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Conserved domains on  [gi|6671620|ref|NP_031556|]
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B-cell receptor-associated protein 29 [Mus musculus]

Protein Classification

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
Bap31 pfam05529
Bap31/Bap29 transmembrane region; Bap31 is a polytopic integral protein of the endoplasmic ...
 1-129 1.27e-48

Bap31/Bap29 transmembrane region; Bap31 is a polytopic integral protein of the endoplasmic reticulum membrane and a substrate of caspase-8. Bap31 is cleaved within its cytosolic domain, generating pro-apoptotic p20 Bap31. This family also contains the Bap29 protein that forms a heterodimer with Bap 31.


:

Pssm-ID: 461673  Cd Length: 137  Bit Score: 156.50  E-value: 1.27e-48
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6671620      1 MTIQWAAVASFLYAEIGLILLFCLPFIPPQRwQKIFSFSVWGKIASFWNKAFLTIIILLIILFLDAVREVRKYSS-TNVV 79
Cdd:pfam05529   1 MTLQWTLVFGFLYAEMAVFLLLVLPLPSPVR-QKIFKSRSESPLSAKFQIGFKITIIFLLILFLDAVRRVRKYSAeLESA 79

                          90       100       110       120       130
                  ....*....|....*....|....*....|....*....|....*....|
gi 6671620     80 EKNSAIRPSAFEHTQMKLFRSQRNLYISGFSLFFWLVLRRLVTLITQLAK 129
Cdd:pfam05529  80 KANAHQHPSARMEVQARKFYAQRNLYICGFTLFLSLVLRRTVTLISELAT 129
Bap31_Bap29_C pfam18035
Bap31/Bap29 cytoplasmic coiled-coil domain; Bap31 is a polytopic integral protein of the ...
 184-237 1.48e-08

Bap31/Bap29 cytoplasmic coiled-coil domain; Bap31 is a polytopic integral protein of the endoplasmic reticulum membrane and a substrate of caspase-8. Bap31 is cleaved within its cytosolic domain, generating pro-apoptotic p20 Bap31. This entry represents the cytoplasmic domain which forms a heterodimeric coiled-coil with Bap29. This Bap29 and Bap31 are homologous to each other and this entry includes both proteins.


:

Pssm-ID: 465623 [Multi-domain]  Cd Length: 52  Bit Score: 49.58  E-value: 1.48e-08
                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|....
gi 6671620    184 ENLKTELKKAsdallkaQNDVMTMKIQSERLSKEYDRLLKEHSELQNRLEKEKK 237
Cdd:pfam18035   4 EKLKKELKKK-------KSDIEALKKQAEGLQREYDRLSDEHAKLQLDEGEDKK 50
PLN03188 super family cl33656
kinesin-12 family protein; Provisional
 124-225 8.90e-03

kinesin-12 family protein; Provisional


The actual alignment was detected with superfamily member PLN03188:

Pssm-ID: 215621 [Multi-domain]  Cd Length: 1320  Bit Score: 37.22  E-value: 8.90e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6671620    124 ITQLAKEIAnkgVLKIQAEntnKAAKKFMEENEKLKLGLRnDNAEEhlleaenkklIESKENLKTELKKASDALLKAQND 203
Cdd:PLN03188 1157 INALAAEIS---ALKVERE---KERRYLRDENKSLQAQLR-DTAEA----------VQAAGELLVRLKEAEEALTVAQKR 1219

                          90       100
                  ....*....|....*....|..
gi 6671620    204 VMTMKIQSERLSKEYDRLLKEH 225
Cdd:PLN03188 1220 AMDAEQEAAEAYKQIDKLKRKH 1241
 
Name Accession Description Interval E-value
Bap31 pfam05529
Bap31/Bap29 transmembrane region; Bap31 is a polytopic integral protein of the endoplasmic ...
 1-129 1.27e-48

Bap31/Bap29 transmembrane region; Bap31 is a polytopic integral protein of the endoplasmic reticulum membrane and a substrate of caspase-8. Bap31 is cleaved within its cytosolic domain, generating pro-apoptotic p20 Bap31. This family also contains the Bap29 protein that forms a heterodimer with Bap 31.


