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Conserved domains on  [gi|17563356|ref|NP_503204|]
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Serpentine Receptor, class H [Caenorhabditis elegans]

Protein Classification

serpentine receptor domain-containing protein( domain architecture ID 27798)

serpentine receptor domain-containing protein which belongs to a family of seven-transmembrane (7TM) G protein-coupled receptors involved in chemoreception, a central sense of soil nematodes like Caenorhabditis elegans

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
7TM_GPCR_Srh super family cl11665
Serpentine type 7TM GPCR chemoreceptor Srh; Chemoreception is mediated in Caenorhabditis ...
 10-317 3.95e-13

Serpentine type 7TM GPCR chemoreceptor Srh; Chemoreception is mediated in Caenorhabditis elegans by members of the seven-transmembrane G-protein-coupled receptor class (7TM GPCRs) of proteins which are of the serpentine type. Srh is part of the Str superfamily of chemoreceptors. Chemoperception is one of the central senses of soil nematodes like C. elegans which are otherwise 'blind' and 'deaf'.


The actual alignment was detected with superfamily member pfam10318:

Pssm-ID: 416353  Cd Length: 302  Bit Score: 68.72  E-value: 3.95e-13
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17563356    10 ENPIFYNTIKRVFAFSIAIIFPFTHYCVLTKSPKSFGFLKW-IIYFHCCCVTCEWLNNAFLIDIMTFqPSVLIRVDGFLN 88
Cdd:pfam10318   1 ASPDFLSTSLHIITVISIPIHIFGFYCILFKTPKKMKSVKWsLLNLHFWSALLDLSLSFLTIPYIFL-PALAGYPLGLLS 79

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17563356    89 SL-IDPAVLFLISSCTEDLARTSALLLFTSRLFMIF-NMYRSNFSWTRYFGEGLVYTLVAVIglwTIPmTFWCLPDQytE 166
Cdd:pfam10318  80 YLgVPTPIQFYIGVTSLALVGVSIILLFENRYSILFtNKKRITWKKTRVLYLIFNYIIALLF---LIP-IYLNIPDQ--E 153

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17563356   167 KFRIVYNAKF--YPDGLWDST-VVVTSgsdLESERFVSIITILNSIIVG-ILIFASSkaAFYFLEKRMEVeNESEATRRM 242
Cdd:pfam10318 154 AAKLKVLKKLpcLPPEFFDNPpVFVLA---IDSTYFLICIVLLILILIIqILFFVFL--TIYYLFKSVKS-SLSKKTRKL 227

                         250       260       270       280       290       300       310
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 17563356   243 HQKFNQRTIFQAILYLSFMCIPISMLYLTILLDVKIKGLTYFIDFSIENHPVACIISLFLYYDPYQNYLLKVVRY 317
Cdd:pfam10318 228 QKKFFIALIIQVSIPLIVILIPLIYILFSIIFGYYNQALNNLLFIIISLHGLLSTIAMLLVHKPYRKFVLSLFKK 302
 
Name Accession Description Interval E-value
7TM_GPCR_Srh pfam10318
Serpentine type 7TM GPCR chemoreceptor Srh; Chemoreception is mediated in Caenorhabditis ...
 10-317 3.95e-13

Serpentine type 7TM GPCR chemoreceptor Srh; Chemoreception is mediated in Caenorhabditis elegans by members of the seven-transmembrane G-protein-coupled receptor class (7TM GPCRs) of proteins which are of the serpentine type. Srh is part of the Str superfamily of chemoreceptors. Chemoperception is one of the central senses of soil nematodes like C. elegans which are otherwise 'blind' and 'deaf'.


