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Conserved domains on  [gi|52426750|ref|NP_038527|]
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complement component receptor 1-like protein isoform 1 precursor [Mus musculus]

Protein Classification

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
PHA02927 super family cl33700
secreted complement-binding protein; Provisional
 42-295 1.28e-44

secreted complement-binding protein; Provisional


The actual alignment was detected with superfamily member PHA02927:

Pssm-ID: 222943 [Multi-domain]  Cd Length: 263  Bit Score: 156.35  E-value: 1.28e-44
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 52426750   42 CPAPSqlpsaKPINLT--------DESMFPIGTYLLYECLPGYIKRQF-SITCKQDSTWTSAEDKCIRKQCKTPSDPENG 112
Cdd:PHA02927  21 CTIPS-----RPINMKfknsvetdANANYNIGDTIEYLCLPGYRKQKMgPIYAKCTGTGWTLFNQCIKRRCPSPRDIDNG 95

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 52426750  113 LVHVhTGIQFGSRINYTCNQGYRLIGSSSAVCVI-TDQSVDWDTEAPICEWIPCEIPPGIPNGDffSSTREDFHY-GMVV 190
Cdd:PHA02927  96 QLDI-GGVDFGSSITYSCNSGYQLIGESKSYCELgSTGSMVWNPEAPICESVKCQSPPSISNGR--HNGYEDFYTdGSVV 172

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 52426750  191 TYRCNTDargkalFNLVGEPSLYCTSndgeiGVWSGPPpqCIELNKCtPPPYVENAVMLSENRSLFSLRDIVEFRCHPGF 270
Cdd:PHA02927 173 TYSCNSG------YSLIGNSGVLCSG-----GEWSDPP--TCQIVKC-PHPTISNGYLSSGFKRSYSYNDNVDFKCKYGY 238

                        250       260
                 ....*....|....*....|....*
gi 52426750  271 IMKGASSVHCQSLNKWEPELPSCFK 295
Cdd:PHA02927 239 KLSGSSSSTCSPGNTWQPELPKCVR 263
PHA02817 super family cl31508
EEV Host range protein; Provisional
 233-361 4.96e-15

EEV Host range protein; Provisional


The actual alignment was detected with superfamily member PHA02817:

Pssm-ID: 165167 [Multi-domain]  Cd Length: 225  Bit Score: 74.21  E-value: 4.96e-15
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 52426750  233 ELNKCTPPPYVENAVMLSEnRSLFSLRDIVEFRCHPG-----FIMKGASSVHCQSLNKWEPELPSCfKGVICRLPQEMSG 307
Cdd:PHA02817  20 DLNKCCYPPSIKNGYIYNK-KTEYNIGSNVTFFCGNNtrgvrYTLVGEKNIICEKDGKWNKEFPVC-KIIRCRFPALQNG 97

                         90       100       110       120       130
                 ....*....|....*....|....*....|....*....|....*....|....
gi 52426750  308 FQKGLGMKKEYYYGENVTLECEDGYTLEGSSQSQCQSDGSWNPLLAKCVSRSIS 361
Cdd:PHA02817  98 FVNGIPDSKKFYYESEVSFSCKPGFVLIGTKYSVCGINSSWIPKVPICSRDNIT 151
 
Name Accession Description Interval E-value
PHA02927 PHA02927
secreted complement-binding protein; Provisional
 42-295 1.28e-44

secreted complement-binding protein; Provisional


Pssm-ID: 222943 [Multi-domain]  Cd Length: 263  Bit Score: 156.35  E-value: 1.28e-44
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 52426750   42 CPAPSqlpsaKPINLT--------DESMFPIGTYLLYECLPGYIKRQF-SITCKQDSTWTSAEDKCIRKQCKTPSDPENG 112
Cdd:PHA02927  21 CTIPS-----RPINMKfknsvetdANANYNIGDTIEYLCLPGYRKQKMgPIYAKCTGTGWTLFNQCIKRRCPSPRDIDNG 95

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 52426750  113 LVHVhTGIQFGSRINYTCNQGYRLIGSSSAVCVI-TDQSVDWDTEAPICEWIPCEIPPGIPNGDffSSTREDFHY-GMVV 190
Cdd:PHA02927  96 QLDI-GGVDFGSSITYSCNSGYQLIGESKSYCELgSTGSMVWNPEAPICESVKCQSPPSISNGR--HNGYEDFYTdGSVV 172

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 52426750  191 TYRCNTDargkalFNLVGEPSLYCTSndgeiGVWSGPPpqCIELNKCtPPPYVENAVMLSENRSLFSLRDIVEFRCHPGF 270
Cdd:PHA02927 173 TYSCNSG------YSLIGNSGVLCSG-----GEWSDPP--TCQIVKC-PHPTISNGYLSSGFKRSYSYNDNVDFKCKYGY 238

                        250       260
                 ....*....|....*....|....*
gi 52426750  271 IMKGASSVHCQSLNKWEPELPSCFK 295
Cdd:PHA02927 239 KLSGSSSSTCSPGNTWQPELPKCVR 263
PHA02817 PHA02817
EEV Host range protein; Provisional
 233-361 4.96e-15

