKGSLKKKETIELKIPAG 224
PRK14292 PRK14292
chaperone protein DnaJ; Provisional
 7-216 1.82e-37

chaperone protein DnaJ; Provisional


Pssm-ID: 237662 [Multi-domain]  Cd Length: 371  Bit Score: 136.94  E-value: 1.82e-37
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1913184352   7 YYDILGVKPSASPEEIKKAYRKLALKYHPDKNPDEG--EKFKLISQAYEVLSDPKKRDVYDQGGEQ---AIKEGGSGSPS 81
Cdd:PRK14292    4 YYELLGVSRTASADEIKSAYRKLALKYHPDRNKEKGaaEKFAQINEAYAVLSDAEKRAHYDRFGTApgaGMPGGDPFGGM 83

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1913184352  82 FSSPMDIFDMFFGGGGRMA-----RERRGKNVVHQLSVTLEDLYNGVTKKLALQKNVICEKCEGVGGKKGS--VEKCPLC 154
Cdd:PRK14292   84 GFDPMDIFEQLFGGAGFGGgrgrrGPARGDDLETEARITLEQARAGEEVEVEVDRLTECEHCHGSRTEPGGkpPKTCPTC 163

                         170       180       190       200       210       220
                  ....*....|....*....|....*....|....*....|....*....|....*....|..
gi 1913184352 155 KGRGmQIHIQQIGPGMVQQIQTVCIECKGQGERInpKDRCESCSGAKVIREKKIIEVHVEKG 216
Cdd:PRK14292  164 RGAG-AVRAQARTIFGVVETQQPCPTCRGEGQII--TDPCTVCRGRGRTLKAETVKVKLPRG 222
PRK14279 PRK14279
molecular chaperone DnaJ;
4-216 3.37e-37

molecular chaperone DnaJ;


Pssm-ID: 237655 [Multi-domain]  Cd Length: 392  Bit Score: 136.79  E-value: 3.37e-37
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1913184352   4 ETQYYDILGVKPSASPEEIKKAYRKLALKYHPDKNPDE---GEKFKLISQAYEVLSDPKKRDVYDQ-------GGEQAIK 73
Cdd:PRK14279    8 EKDFYKELGVSSDASAEEIKKAYRKLARELHPDANPGDpaaEERFKAVSEAHDVLSDPAKRKEYDEtrrlfagGGFGGRR 87

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1913184352  74 EGGSG------SPSFSSPMDIFDMFFGGGG---------------------RMARERRGKNVVHQLSVTLEDLYNGVTKK 126
Cdd:PRK14279   88 FDGGGgfggfgTGGDGAEFNLNDLFDAAGRgggggigdlfgglfnrgggsaRPSRPRRGNDLETETTLDFVEAAKGVTMP 167

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1913184352 127 LALQKNVICEKCEGVGGKKG-SVEKCPLCKGRGMqIHIQQIGPGMVQQiqtvCIECKGQGERINpkDRCESCSGAKVIRE 205
Cdd:PRK14279  168 LRLTSPAPCTTCHGSGARPGtSPKVCPTCNGSGV-ISRNQGAFGFSEP----CTDCRGTGSIIE--DPCEECKGTGVTTR 240

                         250
                  ....*....|.
gi 1913184352 206 KKIIEVHVEKG 216
Cdd:PRK14279  241 TRTINVRIPPG 251
PRK14296 PRK14296
chaperone protein DnaJ; Provisional
 2-216 4.11e-36

chaperone protein DnaJ; Provisional


Pssm-ID: 237666 [Multi-domain]  Cd Length: 372  Bit Score: 133.53  E-value: 4.11e-36
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1913184352   2 VKETQYYDILGVKPSASPEEIKKAYRKLALKYHPD--KNPDEGEKFKLISQAYEVLSDPKKRDVYDQGGEQAIK------ 73
Cdd:PRK14296    1 MKKKDYYEVLGVSKTASEQEIRQAYRKLAKQYHPDlnKSPDAHDKMVEINEAADVLLDKDKRKQYDQFGHAAFDgssgfs 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1913184352  74 ------EGGSGSPSFSSPMDIFDMF--FGGGGRMARER--RGKNVVHQLSVTLEDLYNGVTKKLALQKNVICEKCEGVGG 143
Cdd:PRK14296   81 snfgdfEDLFSNMGSSGFSSFTNIFsdFFGSNKSDYQRstKGQSVSLDIYLTFKELLFGVDKIIELDLLTNCSKCFGSGA 160

