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Conserved domains on  [gi|1254049779|ref|NP_506607|]
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Kelch-like protein 10 [Caenorhabditis elegans]

Protein Classification

Kelch repeat-containing protein( domain architecture ID 11459646)

Kelch repeat-containing protein, member of a superfamily of proteins with diverse functions

CATH:  2.120.10.80
Gene Ontology:  GO:0005515
PubMed:  10603472|31442578|24959344
SCOP:  3000448

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
NanM COG3055
N-acetylneuraminic acid mutarotase [Cell wall/membrane/envelope biogenesis];
136-360 1.14e-30

N-acetylneuraminic acid mutarotase [Cell wall/membrane/envelope biogenesis];


:

Pssm-ID: 442289 [Multi-domain]  Cd Length: 277  Bit Score: 118.33  E-value: 1.14e-30
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1254049779 136 FKPDTMSFMPIGRLP-NPKSHYAVVSSSTKVFIIGGMN----NGTYLNRVEMFDKEKGIRVECTRLMHGRTRTSACIHED 210
Cdd:COG3055    43 YDPATNTWSELAPLPgPPRHHAAAVAQDGKLYVFGGFTganpSSTPLNDVYVYDPATNTWTKLAPMPTPRGGATALLLDG 122

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1254049779 211 AIYAVGGYD-ATYMSSVEIYDIKTGGdWTTGPSLNNRRADASVVSFY-GQLFVLGGFNGkdyeetieklSDSKDKFEVCG 288
Cdd:COG3055   123 KIYVVGGWDdGGNVAWVEVYDPATGT-WTQLAPLPTPRDHLAAAVLPdGKILVIGGRNG----------SGFSNTWTTLA 191

                         170       180       190       200       210       220       230
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 1254049779 289 NM-VGRAGFGACVFRGRIYVAGGWNtpcNTLKTFQSYDPLTNTWKDEPSMNTGRKYFKLHATNEAIYAIRGCS 360
Cdd:COG3055   192 PLpTARAGHAAAVLGGKILVFGGES---GFSDEVEAYDPATNTWTALGELPTPRHGHAAVLTDGKVYVIGGET 261
 
Name Accession Description Interval E-value
NanM COG3055
N-acetylneuraminic acid mutarotase [Cell wall/membrane/envelope biogenesis];
136-360 1.14e-30

N-acetylneuraminic acid mutarotase [Cell wall/membrane/envelope biogenesis];


Pssm-ID: 442289 [Multi-domain]  Cd Length: 277  Bit Score: 118.33  E-value: 1.14e-30
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1254049779 136 FKPDTMSFMPIGRLP-NPKSHYAVVSSSTKVFIIGGMN----NGTYLNRVEMFDKEKGIRVECTRLMHGRTRTSACIHED 210
Cdd:COG3055    43 YDPATNTWSELAPLPgPPRHHAAAVAQDGKLYVFGGFTganpSSTPLNDVYVYDPATNTWTKLAPMPTPRGGATALLLDG 122

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1254049779 211 AIYAVGGYD-ATYMSSVEIYDIKTGGdWTTGPSLNNRRADASVVSFY-GQLFVLGGFNGkdyeetieklSDSKDKFEVCG 288
Cdd:COG3055   123 KIYVVGGWDdGGNVAWVEVYDPATGT-WTQLAPLPTPRDHLAAAVLPdGKILVIGGRNG----------SGFSNTWTTLA 191

                         170       180       190       200       210       220       230
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 1254049779 289 NM-VGRAGFGACVFRGRIYVAGGWNtpcNTLKTFQSYDPLTNTWKDEPSMNTGRKYFKLHATNEAIYAIRGCS 360
Cdd:COG3055   192 PLpTARAGHAAAVLGGKILVFGGES---GFSDEVEAYDPATNTWTALGELPTPRHGHAAVLTDGKVYVIGGET 261
PHA03098 PHA03098
kelch-like protein; Provisional
 165-379 7.73e-18

kelch-like protein; Provisional


Pssm-ID: 222983 [Multi-domain]  Cd Length: 534  Bit Score: 84.82  E-value: 7.73e-18
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1254049779 165 VFIIGGMNNGTY-LNRVEMFDKEKGIRVECTRLMHGRTRTSACIHEDAIYAVGG-YDATYMSSVEIYDIKTGgDWTTGPS 242
Cdd:PHA03098  297 IYFIGGMNKNNLsVNSVVSYDTKTKSWNKVPELIYPRKNPGVTVFNNRIYVIGGiYNSISLNTVESWKPGES-KWREEPP 375

