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Conserved domains on  [gi|17505581|ref|NP_492090|]
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Cuticle collagen 7 [Caenorhabditis elegans]

Protein Classification

cuticular collagen family protein( domain architecture ID 18387949)

cuticular collagen family protein is a structural macromolecule of the extracellular matrix containing triple helix domains that form tight interactions and stabilize supramolecular aggregates

Gene Ontology:  GO:0042302|GO:0005581
PubMed:  1916105|21421911

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
Col_cuticle_N smart01088
Nematode cuticle collagen N-terminal domain; The function of this domain is unknown. It is ...
 5-57 1.79e-15

Nematode cuticle collagen N-terminal domain; The function of this domain is unknown. It is found in the N-terminal region of nematode cuticle collagens. Cuticle is a tough elastic structure secreted by hypodermal cells and is primarily composed of collagen proteins.


:

Pssm-ID: 198156  Cd Length: 53  Bit Score: 69.42  E-value: 1.79e-15
                           10        20        30        40        50
                   ....*....|....*....|....*....|....*....|....*....|...
gi 17505581      5 TFLSVMAGLSGIVVFGALISVFHIYSDINSFVEDSHRELGEFKGFANDAWNSM 57
Cdd:smart01088   1 LVAYVAVAVSTVAVLSALVTLPSIYNDIQSFQSELLDEMDEFKARADDAWNEM 53
gly_rich_SclB super family cl45768
LPXTG-anchored collagen-like adhesin Scl2/SclB; SclB (or Scl2 - streptococcal collagen-like ...
 103-266 3.97e-09

LPXTG-anchored collagen-like adhesin Scl2/SclB; SclB (or Scl2 - streptococcal collagen-like protein 2) is an LPXTG-anchored surface-anchored adhesin with a variable-length region of triple helix-forming collagen-like Gly-Xaa-Xaa repeats.


The actual alignment was detected with superfamily member NF038329:

Pssm-ID: 468478 [Multi-domain]  Cd Length: 440  Bit Score: 57.22  E-value: 3.97e-09
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17505581  103 GDKGHDGQPGQAGKPGQPGVAGPSHHQKQECIKCPQGLPGPAGVPGQPGPKGPNGNPGAPAQGGGQGPPGPPGPAGSAGS 182
Cdd:NF038329 138 GDRGETGPAGPAGPPGPQGERGEKGPAGPQGEAGPQGPAGKDGEAGAKGPAGEKGPQGPRGETGPAGEQGPAGPAGPDGE 217

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17505581  183 PGQAGAPGNPGSPGKSGQRGRGLPGPSGAPGPQGPPGAPGQPGSGNAPGPAGPPGPAGPNGQPGHPGQDGQPGAPGNDGT 262
Cdd:NF038329 218 AGPAGEDGPAGPAGDGQQGPDGDPGPTGEDGPQGPDGPAGKDGPRGDRGEAGPDGPDGKDGERGPVGPAGKDGQNGKDGL 297


                 ....
gi 17505581  263 PGSD 266
Cdd:NF038329 298 PGKD 301
 
Name Accession Description Interval E-value
Col_cuticle_N smart01088
Nematode cuticle collagen N-terminal domain; The function of this domain is unknown. It is ...
 5-57 1.79e-15

Nematode cuticle collagen N-terminal domain; The function of this domain is unknown. It is found in the N-terminal region of nematode cuticle collagens. Cuticle is a tough elastic structure secreted by hypodermal cells and is primarily composed of collagen proteins.


Pssm-ID: 198156  Cd Length: 53  Bit Score: 69.42  E-value: 1.79e-15
                           10        20        30        40        50
                   ....*....|....*....|....*....|....*....|....*....|...
gi 17505581      5 TFLSVMAGLSGIVVFGALISVFHIYSDINSFVEDSHRELGEFKGFANDAWNSM 57
Cdd:smart01088   1 LVAYVAVAVSTVAVLSALVTLPSIYNDIQSFQSELLDEMDEFKARADDAWNEM 53
Col_cuticle_N pfam01484
Nematode cuticle collagen N-terminal domain; The function of this domain is unknown. It is ...
 9-57 3.56e-13

Nematode cuticle collagen N-terminal domain; The function of this domain is unknown. It is found in the N-terminal region of nematode cuticle collagens, see pfam01391. Cuticle is a tough elastic structure secreted by hypodermal cells and is primarily composed of collagen proteins.