                         170       180       190       200       210       220       230
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 1913184352 144 KKGS-VEKCPLCKGRGMQIHIQQIGPGMVQQiQTVCIECKGQGERInpKDRCESCSGAKVIREKKIIEVHVEKG 216
Cdd:PRK14296  161 ESNSdIHICNNCHGTGEVLVQKNMGFFQFQQ-SAKCNVCNGAGKII--KNKCKNCKGKGKYLERKKIEVNIPKG 231
DnaJ COG0484
DnaJ-class molecular chaperone with C-terminal Zn finger domain [Posttranslational ...
 7-74 1.88e-35

DnaJ-class molecular chaperone with C-terminal Zn finger domain [Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 440252 [Multi-domain]  Cd Length: 139  Bit Score: 125.20  E-value: 1.88e-35
                          10        20        30        40        50        60        70
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 1913184352   7 YYDILGVKPSASPEEIKKAYRKLALKYHPDKNPDEG---EKFKLISQAYEVLSDPKKRDVYDQGGEQAIKE 74
Cdd:COG0484     2 YYEILGVSRDASAEEIKKAYRKLAKKYHPDRNPGDPeaeEKFKEINEAYEVLSDPEKRAAYDRFGHAAELL 72
PRK14282 PRK14282
chaperone protein DnaJ; Provisional
 7-220 3.69e-35

chaperone protein DnaJ; Provisional


Pssm-ID: 184603 [Multi-domain]  Cd Length: 369  Bit Score: 131.07  E-value: 3.69e-35
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1913184352   7 YYDILGVKPSASPEEIKKAYRKLALKYHPDKNPDEG----EKFKLISQAYEVLSDPKKRDVYDQG---GEQAIKEGGSGS 79
Cdd:PRK14282    6 YYEILGVSRNATQEEIKRAYKRLVKEWHPDRHPENRkeaeQKFKEIQEAYEVLSDPQKRAMYDRFgyvGEQPPYQETESG 85

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1913184352  80 PSFSSPM----------DIFDMFFGGGG----RMARERRGKNVVHQLSVTLEDLYNGVTKKLALQKNVICEKCEGVGGKK 145
Cdd:PRK14282   86 GGFFEDIfkdfenifnrDIFDIFFGERRtqeeQREYARRGEDIRYEIEVTLSDLINGAEIPVEYDRYETCPHCGGTGVEP 165

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1913184352 146 GS-VEKCPLCKGRGMqIHIQQIGPGMVQQIQTVCIECKGQGeRInPKDRCESCSGAKVIREKKIIEVH----VEKGEVIK 220
Cdd:PRK14282  166 GSgYVTCPKCHGTGR-IREERRSFFGVFVSERTCERCGGTG-KI-PGEYCHECGGSGRIRRRVRTTVKipagVEDGTVLR 242
PRK14300 PRK14300
chaperone protein DnaJ; Provisional
 7-221 3.64e-34

chaperone protein DnaJ; Provisional


Pssm-ID: 172788 [Multi-domain]  Cd Length: 372  Bit Score: 128.21  E-value: 3.64e-34
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1913184352   7 YYDILGVKPSASPEEIKKAYRKLALKYHPDKNP--DEGEKFKLISQAYEVLSDPKKRDVYDQGGEQAIKEGGSGSPSFSS 84
Cdd:PRK14300    5 YYQILGVSKTASQADLKKAYLKLAKQYHPDTTDakDAEKKFKEINAAYDVLKDEQKRAAYDRFGHDAFQNQQSRGGGGNH 84

