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Conserved domains on  [gi|398365261|ref|NP_011547|]
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Tim21p [Saccharomyces cerevisiae S288C]

Protein Classification

Coa1/Tim21 domain-containing protein; cytochrome c oxidase assembly factor 1 family protein( domain architecture ID 10550651)

Coa1/Tim21 domain-containing protein such as mitochondrial import inner membrane translocase subunit Tim21, an essential component of the TIM23 complex that mediates the translocation of transit peptide-containing proteins across the mitochondrial inner membrane| cytochrome c oxidase assembly factor 1 family protein similar to Saccharomyces cerevisiae cytochrome c oxidase assembly factor 1 that is required for efficient assembly of cytochrome c oxidase in the mitochondrial inner membrane

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
TIM21 pfam08294
TIM21; TIM21 interacts with the outer mitochondrial TOM complex and promotes the insertion of ...
 67-219 6.67e-75

TIM21; TIM21 interacts with the outer mitochondrial TOM complex and promotes the insertion of proteins into the inner mitochondrial membrane.


:

Pssm-ID: 311963  Cd Length: 145  Bit Score: 223.71  E-value: 6.67e-75
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 398365261   67 QVKSASTFTFSGILVIGAVGISAIVIYLILSELFSPSGDTQLFNRAVSMVEKNKDIRSLLqcddgitgKERLKAYGELIT 146
Cdd:pfam08294   1 KVKEATTFTFYFIIVLGGVGVTGLVIYLIFSELFSPSGDTQIFNRAVELVEENERVRDLL--------GERIKAYGEETR 72

                          90       100       110       120       130       140       150
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 398365261  147 NDKWTRNRPIVSTKKLDKEGRTHHYMRFHVESKKKIALVHLEAKESKQNYQPDFINMYVDVPGEKRYYLIKPK 219
Cdd:pfam08294  73 RGRWTRNRPIVSTREYDKDGKEHIRMQFHVEGPRKKGTVHLELVESDDSGQYEFRYLYVDVPGHKRIYLEDNR 145
 
Name Accession Description Interval E-value
TIM21 pfam08294
TIM21; TIM21 interacts with the outer mitochondrial TOM complex and promotes the insertion of ...
 67-219 6.67e-75

TIM21; TIM21 interacts with the outer mitochondrial TOM complex and promotes the insertion of proteins into the inner mitochondrial membrane.


Pssm-ID: 311963  Cd Length: 145  Bit Score: 223.71  E-value: 6.67e-75
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 398365261   67 QVKSASTFTFSGILVIGAVGISAIVIYLILSELFSPSGDTQLFNRAVSMVEKNKDIRSLLqcddgitgKERLKAYGELIT 146
Cdd:pfam08294   1 KVKEATTFTFYFIIVLGGVGVTGLVIYLIFSELFSPSGDTQIFNRAVELVEENERVRDLL--------GERIKAYGEETR 72

                          90       100       110       120       130       140       150
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 398365261  147 NDKWTRNRPIVSTKKLDKEGRTHHYMRFHVESKKKIALVHLEAKESKQNYQPDFINMYVDVPGEKRYYLIKPK 219
Cdd:pfam08294  73 RGRWTRNRPIVSTREYDKDGKEHIRMQFHVEGPRKKGTVHLELVESDDSGQYEFRYLYVDVPGHKRIYLEDNR 145
 
Name Accession Description Interval E-value
TIM21 pfam08294
TIM21; TIM21 interacts with the outer mitochondrial TOM complex and promotes the insertion of ...
 67-219 6.67e-75

TIM21; TIM21 interacts with the outer mitochondrial TOM complex and promotes the insertion of proteins into the inner mitochondrial membrane.


Pssm-ID: 311963  Cd Length: 145  Bit Score: 223.71  E-value: 6.67e-75
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 398365261   67 QVKSASTFTFSGILVIGAVGISAIVIYLILSELFSPSGDTQLFNRAVSMVEKNKDIRSLLqcddgitgKERLKAYGELIT 146
Cdd:pfam08294   1 KVKEATTFTFYFIIVLGGVGVTGLVIYLIFSELFSPSGDTQIFNRAVELVEENERVRDLL--------GERIKAYGEETR 72

                          90       100       110       120       130       140       150
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 398365261  147 NDKWTRNRPIVSTKKLDKEGRTHHYMRFHVESKKKIALVHLEAKESKQNYQPDFINMYVDVPGEKRYYLIKPK 219
Cdd:pfam08294  73 RGRWTRNRPIVSTREYDKDGKEHIRMQFHVEGPRKKGTVHLELVESDDSGQYEFRYLYVDVPGHKRIYLEDNR 145
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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