Pssm-ID: 460226  Cd Length: 50  Bit Score: 62.86  E-value: 3.56e-13
                          10        20        30        40
                  ....*....|....*....|....*....|....*....|....*....
gi 17505581     9 VMAGLSGIVVFGALISVFHIYSDINSFVEDSHRELGEFKGFANDAWNSM 57
Cdd:pfam01484   2 VAVAFSTVAILSSLITLPSIYNDIQELQSEVLDEMDEFKARSDDAWNEM 50
gly_rich_SclB NF038329
LPXTG-anchored collagen-like adhesin Scl2/SclB; SclB (or Scl2 - streptococcal collagen-like ...
 103-266 3.97e-09

LPXTG-anchored collagen-like adhesin Scl2/SclB; SclB (or Scl2 - streptococcal collagen-like protein 2) is an LPXTG-anchored surface-anchored adhesin with a variable-length region of triple helix-forming collagen-like Gly-Xaa-Xaa repeats.


Pssm-ID: 468478 [Multi-domain]  Cd Length: 440  Bit Score: 57.22  E-value: 3.97e-09
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17505581  103 GDKGHDGQPGQAGKPGQPGVAGPSHHQKQECIKCPQGLPGPAGVPGQPGPKGPNGNPGAPAQGGGQGPPGPPGPAGSAGS 182
Cdd:NF038329 138 GDRGETGPAGPAGPPGPQGERGEKGPAGPQGEAGPQGPAGKDGEAGAKGPAGEKGPQGPRGETGPAGEQGPAGPAGPDGE 217

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17505581  183 PGQAGAPGNPGSPGKSGQRGRGLPGPSGAPGPQGPPGAPGQPGSGNAPGPAGPPGPAGPNGQPGHPGQDGQPGAPGNDGT 262
Cdd:NF038329 218 AGPAGEDGPAGPAGDGQQGPDGDPGPTGEDGPQGPDGPAGKDGPRGDRGEAGPDGPDGKDGERGPVGPAGKDGQNGKDGL 297


                 ....
gi 17505581  263 PGSD 266
Cdd:NF038329 298 PGKD 301
gly_rich_SclB NF038329
LPXTG-anchored collagen-like adhesin Scl2/SclB; SclB (or Scl2 - streptococcal collagen-like ...
 103-266 6.60e-06

LPXTG-anchored collagen-like adhesin Scl2/SclB; SclB (or Scl2 - streptococcal collagen-like protein 2) is an LPXTG-anchored surface-anchored adhesin with a variable-length region of triple helix-forming collagen-like Gly-Xaa-Xaa repeats.


Pssm-ID: 468478 [Multi-domain]  Cd Length: 440  Bit Score: 47.21  E-value: 6.60e-06
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17505581  103 GDKGHDGQPGQAGKPGQPGVAGPSHHQKQECIKCPQGLPGPAGVPGQPGPKGPNGnPGAPAQGGGQGPPGPPGPAGSAGS 182
Cdd:NF038329 153 GPQGERGEKGPAGPQGEAGPQGPAGKDGEAGAKGPAGEKGPQGPRGETGPAGEQG-PAGPAGPDGEAGPAGEDGPAGPAG 231

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17505581  183 PGQAGAPGNPGSPGKSGQRG-RGLPGPSGAPGPQGPPGAPGQPGSGNAPGPAGPPGPAGPNGQPGHP------------- 248
Cdd:NF038329 232 DGQQGPDGDPGPTGEDGPQGpDGPAGKDGPRGDRGEAGPDGPDGKDGERGPVGPAGKDGQNGKDGLPgkdgkdgqngkdg 311

                        170       180
                 ....*....|....*....|...
gi 17505581  249 -----GQDGQPGAPGNDGTPGSD 266
Cdd:NF038329 312 lpgkdGKDGQPGKDGLPGKDGKD 334
gly_rich_SclB NF038329
LPXTG-anchored collagen-like adhesin Scl2/SclB; SclB (or Scl2 - streptococcal collagen-like ...
 103-257 1.58e-03

LPXTG-anchored collagen-like adhesin Scl2/SclB; SclB (or Scl2 - streptococcal collagen-like protein 2) is an LPXTG-anchored surface-anchored adhesin with a variable-length region of triple helix-forming collagen-like Gly-Xaa-Xaa repeats.