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1913184352  85 P------MDIFDMFFG---GGGRMARER----RGKNVVHQLSVTLEDLYNGVTKKLALQKNVICEKCEGVGGKKG-SVEK 150
Cdd:PRK14300   85 GgfhpdiNDIFGDFFSdfmGGSRRSRPTsskvRGSDLKYNLTINLEEAFHGIEKNISFSSEVKCDTCHGSGSEKGeTVTT 164

                         170       180       190       200       210       220       230
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 1913184352 151 CPLCKGRGMQiHIQQiGPGMVQQiqtVCIECKGQGERInpKDRCESCSGAKVIREKKIIEVH----VEKGEVIKH 221
Cdd:PRK14300  165 CDACSGVGAT-RMQQ-GFFTIEQ---ACHKCQGNGQII--KNPCKKCHGMGRYHKQRNLSVNipagVENGTRIRH 232
DnaJ pfam00226
DnaJ domain; DnaJ domains (J-domains) are associated with hsp70 heat-shock system and it is ...
 7-65 7.07e-34

DnaJ domain; DnaJ domains (J-domains) are associated with hsp70 heat-shock system and it is thought that this domain mediates the interaction. DnaJ-domain is therefore part of a chaperone (protein folding) system. The T-antigens, although not in Prosite are confirmed as DnaJ containing domains from literature.


Pssm-ID: 395170 [Multi-domain]  Cd Length: 63  Bit Score: 118.73  E-value: 7.07e-34
                          10        20        30        40        50        60
                  ....*....|....*....|....*....|....*....|....*....|....*....|..
gi 1913184352   7 YYDILGVKPSASPEEIKKAYRKLALKYHPDKNPDE---GEKFKLISQAYEVLSDPKKRDVYD 65
Cdd:pfam00226   2 YYEILGVSPDASDEEIKKAYRKLALKYHPDKNPGDpeaEEKFKEINEAYEVLSDPEKRAIYD 63
DnaJ_C pfam01556
DnaJ C terminal domain; This family consists of the C terminal region of the DnaJ protein. It ...
 108-250 2.82e-29

DnaJ C terminal domain; This family consists of the C terminal region of the DnaJ protein. It is always found associated with pfam00226 and pfam00684. DnaJ is a chaperone associated with the Hsp70 heat-shock system involved in protein folding and renaturation after stress. The two C-terminal domains CTDI and CTDII, both incorporated in this family are necessary for maintaining the J-domains in their specific relative positions. Structural analysis of PDB:1nlt shows that PF00684 is nested within this DnaJ C-terminal region.


Pssm-ID: 460251 [Multi-domain]  Cd Length: 213  Bit Score: 111.19  E-value: 2.82e-29
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1913184352 108 VVHQLSVTLEDLYNGVTKKLALQKNVICEKCEGVGGKKGSVEKCPLCKGRGMQIHIQqigpgmvQQIQTVCIECKGQGER 187
Cdd:pfam01556   1 LEYELELTLEEAYFGCTKKIKITRNVICDTCGGSGAKPGTSPKTCPCCGGGGQVRRQ-------FGFFSTCTCCPCCGGG 73

                          90       100       110       120       130       140
                  ....*....|....*....|....*....|....*....|....*....|....*....|....
gi 1913184352 188 INPKDRCESCSGAKVIREKKIIEVHVEKGevIKHGD-LRcVRDEGMPIYKaPLEKGILIIQFLV 250
Cdd:pfam01556  74 GKIIDKCCKCCGGGGVVEKKTLEVKIPAG--VDDGQrIR-LRGEGDAGEN-GGPPGDLYVVIRV 133
PRK14288 PRK14288
molecular chaperone DnaJ;
4-216 1.01e-28

molecular chaperone DnaJ;


Pssm-ID: 172776 [Multi-domain]  Cd Length: 369  Bit Score: 113.63  E-value: 1.01e-28
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1913184352   4 ETQYYDILGVKPSASPEEIKKAYRKLALKYHPDKNPDEG---EKFKLISQAYEVLSDPKKRDVYDQGGEQAIKEGGSGSP 80
Cdd:PRK14288    2 ELSYYEILEVEKHSNQETIKKSYRKLALKYHPDRNAGDKeaeEKFKLINEAYGVLSDEKKRALYDRYGKKGLNQAGASQS 81

