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Conserved domains on  [gi|33286446|ref|NP_031372|]
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opioid growth factor receptor [Homo sapiens]

Protein Classification

OGFr_N and KLF9_13_N-like domain-containing protein( domain architecture ID 13702710)

OGFr_N and KLF9_13_N-like domain-containing protein

Graphical summary

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List of domain hits

Name Accession Description Interval E-value
OGFr_N pfam04664
Opioid growth factor receptor (OGFr) conserved region; Opioid peptides act as growth factors ...
86-293 1.62e-144

Opioid growth factor receptor (OGFr) conserved region; Opioid peptides act as growth factors in neural and non-neural cells and tissues, in addition to serving in neurotransmission/neuromodulation in the nervous system. The Opioid growth factor receptor is an integral membrane protein associated with the nucleus. The conserved region is situated at the N-terminus of the member proteins with a series of imperfect repeats lying immediately to its C-terminus.


:

Pssm-ID: 461383  Cd Length: 208  Bit Score: 419.04  E-value: 1.62e-144
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 33286446    86 DCNGDTPNLSFYRNEIRFLPNGCFIEDILQNWTDNYDLLEDNHSYIQWLFPLREPGVNWHAKPLTLREVEVFKSSQEIQE 165
Cdd:pfam04664   1 DQPNDMANLKFYKNEIPFQPDGIYIEEFLQKWKGDYDKLEHNHSYIQWLFPLREPGVNWRAKPLTPKEIEAFKKSEEAKR 80
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 33286446   166 RLVRAYELMLGFYGIRLEDRGTGTVGRAQNYQKRFQNLNWRSHNNLRITRILKSLGELGLEHFQAPLVRFFLEETLVRRE 245
Cdd:pfam04664  81 RLLKSYKLMLGFYGIELLDEKTGEVKRASNWQERFQNLNRNSHNNLRITRILKSLGELGYEHYQAPLVRFFLEETLVHFT 160
                         170       180       190       200
                  ....*....|....*....|....*....|....*....|....*...
gi 33286446   246 LPGVRQSALDYFMFAVRCRHQRRQLVHFAWEHFRPRCKFVWGPQDKLR 293
Cdd:pfam04664 161 LPNVKQSALDYFVFTVRDKRERRELVRFAWQHYKPRGKFVWGPWDKLQ 208
PRK07764 super family cl35613
DNA polymerase III subunits gamma and tau; Validated
451-671 6.04e-15

DNA polymerase III subunits gamma and tau; Validated


The actual alignment was detected with superfamily member PRK07764:

Pssm-ID: 236090 [Multi-domain]  Cd Length: 824  Bit Score: 78.49  E-value: 6.04e-15
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 33286446  451 VADKVRKRRKVD-EGAGDSAAVASGGAQTLALAGSPAPSGHPKAGHSENGVEEDTEGRTGPKEGTPGSPSETPGPSPAGP 529
Cdd:PRK07764 574 LAEELGGDWQVEaVVGPAPGAAGGEGPPAPASSGPPEEAARPAAPAAPAAPAAPAPAGAAAAPAEASAAPAPGVAAPEHH 653
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 33286446  530 AGDEPAESPSETPGPRPAGPAGDEPAESPSETPGPRPAGPAGDEPAESPSETPGPSPAGPTRDEPAESPSETPGPRPAGP 609
Cdd:PRK07764 654 PKHVAVPDASDGGDGWPAKAGGAAPAAPPPAPAPAAPAAPAGAAPAQPAPAPAATPPAGQADDPAAQPPQAAQGASAPSP 733
                        170       180       190       200       210       220
                 ....*....|....*....|....*....|....*....|....*....|....*....|..
gi 33286446  610 AGDEPAESPSEtPGPRPAGPAGDEPAESPSETPGPSPAGPTRDEPAKAGEAAELQDAEVESS 671
Cdd:PRK07764 734 AADDPVPLPPE-PDDPPDPAGAPAQPPPPPAPAPAAAPAAAPPPSPPSEEEEMAEDDAPSMD 794
 
Name Accession Description Interval E-value
OGFr_N pfam04664
Opioid growth factor receptor (OGFr) conserved region; Opioid peptides act as growth factors ...
86-293 1.62e-144

Opioid growth factor receptor (OGFr) conserved region; Opioid peptides act as growth factors in neural and non-neural cells and tissues, in addition to serving in neurotransmission/neuromodulation in the nervous system. The Opioid growth factor receptor is an integral membrane protein associated with the nucleus. The conserved region is situated at the N-terminus of the member proteins with a series of imperfect repeats lying immediately to its C-terminus.


Pssm-ID: 461383  Cd Length: 208  Bit Score: 419.04  E-value: 1.62e-144
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 33286446    86 DCNGDTPNLSFYRNEIRFLPNGCFIEDILQNWTDNYDLLEDNHSYIQWLFPLREPGVNWHAKPLTLREVEVFKSSQEIQE 165
Cdd:pfam04664   1 DQPNDMANLKFYKNEIPFQPDGIYIEEFLQKWKGDYDKLEHNHSYIQWLFPLREPGVNWRAKPLTPKEIEAFKKSEEAKR 80
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 33286446   166 RLVRAYELMLGFYGIRLEDRGTGTVGRAQNYQKRFQNLNWRSHNNLRITRILKSLGELGLEHFQAPLVRFFLEETLVRRE 245
Cdd:pfam04664  81 RLLKSYKLMLGFYGIELLDEKTGEVKRASNWQERFQNLNRNSHNNLRITRILKSLGELGYEHYQAPLVRFFLEETLVHFT 160
                         170       180       190       200
                  ....*....|....*....|....*....|....*....|....*...
gi 33286446   246 LPGVRQSALDYFMFAVRCRHQRRQLVHFAWEHFRPRCKFVWGPQDKLR 293
Cdd:pfam04664 161 LPNVKQSALDYFVFTVRDKRERRELVRFAWQHYKPRGKFVWGPWDKLQ 208
PRK07764 PRK07764
DNA polymerase III subunits gamma and tau; Validated
451-671 6.04e-15

DNA polymerase III subunits gamma and tau; Validated


Pssm-ID: 236090 [Multi-domain]  Cd Length: 824  Bit Score: 78.49  E-value: 6.04e-15
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 33286446  451 VADKVRKRRKVD-EGAGDSAAVASGGAQTLALAGSPAPSGHPKAGHSENGVEEDTEGRTGPKEGTPGSPSETPGPSPAGP 529
Cdd:PRK07764 574 LAEELGGDWQVEaVVGPAPGAAGGEGPPAPASSGPPEEAARPAAPAAPAAPAAPAPAGAAAAPAEASAAPAPGVAAPEHH 653
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 33286446  530 AGDEPAESPSETPGPRPAGPAGDEPAESPSETPGPRPAGPAGDEPAESPSETPGPSPAGPTRDEPAESPSETPGPRPAGP 609
Cdd:PRK07764 654 PKHVAVPDASDGGDGWPAKAGGAAPAAPPPAPAPAAPAAPAGAAPAQPAPAPAATPPAGQADDPAAQPPQAAQGASAPSP 733
                        170       180       190       200       210       220
                 ....*....|....*....|....*....|....*....|....*....|....*....|..
gi 33286446  610 AGDEPAESPSEtPGPRPAGPAGDEPAESPSETPGPSPAGPTRDEPAKAGEAAELQDAEVESS 671
Cdd:PRK07764 734 AADDPVPLPPE-PDDPPDPAGAPAQPPPPPAPAPAAAPAAAPPPSPPSEEEEMAEDDAPSMD 794
gly_rich_SclB NF038329
LPXTG-anchored collagen-like adhesin Scl2/SclB; SclB (or Scl2 - streptococcal collagen-like ...
456-658 5.12e-07

LPXTG-anchored collagen-like adhesin Scl2/SclB; SclB (or Scl2 - streptococcal collagen-like protein 2) is an LPXTG-anchored surface-anchored adhesin with a variable-length region of triple helix-forming collagen-like Gly-Xaa-Xaa repeats.


Pssm-ID: 468478 [Multi-domain]  Cd Length: 440  Bit Score: 52.60  E-value: 5.12e-07
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 33286446  456 RKRRKVDEGAGDSAAVASGGAQTLALAGSPAPSGHPKAGHSENGvEEDTEGRTGPK--EGTPGSPSETPGPSPAGPAGDE 533
Cdd:NF038329 101 SYLEELDEGLQQLKGDGEKGEPGPAGPAGPAGEQGPRGDRGETG-PAGPAGPPGPQgeRGEKGPAGPQGEAGPQGPAGKD 179
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 33286446  534 PAESPSETPGprPAGPAGDEPAESPSETPGPR-PAGPAGDEPAESPSETPGPSPAGPTRDEPAESPSETPGPR-PAGPAG 611
Cdd:NF038329 180 GEAGAKGPAG--EKGPQGPRGETGPAGEQGPAgPAGPDGEAGPAGEDGPAGPAGDGQQGPDGDPGPTGEDGPQgPDGPAG 257
                        170       180       190       200
                 ....*....|....*....|....*....|....*....|....*..
gi 33286446  612 DEPAESPSETPGprPAGPAGDEPAESPSETPGPSPAGPTRDEPAKAG 658
Cdd:NF038329 258 KDGPRGDRGEAG--PDGPDGKDGERGPVGPAGKDGQNGKDGLPGKDG 302
SepH NF040712
septation protein SepH; Septation protein H (SepH) was firstly characterized in Streptomyces ...
512-661 9.36e-07

septation protein SepH; Septation protein H (SepH) was firstly characterized in Streptomyces venezuelae, and homologs were identified in Mycobacterium smegmatis. SepH contains a N-terminal DUF3071 domain and a conserved C-terminal region. It binds directly to cell division protein FtsZ to stimulate the assembly of FtsZ protofilaments.


Pssm-ID: 468676 [Multi-domain]  Cd Length: 346  Bit Score: 51.31  E-value: 9.36e-07
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 33286446  512 EGTPGSP--SETPGPSPAGPAGDEPAESPSETPGPRPAgpagdePAESPSETPGPRPAGPAGDEPAESPSETPGPSPAGP 589
Cdd:NF040712 189 DPDFGRPlrPLATVPRLAREPADARPEEVEPAPAAEGA------PATDSDPAEAGTPDDLASARRRRAGVEQPEDEPVGP 262
                         90       100       110       120       130       140       150
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 33286446  590 TRDEPAESPSETPGPRPagPAGDEPAESPSETPGPRPAGPAGDEPAESPSETPGPSPAGPTRDEPAKAGEAA 661
Cdd:NF040712 263 GAAPAAEPDEATRDAGE--PPAPGAAETPEAAEPPAPAPAAPAAPAAPEAEEPARPEPPPAPKPKRRRRRAS 332
Herpes_BLLF1 pfam05109
Herpes virus major outer envelope glycoprotein (BLLF1); This family consists of the BLLF1 ...
503-650 1.03e-06

Herpes virus major outer envelope glycoprotein (BLLF1); This family consists of the BLLF1 viral late glycoprotein, also termed gp350/220. It is the most abundantly expressed glycoprotein in the viral envelope of the Herpesviruses and is the major antigen responsible for stimulating the production of neutralising antibodies in vivo.


Pssm-ID: 282904 [Multi-domain]  Cd Length: 886  Bit Score: 52.23  E-value: 1.03e-06
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 33286446   503 DTEGRTGPKEgTPGSPSETPGPSP-AGPAGDEPAESPSETPGPRPAGPAGDEPAESPSetPGPRPAGPAGDEP-AESPSE 580
Cdd:pfam05109 435 NTTGFAAPNT-TTGLPSSTHVPTNlTAPASTGPTVSTADVTSPTPAGTTSGASPVTPS--PSPRDNGTESKAPdMTSPTS 511
                          90       100       110       120       130       140       150
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 33286446   581 ---TPGPSPAGPTrdePAESpseTPGPRPAGPA-GDEPAESPSETPGPRPAGPAgdePAESpseTPGPSPAGPT 650
Cdd:pfam05109 512 avtTPTPNATSPT---PAVT---TPTPNATSPTlGKTSPTSAVTTPTPNATSPT---PAVT---TPTPNATIPT 573
SPT5 COG5164
Transcription elongation factor SPT5 [Transcription];
483-658 1.43e-06

Transcription elongation factor SPT5 [Transcription];


Pssm-ID: 444063 [Multi-domain]  Cd Length: 495  Bit Score: 51.18  E-value: 1.43e-06
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 33286446 483 GSPAPSGHPKAGHSENGVEEDTEGRTGPKEGTPGSPSETPGPSpAGPAGDEPAESPS-ETPGPRPAG------PAGDEPA 555
Cdd:COG5164   2 GLYGPGKTGPSDPGGVTTPAGSQGSTKPAQNQGSTRPAGNTGG-TRPAQNQGSTTPAgNTGGTRPAGnqgatgPAQNQGG 80
                        90       100       110       120       130       140       150       160
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 33286446 556 ESPSETPG-PRPAG------PAGDEPAESPSETPGpsPAGPTRDEPAESPSETPGPRPAGPAGDEPAESPSETPG--PRP 626
Cdd:COG5164  81 TTPAQNQGgTRPAGntggttPAGDGGATGPPDDGG--ATGPPDDGGSTTPPSGGSTTPPGDGGSTPPGPGSTGPGgsTTP 158
                       170       180       190
                ....*....|....*....|....*....|..
gi 33286446 627 AGPAGDEPAESPSETPGPSPAGPTRDEPAKAG 658
Cdd:COG5164 159 PGDGGSTTPPGPGGSTTPPDDGGSTTPPNKGE 190
SepH NF040712
septation protein SepH; Septation protein H (SepH) was firstly characterized in Streptomyces ...
508-651 3.34e-06

septation protein SepH; Septation protein H (SepH) was firstly characterized in Streptomyces venezuelae, and homologs were identified in Mycobacterium smegmatis. SepH contains a N-terminal DUF3071 domain and a conserved C-terminal region. It binds directly to cell division protein FtsZ to stimulate the assembly of FtsZ protofilaments.


Pssm-ID: 468676 [Multi-domain]  Cd Length: 346  Bit Score: 49.77  E-value: 3.34e-06
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 33286446  508 TGPKEGTPGSPSETPGPSPAGPAGDEPAespsETPGPRPAGPAGDEPAESPSETPGPRPAGPAGDEPAESPSETPGPSPA 587
Cdd:NF040712 193 GRPLRPLATVPRLAREPADARPEEVEPA----PAAEGAPATDSDPAEAGTPDDLASARRRRAGVEQPEDEPVGPGAAPAA 268
                         90       100       110       120       130       140
                 ....*....|....*....|....*....|....*....|....*....|....*....|....
gi 33286446  588 GPTRDEPAESPSETPGPRPAGPAGDEPAESPSetPGPRPAGPAGDEPAEsPSETPGPSPAGPTR 651
Cdd:NF040712 269 EPDEATRDAGEPPAPGAAETPEAAEPPAPAPA--APAAPAAPEAEEPAR-PEPPPAPKPKRRRR 329
SAV_2336_NTERM NF041121
SAV_2336 family N-terminal domain; This HMM describes an N-terminal domain shared by SAV_2336 ...
514-606 2.85e-05

SAV_2336 family N-terminal domain; This HMM describes an N-terminal domain shared by SAV_2336 (BAC70047.1) whose C-terminal region suggests restriction enzyme activity (PMID: 18456708), and with other proteins with unrelated C-terminal regions. A member protein was also identified in a kanamycin biosynthetic gene cluster (PMID:16766657), while N-terminal regions of two other member proteins were named Trypco1 in a bioinformatic study (PMID:32101166) of predicted bacterial conflict systems.


Pssm-ID: 469044 [Multi-domain]  Cd Length: 473  Bit Score: 46.92  E-value: 2.85e-05
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 33286446  514 TPGSPSETPGPSPAGPAGDEPAESPSETPGPRPAGPAGDEPAESPSETPGPRPAGPAGDepaesPSETPGPSPAGPTRDE 593
Cdd:NF041121  15 MGRAAAPPSPEGPAPTAASQPATPPPPAAPPSPPGDPPEPPAPEPAPLPAPYPGSLAPP-----PPPPPGPAGAAPGAAL 89
                         90
                 ....*....|...
gi 33286446  594 PAESPSETPGPRP 606
Cdd:NF041121  90 PVRVPAPPALPNP 102
KLF14_N cd21576
N-terminal domain of Kruppel-like factor 14; Kruppel-like factor 14 (KLF14; also known as ...
485-630 4.38e-05

N-terminal domain of Kruppel-like factor 14; Kruppel-like factor 14 (KLF14; also known as Krueppel-like factor 14 or basic transcription element-binding protein 5/BTEB5) is a protein that in humans is encoded by the KLF14 gene. KLF14 regulates the transcription of various genes, including TGFbetaRII (the type II receptor for TGFbeta). KLF14 is expressed in many tissues, lacks introns, and is subject to parent-specific expression. It also appears to be a master regulator of gene expression in adipose tissue. KLF14 is associated with coronary artery disease, hypercholesterolemia, and type 2 diabetes. KLF9, KLF10, KLF11, KLF13, KLF14, and KLF16 share a conserved alpha-helical motif AA/VXXL that mediates their binding to Sin3A and their activities as transcriptional repressors. KLF14 belongs to a family of proteins, called the Specificity Protein (SP)/KLF family, characterized by a C-terminal DNA-binding domain of 81 amino acids consisting of three Kruppel-like C2H2 zinc fingers. These factors bind to a loose consensus motif, namely NNRCRCCYY (where N is any nucleotide; R is A/G, and Y is C/T), such as the recurring motifs in GC and GT boxes (5'-GGGGCGGGG-3' and 5-GGTGTGGGG-3') that are present in promoters and more distal regulatory elements of mammalian genes. Members of the KLF family can act as activators or repressors of transcription depending on cell and promoter context. KLFs regulate various cellular functions, such as proliferation, differentiation, and apoptosis, as well as the development and homeostasis of several types of tissue. In addition to the C-terminal DNA-binding domain, each KLF also has a unique N-terminal activation/repression domain that confers specificity and allows it to bind specifically to a certain partner, leading to distinct activities in vivo. This model represents the N-terminal domain of KLF14.


Pssm-ID: 409238 [Multi-domain]  Cd Length: 195  Bit Score: 44.81  E-value: 4.38e-05
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 33286446 485 PAPSGHPKAGHSENGVEEDTEGRTGPkeGTPGSPSETPGPSPAGPAGDEPAESP-------------------SETPGPR 545
Cdd:cd21576  29 PDPEGAGGAAGSEVGAAPPESALPGP--GPPGPAWVPPLLQVPAPSPGAGGAAPhllaasvladlrggagegsREDSGEA 106
                        90       100       110       120       130       140       150       160
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 33286446 546 P-AGPAGDEPAESPSETPGPRPAGPAGDEPAESPSETPGpSPAGPTRDEPAESPSEtPGPRPAGPAGDEPAESPSETPGP 624
Cdd:cd21576 107 PrASSGSSDPARGSSPTLGSEPAPASGEDAVSGPESSFG-APAIPSAPAAPGAPAV-SGEVPGGAPGAGPAPAAGPAPRR 184

                ....*.
gi 33286446 625 RPAGPA 630
Cdd:cd21576 185 RPVTPA 190
SAV_2336_NTERM NF041121
SAV_2336 family N-terminal domain; This HMM describes an N-terminal domain shared by SAV_2336 ...
563-651 5.36e-05

SAV_2336 family N-terminal domain; This HMM describes an N-terminal domain shared by SAV_2336 (BAC70047.1) whose C-terminal region suggests restriction enzyme activity (PMID: 18456708), and with other proteins with unrelated C-terminal regions. A member protein was also identified in a kanamycin biosynthetic gene cluster (PMID:16766657), while N-terminal regions of two other member proteins were named Trypco1 in a bioinformatic study (PMID:32101166) of predicted bacterial conflict systems.


Pssm-ID: 469044 [Multi-domain]  Cd Length: 473  Bit Score: 46.15  E-value: 5.36e-05
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 33286446  563 GPRPAGPAGDEPAESPSETPGPSPAGPTRDEPAESPSETPGPRPAGPAGDEPAESPSE---TPGPRPAGPAGDEPAESPS 639
Cdd:NF041121  16 GRAAAPPSPEGPAPTAASQPATPPPPAAPPSPPGDPPEPPAPEPAPLPAPYPGSLAPPpppPPGPAGAAPGAALPVRVPA 95
                         90
                 ....*....|..
gi 33286446  640 ETPGPSPAGPTR 651
Cdd:NF041121  96 PPALPNPLELAR 107
SepH NF040712
septation protein SepH; Septation protein H (SepH) was firstly characterized in Streptomyces ...
523-677 5.58e-05

septation protein SepH; Septation protein H (SepH) was firstly characterized in Streptomyces venezuelae, and homologs were identified in Mycobacterium smegmatis. SepH contains a N-terminal DUF3071 domain and a conserved C-terminal region. It binds directly to cell division protein FtsZ to stimulate the assembly of FtsZ protofilaments.


Pssm-ID: 468676 [Multi-domain]  Cd Length: 346  Bit Score: 45.91  E-value: 5.58e-05
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 33286446  523 GPSPAGPAgdepaesPSETPGPRPAGPAGDEPAESPSETPGPRPAgpagdePAESPSETPGPSPAGPTRDEPAESPSETP 602
Cdd:NF040712 189 DPDFGRPL-------RPLATVPRLAREPADARPEEVEPAPAAEGA------PATDSDPAEAGTPDDLASARRRRAGVEQP 255
                         90       100       110       120       130       140       150
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 33286446  603 GPRPAGPAGDEPAESPSETPGPRPAGPAGDEPAESPSETPGPSPAGPTRD-EPAKAGEAAELQDAEVESSAKSGKP 677
Cdd:NF040712 256 EDEPVGPGAAPAAEPDEATRDAGEPPAPGAAETPEAAEPPAPAPAAPAAPaAPEAEEPARPEPPPAPKPKRRRRRA 331
SAV_2336_NTERM NF041121
SAV_2336 family N-terminal domain; This HMM describes an N-terminal domain shared by SAV_2336 ...
535-626 1.15e-04

SAV_2336 family N-terminal domain; This HMM describes an N-terminal domain shared by SAV_2336 (BAC70047.1) whose C-terminal region suggests restriction enzyme activity (PMID: 18456708), and with other proteins with unrelated C-terminal regions. A member protein was also identified in a kanamycin biosynthetic gene cluster (PMID:16766657), while N-terminal regions of two other member proteins were named Trypco1 in a bioinformatic study (PMID:32101166) of predicted bacterial conflict systems.


Pssm-ID: 469044 [Multi-domain]  Cd Length: 473  Bit Score: 44.99  E-value: 1.15e-04
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 33286446  535 AESPSETPGPRPAGPAGDEPAESPSETPGPRPAGPAGDEPAESPSETPGPSPAGPTRDepaesPSETPGPRPAGPAGDEP 614
Cdd:NF041121  16 GRAAAPPSPEGPAPTAASQPATPPPPAAPPSPPGDPPEPPAPEPAPLPAPYPGSLAPP-----PPPPPGPAGAAPGAALP 90
                         90
                 ....*....|..
gi 33286446  615 AESPSETPGPRP 626
Cdd:NF041121  91 VRVPAPPALPNP 102
PspC_subgroup_2 NF033839
pneumococcal surface protein PspC, LPXTG-anchored form; The pneumococcal surface protein PspC, ...
484-677 1.41e-04

pneumococcal surface protein PspC, LPXTG-anchored form; The pneumococcal surface protein PspC, as described in Streptococcus pneumoniae, is a repetitive and highly variable protein, recognized by a conserved N-terminal domain and also by genomic location. This form, subgroup 2, is anchored covalently after cleavage by sortase at a C-terminal LPXTG site. The other form, subgroup 1, has variable numbers of a choline-binding repeat in the C-terminal region, and is also known as choline-binding protein A.


Pssm-ID: 468202 [Multi-domain]  Cd Length: 557  Bit Score: 45.14  E-value: 1.41e-04
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 33286446  484 SPAPSGHPKAGHSENGV--EEDTEGRTGPKEGTPGSPSETPGPSPAGPAGDEPAES--PSETPGPRPAGPAGDEPAESPS 559
Cdd:NF033839 283 TPKEPGNKKPSAPKPGMqpSPQPEKKEVKPEPETPKPEVKPQLEKPKPEVKPQPEKpkPEVKPQLETPKPEVKPQPEKPK 362
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 33286446  560 ETPGPRPAGPAGDEPAE----SPSETPGPSPAGPTRDEPAESPSETPGPRPAGPagdepaeSPSETPGPRPAGPAGDEPA 635
Cdd:NF033839 363 PEVKPQPEKPKPEVKPQpetpKPEVKPQPEKPKPEVKPQPEKPKPEVKPQPEKP-------KPEVKPQPEKPKPEVKPQP 435
                        170       180       190       200
                 ....*....|....*....|....*....|....*....|..
gi 33286446  636 ESPSETPGPSPAGPTRDEPAKageaAELQDAEVESSAKSGKP 677
Cdd:NF033839 436 EKPKPEVKPQPEKPKPEVKPQ----PETPKPEVKPQPEKPKP 473
SAV_2336_NTERM NF041121
SAV_2336 family N-terminal domain; This HMM describes an N-terminal domain shared by SAV_2336 ...
575-666 2.03e-04

SAV_2336 family N-terminal domain; This HMM describes an N-terminal domain shared by SAV_2336 (BAC70047.1) whose C-terminal region suggests restriction enzyme activity (PMID: 18456708), and with other proteins with unrelated C-terminal regions. A member protein was also identified in a kanamycin biosynthetic gene cluster (PMID:16766657), while N-terminal regions of two other member proteins were named Trypco1 in a bioinformatic study (PMID:32101166) of predicted bacterial conflict systems.


Pssm-ID: 469044 [Multi-domain]  Cd Length: 473  Bit Score: 44.22  E-value: 2.03e-04
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 33286446  575 AESPSETPGPSPAGPTRDEPAESPSETPGPRPAGPAGDEPAESPSETPGPRPAGPAGDepaesPSETPGPSPAGPTRDEP 654
Cdd:NF041121  16 GRAAAPPSPEGPAPTAASQPATPPPPAAPPSPPGDPPEPPAPEPAPLPAPYPGSLAPP-----PPPPPGPAGAAPGAALP 90
                         90
                 ....*....|..
gi 33286446  655 AKAGEAAELQDA 666
Cdd:NF041121  91 VRVPAPPALPNP 102
SepH NF040712
septation protein SepH; Septation protein H (SepH) was firstly characterized in Streptomyces ...
486-633 2.46e-04

septation protein SepH; Septation protein H (SepH) was firstly characterized in Streptomyces venezuelae, and homologs were identified in Mycobacterium smegmatis. SepH contains a N-terminal DUF3071 domain and a conserved C-terminal region. It binds directly to cell division protein FtsZ to stimulate the assembly of FtsZ protofilaments.


Pssm-ID: 468676 [Multi-domain]  Cd Length: 346  Bit Score: 43.99  E-value: 2.46e-04
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 33286446  486 APSGHPKAGHSENGVEEDTEGRTGpkEGTPGSPSET-PGPSPAGPAGDEPAESPSETPGPRPAGPAGDEPAESPSETPGP 564
Cdd:NF040712 200 ATVPRLAREPADARPEEVEPAPAA--EGAPATDSDPaEAGTPDDLASARRRRAGVEQPEDEPVGPGAAPAAEPDEATRDA 277
                         90       100       110       120       130       140
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 33286446  565 RPAGPAGDEPAESPSETPGPSPAGPtrdEPAESPSETPGPRPAgpagdEPAESPSETPGPRPAGPAGDE 633
Cdd:NF040712 278 GEPPAPGAAETPEAAEPPAPAPAAP---AAPAAPEAEEPARPE-----PPPAPKPKRRRRRASVPSWDD 338
SAV_2336_NTERM NF041121
SAV_2336 family N-terminal domain; This HMM describes an N-terminal domain shared by SAV_2336 ...
503-591 2.48e-03

SAV_2336 family N-terminal domain; This HMM describes an N-terminal domain shared by SAV_2336 (BAC70047.1) whose C-terminal region suggests restriction enzyme activity (PMID: 18456708), and with other proteins with unrelated C-terminal regions. A member protein was also identified in a kanamycin biosynthetic gene cluster (PMID:16766657), while N-terminal regions of two other member proteins were named Trypco1 in a bioinformatic study (PMID:32101166) of predicted bacterial conflict systems.


Pssm-ID: 469044 [Multi-domain]  Cd Length: 473  Bit Score: 40.76  E-value: 2.48e-03
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 33286446  503 DTEGRTGPKEGTPGSPSETPGPSPAGPAGDEPAESPSETPGPRPAGPAGDEPAESPSeTPGPRPAGPAGDEPAESPSETP 582
Cdd:NF041121  20 APPSPEGPAPTAASQPATPPPPAAPPSPPGDPPEPPAPEPAPLPAPYPGSLAPPPPP-PPGPAGAAPGAALPVRVPAPPA 98

                 ....*....
gi 33286446  583 GPSPAGPTR 591
Cdd:NF041121  99 LPNPLELAR 107
PspC_subgroup_2 NF033839
pneumococcal surface protein PspC, LPXTG-anchored form; The pneumococcal surface protein PspC, ...
483-637 4.00e-03

pneumococcal surface protein PspC, LPXTG-anchored form; The pneumococcal surface protein PspC, as described in Streptococcus pneumoniae, is a repetitive and highly variable protein, recognized by a conserved N-terminal domain and also by genomic location. This form, subgroup 2, is anchored covalently after cleavage by sortase at a C-terminal LPXTG site. The other form, subgroup 1, has variable numbers of a choline-binding repeat in the C-terminal region, and is also known as choline-binding protein A.


Pssm-ID: 468202 [Multi-domain]  Cd Length: 557  Bit Score: 40.14  E-value: 4.00e-03
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 33286446  483 GSPAPSGHPKAGHSENGVEEDTEGRTGPKEGTPGSPSETPGPSPAGPAGD--EPAESPSETPGPRPAGPagdepaeSPSE 560
Cdd:NF033839 348 ETPKPEVKPQPEKPKPEVKPQPEKPKPEVKPQPETPKPEVKPQPEKPKPEvkPQPEKPKPEVKPQPEKP-------KPEV 420
                         90       100       110       120       130       140       150
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 33286446  561 TPGPRPAGPAGDEPAESPSETPGPSPAGPTRDEPAESPSETPGPRPAgPAGDEPAESPS-ETPGPRPAGPAGDEPAES 637
Cdd:NF033839 421 KPQPEKPKPEVKPQPEKPKPEVKPQPEKPKPEVKPQPETPKPEVKPQ-PEKPKPEVKPQpEKPKPDNSKPQADDKKPS 497
PspC_subgroup_2 NF033839
pneumococcal surface protein PspC, LPXTG-anchored form; The pneumococcal surface protein PspC, ...
502-653 4.59e-03

pneumococcal surface protein PspC, LPXTG-anchored form; The pneumococcal surface protein PspC, as described in Streptococcus pneumoniae, is a repetitive and highly variable protein, recognized by a conserved N-terminal domain and also by genomic location. This form, subgroup 2, is anchored covalently after cleavage by sortase at a C-terminal LPXTG site. The other form, subgroup 1, has variable numbers of a choline-binding repeat in the C-terminal region, and is also known as choline-binding protein A.