EEV Host range protein; Provisional


Pssm-ID: 165167 [Multi-domain]  Cd Length: 225  Bit Score: 74.21  E-value: 4.96e-15
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 52426750  233 ELNKCTPPPYVENAVMLSEnRSLFSLRDIVEFRCHPG-----FIMKGASSVHCQSLNKWEPELPSCfKGVICRLPQEMSG 307
Cdd:PHA02817  20 DLNKCCYPPSIKNGYIYNK-KTEYNIGSNVTFFCGNNtrgvrYTLVGEKNIICEKDGKWNKEFPVC-KIIRCRFPALQNG 97

                         90       100       110       120       130
                 ....*....|....*....|....*....|....*....|....*....|....
gi 52426750  308 FQKGLGMKKEYYYGENVTLECEDGYTLEGSSQSQCQSDGSWNPLLAKCVSRSIS 361
Cdd:PHA02817  98 FVNGIPDSKKFYYESEVSFSCKPGFVLIGTKYSVCGINSSWIPKVPICSRDNIT 151
CCP cd00033
Complement control protein (CCP) modules (aka short consensus repeats SCRs or SUSHI repeats) ...
 165-232 1.24e-10

Complement control protein (CCP) modules (aka short consensus repeats SCRs or SUSHI repeats) have been identified in several proteins of the complement system; SUSHI repeats (short complement-like repeat, SCR) are abundant in complement control proteins. The complement control protein (CCP) modules (also known as short consensus repeats SCRs or SUSHI repeats) contain approximately 60 amino acid residues and have been identified in several proteins of the complement system. Typically, 2 to 4 modules contribute to a binding site, implying that the orientation of the modules to each other is critical for function.


Pssm-ID: 153056 [Multi-domain]  Cd Length: 57  Bit Score: 56.70  E-value: 1.24e-10
                        10        20        30        40        50        60
                ....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 52426750 165 CEIPPGIPNGDFfSSTREDFHYGMVVTYRCNTDargkalFNLVGEPSLYCTSNdgeiGVWSGPPPQCI 232
Cdd:cd00033   1 CPPPPVPENGTV-TGSKGSYSYGSTVTYSCNEG------YTLVGSSTITCTEN----GGWSPPPPTCE 57
CCP smart00032
Domain abundant in complement control proteins; SUSHI repeat; short complement-like repeat ...
 237-293 2.12e-10

Domain abundant in complement control proteins; SUSHI repeat; short complement-like repeat (SCR); The complement control protein (CCP) modules (also known as short consensus repeats SCRs or SUSHI repeats) contain approximately 60 amino acid residues and have been identified in several proteins of the complement system. A missense mutation in seventh CCP domain causes deficiency of the b subunit of factor XIII.


Pssm-ID: 214478 [Multi-domain]  Cd Length: 56  Bit Score: 56.00  E-value: 2.12e-10
                           10        20        30        40        50
                   ....*....|....*....|....*....|....*....|....*....|....*..
gi 52426750    237 CTPPPYVENAVMLSENRSlFSLRDIVEFRCHPGFIMKGASSVHCQSLNKWEPELPSC 293
Cdd:smart00032   1 CPPPPDIENGTVTSSSGT-YSYGDTVTYSCDPGYTLIGSSTITCLENGTWSPPPPTC 56
CCP cd00033
Complement control protein (CCP) modules (aka short consensus repeats SCRs or SUSHI repeats) ...
 315-356 1.25e-09

Complement control protein (CCP) modules (aka short consensus repeats SCRs or SUSHI repeats) have been identified in several proteins of the complement system; SUSHI repeats (short complement-like repeat, SCR) are abundant in complement control proteins. The complement control protein (CCP) modules (also known as short consensus repeats SCRs or SUSHI repeats) contain approximately 60 amino acid residues and have been identified in several proteins of the complement system. Typically, 2 to 4 modules contribute to a binding site, implying that the orientation of the modules to each other is critical for function.


Pssm-ID: 153056 [Multi-domain]  Cd Length: 57  Bit Score: 54.01  E-value: 1.25e-09
                        10        20        30        40
                ....*....|....*....|....*....|....*....|..
gi 52426750 315 KKEYYYGENVTLECEDGYTLEGSSQSQCQSDGSWNPLLAKCV 356
Cdd:cd00033  16 KGSYSYGSTVTYSCNEGYTLVGSSTITCTENGGWSPPPPTCE 57
Sushi pfam00084
Sushi repeat (SCR repeat);
237-293 4.36e-09

Sushi repeat (SCR repeat);


Pssm-ID: 459664 [Multi-domain]  Cd Length: 56  Bit Score: 52.12  E-value: 4.36e-09
                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|....*..
gi 52426750   237 CTPPPYVENAVmLSENRSLFSLRDIVEFRCHPGFIMKGASSVHCQSLNKWEPELPSC 293
Cdd:pfam00084   1 CPPPPDIPNGK-VSATKNEYNYGASVSYECDPGYRLVGSPTITCQEDGTWSPPFPEC 56
CCP smart00032
Domain abundant in complement control proteins; SUSHI repeat; short complement-like repeat ...
 315-355 1.50e-08

Domain abundant in complement control proteins; SUSHI repeat; short complement-like repeat (SCR); The complement control protein (CCP) modules (also known as short consensus repeats SCRs or SUSHI repeats) contain approximately 60 amino acid residues and have been identified in several proteins of the complement system. A missense mutation in seventh CCP domain causes deficiency of the b subunit of factor XIII.