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1913184352  81 SFSSPMD----IFDMFFGGGGRMARERRGK---NVVHQLSVTLEDLYNGVTKKLALQKNVICEKCEGVGGKKGSVEKCPL 153
Cdd:PRK14288   82 DFSDFFEdlgsFFEDAFGFGARGSKRQKSSiapDYLQTIELSFKEAVFGCKKTIKVQYQSVCESCDGTGAKDKALETCKQ 161

                         170       180       190       200       210       220
                  ....*....|....*....|....*....|....*....|....*....|....*....|...
gi 1913184352 154 CKGRGmQIHIQQigpGMVQQIQTvCIECKGQGERInpKDRCESCSGAKVIREKKIIEVHVEKG 216
Cdd:PRK14288  162 CNGQG-QVFMRQ---GFMSFAQT-CGACQGKGKII--KTPCQACKGKTYILKDEEIDAIIPEG 217
DnaJ smart00271
DnaJ molecular chaperone homology domain;
5-60 1.41e-26

DnaJ molecular chaperone homology domain;


Pssm-ID: 197617 [Multi-domain]  Cd Length: 60  Bit Score: 99.23  E-value: 1.41e-26
                           10        20        30        40        50        60
                   ....*....|....*....|....*....|....*....|....*....|....*....|
gi 1913184352    5 TQYYDILGVKPSASPEEIKKAYRKLALKYHPDKNPDE----GEKFKLISQAYEVLSDPKK 60
Cdd:smart00271   1 TDYYEILGVPRDASLDEIKKAYRKLALKYHPDKNPGDkeeaEEKFKEINEAYEVLSDPEK 60
DnaJ cd06257
DnaJ domain or J-domain. DnaJ/Hsp40 (heat shock protein 40) proteins are highly conserved and ...
 7-57 2.24e-26

DnaJ domain or J-domain. DnaJ/Hsp40 (heat shock protein 40) proteins are highly conserved and play crucial roles in protein translation, folding, unfolding, translocation, and degradation. They act primarily by stimulating the ATPase activity of Hsp70s, an important chaperonine family. Hsp40 proteins are characterized by the presence of a J domain, which mediates the interaction with Hsp70. They may contain other domains as well, and the architectures provide a means of classification.


Pssm-ID: 99751 [Multi-domain]  Cd Length: 55  Bit Score: 98.77  E-value: 2.24e-26
                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|....
gi 1913184352   7 YYDILGVKPSASPEEIKKAYRKLALKYHPDKNPDE---GEKFKLISQAYEVLSD 57
Cdd:cd06257     2 YYDILGVPPDASDEEIKKAYRKLALKYHPDKNPDDpeaEEKFKEINEAYEVLSD 55
SEC63 COG5407
Preprotein translocase subunit Sec63 [Intracellular trafficking, secretion, and vesicular ...
 7-61 3.97e-25

Preprotein translocase subunit Sec63 [Intracellular trafficking, secretion, and vesicular transport];


Pssm-ID: 444165 [Multi-domain]  Cd Length: 61  Bit Score: 95.45  E-value: 3.97e-25
                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|....*...
gi 1913184352   7 YYDILGVKPSASPEEIKKAYRKLALKYHPDKNPDEG---EKFKLISQAYEVLSDPKKR 61
Cdd:COG5407     2 PYEVLGVAKTASADEIKKAYRKLAKKYHPDRNKGDPkaeERFKEINEAYELLSDAEKR 59
CbpA COG2214
Curved DNA-binding protein CbpA, contains a DnaJ-like domain [Transcription];
1-71 1.46e-24

Curved DNA-binding protein CbpA, contains a DnaJ-like domain [Transcription];