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1254049779 243 LNNRRADASVVSFYGQLFVLGGFNGKDYE-ETIEKLSDSKDKFEVCGNM-VGRAGFGACVFRGRIYVAGGWN--TPCNTL 318
Cdd:PHA03098  376 LIFPRYNPCVVNVNNLIYVIGGISKNDELlKTVECFSLNTNKWSKGSPLpISHYGGCAIYHDGKIYVIGGISyiDNIKVY 455

                         170       180       190       200       210       220
                  ....*....|....*....|....*....|....*....|....*....|....*....|.
gi 1254049779 319 KTFQSYDPLTNTWKDEPSMNTGRKYFKLHATNEAIYAIRGCSHDWdLIKETERFDPQTLTW 379
Cdd:PHA03098  456 NIVESYNPVTNKWTELSSLNFPRINASLCIFNNKIYVVGGDKYEY-YINEIEVYDDKTNTW 515
Kelch smart00612
Kelch domain;
304-351 6.78e-12

Kelch domain;


Pssm-ID: 128874 [Multi-domain]  Cd Length: 47  Bit Score: 59.88  E-value: 6.78e-12
                           10        20        30        40
                   ....*....|....*....|....*....|....*....|....*...
gi 1254049779  304 RIYVAGGWNtPCNTLKTFQSYDPLTNTWKDEPSMNTGRKYFKLHATNE 351
Cdd:smart00612   1 KIYVVGGFD-GGQRLKSVEVYDPETNKWTPLPSMPTPRSGHGVAVING 47
Kelch_1 pfam01344
Kelch motif; The kelch motif was initially discovered in Kelch. In this protein there are six ...
 293-338 6.10e-11

Kelch motif; The kelch motif was initially discovered in Kelch. In this protein there are six copies of the motif. It has been shown that Swiss:Q04652 is related to Galactose Oxidase for which a structure has been solved. The kelch motif forms a beta sheet. Several of these sheets associate to form a beta propeller structure as found in pfam00064, pfam00400 and pfam00415.


Pssm-ID: 396078 [Multi-domain]  Cd Length: 46  Bit Score: 56.85  E-value: 6.10e-11
                          10        20        30        40
                  ....*....|....*....|....*....|....*....|....*.
gi 1254049779 293 RAGFGACVFRGRIYVAGGWNtPCNTLKTFQSYDPLTNTWKDEPSMN 338
Cdd:pfam01344   2 RSGAGVVVVGGKIYVIGGFD-GNQSLNSVEVYDPETNTWSKLPSMP 46
 
Name Accession Description Interval E-value
NanM COG3055
N-acetylneuraminic acid mutarotase [Cell wall/membrane/envelope biogenesis];
136-360 1.14e-30

N-acetylneuraminic acid mutarotase [Cell wall/membrane/envelope biogenesis];


Pssm-ID: 442289 [Multi-domain]  Cd Length: 277  Bit Score: 118.33  E-value: 1.14e-30
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1254049779 136 FKPDTMSFMPIGRLP-NPKSHYAVVSSSTKVFIIGGMN----NGTYLNRVEMFDKEKGIRVECTRLMHGRTRTSACIHED 210
Cdd:COG3055    43 YDPATNTWSELAPLPgPPRHHAAAVAQDGKLYVFGGFTganpSSTPLNDVYVYDPATNTWTKLAPMPTPRGGATALLLDG 122

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1254049779 211 AIYAVGGYD-ATYMSSVEIYDIKTGGdWTTGPSLNNRRADASVVSFY-GQLFVLGGFNGkdyeetieklSDSKDKFEVCG 288
Cdd:COG3055   123 KIYVVGGWDdGGNVAWVEVYDPATGT-WTQLAPLPTPRDHLAAAVLPdGKILVIGGRNG----------SGFSNTWTTLA 191