Pssm-ID: 214478 [Multi-domain]  Cd Length: 56  Bit Score: 50.60  E-value: 1.50e-08
                           10        20        30        40
                   ....*....|....*....|....*....|....*....|.
gi 52426750    315 KKEYYYGENVTLECEDGYTLEGSSQSQCQSDGSWNPLLAKC 355
Cdd:smart00032  16 SGTYSYGDTVTYSCDPGYTLIGSSTITCLENGTWSPPPPTC 56
Sushi pfam00084
Sushi repeat (SCR repeat);
315-355 1.74e-07

Sushi repeat (SCR repeat);


Pssm-ID: 459664 [Multi-domain]  Cd Length: 56  Bit Score: 47.88  E-value: 1.74e-07
                          10        20        30        40
                  ....*....|....*....|....*....|....*....|.
gi 52426750   315 KKEYYYGENVTLECEDGYTLEGSSQSQCQSDGSWNPLLAKC 355
Cdd:pfam00084  16 KNEYNYGASVSYECDPGYRLVGSPTITCQEDGTWSPPFPEC 56
 
Name Accession Description Interval E-value
PHA02927 PHA02927
secreted complement-binding protein; Provisional
 42-295 1.28e-44

secreted complement-binding protein; Provisional


Pssm-ID: 222943 [Multi-domain]  Cd Length: 263  Bit Score: 156.35  E-value: 1.28e-44
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 52426750   42 CPAPSqlpsaKPINLT--------DESMFPIGTYLLYECLPGYIKRQF-SITCKQDSTWTSAEDKCIRKQCKTPSDPENG 112
Cdd:PHA02927  21 CTIPS-----RPINMKfknsvetdANANYNIGDTIEYLCLPGYRKQKMgPIYAKCTGTGWTLFNQCIKRRCPSPRDIDNG 95

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 52426750  113 LVHVhTGIQFGSRINYTCNQGYRLIGSSSAVCVI-TDQSVDWDTEAPICEWIPCEIPPGIPNGDffSSTREDFHY-GMVV 190
Cdd:PHA02927  96 QLDI-GGVDFGSSITYSCNSGYQLIGESKSYCELgSTGSMVWNPEAPICESVKCQSPPSISNGR--HNGYEDFYTdGSVV 172

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 52426750  191 TYRCNTDargkalFNLVGEPSLYCTSndgeiGVWSGPPpqCIELNKCtPPPYVENAVMLSENRSLFSLRDIVEFRCHPGF 270
Cdd:PHA02927 173 TYSCNSG------YSLIGNSGVLCSG-----GEWSDPP--TCQIVKC-PHPTISNGYLSSGFKRSYSYNDNVDFKCKYGY 238

                        250       260
                 ....*....|....*....|....*
gi 52426750  271 IMKGASSVHCQSLNKWEPELPSCFK 295
Cdd:PHA02927 239 KLSGSSSSTCSPGNTWQPELPKCVR 263
PHA02639 PHA02639
EEV host range protein; Provisional
 165-356 1.18e-21

EEV host range protein; Provisional


Pssm-ID: 165022 [Multi-domain]  Cd Length: 295  Bit Score: 94.73  E-value: 1.18e-21
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 52426750  165 CEIPPGIPNGdFFSSTREDFHYGMVVTYRCNTDargkalFNLVGEPSLYCTsNDGEIGVWSGPPPQCIeLNKCTPPPYVE 244
Cdd:PHA02639  22 CDKPDDISNG-FITELMEKYEIGKLIEYTCNTD------YALIGDRFRTCI-KDKNNAIWSNKAPFCM-LKECNDPPSII 92

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 52426750  245 NAVMLSEnRSLFSLRDIVEFRC--HPG--FIMKGASSVHCQSLNKWEPELPSCfKGVICRLPQEMSGFQKGLGMKKEYYY 320
Cdd:PHA02639  93 NGKIYNK-REMYKVGDEIYYVCneHKGvqYSLVGNEKITCIQDKSWKPDPPIC-KMINCRFPALQNGYINGIPSNKKFYY 170

                        170       180       190
                 ....*....|....*....|....*....|....*.
gi 52426750  321 GENVTLECEDGYTLEGSSQSQCQSDGSWNPLLAKCV 356
Cdd:PHA02639 171 KTRVGFSCKSGFDLVGEKYSTCNINATWFPSIPTCV 206
PHA02639 PHA02639
EEV host range protein; Provisional
 103-295 1.14e-18

EEV host range protein; Provisional


Pssm-ID: 165022 [Multi-domain]  Cd Length: 295  Bit Score: 85.87  E-value: 1.14e-18
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 52426750  103 CKTPSDPENGLV-HVHTGIQFGSRINYTCNQGYRLIGSSSAVCVITDQSVDWDTEAPICEWIPCEIPPGIPNGDFFSStR 181
Cdd:PHA02639  22 CDKPDDISNGFItELMEKYEIGKLIEYTCNTDYALIGDRFRTCIKDKNNAIWSNKAPFCMLKECNDPPSIINGKIYNK-R 100