Pssm-ID: 468202 [Multi-domain]  Cd Length: 557  Bit Score: 40.14  E-value: 4.59e-03
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 33286446  502 EDTEGRTGPKEGTPGSPSETPGPSPAGPAGDEpAESPSETPGPRPAGPAGDEPAESPSETPGPRPAGPagdepaeSPSET 581
Cdd:NF033839 350 PKPEVKPQPEKPKPEVKPQPEKPKPEVKPQPE-TPKPEVKPQPEKPKPEVKPQPEKPKPEVKPQPEKP-------KPEVK 421
                         90       100       110       120       130       140       150
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 33286446  582 PGPSPAGPTRDEPAESPSETPGPRPAGPAGDEPAESPSETPGPRPAgPAGDEPAESPS-ETPGPSPAGPTRDE 653
Cdd:NF033839 422 PQPEKPKPEVKPQPEKPKPEVKPQPEKPKPEVKPQPETPKPEVKPQ-PEKPKPEVKPQpEKPKPDNSKPQADD 493
PspC_subgroup_1 NF033838
pneumococcal surface protein PspC, choline-binding form; The pneumococcal surface protein PspC, ...
572-658 6.91e-03

pneumococcal surface protein PspC, choline-binding form; The pneumococcal surface protein PspC, as described in Streptococcus pneumoniae, is a repetitive and highly variable protein, recognized by a conserved N-terminal domain and also by genomic location. This form, subgroup 1, has variable numbers of a choline-binding repeat in the C-terminal region, and is also known as choline-binding protein A. The other form, subgroup 2, is anchored covalently after cleavage by sortase at a C-terminal LPXTG site.


Pssm-ID: 468201 [Multi-domain]  Cd Length: 684  Bit Score: 39.61  E-value: 6.91e-03
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 33286446  572 DEPAESPSETPGPSPAgptrdePAespSETPGPRPAGPAGDEPAESPSETPGPRP-AGPAGDEPAESPSETPgPSPAGPT 650
Cdd:NF033838 410 DKVKEKPAEQPQPAPA------PQ---PEKPAPKPEKPAEQPKAEKPADQQAEEDyARRSEEEYNRLTQQQP-PKTEKPA 479

                 ....*...
gi 33286446  651 RDEPAKAG 658
Cdd:NF033838 480 QPSTPKTG 487
rad23 TIGR00601
UV excision repair protein Rad23; All proteins in this family for which functions are known ...
544-623 9.52e-03

UV excision repair protein Rad23; All proteins in this family for which functions are known are components of a multiprotein complex used for targeting nucleotide excision repair to specific parts of the genome. In humans, Rad23 complexes with the XPC protein. This family is based on the phylogenomic analysis of JA Eisen (1999, Ph.D. Thesis, Stanford University). [DNA metabolism, DNA replication, recombination, and repair]


Pssm-ID: 273167 [Multi-domain]  Cd Length: 378  Bit Score: 38.72  E-value: 9.52e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 33286446   544 PRPAGPAGDEPAESPSETPGPRPAGPAgdepaeSPSETPGPSPAGpTRDEPAESPSETPGPRPAGPAGDEPAESPSETPG 623
Cdd:TIGR00601  77 PKTGTGKVAPPAATPTSAPTPTPSPPA------SPASGMSAAPAS-AVEEKSPSEESATATAPESPSTSVPSSGSDAAST 149
 
Name Accession Description Interval E-value
OGFr_N pfam04664
Opioid growth factor receptor (OGFr) conserved region; Opioid peptides act as growth factors ...
86-293 1.62e-144

Opioid growth factor receptor (OGFr) conserved region; Opioid peptides act as growth factors in neural and non-neural cells and tissues, in addition to serving in neurotransmission/neuromodulation in the nervous system. The Opioid growth factor receptor is an integral membrane protein associated with the nucleus. The conserved region is situated at the N-terminus of the member proteins with a series of imperfect repeats lying immediately to its C-terminus.


Pssm-ID: 461383  Cd Length: 208  Bit Score: 419.04  E-value: 1.62e-144
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 33286446    86 DCNGDTPNLSFYRNEIRFLPNGCFIEDILQNWTDNYDLLEDNHSYIQWLFPLREPGVNWHAKPLTLREVEVFKSSQEIQE 165
Cdd:pfam04664   1 DQPNDMANLKFYKNEIPFQPDGIYIEEFLQKWKGDYDKLEHNHSYIQWLFPLREPGVNWRAKPLTPKEIEAFKKSEEAKR 80
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 33286446   166 RLVRAYELMLGFYGIRLEDRGTGTVGRAQNYQKRFQNLNWRSHNNLRITRILKSLGELGLEHFQAPLVRFFLEETLVRRE 245
Cdd:pfam04664  81 RLLKSYKLMLGFYGIELLDEKTGEVKRASNWQERFQNLNRNSHNNLRITRILKSLGELGYEHYQAPLVRFFLEETLVHFT 160
                         170       180       190       200
                  ....*....|....*....|....*....|....*....|....*...
gi 33286446   246 LPGVRQSALDYFMFAVRCRHQRRQLVHFAWEHFRPRCKFVWGPQDKLR 293
Cdd:pfam04664 161 LPNVKQSALDYFVFTVRDKRERRELVRFAWQHYKPRGKFVWGPWDKLQ 208
PRK07764 PRK07764
DNA polymerase III subunits gamma and tau; Validated
451-671 6.04e-15

DNA polymerase III subunits gamma and tau; Validated


Pssm-ID: 236090 [Multi-domain]  Cd Length: 824  Bit Score: 78.49  E-value: 6.04e-15
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 33286446  451 VADKVRKRRKVD-EGAGDSAAVASGGAQTLALAGSPAPSGHPKAGHSENGVEEDTEGRTGPKEGTPGSPSETPGPSPAGP 529
Cdd:PRK07764 574 LAEELGGDWQVEaVVGPAPGAAGGEGPPAPASSGPPEEAARPAAPAAPAAPAAPAPAGAAAAPAEASAAPAPGVAAPEHH 653
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 33286446  530 AGDEPAESPSETPGPRPAGPAGDEPAESPSETPGPRPAGPAGDEPAESPSETPGPSPAGPTRDEPAESPSETPGPRPAGP 609
Cdd:PRK07764 654 PKHVAVPDASDGGDGWPAKAGGAAPAAPPPAPAPAAPAAPAGAAPAQPAPAPAATPPAGQADDPAAQPPQAAQGASAPSP 733
                        170       180       190       200       210       220
                 ....*....|....*....|....*....|....*....|....*....|....*....|..
gi 33286446  610 AGDEPAESPSEtPGPRPAGPAGDEPAESPSETPGPSPAGPTRDEPAKAGEAAELQDAEVESS 671
Cdd:PRK07764 734 AADDPVPLPPE-PDDPPDPAGAPAQPPPPPAPAPAAAPAAAPPPSPPSEEEEMAEDDAPSMD 794
PHA03247 PHA03247
large tegument protein UL36; Provisional
287-655 2.13e-14

large tegument protein UL36; Provisional


Pssm-ID: 223021 [Multi-domain]  Cd Length: 3151  Bit Score: 77.29  E-value: 2.13e-14
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 33286446   287 GPQDKLRRFKPSSLPHPLEGSRKVEEEGSPGDPDHEASTQGRTCGPEHSKGGGRvDEGPQPRSVEPQDAGPLERSQGDEA 366
Cdd:PHA03247 2579 EPAVTSRARRPDAPPQSARPRAPVDDRGDPRGPAPPSPLPPDTHAPDPPPPSPS-PAANEPDPHPPPTVPPPERPRDDPA 2657
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 33286446   367 GGHGEDR---------PEPLSPKESKKRK---------LELSRREQPPTEPGPQSASEVEKIALNLEGCALSQGSLRTGT 428
Cdd:PHA03247 2658 PGRVSRPrrarrlgraAQASSPPQRPRRRaarptvgslTSLADPPPPPPTPEPAPHALVSATPLPPGPAAARQASPALPA 2737
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 33286446   429 QEV------GGQDPGEAVQPCRQPL--GARVADKVRKRRKVDEGAGDSAAVASGGAQTLALAGSPAPSGHPKAGHSENGV 500
Cdd:PHA03247 2738 APAppavpaGPATPGGPARPARPPTtaGPPAPAPPAAPAAGPPRRLTRPAVASLSESRESLPSPWDPADPPAAVLAPAAA 2817
                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 33286446   501 EEDTEGRTG----PKEGTPGSPSETPGPSPA--------GPAGD----EPAESPSETPGPRPAGPAGDEPAESPSETPGP 564
Cdd:PHA03247 2818 LPPAASPAGplppPTSAQPTAPPPPPGPPPPslplggsvAPGGDvrrrPPSRSPAAKPAAPARPPVRRLARPAVSRSTES 2897
                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 33286446   565 RPAGPAGDEPAESPSETPGPSPAGPTRDEPAESPSETPGPRPAGPAgdEPAESPSETPGPRPAGPAGDEPAESPSETPGP 644
Cdd:PHA03247 2898 FALPPDQPERPPQPQAPPPPQPQPQPPPPPQPQPPPPPPPRPQPPL--APTTDPAGAGEPSGAVPQPWLGALVPGRVAVP 2975
                         410
                  ....*....|....*
gi 33286446   645 ----SPAGPTRDEPA 655
Cdd:PHA03247 2976 rfrvPQPAPSREAPA 2990
PRK07003 PRK07003
DNA polymerase III subunit gamma/tau;
470-661 5.37e-14

DNA polymerase III subunit gamma/tau;


Pssm-ID: 235906 [Multi-domain]  Cd Length: 830  Bit Score: 75.66  E-value: 5.37e-14
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 33286446  470 AVASGGAqTLALAGSPAPSGHPKAGHSENGVEEDTEgrTGPKEGTPGSPSETPGPSPAGPAGDEPAESPSETPGPRPAGP 549
Cdd:PRK07003 361 AVTGGGA-PGGGVPARVAGAVPAPGARAAAAVGASA--VPAVTAVTGAAGAALAPKAAAAAAATRAEAPPAAPAPPATAD 437
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 33286446  550 AGDEPAESPSETPGPRPAGPAGDEPAESPSETPGPSP---AGPTRDEPAESPSEtPGPRPAGPAgdEPAESPSETPGPRP 626
Cdd:PRK07003 438 RGDDAADGDAPVPAKANARASADSRCDERDAQPPADSgsaSAPASDAPPDAAFE-PAPRAAAPS--AATPAAVPDARAPA 514
                        170       180       190
                 ....*....|....*....|....*....|....*.
gi 33286446  627 AGPAGDEPAESPSETPGPSPAGPTRDEP-AKAGEAA 661
Cdd:PRK07003 515 AASREDAPAAAAPPAPEARPPTPAAAAPaARAGGAA 550
PRK07764 PRK07764
DNA polymerase III subunits gamma and tau; Validated
345-666 1.64e-13

DNA polymerase III subunits gamma and tau; Validated


Pssm-ID: 236090 [Multi-domain]  Cd Length: 824  Bit Score: 73.87  E-value: 1.64e-13
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 33286446  345 PQPRSVEPQDAGPLERSQGDEAGGHGEDRPEPlspkeskkrklelsrREQPPTEPGPQSASEVEkialnleGCALSQGSL 424
Cdd:PRK07764 437 PAPAPPSPAGNAPAGGAPSPPPAAAPSAQPAP---------------APAAAPEPTAAPAPAPP-------AAPAPAAAP 494
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 33286446  425 RTGTQEVGGQDPGEAVQPcrQPLGARVADKVRKR-RKVDEGAGDSAAVASGGAQTLALAGSPAPSGH--PKAGHSENGVE 501
Cdd:PRK07764 495 AAPAAPAAPAGADDAATL--RERWPEILAAVPKRsRKTWAILLPEATVLGVRGDTLVLGFSTGGLARrfASPGNAEVLVT 572
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 33286446  502 --EDTEGRT--------GPKEGTPGSPSETPGPSPAGPAGDEPAESPSETPGPRPAGPAGDEPAESPSETPGPRPAGPAG 571
Cdd:PRK07764 573 alAEELGGDwqveavvgPAPGAAGGEGPPAPASSGPPEEAARPAAPAAPAAPAAPAPAGAAAAPAEASAAPAPGVAAPEH 652
                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 33286446  572 DEPAESPSETPGPSPAGPTRDEPAESPSETPGPRPAGPAGDEPAESPSETPGPR---PAGPAGDEPAESPSETPGPSPAG 648
Cdd:PRK07764 653 HPKHVAVPDASDGGDGWPAKAGGAAPAAPPPAPAPAAPAAPAGAAPAQPAPAPAatpPAGQADDPAAQPPQAAQGASAPS 732
                        330
                 ....*....|....*...
gi 33286446  649 PTRDEPAKAGEAAELQDA 666
Cdd:PRK07764 733 PAADDPVPLPPEPDDPPD 750
PHA03169 PHA03169
hypothetical protein; Provisional
478-666 3.43e-13

hypothetical protein; Provisional


Pssm-ID: 223003 [Multi-domain]  Cd Length: 413  Bit Score: 71.93  E-value: 3.43e-13
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 33286446  478 TLALAGSPAPSGHPKAGHSENGVEEDTEGRTGPKEGTPGSP--SETPGPSPAGPAGDEPAESPSETPGPRPAGPAGDEPA 555
Cdd:PHA03169  39 TAARAAKPAPPAPTTSGPQVRAVAEQGHRQTESDTETAEESrhGEKEERGQGGPSGSGSESVGSPTPSPSGSAEELASGL 118
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 33286446  556 EsPSETPGPRPAGPAGDEPAESPSETPGP-SPAGPTRDEPAESPSETPGPRPAGPAGDEPAESPSETPGPR-PAGPAGDE 633
Cdd:PHA03169 119 S-PENTSGSSPESPASHSPPPSPPSHPGPhEPAPPESHNPSPNQQPSSFLQPSHEDSPEEPEPPTSEPEPDsPGPPQSET 197
                        170       180       190
                 ....*....|....*....|....*....|...
gi 33286446  634 PAESPSETPGPSPAGPTRDEPAKAGEAAELQDA 666
Cdd:PHA03169 198 PTSSPPPQSPPDEPGEPQSPTPQQAPSPNTQQA 230
PRK07764 PRK07764
DNA polymerase III subunits gamma and tau; Validated
430-668 5.10e-13

DNA polymerase III subunits gamma and tau; Validated


Pssm-ID: 236090 [Multi-domain]  Cd Length: 824  Bit Score: 72.33  E-value: 5.10e-13
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 33286446  430 EVGGQDPGEAVQPCRQPLGARVADKVRKRRKVDEGAGDSAAVASGGAQTLALAGSPAPSGHPKAGHSENGVEEdtegrTG 509
Cdd:PRK07764 587 VVGPAPGAAGGEGPPAPASSGPPEEAARPAAPAAPAAPAAPAPAGAAAAPAEASAAPAPGVAAPEHHPKHVAV-----PD 661
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 33286446  510 PKEGTPGSPSETPGPSPAGPAgdepaespsetPGPRPAGPAGDEPAESPSETPGPRPAGPAGdepaesPSETPGPSPAGP 589
Cdd:PRK07764 662 ASDGGDGWPAKAGGAAPAAPP-----------PAPAPAAPAAPAGAAPAQPAPAPAATPPAG------QADDPAAQPPQA 724
                        170       180       190       200       210       220       230
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 33286446  590 TRDEPAESPSETPGPRPAGPAGDEPAESPSETPGPRPAGPAGDEPAESPSETPGPSPAGPTRDEPAKAGEAAELQDAEV 668
Cdd:PRK07764 725 AQGASAPSPAADDPVPLPPEPDDPPDPAGAPAQPPPPPAPAPAAAPAAAPPPSPPSEEEEMAEDDAPSMDDEDRRDAEE 803
PRK07764 PRK07764
DNA polymerase III subunits gamma and tau; Validated
513-652 8.41e-13

DNA polymerase III subunits gamma and tau; Validated


Pssm-ID: 236090 [Multi-domain]  Cd Length: 824  Bit Score: 71.94  E-value: 8.41e-13
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 33286446  513 GTPGSPSETPGPSPAGPAGDEPAESPSEtPGPRPAGPAGDEPAESPSETPGPRPAGPAGDEPAESPSETPGPSPAGPtrd 592
Cdd:PRK07764 385 LGVAGGAGAPAAAAPSAAAAAPAAAPAP-AAAAPAAAAAPAPAAAPQPAPAPAPAPAPPSPAGNAPAGGAPSPPPAA--- 460
                         90       100       110       120       130       140
                 ....*....|....*....|....*....|....*....|....*....|....*....|
gi 33286446  593 epaeSPSETPGPRPAGPAGDEPAESPSETPGPRPAGPAgdEPAESPSETPGPSPAGPTRD 652
Cdd:PRK07764 461 ----APSAQPAPAPAAAPEPTAAPAPAPPAAPAPAAAP--AAPAAPAAPAGADDAATLRE 514
PRK07003 PRK07003
DNA polymerase III subunit gamma/tau;
512-672 8.81e-13

DNA polymerase III subunit gamma/tau;


Pssm-ID: 235906 [Multi-domain]  Cd Length: 830  Bit Score: 71.80  E-value: 8.81e-13
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 33286446  512 EGTPGSPSETPGPSPAGPAGDEPAESPSETPGP-RPAGPAGDEPAESPSETPGPRPAGPAGDEPAESPSETPGPSPAGPT 590
Cdd:PRK07003 359 EPAVTGGGAPGGGVPARVAGAVPAPGARAAAAVgASAVPAVTAVTGAAGAALAPKAAAAAAATRAEAPPAAPAPPATADR 438
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 33286446  591 RDEPAESPSETPGPRPAGPAGDEPAESPSETPGPRP---AGPAGDEPAESPSEtPGPSPAGPTRDEPAKAGEAAELQDAE 667
Cdd:PRK07003 439 GDDAADGDAPVPAKANARASADSRCDERDAQPPADSgsaSAPASDAPPDAAFE-PAPRAAAPSAATPAAVPDARAPAAAS 517

                 ....*
gi 33286446  668 VESSA 672
Cdd:PRK07003 518 REDAP 522
PRK07003 PRK07003
DNA polymerase III subunit gamma/tau;
432-672 2.91e-12

DNA polymerase III subunit gamma/tau;


Pssm-ID: 235906 [Multi-domain]  Cd Length: 830  Bit Score: 69.88  E-value: 2.91e-12
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 33286446  432 GGQDPGEAVQPcrqplgaRVADKVRKRRKVDEGAGDSAAVASGGAQTLALAGSPAPS---------GHPKAGHSENGVEE 502
Cdd:PRK07003 364 GGGAPGGGVPA-------RVAGAVPAPGARAAAAVGASAVPAVTAVTGAAGAALAPKaaaaaaatrAEAPPAAPAPPATA 436
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 33286446  503 DTEGRTGPKEGTPGSPSETPGPSPAGPA--GDEPAESPSETpgprpAGPAGDEPAESPSEtPGPRPAGPAgdEPAESPSE 580
Cdd:PRK07003 437 DRGDDAADGDAPVPAKANARASADSRCDerDAQPPADSGSA-----SAPASDAPPDAAFE-PAPRAAAPS--AATPAAVP 508
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 33286446  581 TPGPSPAGPTRDEPAESPSETPGPRPAGPAGDEPA-------------------------ESPSETPGPRPAGPAGDEPA 635
Cdd:PRK07003 509 DARAPAAASREDAPAAAAPPAPEARPPTPAAAAPAaraggaaaaldvlrnagmrvssdrgARAAAAAKPAAAPAAAPKPA 588
                        250       260       270
                 ....*....|....*....|....*....|....*..
gi 33286446  636 ESPSETPGPSPAGPTRDEPAKAGEAAELQDAEVESSA 672
Cdd:PRK07003 589 APRVAVQVPTPRARAATGDAPPNGAARAEQAAESRGA 625
PHA03247 PHA03247
large tegument protein UL36; Provisional
297-651 3.44e-12

large tegument protein UL36; Provisional


Pssm-ID: 223021 [Multi-domain]  Cd Length: 3151  Bit Score: 70.35  E-value: 3.44e-12
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 33286446   297 PSSLPHPLEGSRKVEEEGSPGDPDHEASTQGRTCGPEHSKGGGRVD------EGPQPRSVEPQDAGPLERSQGDEAGGHG 370
Cdd:PHA03247 2629 PSPSPAANEPDPHPPPTVPPPERPRDDPAPGRVSRPRRARRLGRAAqassppQRPRRRAARPTVGSLTSLADPPPPPPTP 2708
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 33286446   371 EDRPEPLSPKESKKRKLELSRREQPPTEPGPQSASEVEKIALNLEGCALSQGSLRTG-TQEVGGQDPGEAVQPCRQPLGA 449
Cdd:PHA03247 2709 EPAPHALVSATPLPPGPAAARQASPALPAAPAPPAVPAGPATPGGPARPARPPTTAGpPAPAPPAAPAAGPPRRLTRPAV 2788
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 33286446   450 RVADKVRKRRKVDEGAGDSAAVASGGAQTLALAGSPA------PSGHPKAGHSENGVEEDTEGRTGP--------KEGTP 515
Cdd:PHA03247 2789 ASLSESRESLPSPWDPADPPAAVLAPAAALPPAASPAgplpppTSAQPTAPPPPPGPPPPSLPLGGSvapggdvrRRPPS 2868
                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 33286446   516 GSPSETPGPSPAGPAGDEPAESPSETPGPRPAGPAGDEPAESPSETPGPRPAGPAGDEPAESPSETPGPSPAGPTrdEPA 595
Cdd:PHA03247 2869 RSPAAKPAAPARPPVRRLARPAVSRSTESFALPPDQPERPPQPQAPPPPQPQPQPPPPPQPQPPPPPPPRPQPPL--APT 2946
                         330       340       350       360       370
                  ....*....|....*....|....*....|....*....|....*....|....*.
gi 33286446   596 ESPSETPGPRPAGPAGDEPAESPSETPGPRPAGPagdePAESPSETPGPSPAGPTR 651
Cdd:PHA03247 2947 TDPAGAGEPSGAVPQPWLGALVPGRVAVPRFRVP----QPAPSREAPASSTPPLTG 2998
PHA03307 PHA03307
transcriptional regulator ICP4; Provisional
297-662 5.49e-12

transcriptional regulator ICP4; Provisional


Pssm-ID: 223039 [Multi-domain]  Cd Length: 1352  Bit Score: 69.43  E-value: 5.49e-12
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 33286446   297 PSSLPHPLEGSRKVEEEGSPGDPDHEASTQGRTCGPEHSKGGGRVDEGPQPRSVEPQDAGPLERSQGDEAGGHGEDRPEP 376
Cdd:PHA03307   73 PGPGTEAPANESRSTPTWSLSTLAPASPAREGSPTPPGPSSPDPPPPTPPPASPPPSPAPDLSEMLRPVGSPGPPPAASP 152
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 33286446   377 LSPkeskkrklELSRREQPPTEPGPQSASEVEKIALNLEGCALSQGSLRTGTQEVGGQDPGEAV--------QPCRQPLG 448
Cdd:PHA03307  153 PAA--------GASPAAVASDAASSRQAALPLSSPEETARAPSSPPAEPPPSTPPAAASPRPPRrsspisasASSPAPAP 224
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 33286446   449 ARvADKVRKRRKVDEGAGDSAAVASGGAQTLALAGSPAPSGHPKAghsengveEDTEGRTGPKEGTPGSPSETPGPSPAG 528
Cdd:PHA03307  225 GR-SAADDAGASSSDSSSSESSGCGWGPENECPLPRPAPITLPTR--------IWEASGWNGPSSRPGPASSSSSPRERS 295
                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 33286446   529 PAGDEPAESPSETPGPRPAGPAGDEPAESPSETPGPRPAGPAGDEPAESPSETPGPSPAGPtrdepaeSPSETPGPRPAG 608
Cdd:PHA03307  296 PSPSPSSPGSGPAPSSPRASSSSSSSRESSSSSTSSSSESSRGAAVSPGPSPSRSPSPSRP-------PPPADPSSPRKR 368
                         330       340       350       360       370
                  ....*....|....*....|....*....|....*....|....*....|....*.
gi 33286446   609 PAGDEPAESPSETPG--PRPAGPAGDEPAESPSETPGPSPAGPTRDEPAKAGEAAE 662
Cdd:PHA03307  369 PRPSRAPSSPAASAGrpTRRRARAAVAGRARRRDATGRFPAGRPRPSPLDAGAASG 424
PRK07003 PRK07003
DNA polymerase III subunit gamma/tau;
481-661 6.26e-12

DNA polymerase III subunit gamma/tau;


Pssm-ID: 235906 [Multi-domain]  Cd Length: 830  Bit Score: 69.11  E-value: 6.26e-12
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 33286446  481 LAGSPAPSGhpkaGHSENGVEEDTEGRTGPKEG-TPGSPSETPGPSPAGPAGDEPAESPSetpgPRPAGPAGDEPAESPS 559
Cdd:PRK07003 356 LAFEPAVTG----GGAPGGGVPARVAGAVPAPGaRAAAAVGASAVPAVTAVTGAAGAALA----PKAAAAAAATRAEAPP 427
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 33286446  560 ETPGPRPAGPAGDEPAESPSETPGPSPAGPTRDEPAESPSETPGPRP---AGPAGDEPAESPSEtPGPRPAGPAgdEPAE 636
Cdd:PRK07003 428 AAPAPPATADRGDDAADGDAPVPAKANARASADSRCDERDAQPPADSgsaSAPASDAPPDAAFE-PAPRAAAPS--AATP 504
                        170       180
                 ....*....|....*....|....*
gi 33286446  637 SPSETPGPSPAGPTRDEPAKAGEAA 661
Cdd:PRK07003 505 AAVPDARAPAAASREDAPAAAAPPA 529
PRK07764 PRK07764
DNA polymerase III subunits gamma and tau; Validated
534-671 9.75e-12

DNA polymerase III subunits gamma and tau; Validated


Pssm-ID: 236090 [Multi-domain]  Cd Length: 824  Bit Score: 68.47  E-value: 9.75e-12
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 33286446  534 PAESPSETPGPRPAGPAGDEPAESPSEtPGPRPAGPAGDEPAESPSETPGPSPAGPTRDEPAESPSETPGPRPAGPAgde 613
Cdd:PRK07764 386 GVAGGAGAPAAAAPSAAAAAPAAAPAP-AAAAPAAAAAPAPAAAPQPAPAPAPAPAPPSPAGNAPAGGAPSPPPAAA--- 461
                         90       100       110       120       130
                 ....*....|....*....|....*....|....*....|....*....|....*...
gi 33286446  614 paesPSETPGPRPAGPAGDEPAESPSETPGPSPAGPTRDEPAKAGEAAELQDAEVESS 671
Cdd:PRK07764 462 ----PSAQPAPAPAAAPEPTAAPAPAPPAAPAPAAAPAAPAAPAAPAGADDAATLRER 515
PHA03169 PHA03169
hypothetical protein; Provisional
437-650 1.42e-11

hypothetical protein; Provisional


Pssm-ID: 223003 [Multi-domain]  Cd Length: 413  Bit Score: 66.92  E-value: 1.42e-11
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 33286446  437 GEAVQPCRQPLGARVADKVRKRRKVDEGAGDSAAVASGGAQTLALAGSPAPSGHPK-----------AGHSENGVEEDTE 505
Cdd:PHA03169  28 GTREQAGRRRGTAARAAKPAPPAPTTSGPQVRAVAEQGHRQTESDTETAEESRHGEkeergqggpsgSGSESVGSPTPSP 107
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 33286446  506 GRTGPKEGTPGSPSETPGPSPAGPAGDEPAESPSETPGP-RPAGPAGDEPAESPSETPGPRPAGPAGDEPAESPSETPGP 584
Cdd:PHA03169 108 SGSAEELASGLSPENTSGSSPESPASHSPPPSPPSHPGPhEPAPPESHNPSPNQQPSSFLQPSHEDSPEEPEPPTSEPEP 187
                        170       180       190       200       210       220
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 33286446  585 -SPAGPTRDEPAESPSETPGPRPAGPAGdepAESPSETPGPRPAGPAGDEPAESPSETPGPSPAGPT 650
Cdd:PHA03169 188 dSPGPPQSETPTSSPPPQSPPDEPGEPQ---SPTPQQAPSPNTQQAVEHEDEPTEPEREGPPFPGHR 251
PRK12323 PRK12323
DNA polymerase III subunit gamma/tau;
473-677 2.31e-11

DNA polymerase III subunit gamma/tau;


Pssm-ID: 237057 [Multi-domain]  Cd Length: 700  Bit Score: 66.82  E-value: 2.31e-11
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 33286446  473 SGGAQTLALAGSPAPSGHPKAGHSENGVeedTEGRTGPKEGTPGSPSETPGPSPAGPAGDEPAESPSETPGPRPAGPAGD 552
Cdd:PRK12323 368 SGGGAGPATAAAAPVAQPAPAAAAPAAA---APAPAAPPAAPAAAPAAAAAARAVAAAPARRSPAPEALAAARQASARGP 444
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 33286446  553 EPAESPSETPGPRPAgPAGDEPAESPSETPGPSPAGPTRDEPAESPSETPGPRPagPAGDEPAESPSETPGPRPAGPAGD 632
Cdd:PRK12323 445 GGAPAPAPAPAAAPA-AAARPAAAGPRPVAAAAAAAPARAAPAAAPAPADDDPP--PWEELPPEFASPAPAQPDAAPAGW 521
                        170       180       190       200
                 ....*....|....*....|....*....|....*....|....*.
gi 33286446  633 EPAESPSE-TPGPSPAGPTRDEPAKAGEAAElQDAEVESSAKSGKP 677
Cdd:PRK12323 522 VAESIPDPaTADPDDAFETLAPAPAAAPAPR-AAAATEPVVAPRPP 566
PRK07764 PRK07764
DNA polymerase III subunits gamma and tau; Validated
505-638 4.02e-11

DNA polymerase III subunits gamma and tau; Validated


Pssm-ID: 236090 [Multi-domain]  Cd Length: 824  Bit Score: 66.16  E-value: 4.02e-11
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 33286446  505 EGRTGPKEGTPGSPSETPGPSPAGPAGDEPAESPSETPGPRPAGPAGDEPAESPSETPGPrpaGPAGDEPAESPSETPGP 584
Cdd:PRK07764 382 ERRLGVAGGAGAPAAAAPSAAAAAPAAAPAPAAAAPAAAAAPAPAAAPQPAPAPAPAPAP---PSPAGNAPAGGAPSPPP 458
                         90       100       110       120       130
                 ....*....|....*....|....*....|....*....|....*....|....
gi 33286446  585 SPAGPTRDEPAESPSETPGPRPAGPAGDEPAESPSETPGPRPAGPAGDEPAESP 638
Cdd:PRK07764 459 AAAPSAQPAPAPAAAPEPTAAPAPAPPAAPAPAAAPAAPAAPAAPAGADDAATL 512
PRK12323 PRK12323
DNA polymerase III subunit gamma/tau;
423-663 1.45e-10