Pssm-ID: 468478 [Multi-domain]  Cd Length: 440  Bit Score: 39.89  E-value: 1.58e-03
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17505581  103 GDKGHDGQPGQAGKPGQPGVAGPSHHQKQECIKCPQGLPGPAGVP-----GQPGPKGPNGNPGAPAQGGGQGPPGPPGPA 177
Cdd:NF038329 189 GEKGPQGPRGETGPAGEQGPAGPAGPDGEAGPAGEDGPAGPAGDGqqgpdGDPGPTGEDGPQGPDGPAGKDGPRGDRGEA 268

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17505581  178 GSAGSPGQAGAPGNPGSPGKSGQRG-RGLPGPSGAPGPQGPPGAPGQPGSGNAPGPAGPPGPAGPngqpghpgqDGQPGA 256
Cdd:NF038329 269 GPDGPDGKDGERGPVGPAGKDGQNGkDGLPGKDGKDGQNGKDGLPGKDGKDGQPGKDGLPGKDGK---------DGQPGK 339


                 .
gi 17505581  257 P 257
Cdd:NF038329 340 P 340
 
Name Accession Description Interval E-value
Col_cuticle_N smart01088
Nematode cuticle collagen N-terminal domain; The function of this domain is unknown. It is ...
 5-57 1.79e-15

Nematode cuticle collagen N-terminal domain; The function of this domain is unknown. It is found in the N-terminal region of nematode cuticle collagens. Cuticle is a tough elastic structure secreted by hypodermal cells and is primarily composed of collagen proteins.


Pssm-ID: 198156  Cd Length: 53  Bit Score: 69.42  E-value: 1.79e-15
                           10        20        30        40        50
                   ....*....|....*....|....*....|....*....|....*....|...
gi 17505581      5 TFLSVMAGLSGIVVFGALISVFHIYSDINSFVEDSHRELGEFKGFANDAWNSM 57
Cdd:smart01088   1 LVAYVAVAVSTVAVLSALVTLPSIYNDIQSFQSELLDEMDEFKARADDAWNEM 53
Col_cuticle_N pfam01484
Nematode cuticle collagen N-terminal domain; The function of this domain is unknown. It is ...
 9-57 3.56e-13

Nematode cuticle collagen N-terminal domain; The function of this domain is unknown. It is found in the N-terminal region of nematode cuticle collagens, see pfam01391. Cuticle is a tough elastic structure secreted by hypodermal cells and is primarily composed of collagen proteins.


Pssm-ID: 460226  Cd Length: 50  Bit Score: 62.86  E-value: 3.56e-13
                          10        20        30        40
                  ....*....|....*....|....*....|....*....|....*....
gi 17505581     9 VMAGLSGIVVFGALISVFHIYSDINSFVEDSHRELGEFKGFANDAWNSM 57
Cdd:pfam01484   2 VAVAFSTVAILSSLITLPSIYNDIQELQSEVLDEMDEFKARSDDAWNEM 50
gly_rich_SclB NF038329
LPXTG-anchored collagen-like adhesin Scl2/SclB; SclB (or Scl2 - streptococcal collagen-like ...
 103-266 3.97e-09

LPXTG-anchored collagen-like adhesin Scl2/SclB; SclB (or Scl2 - streptococcal collagen-like protein 2) is an LPXTG-anchored surface-anchored adhesin with a variable-length region of triple helix-forming collagen-like Gly-Xaa-Xaa repeats.


