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Conserved domains on  [gi|17563320|ref|NP_504303|]
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Serpentine receptor class delta-32 [Caenorhabditis elegans]

Protein Classification

class D serpentine receptor( domain architecture ID 10563389)

class D serpentine receptor (Srd) belongs to a family of seven-transmembrane (7TM) G protein-coupled receptors involved in chemoreception, a central sense of soil nematodes like Caenorhabditis elegans

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
7TM_GPCR_Srd pfam10317
Serpentine type 7TM GPCR chemoreceptor Srd; Chemoreception is mediated in Caenorhabditis ...
 10-299 1.36e-68

Serpentine type 7TM GPCR chemoreceptor Srd; Chemoreception is mediated in Caenorhabditis elegans by members of the seven-transmembrane G-protein-coupled receptor class (7TM GPCRs) of proteins which are of the serpentine type. Srd is part of the larger Str superfamily of chemoreceptors. Chemoperception is one of the central senses of soil nematodes like C. elegans which are otherwise 'blind' and 'deaf'.


:

Pssm-ID: 402094  Cd Length: 292  Bit Score: 216.26  E-value: 1.36e-68
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17563320    10 YISYAAVVSTLGIIFNGFLLFLIFFKSPSCLTPYTVFLANTSITQLGYCICFLLTVPRVISINLRIVNIYLGFSQFLGHW 89
Cdd:pfam10317   1 FSIYYPIFFILGLILNLLLLYLIIFKSPKSLKTYRILLLNTAITQIISCILAFFTQQRIIPNGVSMALISYGPCKYFGPW 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17563320    90 WSYMIFTTMLHFAVNSFLSIMLSMVFRCISLKTLRFPTSGAFAMCILAYMIPLSMvvsirGIEITSNFTINSKYTLWQLE 169
Cdd:pfam10317  81 FCYSGYSLLQHFLLHSGWSLLLTFYYRYYILKHVDPKRKKLILLIIIHYIPSLSQ-----LIVIFLSPTDFLPVEALTKE 155

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17563320   170 NLDKYR----TVVGTTMAQ-LSTLWVACCVSILCIPIYSVMFWCRYRILRMLERPGYMFNTTTTLQIKRLVKALTVQSLI 244
Cdd:pfam10317 156 LHPNYNltdyTVTGFSDLQsFPALINTLIMTIPVFPIPIIILILRRKILKLLNSNSVNMSPTTKAQHRQLIKGLTIQALL 235

                         250       260       270       280       290
                  ....*....|....*....|....*....|....*....|....*....|....*
gi 17563320   245 PVFTLFPASLIFLSTQFHVIETTKFGYIIISLLSLSPTIDPLVTIYYVQPYRKYI 299
Cdd:pfam10317 236 PLFSYIPGVTLYLLSQLTGTEFLILEYFIFVLPALPPLLDPLITIYFVTPYRRAI 290
 
Name Accession Description Interval E-value
7TM_GPCR_Srd pfam10317
Serpentine type 7TM GPCR chemoreceptor Srd; Chemoreception is mediated in Caenorhabditis ...
 10-299 1.36e-68

Serpentine type 7TM GPCR chemoreceptor Srd; Chemoreception is mediated in Caenorhabditis elegans by members of the seven-transmembrane G-protein-coupled receptor class (7TM GPCRs) of proteins which are of the serpentine type. Srd is part of the larger Str superfamily of chemoreceptors. Chemoperception is one of the central senses of soil nematodes like C. elegans which are otherwise 'blind' and 'deaf'.


Pssm-ID: 402094  Cd Length: 292  Bit Score: 216.26  E-value: 1.36e-68
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17563320    10 YISYAAVVSTLGIIFNGFLLFLIFFKSPSCLTPYTVFLANTSITQLGYCICFLLTVPRVISINLRIVNIYLGFSQFLGHW 89
Cdd:pfam10317   1 FSIYYPIFFILGLILNLLLLYLIIFKSPKSLKTYRILLLNTAITQIISCILAFFTQQRIIPNGVSMALISYGPCKYFGPW 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17563320    90 WSYMIFTTMLHFAVNSFLSIMLSMVFRCISLKTLRFPTSGAFAMCILAYMIPLSMvvsirGIEITSNFTINSKYTLWQLE 169
Cdd:pfam10317  81 FCYSGYSLLQHFLLHSGWSLLLTFYYRYYILKHVDPKRKKLILLIIIHYIPSLSQ-----LIVIFLSPTDFLPVEALTKE 155