Pssm-ID: 441816 [Multi-domain]  Cd Length: 91  Bit Score: 95.17  E-value: 1.46e-24
                          10        20        30        40        50        60        70
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 1913184352   1 MVKETQYYDILGVKPSASPEEIKKAYRKLALKYHPDKNPDEG----EKFKLISQAYEVLSDPKKRDVYDQGGEQA 71
Cdd:COG2214     1 MPDLKDHYAVLGVPPDASLEEIRQAYRRLAKLLHPDRGGELKalaeELFQRLNEAYEVLSDPERRAEYDRELGQS 75
PRK14299 PRK14299
chaperone protein DnaJ; Provisional
 7-129 5.26e-23

chaperone protein DnaJ; Provisional


Pssm-ID: 237667 [Multi-domain]  Cd Length: 291  Bit Score: 96.55  E-value: 5.26e-23
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1913184352   7 YYDILGVKPSASPEEIKKAYRKLALKYHPDKNPDEG--EKFKLISQAYEVLSDPKKRDVYDQGGEQAIKEGGS------- 77
Cdd:PRK14299    6 YYAILGVPKNASQDEIKKAFKKLARKYHPDVNKSPGaeEKFKEINEAYTVLSDPEKRRIYDTYGTTAASAGWQgpppgpp 85

                          90       100       110       120       130       140
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 1913184352  78 -----GSPSFSSPMDIFDMFFGGGGRMA-----------RERRGKNVVHQLSVTLEDLYNGVTKKLAL 129
Cdd:PRK14299   86 gggdfSGFNVGDFSDFFQQLFGGRGGFGgfgdlfgsvgrRARKGRDLEAELPLTLEEAYRGGEKVVEV 153
PRK10266 PRK10266
curved DNA-binding protein;
7-118 7.19e-23

curved DNA-binding protein;


Pssm-ID: 182347 [Multi-domain]  Cd Length: 306  Bit Score: 96.43  E-value: 7.19e-23
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1913184352   7 YYDILGVKPSASPEEIKKAYRKLALKYHPD--KNPDEGEKFKLISQAYEVLSDPKKRDVYDQ--------GGEQAIKEGG 76
Cdd:PRK10266    6 YYAIMGVKPTDDLKTIKTAYRRLARKYHPDvsKEPDAEARFKEVAEAWEVLSDEQRRAEYDQlwqhrndpQFNRQFQHGD 85

                          90       100       110       120
                  ....*....|....*....|....*....|....*....|....*
gi 1913184352  77 SGSPSFSSPMDIFDMFFGGGGRMARER---RGKNVVHQLSVTLED 118
Cdd:PRK10266   86 GQSFNAEDFDDIFSSIFGQHARQSRQRpaaRGHDIEIEVAVFLEE 130
DnaJ_CXXCXGXG pfam00684
DnaJ central domain; The central cysteine-rich (CR) domain of DnaJ proteins contains four ...
 135-201 5.68e-20

DnaJ central domain; The central cysteine-rich (CR) domain of DnaJ proteins contains four repeats of the motif CXXCXGXG where X is any amino acid. The isolated cysteine rich domain folds in zinc dependent fashion. Each set of two repeats binds one unit of zinc. Although this domain has been implicated in substrate binding, no evidence of specific interaction between the isolated DNAJ cysteine rich domain and various hydrophobic peptides has been found.


Pssm-ID: 459904 [Multi-domain]  Cd Length: 65  Bit Score: 81.84  E-value: 5.68e-20
                          10        20        30        40        50        60
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 1913184352 135 CEKCEGVGGKKG-SVEKCPLCKGRGMQIHIQQIGPGMVQQiQTVCIECKGQGERInpKDRCESCSGAK 201
Cdd:pfam00684   1 CPTCNGSGAKPGtKPTTCPTCGGTGQVRRVQQTGPGFFQM-QSTCPTCGGTGKII--KDPCKKCKGKG 65
DnaJ_zf cd10719
Zinc finger domain of DnaJ and HSP40; Central/middle or CxxCxGxG-motif containing domain of ...
 135-201 2.32e-18

Zinc finger domain of DnaJ and HSP40; Central/middle or CxxCxGxG-motif containing domain of DnaJ/Hsp40 (heat shock protein 40). DnaJ proteins are highly conserved and play crucial roles in protein translation, folding, unfolding, translocation, and degradation. They act primarily by stimulating the ATPase activity of Hsp70s, an important chaperonin family. Hsp40 proteins are characterized by the presence of an N-terminal J domain, which mediates the interaction with Hsp70. This central domain contains four repeats of a CxxCxGxG motif and binds to two Zinc ions. It has been implicated in substrate binding.