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 52426750  182 EDFHYGMVVTYRCNtDARGkALFNLVGEPSLYCTSNDGeigvWSGPPPQCIELNkCTPPPYVENAVMLSENRSLFSLRDI 261
Cdd:PHA02639 101 EMYKVGDEIYYVCN-EHKG-VQYSLVGNEKITCIQDKS----WKPDPPICKMIN-CRFPALQNGYINGIPSNKKFYYKTR 173

                        170       180       190
                 ....*....|....*....|....*....|....
gi 52426750  262 VEFRCHPGFIMKGASSVHCQSLNKWEPELPSCFK 295
Cdd:PHA02639 174 VGFSCKSGFDLVGEKYSTCNINATWFPSIPTCVR 207
PHA02817 PHA02817
EEV Host range protein; Provisional
 233-361 4.96e-15

EEV Host range protein; Provisional


Pssm-ID: 165167 [Multi-domain]  Cd Length: 225  Bit Score: 74.21  E-value: 4.96e-15
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 52426750  233 ELNKCTPPPYVENAVMLSEnRSLFSLRDIVEFRCHPG-----FIMKGASSVHCQSLNKWEPELPSCfKGVICRLPQEMSG 307
Cdd:PHA02817  20 DLNKCCYPPSIKNGYIYNK-KTEYNIGSNVTFFCGNNtrgvrYTLVGEKNIICEKDGKWNKEFPVC-KIIRCRFPALQNG 97

                         90       100       110       120       130
                 ....*....|....*....|....*....|....*....|....*....|....
gi 52426750  308 FQKGLGMKKEYYYGENVTLECEDGYTLEGSSQSQCQSDGSWNPLLAKCVSRSIS 361
Cdd:PHA02817  98 FVNGIPDSKKFYYESEVSFSCKPGFVLIGTKYSVCGINSSWIPKVPICSRDNIT 151
PHA02831 PHA02831
EEV host range protein; Provisional
 192-360 1.29e-12

EEV host range protein; Provisional


Pssm-ID: 165176 [Multi-domain]  Cd Length: 268  Bit Score: 67.71  E-value: 1.29e-12
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 52426750  192 YRCNTDargkalFNlvgepSLYCTSNDGEigvWSgPPPQCIELNKCTPPPYVENAvMLSENRSLFSLRDIVEFRCHPGFI 271
Cdd:PHA02831  48 YKCNNN------FD-----KVFVTCNNGS---WS-TKNMCIGKRNCKDPVTILNG-YIKNKKDQYSFGDSVTYACKVNKL 111

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 52426750  272 MK----GASSVHCQSlNKWEPELPSCfKGVICRLPQEMSGFQKGLgmKKEYYYGENVTLECEDGYTLEGSSQSQCQSDGS 347
Cdd:PHA02831 112 EKysivGNETVKCIN-KQWVPKYPVC-KLIRCKYPALQNGFLNVF--EKKFYYGDIVNFKCKKGFILLGSSVSTCDINSI 187

                        170
                 ....*....|...
gi 52426750  348 WNPLLAKCVSRSI 360
Cdd:PHA02831 188 WYPGIPKCVKDKV 200
CCP cd00033
Complement control protein (CCP) modules (aka short consensus repeats SCRs or SUSHI repeats) ...
 165-232 1.24e-10

Complement control protein (CCP) modules (aka short consensus repeats SCRs or SUSHI repeats) have been identified in several proteins of the complement system; SUSHI repeats (short complement-like repeat, SCR) are abundant in complement control proteins. The complement control protein (CCP) modules (also known as short consensus repeats SCRs or SUSHI repeats) contain approximately 60 amino acid residues and have been identified in several proteins of the complement system. Typically, 2 to 4 modules contribute to a binding site, implying that the orientation of the modules to each other is critical for function.


Pssm-ID: 153056 [Multi-domain]  Cd Length: 57  Bit Score: 56.70  E-value: 1.24e-10
                        10        20        30        40        50        60
                ....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 52426750 165 CEIPPGIPNGDFfSSTREDFHYGMVVTYRCNTDargkalFNLVGEPSLYCTSNdgeiGVWSGPPPQCI 232
Cdd:cd00033   1 CPPPPVPENGTV-TGSKGSYSYGSTVTYSCNEG------YTLVGSSTITCTEN----GGWSPPPPTCE 57
CCP smart00032
Domain abundant in complement control proteins; SUSHI repeat; short complement-like repeat ...
 237-293 2.12e-10

Domain abundant in complement control proteins; SUSHI repeat; short complement-like repeat (SCR); The complement control protein (CCP) modules (also known as short consensus repeats SCRs or SUSHI repeats) contain approximately 60 amino acid residues and have been identified in several proteins of the complement system. A missense mutation in seventh CCP domain causes deficiency of the b subunit of factor XIII.