Pssm-ID: 468478 [Multi-domain]  Cd Length: 440  Bit Score: 57.22  E-value: 3.97e-09
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17505581  103 GDKGHDGQPGQAGKPGQPGVAGPSHHQKQECIKCPQGLPGPAGVPGQPGPKGPNGNPGAPAQGGGQGPPGPPGPAGSAGS 182
Cdd:NF038329 138 GDRGETGPAGPAGPPGPQGERGEKGPAGPQGEAGPQGPAGKDGEAGAKGPAGEKGPQGPRGETGPAGEQGPAGPAGPDGE 217

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17505581  183 PGQAGAPGNPGSPGKSGQRGRGLPGPSGAPGPQGPPGAPGQPGSGNAPGPAGPPGPAGPNGQPGHPGQDGQPGAPGNDGT 262
Cdd:NF038329 218 AGPAGEDGPAGPAGDGQQGPDGDPGPTGEDGPQGPDGPAGKDGPRGDRGEAGPDGPDGKDGERGPVGPAGKDGQNGKDGL 297


                 ....
gi 17505581  263 PGSD 266
Cdd:NF038329 298 PGKD 301
gly_rich_SclB NF038329
LPXTG-anchored collagen-like adhesin Scl2/SclB; SclB (or Scl2 - streptococcal collagen-like ...
 103-266 6.60e-06

LPXTG-anchored collagen-like adhesin Scl2/SclB; SclB (or Scl2 - streptococcal collagen-like protein 2) is an LPXTG-anchored surface-anchored adhesin with a variable-length region of triple helix-forming collagen-like Gly-Xaa-Xaa repeats.


Pssm-ID: 468478 [Multi-domain]  Cd Length: 440  Bit Score: 47.21  E-value: 6.60e-06
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17505581  103 GDKGHDGQPGQAGKPGQPGVAGPSHHQKQECIKCPQGLPGPAGVPGQPGPKGPNGnPGAPAQGGGQGPPGPPGPAGSAGS 182
Cdd:NF038329 153 GPQGERGEKGPAGPQGEAGPQGPAGKDGEAGAKGPAGEKGPQGPRGETGPAGEQG-PAGPAGPDGEAGPAGEDGPAGPAG 231

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17505581  183 PGQAGAPGNPGSPGKSGQRG-RGLPGPSGAPGPQGPPGAPGQPGSGNAPGPAGPPGPAGPNGQPGHP------------- 248
Cdd:NF038329 232 DGQQGPDGDPGPTGEDGPQGpDGPAGKDGPRGDRGEAGPDGPDGKDGERGPVGPAGKDGQNGKDGLPgkdgkdgqngkdg 311

                        170       180
                 ....*....|....*....|...
gi 17505581  249 -----GQDGQPGAPGNDGTPGSD 266
Cdd:NF038329 312 lpgkdGKDGQPGKDGLPGKDGKD 334
gly_rich_SclB NF038329
LPXTG-anchored collagen-like adhesin Scl2/SclB; SclB (or Scl2 - streptococcal collagen-like ...
 103-257 1.58e-03

LPXTG-anchored collagen-like adhesin Scl2/SclB; SclB (or Scl2 - streptococcal collagen-like protein 2) is an LPXTG-anchored surface-anchored adhesin with a variable-length region of triple helix-forming collagen-like Gly-Xaa-Xaa repeats.


Pssm-ID: 468478 [Multi-domain]  Cd Length: 440  Bit Score: 39.89  E-value: 1.58e-03
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17505581  103 GDKGHDGQPGQAGKPGQPGVAGPSHHQKQECIKCPQGLPGPAGVP-----GQPGPKGPNGNPGAPAQGGGQGPPGPPGPA 177
Cdd:NF038329 189 GEKGPQGPRGETGPAGEQGPAGPAGPDGEAGPAGEDGPAGPAGDGqqgpdGDPGPTGEDGPQGPDGPAGKDGPRGDRGEA 268

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17505581  178 GSAGSPGQAGAPGNPGSPGKSGQRG-RGLPGPSGAPGPQGPPGAPGQPGSGNAPGPAGPPGPAGPngqpghpgqDGQPGA 256
Cdd:NF038329 269 GPDGPDGKDGERGPVGPAGKDGQNGkDGLPGKDGKDGQNGKDGLPGKDGKDGQPGKDGLPGKDGK---------DGQPGK 339


                 .
gi 17505581  257 P 257
Cdd:NF038329 340 P 340
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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