Pssm-ID: 199908 [Multi-domain]  Cd Length: 65  Bit Score: 77.68  E-value: 2.32e-18
                          10        20        30        40        50        60
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 1913184352 135 CEKCEGVGGKKGS-VEKCPLCKGRGMQIHIQQIGpGMVQQIQTVCIECKGQGERInpKDRCESCSGAK 201
Cdd:cd10719     1 CPTCNGSGAKPGTkPKTCPTCGGSGQVRQVQGTG-FGFFQTQTTCPTCGGTGKII--KDPCPKCKGKG 65
DjlA COG1076
DnaJ domain-containing protein [Posttranslational modification, protein turnover, chaperones];
7-63 2.23e-14

DnaJ domain-containing protein [Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 440694 [Multi-domain]  Cd Length: 75  Bit Score: 67.13  E-value: 2.23e-14
                          10        20        30        40        50        60
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 1913184352   7 YYDILGVKPSASPEEIKKAYRKLALKYHPDK----NPDE-----GEKFKLISQAYEVLSDPKKRDV 63
Cdd:COG1076     6 AFELLGLPPDADDAELKRAYRKLQREHHPDRlaagLPEEeqrlaLQKAAAINEAYETLKDPRGIDL 71
PTZ00341 PTZ00341
Ring-infected erythrocyte surface antigen; Provisional
 2-74 1.53e-11

Ring-infected erythrocyte surface antigen; Provisional


Pssm-ID: 173534 [Multi-domain]  Cd Length: 1136  Bit Score: 65.19  E-value: 1.53e-11
                           10        20        30        40        50        60        70
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 1913184352    2 VKETQYYDILGVKPSASPEEIKKAYRKLALKYHPDK-NPDEG-EKFKLISQAYEVLSDPKKRDVYDQGGEQAIKE 74
Cdd:PTZ00341   570 IPDTLFYDILGVGVNADMKEISERYFKLAENYYPPKrSGNEGfHKFKKINEAYQILGDIDKKKMYNKFGYDGIKG 644
ZUO1 COG5269
Ribosome-associated chaperone zuotin [Translation, ribosomal structure and biogenesis / ...
 3-65 6.12e-10

Ribosome-associated chaperone zuotin [Translation, ribosomal structure and biogenesis / Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 227594 [Multi-domain]  Cd Length: 379  Bit Score: 59.66  E-value: 6.12e-10
                          10        20        30        40        50        60        70
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 1913184352   3 KETQYYDILGV---KPSASPEEIKKAYRKLALKYHPDKNPDEGEK-----FKLISQAYEVLSDPKKRDVYD 65
Cdd:COG5269    41 KKVDLYALLGLskyRTKAIPPQILKAHKKKVYKYHPDKTAAGGNKgcdefFKLIQKAREVLGDRKLRLQYD 111
djlA PRK09430
co-chaperone DjlA;
8-55 2.37e-08

co-chaperone DjlA;


Pssm-ID: 236512 [Multi-domain]  Cd Length: 267  Bit Score: 54.05  E-value: 2.37e-08
                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|....*...
gi 1913184352   8 YDILGVKPSASPEEIKKAYRKLALKYHPDK-----NPDE-----GEKFKLISQAYEVL 55
Cdd:PRK09430  203 YKVLGVSESDDDQEIKRAYRKLMSEHHPDKlvakgLPPEmmemaKEKAQEIQAAYELI 260
DnaJ_C cd10747
C-terminal substrate binding domain of DnaJ and HSP40; The C-terminal region of the DnaJ/Hsp40 ...
 106-255 2.69e-07

C-terminal substrate binding domain of DnaJ and HSP40; The C-terminal region of the DnaJ/Hsp40 protein mediates oligomerization and binding to denatured polypeptide substrate. DnaJ/Hsp40 is a widely conserved heat-shock protein. It prevents the aggregation of unfolded substrate and forms a ternary complex with both substrate and DnaK/Hsp70; the N-terminal J-domain of DnaJ/Hsp40 stimulates the ATPase activity of DnaK/Hsp70.