DNA polymerase III subunit gamma/tau;


Pssm-ID: 237057 [Multi-domain]  Cd Length: 700  Bit Score: 64.51  E-value: 1.45e-10
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 33286446  423 SLRTGTQEVGGQDPGEAVQPCRQPLGARVADKVRKRRKVDEGAGDSAAVASGGAQTLALAGSPAPSGHPKAghsengvee 502
Cdd:PRK12323 362 AFRPGQSGGGAGPATAAAAPVAQPAPAAAAPAAAAPAPAAPPAAPAAAPAAAAAARAVAAAPARRSPAPEA--------- 432
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 33286446  503 DTEGRTGPKEGTPGSPSetPGPSPAG---PAGDEPAESPSETPGPRPAGPAGDEPAESPSETPGPRPagPAGDEPAESPS 579
Cdd:PRK12323 433 LAAARQASARGPGGAPA--PAPAPAAapaAAARPAAAGPRPVAAAAAAAPARAAPAAAPAPADDDPP--PWEELPPEFAS 508
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 33286446  580 ETPGPSPAGPTRDEPAESPSetPGPRPAGPAGDEPAESPSETPGPRPAGPAgdepaeSPSETPGPSPAGPTRDEPAKAGE 659
Cdd:PRK12323 509 PAPAQPDAAPAGWVAESIPD--PATADPDDAFETLAPAPAAAPAPRAAAAT------EPVVAPRPPRASASGLPDMFDGD 580

                 ....
gi 33286446  660 AAEL 663
Cdd:PRK12323 581 WPAL 584
PHA03247 PHA03247
large tegument protein UL36; Provisional
465-657 2.71e-10

large tegument protein UL36; Provisional


Pssm-ID: 223021 [Multi-domain]  Cd Length: 3151  Bit Score: 64.19  E-value: 2.71e-10
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 33286446   465 AGDSAAVASGGAQTLALAGSPAPSGHPKAGHSENGVEEDTEGRTGPKEGTPGSPSETPGPSPAGP---AGDEPAESPSET 541
Cdd:PHA03247 2630 SPSPAANEPDPHPPPTVPPPERPRDDPAPGRVSRPRRARRLGRAAQASSPPQRPRRRAARPTVGSltsLADPPPPPPTPE 2709
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 33286446   542 PGPRPAGPAGDEP---------AESPSETPGPR-----PAGPAGDEPAESPSETPGPSPAGPTRDEPAESPSETPGP--- 604
Cdd:PHA03247 2710 PAPHALVSATPLPpgpaaarqaSPALPAAPAPPavpagPATPGGPARPARPPTTAGPPAPAPPAAPAAGPPRRLTRPava 2789
                         170       180       190       200       210
                  ....*....|....*....|....*....|....*....|....*....|....*...
gi 33286446   605 -----RPAGPAGDEPAESPSETPGPRPAGPAGDEPAespSETPGPSPAGPTRDEPAKA 657
Cdd:PHA03247 2790 slsesRESLPSPWDPADPPAAVLAPAAALPPAASPA---GPLPPPTSAQPTAPPPPPG 2844
PRK07764 PRK07764
DNA polymerase III subunits gamma and tau; Validated
503-630 4.02e-10

DNA polymerase III subunits gamma and tau; Validated


Pssm-ID: 236090 [Multi-domain]  Cd Length: 824  Bit Score: 63.08  E-value: 4.02e-10
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 33286446  503 DTEGRTGPKEGTPGSPSETPGPSPAGPAGDEPAESPSETPGPRPAGPAGDEPAESPSETPGPRPAGPAGDEPAESPSETP 582
Cdd:PRK07764 391 AGAPAAAAPSAAAAAPAAAPAPAAAAPAAAAAPAPAAAPQPAPAPAPAPAPPSPAGNAPAGGAPSPPPAAAPSAQPAPAP 470
                         90       100       110       120
                 ....*....|....*....|....*....|....*....|....*...
gi 33286446  583 GPSPAGPTRDEPAESPSETPGPRPAGPAGDEPAESPSETPGPRPAGPA 630
Cdd:PRK07764 471 AAAPEPTAAPAPAPPAAPAPAAAPAAPAAPAAPAGADDAATLRERWPE 518
PHA03307 PHA03307
transcriptional regulator ICP4; Provisional
461-675 5.04e-10

transcriptional regulator ICP4; Provisional


Pssm-ID: 223039 [Multi-domain]  Cd Length: 1352  Bit Score: 62.88  E-value: 5.04e-10
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 33286446   461 VDEGAGDSAAVASGGAQTLALAGSPAPSGHPKAGHSENGVEEDTEGRTGPKegTPGSPSETPGPSPAGPAGDEPAESPSE 540
Cdd:PHA03307   45 SDSAELAAVTVVAGAAACDRFEPPTGPPPGPGTEAPANESRSTPTWSLSTL--APASPAREGSPTPPGPSSPDPPPPTPP 122
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 33286446   541 tpgprPAGPAGDEPAESPSETPGPRPAGPAGDEPAESPSETPGPSPAGPTRDEPAESPSETPgPRPAGPAGDEPAESPSE 620
Cdd:PHA03307  123 -----PASPPPSPAPDLSEMLRPVGSPGPPPAASPPAAGASPAAVASDAASSRQAALPLSSP-EETARAPSSPPAEPPPS 196
                         170       180       190       200       210
                  ....*....|....*....|....*....|....*....|....*....|....*
gi 33286446   621 TPGPRPAGPAGDEPAESPSETPGPSPAGPtRDEPAKAGEAAELQDAEVESSAKSG 675
Cdd:PHA03307  197 TPPAAASPRPPRRSSPISASASSPAPAPG-RSAADDAGASSSDSSSSESSGCGWG 250
PHA03307 PHA03307
transcriptional regulator ICP4; Provisional
297-632 7.53e-10

transcriptional regulator ICP4; Provisional


Pssm-ID: 223039 [Multi-domain]  Cd Length: 1352  Bit Score: 62.50  E-value: 7.53e-10
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 33286446   297 PSSLPHPLEGSRKVEEEGSPGDPDHEASTQGRTCGPEHSKG-GGRVDEGPQPRSVEPQDAGPLERSQGDEAGGHGEDRPE 375
Cdd:PHA03307  128 PSPAPDLSEMLRPVGSPGPPPAASPPAAGASPAAVASDAASsRQAALPLSSPEETARAPSSPPAEPPPSTPPAAASPRPP 207
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 33286446   376 PLSPKESKKRKLELSRREQPPTEPGPQSASevekialnleGCALSQGSLRTGTQEVGGQDPGEAVQPCRQPLGARVADKV 455
Cdd:PHA03307  208 RRSSPISASASSPAPAPGRSAADDAGASSS----------DSSSSESSGCGWGPENECPLPRPAPITLPTRIWEASGWNG 277
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 33286446   456 RKRRKVDEGAGDSAAVASGGAQTLALAGSPAPSGHPKAGHSEnGVEEDTEGRTGPKEGTPGSPSETPGPSPAgPAGDEPA 535
Cdd:PHA03307  278 PSSRPGPASSSSSPRERSPSPSPSSPGSGPAPSSPRASSSSS-SSRESSSSSTSSSSESSRGAAVSPGPSPS-RSPSPSR 355
                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 33286446   536 ESPSETPGPRPAGPAGDEPAESPSETPG--PRPAGPAGDEPAESPSETPGPSPAGPTRDEPAESPSETPGPRPAGPAGD- 612
Cdd:PHA03307  356 PPPPADPSSPRKRPRPSRAPSSPAASAGrpTRRRARAAVAGRARRRDATGRFPAGRPRPSPLDAGAASGAFYARYPLLTp 435
                         330       340
                  ....*....|....*....|...
gi 33286446   613 --EP-AESPSETPGPRPAGPAGD 632
Cdd:PHA03307  436 sgEPwPGSPPPPPGRVRYGGLGD 458
PHA03307 PHA03307
transcriptional regulator ICP4; Provisional
393-677 1.39e-09

transcriptional regulator ICP4; Provisional


Pssm-ID: 223039 [Multi-domain]  Cd Length: 1352  Bit Score: 61.73  E-value: 1.39e-09
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 33286446   393 EQPPTEPGPQS-ASEVEKIALNLEGCALSQGSLRTGTQEVGGQDPGEAVQPCRQPlgarvadkvrkrrkvdEGAGDSAAV 471
Cdd:PHA03307   69 TGPPPGPGTEApANESRSTPTWSLSTLAPASPAREGSPTPPGPSSPDPPPPTPPP----------------ASPPPSPAP 132
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 33286446   472 ASGGAQTLALAGSPAPSGHPKAGHSENG-VEEDTEGRTGPKEGTPGSPSETPGPSPagPAGDEPAESPSetPGPRPAGPA 550
Cdd:PHA03307  133 DLSEMLRPVGSPGPPPAASPPAAGASPAaVASDAASSRQAALPLSSPEETARAPSS--PPAEPPPSTPP--AAASPRPPR 208
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 33286446   551 GDEPAESPSETPGPRPAGPAGDEPAESPSETPGPSPAGPTRDEPAESPSETPGPRPAGPAGDEPAESPSETPGPRPAGPA 630
Cdd:PHA03307  209 RSSPISASASSPAPAPGRSAADDAGASSSDSSSSESSGCGWGPENECPLPRPAPITLPTRIWEASGWNGPSSRPGPASSS 288
                         250       260       270       280
                  ....*....|....*....|....*....|....*....|....*..
gi 33286446   631 GDEPAESPSETPGPSPAGPTRDEPAKAGEAAELQDAEVESSAKSGKP 677
Cdd:PHA03307  289 SSPRERSPSPSPSSPGSGPAPSSPRASSSSSSSRESSSSSTSSSSES 335
PHA03307 PHA03307
transcriptional regulator ICP4; Provisional
475-677 2.04e-09

transcriptional regulator ICP4; Provisional


Pssm-ID: 223039 [Multi-domain]  Cd Length: 1352  Bit Score: 60.96  E-value: 2.04e-09
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 33286446   475 GAQTLALAGSPAPSGHPKAGHSENGVEEDTEGRTGPKEGTPGSPSETPGPSPAGPAGDEPAESPSETPGPRPAGPAGDEP 554
Cdd:PHA03307   17 GGEFFPRPPATPGDAADDLLSGSQGQLVSDSAELAAVTVVAGAAACDRFEPPTGPPPGPGTEAPANESRSTPTWSLSTLA 96
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 33286446   555 AESPSETPGPRPAGPAGDEPAESPSETPGPSPAGPTRDEPAESPSETPGPRPAG---PAGDEPAESPSETPGPRPAGPAG 631
Cdd:PHA03307   97 PASPAREGSPTPPGPSSPDPPPPTPPPASPPPSPAPDLSEMLRPVGSPGPPPAAsppAAGASPAAVASDAASSRQAALPL 176
                         170       180       190       200
                  ....*....|....*....|....*....|....*....|....*.
gi 33286446   632 DEPAESPSETPGPSPAGPTRDEPAKAGEAAELQDAEVESSAKSGKP 677
Cdd:PHA03307  177 SSPEETARAPSSPPAEPPPSTPPAAASPRPPRRSSPISASASSPAP 222
PRK08691 PRK08691
DNA polymerase III subunits gamma and tau; Validated
490-658 5.43e-09

DNA polymerase III subunits gamma and tau; Validated


Pssm-ID: 236333 [Multi-domain]  Cd Length: 709  Bit Score: 59.34  E-value: 5.43e-09
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 33286446  490 HPKAGHS--ENGVEEDTEGRTgPKEGTPGSPS--ETPGPSPAGPAGDEPAESPSE---TPGPRPAGPAGD---------E 553
Cdd:PRK08691 359 APLAAAScdANAVIENTELQS-PSAQTAEKETaaKKPQPRPEAETAQTPVQTASAaamPSEGKTAGPVSNqenndvppwE 437
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 33286446  554 PAESPSETPGPRPAGPAGDEPAESPSETPGPSPAGPTR---DEPAESPSETPGPRPAGPA-GDEPAESPS---ETPGPRP 626
Cdd:PRK08691 438 DAPDEAQTAAGTAQTSAKSIQTASEAETPPENQVSKNKaadNETDAPLSEVPSENPIQATpNDEAVETETfahEAPAEPF 517
                        170       180       190       200
                 ....*....|....*....|....*....|....*....|...
gi 33286446  627 AG---PAGDEPAESPSETPGP--------SPAGPTRDEPAKAG 658
Cdd:PRK08691 518 YGygfPDNDCPPEDGAEIPPPdwehaapaDTAGGGADEEAEAG 560
PRK14951 PRK14951
DNA polymerase III subunits gamma and tau; Provisional
526-667 5.76e-09

DNA polymerase III subunits gamma and tau; Provisional


Pssm-ID: 237865 [Multi-domain]  Cd Length: 618  Bit Score: 59.34  E-value: 5.76e-09
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 33286446  526 PAGpAGDEPAESPSETPGPRPAGPAGDEPAESPSETPGPRPAGPAGDEPAESPSETPGPSPAGPTRDEPAESPsETPGPR 605
Cdd:PRK14951 366 PAA-AAEAAAPAEKKTPARPEAAAPAAAPVAQAAAAPAPAAAPAAAASAPAAPPAAAPPAPVAAPAAAAPAAA-PAAAPA 443
                         90       100       110       120       130       140
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 33286446  606 PAGPAGDEPAESPSETPGPRP---AGPAGDEPAESPSETPGPSPAGPTRDEPAKAGEAAELQDAE 667
Cdd:PRK14951 444 AVALAPAPPAQAAPETVAIPVrvaPEPAVASAAPAPAAAPAAARLTPTEEGDVWHATVQQLAAAE 508
PRK07764 PRK07764
DNA polymerase III subunits gamma and tau; Validated
545-672 8.81e-09

DNA polymerase III subunits gamma and tau; Validated


Pssm-ID: 236090 [Multi-domain]  Cd Length: 824  Bit Score: 58.84  E-value: 8.81e-09
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 33286446  545 RPAGPAGDEPAESPSEtPGPRPAGPAGDEPAESPSETPGPSPAGPTRDEPAESPSETPGPrpaGPAGDEPAESPSETPGP 624
Cdd:PRK07764 383 RRLGVAGGAGAPAAAA-PSAAAAAPAAAPAPAAAAPAAAAAPAPAAAPQPAPAPAPAPAP---PSPAGNAPAGGAPSPPP 458
                         90       100       110       120
                 ....*....|....*....|....*....|....*....|....*...
gi 33286446  625 RPAGPAGDEPAESPSETPGPSPAGPTRDEPAKAGEAAELQDAEVESSA 672
Cdd:PRK07764 459 AAAPSAQPAPAPAAAPEPTAAPAPAPPAAPAPAAAPAAPAAPAAPAGA 506
PTZ00449 PTZ00449
104 kDa microneme/rhoptry antigen; Provisional
485-632 1.07e-08

104 kDa microneme/rhoptry antigen; Provisional


Pssm-ID: 185628 [Multi-domain]  Cd Length: 943  Bit Score: 58.55  E-value: 1.07e-08
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 33286446  485 PAPSGHPKAG----HSENGVEEDTEGRTGPKE-GTPGSPSETPGPSPAGPAGD-EPAESPSETpgPRPAGPAGDEPAESP 558
Cdd:PTZ00449 514 PEASGLPPKApgdkEGEEGEHEDSKESDEPKEgGKPGETKEGEVGKKPGPAKEhKPSKIPTLS--KKPEFPKDPKHPKDP 591
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 33286446  559 SEtpgprPAGPAGDEPAESPSETPGPS-------PAGPTRDEPAESPSETPGP-RPAGPAGDEPAESPSETPGPRPAGPA 630
Cdd:PTZ00449 592 EE-----PKKPKRPRSAQRPTRPKSPKlpelldiPKSPKRPESPKSPKRPPPPqRPSSPERPEGPKIIKSPKPPKSPKPP 666

                 ..
gi 33286446  631 GD 632
Cdd:PTZ00449 667 FD 668
PRK07994 PRK07994
DNA polymerase III subunits gamma and tau; Validated
510-675 1.11e-08

DNA polymerase III subunits gamma and tau; Validated


Pssm-ID: 236138 [Multi-domain]  Cd Length: 647  Bit Score: 58.34  E-value: 1.11e-08
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 33286446  510 PKEGTPGSPSETPGPSPAGPAgdepAESPSETPGPRPAGPAGDEPAESPSETPGPRPAGPAGDEPAESPSETPGPSPAGP 589
Cdd:PRK07994 371 PPQSAAPAASAQATAAPTAAV----APPQAPAVPPPPASAPQQAPAVPLPETTSQLLAARQQLQRAQGATKAKKSEPAAA 446
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 33286446  590 TRDEPAESPSETPGPRPAGPAGDEPAESPSETPGPRPAGPAGDEPAES--PSETPGPSPAGPTRDEPAKAGEAAELQD-- 665
Cdd:PRK07994 447 SRARPVNSALERLASVRPAPSALEKAPAKKEAYRWKATNPVEVKKEPVatPKALKKALEHEKTPELAAKLAAEAIERDpw 526
                        170
                 ....*....|.
gi 33286446  666 -AEVESSAKSG 675
Cdd:PRK07994 527 aALVSQLGLPG 537
PRK07764 PRK07764
DNA polymerase III subunits gamma and tau; Validated
469-677 1.80e-08

DNA polymerase III subunits gamma and tau; Validated


Pssm-ID: 236090 [Multi-domain]  Cd Length: 824  Bit Score: 57.69  E-value: 1.80e-08
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 33286446  469 AAVASGGAQTLALAGSPAPSGHPKAGHSENGVEEDTEGRTGPKEGTPGSPSETPGPSPAGPAGDEPAESPSETPGPRPAG 548
Cdd:PRK07764 413 AAAAPAAAAAPAPAAAPQPAPAPAPAPAPPSPAGNAPAGGAPSPPPAAAPSAQPAPAPAAAPEPTAAPAPAPPAAPAPAA 492
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 33286446  549 PAGDEPAESPSETPGPRP-------------------------------------------------------------- 566
Cdd:PRK07764 493 APAAPAAPAAPAGADDAAtlrerwpeilaavpkrsrktwaillpeatvlgvrgdtlvlgfstgglarrfaspgnaevlvt 572
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 33286446  567 -------------AGPAGDEPAESPSETPGPSPAGPTRDEPAESPSETPGPRPAGPAGDEPAES-PSETPGPRPAGPAGD 632
Cdd:PRK07764 573 alaeelggdwqveAVVGPAPGAAGGEGPPAPASSGPPEEAARPAAPAAPAAPAAPAPAGAAAAPaEASAAPAPGVAAPEH 652
                        250       260       270       280
                 ....*....|....*....|....*....|....*....|....*
gi 33286446  633 EPAESPSETPGPSPAGPTRDEPAKAGEAAELQDAEVESSAKSGKP 677
Cdd:PRK07764 653 HPKHVAVPDASDGGDGWPAKAGGAAPAAPPPAPAPAAPAAPAGAA 697
dnaA PRK14086
chromosomal replication initiator protein DnaA;
445-650 2.33e-08

chromosomal replication initiator protein DnaA;


Pssm-ID: 237605 [Multi-domain]  Cd Length: 617  Bit Score: 57.14  E-value: 2.33e-08
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 33286446  445 QPLGARVADKVRKRRKVDEGAGDSAAvASGGAQTLALAGSPAPSGHPKAGHSENgveedtegRTGPKEGTPGSPSETPGP 524
Cdd:PRK14086  72 ETLSRELGRPIRIAITVDPSAGEPAP-PPPHARRTSEPELPRPGRRPYEGYGGP--------RADDRPPGLPRQDQLPTA 142
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 33286446  525 SPAGPAgdepaESPSETPG--PRPAGPAG-----------DEPAESPSETPGP-RPAGPAGDEPAESPSETPGPSPAGPT 590
Cdd:PRK14086 143 RPAYPA-----YQQRPEPGawPRAADDYGwqqqrlgfpprAPYASPASYAPEQeRDREPYDAGRPEYDQRRRDYDHPRPD 217
                        170       180       190       200       210       220
                 ....*....|....*....|....*....|....*....|....*....|....*....|...
gi 33286446  591 RDEPAESPSETPGPRPAG---PAGDEPAESPSETPGPRPAGPAGDEPAESPSETPGpsPAGPT 650
Cdd:PRK14086 218 WDRPRRDRTDRPEPPPGAghvHRGGPGPPERDDAPVVPIRPSAPGPLAAQPAPAPG--PGEPT 278
PRK07003 PRK07003
DNA polymerase III subunit gamma/tau;
547-677 2.49e-08

DNA polymerase III subunit gamma/tau;


Pssm-ID: 235906 [Multi-domain]  Cd Length: 830  Bit Score: 57.17  E-value: 2.49e-08
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 33286446  547 AGPAGDEPAESPSETPGPRPAGPAGDEPAESPSETPgpspagptrdePAESPSETPGPRPAGPAGDEPAESPSETPGPRP 626
Cdd:PRK07003 366 GAPGGGVPARVAGAVPAPGARAAAAVGASAVPAVTA-----------VTGAAGAALAPKAAAAAAATRAEAPPAAPAPPA 434
                         90       100       110       120       130
                 ....*....|....*....|....*....|....*....|....*....|.
gi 33286446  627 AGPAGDEPAESPSETPGPSPAGPTRDEPAKAGEAAELQDAEVESSAKSGKP 677
Cdd:PRK07003 435 TADRGDDAADGDAPVPAKANARASADSRCDERDAQPPADSGSASAPASDAP 485
PHA03247 PHA03247
large tegument protein UL36; Provisional
483-662 2.93e-08

large tegument protein UL36; Provisional


Pssm-ID: 223021 [Multi-domain]  Cd Length: 3151  Bit Score: 57.64  E-value: 2.93e-08
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 33286446   483 GSPAPSGHPKAGHSENGVEEDTEGRTGPKEGTPGSPSETPGPSPAG-------PAGDEPAESPSETPGP-------RPAG 548
Cdd:PHA03247 2590 DAPPQSARPRAPVDDRGDPRGPAPPSPLPPDTHAPDPPPPSPSPAAnepdphpPPTVPPPERPRDDPAPgrvsrprRARR 2669
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 33286446   549 PAGDEPAESPSETPGPRPAGPA-------GDEPAESPSETPGP---SPAGPTRDEPAESPSETPGPrPAGPAGDEPAESP 618
Cdd:PHA03247 2670 LGRAAQASSPPQRPRRRAARPTvgsltslADPPPPPPTPEPAPhalVSATPLPPGPAAARQASPAL-PAAPAPPAVPAGP 2748
                         170       180       190       200
                  ....*....|....*....|....*....|....*....|....*...
gi 33286446   619 ----SETPGPRPAGPAGDEPAESPSETPGPSPAGPTRDEPAKAGEAAE 662
Cdd:PHA03247 2749 atpgGPARPARPPTTAGPPAPAPPAAPAAGPPRRLTRPAVASLSESRE 2796
PHA03247 PHA03247
large tegument protein UL36; Provisional
518-677 3.11e-08

large tegument protein UL36; Provisional


Pssm-ID: 223021 [Multi-domain]  Cd Length: 3151  Bit Score: 57.26  E-value: 3.11e-08
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 33286446   518 PSETPGPSPAGPAGDePAESPSETPGPRPAgPAGDEPAESPSETPG----PR-----------PAGPAGDEPAESPsetP 582
Cdd:PHA03247 2483 PAEARFPFAAGAAPD-PGGGGPPDPDAPPA-PSRLAPAILPDEPVGepvhPRmltwirgleelASDDAGDPPPPLP---P 2557
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 33286446   583 GPSPAGPTRdepaESPSETPGPRPAGPAGDEPAESPSETPGPR----PAGPAGDEPAESPSETPGPSPAGPTRDEPAKAG 658
Cdd:PHA03247 2558 AAPPAAPDR----SVPPPRPAPRPSEPAVTSRARRPDAPPQSArpraPVDDRGDPRGPAPPSPLPPDTHAPDPPPPSPSP 2633
                         170
                  ....*....|....*....
gi 33286446   659 EAAELQDAEVESSAKSGKP 677
Cdd:PHA03247 2634 AANEPDPHPPPTVPPPERP 2652
PHA03247 PHA03247
large tegument protein UL36; Provisional
483-677 4.12e-08

large tegument protein UL36; Provisional


Pssm-ID: 223021 [Multi-domain]  Cd Length: 3151  Bit Score: 56.87  E-value: 4.12e-08
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 33286446   483 GSPAPSGHPKAGHSENGVEEDTEGRTGPKEGTPGSPSETPGPSPAGPAGDEPAESP--------SETPGPRPAGPAGDEP 554
Cdd:PHA03247  274 GATGPPPPPEAAAPNGAAAPPDGVWGAALAGAPLALPAPPDPPPPAPAGDAEEEDDedgamevvSPLPRPRQHYPLGFPK 353
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 33286446   555 AESPSETP---------GPRPAGPAGDEPAESPSETPGPSP--AGPTRDEPAESPSETPGPRPAGPAGDEPAESPSETPG 623
Cdd:PHA03247  354 RRRPTWTPpssledlsaGRHHPKRASLPTRKRRSARHAATPfaRGPGGDDQTRPAAPVPASVPTPAPTPVPASAPPPPAT 433
                         170       180       190       200       210
                  ....*....|....*....|....*....|....*....|....*....|....
gi 33286446   624 PRPAGPAGDEpaESPSETPGPSPAGPTRDEPAKAGEAAELQDAEVESSAKSGKP 677
Cdd:PHA03247  434 PLPSAEPGSD--DGPAPPPERQPPAPATEPAPDDPDDATRKALDALRERRPPEP 485
PHA03378 PHA03378
EBNA-3B; Provisional
524-677 4.66e-08

EBNA-3B; Provisional


Pssm-ID: 223065 [Multi-domain]  Cd Length: 991  Bit Score: 56.61  E-value: 4.66e-08
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 33286446  524 PSPAGPAGDEPAESPSETPGPRPAGPAgdePAESPSETPGPRPAGPAGDEPAESPSETPGPSPAGPTRDEPAESPSETPG 603
Cdd:PHA03378 676 PSPTGANTMLPIQWAPGTMQPPPRAPT---PMRPPAAPPGRAQRPAAATGRARPPAAAPGRARPPAAAPGRARPPAAAPG 752
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 33286446  604 PRPAGPAGDEPAESPSETPG---PRPAGPAGDEPAESPSETPGPSP---AGPT------RDEPAKAGEAAELQDAEVESS 671
Cdd:PHA03378 753 RARPPAAAPGRARPPAAAPGaptPQPPPQAPPAPQQRPRGAPTPQPppqAGPTsmqlmpRAAPGQQGPTKQILRQLLTGG 832

                 ....*.
gi 33286446  672 AKSGKP 677
Cdd:PHA03378 833 VKRGRP 838
PRK14951 PRK14951
DNA polymerase III subunits gamma and tau; Provisional
512-649 6.60e-08

DNA polymerase III subunits gamma and tau; Provisional


Pssm-ID: 237865 [Multi-domain]  Cd Length: 618  Bit Score: 55.88  E-value: 6.60e-08
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 33286446  512 EGTPGSPSETPGPSPAGPAGDEPAESPSETPGPRPAGPAGDEPAESPsetPGPRPAGPAGDEPAESPSETPgpsPAGPTR 591
Cdd:PRK14951 371 EAAAPAEKKTPARPEAAAPAAAPVAQAAAAPAPAAAPAAAASAPAAP---PAAAPPAPVAAPAAAAPAAAP---AAAPAA 444
                         90       100       110       120       130
                 ....*....|....*....|....*....|....*....|....*....|....*...
gi 33286446  592 DEPAESPSETPGPRPAgpagdepAESPSETPGPRPAGPAGDEPAESPSETPGPSPAGP 649
Cdd:PRK14951 445 VALAPAPPAQAAPETV-------AIPVRVAPEPAVASAAPAPAAAPAAARLTPTEEGD 495
PRK13108 PRK13108
prolipoprotein diacylglyceryl transferase; Reviewed
479-649 7.52e-08

prolipoprotein diacylglyceryl transferase; Reviewed


Pssm-ID: 237284 [Multi-domain]  Cd Length: 460  Bit Score: 55.37  E-value: 7.52e-08
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 33286446  479 LALAGSPAPSGHPKAGHSENGVEEdTEGRTGPKEGTPGSPSETPGPSPAGPA-GDEPAESPSETPGPRPAGPAGDEPAES 557
Cdd:PRK13108 274 LAPKGREAPGALRGSEYVVDEALE-REPAELAAAAVASAASAVGPVGPGEPNqPDDVAEAVKAEVAEVTDEVAAESVVQV 352
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 33286446  558 PSETPGPRPAGPAGDEPA---ESPSETPGPSPAGPTRDEPAES--PSETPGPRPAGPAGDEPAESPSETPGPRPagpagD 632
Cdd:PRK13108 353 ADRDGESTPAVEETSEADierEQPGDLAGQAPAAHQVDAEAASaaPEEPAALASEAHDETEPEVPEKAAPIPDP-----A 427
                        170
                 ....*....|....*..
gi 33286446  633 EPAESPSETPGPSPAGP 649
Cdd:PRK13108 428 KPDELAVAGPGDDPAEP 444
PHA03247 PHA03247
large tegument protein UL36; Provisional
523-665 7.99e-08

large tegument protein UL36; Provisional


Pssm-ID: 223021 [Multi-domain]  Cd Length: 3151  Bit Score: 56.10  E-value: 7.99e-08
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 33286446   523 GPSPAGPAGDEPAES----PSETPGPRPAGPAGDEPAESPSETPGPR----PAGPAGDEPAESPsetPGPSPAGPTRDEP 594
Cdd:PHA03247 2550 DPPPPLPPAAPPAAPdrsvPPPRPAPRPSEPAVTSRARRPDAPPQSArpraPVDDRGDPRGPAP---PSPLPPDTHAPDP 2626
                          90       100       110       120       130       140       150
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 33286446   595 aesPSETPGPRPAGPAGDEPAESPS-ETPGPRPAGPAGDEP--AESPSETPGPS--PAGPTRDE-PAKAGEAAELQD 665
Cdd:PHA03247 2627 ---PPPSPSPAANEPDPHPPPTVPPpERPRDDPAPGRVSRPrrARRLGRAAQASspPQRPRRRAaRPTVGSLTSLAD 2700
PRK13108 PRK13108
prolipoprotein diacylglyceryl transferase; Reviewed
446-611 8.35e-08

prolipoprotein diacylglyceryl transferase; Reviewed


Pssm-ID: 237284 [Multi-domain]  Cd Length: 460  Bit Score: 55.37  E-value: 8.35e-08
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 33286446  446 PLGARVADKVRKRRKVDEGAGDSAAVASGGAQTLALAGSPAPSGHPKAGHSENGVEEDTE-----GRTGPKEGTPGSPSE 520
Cdd:PRK13108 276 PKGREAPGALRGSEYVVDEALEREPAELAAAAVASAASAVGPVGPGEPNQPDDVAEAVKAevaevTDEVAAESVVQVADR 355
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 33286446  521 TPGPSPAGPAGDEPA---ESPSETPGPRPAGPAGDEPAES--PSETPGPRPAGPAGDEPAESPSETPGPSPagptrDEPA 595
Cdd:PRK13108 356 DGESTPAVEETSEADierEQPGDLAGQAPAAHQVDAEAASaaPEEPAALASEAHDETEPEVPEKAAPIPDP-----AKPD 430
                        170
                 ....*....|....*.
gi 33286446  596 ESPSETPGPRPAGPAG 611
Cdd:PRK13108 431 ELAVAGPGDDPAEPDG 446
dnaA PRK14086
chromosomal replication initiator protein DnaA;
510-674 9.72e-08

chromosomal replication initiator protein DnaA;