Pssm-ID: 214478 [Multi-domain]  Cd Length: 56  Bit Score: 56.00  E-value: 2.12e-10
                           10        20        30        40        50
                   ....*....|....*....|....*....|....*....|....*....|....*..
gi 52426750    237 CTPPPYVENAVMLSENRSlFSLRDIVEFRCHPGFIMKGASSVHCQSLNKWEPELPSC 293
Cdd:smart00032   1 CPPPPDIENGTVTSSSGT-YSYGDTVTYSCDPGYTLIGSSTITCLENGTWSPPPPTC 56
CCP cd00033
Complement control protein (CCP) modules (aka short consensus repeats SCRs or SUSHI repeats) ...
 237-293 4.97e-10

Complement control protein (CCP) modules (aka short consensus repeats SCRs or SUSHI repeats) have been identified in several proteins of the complement system; SUSHI repeats (short complement-like repeat, SCR) are abundant in complement control proteins. The complement control protein (CCP) modules (also known as short consensus repeats SCRs or SUSHI repeats) contain approximately 60 amino acid residues and have been identified in several proteins of the complement system. Typically, 2 to 4 modules contribute to a binding site, implying that the orientation of the modules to each other is critical for function.


Pssm-ID: 153056 [Multi-domain]  Cd Length: 57  Bit Score: 55.16  E-value: 4.97e-10
                        10        20        30        40        50
                ....*....|....*....|....*....|....*....|....*....|....*..
gi 52426750 237 CTPPPYVENAVMLSENRSlFSLRDIVEFRCHPGFIMKGASSVHCQSLNKWEPELPSC 293
Cdd:cd00033   1 CPPPPVPENGTVTGSKGS-YSYGSTVTYSCNEGYTLVGSSTITCTENGGWSPPPPTC 56
CCP cd00033
Complement control protein (CCP) modules (aka short consensus repeats SCRs or SUSHI repeats) ...
 103-161 6.73e-10

Complement control protein (CCP) modules (aka short consensus repeats SCRs or SUSHI repeats) have been identified in several proteins of the complement system; SUSHI repeats (short complement-like repeat, SCR) are abundant in complement control proteins. The complement control protein (CCP) modules (also known as short consensus repeats SCRs or SUSHI repeats) contain approximately 60 amino acid residues and have been identified in several proteins of the complement system. Typically, 2 to 4 modules contribute to a binding site, implying that the orientation of the modules to each other is critical for function.


Pssm-ID: 153056 [Multi-domain]  Cd Length: 57  Bit Score: 54.78  E-value: 6.73e-10
                        10        20        30        40        50        60
                ....*....|....*....|....*....|....*....|....*....|....*....|
gi 52426750 103 CKTPSDPENGLVHVHTGI-QFGSRINYTCNQGYRLIGSSSAVCVITDQsvdWDTEAPICE 161
Cdd:cd00033   1 CPPPPVPENGTVTGSKGSySYGSTVTYSCNEGYTLVGSSTITCTENGG---WSPPPPTCE 57
PHA02639 PHA02639
EEV host range protein; Provisional
 41-232 8.27e-10

EEV host range protein; Provisional


Pssm-ID: 165022 [Multi-domain]  Cd Length: 295  Bit Score: 59.68  E-value: 8.27e-10
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 52426750   41 HCPAPSQLPSAKPINLTDEsmFPIGTYLLYECLPGY--IKRQFSiTC---KQDSTWTSAEDKCIRKQCKTPSDPENGLVH 115
Cdd:PHA02639  21 YCDKPDDISNGFITELMEK--YEIGKLIEYTCNTDYalIGDRFR-TCikdKNNAIWSNKAPFCMLKECNDPPSIINGKIY 97

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 52426750  116 VHTGI-QFGSRINYTCNQ----GYRLIGSSSAVCVitdQSVDWDTEAPICEWIPCEIPP---GIPNGdffSSTREDFHYG 187
Cdd:PHA02639  98 NKREMyKVGDEIYYVCNEhkgvQYSLVGNEKITCI---QDKSWKPDPPICKMINCRFPAlqnGYING---IPSNKKFYYK 171

                        170       180       190       200
                 ....*....|....*....|....*....|....*....|....*
gi 52426750  188 MVVTYRCntdargKALFNLVGEPSLYCTSNdgeiGVWSGPPPQCI 232
Cdd:PHA02639 172 TRVGFSC------KSGFDLVGEKYSTCNIN----ATWFPSIPTCV 206
CCP smart00032
Domain abundant in complement control proteins; SUSHI repeat; short complement-like repeat ...
 165-231 1.25e-09

Domain abundant in complement control proteins; SUSHI repeat; short complement-like repeat (SCR); The complement control protein (CCP) modules (also known as short consensus repeats SCRs or SUSHI repeats) contain approximately 60 amino acid residues and have been identified in several proteins of the complement system. A missense mutation in seventh CCP domain causes deficiency of the b subunit of factor XIII.


Pssm-ID: 214478 [Multi-domain]  Cd Length: 56  Bit Score: 53.68  E-value: 1.25e-09
                           10        20        30        40        50        60
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 52426750    165 CEIPPGIPNGdFFSSTREDFHYGMVVTYRCNTDargkalFNLVGEPSLYCTSNdgeiGVWSGPPPQC 231
Cdd:smart00032   1 CPPPPDIENG-TVTSSSGTYSYGDTVTYSCDPG------YTLIGSSTITCLEN----GTWSPPPPTC 56
CCP cd00033
Complement control protein (CCP) modules (aka short consensus repeats SCRs or SUSHI repeats) ...
 315-356 1.25e-09

Complement control protein (CCP) modules (aka short consensus repeats SCRs or SUSHI repeats) have been identified in several proteins of the complement system; SUSHI repeats (short complement-like repeat, SCR) are abundant in complement control proteins. The complement control protein (CCP) modules (also known as short consensus repeats SCRs or SUSHI repeats) contain approximately 60 amino acid residues and have been identified in several proteins of the complement system. Typically, 2 to 4 modules contribute to a binding site, implying that the orientation of the modules to each other is critical for function.