Pssm-ID: 199909 [Multi-domain]  Cd Length: 158  Bit Score: 49.35  E-value: 2.69e-07
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1913184352 106 KNVVHQLSVTLEDLYNGVTKKLALQKNVICEKcegvggkkgsvekcplcKGRGMQIHIQqigPGmVQQIQTVCIEckGQG 185
Cdd:cd10747     1 ADLRYDLELTLEEAYFGKEKEIKIPRKVTRVR-----------------EKKTLTVKIP---AG-VDDGQRLRLR--GEG 57

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1913184352 186 E---------------RINPKDRCEScSGAKVIREKKI----------IEVHVEKGEV-------IKHGDLRCVRDEGMP 233
Cdd:cd10747    58 DagpnggppgdlyvviRVKPHPVFRR-DGNDLYCEVPIslteallggeIEVPTLGGKVklkippgTQPGTVLRLKGKGMP 136

                         170       180
                  ....*....|....*....|..
gi 1913184352 234 IYKaPLEKGILIIQFLVIFPEK 255
Cdd:cd10747   137 RLR-GGGRGDLYVEVKVEFPKK 157
PHA03102 PHA03102
Small T antigen; Reviewed
 9-70 5.72e-05

Small T antigen; Reviewed


Pssm-ID: 222986 [Multi-domain]  Cd Length: 153  Bit Score: 42.74  E-value: 5.72e-05
                          10        20        30        40        50        60
                  ....*....|....*....|....*....|....*....|....*....|....*....|....
gi 1913184352   9 DILGVKPSA--SPEEIKKAYRKLALKYHPDKNPDEgEKFKLISQAYEVLSDPKKRDVYDQGGEQ 70
Cdd:PHA03102    9 DLLGLPRSAwgNLPLMRKAYLRKCLEFHPDKGGDE-EKMKELNTLYKKFRESVKSLRDLDGEED 71
PHA02624 PHA02624
large T antigen; Provisional
 9-61 1.84e-04

large T antigen; Provisional


Pssm-ID: 222912 [Multi-domain]  Cd Length: 647  Bit Score: 43.05  E-value: 1.84e-04
                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|....*
gi 1913184352   9 DILGVKPSA--SPEEIKKAYRKLALKYHPDKNPDEgEKFKLISQAYEVLSDPKKR 61
Cdd:PHA02624   15 DLLGLPMAAwgNLPLMRKAYLRKCKEYHPDKGGDE-EKMKRLNSLYKKLQEGVKS 68
PTZ00100 PTZ00100
DnaJ chaperone protein; Provisional
 5-36 6.60e-04

DnaJ chaperone protein; Provisional


Pssm-ID: 240265  Cd Length: 116  Bit Score: 38.68  E-value: 6.60e-04
                          10        20        30
                  ....*....|....*....|....*....|..
gi 1913184352   5 TQYYDILGVKPSASPEEIKKAYRKLALKYHPD 36
Cdd:PTZ00100   65 SEAYKILNISPTASKERIREAHKQLMLRNHPD 96
hscB PRK01356
co-chaperone HscB; Provisional
 7-64 1.32e-03

co-chaperone HscB; Provisional


Pssm-ID: 167217 [Multi-domain]  Cd Length: 166  Bit Score: 38.70  E-value: 1.32e-03
                          10        20        30        40        50        60
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 1913184352   7 YYDILGVKP--SASPEEIKKAYRKLALKYHPD--KNPDEGEKFKLIS----QAYEVLSDPKKRDVY 64
Cdd:PRK01356    4 YFQLLGLPQeyNIDLKILEKQYFAMQVKYHPDkaKTLQEKEQNLIIAselnNAYSTLKDALKRAEY 69
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
Help | Disclaimer | Write to the Help Desk
NCBI | NLM | NIH