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17563320   170 NLDKYR----TVVGTTMAQ-LSTLWVACCVSILCIPIYSVMFWCRYRILRMLERPGYMFNTTTTLQIKRLVKALTVQSLI 244
Cdd:pfam10317 156 LHPNYNltdyTVTGFSDLQsFPALINTLIMTIPVFPIPIIILILRRKILKLLNSNSVNMSPTTKAQHRQLIKGLTIQALL 235

                         250       260       270       280       290
                  ....*....|....*....|....*....|....*....|....*....|....*
gi 17563320   245 PVFTLFPASLIFLSTQFHVIETTKFGYIIISLLSLSPTIDPLVTIYYVQPYRKYI 299
Cdd:pfam10317 236 PLFSYIPGVTLYLLSQLTGTEFLILEYFIFVLPALPPLLDPLITIYFVTPYRRAI 290
 
Name Accession Description Interval E-value
7TM_GPCR_Srd pfam10317
Serpentine type 7TM GPCR chemoreceptor Srd; Chemoreception is mediated in Caenorhabditis ...
 10-299 1.36e-68

Serpentine type 7TM GPCR chemoreceptor Srd; Chemoreception is mediated in Caenorhabditis elegans by members of the seven-transmembrane G-protein-coupled receptor class (7TM GPCRs) of proteins which are of the serpentine type. Srd is part of the larger Str superfamily of chemoreceptors. Chemoperception is one of the central senses of soil nematodes like C. elegans which are otherwise 'blind' and 'deaf'.


Pssm-ID: 402094  Cd Length: 292  Bit Score: 216.26  E-value: 1.36e-68
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17563320    10 YISYAAVVSTLGIIFNGFLLFLIFFKSPSCLTPYTVFLANTSITQLGYCICFLLTVPRVISINLRIVNIYLGFSQFLGHW 89
Cdd:pfam10317   1 FSIYYPIFFILGLILNLLLLYLIIFKSPKSLKTYRILLLNTAITQIISCILAFFTQQRIIPNGVSMALISYGPCKYFGPW 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17563320    90 WSYMIFTTMLHFAVNSFLSIMLSMVFRCISLKTLRFPTSGAFAMCILAYMIPLSMvvsirGIEITSNFTINSKYTLWQLE 169
Cdd:pfam10317  81 FCYSGYSLLQHFLLHSGWSLLLTFYYRYYILKHVDPKRKKLILLIIIHYIPSLSQ-----LIVIFLSPTDFLPVEALTKE 155

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17563320   170 NLDKYR----TVVGTTMAQ-LSTLWVACCVSILCIPIYSVMFWCRYRILRMLERPGYMFNTTTTLQIKRLVKALTVQSLI 244
Cdd:pfam10317 156 LHPNYNltdyTVTGFSDLQsFPALINTLIMTIPVFPIPIIILILRRKILKLLNSNSVNMSPTTKAQHRQLIKGLTIQALL 235

                         250       260       270       280       290
                  ....*....|....*....|....*....|....*....|....*....|....*
gi 17563320   245 PVFTLFPASLIFLSTQFHVIETTKFGYIIISLLSLSPTIDPLVTIYYVQPYRKYI 299
Cdd:pfam10317 236 PLFSYIPGVTLYLLSQLTGTEFLILEYFIFVLPALPPLLDPLITIYFVTPYRRAI 290
7TM_GPCR_Str pfam10326
Serpentine type 7TM GPCR chemoreceptor Str; Chemoreception is mediated in Caenorhabditis ...
 10-299 9.75e-11

Serpentine type 7TM GPCR chemoreceptor Str; Chemoreception is mediated in Caenorhabditis elegans by members of the seven-transmembrane G-protein-coupled receptor class (7TM GPCRs) of proteins which are of the serpentine type. Str is a member of the Str superfamily of chemoreceptors. Almost a quarter (22.5%) of str and srj family genes and pseudogenes in C. elegans appear to have been newly formed by gene duplications since the species split. Chemoperception is one of the central senses of soil nematodes like C. elegans which are otherwise 'blind' and 'deaf'.