Pssm-ID: 237605 [Multi-domain]  Cd Length: 617  Bit Score: 55.22  E-value: 9.72e-08
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 33286446  510 PKEGTPGSPSETPgPSPAGPAGDEPAESPSETPGPRPAGPAGDEPAESPsETPGPRPAGPAGDEPAESPSETPGPSPAG- 588
Cdd:PRK14086  90 PSAGEPAPPPPHA-RRTSEPELPRPGRRPYEGYGGPRADDRPPGLPRQD-QLPTARPAYPAYQQRPEPGAWPRAADDYGw 167
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 33286446  589 -------PTRDEPAESPSETPGP-RPAGPAGDEPAESPSETPGPRPAGPAGDEPAESPSETPGPSPAGPTRdePAKAGEA 660
Cdd:PRK14086 168 qqqrlgfPPRAPYASPASYAPEQeRDREPYDAGRPEYDQRRRDYDHPRPDWDRPRRDRTDRPEPPPGAGHV--HRGGPGP 245
                        170
                 ....*....|....
gi 33286446  661 AELQDAEVESSAKS 674
Cdd:PRK14086 246 PERDDAPVVPIRPS 259
PTZ00449 PTZ00449
104 kDa microneme/rhoptry antigen; Provisional
501-674 1.10e-07

104 kDa microneme/rhoptry antigen; Provisional


Pssm-ID: 185628 [Multi-domain]  Cd Length: 943  Bit Score: 55.47  E-value: 1.10e-07
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 33286446  501 EEDTEGRTGPKEGtpgspSETPGPSPAGPaGDEPAESPSETPGPRPAGPA-GDEPAESPSETPGPRPaGPAGD-EPAESP 578
Cdd:PTZ00449 501 EEDSDKHDEPPEG-----PEASGLPPKAP-GDKEGEEGEHEDSKESDEPKeGGKPGETKEGEVGKKP-GPAKEhKPSKIP 573
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 33286446  579 SETPGP-------------SPAGPTRDEPAESPSETPGPR-------PAGPAGDEPAESPSETPGP-RPAGPAGDEPAES 637
Cdd:PTZ00449 574 TLSKKPefpkdpkhpkdpeEPKKPKRPRSAQRPTRPKSPKlpelldiPKSPKRPESPKSPKRPPPPqRPSSPERPEGPKI 653
                        170       180       190
                 ....*....|....*....|....*....|....*..
gi 33286446  638 PSETPGPSPAGPTRDEPAKageaAELQDAEVESSAKS 674
Cdd:PTZ00449 654 IKSPKPPKSPKPPFDPKFK----EKFYDDYLDAAAKS 686
PRK08691 PRK08691
DNA polymerase III subunits gamma and tau; Validated
484-660 1.47e-07

DNA polymerase III subunits gamma and tau; Validated


Pssm-ID: 236333 [Multi-domain]  Cd Length: 709  Bit Score: 54.71  E-value: 1.47e-07
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 33286446  484 SPAPSGHPKAGHSENGVEEDTEGRTGPKEGTPgSPSETPGPSPAGPAGDEPAESPSETPGPRPAG---PAGDEPAESPSE 560
Cdd:PRK08691 409 TASAAAMPSEGKTAGPVSNQENNDVPPWEDAP-DEAQTAAGTAQTSAKSIQTASEAETPPENQVSknkAADNETDAPLSE 487
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 33286446  561 TPGPRPAGPA-GDEPAESPS---ETPGPSPAG---PTRDEPAESPSETPGP--RPAGPAGDEPAESPSETpgpRPAGPAG 631
Cdd:PRK08691 488 VPSENPIQATpNDEAVETETfahEAPAEPFYGygfPDNDCPPEDGAEIPPPdwEHAAPADTAGGGADEEA---EAGGIGG 564
                        170       180       190
                 ....*....|....*....|....*....|
gi 33286446  632 DE-PAESPSETPGPSPAGPTRDEPAKAGEA 660
Cdd:PRK08691 565 NNtPSAPPPEFSTENWAAIVRHFARKLGAA 594
PHA03307 PHA03307
transcriptional regulator ICP4; Provisional
464-647 3.03e-07

transcriptional regulator ICP4; Provisional


Pssm-ID: 223039 [Multi-domain]  Cd Length: 1352  Bit Score: 54.02  E-value: 3.03e-07
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 33286446   464 GAGDSAAVASGGAQTLALAGSPAPSGHPKAGHSENGVEEDTEGRTGPKEGTPGSPSETPGPSPAGPAGDEPAESPSETPG 543
Cdd:PHA03307  763 LVPAKLAEALALLEPAEPQRGAGSSPPVRAEAAFRRPGRLRRSGPAADAASRTASKRKSRSHTPDGGSESSGPARPPGAA 842
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 33286446   544 PRPAGPAGDEPAESPSETPGPRPAGPAGDEPAESPSETPGPSPAGPTRDEPAESPSETPGPRPAGPAGDEPAESPSETPG 623
Cdd:PHA03307  843 ARPPPARSSESSKSKPAAAGGRARGKNGRRRPRPPEPRARPGAAAPPKAAAAAPPAGAPAPRPRPAPRVKLGPMPPGGPD 922
                         170       180
                  ....*....|....*....|....*..
gi 33286446   624 PRPAG---PAGdepaesPSETPGPSPA 647
Cdd:PHA03307  923 PRGGFrrvPPG------DLHTPAPSAA 943
PRK07764 PRK07764
DNA polymerase III subunits gamma and tau; Validated
538-672 3.69e-07

DNA polymerase III subunits gamma and tau; Validated


Pssm-ID: 236090 [Multi-domain]  Cd Length: 824  Bit Score: 53.45  E-value: 3.69e-07
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 33286446  538 PSETPGPRpAGPAGDEPAESPSETPGPRPAGPAGDEPAESPSETPGPSPAGPTR---DEPAESPSETPGPRPAgPAGDEP 614
Cdd:PRK07764 365 PSASDDER-GLLARLERLERRLGVAGGAGAPAAAAPSAAAAAPAAAPAPAAAAPaaaAAPAPAAAPQPAPAPA-PAPAPP 442
                         90       100       110       120       130
                 ....*....|....*....|....*....|....*....|....*....|....*...
gi 33286446  615 AESPSETPGPRPAGPAGDEPAESPSETPGPSPAGPTRDEPAKAGEAAELQDAEVESSA 672
Cdd:PRK07764 443 SPAGNAPAGGAPSPPPAAAPSAQPAPAPAAAPEPTAAPAPAPPAAPAPAAAPAAPAAP 500
PHA03378 PHA03378
EBNA-3B; Provisional
300-677 4.52e-07

EBNA-3B; Provisional


Pssm-ID: 223065 [Multi-domain]  Cd Length: 991  Bit Score: 53.53  E-value: 4.52e-07
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 33286446  300 LPHPLEGSRKVEEEGSPGDPDHEASTQGRTCGPEHSKGGGRVDEGPQPRSVEPQDAGPLERSQGDEAGGHGEDRPEPLSP 379
Cdd:PHA03378 564 LPAPGLGPLQIQPLTSPTTSQLASSAPSYAQTPWPVPHPSQTPEPPTTQSHIPETSAPRQWPMPLRPIPMRPLRMQPITF 643
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 33286446  380 KESKKRklelSRREQPPTEPGPQSASEVEKIALNLE-GCALSQGSLRTGTQEVGGQDPGEAVQPCRQPLGARVAdkvRKR 458
Cdd:PHA03378 644 NVLVFP----TPHQPPQVEITPYKPTWTQIGHIPYQpSPTGANTMLPIQWAPGTMQPPPRAPTPMRPPAAPPGR---AQR 716
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 33286446  459 RKVDEGAGDSAAVASGGAQTLALAGSPAPSghPKAGHSENGVEEDTEGRTGPKEGTPGSPSETPGPSPAGPAGDEPAESP 538
Cdd:PHA03378 717 PAAATGRARPPAAAPGRARPPAAAPGRARP--PAAAPGRARPPAAAPGRARPPAAAPGAPTPQPPPQAPPAPQQRPRGAP 794
                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 33286446  539 SETPGPR----------PAGPAGDEPAESPSE---TPGPRPAGPAGDEPAESPSETPG---PSPAGPTRDEPAESPSETP 602
Cdd:PHA03378 795 TPQPPPQagptsmqlmpRAAPGQQGPTKQILRqllTGGVKRGRPSLKKPAALERQAAAgptPSPGSGTSDKIVQAPVFYP 874
                        330       340       350       360       370       380       390       400
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 33286446  603 gprpagpagdePAESPSETPG----PRPAGP--AGDEPAESPSETPGPSPAGPTRDEPAKAGEaaelQDAEVESSAKSGK 676
Cdd:PHA03378 875 -----------PVLQPIQVMRqlgsVRAAAAstVTQAPTEYTGERRGVGPMHPTDIPPSKRAK----TDAYVESQPPHGG 939

                 .
gi 33286446  677 P 677
Cdd:PHA03378 940 Q 940
PHA03379 PHA03379
EBNA-3A; Provisional
492-657 4.80e-07

EBNA-3A; Provisional


Pssm-ID: 223066 [Multi-domain]  Cd Length: 935  Bit Score: 53.14  E-value: 4.80e-07
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 33286446  492 KAGHSENGVEEDTEGRTGPKEGTPGSPSETPGPSPAGPAGDEPAESPSETPGPRPAGPAGDEPAEspsETPGPRPAGPAG 571
Cdd:PHA03379 393 RAGKLTERAREALEKASEPTYGTPRPPVEKPRPEVPQSLETATSHGSAQVPEPPPVHDLEPGPLH---DQHSMAPCPVAQ 469
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 33286446  572 DEPAESPSETPGPSPAGPTRDepaESPSETPGPRPAGPAGDEPAESPSETPGPRPAGPAGDEPAESPSETPGPSPAGPTR 651
Cdd:PHA03379 470 LPPGPLQDLEPGDQLPGVVQD---GRPACAPVPAPAGPIVRPWEASLSQVPGVAFAPVMPQPMPVEPVPVPTVALERPVC 546

                 ....*.
gi 33286446  652 DEPAKA 657
Cdd:PHA03379 547 PAPPLI 552
PRK07764 PRK07764
DNA polymerase III subunits gamma and tau; Validated
464-677 4.90e-07

DNA polymerase III subunits gamma and tau; Validated


Pssm-ID: 236090 [Multi-domain]  Cd Length: 824  Bit Score: 53.07  E-value: 4.90e-07
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 33286446  464 GAGDSAAVASGGAQTLALAGSPAPSGHPKAGHSENgveedTEGRTGPKEGTPGSPSETPGPSPAGPAGDEPAESPSETPG 543
Cdd:PRK07764 403 AAAPAAAPAPAAAAPAAAAAPAPAAAPQPAPAPAP-----APAPPSPAGNAPAGGAPSPPPAAAPSAQPAPAPAAAPEPT 477
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 33286446  544 PRPAGPAGDEPAESPSETPGPRPAGPAGDEPAESPSE--------------------TPGPSPAGPTRDE---------- 593
Cdd:PRK07764 478 AAPAPAPPAAPAPAAAPAAPAAPAAPAGADDAATLRErwpeilaavpkrsrktwailLPEATVLGVRGDTlvlgfstggl 557
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 33286446  594 -------------------------------------PAESPSETPGPRPAGPAGDEPAESPSETPGPRPAGPAGDEPAE 636
Cdd:PRK07764 558 arrfaspgnaevlvtalaeelggdwqveavvgpapgaAGGEGPPAPASSGPPEEAARPAAPAAPAAPAAPAPAGAAAAPA 637
                        250       260       270       280
                 ....*....|....*....|....*....|....*....|.
gi 33286446  637 SPSETPGPSPAGPTRDEPAKAGEAAELQDAEVESSAKSGKP 677
Cdd:PRK07764 638 EASAAPAPGVAAPEHHPKHVAVPDASDGGDGWPAKAGGAAP 678
gly_rich_SclB NF038329
LPXTG-anchored collagen-like adhesin Scl2/SclB; SclB (or Scl2 - streptococcal collagen-like ...
456-658 5.12e-07

LPXTG-anchored collagen-like adhesin Scl2/SclB; SclB (or Scl2 - streptococcal collagen-like protein 2) is an LPXTG-anchored surface-anchored adhesin with a variable-length region of triple helix-forming collagen-like Gly-Xaa-Xaa repeats.


Pssm-ID: 468478 [Multi-domain]  Cd Length: 440  Bit Score: 52.60  E-value: 5.12e-07
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 33286446  456 RKRRKVDEGAGDSAAVASGGAQTLALAGSPAPSGHPKAGHSENGvEEDTEGRTGPK--EGTPGSPSETPGPSPAGPAGDE 533
Cdd:NF038329 101 SYLEELDEGLQQLKGDGEKGEPGPAGPAGPAGEQGPRGDRGETG-PAGPAGPPGPQgeRGEKGPAGPQGEAGPQGPAGKD 179
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 33286446  534 PAESPSETPGprPAGPAGDEPAESPSETPGPR-PAGPAGDEPAESPSETPGPSPAGPTRDEPAESPSETPGPR-PAGPAG 611
Cdd:NF038329 180 GEAGAKGPAG--EKGPQGPRGETGPAGEQGPAgPAGPDGEAGPAGEDGPAGPAGDGQQGPDGDPGPTGEDGPQgPDGPAG 257
                        170       180       190       200
                 ....*....|....*....|....*....|....*....|....*..
gi 33286446  612 DEPAESPSETPGprPAGPAGDEPAESPSETPGPSPAGPTRDEPAKAG 658
Cdd:NF038329 258 KDGPRGDRGEAG--PDGPDGKDGERGPVGPAGKDGQNGKDGLPGKDG 302
PRK07994 PRK07994
DNA polymerase III subunits gamma and tau; Validated
534-673 7.83e-07

DNA polymerase III subunits gamma and tau; Validated


Pssm-ID: 236138 [Multi-domain]  Cd Length: 647  Bit Score: 52.18  E-value: 7.83e-07
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 33286446  534 PAESPSETPGPRPAGPAGdePAESPSETPGPRPAGPAGDEPAESPSETPGPSPAGPTRDEPAESPSETPGPRPAGPAGDE 613
Cdd:PRK07994 361 PAAPLPEPEVPPQSAAPA--ASAQATAAPTAAVAPPQAPAVPPPPASAPQQAPAVPLPETTSQLLAARQQLQRAQGATKA 438
                         90       100       110       120       130       140
                 ....*....|....*....|....*....|....*....|....*....|....*....|
gi 33286446  614 PAESPSETPGPRPAgPAGDEPAESPSETPGPSPAGPTRDEPAkAGEAAELQDAEVESSAK 673
Cdd:PRK07994 439 KKSEPAAASRARPV-NSALERLASVRPAPSALEKAPAKKEAY-RWKATNPVEVKKEPVAT 496
SepH NF040712
septation protein SepH; Septation protein H (SepH) was firstly characterized in Streptomyces ...
512-661 9.36e-07

septation protein SepH; Septation protein H (SepH) was firstly characterized in Streptomyces venezuelae, and homologs were identified in Mycobacterium smegmatis. SepH contains a N-terminal DUF3071 domain and a conserved C-terminal region. It binds directly to cell division protein FtsZ to stimulate the assembly of FtsZ protofilaments.


Pssm-ID: 468676 [Multi-domain]  Cd Length: 346  Bit Score: 51.31  E-value: 9.36e-07
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 33286446  512 EGTPGSP--SETPGPSPAGPAGDEPAESPSETPGPRPAgpagdePAESPSETPGPRPAGPAGDEPAESPSETPGPSPAGP 589
Cdd:NF040712 189 DPDFGRPlrPLATVPRLAREPADARPEEVEPAPAAEGA------PATDSDPAEAGTPDDLASARRRRAGVEQPEDEPVGP 262
                         90       100       110       120       130       140       150
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 33286446  590 TRDEPAESPSETPGPRPagPAGDEPAESPSETPGPRPAGPAGDEPAESPSETPGPSPAGPTRDEPAKAGEAA 661
Cdd:NF040712 263 GAAPAAEPDEATRDAGE--PPAPGAAETPEAAEPPAPAPAAPAAPAAPEAEEPARPEPPPAPKPKRRRRRAS 332
Herpes_BLLF1 pfam05109
Herpes virus major outer envelope glycoprotein (BLLF1); This family consists of the BLLF1 ...
503-650 1.03e-06

Herpes virus major outer envelope glycoprotein (BLLF1); This family consists of the BLLF1 viral late glycoprotein, also termed gp350/220. It is the most abundantly expressed glycoprotein in the viral envelope of the Herpesviruses and is the major antigen responsible for stimulating the production of neutralising antibodies in vivo.


Pssm-ID: 282904 [Multi-domain]  Cd Length: 886  Bit Score: 52.23  E-value: 1.03e-06
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 33286446   503 DTEGRTGPKEgTPGSPSETPGPSP-AGPAGDEPAESPSETPGPRPAGPAGDEPAESPSetPGPRPAGPAGDEP-AESPSE 580
Cdd:pfam05109 435 NTTGFAAPNT-TTGLPSSTHVPTNlTAPASTGPTVSTADVTSPTPAGTTSGASPVTPS--PSPRDNGTESKAPdMTSPTS 511
                          90       100       110       120       130       140       150
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 33286446   581 ---TPGPSPAGPTrdePAESpseTPGPRPAGPA-GDEPAESPSETPGPRPAGPAgdePAESpseTPGPSPAGPT 650
Cdd:pfam05109 512 avtTPTPNATSPT---PAVT---TPTPNATSPTlGKTSPTSAVTTPTPNATSPT---PAVT---TPTPNATIPT 573
dnaA PRK14086
chromosomal replication initiator protein DnaA;
502-662 1.06e-06

chromosomal replication initiator protein DnaA;


Pssm-ID: 237605 [Multi-domain]  Cd Length: 617  Bit Score: 51.75  E-value: 1.06e-06
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 33286446  502 EDTEGRTGPKEGTPGSPSETPGPSPA--------GPAGDEPAESPSETPGPRPAGPAGdePAESPSETPG--PRPAGPAG 571
Cdd:PRK14086  89 DPSAGEPAPPPPHARRTSEPELPRPGrrpyegygGPRADDRPPGLPRQDQLPTARPAY--PAYQQRPEPGawPRAADDYG 166
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 33286446  572 DE--PAESPSETPGPSPAGPTRD-EPAESP-----SETPGPRP----AGPAGDEPAESPSETPGPRPA-------GPAGD 632
Cdd:PRK14086 167 WQqqRLGFPPRAPYASPASYAPEqERDREPydagrPEYDQRRRdydhPRPDWDRPRRDRTDRPEPPPGaghvhrgGPGPP 246
                        170       180       190
                 ....*....|....*....|....*....|
gi 33286446  633 EPAESPSETPGPSPAGPTRDEPAKAGEAAE 662
Cdd:PRK14086 247 ERDDAPVVPIRPSAPGPLAAQPAPAPGPGE 276
PRK07003 PRK07003
DNA polymerase III subunit gamma/tau;
399-654 1.24e-06

DNA polymerase III subunit gamma/tau;


Pssm-ID: 235906 [Multi-domain]  Cd Length: 830  Bit Score: 51.77  E-value: 1.24e-06
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 33286446  399 PGPQSASEVEKIALNLEGCALSQGSLRTGTQEVGGQDPGEAVQPCRQPLGARVADKV-RKRRKVDEGAGDSAAVASGGAQ 477
Cdd:PRK07003 383 PGARAAAAVGASAVPAVTAVTGAAGAALAPKAAAAAAATRAEAPPAAPAPPATADRGdDAADGDAPVPAKANARASADSR 462
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 33286446  478 TLALAGSPAPSGHPK---AGHSENGVEEDTEGRTGPKEGTPGSPSETPGPSPAGPAGDEPAESPSETPGPRPAGPAGDEP 554
Cdd:PRK07003 463 CDERDAQPPADSGSAsapASDAPPDAAFEPAPRAAAPSAATPAAVPDARAPAAASREDAPAAAAPPAPEARPPTPAAAAP 542
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 33286446  555 AESPSETPGP----RPAG-PAGDEPAESPSETPGPSPAGPTRDEPAESPSETPGPRPAGPAgdepaespsETPGPRPAGP 629
Cdd:PRK07003 543 AARAGGAAAAldvlRNAGmRVSSDRGARAAAAAKPAAAPAAAPKPAAPRVAVQVPTPRARA---------ATGDAPPNGA 613
                        250       260
                 ....*....|....*....|....*
gi 33286446  630 AgdePAESPSETPGPSPagPTRDEP 654
Cdd:PRK07003 614 A---RAEQAAESRGAPP--PWEDIP 633
SPT5 COG5164
Transcription elongation factor SPT5 [Transcription];
483-658 1.43e-06

Transcription elongation factor SPT5 [Transcription];


Pssm-ID: 444063 [Multi-domain]  Cd Length: 495  Bit Score: 51.18  E-value: 1.43e-06
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 33286446 483 GSPAPSGHPKAGHSENGVEEDTEGRTGPKEGTPGSPSETPGPSpAGPAGDEPAESPS-ETPGPRPAG------PAGDEPA 555
Cdd:COG5164   2 GLYGPGKTGPSDPGGVTTPAGSQGSTKPAQNQGSTRPAGNTGG-TRPAQNQGSTTPAgNTGGTRPAGnqgatgPAQNQGG 80
                        90       100       110       120       130       140       150       160
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 33286446 556 ESPSETPG-PRPAG------PAGDEPAESPSETPGpsPAGPTRDEPAESPSETPGPRPAGPAGDEPAESPSETPG--PRP 626
Cdd:COG5164  81 TTPAQNQGgTRPAGntggttPAGDGGATGPPDDGG--ATGPPDDGGSTTPPSGGSTTPPGDGGSTPPGPGSTGPGgsTTP 158
                       170       180       190
                ....*....|....*....|....*....|..
gi 33286446 627 AGPAGDEPAESPSETPGPSPAGPTRDEPAKAG 658
Cdd:COG5164 159 PGDGGSTTPPGPGGSTTPPDDGGSTTPPNKGE 190
PRK13108 PRK13108
prolipoprotein diacylglyceryl transferase; Reviewed
504-667 2.91e-06

prolipoprotein diacylglyceryl transferase; Reviewed


Pssm-ID: 237284 [Multi-domain]  Cd Length: 460  Bit Score: 50.36  E-value: 2.91e-06
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 33286446  504 TEGRTGPkEGTPGSPSETPGPSPAGPAGDEPAESPSETPGPRPAGPA----GDEPAESPSETPGPRPAGPAGDEPAESPS 579
Cdd:PRK13108 276 PKGREAP-GALRGSEYVVDEALEREPAELAAAAVASAASAVGPVGPGepnqPDDVAEAVKAEVAEVTDEVAAESVVQVAD 354
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 33286446  580 ETPGPSPAGPTRDEPA---ESPSETPGPRPAGPAGDEPAES--PSETPGPRPAGPAGDEPAESPSETPGPSPAGPtrDEP 654
Cdd:PRK13108 355 RDGESTPAVEETSEADierEQPGDLAGQAPAAHQVDAEAASaaPEEPAALASEAHDETEPEVPEKAAPIPDPAKP--DEL 432
                        170
                 ....*....|...
gi 33286446  655 AKAGEAAELQDAE 667
Cdd:PRK13108 433 AVAGPGDDPAEPD 445
PRK12323 PRK12323
DNA polymerase III subunit gamma/tau;
545-677 3.01e-06

DNA polymerase III subunit gamma/tau;


Pssm-ID: 237057 [Multi-domain]  Cd Length: 700  Bit Score: 50.64  E-value: 3.01e-06
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 33286446  545 RPAGPAGDEPAESPSETPGPRPAGPAGDEPAESPSETPGPSPAGPTRDEPAESPSETPGPRPAGPAgdePAESPSETPGP 624
Cdd:PRK12323 364 RPGQSGGGAGPATAAAAPVAQPAPAAAAPAAAAPAPAAPPAAPAAAPAAAAAARAVAAAPARRSPA---PEALAAARQAS 440
                         90       100       110       120       130
                 ....*....|....*....|....*....|....*....|....*....|...
gi 33286446  625 RPAGPAGDEPAESPSETPGPSPAGPTRDEPAKAGEAAELQDAEVESSAKSGKP 677
Cdd:PRK12323 441 ARGPGGAPAPAPAPAAAPAAAARPAAAGPRPVAAAAAAAPARAAPAAAPAPAD 493
SepH NF040712
septation protein SepH; Septation protein H (SepH) was firstly characterized in Streptomyces ...
508-651 3.34e-06

septation protein SepH; Septation protein H (SepH) was firstly characterized in Streptomyces venezuelae, and homologs were identified in Mycobacterium smegmatis. SepH contains a N-terminal DUF3071 domain and a conserved C-terminal region. It binds directly to cell division protein FtsZ to stimulate the assembly of FtsZ protofilaments.


Pssm-ID: 468676 [Multi-domain]  Cd Length: 346  Bit Score: 49.77  E-value: 3.34e-06
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 33286446  508 TGPKEGTPGSPSETPGPSPAGPAGDEPAespsETPGPRPAGPAGDEPAESPSETPGPRPAGPAGDEPAESPSETPGPSPA 587
Cdd:NF040712 193 GRPLRPLATVPRLAREPADARPEEVEPA----PAAEGAPATDSDPAEAGTPDDLASARRRRAGVEQPEDEPVGPGAAPAA 268
                         90       100       110       120       130       140
                 ....*....|....*....|....*....|....*....|....*....|....*....|....
gi 33286446  588 GPTRDEPAESPSETPGPRPAGPAGDEPAESPSetPGPRPAGPAGDEPAEsPSETPGPSPAGPTR 651
Cdd:NF040712 269 EPDEATRDAGEPPAPGAAETPEAAEPPAPAPA--APAAPAAPEAEEPAR-PEPPPAPKPKRRRR 329
kgd PRK12270
multifunctional oxoglutarate decarboxylase/oxoglutarate dehydrogenase thiamine ...
571-651 3.37e-06

multifunctional oxoglutarate decarboxylase/oxoglutarate dehydrogenase thiamine pyrophosphate-binding subunit/dihydrolipoyllysine-residue succinyltransferase subunit;


Pssm-ID: 237030 [Multi-domain]  Cd Length: 1228  Bit Score: 50.66  E-value: 3.37e-06
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 33286446   571 GDEPAESPSETPGPSPAGPTRDEPAESPSETPGPRPAGPAGDEPAESPSETPGPRPAGPAGDEPAESPSETPGPSPAGPT 650
Cdd:PRK12270   37 GPGSTAAPTAAAAAAAAAASAPAAAPAAKAPAAPAPAPPAAAAPAAPPKPAAAAAAAAAPAAPPAAAAAAAPAAAAVEDE 116

                  .
gi 33286446   651 R 651
Cdd:PRK12270  117 V 117
kgd PRK12270
multifunctional oxoglutarate decarboxylase/oxoglutarate dehydrogenase thiamine ...
513-591 3.76e-06

multifunctional oxoglutarate decarboxylase/oxoglutarate dehydrogenase thiamine pyrophosphate-binding subunit/dihydrolipoyllysine-residue succinyltransferase subunit;


Pssm-ID: 237030 [Multi-domain]  Cd Length: 1228  Bit Score: 50.27  E-value: 3.76e-06
                          10        20        30        40        50        60        70
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 33286446   513 GTPGSPSETPGPSPAGPAGDEPAESPSETPGPRPAGPAGDEPAESPSETPGPRPAGPAGDEPAESPSETPGPSPAGPTR 591
Cdd:PRK12270   39 GSTAAPTAAAAAAAAAASAPAAAPAAKAPAAPAPAPPAAAAPAAPPKPAAAAAAAAAPAAPPAAAAAAAPAAAAVEDEV 117
PRK07994 PRK07994
DNA polymerase III subunits gamma and tau; Validated
524-673 3.97e-06

DNA polymerase III subunits gamma and tau; Validated


Pssm-ID: 236138 [Multi-domain]  Cd Length: 647  Bit Score: 50.25  E-value: 3.97e-06
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 33286446  524 PSPAGPAGDEPAESPSETPGPRPAGPAGDEPAESPSETPGPRPAGPAGDEPAESPSETPGPSPAGPTRDEPAESPSETPG 603
Cdd:PRK07994 361 PAAPLPEPEVPPQSAAPAASAQATAAPTAAVAPPQAPAVPPPPASAPQQAPAVPLPETTSQLLAARQQLQRAQGATKAKK 440
                         90       100       110       120       130       140       150
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 33286446  604 PRPAGPAGDEPAESPSETPGPRPAGPAGDEPAESPSETPGPSPAGPTRDEPA-----KAGEAAELQDAEVESSAK 673
Cdd:PRK07994 441 SEPAAASRARPVNSALERLASVRPAPSALEKAPAKKEAYRWKATNPVEVKKEpvatpKALKKALEHEKTPELAAK 515
PHA03247 PHA03247
large tegument protein UL36; Provisional
506-677 4.14e-06

large tegument protein UL36; Provisional


Pssm-ID: 223021 [Multi-domain]  Cd Length: 3151  Bit Score: 50.32  E-value: 4.14e-06
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 33286446   506 GRTGPKEGTPGSPSETPGPSPAGPAgDEPAESPSETPGPR-----------PAGPAGDEPAESPsetPGPRPAGPAGDEP 574
Cdd:PHA03247 2494 AAPDPGGGGPPDPDAPPAPSRLAPA-ILPDEPVGEPVHPRmltwirgleelASDDAGDPPPPLP---PAAPPAAPDRSVP 2569
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 33286446   575 AESPSETPgPSPAGPTRDEPAESPSETPGPR-PAGPAGDEPAESPSETPGPRPAGPagDEPAespsetPGPSPAGPTRDE 653
Cdd:PHA03247 2570 PPRPAPRP-SEPAVTSRARRPDAPPQSARPRaPVDDRGDPRGPAPPSPLPPDTHAP--DPPP------PSPSPAANEPDP 2640
                         170       180
                  ....*....|....*....|....
gi 33286446   654 PAKAGEAAELQDAEVESSAKSGKP 677
Cdd:PHA03247 2641 HPPPTVPPPERPRDDPAPGRVSRP 2664
PHA03307 PHA03307
transcriptional regulator ICP4; Provisional
446-655 4.50e-06

transcriptional regulator ICP4; Provisional


Pssm-ID: 223039 [Multi-domain]  Cd Length: 1352  Bit Score: 50.17  E-value: 4.50e-06
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 33286446   446 PLGARVADKVRKRRKVDEGAGDSAAVASGGAQTLALAGSPAPSGHPKAGHSENGVEEDTE---GRTGPKEGTPGSPSETP 522
Cdd:PHA03307  735 PLVRYSPRRARARASAWDITDALFSNPSLVPAKLAEALALLEPAEPQRGAGSSPPVRAEAafrRPGRLRRSGPAADAASR 814
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 33286446   523 GPSPAGPAGDEPAESPSETPGPRPAGPAGDEPAESPSETPGPRPAGPAGDEPAESPSETPGPsPAGPTRDEPAESPSETP 602
Cdd:PHA03307  815 TASKRKSRSHTPDGGSESSGPARPPGAAARPPPARSSESSKSKPAAAGGRARGKNGRRRPRP-PEPRARPGAAAPPKAAA 893
                         170       180       190       200       210
                  ....*....|....*....|....*....|....*....|....*....|...
gi 33286446   603 GPRPAGPAGDEPAESPSETPGPRPAGpagdepaespsetpGPSPAGPTRDEPA 655
Cdd:PHA03307  894 AAPPAGAPAPRPRPAPRVKLGPMPPG--------------GPDPRGGFRRVPP 932
kgd PRK12270
multifunctional oxoglutarate decarboxylase/oxoglutarate dehydrogenase thiamine ...
531-618 6.49e-06

multifunctional oxoglutarate decarboxylase/oxoglutarate dehydrogenase thiamine pyrophosphate-binding subunit/dihydrolipoyllysine-residue succinyltransferase subunit;