Pssm-ID: 153056 [Multi-domain]  Cd Length: 57  Bit Score: 54.01  E-value: 1.25e-09
                        10        20        30        40
                ....*....|....*....|....*....|....*....|..
gi 52426750 315 KKEYYYGENVTLECEDGYTLEGSSQSQCQSDGSWNPLLAKCV 356
Cdd:cd00033  16 KGSYSYGSTVTYSCNEGYTLVGSSTITCTENGGWSPPPPTCE 57
CCP smart00032
Domain abundant in complement control proteins; SUSHI repeat; short complement-like repeat ...
 103-160 2.36e-09

Domain abundant in complement control proteins; SUSHI repeat; short complement-like repeat (SCR); The complement control protein (CCP) modules (also known as short consensus repeats SCRs or SUSHI repeats) contain approximately 60 amino acid residues and have been identified in several proteins of the complement system. A missense mutation in seventh CCP domain causes deficiency of the b subunit of factor XIII.


Pssm-ID: 214478 [Multi-domain]  Cd Length: 56  Bit Score: 52.91  E-value: 2.36e-09
                           10        20        30        40        50
                   ....*....|....*....|....*....|....*....|....*....|....*....
gi 52426750    103 CKTPSDPENGLVHVHTG-IQFGSRINYTCNQGYRLIGSSSAVCVitdQSVDWDTEAPIC 160
Cdd:smart00032   1 CPPPPDIENGTVTSSSGtYSYGDTVTYSCDPGYTLIGSSTITCL---ENGTWSPPPPTC 56
PHA02831 PHA02831
EEV host range protein; Provisional
 68-233 2.98e-09

EEV host range protein; Provisional


Pssm-ID: 165176 [Multi-domain]  Cd Length: 268  Bit Score: 57.69  E-value: 2.98e-09
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 52426750   68 LLYECLPGYIKrqFSITCKQDStWtSAEDKCIRKQ-CKTPSDPENGLV-HVHTGIQFGSRINYTCN----QGYRLIGSSS 141
Cdd:PHA02831  46 LEYKCNNNFDK--VFVTCNNGS-W-STKNMCIGKRnCKDPVTILNGYIkNKKDQYSFGDSVTYACKvnklEKYSIVGNET 121

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 52426750  142 AVCVitdqSVDWDTEAPICEWIPCEIPpGIPNGdFFSSTREDFHYGMVVTYRCNTDargkalFNLVGEPSLYCTSNdgei 221
Cdd:PHA02831 122 VKCI----NKQWVPKYPVCKLIRCKYP-ALQNG-FLNVFEKKFYYGDIVNFKCKKG------FILLGSSVSTCDIN---- 185

                        170
                 ....*....|..
gi 52426750  222 GVWSGPPPQCIE 233
Cdd:PHA02831 186 SIWYPGIPKCVK 197
Sushi pfam00084
Sushi repeat (SCR repeat);
237-293 4.36e-09

Sushi repeat (SCR repeat);


Pssm-ID: 459664 [Multi-domain]  Cd Length: 56  Bit Score: 52.12  E-value: 4.36e-09
                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|....*..
gi 52426750   237 CTPPPYVENAVmLSENRSLFSLRDIVEFRCHPGFIMKGASSVHCQSLNKWEPELPSC 293
Cdd:pfam00084   1 CPPPPDIPNGK-VSATKNEYNYGASVSYECDPGYRLVGSPTITCQEDGTWSPPFPEC 56
CCP smart00032
Domain abundant in complement control proteins; SUSHI repeat; short complement-like repeat ...
 315-355 1.50e-08

Domain abundant in complement control proteins; SUSHI repeat; short complement-like repeat (SCR); The complement control protein (CCP) modules (also known as short consensus repeats SCRs or SUSHI repeats) contain approximately 60 amino acid residues and have been identified in several proteins of the complement system. A missense mutation in seventh CCP domain causes deficiency of the b subunit of factor XIII.