Pssm-ID: 461673  Cd Length: 137  Bit Score: 156.50  E-value: 1.27e-48
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6671620      1 MTIQWAAVASFLYAEIGLILLFCLPFIPPQRwQKIFSFSVWGKIASFWNKAFLTIIILLIILFLDAVREVRKYSS-TNVV 79
Cdd:pfam05529   1 MTLQWTLVFGFLYAEMAVFLLLVLPLPSPVR-QKIFKSRSESPLSAKFQIGFKITIIFLLILFLDAVRRVRKYSAeLESA 79

                          90       100       110       120       130
                  ....*....|....*....|....*....|....*....|....*....|
gi 6671620     80 EKNSAIRPSAFEHTQMKLFRSQRNLYISGFSLFFWLVLRRLVTLITQLAK 129
Cdd:pfam05529  80 KANAHQHPSARMEVQARKFYAQRNLYICGFTLFLSLVLRRTVTLISELAT 129
Bap31_Bap29_C pfam18035
Bap31/Bap29 cytoplasmic coiled-coil domain; Bap31 is a polytopic integral protein of the ...
 184-237 1.48e-08

Bap31/Bap29 cytoplasmic coiled-coil domain; Bap31 is a polytopic integral protein of the endoplasmic reticulum membrane and a substrate of caspase-8. Bap31 is cleaved within its cytosolic domain, generating pro-apoptotic p20 Bap31. This entry represents the cytoplasmic domain which forms a heterodimeric coiled-coil with Bap29. This Bap29 and Bap31 are homologous to each other and this entry includes both proteins.


Pssm-ID: 465623 [Multi-domain]  Cd Length: 52  Bit Score: 49.58  E-value: 1.48e-08
                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|....
gi 6671620    184 ENLKTELKKAsdallkaQNDVMTMKIQSERLSKEYDRLLKEHSELQNRLEKEKK 237
Cdd:pfam18035   4 EKLKKELKKK-------KSDIEALKKQAEGLQREYDRLSDEHAKLQLDEGEDKK 50
SMC_prok_B TIGR02168
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...
 117-238 8.08e-03

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274008 [Multi-domain]  Cd Length: 1179  Bit Score: 37.34  E-value: 8.08e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6671620     117 LRRLVTLITQLAKEIANKG-VLKIQAENTNKAAKKFmEENEKLKLGLRNDNAEEHLLEAENKKLIESKENLKTELKKASD 195
Cdd:TIGR02168  311 LANLERQLEELEAQLEELEsKLDELAEELAELEEKL-EELKEELESLEAELEELEAELEELESRLEELEEQLETLRSKVA 389

                           90       100       110       120
                   ....*....|....*....|....*....|....*....|....*..
gi 6671620     196 ALLK----AQNDVMTMKIQSERLSKEYDRLLKEHSELQNRLEKEKKK 238
Cdd:TIGR02168  390 QLELqiasLNNEIERLEARLERLEDRRERLQQEIEELLKKLEEAELK 436
PLN03188 PLN03188
kinesin-12 family protein; Provisional
 124-225 8.90e-03

kinesin-12 family protein; Provisional


Pssm-ID: 215621 [Multi-domain]  Cd Length: 1320  Bit Score: 37.22  E-value: 8.90e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6671620    124 ITQLAKEIAnkgVLKIQAEntnKAAKKFMEENEKLKLGLRnDNAEEhlleaenkklIESKENLKTELKKASDALLKAQND 203
Cdd:PLN03188 1157 INALAAEIS---ALKVERE---KERRYLRDENKSLQAQLR-DTAEA----------VQAAGELLVRLKEAEEALTVAQKR 1219

                          90       100
                  ....*....|....*....|..
gi 6671620    204 VMTMKIQSERLSKEYDRLLKEH 225
Cdd:PLN03188 1220 AMDAEQEAAEAYKQIDKLKRKH 1241
 
Name Accession Description Interval E-value
Bap31 pfam05529
Bap31/Bap29 transmembrane region; Bap31 is a polytopic integral protein of the endoplasmic ...
 1-129 1.27e-48

Bap31/Bap29 transmembrane region; Bap31 is a polytopic integral protein of the endoplasmic reticulum membrane and a substrate of caspase-8. Bap31 is cleaved within its cytosolic domain, generating pro-apoptotic p20 Bap31. This family also contains the Bap29 protein that forms a heterodimer with Bap 31.