Pssm-ID: 237030 [Multi-domain]  Cd Length: 1228  Bit Score: 49.50  E-value: 6.49e-06
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 33286446   531 GDEPAESPSETPGPRPAGPAGDEPAESPSETPGPRPAGPAGDEPAESPSETPGPSPAgptrdEPAESPSETPGPRPAGPA 610
Cdd:PRK12270   37 GPGSTAAPTAAAAAAAAAASAPAAAPAAKAPAAPAPAPPAAAAPAAPPKPAAAAAAA-----AAPAAPPAAAAAAAPAAA 111

                  ....*...
gi 33286446   611 GDEPAESP 618
Cdd:PRK12270  112 AVEDEVTP 119
PLN03237 PLN03237
DNA topoisomerase 2; Provisional
512-674 8.12e-06

DNA topoisomerase 2; Provisional


Pssm-ID: 215641 [Multi-domain]  Cd Length: 1465  Bit Score: 49.48  E-value: 8.12e-06
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 33286446   512 EGTPGSPSETPGPSPAGPAGDEPAESPSETPGPRPAGPAGDEPAESPSETPGPRPAGPAGDEPAESpSETPGPSPAGPTR 591
Cdd:PLN03237 1276 DSAPAQSAKMEETVKAVPARRAAARKKPLASVSVISDSDDDDDDFAVEVSLAERLKKKGGRKPAAA-NKKAAKPPAAAKK 1354
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 33286446   592 DEPAESPSE----TPGPRPAGPAGDEP-------AESPSETPGPRPAGPAGDEPAESPSETPGPSPAG-------PTRDE 653
Cdd:PLN03237 1355 RGPATVQSGqkllTEMLKPAEAIGISPekkvrkmRASPFNKKSGSVLGRAATNKETESSENVSGSSSSekdeidvSAKPR 1434
                         170       180
                  ....*....|....*....|....
gi 33286446   654 PAKA---GEAAELQDAEVESSAKS 674
Cdd:PLN03237 1435 PQRAnrkQTTYVLSDSESESADDS 1458
PRK07994 PRK07994
DNA polymerase III subunits gamma and tau; Validated
490-653 9.06e-06

DNA polymerase III subunits gamma and tau; Validated


Pssm-ID: 236138 [Multi-domain]  Cd Length: 647  Bit Score: 49.09  E-value: 9.06e-06
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 33286446  490 HPKAGHSEnGVEEDTEGRTGPKEGTPGSPSETPGPSPAGPAGDEPAESPSETPGPRPAGPAGD--------EPAESPSET 561
Cdd:PRK07994 360 HPAAPLPE-PEVPPQSAAPAASAQATAAPTAAVAPPQAPAVPPPPASAPQQAPAVPLPETTSQllaarqqlQRAQGATKA 438
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 33286446  562 PGPRPAGPAGDEPAESPSETPGPSPAGPTRDEPAESPSETPGPRPagpagDEPAESPSETPGPRPAGPAGDEPAESPSET 641
Cdd:PRK07994 439 KKSEPAAASRARPVNSALERLASVRPAPSALEKAPAKKEAYRWKA-----TNPVEVKKEPVATPKALKKALEHEKTPELA 513
                        170
                 ....*....|..
gi 33286446  642 PGPSPAGPTRDE 653
Cdd:PRK07994 514 AKLAAEAIERDP 525
PLN03209 PLN03209
translocon at the inner envelope of chloroplast subunit 62; Provisional
502-677 1.22e-05

translocon at the inner envelope of chloroplast subunit 62; Provisional


Pssm-ID: 178748 [Multi-domain]  Cd Length: 576  Bit Score: 48.38  E-value: 1.22e-05
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 33286446  502 EDTEGRTGPKEGTPGSPSETPGPSPAGPAGDEPAESPSetPGPRPAGPAgDEPAesPSETPGPRPAGPAGDEPAESPSET 581
Cdd:PLN03209 378 EDLKPPTSPIPTPPSSSPASSKSVDAVAKPAEPDVVPS--PGSASNVPE-VEPA--QVEAKKTRPLSPYARYEDLKPPTS 452
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 33286446  582 PGPSPAGPTRDEPAESPSETPGPRPAGPAGDEPAESPSeTPGPRPAGP----AGDEPAESPSET-PGPSPAGPTRDEPAK 656
Cdd:PLN03209 453 PSPTAPTGVSPSVSSTSSVPAVPDTAPATAATDAAAPP-PANMRPLSPyavyDDLKPPTSPSPAaPVGKVAPSSTNEVVK 531
                        170       180
                 ....*....|....*....|.
gi 33286446  657 AGEAAELQDAEVESSAKSGKP 677
Cdd:PLN03209 532 VGNSAPPTALADEQHHAQPKP 552
PHA02682 PHA02682
ORF080 virion core protein; Provisional
529-674 1.27e-05

ORF080 virion core protein; Provisional


Pssm-ID: 177464 [Multi-domain]  Cd Length: 280  Bit Score: 47.55  E-value: 1.27e-05
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 33286446  529 PAGDEPAESPSETPGPRPAGPAGDEPAESPSET-PGPRPAGPagdePAESPSETPGPSPAGPTRDEPAESPSET------ 601
Cdd:PHA02682  76 PSGQSPLAPSPACAAPAPACPACAPAAPAPAVTcPAPAPACP----PATAPTCPPPAVCPAPARPAPACPPSTRqcppap 151
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 33286446  602 --PGPRPAgpagdePAESPS--ETPGPRPAGPAGD------EPAESP---SETPGPSPAGPTRDEPAKAGEAAELQDAEV 668
Cdd:PHA02682 152 plPTPKPA------PAAKPIflHNQLPPPDYPAAScptietAPAASPvlePRIPDKIIDADNDDKDLIKKELADIADSVR 225

                 ....*.
gi 33286446  669 ESSAKS 674
Cdd:PHA02682 226 DLNAES 231
PHA03264 PHA03264
envelope glycoprotein D; Provisional
482-589 1.30e-05

envelope glycoprotein D; Provisional


Pssm-ID: 223029 [Multi-domain]  Cd Length: 416  Bit Score: 48.08  E-value: 1.30e-05
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 33286446  482 AGSPAPSGHPkaghsengveeDTEGRTGPKEGTPGSPSETPGPSPAGPAGDEPAESPSETPGPRPAGPAgdepaeSPSET 561
Cdd:PHA03264 272 GGSPAPPGDD-----------RPEAKPEPGPVEDGAPGRETGGEGEGPEPAGRDGAAGGEPKPGPPRPA------PDADR 334
                         90       100
                 ....*....|....*....|....*...
gi 33286446  562 PGPRPAGPAGDEPAESPSeTPGPSPAGP 589
Cdd:PHA03264 335 PEGWPSLEAITFPPPTPA-TPAVPRARP 361
PHA03264 PHA03264
envelope glycoprotein D; Provisional
506-610 1.66e-05

envelope glycoprotein D; Provisional


Pssm-ID: 223029 [Multi-domain]  Cd Length: 416  Bit Score: 47.69  E-value: 1.66e-05
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 33286446  506 GRTGPK---EGTPGSPSETP-GPSPAGPAGDEPaeSPSETPGPRPAGPAGDEPAESPsetPGPRPAGPAGDEPAESpseT 581
Cdd:PHA03264 251 GGVVPPyfeESKGYEPPPAPsGGSPAPPGDDRP--EAKPEPGPVEDGAPGRETGGEG---EGPEPAGRDGAAGGEP---K 322
                         90       100       110
                 ....*....|....*....|....*....|...
gi 33286446  582 PGPSPAGPTRDEPAESPSET----PGPRPAGPA 610
Cdd:PHA03264 323 PGPPRPAPDADRPEGWPSLEaitfPPPTPATPA 355
kgd PRK12270
multifunctional oxoglutarate decarboxylase/oxoglutarate dehydrogenase thiamine ...
550-638 2.10e-05

multifunctional oxoglutarate decarboxylase/oxoglutarate dehydrogenase thiamine pyrophosphate-binding subunit/dihydrolipoyllysine-residue succinyltransferase subunit;


Pssm-ID: 237030 [Multi-domain]  Cd Length: 1228  Bit Score: 47.96  E-value: 2.10e-05
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 33286446   550 AGDEPAESPSETPGPRPAGPAGDEPAESPSETPGPSPAGPTrdEPAESPSETPGPRPAgPAGDEPAESPSETPGPRPAGP 629
Cdd:PRK12270   34 ADYGPGSTAAPTAAAAAAAAAASAPAAAPAAKAPAAPAPAP--PAAAAPAAPPKPAAA-AAAAAAPAAPPAAAAAAAPAA 110

                  ....*....
gi 33286446   630 AGDEPAESP 638
Cdd:PRK12270  111 AAVEDEVTP 119
PRK14950 PRK14950
DNA polymerase III subunits gamma and tau; Provisional
564-668 2.81e-05

DNA polymerase III subunits gamma and tau; Provisional


Pssm-ID: 237864 [Multi-domain]  Cd Length: 585  Bit Score: 47.11  E-value: 2.81e-05
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 33286446  564 PRPAgpagdePAESPSETPGPSPAGPTRDepaesPSETPGP---RPAGPAGDEPAESPSETPGPRPAGPAGDEPAESPSE 640
Cdd:PRK14950 362 PVPA------PQPAKPTAAAPSPVRPTPA-----PSTRPKAaaaANIPPKEPVRETATPPPVPPRPVAPPVPHTPESAPK 430
                         90       100       110
                 ....*....|....*....|....*....|.
gi 33286446  641 TPG---PSPAGPTRDEPAKAGEAAELQDAEV 668
Cdd:PRK14950 431 LTRaaiPVDEKPKYTPPAPPKEEEKALIADG 461
PRK14950 PRK14950
DNA polymerase III subunits gamma and tau; Provisional
514-600 2.81e-05

DNA polymerase III subunits gamma and tau; Provisional


Pssm-ID: 237864 [Multi-domain]  Cd Length: 585  Bit Score: 47.11  E-value: 2.81e-05
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 33286446  514 TPGSPSETPGPSPAGPAGDEPAESPSETPGP---RPAGPAGDEPAESPSETPGPRPAGPAGDEPAESPSETPG---PSPA 587
Cdd:PRK14950 361 VPVPAPQPAKPTAAAPSPVRPTPAPSTRPKAaaaANIPPKEPVRETATPPPVPPRPVAPPVPHTPESAPKLTRaaiPVDE 440
                         90
                 ....*....|...
gi 33286446  588 GPTRDEPAESPSE 600
Cdd:PRK14950 441 KPKYTPPAPPKEE 453
SAV_2336_NTERM NF041121
SAV_2336 family N-terminal domain; This HMM describes an N-terminal domain shared by SAV_2336 ...
514-606 2.85e-05

SAV_2336 family N-terminal domain; This HMM describes an N-terminal domain shared by SAV_2336 (BAC70047.1) whose C-terminal region suggests restriction enzyme activity (PMID: 18456708), and with other proteins with unrelated C-terminal regions. A member protein was also identified in a kanamycin biosynthetic gene cluster (PMID:16766657), while N-terminal regions of two other member proteins were named Trypco1 in a bioinformatic study (PMID:32101166) of predicted bacterial conflict systems.


Pssm-ID: 469044 [Multi-domain]  Cd Length: 473  Bit Score: 46.92  E-value: 2.85e-05
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 33286446  514 TPGSPSETPGPSPAGPAGDEPAESPSETPGPRPAGPAGDEPAESPSETPGPRPAGPAGDepaesPSETPGPSPAGPTRDE 593
Cdd:NF041121  15 MGRAAAPPSPEGPAPTAASQPATPPPPAAPPSPPGDPPEPPAPEPAPLPAPYPGSLAPP-----PPPPPGPAGAAPGAAL 89
                         90
                 ....*....|...
gi 33286446  594 PAESPSETPGPRP 606
Cdd:NF041121  90 PVRVPAPPALPNP 102
PRK14951 PRK14951
DNA polymerase III subunits gamma and tau; Provisional
510-618 3.20e-05

DNA polymerase III subunits gamma and tau; Provisional


Pssm-ID: 237865 [Multi-domain]  Cd Length: 618  Bit Score: 47.02  E-value: 3.20e-05
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 33286446  510 PKEGTPGSPSETPGPSPAGPAGDEPAE-----SPSETPGPRPAGPAGDEPAESPsetPGPRPAGPAGDEPAESPSETPGP 584
Cdd:PRK14951 381 PARPEAAAPAAAPVAQAAAAPAPAAAPaaaasAPAAPPAAAPPAPVAAPAAAAP---AAAPAAAPAAVALAPAPPAQAAP 457
                         90       100       110
                 ....*....|....*....|....*....|....*
gi 33286446  585 SP-AGPTRDEPAESPSETPGPRPAGPAGDEPAESP 618
Cdd:PRK14951 458 ETvAIPVRVAPEPAVASAAPAPAAAPAAARLTPTE 492
PHA03307 PHA03307
transcriptional regulator ICP4; Provisional
530-675 3.22e-05

transcriptional regulator ICP4; Provisional


Pssm-ID: 223039 [Multi-domain]  Cd Length: 1352  Bit Score: 47.47  E-value: 3.22e-05
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 33286446   530 AGDEPAESPSETPGPRPAGPAGDEPAESPSETPGPRPAGPAGDEPAESPSETPGPSPAGPTRDEPAESPSETPGPRPAGP 609
Cdd:PHA03307   16 EGGEFFPRPPATPGDAADDLLSGSQGQLVSDSAELAAVTVVAGAAACDRFEPPTGPPPGPGTEAPANESRSTPTWSLSTL 95
                          90       100       110       120       130       140       150
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 33286446   610 AGDEPAESPSETPGPRPAGPAgdEPAESPSETPGPSPA----------GPTRDEPAKAGEAAELQDAEVESSAKSG 675
Cdd:PHA03307   96 APASPAREGSPTPPGPSSPDP--PPPTPPPASPPPSPApdlsemlrpvGSPGPPPAASPPAAGASPAAVASDAASS 169
kgd PRK12270
multifunctional oxoglutarate decarboxylase/oxoglutarate dehydrogenase thiamine ...
539-621 3.85e-05

multifunctional oxoglutarate decarboxylase/oxoglutarate dehydrogenase thiamine pyrophosphate-binding subunit/dihydrolipoyllysine-residue succinyltransferase subunit;


Pssm-ID: 237030 [Multi-domain]  Cd Length: 1228  Bit Score: 47.19  E-value: 3.85e-05
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 33286446   539 SETPGPRPAGPAGDEPAESPSETPGPRPAGPAGDEPAESPSETPGPSPAGPTRDEPAESPSETPGPRPAGPAGDEPAESP 618
Cdd:PRK12270   35 DYGPGSTAAPTAAAAAAAAAASAPAAAPAAKAPAAPAPAPPAAAAPAAPPKPAAAAAAAAAPAAPPAAAAAAAPAAAAVE 114

                  ...
gi 33286446   619 SET 621
Cdd:PRK12270  115 DEV 117
PHA03307 PHA03307
transcriptional regulator ICP4; Provisional
504-658 4.09e-05

transcriptional regulator ICP4; Provisional


Pssm-ID: 223039 [Multi-domain]  Cd Length: 1352  Bit Score: 47.09  E-value: 4.09e-05
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 33286446   504 TEGRTGPKEGTPGSPSETPGPSPAGPAGDEPAESPseTPGPRPAGPAGD-EPAESPSETPGPRPAGPAGDEPAESPSETP 582
Cdd:PHA03307  764 VPAKLAEALALLEPAEPQRGAGSSPPVRAEAAFRR--PGRLRRSGPAADaASRTASKRKSRSHTPDGGSESSGPARPPGA 841
                          90       100       110       120       130       140       150
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 33286446   583 GPSPAGPTRDEPAESPSETPGPRPAGPAGDEPAES--PSETPGPRPAGPAGDEPAESPSETPGPSPAGPTRDEPAKAG 658
Cdd:PHA03307  842 AARPPPARSSESSKSKPAAAGGRARGKNGRRRPRPpePRARPGAAAPPKAAAAAPPAGAPAPRPRPAPRVKLGPMPPG 919
PHA03269 PHA03269
envelope glycoprotein C; Provisional
538-645 4.09e-05

envelope glycoprotein C; Provisional


Pssm-ID: 165527 [Multi-domain]  Cd Length: 566  Bit Score: 46.65  E-value: 4.09e-05
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 33286446  538 PSETPGPRPAGPAGDEPAESPSETPG--PRPAGPAGDEPAESPSETPGPSPAGPTRDEPAESPSETPGPRPagpagdEPA 615
Cdd:PHA03269  40 PDPAPAPHQAASRAPDPAVAPTSAASrkPDLAQAPTPAASEKFDPAPAPHQAASRAPDPAVAPQLAAAPKP------DAA 113
                         90       100       110
                 ....*....|....*....|....*....|
gi 33286446  616 ESPSETPGPRPAgpAGDEPAESPSETPGPS 645
Cdd:PHA03269 114 EAFTSAAQAHEA--PADAGTSAASKKPDPA 141
PRK10263 PRK10263
DNA translocase FtsK; Provisional
475-675 4.14e-05

DNA translocase FtsK; Provisional


Pssm-ID: 236669 [Multi-domain]  Cd Length: 1355  Bit Score: 47.00  E-value: 4.14e-05
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 33286446   475 GAQTLALAGSPAPSGHPKAGHSENGVEEDTEGRTGPKEGTPGSPSETPGPSPAGPAGDEPAESPSETPGPRPA------- 547
Cdd:PRK10263  365 GPQTGEPVIAPAPEGYPQQSQYAQPAVQYNEPLQQPVQPQQPYYAPAAEQPAQQPYYAPAPEQPAQQPYYAPApeqpvag 444
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 33286446   548 GPAGDEPAESP-SETPGPRPAGPAGDEPAESPSETPGPSPAGPTRDEPAESPSETPGPRPAGPAGDEPAESPSE------ 620
Cdd:PRK10263  445 NAWQAEEQQSTfAPQSTYQTEQTYQQPAAQEPLYQQPQPVEQQPVVEPEPVVEETKPARPPLYYFEEVEEKRARereqla 524
                         170       180       190       200       210
                  ....*....|....*....|....*....|....*....|....*....|....*...
gi 33286446   621 ---TPGPRPAgpAGDEPAESPSETPGPSPAGPTRDEPAKAGEAAELQDAEVESSAKSG 675
Cdd:PRK10263  525 awyQPIPEPV--KEPEPIKSSLKAPSVAAVPPVEAAAAVSPLASGVKKATLATGAAAT 580
PHA03307 PHA03307
transcriptional regulator ICP4; Provisional
448-621 4.34e-05

transcriptional regulator ICP4; Provisional


Pssm-ID: 223039 [Multi-domain]  Cd Length: 1352  Bit Score: 47.09  E-value: 4.34e-05
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 33286446   448 GARVADKVRKRRKVDEGAGDSAAVASGGAQTLALAGSPAPSGHPKAGHSENGVEEDTEGRTGPKEGTPGSPSETPGPSPA 527
Cdd:PHA03307  765 PAKLAEALALLEPAEPQRGAGSSPPVRAEAAFRRPGRLRRSGPAADAASRTASKRKSRSHTPDGGSESSGPARPPGAAAR 844
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 33286446   528 GPAGDEPAESPSETPGPRPAGPAGDEPAESPSETPGPRPAGPAGDEPAESPSETPGPSPAGPTRDEPAESPSETPGPRPA 607
Cdd:PHA03307  845 PPPARSSESSKSKPAAAGGRARGKNGRRRPRPPEPRARPGAAAPPKAAAAAPPAGAPAPRPRPAPRVKLGPMPPGGPDPR 924
                         170
                  ....*....|....*....
gi 33286446   608 G-----PAGDEPAESPSET 621
Cdd:PHA03307  925 GgfrrvPPGDLHTPAPSAA 943
PHA01929 PHA01929
putative scaffolding protein
526-666 4.35e-05

putative scaffolding protein


Pssm-ID: 177328  Cd Length: 306  Bit Score: 46.20  E-value: 4.35e-05
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 33286446  526 PAGPAGDEPAESPSETPGPRPAGPAGDEPAESPSETPGPRPAGPAGDEPAESPSE--TPGPSPAGPTRDEPAESPSETPG 603
Cdd:PHA01929   9 PPGLAGLVANVPPAAAPTPQPNPVIQPQAPVQPGQPGAPQQLAIPTQQPQPVPTSamTPHVVQQAPAQPAPAAPPAAGAA 88
                         90       100       110       120       130       140
                 ....*....|....*....|....*....|....*....|....*....|....*....|....
gi 33286446  604 PRPAGPAGDEPAESPSETPGPRPAGPAGDEPAESPSETPGPSPAGPTRDEPAKA-GEAAELQDA 666
Cdd:PHA01929  89 LPEALEVPPPPAFTPNGEIVGTLAGNLEGDPQLAPSVSYLEAFSGLDKLDTVRAfGKAAENRDP 152
KLF14_N cd21576
N-terminal domain of Kruppel-like factor 14; Kruppel-like factor 14 (KLF14; also known as ...
485-630 4.38e-05

N-terminal domain of Kruppel-like factor 14; Kruppel-like factor 14 (KLF14; also known as Krueppel-like factor 14 or basic transcription element-binding protein 5/BTEB5) is a protein that in humans is encoded by the KLF14 gene. KLF14 regulates the transcription of various genes, including TGFbetaRII (the type II receptor for TGFbeta). KLF14 is expressed in many tissues, lacks introns, and is subject to parent-specific expression. It also appears to be a master regulator of gene expression in adipose tissue. KLF14 is associated with coronary artery disease, hypercholesterolemia, and type 2 diabetes. KLF9, KLF10, KLF11, KLF13, KLF14, and KLF16 share a conserved alpha-helical motif AA/VXXL that mediates their binding to Sin3A and their activities as transcriptional repressors. KLF14 belongs to a family of proteins, called the Specificity Protein (SP)/KLF family, characterized by a C-terminal DNA-binding domain of 81 amino acids consisting of three Kruppel-like C2H2 zinc fingers. These factors bind to a loose consensus motif, namely NNRCRCCYY (where N is any nucleotide; R is A/G, and Y is C/T), such as the recurring motifs in GC and GT boxes (5'-GGGGCGGGG-3' and 5-GGTGTGGGG-3') that are present in promoters and more distal regulatory elements of mammalian genes. Members of the KLF family can act as activators or repressors of transcription depending on cell and promoter context. KLFs regulate various cellular functions, such as proliferation, differentiation, and apoptosis, as well as the development and homeostasis of several types of tissue. In addition to the C-terminal DNA-binding domain, each KLF also has a unique N-terminal activation/repression domain that confers specificity and allows it to bind specifically to a certain partner, leading to distinct activities in vivo. This model represents the N-terminal domain of KLF14.


Pssm-ID: 409238 [Multi-domain]  Cd Length: 195  Bit Score: 44.81  E-value: 4.38e-05
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 33286446 485 PAPSGHPKAGHSENGVEEDTEGRTGPkeGTPGSPSETPGPSPAGPAGDEPAESP-------------------SETPGPR 545
Cdd:cd21576  29 PDPEGAGGAAGSEVGAAPPESALPGP--GPPGPAWVPPLLQVPAPSPGAGGAAPhllaasvladlrggagegsREDSGEA 106
                        90       100       110       120       130       140       150       160
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 33286446 546 P-AGPAGDEPAESPSETPGPRPAGPAGDEPAESPSETPGpSPAGPTRDEPAESPSEtPGPRPAGPAGDEPAESPSETPGP 624
Cdd:cd21576 107 PrASSGSSDPARGSSPTLGSEPAPASGEDAVSGPESSFG-APAIPSAPAAPGAPAV-SGEVPGGAPGAGPAPAAGPAPRR 184

                ....*.
gi 33286446 625 RPAGPA 630
Cdd:cd21576 185 RPVTPA 190
PHA03264 PHA03264
envelope glycoprotein D; Provisional
523-649 4.44e-05

envelope glycoprotein D; Provisional


Pssm-ID: 223029 [Multi-domain]  Cd Length: 416  Bit Score: 46.54  E-value: 4.44e-05
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 33286446  523 GPSPAGPAGDEPAESPSETPGPRPAGPAGDEPaeSPSETPGPRPAGPAGDEPAESPsetPGPSPAGPTRDEPAEspsetP 602
Cdd:PHA03264 252 GVVPPYFEESKGYEPPPAPSGGSPAPPGDDRP--EAKPEPGPVEDGAPGRETGGEG---EGPEPAGRDGAAGGE-----P 321
                         90       100       110       120
                 ....*....|....*....|....*....|....*....|....*..
gi 33286446  603 GPRPAGPAgdepaeSPSETPGPRPAGPAGDEPAESPSeTPGPSPAGP 649
Cdd:PHA03264 322 KPGPPRPA------PDADRPEGWPSLEAITFPPPTPA-TPAVPRARP 361
PRK12373 PRK12373
NADH-quinone oxidoreductase subunit E;
536-677 4.79e-05

NADH-quinone oxidoreductase subunit E;


Pssm-ID: 237082 [Multi-domain]  Cd Length: 400  Bit Score: 46.33  E-value: 4.79e-05
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 33286446  536 ESPSETPGPRpAGPAGDEPAESPSE--TPGPRPAGPAGDEPAES-------PSETPGPSPAGPTRDEPAESPSETPGPRP 606
Cdd:PRK12373 173 KGPVVKPGPQ-IGRYASEPAGGLTSltEEAGKARYNASKALAEDigdtvkrIDGTEVPLLAPWQGDAAPVPPSEAARPKS 251
                         90       100       110       120       130       140       150
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 33286446  607 AGPAGDEPAESPSETPGPrPAGPAGDEPAESPSETPGPSPAgPTRDEPAKAGEAAELQDAEVE--SSAKSGKP 677
Cdd:PRK12373 252 ADAETNAALKTPATAPKA-AAKNAKAPEAQPVSGTAAAEPA-PKEAAKAAAAAAKPALEDKPRplGIARPGGA 322
Treacle pfam03546
Treacher Collins syndrome protein Treacle;
482-655 5.20e-05

Treacher Collins syndrome protein Treacle;


Pssm-ID: 460967 [Multi-domain]  Cd Length: 531  Bit Score: 46.22  E-value: 5.20e-05
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 33286446   482 AGSPAPSGHPKAGHSENGVEEDTEGRTgpkegtPGSPSETPGPSPAGPAGDEPAESPSETPGPRPAGPAGDEPAESPSET 561
Cdd:pfam03546  82 AAAQAQAGKPEEDSESSSEESDSDGET------PAAATLTTSPAQVKPLGKNSQVRPASTVGKGPSGKGANPAPPGKAGS 155
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 33286446   562 PGPRPAGPAGDEPAESPSETPGPSPAGPTRDEPAESPSETPGPRPAGPAGDEPAESPSETPGP--------RPAGPAGDE 633
Cdd:pfam03546 156 AAPLVQVGKKEEDSESSSEESDSEGEAPPAATQAKPSGKILQVRPASGPAKGAAPAPPQKAGPvatqvkaeRSKEDSESS 235
                         170       180
                  ....*....|....*....|..
gi 33286446   634 PAESPSETPGPSPAGPTRDEPA 655
Cdd:pfam03546 236 EESSDSEEEAPAAATPAQAKPA 257
SAV_2336_NTERM NF041121
SAV_2336 family N-terminal domain; This HMM describes an N-terminal domain shared by SAV_2336 ...
563-651 5.36e-05

SAV_2336 family N-terminal domain; This HMM describes an N-terminal domain shared by SAV_2336 (BAC70047.1) whose C-terminal region suggests restriction enzyme activity (PMID: 18456708), and with other proteins with unrelated C-terminal regions. A member protein was also identified in a kanamycin biosynthetic gene cluster (PMID:16766657), while N-terminal regions of two other member proteins were named Trypco1 in a bioinformatic study (PMID:32101166) of predicted bacterial conflict systems.


Pssm-ID: 469044 [Multi-domain]  Cd Length: 473  Bit Score: 46.15  E-value: 5.36e-05
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 33286446  563 GPRPAGPAGDEPAESPSETPGPSPAGPTRDEPAESPSETPGPRPAGPAGDEPAESPSE---TPGPRPAGPAGDEPAESPS 639
Cdd:NF041121  16 GRAAAPPSPEGPAPTAASQPATPPPPAAPPSPPGDPPEPPAPEPAPLPAPYPGSLAPPpppPPGPAGAAPGAALPVRVPA 95
                         90
                 ....*....|..
gi 33286446  640 ETPGPSPAGPTR 651
Cdd:NF041121  96 PPALPNPLELAR 107
PHA03169 PHA03169
hypothetical protein; Provisional
463-646 5.43e-05

hypothetical protein; Provisional


Pssm-ID: 223003 [Multi-domain]  Cd Length: 413  Bit Score: 46.12  E-value: 5.43e-05
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 33286446  463 EGAGDSAAVASGGAQTLALAGSPAPSGhpkaGHSENGVEEDTEGRTGPKEGTPGSPSEtpgpspagPAGDEPAESPSETP 542
Cdd:PHA03169  98 ESVGSPTPSPSGSAEELASGLSPENTS----GSSPESPASHSPPPSPPSHPGPHEPAP--------PESHNPSPNQQPSS 165
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 33286446  543 GPRPAGPAGDEPAESPSETPGPR-PAGPAGDEPAESPSE-TPGPSPAGPTRDEPAESPSetPGPRPAGPAGDEPAESPSE 620
Cdd:PHA03169 166 FLQPSHEDSPEEPEPPTSEPEPDsPGPPQSETPTSSPPPqSPPDEPGEPQSPTPQQAPS--PNTQQAVEHEDEPTEPERE 243
                        170       180
                 ....*....|....*....|....*..
gi 33286446  621 TPG-PRPAGPAGDEPAESPSETPGPSP 646
Cdd:PHA03169 244 GPPfPGHRSHSYTVVGWKPSTRPGGVP 270
SepH NF040712
septation protein SepH; Septation protein H (SepH) was firstly characterized in Streptomyces ...
523-677 5.58e-05

septation protein SepH; Septation protein H (SepH) was firstly characterized in Streptomyces venezuelae, and homologs were identified in Mycobacterium smegmatis. SepH contains a N-terminal DUF3071 domain and a conserved C-terminal region. It binds directly to cell division protein FtsZ to stimulate the assembly of FtsZ protofilaments.