Pssm-ID: 402095  Cd Length: 302  Bit Score: 68.72  E-value: 3.95e-13
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17563356    10 ENPIFYNTIKRVFAFSIAIIFPFTHYCVLTKSPKSFGFLKW-IIYFHCCCVTCEWLNNAFLIDIMTFqPSVLIRVDGFLN 88
Cdd:pfam10318   1 ASPDFLSTSLHIITVISIPIHIFGFYCILFKTPKKMKSVKWsLLNLHFWSALLDLSLSFLTIPYIFL-PALAGYPLGLLS 79

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17563356    89 SL-IDPAVLFLISSCTEDLARTSALLLFTSRLFMIF-NMYRSNFSWTRYFGEGLVYTLVAVIglwTIPmTFWCLPDQytE 166
Cdd:pfam10318  80 YLgVPTPIQFYIGVTSLALVGVSIILLFENRYSILFtNKKRITWKKTRVLYLIFNYIIALLF---LIP-IYLNIPDQ--E 153

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17563356   167 KFRIVYNAKF--YPDGLWDST-VVVTSgsdLESERFVSIITILNSIIVG-ILIFASSkaAFYFLEKRMEVeNESEATRRM 242
Cdd:pfam10318 154 AAKLKVLKKLpcLPPEFFDNPpVFVLA---IDSTYFLICIVLLILILIIqILFFVFL--TIYYLFKSVKS-SLSKKTRKL 227

                         250       260       270       280       290       300       310
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 17563356   243 HQKFNQRTIFQAILYLSFMCIPISMLYLTILLDVKIKGLTYFIDFSIENHPVACIISLFLYYDPYQNYLLKVVRY 317
Cdd:pfam10318 228 QKKFFIALIIQVSIPLIVILIPLIYILFSIIFGYYNQALNNLLFIIISLHGLLSTIAMLLVHKPYRKFVLSLFKK 302
 
Name Accession Description Interval E-value
7TM_GPCR_Srh pfam10318
Serpentine type 7TM GPCR chemoreceptor Srh; Chemoreception is mediated in Caenorhabditis ...
 10-317 3.95e-13

Serpentine type 7TM GPCR chemoreceptor Srh; Chemoreception is mediated in Caenorhabditis elegans by members of the seven-transmembrane G-protein-coupled receptor class (7TM GPCRs) of proteins which are of the serpentine type. Srh is part of the Str superfamily of chemoreceptors. Chemoperception is one of the central senses of soil nematodes like C. elegans which are otherwise 'blind' and 'deaf'.


Pssm-ID: 402095  Cd Length: 302  Bit Score: 68.72  E-value: 3.95e-13
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17563356    10 ENPIFYNTIKRVFAFSIAIIFPFTHYCVLTKSPKSFGFLKW-IIYFHCCCVTCEWLNNAFLIDIMTFqPSVLIRVDGFLN 88
Cdd:pfam10318   1 ASPDFLSTSLHIITVISIPIHIFGFYCILFKTPKKMKSVKWsLLNLHFWSALLDLSLSFLTIPYIFL-PALAGYPLGLLS 79

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17563356    89 SL-IDPAVLFLISSCTEDLARTSALLLFTSRLFMIF-NMYRSNFSWTRYFGEGLVYTLVAVIglwTIPmTFWCLPDQytE 166
Cdd:pfam10318  80 YLgVPTPIQFYIGVTSLALVGVSIILLFENRYSILFtNKKRITWKKTRVLYLIFNYIIALLF---LIP-IYLNIPDQ--E 153

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17563356   167 KFRIVYNAKF--YPDGLWDST-VVVTSgsdLESERFVSIITILNSIIVG-ILIFASSkaAFYFLEKRMEVeNESEATRRM 242
Cdd:pfam10318 154 AAKLKVLKKLpcLPPEFFDNPpVFVLA---IDSTYFLICIVLLILILIIqILFFVFL--TIYYLFKSVKS-SLSKKTRKL 227

                         250       260       270       280       290       300       310
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 17563356   243 HQKFNQRTIFQAILYLSFMCIPISMLYLTILLDVKIKGLTYFIDFSIENHPVACIISLFLYYDPYQNYLLKVVRY 317
Cdd:pfam10318 228 QKKFFIALIIQVSIPLIVILIPLIYILFSIIFGYYNQALNNLLFIIISLHGLLSTIAMLLVHKPYRKFVLSLFKK 302
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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