Pssm-ID: 402099  Cd Length: 307  Bit Score: 61.70  E-value: 9.75e-11
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17563320    10 YISYAAVVSTlgIIFNGFLLFLIFFKSPSCLTPYTVFLANTSITQLGYCICFLLTVPRVISINLRIVNIYLGFSQFLGHW 89
Cdd:pfam10326   3 IIQYIGFFLS--ILLNSILIYLILFKSPKIFGTYKYLMIYFSIFGIFFSILEFIVKPFIHSYNSSFIVFVDLKDLGLSKS 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17563320    90 WSYMIFTTMlhfavNSFLSIMLSM-----VFRCISL----KTLRFPTSGAFAMCILAYMIPLSMVVSIR-GIEITSNFTI 159
Cdd:pfam10326  81 VGQILLALY-----CGFYGVSISLlavqfIYRYLALcrpgKLKYFDGKKLILWFLYPLIFGAIWGLLVYfFLGPDEETDE 155

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17563320   160 NSKYTLWQLENLDKYRTVV-----------GTTMAQLSTLW-VACCVSILCIPiYSVMFWCRYRI-LRMLERPGYMFNTT 226
Cdd:pfam10326 156 YLREELLENYNLDIDEVAYvgpvyyptdenGSKVIRWRSLIgLLIMTFIIGIS-FSIIIYCGIKMyFKMKKLKSLGSEKT 234

                         250       260       270       280       290       300       310
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 17563320   227 TTLQiKRLVKALTVQSLIPVFTLF-PASLIFLSTQFHvIETTKFGYIIISLLSLSPTIDPLVTIYYVQPYRKYI 299
Cdd:pfam10326 235 RKLQ-KQLFKALVIQTLIPTILMYiPVGILFLLPLFN-IEIGFLSGIITATIALYPAIDPLPAMFIIKEYRNAI 306
7TM_GPCR_Srh pfam10318
Serpentine type 7TM GPCR chemoreceptor Srh; Chemoreception is mediated in Caenorhabditis ...
 16-304 4.75e-03

Serpentine type 7TM GPCR chemoreceptor Srh; Chemoreception is mediated in Caenorhabditis elegans by members of the seven-transmembrane G-protein-coupled receptor class (7TM GPCRs) of proteins which are of the serpentine type. Srh is part of the Str superfamily of chemoreceptors. Chemoperception is one of the central senses of soil nematodes like C. elegans which are otherwise 'blind' and 'deaf'.


Pssm-ID: 402095  Cd Length: 302  Bit Score: 38.29  E-value: 4.75e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17563320    16 VVSTLGIIFNGFLLFLIFFKSPSCLTPYTVFLAN--TSITQLGYCICFLLTVPRVISInlrIVNIYLGFSQFLGH---WW 90
Cdd:pfam10318  12 IITVISIPIHIFGFYCILFKTPKKMKSVKWSLLNlhFWSALLDLSLSFLTIPYIFLPA---LAGYPLGLLSYLGVptpIQ 88

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17563320    91 SYMIFTTMLHFAVnSFLSI------MLSMVFRCISLKTLRFPTsgAFAMCILAYMIPLSMVVSIRGIEITSNFTINsKYT 164
Cdd:pfam10318  89 FYIGVTSLALVGV-SIILLfenrysILFTNKKRITWKKTRVLY--LIFNYIIALLFLIPIYLNIPDQEAAKLKVLK-KLP 164

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17563320   165 LWQLENLDKYRTVVGTTMAQLSTLWVACCVSILCIPIYSVMFWCRYRILRMLERPgyMFNTTTTLQiKRLVKALTVQSLI 244
Cdd:pfam10318 165 CLPPEFFDNPPVFVLAIDSTYFLICIVLLILILIIQILFFVFLTIYYLFKSVKSS--LSKKTRKLQ-KKFFIALIIQVSI 241

                         250       260       270       280       290       300
                  ....*....|....*....|....*....|....*....|....*....|....*....|...
gi 17563320   245 P-VFTLFPASLIFLS--TQFHVIETTKFGYIIISLLSLSPTIdplVTIYYVQPYRKYIVDLLW 304
Cdd:pfam10318 242 PlIVILIPLIYILFSiiFGYYNQALNNLLFIIISLHGLLSTI---AMLLVHKPYRKFVLSLFK 301
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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