Pssm-ID: 468676 [Multi-domain]  Cd Length: 346  Bit Score: 45.91  E-value: 5.58e-05
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 33286446  523 GPSPAGPAgdepaesPSETPGPRPAGPAGDEPAESPSETPGPRPAgpagdePAESPSETPGPSPAGPTRDEPAESPSETP 602
Cdd:NF040712 189 DPDFGRPL-------RPLATVPRLAREPADARPEEVEPAPAAEGA------PATDSDPAEAGTPDDLASARRRRAGVEQP 255
                         90       100       110       120       130       140       150
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 33286446  603 GPRPAGPAGDEPAESPSETPGPRPAGPAGDEPAESPSETPGPSPAGPTRD-EPAKAGEAAELQDAEVESSAKSGKP 677
Cdd:NF040712 256 EDEPVGPGAAPAAEPDEATRDAGEPPAPGAAETPEAAEPPAPAPAAPAAPaAPEAEEPARPEPPPAPKPKRRRRRA 331
PTZ00449 PTZ00449
104 kDa microneme/rhoptry antigen; Provisional
395-677 6.13e-05

104 kDa microneme/rhoptry antigen; Provisional


Pssm-ID: 185628 [Multi-domain]  Cd Length: 943  Bit Score: 46.22  E-value: 6.13e-05
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 33286446  395 PPTEPGPQSASEVEKIALNLEGCALSQGSLRTGTQEVGGQDPGEAVQ--PCRQPLGARVADKVRKRRKVDEGAGDSAAVA 472
Cdd:PTZ00449 520 PPKAPGDKEGEEGEHEDSKESDEPKEGGKPGETKEGEVGKKPGPAKEhkPSKIPTLSKKPEFPKDPKHPKDPEEPKKPKR 599
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 33286446  473 SGGAQTLALAGSPAPSGHPKAGHSENGVEEDTEGRTGPKEGTPGSPSETPGP----SPAGPAGDEPAESPS--------- 539
Cdd:PTZ00449 600 PRSAQRPTRPKSPKLPELLDIPKSPKRPESPKSPKRPPPPQRPSSPERPEGPkiikSPKPPKSPKPPFDPKfkekfyddy 679
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 33286446  540 --------ETPGPRPAGPAGDEP-AESPSETPG-----PRPAGPAGDEPAESPSETPG----PSPAGPTRDEPAESPS-- 599
Cdd:PTZ00449 680 ldaaakskETKTTVVLDESFESIlKETLPETPGtpfttPRPLPPKLPRDEEFPFEPIGdpdaEQPDDIEFFTPPEEERtf 759
                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 33286446  600 --ETPGPRPAGPAGDEPAESP---SETPGPRPAGPAGDEPAESPSETPGPSPAGPTRdepAKAGEAAELQDAEVESSA-- 672
Cdd:PTZ00449 760 fhETPADTPLPDILAEEFKEEdihAETGEPDEAMKRPDSPSEHEDKPPGDHPSLPKK---RHRLDGLALSTTDLESDAgr 836

                 ....*....
gi 33286446  673 ----KSGKP 677
Cdd:PTZ00449 837 iakdASGKI 845
kgd PRK12270
multifunctional oxoglutarate decarboxylase/oxoglutarate dehydrogenase thiamine ...
591-671 7.48e-05

multifunctional oxoglutarate decarboxylase/oxoglutarate dehydrogenase thiamine pyrophosphate-binding subunit/dihydrolipoyllysine-residue succinyltransferase subunit;


Pssm-ID: 237030 [Multi-domain]  Cd Length: 1228  Bit Score: 46.04  E-value: 7.48e-05
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 33286446   591 RDEPAESPSETPGPRPAGPAGDEPAESPSETPGPRPAGPAGDEPAESPSETPGPSPA-GPTRDEPAKAGEAAELQDAEVE 669
Cdd:PRK12270   37 GPGSTAAPTAAAAAAAAAASAPAAAPAAKAPAAPAPAPPAAAAPAAPPKPAAAAAAAaAPAAPPAAAAAAAPAAAAVEDE 116

                  ..
gi 33286446   670 SS 671
Cdd:PRK12270  117 VT 118
PRK13108 PRK13108
prolipoprotein diacylglyceryl transferase; Reviewed
399-571 7.98e-05

prolipoprotein diacylglyceryl transferase; Reviewed


Pssm-ID: 237284 [Multi-domain]  Cd Length: 460  Bit Score: 45.74  E-value: 7.98e-05
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 33286446  399 PGPQSASE-VEKIALNLEGCALSQGSLRTGTQEVGGQDPGEAVQPCRqplGARVADKVRKRRKVDEGAGDSAAVASGGAQ 477
Cdd:PRK13108 282 PGALRGSEyVVDEALEREPAELAAAAVASAASAVGPVGPGEPNQPDD---VAEAVKAEVAEVTDEVAAESVVQVADRDGE 358
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 33286446  478 TlalAGSPAPSGHPKAGHSENGvEEDTEGRTGPKE---GTPGSPSETPGPSPAGPAGDEPAESPSETPGPRPagpagDEP 554
Cdd:PRK13108 359 S---TPAVEETSEADIEREQPG-DLAGQAPAAHQVdaeAASAAPEEPAALASEAHDETEPEVPEKAAPIPDP-----AKP 429
                        170
                 ....*....|....*..
gi 33286446  555 AESPSETPGPRPAGPAG 571
Cdd:PRK13108 430 DELAVAGPGDDPAEPDG 446
kgd PRK12270
multifunctional oxoglutarate decarboxylase/oxoglutarate dehydrogenase thiamine ...
579-664 8.22e-05

multifunctional oxoglutarate decarboxylase/oxoglutarate dehydrogenase thiamine pyrophosphate-binding subunit/dihydrolipoyllysine-residue succinyltransferase subunit;


Pssm-ID: 237030 [Multi-domain]  Cd Length: 1228  Bit Score: 46.04  E-value: 8.22e-05
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 33286446   579 SETPGPSPAGPTRDEPAESPSETPGPRPAGPAGDEPAESPSETPGPrPAGPAgdePAESPSETPGPSPAGPTRDEPAKAG 658
Cdd:PRK12270   35 DYGPGSTAAPTAAAAAAAAAASAPAAAPAAKAPAAPAPAPPAAAAP-AAPPK---PAAAAAAAAAPAAPPAAAAAAAPAA 110

                  ....*.
gi 33286446   659 EAAELQ 664
Cdd:PRK12270  111 AAVEDE 116
PRK12678 PRK12678
transcription termination factor Rho; Provisional
459-618 8.70e-05

transcription termination factor Rho; Provisional


Pssm-ID: 237171 [Multi-domain]  Cd Length: 672  Bit Score: 45.67  E-value: 8.70e-05
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 33286446  459 RKVDEGAGDSAAVASGGAQTLALAGSPAPSGHPKAGHSENGVEEDTEGRTGPKEGTPGSPSETPGPSPAGPAGDEPAESP 538
Cdd:PRK12678  47 RKGELIAAIKEARGGGAAAAAATPAAPAAAARRAARAAAAARQAEQPAAEAAAAKAEAAPAARAAAAAAAEAASAPEAAQ 126
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 33286446  539 SETPGPRPAGPAGDEPAESPSETPGPRPAGPAGDEPAESPSETPGPSPAGPTRDEPAESPSETPGPRPAGPAGDEPAESP 618
Cdd:PRK12678 127 ARERRERGEAARRGAARKAGEGGEQPATEARADAAERTEEEERDERRRRGDREDRQAEAERGERGRREERGRDGDDRDRR 206
motB PRK05996
MotB family protein;
485-675 9.52e-05

MotB family protein;


Pssm-ID: 235665 [Multi-domain]  Cd Length: 423  Bit Score: 45.46  E-value: 9.52e-05
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 33286446  485 PAPSGHPKAGHSENGVEEDTEGRTGPKEGTPGSPSETPGPSPAgPAGDEP---------------AESPSETPGPRPAGP 549
Cdd:PRK05996  78 PSEKGLKDPVDGAEGEQKPGKSKFEEDQRVEGSSAVTGDDTTR-TSGDQTnyseadlfrnpyavlAEIAQEVGQQANVSA 156
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 33286446  550 AGDEPAespsETPGPRpAGPAGDEPAESP------------SETPGPSPAGPTRDEPAESPSETPGPRPAGPAGDEPAES 617
Cdd:PRK05996 157 KGDGGA----AQSGPA-TGADGGEAYRDPfdpdfwskqvevTTAGDLLPPGQAREQAQGAKSATAAPATVPQAAPLPQAQ 231
                        170       180       190       200       210
                 ....*....|....*....|....*....|....*....|....*....|....*...
gi 33286446  618 PSETpgPRPAGPAGDEPAESPSETPGPSPAGPTRDEPAKAGEAAELQDAEVESSAKSG 675
Cdd:PRK05996 232 PKKA--ATEEELIADAKKAATGEPAANAAKAAKPEPMPDDQQKEAEQLQAAIAQAIGG 287
DUF4045 pfam13254
Domain of unknown function (DUF4045); This presumed domain is functionally uncharacterized. ...
506-650 1.03e-04

Domain of unknown function (DUF4045); This presumed domain is functionally uncharacterized. This domain family is found in bacteria and eukaryotes, and is typically between 384 and 430 amino acids in length.


Pssm-ID: 433066 [Multi-domain]  Cd Length: 415  Bit Score: 45.16  E-value: 1.03e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 33286446   506 GRTGP-KEGTPGSPSETPGPSPAGPAGDEPaeSPSETPGPRPAGPAGDEPAESPSETPGPRPAGPAGDEPAESPSETPGP 584
Cdd:pfam13254 195 GRPNSfKEVTPVGLMRSPAPGGHSKSPSVS--GISADSSPTKEEPSEEADTLSTDKEQSPAPTSASEPPPKTKELPKDSE 272
                          90       100       110       120       130       140
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 33286446   585 SPAGPTRDEPAESPSETPGPrPAGPAGDEPAESPSETpgPRPAGPAGDEPAESPSETPGPSPAGPT 650
Cdd:pfam13254 273 EPAAPSKSAEASTEKKEPDT-ESSPETSSEKSAPSLL--SPVSKASIDKPLSSPDRDPLSPKPKPQ 335
DLIC pfam05783
Dynein light intermediate chain (DLIC); This family consists of several eukaryotic dynein ...
567-663 1.14e-04

Dynein light intermediate chain (DLIC); This family consists of several eukaryotic dynein light intermediate chain proteins. The light intermediate chains (LICs) of cytoplasmic dynein consist of multiple isoforms, which undergo post-translational modification to produce a large number of species. DLIC1 is known to be involved in assembly, organization, and function of centrosomes and mitotic spindles when bound to pericentrin. DLIC2 is a subunit of cytoplasmic dynein 2 that may play a role in maintaining Golgi organization by binding cytoplasmic dynein 2 to its Golgi-associated cargo.


Pssm-ID: 368612  Cd Length: 468  Bit Score: 45.22  E-value: 1.14e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 33286446   567 AGPAGDEPAESPSETPGPSPAGPTRDEPAESPSETPGPRPAGPAGDEPAESPSE--------------TPGPRPAGPAGd 632
Cdd:pfam05783 344 QPATPTRGVESPARSPSGSPRTTNRSGPANVASVSPQTSVKKIDPNMKPGAASEgvlanffnsllskkTGSPGGGSPGG- 422
                          90       100       110
                  ....*....|....*....|....*....|.
gi 33286446   633 ePAESPSETPGPSPAGPTRDEPAKAGEAAEL 663
Cdd:pfam05783 423 -GTGSGRGSNVQDSAKKSGQKPVLTDVQAEL 452
SAV_2336_NTERM NF041121
SAV_2336 family N-terminal domain; This HMM describes an N-terminal domain shared by SAV_2336 ...
535-626 1.15e-04

SAV_2336 family N-terminal domain; This HMM describes an N-terminal domain shared by SAV_2336 (BAC70047.1) whose C-terminal region suggests restriction enzyme activity (PMID: 18456708), and with other proteins with unrelated C-terminal regions. A member protein was also identified in a kanamycin biosynthetic gene cluster (PMID:16766657), while N-terminal regions of two other member proteins were named Trypco1 in a bioinformatic study (PMID:32101166) of predicted bacterial conflict systems.


Pssm-ID: 469044 [Multi-domain]  Cd Length: 473  Bit Score: 44.99  E-value: 1.15e-04
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 33286446  535 AESPSETPGPRPAGPAGDEPAESPSETPGPRPAGPAGDEPAESPSETPGPSPAGPTRDepaesPSETPGPRPAGPAGDEP 614
Cdd:NF041121  16 GRAAAPPSPEGPAPTAASQPATPPPPAAPPSPPGDPPEPPAPEPAPLPAPYPGSLAPP-----PPPPPGPAGAAPGAALP 90
                         90
                 ....*....|..
gi 33286446  615 AESPSETPGPRP 626
Cdd:NF041121  91 VRVPAPPALPNP 102
PLN02217 PLN02217
probable pectinesterase/pectinesterase inhibitor
513-599 1.35e-04

probable pectinesterase/pectinesterase inhibitor


Pssm-ID: 215130 [Multi-domain]  Cd Length: 670  Bit Score: 45.08  E-value: 1.35e-04
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 33286446  513 GTPGSPSETPGPSPAGPAGDEPAESPSETPGPRPAGPAG--DEPAESPSETPGPRPAGPAGDepAESPSETPGpSPAGPT 590
Cdd:PLN02217 564 GNPGSTNSTPTGSAASSNTTFSSDSPSTVVAPSTSPPAGhlGSPPATPSKIVSPSTSPPASH--LGSPSTTPS-SPESSI 640

                 ....*....
gi 33286446  591 RDEPAESPS 599
Cdd:PLN02217 641 KVASTETAS 649
PspC_subgroup_2 NF033839
pneumococcal surface protein PspC, LPXTG-anchored form; The pneumococcal surface protein PspC, ...
484-677 1.41e-04

pneumococcal surface protein PspC, LPXTG-anchored form; The pneumococcal surface protein PspC, as described in Streptococcus pneumoniae, is a repetitive and highly variable protein, recognized by a conserved N-terminal domain and also by genomic location. This form, subgroup 2, is anchored covalently after cleavage by sortase at a C-terminal LPXTG site. The other form, subgroup 1, has variable numbers of a choline-binding repeat in the C-terminal region, and is also known as choline-binding protein A.


Pssm-ID: 468202 [Multi-domain]  Cd Length: 557  Bit Score: 45.14  E-value: 1.41e-04
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 33286446  484 SPAPSGHPKAGHSENGV--EEDTEGRTGPKEGTPGSPSETPGPSPAGPAGDEPAES--PSETPGPRPAGPAGDEPAESPS 559
Cdd:NF033839 283 TPKEPGNKKPSAPKPGMqpSPQPEKKEVKPEPETPKPEVKPQLEKPKPEVKPQPEKpkPEVKPQLETPKPEVKPQPEKPK 362
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 33286446  560 ETPGPRPAGPAGDEPAE----SPSETPGPSPAGPTRDEPAESPSETPGPRPAGPagdepaeSPSETPGPRPAGPAGDEPA 635
Cdd:NF033839 363 PEVKPQPEKPKPEVKPQpetpKPEVKPQPEKPKPEVKPQPEKPKPEVKPQPEKP-------KPEVKPQPEKPKPEVKPQP 435
                        170       180       190       200
                 ....*....|....*....|....*....|....*....|..
gi 33286446  636 ESPSETPGPSPAGPTRDEPAKageaAELQDAEVESSAKSGKP 677
Cdd:NF033839 436 EKPKPEVKPQPEKPKPEVKPQ----PETPKPEVKPQPEKPKP 473
PRK08691 PRK08691
DNA polymerase III subunits gamma and tau; Validated
519-669 1.57e-04

DNA polymerase III subunits gamma and tau; Validated


Pssm-ID: 236333 [Multi-domain]  Cd Length: 709  Bit Score: 45.08  E-value: 1.57e-04
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 33286446  519 SETPGPSPAGPAgdepAESPSETPGPRPAGPAGDEPAESPSETPGPrPAGPAGdEPAESPSETPGPspagPTRDEPaesp 598
Cdd:PRK08691 375 TELQSPSAQTAE----KETAAKKPQPRPEAETAQTPVQTASAAAMP-SEGKTA-GPVSNQENNDVP----PWEDAP---- 440
                         90       100       110       120       130       140       150
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 33286446  599 SETPGPRPAGPAGDEPAESPSETPGPRPAGPAGDEPAE-----SPSETPGPSPAGPT-RDEPAKAGEAAELQDAEVE 669
Cdd:PRK08691 441 DEAQTAAGTAQTSAKSIQTASEAETPPENQVSKNKAADnetdaPLSEVPSENPIQATpNDEAVETETFAHEAPAEPF 517
PRK12373 PRK12373
NADH-quinone oxidoreductase subunit E;
512-629 1.80e-04

NADH-quinone oxidoreductase subunit E;


Pssm-ID: 237082 [Multi-domain]  Cd Length: 400  Bit Score: 44.41  E-value: 1.80e-04
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 33286446  512 EGTPGSPSETPGPSPAGPAGDEPAESPSETPGPRPAgpagdepaespSETPGPRPAGPAgdEPAESPSETPGPSPAGPTR 591
Cdd:PRK12373 224 DGTEVPLLAPWQGDAAPVPPSEAARPKSADAETNAA-----------LKTPATAPKAAA--KNAKAPEAQPVSGTAAAEP 290
                         90       100       110
                 ....*....|....*....|....*....|....*...
gi 33286446  592 DEPAESPSETPGPRPAGPAGDEPAESpsetpgPRPAGP 629
Cdd:PRK12373 291 APKEAAKAAAAAAKPALEDKPRPLGI------ARPGGA 322
PHA03264 PHA03264
envelope glycoprotein D; Provisional
566-654 1.96e-04

envelope glycoprotein D; Provisional


Pssm-ID: 223029 [Multi-domain]  Cd Length: 416  Bit Score: 44.23  E-value: 1.96e-04
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 33286446  566 PAGPAGDEPAESPSETPGPSPAGPTRDEPaeSPSETPGPRPAGPAGDEPAESPsetPGPRPAGPAGDEPAESpseTPGPS 645
Cdd:PHA03264 255 PPYFEESKGYEPPPAPSGGSPAPPGDDRP--EAKPEPGPVEDGAPGRETGGEG---EGPEPAGRDGAAGGEP---KPGPP 326

                 ....*....
gi 33286446  646 PAGPTRDEP 654
Cdd:PHA03264 327 RPAPDADRP 335
SAV_2336_NTERM NF041121
SAV_2336 family N-terminal domain; This HMM describes an N-terminal domain shared by SAV_2336 ...
575-666 2.03e-04

SAV_2336 family N-terminal domain; This HMM describes an N-terminal domain shared by SAV_2336 (BAC70047.1) whose C-terminal region suggests restriction enzyme activity (PMID: 18456708), and with other proteins with unrelated C-terminal regions. A member protein was also identified in a kanamycin biosynthetic gene cluster (PMID:16766657), while N-terminal regions of two other member proteins were named Trypco1 in a bioinformatic study (PMID:32101166) of predicted bacterial conflict systems.


Pssm-ID: 469044 [Multi-domain]  Cd Length: 473  Bit Score: 44.22  E-value: 2.03e-04
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 33286446  575 AESPSETPGPSPAGPTRDEPAESPSETPGPRPAGPAGDEPAESPSETPGPRPAGPAGDepaesPSETPGPSPAGPTRDEP 654
Cdd:NF041121  16 GRAAAPPSPEGPAPTAASQPATPPPPAAPPSPPGDPPEPPAPEPAPLPAPYPGSLAPP-----PPPPPGPAGAAPGAALP 90
                         90
                 ....*....|..
gi 33286446  655 AKAGEAAELQDA 666
Cdd:NF041121  91 VRVPAPPALPNP 102
SepH NF040712
septation protein SepH; Septation protein H (SepH) was firstly characterized in Streptomyces ...
486-633 2.46e-04

septation protein SepH; Septation protein H (SepH) was firstly characterized in Streptomyces venezuelae, and homologs were identified in Mycobacterium smegmatis. SepH contains a N-terminal DUF3071 domain and a conserved C-terminal region. It binds directly to cell division protein FtsZ to stimulate the assembly of FtsZ protofilaments.


Pssm-ID: 468676 [Multi-domain]  Cd Length: 346  Bit Score: 43.99  E-value: 2.46e-04
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 33286446  486 APSGHPKAGHSENGVEEDTEGRTGpkEGTPGSPSET-PGPSPAGPAGDEPAESPSETPGPRPAGPAGDEPAESPSETPGP 564
Cdd:NF040712 200 ATVPRLAREPADARPEEVEPAPAA--EGAPATDSDPaEAGTPDDLASARRRRAGVEQPEDEPVGPGAAPAAEPDEATRDA 277
                         90       100       110       120       130       140
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 33286446  565 RPAGPAGDEPAESPSETPGPSPAGPtrdEPAESPSETPGPRPAgpagdEPAESPSETPGPRPAGPAGDE 633
Cdd:NF040712 278 GEPPAPGAAETPEAAEPPAPAPAAP---AAPAAPEAEEPARPE-----PPPAPKPKRRRRRASVPSWDD 338
PRK14951 PRK14951
DNA polymerase III subunits gamma and tau; Provisional
565-670 2.60e-04

DNA polymerase III subunits gamma and tau; Provisional


Pssm-ID: 237865 [Multi-domain]  Cd Length: 618  Bit Score: 44.32  E-value: 2.60e-04
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 33286446  565 RPAGpAGDEPAESPSETPGPSPAGPTRDEPAESPSETPGPRPAGPAGDEPAESPSETPGPRPAGPAGDEPAESPsETPGP 644
Cdd:PRK14951 365 KPAA-AAEAAAPAEKKTPARPEAAAPAAAPVAQAAAAPAPAAAPAAAASAPAAPPAAAPPAPVAAPAAAAPAAA-PAAAP 442
                         90       100
                 ....*....|....*....|....*.
gi 33286446  645 SPAGPTRDEPAKAGEAAELQDAEVES 670
Cdd:PRK14951 443 AAVALAPAPPAQAAPETVAIPVRVAP 468
PRK14951 PRK14951
DNA polymerase III subunits gamma and tau; Provisional
545-667 2.77e-04

DNA polymerase III subunits gamma and tau; Provisional


Pssm-ID: 237865 [Multi-domain]  Cd Length: 618  Bit Score: 43.93  E-value: 2.77e-04
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 33286446  545 RPAGpAGDEPAESPSETPGPRPAGPAGDEPAESPSETPGPSPAGPTRDEPAESPsetpgprpagPAGDEPAES------- 617
Cdd:PRK14951 365 KPAA-AAEAAAPAEKKTPARPEAAAPAAAPVAQAAAAPAPAAAPAAAASAPAAP----------PAAAPPAPVaapaaaa 433
                         90       100       110       120       130       140
                 ....*....|....*....|....*....|....*....|....*....|....*....|
gi 33286446  618 --PSETPGPRPAGPAGDEPAESPSET--------PGPSPAGPtRDEPAKAGEAAELQDAE 667
Cdd:PRK14951 434 paAAPAAAPAAVALAPAPPAQAAPETvaipvrvaPEPAVASA-APAPAAAPAAARLTPTE 492
PHA03269 PHA03269
envelope glycoprotein C; Provisional
518-624 3.17e-04

envelope glycoprotein C; Provisional


Pssm-ID: 165527 [Multi-domain]  Cd Length: 566  Bit Score: 43.95  E-value: 3.17e-04
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 33286446  518 PSETPGPSPAGPAGDEPAESPSETPG--PRPAGPAGDEPAESPSETPGPRPAGPAGDEPAESPSETPGPSPagptrdEPA 595
Cdd:PHA03269  40 PDPAPAPHQAASRAPDPAVAPTSAASrkPDLAQAPTPAASEKFDPAPAPHQAASRAPDPAVAPQLAAAPKP------DAA 113
                         90       100
                 ....*....|....*....|....*....
gi 33286446  596 ESPSETPGPRPAgpAGDEPAESPSETPGP 624
Cdd:PHA03269 114 EAFTSAAQAHEA--PADAGTSAASKKPDP 140
PRK12373 PRK12373
NADH-quinone oxidoreductase subunit E;
527-636 3.22e-04

NADH-quinone oxidoreductase subunit E;


Pssm-ID: 237082 [Multi-domain]  Cd Length: 400  Bit Score: 43.64  E-value: 3.22e-04
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 33286446  527 AGPAGDePAESPSETPGPRPAGPAGDEPAESPSETPGPRPAGPAGDEPAESPSETPGPsPAGPTRDEPAESPSETPGPRP 606
Cdd:PRK12373 213 AEDIGD-TVKRIDGTEVPLLAPWQGDAAPVPPSEAARPKSADAETNAALKTPATAPKA-AAKNAKAPEAQPVSGTAAAEP 290
                         90       100       110
                 ....*....|....*....|....*....|...
gi 33286446  607 AGP---AGDEPAESPSETPGPRPAGPAGDEPAE 636
Cdd:PRK12373 291 APKeaaKAAAAAAKPALEDKPRPLGIARPGGAD 323
PRK14950 PRK14950
DNA polymerase III subunits gamma and tau; Provisional
522-620 3.58e-04

DNA polymerase III subunits gamma and tau; Provisional


Pssm-ID: 237864 [Multi-domain]  Cd Length: 585  Bit Score: 43.64  E-value: 3.58e-04
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 33286446  522 PGPSPAGPAgdEPAESPSeTPGPRPAgpagdepaeSPSETPGPRPAGPAGDEPAESPSETPGPSPAGPTRDEPAESPSET 601
Cdd:PRK14950 364 PAPQPAKPT--AAAPSPV-RPTPAPS---------TRPKAAAAANIPPKEPVRETATPPPVPPRPVAPPVPHTPESAPKL 431
                         90       100
                 ....*....|....*....|..
gi 33286446  602 PG---PRPAGPAGDEPAESPSE 620
Cdd:PRK14950 432 TRaaiPVDEKPKYTPPAPPKEE 453
PRK12373 PRK12373
NADH-quinone oxidoreductase subunit E;
511-609 5.43e-04

NADH-quinone oxidoreductase subunit E;


Pssm-ID: 237082 [Multi-domain]  Cd Length: 400  Bit Score: 42.87  E-value: 5.43e-04
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 33286446  511 KEGTPGSPSETPGPSPAGPAGDePAEspsETPGPRPAGPAgdEPAESPSETPgprPAGPAGDEPAESPSETPGPSPAGPT 590
Cdd:PRK12373 236 GDAAPVPPSEAARPKSADAETN-AAL---KTPATAPKAAA--KNAKAPEAQP---VSGTAAAEPAPKEAAKAAAAAAKPA 306
                         90       100
                 ....*....|....*....|..
gi 33286446  591 ---RDEPAESpsetpgPRPAGP 609
Cdd:PRK12373 307 ledKPRPLGI------ARPGGA 322
PRK01297 PRK01297
ATP-dependent RNA helicase RhlB; Provisional
595-669 5.46e-04

ATP-dependent RNA helicase RhlB; Provisional


Pssm-ID: 234938 [Multi-domain]  Cd Length: 475  Bit Score: 42.98  E-value: 5.46e-04
                         10        20        30        40        50        60        70
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 33286446  595 AESPSETPGPRPAGPAGDEPAESPSETPGPRPAGPAGDEPAESPsetpgPSPAGPTRDEPAKAGEAAELQDAEVE 669
Cdd:PRK01297  12 GEAEQPAPAPPSPAAAPAPPPPAKTAAPATKAAAPAAAAPRAEK-----PKKDKPRRERKPKPASLWKLEDFVVE 81
PRK14965 PRK14965
DNA polymerase III subunits gamma and tau; Provisional
594-669 5.68e-04

DNA polymerase III subunits gamma and tau; Provisional


Pssm-ID: 237871 [Multi-domain]  Cd Length: 576  Bit Score: 43.19  E-value: 5.68e-04
                         10        20        30        40        50        60        70
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 33286446  594 PAESPSETPGPRPAGPAgdePAESPSETPGPRPAGPAGDEPAESPSETPGPSPAGPTRDePAKAGEAAELQDAEVE 669
Cdd:PRK14965 384 PPSAAWGAPTPAAPAAP---PPAAAPPVPPAAPARPAAARPAPAPAPPAAAAPPARSAD-PAAAASAGDRWRAFVA 455
PLN03209 PLN03209
translocon at the inner envelope of chloroplast subunit 62; Provisional
518-677 5.73e-04

translocon at the inner envelope of chloroplast subunit 62; Provisional


Pssm-ID: 178748 [Multi-domain]  Cd Length: 576  Bit Score: 42.99  E-value: 5.73e-04
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 33286446  518 PSETPGPsPAGPAGDEPAESPSETPGPR-PAGPAGDEPAESPSETPGPRPAGPAGDE--PAESPSET-PGPSPAGPTRDE 593
Cdd:PLN03209 324 PSQRVPP-KESDAADGPKPVPTKPVTPEaPSPPIEEEPPQPKAVVPRPLSPYTAYEDlkPPTSPIPTpPSSSPASSKSVD 402
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 33286446  594 PAESPSE-TPGPRPAGPAG-DEPAESPSETPGPRPAGP----AGDEPAESPSETPgPSPAGPTRDEPAKAGEAAELQDAE 667
Cdd:PLN03209 403 AVAKPAEpDVVPSPGSASNvPEVEPAQVEAKKTRPLSPyaryEDLKPPTSPSPTA-PTGVSPSVSSTSSVPAVPDTAPAT 481
                        170
                 ....*....|
gi 33286446  668 VESSAKSGKP 677
Cdd:PLN03209 482 AATDAAAPPP 491
Herpes_BLLF1 pfam05109
Herpes virus major outer envelope glycoprotein (BLLF1); This family consists of the BLLF1 ...
468-639 6.69e-04

Herpes virus major outer envelope glycoprotein (BLLF1); This family consists of the BLLF1 viral late glycoprotein, also termed gp350/220. It is the most abundantly expressed glycoprotein in the viral envelope of the Herpesviruses and is the major antigen responsible for stimulating the production of neutralising antibodies in vivo.