Pssm-ID: 214478 [Multi-domain]  Cd Length: 56  Bit Score: 50.60  E-value: 1.50e-08
                           10        20        30        40
                   ....*....|....*....|....*....|....*....|.
gi 52426750    315 KKEYYYGENVTLECEDGYTLEGSSQSQCQSDGSWNPLLAKC 355
Cdd:smart00032  16 SGTYSYGDTVTYSCDPGYTLIGSSTITCLENGTWSPPPPTC 56
Sushi pfam00084
Sushi repeat (SCR repeat);
103-160 2.22e-08

Sushi repeat (SCR repeat);


Pssm-ID: 459664 [Multi-domain]  Cd Length: 56  Bit Score: 50.19  E-value: 2.22e-08
                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|....*....
gi 52426750   103 CKTPSDPENGLVHV-HTGIQFGSRINYTCNQGYRLIGSSSAVCVITDQsvdWDTEAPIC 160
Cdd:pfam00084   1 CPPPPDIPNGKVSAtKNEYNYGASVSYECDPGYRLVGSPTITCQEDGT---WSPPFPEC 56
Sushi pfam00084
Sushi repeat (SCR repeat);
165-231 3.91e-08

Sushi repeat (SCR repeat);


Pssm-ID: 459664 [Multi-domain]  Cd Length: 56  Bit Score: 49.42  E-value: 3.91e-08
                          10        20        30        40        50        60
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 52426750   165 CEIPPGIPNGDFfSSTREDFHYGMVVTYRCNtdaRGkalFNLVGEPSLYCTSNdgeiGVWSGPPPQC 231
Cdd:pfam00084   1 CPPPPDIPNGKV-SATKNEYNYGASVSYECD---PG---YRLVGSPTITCQED----GTWSPPFPEC 56
Sushi pfam00084
Sushi repeat (SCR repeat);
315-355 1.74e-07

Sushi repeat (SCR repeat);


Pssm-ID: 459664 [Multi-domain]  Cd Length: 56  Bit Score: 47.88  E-value: 1.74e-07
                          10        20        30        40
                  ....*....|....*....|....*....|....*....|.
gi 52426750   315 KKEYYYGENVTLECEDGYTLEGSSQSQCQSDGSWNPLLAKC 355
Cdd:pfam00084  16 KNEYNYGASVSYECDPGYRLVGSPTITCQEDGTWSPPFPEC 56
Sushi pfam00084
Sushi repeat (SCR repeat);
42-98 3.55e-07

Sushi repeat (SCR repeat);


Pssm-ID: 459664 [Multi-domain]  Cd Length: 56  Bit Score: 46.72  E-value: 3.55e-07
                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|....*...
gi 52426750    42 CPAPSQLPSAKPINLTDEsmFPIGTYLLYECLPGYIKR-QFSITCKQDSTWTSAEDKC 98
Cdd:pfam00084   1 CPPPPDIPNGKVSATKNE--YNYGASVSYECDPGYRLVgSPTITCQEDGTWSPPFPEC 56
PHA02954 PHA02954
EEV membrane glycoprotein; Provisional
 103-356 1.29e-06

EEV membrane glycoprotein; Provisional


Pssm-ID: 165263 [Multi-domain]  Cd Length: 317  Bit Score: 50.08  E-value: 1.29e-06
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 52426750  103 CKTPSDPENGLVHVHTGIQFGSRINYTCNQGYRLIgSSSAVCvitdQSVDWDTEAPiCEWIpCEIppgipnGDFFSS--T 180
Cdd:PHA02954  21 CTVPTMNNAKLTSTETSFNDKQKVTFTCDSGYYSL-DPNAVC----ETDKWKYENP-CKKM-CTV------SDYVSElyD 87

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 52426750  181 REDFHYGMVVTYRCNTDARgkalfnlvgepSLYCTSNDGEIGvWSG----PPPQC--IELNKCTPPPYVENavmlsenrs 254
Cdd:PHA02954  88 KPLYEVNSTITLICKDETK-----------YFRCEEKNGNTS-WNDtvtcPNAECqpLQLEHGSCQPVKEK--------- 146

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 52426750  255 lFSLRDIVEFRCHPGFIMKGASSVHCQSlNKWEPeLPSCFKGviCRLPQEMSGFQKGlgmkKEYYYGENVTLECEDGYTL 334
Cdd:PHA02954 147 -YSFGEHITINCDVGYEVIGASYISCTA-NSWNV-IPSCQQK--CDIPSLSNGLISG----STFSIGGVIHLSCKSGFTL 217

                        250       260
                 ....*....|....*....|..
gi 52426750  335 EGSSQSQCqSDGSWNPLLAKCV 356
Cdd:PHA02954 218 TGSPSSTC-IDGKWNPVLPICV 238
PHA02817 PHA02817
EEV Host range protein; Provisional
 98-236 9.39e-06

EEV Host range protein; Provisional


Pssm-ID: 165167 [Multi-domain]  Cd Length: 225  Bit Score: 46.47  E-value: 9.39e-06
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 52426750   98 CIRKQCKTPSDPENGLVH-VHTGIQFGSRINYTCNQG-----YRLIGSSSAVCvitDQSVDWDTEAPICEWIPCEIPP-- 169
Cdd:PHA02817  19 CDLNKCCYPPSIKNGYIYnKKTEYNIGSNVTFFCGNNtrgvrYTLVGEKNIIC---EKDGKWNKEFPVCKIIRCRFPAlq 95

                         90       100       110       120       130       140       150
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 52426750  170 -----GIPNGdffsstrEDFHYGMVVTYRCntdargKALFNLVGEPSLYCTSNDgeigVWSGPPPQCIELNK 236
Cdd:PHA02817  96 ngfvnGIPDS-------KKFYYESEVSFSC------KPGFVLIGTKYSVCGINS----SWIPKVPICSRDNI 150
CCP cd00033
Complement control protein (CCP) modules (aka short consensus repeats SCRs or SUSHI repeats) ...
 42-99 4.40e-05

Complement control protein (CCP) modules (aka short consensus repeats SCRs or SUSHI repeats) have been identified in several proteins of the complement system; SUSHI repeats (short complement-like repeat, SCR) are abundant in complement control proteins. The complement control protein (CCP) modules (also known as short consensus repeats SCRs or SUSHI repeats) contain approximately 60 amino acid residues and have been identified in several proteins of the complement system. Typically, 2 to 4 modules contribute to a binding site, implying that the orientation of the modules to each other is critical for function.