Pssm-ID: 461673  Cd Length: 137  Bit Score: 156.50  E-value: 1.27e-48
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6671620      1 MTIQWAAVASFLYAEIGLILLFCLPFIPPQRwQKIFSFSVWGKIASFWNKAFLTIIILLIILFLDAVREVRKYSS-TNVV 79
Cdd:pfam05529   1 MTLQWTLVFGFLYAEMAVFLLLVLPLPSPVR-QKIFKSRSESPLSAKFQIGFKITIIFLLILFLDAVRRVRKYSAeLESA 79

                          90       100       110       120       130
                  ....*....|....*....|....*....|....*....|....*....|
gi 6671620     80 EKNSAIRPSAFEHTQMKLFRSQRNLYISGFSLFFWLVLRRLVTLITQLAK 129
Cdd:pfam05529  80 KANAHQHPSARMEVQARKFYAQRNLYICGFTLFLSLVLRRTVTLISELAT 129
Bap31_Bap29_C pfam18035
Bap31/Bap29 cytoplasmic coiled-coil domain; Bap31 is a polytopic integral protein of the ...
 184-237 1.48e-08

Bap31/Bap29 cytoplasmic coiled-coil domain; Bap31 is a polytopic integral protein of the endoplasmic reticulum membrane and a substrate of caspase-8. Bap31 is cleaved within its cytosolic domain, generating pro-apoptotic p20 Bap31. This entry represents the cytoplasmic domain which forms a heterodimeric coiled-coil with Bap29. This Bap29 and Bap31 are homologous to each other and this entry includes both proteins.


Pssm-ID: 465623 [Multi-domain]  Cd Length: 52  Bit Score: 49.58  E-value: 1.48e-08
                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|....
gi 6671620    184 ENLKTELKKAsdallkaQNDVMTMKIQSERLSKEYDRLLKEHSELQNRLEKEKK 237
Cdd:pfam18035   4 EKLKKELKKK-------KSDIEALKKQAEGLQREYDRLSDEHAKLQLDEGEDKK 50
SCP-1 pfam05483
Synaptonemal complex protein 1 (SCP-1); Synaptonemal complex protein 1 (SCP-1) is the major ...
 118-238 8.25e-05

Synaptonemal complex protein 1 (SCP-1); Synaptonemal complex protein 1 (SCP-1) is the major component of the transverse filaments of the synaptonemal complex. Synaptonemal complexes are structures that are formed between homologous chromosomes during meiotic prophase.


Pssm-ID: 114219 [Multi-domain]  Cd Length: 787  Bit Score: 43.17  E-value: 8.25e-05
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6671620    118 RRLVTLITQLAKEIANkgvLKIQAENTNKAAKKFMEENEKLKLGLRND-------NAEEHLLEAENKKLIESKENLKTEL 190
Cdd:pfam05483 439 QELIFLLQAREKEIHD---LEIQLTAIKTSEEHYLKEVEDLKTELEKEklknielTAHCDKLLLENKELTQEASDMTLEL 515

                          90       100       110       120
                  ....*....|....*....|....*....|....*....|....*...
gi 6671620    191 KKAsdallkaQNDVMTMKIQSERLSKEYDRLLKEHSELQNRLEKEKKK 238
Cdd:pfam05483 516 KKH-------QEDIINCKKQEERMLKQIENLEEKEMNLRDELESVREE 556
SMC_prok_B TIGR02168
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...
 117-238 8.08e-03

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274008 [Multi-domain]  Cd Length: 1179  Bit Score: 37.34  E-value: 8.08e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6671620     117 LRRLVTLITQLAKEIANKG-VLKIQAENTNKAAKKFmEENEKLKLGLRNDNAEEHLLEAENKKLIESKENLKTELKKASD 195
Cdd:TIGR02168  311 LANLERQLEELEAQLEELEsKLDELAEELAELEEKL-EELKEELESLEAELEELEAELEELESRLEELEEQLETLRSKVA 389

                           90       100       110       120
                   ....*....|....*....|....*....|....*....|....*..
gi 6671620     196 ALLK----AQNDVMTMKIQSERLSKEYDRLLKEHSELQNRLEKEKKK 238
Cdd:TIGR02168  390 QLELqiasLNNEIERLEARLERLEDRRERLQQEIEELLKKLEEAELK 436
PLN03188 PLN03188
kinesin-12 family protein; Provisional
 124-225 8.90e-03

kinesin-12 family protein; Provisional


Pssm-ID: 215621 [Multi-domain]  Cd Length: 1320  Bit Score: 37.22  E-value: 8.90e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6671620    124 ITQLAKEIAnkgVLKIQAEntnKAAKKFMEENEKLKLGLRnDNAEEhlleaenkklIESKENLKTELKKASDALLKAQND 203
Cdd:PLN03188 1157 INALAAEIS---ALKVERE---KERRYLRDENKSLQAQLR-DTAEA----------VQAAGELLVRLKEAEEALTVAQKR 1219

                          90       100
                  ....*....|....*....|..
gi 6671620    204 VMTMKIQSERLSKEYDRLLKEH 225
Cdd:PLN03188 1220 AMDAEQEAAEAYKQIDKLKRKH 1241
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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