Pssm-ID: 282904 [Multi-domain]  Cd Length: 886  Bit Score: 42.98  E-value: 6.69e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 33286446   468 SAAVASGGAQTLALAGSPAPSGH--------PKAGHSENGVEEdtegrTGPKEGTPGSPSETPGPSPAGPAgdePAESps 539
Cdd:pfam05109 459 TAPASTGPTVSTADVTSPTPAGTtsgaspvtPSPSPRDNGTES-----KAPDMTSPTSAVTTPTPNATSPT---PAVT-- 528
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 33286446   540 eTPGPRPAGPA-GDEPAESPSETPGPRPAGPAgdePAESpseTPGPSPAGPTRDEPA-ESPSETPGPRPAGPAGDEP--- 614
Cdd:pfam05109 529 -TPTPNATSPTlGKTSPTSAVTTPTPNATSPT---PAVT---TPTPNATIPTLGKTSpTSAVTTPTPNATSPTVGETspq 601
                         170       180
                  ....*....|....*....|....*
gi 33286446   615 AESPSETPGPRPAGPAGDEPAESPS 639
Cdd:pfam05109 602 ANTTNHTLGGTSSTPVVTSPPKNAT 626
PRK10263 PRK10263
DNA translocase FtsK; Provisional
468-659 7.61e-04

DNA translocase FtsK; Provisional


Pssm-ID: 236669 [Multi-domain]  Cd Length: 1355  Bit Score: 42.76  E-value: 7.61e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 33286446   468 SAAVASGGAQTLALAGSPAPSGHPKAGHSENGVEEDTEGRTGPKEGTPgSPSETPGPSpagpagdepaespSETPGPRPA 547
Cdd:PRK10263  322 VAAAATTATQSWAAPVEPVTQTPPVASVDVPPAQPTVAWQPVPGPQTG-EPVIAPAPE-------------GYPQQSQYA 387
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 33286446   548 GPAgdEPAESPSETPGPrPAGPAGDEPAESPSETPGPSPAGPTRDEPAESPSETPGPRPAGPAGDEPAESP-SETPGPRP 626
Cdd:PRK10263  388 QPA--VQYNEPLQQPVQ-PQQPYYAPAAEQPAQQPYYAPAPEQPAQQPYYAPAPEQPVAGNAWQAEEQQSTfAPQSTYQT 464
                         170       180       190
                  ....*....|....*....|....*....|...
gi 33286446   627 AGPAGDEPAESPSETPGPSPAGPTRDEPAKAGE 659
Cdd:PRK10263  465 EQTYQQPAAQEPLYQQPQPVEQQPVVEPEPVVE 497
PTZ00441 PTZ00441
sporozoite surface protein 2 (SSP2); Provisional
493-654 7.87e-04

sporozoite surface protein 2 (SSP2); Provisional


Pssm-ID: 240420 [Multi-domain]  Cd Length: 576  Bit Score: 42.64  E-value: 7.87e-04
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 33286446  493 AGHSENGVEEDTEGRTGPKEgtpgSPSETPGPSPAGPAGDEPAESPSETPGPRP-----AGPAGDEPAESPSETPGPRPA 567
Cdd:PTZ00441 267 EGCTTHMVEECEEEECPVEP----EPLPVPAPVPPTPEDDNPRPTDDEFAVPNFnegldVPDNPQDPVPPPNEGKDGNPN 342
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 33286446  568 G-----PAGDE-PAESPSETPGPSPAGPTRDEPAESPSETPGP-RPAGPAGDEPAESPSETPGPRPAGPAGDEPAESPSE 640
Cdd:PTZ00441 343 EenlfpPGDDEvPDESNVPPNPPNVPGGSNSEFSSDVENPPNPpNPDIPEQEPNIPEDSNKEVPEDVPMEPEDDRDNNFN 422
                        170
                 ....*....|....*
gi 33286446  641 TP-GPSPAGPTRDEP 654
Cdd:PTZ00441 423 EPkKPENKGDGQNEP 437
CLEC16A_C pfam19439
CLEC16A C-terminal; This is the C-terminal domain of C-type lectin domain family 16, member A ...
554-647 8.05e-04

CLEC16A C-terminal; This is the C-terminal domain of C-type lectin domain family 16, member A (CLEC16A, the Drosophila orthologue Ema and GOP-1 in C. elegans), an evolutionarily conserved endosomal membrane protein required for trafficking of fluid-phase and receptor-mediated endocytic cargos. It is required for mitophagy, autophagy and endosome maturation. This protein has been identified as a susceptibility gene for autoimmune diseases like type 1 diabetes, multiple sclerosis and adrenal dysfunction. This domain is also present in GFS9/TT9 (TRANSPARENT TESTA 9) a protein from Arabidopsis required for vacuolar development through membrane fusion at vacuoles and for membrane trafficking machinery and accumulation of flavonoids in the seed coat.


Pssm-ID: 466083  Cd Length: 762  Bit Score: 42.56  E-value: 8.05e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 33286446   554 PAESPSETPGPRPAGPAGDEPAESPSETPGPSpagptrdePAESPSETPGPRPAGPAGDEPAESPSETPGPRPAGPAGDE 633
Cdd:pfam19439 645 PLSSPSPPSSSSGSGSTGRCDSVTASSTSTPS--------PSDDGSTPEQPQLPDELAFLDSTPAVSKPGKSSASSETEP 716
                          90
                  ....*....|....
gi 33286446   634 PAESPSETPGPSPA 647
Cdd:pfam19439 717 AALAPSLTPAPQPT 730
PRK11633 PRK11633
cell division protein DedD; Provisional
552-660 8.20e-04

cell division protein DedD; Provisional


Pssm-ID: 236940 [Multi-domain]  Cd Length: 226  Bit Score: 41.53  E-value: 8.20e-04
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 33286446  552 DEPAESPSETPgprpagPAGDEPAESPSETPGPSPAGPTRDEPAESPSETPGPRPAGPagdePAESPSETPGPRPAGPAG 631
Cdd:PRK11633  51 DEPDMMPAATQ------ALPTQPPEGAAEAVRAGDAAAPSLDPATVAPPNTPVEPEPA----PVEPPKPKPVEKPKPKPK 120
                         90       100
                 ....*....|....*....|....*....
gi 33286446  632 DEPAESPSETPGPSPAGPTRDEPAKAGEA 660
Cdd:PRK11633 121 PQQKVEAPPAPKPEPKPVVEEKAAPTGKA 149
KREPA2 cd23959
Kinetoplastid RNA Editing Protein A2 (KREPA2); The KREPA2 (TbMP63) protein is a component of ...
532-666 8.23e-04

Kinetoplastid RNA Editing Protein A2 (KREPA2); The KREPA2 (TbMP63) protein is a component of the parasitic protozoan's KREPA RNA editing catalytic complex (RECC). Kinetoplastid RNA editing (KRE) proteins occur as pairs or sets of related proteins in multiple complexes. KREPA complex is composed of six components (KREPA1-6), which share a conserved C-terminal region containing an oligonucleotide-binding (OB)-fold-like domain. KREPAs are responsible for the site-specific insertion and deletion of U nucleotides in the kinetoplastid mitochondria pre-messenger RNA. Apart from the conserved C-terminal OB-fold domain, KREPA1, KREPA2, and KREPA3 contain two conserved C2H2 zinc-finger domains. KREPA2 and kinetoplastid RNA editing ligase 1 (KREL1) are specific for ligation post-U-deletion and are paralogous to KREL2 and KREPA1 that are specific for ligation post-U-insertion. KREPA2, is critical for RECC stability and KREL1 integration into the complex.


Pssm-ID: 467780 [Multi-domain]  Cd Length: 424  Bit Score: 42.16  E-value: 8.23e-04
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 33286446 532 DEPAESPSETPGP-RPAGPAGDEPAESPSETPGPRPAGPAGD--EPAESPSETPG--------PSPAGPTRDEPAE---- 596
Cdd:cd23959  97 DAFAMAPDESLGPfRAARVPNPFSASSSTQRETHKTAQVAPPkaEPQTAPVTPFGqlpmfgqhPPPAKPLPAAAAAqqss 176
                        90       100       110       120       130       140       150
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 33286446 597 -SPSETPGPRPAGPAGDEPAESPSETPGPRPAGPAGDEPAESPSETPGPSPAGPTRDEPAKAGEAAELQDA 666
Cdd:cd23959 177 aSPGEVASPFASGTVSASPFATATDTAPSSGAPDGFPAEASAPSPFAAPASAASFPAAPVANGEAATPTHA 247
PRK14971 PRK14971
DNA polymerase III subunit gamma/tau;
502-615 9.26e-04

DNA polymerase III subunit gamma/tau;


Pssm-ID: 237874 [Multi-domain]  Cd Length: 614  Bit Score: 42.46  E-value: 9.26e-04
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 33286446  502 EDTEGRTGPKEgtPGSPSETpGPSPAGPAGDEPAESPSETPGPRPAGPAGDEPAESPSETPGPRPAGPAGDEPAESPSET 581
Cdd:PRK14971 367 DDASGGRGPKQ--HIKPVFT-QPAAAPQPSAAAAASPSPSQSSAAAQPSAPQSATQPAGTPPTVSVDPPAAVPVNPPSTA 443
                         90       100       110       120
                 ....*....|....*....|....*....|....*....|....
gi 33286446  582 P---GPSPAGPTRDEP-AESPSETPG------PRPAGPAGDEPA 615
Cdd:PRK14971 444 PqavRPAQFKEEKKIPvSKVSSLGPStlrpiqEKAEQATGNIKE 487
PBP1 COG5180
PAB1-binding protein, interacts with poly(A)-binding protein [RNA processing and modification]; ...
351-677 9.33e-04

PAB1-binding protein, interacts with poly(A)-binding protein [RNA processing and modification];


Pssm-ID: 444064 [Multi-domain]  Cd Length: 548  Bit Score: 42.36  E-value: 9.33e-04
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 33286446 351 EPQDAGPLERSQGDEAGGHGEDRPEPLSPKESKKRKLELSRREQPPTEPGPQSASEVEKiaLNLEGCALSQGSLRTGTQE 430
Cdd:COG5180 140 EATSASAGVALAAALLQRSDPILAKDPDGDSASTLPPPAEKLDKVLTEPRDALKDSPEK--LDRPKVEVKDEAQEEPPDL 217
                        90       100       110       120       130       140       150       160
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 33286446 431 VGGQD---PGEAVQPCRQPLGARVADKVRKRRKVDEGAGDSAAVASGGAQTLALAGSPAPSGHPKAGHSENGVEEDTEGR 507
Cdd:COG5180 218 TGGADhprPEAASSPKVDPPSTSEARSRPATVDAQPEMRPPADAKERRRAAIGDTPAAEPPGLPVLEAGSEPQSDAPEAE 297
                       170       180       190       200       210       220       230       240
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 33286446 508 TGPKEGTPGSPSETPGPSPAGPAGD--EPAESPSETPGPRPAG--PAGDEPAESPSETPGPRPAGPAGDEPAESP---SE 580
Cdd:COG5180 298 TARPIDVKGVASAPPATRPVRPPGGarDPGTPRPGQPTERPAGvpEAASDAGQPPSAYPPAEEAVPGKPLEQGAPrpgSS 377
                       250       260       270       280       290       300       310       320
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 33286446 581 TPGPSPAGPTRDEPAESPSETPGPRPAGPAGDE-PAESPSETPGPRPAGPAGDEPAESPSETPGPSPAGPTRDEP---AK 656
Cdd:COG5180 378 GGDGAPFQPPNGAPQPGLGRRGAPGPPMGAGDLvQAALDGGGRETASLGGAAGGAGQGPKADFVPGDAESVSGPAglaDQ 457
                       330       340
                ....*....|....*....|.
gi 33286446 657 AGEAAELQDAEVESSAKSGKP 677
Cdd:COG5180 458 AGAAASTAMADFVAPVTDATP 478
PRK14950 PRK14950
DNA polymerase III subunits gamma and tau; Provisional
542-668 9.36e-04

DNA polymerase III subunits gamma and tau; Provisional


Pssm-ID: 237864 [Multi-domain]  Cd Length: 585  Bit Score: 42.49  E-value: 9.36e-04
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 33286446  542 PGPRPAGPAgdEPAESPSeTPGPRPAGPAGDEPAESPSETPgPSPAGPTRDEPAESPSETPGPRPagpagdepaeSPSET 621
Cdd:PRK14950 364 PAPQPAKPT--AAAPSPV-RPTPAPSTRPKAAAAANIPPKE-PVRETATPPPVPPRPVAPPVPHT----------PESAP 429
                         90       100       110       120
                 ....*....|....*....|....*....|....*....|....*..
gi 33286446  622 PGPRPAGPAGDEPAESPsetpgpsPAGPTRDEPAKAGEAAELQDAEV 668
Cdd:PRK14950 430 KLTRAAIPVDEKPKYTP-------PAPPKEEEKALIADGDVLEQLEA 469
PRK14971 PRK14971
DNA polymerase III subunit gamma/tau;
536-674 9.42e-04

DNA polymerase III subunit gamma/tau;


Pssm-ID: 237874 [Multi-domain]  Cd Length: 614  Bit Score: 42.46  E-value: 9.42e-04
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 33286446  536 ESPSETPGPRPAGPAGDEPAespsetPGPRPAGPAGDEPAESPSETPGPSPAGPtrdePAESPSETPGPRPAGPAGDEPA 615
Cdd:PRK14971 368 DASGGRGPKQHIKPVFTQPA------AAPQPSAAAAASPSPSQSSAAAQPSAPQ----SATQPAGTPPTVSVDPPAAVPV 437
                         90       100       110       120       130       140
                 ....*....|....*....|....*....|....*....|....*....|....*....|.
gi 33286446  616 ESPSETPGPRPAGPAGDEPAESPSETP--GPSPAGPTRdePAKAGEAAELQDAEVESSAKS 674
Cdd:PRK14971 438 NPPSTAPQAVRPAQFKEEKKIPVSKVSslGPSTLRPIQ--EKAEQATGNIKEAPTGTQKEI 496
PRK12373 PRK12373
NADH-quinone oxidoreductase subunit E;
518-665 9.55e-04

NADH-quinone oxidoreductase subunit E;


Pssm-ID: 237082 [Multi-domain]  Cd Length: 400  Bit Score: 42.10  E-value: 9.55e-04
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 33286446  518 PSETPGPSpAGPAGDEPAESPSE--TPGPRPAGPAGDEPAESPSET--------------PGPRPAGPAGDEPAESPSET 581
Cdd:PRK12373 175 PVVKPGPQ-IGRYASEPAGGLTSltEEAGKARYNASKALAEDIGDTvkridgtevpllapWQGDAAPVPPSEAARPKSAD 253
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 33286446  582 PGPSPAgptrdepaespSETPGPRPAGPAgdEPAESPSETPgprPAGPAGDEPAESPSETPGPSPAGPT---RDEPAKAG 658
Cdd:PRK12373 254 AETNAA-----------LKTPATAPKAAA--KNAKAPEAQP---VSGTAAAEPAPKEAAKAAAAAAKPAledKPRPLGIA 317

                 ....*..
gi 33286446  659 EAAELQD 665
Cdd:PRK12373 318 RPGGADD 324
PRK11633 PRK11633
cell division protein DedD; Provisional
510-630 1.03e-03

cell division protein DedD; Provisional


Pssm-ID: 236940 [Multi-domain]  Cd Length: 226  Bit Score: 41.14  E-value: 1.03e-03
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 33286446  510 PKEGTPGSPSETPGPSPAGPAgdEPAESPSETPGPRPAGPAGDEPAESPSETPGPRPAGPagdepaesPSETPGPSPAGP 589
Cdd:PRK11633  45 PKPGDRDEPDMMPAATQALPT--QPPEGAAEAVRAGDAAAPSLDPATVAPPNTPVEPEPA--------PVEPPKPKPVEK 114
                         90       100       110       120
                 ....*....|....*....|....*....|....*....|.
gi 33286446  590 TRDEPAESPSETPGPRPAgpagdePAESPSETPGPRPAGPA 630
Cdd:PRK11633 115 PKPKPKPQQKVEAPPAPK------PEPKPVVEEKAAPTGKA 149
PTZ00429 PTZ00429
beta-adaptin; Provisional
483-629 1.06e-03

beta-adaptin; Provisional


Pssm-ID: 240415 [Multi-domain]  Cd Length: 746  Bit Score: 42.23  E-value: 1.06e-03
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 33286446  483 GSPAPSGHPKAGH-SENGVEEDTEgrtgPKEGTPGSPSETPGPSPAGPAgdePAESPSETPGPRPAGPAGDEPAESPSET 561
Cdd:PTZ00429 591 ARPYQSFLPPYGLaDVELDEEDTE----DDDAVELPSTPSMGTQDGSPA---PSAAPAGYDIFEFAGDGTGAPHPVASGS 663
                         90       100       110       120       130       140       150
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 33286446  562 PGPRPAGPAGDEPAESPSETPGPSPA---GPTRDEPAESPseTPGPRPAGPAGDEPAESPSETPGPRPAGP 629
Cdd:PTZ00429 664 NGAQHADPLGDLFSGLPSTVGASSPAfqaASGSQAPASPP--TAASAIEDLFANGMGSGSQTVPLPISAAP 732
PHA03325 PHA03325
nuclear-egress-membrane-like protein; Provisional
484-644 1.20e-03

nuclear-egress-membrane-like protein; Provisional


Pssm-ID: 223044  Cd Length: 418  Bit Score: 41.79  E-value: 1.20e-03
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 33286446  484 SPAPSGHPKAGHSENGVEEDTEGRTGPKEGTPGSPSETPGPSPagpagDEPAESPSETPGPRPAGPAGDEPAESPSETPG 563
Cdd:PHA03325 266 SSLPTSAPKRRSRRAGAMRAAAGETADLADDDGSEHSDPEPLP-----ASLPPPPVRRPRVKHPEAGKEEPDGARNAEAK 340
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 33286446  564 PRPAGPAGDEPAESPSETPGPSPAGPTRDEPAESPSETPGPRPAGPAGDEPaespsetpgPRPAGPAGDEPAESPSETPG 643
Cdd:PHA03325 341 EPAQPATSTSSKGSSSAQNKDSGSTGPGSSLAAASSFLEDDDFGSPPLDLT---------TSLRHMPSPSVTSAPEPPSI 411

                 .
gi 33286446  644 P 644
Cdd:PHA03325 412 P 412
SPS1 COG0515
Serine/threonine protein kinase [Signal transduction mechanisms];
401-631 1.24e-03

Serine/threonine protein kinase [Signal transduction mechanisms];


Pssm-ID: 440281 [Multi-domain]  Cd Length: 482  Bit Score: 41.92  E-value: 1.24e-03
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 33286446 401 PQSASEVekiALNLEGCALSQGSLRTGTQEVGGQDPGEAVQPCRQPLGARVADKVRKRRKVDEGAGDSAAVASGGAQTLA 480
Cdd:COG0515 255 YQSAAEL---AAALRAVLRSLAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAPAAAAAAAA 331
                        90       100       110       120       130       140       150       160
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 33286446 481 LAGSPAPSGHPKAGHSENGVEEDTEGRTGPKEGTPGSPSETPGPSPAGPAGDEPAESPSETPGPRPAGPAGDEPAESPSE 560
Cdd:COG0515 332 AAAALAAAAAAAAAAAAAALLAAAAALAAAAAAAAAAAAAAAAAAAAAAAAAALAAAAAAAAAAAAAALAAAAAAAAAAA 411
                       170       180       190       200       210       220       230
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 33286446 561 TPGPRPAGPAGDEPAESPSETPGPSPAGPTRDEPAESPSETPGPRPAGPAGDEPAESPSETPGPRPAGPAG 631
Cdd:COG0515 412 AAAAAAAALAAAAAAAAAAAAAAAAAAAAAARLLAAAAAAAAAAAAAPLLAALLAAAALAAAAAAAALALA 482
PRK14965 PRK14965
DNA polymerase III subunits gamma and tau; Provisional
534-605 1.30e-03

DNA polymerase III subunits gamma and tau; Provisional


Pssm-ID: 237871 [Multi-domain]  Cd Length: 576  Bit Score: 42.04  E-value: 1.30e-03
                         10        20        30        40        50        60        70
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 33286446  534 PAESPSETPGPRPAGPAgdePAESPSETPGPRPAGPAGDEPAESPsetPGPSPAGPTRDEPAESPSETPGPR 605
Cdd:PRK14965 384 PPSAAWGAPTPAAPAAP---PPAAAPPVPPAAPARPAAARPAPAP---APPAAAAPPARSADPAAAASAGDR 449
PHA03201 PHA03201
uracil DNA glycosylase; Provisional
555-638 1.35e-03

uracil DNA glycosylase; Provisional


Pssm-ID: 165468  Cd Length: 318  Bit Score: 41.42  E-value: 1.35e-03
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 33286446  555 AESPSETPGPRPAGPAGDEPAE---SPSETPgPSPAGPTRDEPAESPSETPGPRpAGPAGDEPAESPSETPGPRPAGPAG 631
Cdd:PHA03201   4 ARSRSPSPPRRPSPPRPTPPRSpdaSPEETP-PSPPGPGAEPPPGRAAGPAAPR-RRPRGCPAGVTFSSSAPPRPPLGLD 81

                 ....*..
gi 33286446  632 DEPAESP 638
Cdd:PHA03201  82 DAPAATP 88
PHA03307 PHA03307
transcriptional regulator ICP4; Provisional
529-666 1.60e-03

transcriptional regulator ICP4; Provisional


Pssm-ID: 223039 [Multi-domain]  Cd Length: 1352  Bit Score: 41.70  E-value: 1.60e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 33286446   529 PAGDEPAESPSETPGPRPAGPAGDEPAESPSETPGPRPAGPAGDEPAESPsetpGPSPAGPTRDEPAESPSETPGPRPAG 608
Cdd:PHA03307  765 PAKLAEALALLEPAEPQRGAGSSPPVRAEAAFRRPGRLRRSGPAADAASR----TASKRKSRSHTPDGGSESSGPARPPG 840
                          90       100       110       120       130
                  ....*....|....*....|....*....|....*....|....*....|....*...
gi 33286446   609 PAGDEPAESPSETPGPRPAGPAGDEPAESPSETPGPSPAGPTRDEPAKAGEAAELQDA 666
Cdd:PHA03307  841 AAARPPPARSSESSKSKPAAAGGRARGKNGRRRPRPPEPRARPGAAAPPKAAAAAPPA 898
PLN03209 PLN03209
translocon at the inner envelope of chloroplast subunit 62; Provisional
487-649 2.19e-03

translocon at the inner envelope of chloroplast subunit 62; Provisional


Pssm-ID: 178748 [Multi-domain]  Cd Length: 576  Bit Score: 41.07  E-value: 2.19e-03
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 33286446  487 PSGHPKAGHSENGVEEDTEGRTGPKEGTPGS-------PSETPGPSPAGPAGDEPAESPSETPGPRPAGPAGDEPAESPS 559
Cdd:PLN03209 391 PSSSPASSKSVDAVAKPAEPDVVPSPGSASNvpevepaQVEAKKTRPLSPYARYEDLKPPTSPSPTAPTGVSPSVSSTSS 470
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 33286446  560 ETPGPRPAgpagdePAESPSETPGPSPAGPTRDEPAESPSETPGPRPAGPAGDEPAESPSETPGPRPAGPAGDEPA---E 636
Cdd:PLN03209 471 VPAVPDTA------PATAATDAAAPPPANMRPLSPYAVYDDLKPPTSPSPAAPVGKVAPSSTNEVVKVGNSAPPTAladE 544
                        170
                 ....*....|...
gi 33286446  637 SPSETPGPSPAGP 649
Cdd:PLN03209 545 QHHAQPKPRPLSP 557
Herpes_BLLF1 pfam05109
Herpes virus major outer envelope glycoprotein (BLLF1); This family consists of the BLLF1 ...
536-650 2.19e-03

Herpes virus major outer envelope glycoprotein (BLLF1); This family consists of the BLLF1 viral late glycoprotein, also termed gp350/220. It is the most abundantly expressed glycoprotein in the viral envelope of the Herpesviruses and is the major antigen responsible for stimulating the production of neutralising antibodies in vivo.


Pssm-ID: 282904 [Multi-domain]  Cd Length: 886  Bit Score: 41.44  E-value: 2.19e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 33286446   536 ESPSETPGPRPAGPAGDEPAES-PSETPGPRP-AGPAGDEPAESPSETPGPSPAGPTRDEPAESPSetPGPRPAGPAGDE 613
Cdd:pfam05109 426 ESTTTSPTLNTTGFAAPNTTTGlPSSTHVPTNlTAPASTGPTVSTADVTSPTPAGTTSGASPVTPS--PSPRDNGTESKA 503
                          90       100       110       120
                  ....*....|....*....|....*....|....*....|.
gi 33286446   614 P-AESPSE---TPGPRPAGPAgdePAESpseTPGPSPAGPT 650
Cdd:pfam05109 504 PdMTSPTSavtTPTPNATSPT---PAVT---TPTPNATSPT 538
PRK14959 PRK14959
DNA polymerase III subunits gamma and tau; Provisional
521-642 2.21e-03

DNA polymerase III subunits gamma and tau; Provisional


Pssm-ID: 184923 [Multi-domain]  Cd Length: 624  Bit Score: 41.20  E-value: 2.21e-03
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 33286446  521 TPGPSPAGPAGDEPAESPSE-----TPGPRPAGPAGDEPAESPSetpgPRPAGPAGDEPAESpsetpgPSPAGPTRDEPA 595
Cdd:PRK14959 372 RPSGGGASAPSGSAAEGPASggaatIPTPGTQGPQGTAPAAGMT----PSSAAPATPAPSAA------PSPRVPWDDAPP 441
                         90       100       110       120       130
                 ....*....|....*....|....*....|....*....|....*....|...
gi 33286446  596 ESPSETPGPRP------AGPAGDEPAeSPSETPGPRPAGPAGDEPAESPSETP 642
Cdd:PRK14959 442 APPRSGIPPRPaprmpeASPVPGAPD-SVASASDAPPTLGDPSDTAEHTPSGP 493
SAV_2336_NTERM NF041121
SAV_2336 family N-terminal domain; This HMM describes an N-terminal domain shared by SAV_2336 ...
503-591 2.48e-03

SAV_2336 family N-terminal domain; This HMM describes an N-terminal domain shared by SAV_2336 (BAC70047.1) whose C-terminal region suggests restriction enzyme activity (PMID: 18456708), and with other proteins with unrelated C-terminal regions. A member protein was also identified in a kanamycin biosynthetic gene cluster (PMID:16766657), while N-terminal regions of two other member proteins were named Trypco1 in a bioinformatic study (PMID:32101166) of predicted bacterial conflict systems.


Pssm-ID: 469044 [Multi-domain]  Cd Length: 473  Bit Score: 40.76  E-value: 2.48e-03
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 33286446  503 DTEGRTGPKEGTPGSPSETPGPSPAGPAGDEPAESPSETPGPRPAGPAGDEPAESPSeTPGPRPAGPAGDEPAESPSETP 582
Cdd:NF041121  20 APPSPEGPAPTAASQPATPPPPAAPPSPPGDPPEPPAPEPAPLPAPYPGSLAPPPPP-PPGPAGAAPGAALPVRVPAPPA 98

                 ....*....
gi 33286446  583 GPSPAGPTR 591
Cdd:NF041121  99 LPNPLELAR 107
PRK10263 PRK10263
DNA translocase FtsK; Provisional
517-677 2.55e-03

DNA translocase FtsK; Provisional


Pssm-ID: 236669 [Multi-domain]  Cd Length: 1355  Bit Score: 41.22  E-value: 2.55e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 33286446   517 SPSETPGPSPAGPAGDEPAESPS----ETPGPRPAGPAGDEPAESPSETPGPRPAGPAGDEPAESPSEtPGPSPAGPTRD 592
Cdd:PRK10263  335 APVEPVTQTPPVASVDVPPAQPTvawqPVPGPQTGEPVIAPAPEGYPQQSQYAQPAVQYNEPLQQPVQ-PQQPYYAPAAE 413
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 33286446   593 EPAESPSETPGPRPAG----PAGDEPAESPSETPGPRPAGPAGDEPAESPSETPGPSPAGPtrDEPAKAGEAAELQDA-E 667
Cdd:PRK10263  414 QPAQQPYYAPAPEQPAqqpyYAPAPEQPVAGNAWQAEEQQSTFAPQSTYQTEQTYQQPAAQ--EPLYQQPQPVEQQPVvE 491
                         170
                  ....*....|
gi 33286446   668 VESSAKSGKP 677
Cdd:PRK10263  492 PEPVVEETKP 501
KLF14_N cd21576
N-terminal domain of Kruppel-like factor 14; Kruppel-like factor 14 (KLF14; also known as ...
522-650 2.58e-03

N-terminal domain of Kruppel-like factor 14; Kruppel-like factor 14 (KLF14; also known as Krueppel-like factor 14 or basic transcription element-binding protein 5/BTEB5) is a protein that in humans is encoded by the KLF14 gene. KLF14 regulates the transcription of various genes, including TGFbetaRII (the type II receptor for TGFbeta). KLF14 is expressed in many tissues, lacks introns, and is subject to parent-specific expression. It also appears to be a master regulator of gene expression in adipose tissue. KLF14 is associated with coronary artery disease, hypercholesterolemia, and type 2 diabetes. KLF9, KLF10, KLF11, KLF13, KLF14, and KLF16 share a conserved alpha-helical motif AA/VXXL that mediates their binding to Sin3A and their activities as transcriptional repressors. KLF14 belongs to a family of proteins, called the Specificity Protein (SP)/KLF family, characterized by a C-terminal DNA-binding domain of 81 amino acids consisting of three Kruppel-like C2H2 zinc fingers. These factors bind to a loose consensus motif, namely NNRCRCCYY (where N is any nucleotide; R is A/G, and Y is C/T), such as the recurring motifs in GC and GT boxes (5'-GGGGCGGGG-3' and 5-GGTGTGGGG-3') that are present in promoters and more distal regulatory elements of mammalian genes. Members of the KLF family can act as activators or repressors of transcription depending on cell and promoter context. KLFs regulate various cellular functions, such as proliferation, differentiation, and apoptosis, as well as the development and homeostasis of several types of tissue. In addition to the C-terminal DNA-binding domain, each KLF also has a unique N-terminal activation/repression domain that confers specificity and allows it to bind specifically to a certain partner, leading to distinct activities in vivo. This model represents the N-terminal domain of KLF14.