Pssm-ID: 153056 [Multi-domain]  Cd Length: 57  Bit Score: 40.91  E-value: 4.40e-05
                        10        20        30        40        50
                ....*....|....*....|....*....|....*....|....*....|....*....
gi 52426750  42 CPAPSQLPSAKPINLTDEsmFPIGTYLLYECLPGY-IKRQFSITCKQDSTWTSAEDKCI 99
Cdd:cd00033   1 CPPPPVPENGTVTGSKGS--YSYGSTVTYSCNEGYtLVGSSTITCTENGGWSPPPPTCE 57
CCP smart00032
Domain abundant in complement control proteins; SUSHI repeat; short complement-like repeat ...
 42-98 1.63e-04

Domain abundant in complement control proteins; SUSHI repeat; short complement-like repeat (SCR); The complement control protein (CCP) modules (also known as short consensus repeats SCRs or SUSHI repeats) contain approximately 60 amino acid residues and have been identified in several proteins of the complement system. A missense mutation in seventh CCP domain causes deficiency of the b subunit of factor XIII.


Pssm-ID: 214478 [Multi-domain]  Cd Length: 56  Bit Score: 39.43  E-value: 1.63e-04
                           10        20        30        40        50
                   ....*....|....*....|....*....|....*....|....*....|....*...
gi 52426750     42 CPAPSQLPSAKPINLTDEsmFPIGTYLLYECLPGY-IKRQFSITCKQDSTWTSAEDKC 98
Cdd:smart00032   1 CPPPPDIENGTVTSSSGT--YSYGDTVTYSCDPGYtLIGSSTITCLENGTWSPPPPTC 56
PHA02817 PHA02817
EEV Host range protein; Provisional
 83-160 1.24e-03

EEV Host range protein; Provisional


Pssm-ID: 165167 [Multi-domain]  Cd Length: 225  Bit Score: 40.31  E-value: 1.24e-03
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 52426750   83 ITCKQDSTWTSAEDKCIRKQCKTPSdPENGLVHvhtGIQ------FGSRINYTCNQGYRLIGSSSAVCVITDQsvdWDTE 156
Cdd:PHA02817  69 IICEKDGKWNKEFPVCKIIRCRFPA-LQNGFVN---GIPdskkfyYESEVSFSCKPGFVLIGTKYSVCGINSS---WIPK 141


                 ....
gi 52426750  157 APIC 160
Cdd:PHA02817 142 VPIC 145
PHA02954 PHA02954
EEV membrane glycoprotein; Provisional
 82-240 2.71e-03

EEV membrane glycoprotein; Provisional


Pssm-ID: 165263 [Multi-domain]  Cd Length: 317  Bit Score: 39.68  E-value: 2.71e-03
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 52426750   82 SITCKQDSTWTSAEDK-----------CIRKQCKTPSDPENGLVHVHTGIQFGSRINYTCNQGYRLIGSSSAVCVITDQS 150
Cdd:PHA02954  98 TLICKDETKYFRCEEKngntswndtvtCPNAECQPLQLEHGSCQPVKEKYSFGEHITINCDVGYEVIGASYISCTANSWN 177

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 52426750  151 VdwdteAPICEWiPCEIpPGIPNGDFFSSTredFHYGMVVTYRCntdargKALFNLVGEPSLYCTSndgeiGVWSGPPPQ 230
Cdd:PHA02954 178 V-----IPSCQQ-KCDI-PSLSNGLISGST---FSIGGVIHLSC------KSGFTLTGSPSSTCID-----GKWNPVLPI 236

                        170
                 ....*....|
gi 52426750  231 CIELNKCTPP 240
Cdd:PHA02954 237 CVRSNEEFDP 246
PHA02954 PHA02954
EEV membrane glycoprotein; Provisional
 181-295 5.30e-03

EEV membrane glycoprotein; Provisional


Pssm-ID: 165263 [Multi-domain]  Cd Length: 317  Bit Score: 38.91  E-value: 5.30e-03
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 52426750  181 REDFHYGMVVTYRCNTDargkalFNLVGEPSLYCTSNDGEIgvwsgpPPQCIElnKCTPPPYVENAVmlseNRSLFSLRD 260
Cdd:PHA02954 144 KEKYSFGEHITINCDVG------YEVIGASYISCTANSWNV------IPSCQQ--KCDIPSLSNGLI----SGSTFSIGG 205

                         90       100       110
                 ....*....|....*....|....*....|....*
gi 52426750  261 IVEFRCHPGFIMKGASSVHCQSlNKWEPELPSCFK 295
Cdd:PHA02954 206 VIHLSCKSGFTLTGSPSSTCID-GKWNPVLPICVR 239
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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