Pssm-ID: 409238 [Multi-domain]  Cd Length: 195  Bit Score: 39.80  E-value: 2.58e-03
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 33286446 522 PGPSPAGP-AGDEPAESPSET--PGPRPAGPAGDEPAESPSETPGPRPA---------------GPAGDEPAESPSETPG 583
Cdd:cd21576  29 PDPEGAGGaAGSEVGAAPPESalPGPGPPGPAWVPPLLQVPAPSPGAGGaaphllaasvladlrGGAGEGSREDSGEAPR 108
                        90       100       110       120       130       140       150
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 33286446 584 PSPAGPtrdEPAESPSETPGPRPAGPAGDEP---AESPSETPGPRPAGPAGDEPAESPSETPGPSPAGPT 650
Cdd:cd21576 109 ASSGSS---DPARGSSPTLGSEPAPASGEDAvsgPESSFGAPAIPSAPAAPGAPAVSGEVPGGAPGAGPA 175
PHA03291 PHA03291
envelope glycoprotein I; Provisional
510-625 2.80e-03

envelope glycoprotein I; Provisional


Pssm-ID: 223033 [Multi-domain]  Cd Length: 401  Bit Score: 40.71  E-value: 2.80e-03
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 33286446  510 PKEGTPGSPSETPGPSPAGPAGDEPAESPSETPGP--RPAGP-AGDEPAESPSETPGPrpagPAGDEPAESPSETPGPSP 586
Cdd:PHA03291 167 PAEGTLAAPPLGEGSADGSCDPALPLSAPRLGPADvfVPATPrPTPRTTASPETTPTP----STTTSPPSTTIPAPSTTI 242
                         90       100       110
                 ....*....|....*....|....*....|....*....
gi 33286446  587 AGPtrdEPAESPSETPGPRPAGPAGDEPAESPSeTPGPR 625
Cdd:PHA03291 243 AAP---QAGTTPEAEGTPAPPTPGGGEAPPANA-TPAPE 277
DLIC pfam05783
Dynein light intermediate chain (DLIC); This family consists of several eukaryotic dynein ...
587-675 2.96e-03

Dynein light intermediate chain (DLIC); This family consists of several eukaryotic dynein light intermediate chain proteins. The light intermediate chains (LICs) of cytoplasmic dynein consist of multiple isoforms, which undergo post-translational modification to produce a large number of species. DLIC1 is known to be involved in assembly, organization, and function of centrosomes and mitotic spindles when bound to pericentrin. DLIC2 is a subunit of cytoplasmic dynein 2 that may play a role in maintaining Golgi organization by binding cytoplasmic dynein 2 to its Golgi-associated cargo.


Pssm-ID: 368612  Cd Length: 468  Bit Score: 40.60  E-value: 2.96e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 33286446   587 AGPTRDEPAESPSETPGPRPAGPAGDEPAESPSETPGPRPAGPAGDEPAESPSE------------TPGPSPAGPTRDEP 654
Cdd:pfam05783 344 QPATPTRGVESPARSPSGSPRTTNRSGPANVASVSPQTSVKKIDPNMKPGAASEgvlanffnsllsKKTGSPGGGSPGGG 423
                          90       100
                  ....*....|....*....|.
gi 33286446   655 AKAGEAAELQDAEVESSAKSG 675
Cdd:pfam05783 424 TGSGRGSNVQDSAKKSGQKPV 444
PHA03269 PHA03269
envelope glycoprotein C; Provisional
553-655 3.49e-03

envelope glycoprotein C; Provisional


Pssm-ID: 165527 [Multi-domain]  Cd Length: 566  Bit Score: 40.48  E-value: 3.49e-03
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 33286446  553 EPAESPSE--TPGPRPAGPAGDEPAESPSETPGPSPAGPTRDEPAESPSETPGPRPagpagdEPAESPS--ETPGPRPAG 628
Cdd:PHA03269  41 DPAPAPHQaaSRAPDPAVAPTSAASRKPDLAQAPTPAASEKFDPAPAPHQAASRAP------DPAVAPQlaAAPKPDAAE 114
                         90       100
                 ....*....|....*....|....*..
gi 33286446  629 PAGDEPAESPSETPGPSPAGPTRDEPA 655
Cdd:PHA03269 115 AFTSAAQAHEAPADAGTSAASKKPDPA 141
PspC_subgroup_2 NF033839
pneumococcal surface protein PspC, LPXTG-anchored form; The pneumococcal surface protein PspC, ...
483-637 4.00e-03

pneumococcal surface protein PspC, LPXTG-anchored form; The pneumococcal surface protein PspC, as described in Streptococcus pneumoniae, is a repetitive and highly variable protein, recognized by a conserved N-terminal domain and also by genomic location. This form, subgroup 2, is anchored covalently after cleavage by sortase at a C-terminal LPXTG site. The other form, subgroup 1, has variable numbers of a choline-binding repeat in the C-terminal region, and is also known as choline-binding protein A.


Pssm-ID: 468202 [Multi-domain]  Cd Length: 557  Bit Score: 40.14  E-value: 4.00e-03
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 33286446  483 GSPAPSGHPKAGHSENGVEEDTEGRTGPKEGTPGSPSETPGPSPAGPAGD--EPAESPSETPGPRPAGPagdepaeSPSE 560
Cdd:NF033839 348 ETPKPEVKPQPEKPKPEVKPQPEKPKPEVKPQPETPKPEVKPQPEKPKPEvkPQPEKPKPEVKPQPEKP-------KPEV 420
                         90       100       110       120       130       140       150
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 33286446  561 TPGPRPAGPAGDEPAESPSETPGPSPAGPTRDEPAESPSETPGPRPAgPAGDEPAESPS-ETPGPRPAGPAGDEPAES 637
Cdd:NF033839 421 KPQPEKPKPEVKPQPEKPKPEVKPQPEKPKPEVKPQPETPKPEVKPQ-PEKPKPEVKPQpEKPKPDNSKPQADDKKPS 497
PHA03321 PHA03321
tegument protein VP11/12; Provisional
507-671 4.28e-03

tegument protein VP11/12; Provisional


Pssm-ID: 223041 [Multi-domain]  Cd Length: 694  Bit Score: 40.33  E-value: 4.28e-03
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 33286446  507 RTGPKEGTPGSPSETPGPSPAGPAGDEPAESPSETPGPRPAGPAGDEPAESPSETPGPRPAGPAgdepaespseTPGPSP 586
Cdd:PHA03321 423 RLLSSRQPPGAPAPRRDNDPPPPPRARPGSTPACARRARAQRARDAGPEYVDPLGALRRLPAGA----------APPPEP 492
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 33286446  587 AGPTRdePAESPSETPGPRPAGPAGDEPAESPSETPGPRPAGPAgdEPAESPSETPGPSPAGPTRDEPAKAGEAAELQDA 666
Cdd:PHA03321 493 AAAPS--PATYYTRMGGGPPRLPPRNRATETLRPDWGPPAAAPP--EQMEDPYLEPDDDRFDRRDGAAAAATSHPREAPA 568

                 ....*
gi 33286446  667 EVESS 671
Cdd:PHA03321 569 PDDDP 573
PspC_subgroup_2 NF033839
pneumococcal surface protein PspC, LPXTG-anchored form; The pneumococcal surface protein PspC, ...
502-653 4.59e-03

pneumococcal surface protein PspC, LPXTG-anchored form; The pneumococcal surface protein PspC, as described in Streptococcus pneumoniae, is a repetitive and highly variable protein, recognized by a conserved N-terminal domain and also by genomic location. This form, subgroup 2, is anchored covalently after cleavage by sortase at a C-terminal LPXTG site. The other form, subgroup 1, has variable numbers of a choline-binding repeat in the C-terminal region, and is also known as choline-binding protein A.


Pssm-ID: 468202 [Multi-domain]  Cd Length: 557  Bit Score: 40.14  E-value: 4.59e-03
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 33286446  502 EDTEGRTGPKEGTPGSPSETPGPSPAGPAGDEpAESPSETPGPRPAGPAGDEPAESPSETPGPRPAGPagdepaeSPSET 581
Cdd:NF033839 350 PKPEVKPQPEKPKPEVKPQPEKPKPEVKPQPE-TPKPEVKPQPEKPKPEVKPQPEKPKPEVKPQPEKP-------KPEVK 421
                         90       100       110       120       130       140       150
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 33286446  582 PGPSPAGPTRDEPAESPSETPGPRPAGPAGDEPAESPSETPGPRPAgPAGDEPAESPS-ETPGPSPAGPTRDE 653
Cdd:NF033839 422 PQPEKPKPEVKPQPEKPKPEVKPQPEKPKPEVKPQPETPKPEVKPQ-PEKPKPEVKPQpEKPKPDNSKPQADD 493
PRK14959 PRK14959
DNA polymerase III subunits gamma and tau; Provisional
506-625 4.61e-03

DNA polymerase III subunits gamma and tau; Provisional


Pssm-ID: 184923 [Multi-domain]  Cd Length: 624  Bit Score: 40.05  E-value: 4.61e-03
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 33286446  506 GRTGPKEGTPGSPSETPGPSPAGPAGDEPAESPSetpgPRPAGPAGDEPAESPS------ETPgprPAGPAGDEPAESPS 579
Cdd:PRK14959 382 SGSAAEGPASGGAATIPTPGTQGPQGTAPAAGMT----PSSAAPATPAPSAAPSprvpwdDAP---PAPPRSGIPPRPAP 454
                         90       100       110       120
                 ....*....|....*....|....*....|....*....|....*.
gi 33286446  580 ETPGPSPAgPTRDEPAESPSETPgprPAGPAGDEPAesPSETPGPR 625
Cdd:PRK14959 455 RMPEASPV-PGAPDSVASASDAP---PTLGDPSDTA--EHTPSGPR 494
kgd PRK12270
multifunctional oxoglutarate decarboxylase/oxoglutarate dehydrogenase thiamine ...
495-578 4.65e-03

multifunctional oxoglutarate decarboxylase/oxoglutarate dehydrogenase thiamine pyrophosphate-binding subunit/dihydrolipoyllysine-residue succinyltransferase subunit;


Pssm-ID: 237030 [Multi-domain]  Cd Length: 1228  Bit Score: 40.26  E-value: 4.65e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 33286446   495 HSENGVEEDTEGRTGPKEGTPGSPSETPGPSPAGPAGDEPAESPSETPGPRPAgPAGDEPAESPSETPGPRPAGPAGDEP 574
Cdd:PRK12270   37 GPGSTAAPTAAAAAAAAAASAPAAAPAAKAPAAPAPAPPAAAAPAAPPKPAAA-AAAAAAPAAPPAAAAAAAPAAAAVED 115

                  ....
gi 33286446   575 AESP 578
Cdd:PRK12270  116 EVTP 119
PHA03321 PHA03321
tegument protein VP11/12; Provisional
442-661 4.66e-03

tegument protein VP11/12; Provisional


Pssm-ID: 223041 [Multi-domain]  Cd Length: 694  Bit Score: 40.33  E-value: 4.66e-03
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 33286446  442 PCRQPLGARVADKVRKRRKVDEGAGDSAAVASGGAQTLALAGSPAPSGHpKAGHSENGVEEDTEGRTGPKEGTPGSPSET 521
Cdd:PHA03321 445 PPRARPGSTPACARRARAQRARDAGPEYVDPLGALRRLPAGAAPPPEPA-AAPSPATYYTRMGGGPPRLPPRNRATETLR 523
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 33286446  522 P--GPSPAGPAGDE--PAESPSETPGPRPAGPAGdepaesPSETPGPRPAGPAGDEPAESPSETpgpspAGPTRDE-PAE 596
Cdd:PHA03321 524 PdwGPPAAAPPEQMedPYLEPDDDRFDRRDGAAA------AATSHPREAPAPDDDPIYEGVSDS-----EEPVYEEiPTP 592
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 33286446  597 SPSETPGPRPAGPAGDEPAESPSETP-----------------GPRPA---GPAGDEPAESPSETPGPSPAGPTRDEPAK 656
Cdd:PHA03321 593 RVYQNPLPRPMEGAGEPPDLDAPTSPwveeenpiygwgdsplfSPPPAarfPPPDPALSPEPPALPAHRPRPGALAPDGP 672

                 ....*
gi 33286446  657 AGEAA 661
Cdd:PHA03321 673 ANLAA 677
Atrophin-1 pfam03154
Atrophin-1 family; Atrophin-1 is the protein product of the dentatorubral-pallidoluysian ...
518-644 4.67e-03

Atrophin-1 family; Atrophin-1 is the protein product of the dentatorubral-pallidoluysian atrophy (DRPLA) gene. DRPLA OMIM:125370 is a progressive neurodegenerative disorder. It is caused by the expansion of a CAG repeat in the DRPLA gene on chromosome 12p. This results in an extended polyglutamine region in atrophin-1, that is thought to confer toxicity to the protein, possibly through altering its interactions with other proteins. The expansion of a CAG repeat is also the underlying defect in six other neurodegenerative disorders, including Huntington's disease. One interaction of expanded polyglutamine repeats that is thought to be pathogenic is that with the short glutamine repeat in the transcriptional coactivator CREB binding protein, CBP. This interaction draws CBP away from its usual nuclear location to the expanded polyglutamine repeat protein aggregates that are characteriztic of the polyglutamine neurodegenerative disorders. This interferes with CBP-mediated transcription and causes cytotoxicity.


Pssm-ID: 460830 [Multi-domain]  Cd Length: 991  Bit Score: 40.14  E-value: 4.67e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 33286446   518 PSETPGPSPAGPAGDEPAESPSETP-GPRPAGPAgdePAESPSETPGPRPAGPAGDEPAESPSeTPGPSPAGPTRDEPAE 596
Cdd:pfam03154 286 PSHMQHPVPPQPFPLTPQSSQSQVPpGPSPAAPG---QSQQRIHTPPSQSQLQSQQPPREQPL-PPAPLSMPHIKPPPTT 361
                          90       100       110       120       130
                  ....*....|....*....|....*....|....*....|....*....|..
gi 33286446   597 SPSETPGPR----PAGPAGDEPAESPSETPGPRPAGPAGDEPAESPSETPGP 644
Cdd:pfam03154 362 PIPQLPNPQshkhPPHLSGPSPFQMNSNLPPPPALKPLSSLSTHHPPSAHPP 413
PHA03291 PHA03291
envelope glycoprotein I; Provisional
529-645 4.72e-03

envelope glycoprotein I; Provisional


Pssm-ID: 223033 [Multi-domain]  Cd Length: 401  Bit Score: 39.94  E-value: 4.72e-03
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 33286446  529 PAGDEPAESPS-ETPGPRPAGPAgdepaeSPSETPGPRPAG---PAGDEPAESPSETPGPSPAGPTRDEPAESPSETPGP 604
Cdd:PHA03291 167 PAEGTLAAPPLgEGSADGSCDPA------LPLSAPRLGPADvfvPATPRPTPRTTASPETTPTPSTTTSPPSTTIPAPST 240
                         90       100       110       120
                 ....*....|....*....|....*....|....*....|.
gi 33286446  605 RPAGPagdEPAESPSETPGPRPAGPAGDEPAESPSeTPGPS 645
Cdd:PHA03291 241 TIAAP---QAGTTPEAEGTPAPPTPGGGEAPPANA-TPAPE 277
PRK07764 PRK07764
DNA polymerase III subunits gamma and tau; Validated
591-677 5.06e-03

DNA polymerase III subunits gamma and tau; Validated


Pssm-ID: 236090 [Multi-domain]  Cd Length: 824  Bit Score: 39.97  E-value: 5.06e-03
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 33286446  591 RDEPAESPSETPGPRPAGPAGDEPAESPSEtPGPRPAGPAGDEPAESPSETPGPSPAGPTRDEPAKAGEAAELQDAEVES 670
Cdd:PRK07764 383 RRLGVAGGAGAPAAAAPSAAAAAPAAAPAP-AAAAPAAAAAPAPAAAPQPAPAPAPAPAPPSPAGNAPAGGAPSPPPAAA 461

                 ....*..
gi 33286446  671 SAKSGKP 677
Cdd:PRK07764 462 PSAQPAP 468
PHA03291 PHA03291
envelope glycoprotein I; Provisional
549-662 5.33e-03

envelope glycoprotein I; Provisional


Pssm-ID: 223033 [Multi-domain]  Cd Length: 401  Bit Score: 39.55  E-value: 5.33e-03
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 33286446  549 PAGDEPAESPS-ETPGPRPAGPagDEPAESPSETPGP--SPAGPTRD-EPAESPSETPGPrpagPAGDEPAESPSETPGP 624
Cdd:PHA03291 167 PAEGTLAAPPLgEGSADGSCDP--ALPLSAPRLGPADvfVPATPRPTpRTTASPETTPTP----STTTSPPSTTIPAPST 240
                         90       100       110
                 ....*....|....*....|....*....|....*...
gi 33286446  625 RPAGPAGDEPAESPsETPGPSPAGPTRDEPAKAGEAAE 662
Cdd:PHA03291 241 TIAAPQAGTTPEAE-GTPAPPTPGGGEAPPANATPAPE 277
COG5373 COG5373
Uncharacterized membrane protein [Function unknown];
572-643 5.50e-03

Uncharacterized membrane protein [Function unknown];


Pssm-ID: 444140 [Multi-domain]  Cd Length: 854  Bit Score: 39.98  E-value: 5.50e-03
                        10        20        30        40        50        60        70
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 33286446 572 DEPAESPSETPGPSPAGPTRDEPAESPseTPGPRPAgPAGDEPAESPSETPGPRPA---GPAGDEPAESPSETPG 643
Cdd:COG5373  35 AELAEAAEAASAPAEPEPEAAAAATAA--APEAAPA-PVPEAPAAPPAAAEAPAPAaaaPPAEAEPAAAPAAASS 106
KAR9 pfam08580
Yeast cortical protein KAR9; The KAR9 protein in Saccharomyces cerevisiae is a cytoskeletal ...
495-651 5.87e-03

Yeast cortical protein KAR9; The KAR9 protein in Saccharomyces cerevisiae is a cytoskeletal protein required for karyogamy, correct positioning of the mitotic spindle and for orientation of cytoplasmic microtubules. KAR9 localizes at the shmoo tip in mating cells and at the tip of the growing bud in anaphase.


Pssm-ID: 430088 [Multi-domain]  Cd Length: 684  Bit Score: 39.81  E-value: 5.87e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 33286446   495 HSENGVEEDTEGRTGPKEGTPGSPSETPGPSPAGPAGDEPAESPSETPGPR-PAGPAGDEPAESPSETPGPR----PAGP 569
Cdd:pfam08580 403 DSLSSIFEDKNMHDTEDSPATLVANKTPGSSPPSSVIMTPVNKGSKTPSSRrGSSFDFGSSSERVINSKLRResklPQIA 482
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 33286446   570 AGDEPAESPSETPGPSPAGPTRdepAESPSETPGPRPAGPAGDEPAESPSETPGPRPAGPAGDEPAE-------SPSETP 642
Cdd:pfam08580 483 STLKQTKRPSKIPRASPNHSGF---LSTPSNTATSETPTPALRPPSRPQPPPPGNRPRWNASTNTNDldvghnfKPLTLT 559

                  ....*....
gi 33286446   643 GPSPAgPTR 651
Cdd:pfam08580 560 TPSPT-PSR 567
PRK13108 PRK13108
prolipoprotein diacylglyceryl transferase; Reviewed
527-677 6.39e-03

prolipoprotein diacylglyceryl transferase; Reviewed


Pssm-ID: 237284 [Multi-domain]  Cd Length: 460  Bit Score: 39.58  E-value: 6.39e-03
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 33286446  527 AGPAGDEPAE-SPSETPGPRPAGPAGDEPAESPSETPGP-RPAGPAGDEPAESPSETPGPSPAGPTRDEPAESPSETPGP 604
Cdd:PRK13108 288 SEYVVDEALErEPAELAAAAVASAASAVGPVGPGEPNQPdDVAEAVKAEVAEVTDEVAAESVVQVADRDGESTPAVEETS 367
                         90       100       110       120       130       140       150
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 33286446  605 RPagpagDEPAESPSETPGPRPAGPAGDEPAES-----PSETPGPSPAGPTRDEPAK-AGEAAELQDAEVESSAKSGKP 677
Cdd:PRK13108 368 EA-----DIEREQPGDLAGQAPAAHQVDAEAASaapeePAALASEAHDETEPEVPEKaAPIPDPAKPDELAVAGPGDDP 441
PHA03325 PHA03325
nuclear-egress-membrane-like protein; Provisional
508-648 6.69e-03

nuclear-egress-membrane-like protein; Provisional


Pssm-ID: 223044  Cd Length: 418  Bit Score: 39.48  E-value: 6.69e-03
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 33286446  508 TGPKEGTPGSPSETPGP--SPAGPAGDEPAESPSETPGPrpaGPAGDEPAESPSETPGPRPAGPAGDEPAESPSETPGPS 585
Cdd:PHA03325 266 SSLPTSAPKRRSRRAGAmrAAAGETADLADDDGSEHSDP---EPLPASLPPPPVRRPRVKHPEAGKEEPDGARNAEAKEP 342
                         90       100       110       120       130       140
                 ....*....|....*....|....*....|....*....|....*....|....*....|...
gi 33286446  586 PAGPTRDEPAESPSETPGPRPAGPAGDEPAESPSETPGPRPAGPAGDEPAeSPSETPGPSPAG 648
Cdd:PHA03325 343 AQPATSTSSKGSSSAQNKDSGSTGPGSSLAAASSFLEDDDFGSPPLDLTT-SLRHMPSPSVTS 404
PspC_subgroup_1 NF033838
pneumococcal surface protein PspC, choline-binding form; The pneumococcal surface protein PspC, ...
572-658 6.91e-03

pneumococcal surface protein PspC, choline-binding form; The pneumococcal surface protein PspC, as described in Streptococcus pneumoniae, is a repetitive and highly variable protein, recognized by a conserved N-terminal domain and also by genomic location. This form, subgroup 1, has variable numbers of a choline-binding repeat in the C-terminal region, and is also known as choline-binding protein A. The other form, subgroup 2, is anchored covalently after cleavage by sortase at a C-terminal LPXTG site.


Pssm-ID: 468201 [Multi-domain]  Cd Length: 684  Bit Score: 39.61  E-value: 6.91e-03
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 33286446  572 DEPAESPSETPGPSPAgptrdePAespSETPGPRPAGPAGDEPAESPSETPGPRP-AGPAGDEPAESPSETPgPSPAGPT 650
Cdd:NF033838 410 DKVKEKPAEQPQPAPA------PQ---PEKPAPKPEKPAEQPKAEKPADQQAEEDyARRSEEEYNRLTQQQP-PKTEKPA 479

                 ....*...
gi 33286446  651 RDEPAKAG 658
Cdd:NF033838 480 QPSTPKTG 487
DUF4045 pfam13254
Domain of unknown function (DUF4045); This presumed domain is functionally uncharacterized. ...
458-626 6.96e-03

Domain of unknown function (DUF4045); This presumed domain is functionally uncharacterized. This domain family is found in bacteria and eukaryotes, and is typically between 384 and 430 amino acids in length.


Pssm-ID: 433066 [Multi-domain]  Cd Length: 415  Bit Score: 39.38  E-value: 6.96e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 33286446   458 RRKVDEGAGDSAAVASggaqTLALAGSPAPSGHPKaghsengveedtegrtgpkegTPGSPSETPGPSPAGPAGDEPAES 537
Cdd:pfam13254 189 RASVDLGRPNSFKEVT----PVGLMRSPAPGGHSK---------------------SPSVSGISADSSPTKEEPSEEADT 243
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 33286446   538 PSETPGPRPAGPAGDEPAESPSETPGPRPAGPAGDEPAESPSETPGPS-PAGPTRDEPAESP---SETPGPRPAGPAGDE 613
Cdd:pfam13254 244 LSTDKEQSPAPTSASEPPPKTKELPKDSEEPAAPSKSAEASTEKKEPDtESSPETSSEKSAPsllSPVSKASIDKPLSSP 323
                         170
                  ....*....|...
gi 33286446   614 PAESPSETPGPRP 626
Cdd:pfam13254 324 DRDPLSPKPKPQS 336
PRK10856 PRK10856
cytoskeleton protein RodZ;
549-639 7.67e-03

cytoskeleton protein RodZ;


Pssm-ID: 236776 [Multi-domain]  Cd Length: 331  Bit Score: 38.85  E-value: 7.67e-03
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 33286446  549 PAGDEPAESPSETPGPRPAGPAGDEPAESPSETPGPSPAGPTRDEPAESPSETPGPRPAGPAgdEPAESPSETPGPRPAG 628
Cdd:PRK10856 163 PLDTSTTTDPATTPAPAAPVDTTPTNSQTPAVATAPAPAVDPQQNAVVAPSQANVDTAATPA--PAAPATPDGAAPLPTD 240
                         90
                 ....*....|..
gi 33286446  629 PAGDE-PAESPS 639
Cdd:PRK10856 241 QAGVStPAADPN 252
COG5373 COG5373
Uncharacterized membrane protein [Function unknown];
532-603 7.94e-03

Uncharacterized membrane protein [Function unknown];


Pssm-ID: 444140 [Multi-domain]  Cd Length: 854  Bit Score: 39.60  E-value: 7.94e-03
                        10        20        30        40        50        60        70
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 33286446 532 DEPAESPSETPGPRPAGPAGDEPAespseTPGPRPAgPAGDEPAESPSETPGPSPA---GPTRDEPAESPSETPG 603
Cdd:COG5373  38 AEAAEAASAPAEPEPEAAAAATAA-----APEAAPA-PVPEAPAAPPAAAEAPAPAaaaPPAEAEPAAAPAAASS 106
motB PRK05996
MotB family protein;
524-611 8.49e-03

MotB family protein;


Pssm-ID: 235665 [Multi-domain]  Cd Length: 423  Bit Score: 38.91  E-value: 8.49e-03
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 33286446  524 PSPAGPAGDEPAESPSETPGPRPAGPAGDEPAESPSETPGPRPA------GPAGDEPAES-PSETPGPSPAgpTRDEPAE 596
Cdd:PRK05996 198 LLPPGQAREQAQGAKSATAAPATVPQAAPLPQAQPKKAATEEELiadakkAATGEPAANAaKAAKPEPMPD--DQQKEAE 275
                         90
                 ....*....|....*
gi 33286446  597 SPSETPGPRPAGPAG 611
Cdd:PRK05996 276 QLQAAIAQAIGGVAG 290
flhF PRK06995
flagellar biosynthesis protein FlhF;
554-656 8.53e-03

flagellar biosynthesis protein FlhF;


Pssm-ID: 235904 [Multi-domain]  Cd Length: 484  Bit Score: 39.18  E-value: 8.53e-03
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 33286446  554 PAESPSETPGPRPAgPAGDEPAESPSETPGPSPAGPTR--DEPAESPSETPGPRPAGPAGDEPAESPSETPGPRPAGPAG 631
Cdd:PRK06995  56 AAAPAAAQPPPAAA-PAAVSRPAAPAAEPAPWLVEHAKrlTAQREQLVARAAAPAAPEAQAPAAPAERAAAENAARRLAR 134
                         90       100
                 ....*....|....*....|....*
gi 33286446  632 DEPAESPSETPGPSPAGPTRDEPAK 656
Cdd:PRK06995 135 AAAAAPRPRVPADAAAAVADAVKAR 159
PHA03201 PHA03201
uracil DNA glycosylase; Provisional
510-598 9.02e-03

uracil DNA glycosylase; Provisional


Pssm-ID: 165468  Cd Length: 318  Bit Score: 38.72  E-value: 9.02e-03
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 33286446  510 PKEGTPGSPSETPGPSPAGPAGdePAESPSETPgPRPAGPAGDEPAESPSETPGPRpAGPAGDEPAESPSETPGPSPAGP 589
Cdd:PHA03201   4 ARSRSPSPPRRPSPPRPTPPRS--PDASPEETP-PSPPGPGAEPPPGRAAGPAAPR-RRPRGCPAGVTFSSSAPPRPPLG 79

                 ....*....
gi 33286446  590 TRDEPAESP 598
Cdd:PHA03201  80 LDDAPAATP 88
PRK14950 PRK14950
DNA polymerase III subunits gamma and tau; Provisional
510-580 9.03e-03

DNA polymerase III subunits gamma and tau; Provisional


Pssm-ID: 237864 [Multi-domain]  Cd Length: 585  Bit Score: 39.02  E-value: 9.03e-03
                         10        20        30        40        50        60        70
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 33286446  510 PKEGTPGsPSETPGPSPAG---PAGDEPAESPSETPGPRPAGPAGDEPAESPSETPG---PRPAGPAGDEPAESPSE 580
Cdd:PRK14950 378 PVRPTPA-PSTRPKAAAAAnipPKEPVRETATPPPVPPRPVAPPVPHTPESAPKLTRaaiPVDEKPKYTPPAPPKEE 453
PHA03377 PHA03377
EBNA-3C; Provisional
485-658 9.09e-03

EBNA-3C; Provisional


Pssm-ID: 177614 [Multi-domain]  Cd Length: 1000  Bit Score: 39.27  E-value: 9.09e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 33286446   485 PAPSGHPKAghSENGVEEDTEGRTGPKEGTPgspsETPGPSPAGPagdEPAESPSETPGPRPAGPAGDEPAESPSET--P 562
Cdd:PHA03377  422 PTPKTHPVK--RTLVKTSGRSDEAEQAQSTP----ERPGPSDQPS---VPVEPAHLTPVEHTTVILHQPPQSPPTVAikP 492
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 33286446   563 GPRPAG-PAG------DEPAE------SPSETPGPSPAGPTRDE----------------PAESPSET----PGPRPAGP 609
Cdd:PHA03377  493 APPPSRrRRGacvvydDDIIEvidvetTEEEESVTQPAKPHRKVqdgfqrsgrrqkratpPKVSPSDRgppkASPPVMAP 572
                         170       180       190       200
                  ....*....|....*....|....*....|....*....|....*....
gi 33286446   610 AGDEPAESPSETPGPRPAGPAGDEPAESPSETPGPSPAGPTRDEPAKAG 658
Cdd:PHA03377  573 PSTGPRVMATPSTGPRDMAPPSTGPRQQAKCKDGPPASGPHEKQPPSSA 621
rad23 TIGR00601
UV excision repair protein Rad23; All proteins in this family for which functions are known ...
544-623 9.52e-03

UV excision repair protein Rad23; All proteins in this family for which functions are known are components of a multiprotein complex used for targeting nucleotide excision repair to specific parts of the genome. In humans, Rad23 complexes with the XPC protein. This family is based on the phylogenomic analysis of JA Eisen (1999, Ph.D. Thesis, Stanford University). [DNA metabolism, DNA replication, recombination, and repair]


Pssm-ID: 273167 [Multi-domain]  Cd Length: 378  Bit Score: 38.72  E-value: 9.52e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 33286446   544 PRPAGPAGDEPAESPSETPGPRPAGPAgdepaeSPSETPGPSPAGpTRDEPAESPSETPGPRPAGPAGDEPAESPSETPG 623
Cdd:TIGR00601  77 PKTGTGKVAPPAATPTSAPTPTPSPPA------SPASGMSAAPAS-AVEEKSPSEESATATAPESPSTSVPSSGSDAAST 149
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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