                         170       180       190       200       210       220       230
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 1254049779 289 NM-VGRAGFGACVFRGRIYVAGGWNtpcNTLKTFQSYDPLTNTWKDEPSMNTGRKYFKLHATNEAIYAIRGCS 360
Cdd:COG3055   192 PLpTARAGHAAAVLGGKILVFGGES---GFSDEVEAYDPATNTWTALGELPTPRHGHAAVLTDGKVYVIGGET 261
NanM COG3055
N-acetylneuraminic acid mutarotase [Cell wall/membrane/envelope biogenesis];
149-379 3.36e-30

N-acetylneuraminic acid mutarotase [Cell wall/membrane/envelope biogenesis];


Pssm-ID: 442289 [Multi-domain]  Cd Length: 277  Bit Score: 116.79  E-value: 3.36e-30
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1254049779 149 LPNPKSHYAVVSSSTKVFIIGGMNNGTYLNRVEMFDKEKGirvECTRL----MHGRTRTSACIHEDAIYAVGGYDA---- 220
Cdd:COG3055     9 LPTPRSEAAAALLDGKVYVAGGLSGGSASNSFEVYDPATN---TWSELaplpGPPRHHAAAVAQDGKLYVFGGFTGanps 85

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1254049779 221 -TYMSSVEIYDIKTgGDWTTGPSLNNRRADASVVSFYGQLFVLGGFNGKDYEETIEKLSDSKDKFEVCGNMVG-RAGF-G 297
Cdd:COG3055    86 sTPLNDVYVYDPAT-NTWTKLAPMPTPRGGATALLLDGKIYVVGGWDDGGNVAWVEVYDPATGTWTQLAPLPTpRDHLaA 164

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1254049779 298 ACVFRGRIYVAGGWNtpcntlktfqsYDPLTNTWKDEPSMNTGRKYFKLHATNEAIYAIRGcshDWDLIKETERFDPQTL 377
Cdd:COG3055   165 AVLPDGKILVIGGRN-----------GSGFSNTWTTLAPLPTARAGHAAAVLGGKILVFGG---ESGFSDEVEAYDPATN 230


                  ..
gi 1254049779 378 TW 379
Cdd:COG3055   231 TW 232
NanM COG3055
N-acetylneuraminic acid mutarotase [Cell wall/membrane/envelope biogenesis];
235-379 7.54e-20

N-acetylneuraminic acid mutarotase [Cell wall/membrane/envelope biogenesis];


Pssm-ID: 442289 [Multi-domain]  Cd Length: 277  Bit Score: 88.29  E-value: 7.54e-20
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1254049779 235 GDWTTGPSLNNRRADASVVSFYGQLFVLGGFNGKDYEETIEKLSDSKDKFEVCGNM--VGRAGFGACVFRGRIYVAGGWN 312
Cdd:COG3055     1 ATWSSLPDLPTPRSEAAAALLDGKVYVAGGLSGGSASNSFEVYDPATNTWSELAPLpgPPRHHAAAVAQDGKLYVFGGFT 80

                          90       100       110       120       130       140       150
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1254049779 313 TPCNT---LKTFQSYDPLTNTWKDEPSMNTGRKYFKLHATNEAIYAIRGcSHDWDLIKETERFDPQTLTW 379
Cdd:COG3055    81 GANPSstpLNDVYVYDPATNTWTKLAPMPTPRGGATALLLDGKIYVVGG-WDDGGNVAWVEVYDPATGTW 149
PHA03098 PHA03098
kelch-like protein; Provisional
 165-379 7.73e-18

kelch-like protein; Provisional


Pssm-ID: 222983 [Multi-domain]  Cd Length: 534  Bit Score: 84.82  E-value: 7.73e-18
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1254049779 165 VFIIGGMNNGTY-LNRVEMFDKEKGIRVECTRLMHGRTRTSACIHEDAIYAVGG-YDATYMSSVEIYDIKTGgDWTTGPS 242
Cdd:PHA03098  297 IYFIGGMNKNNLsVNSVVSYDTKTKSWNKVPELIYPRKNPGVTVFNNRIYVIGGiYNSISLNTVESWKPGES-KWREEPP 375

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1254049779 243 LNNRRADASVVSFYGQLFVLGGFNGKDYE-ETIEKLSDSKDKFEVCGNM-VGRAGFGACVFRGRIYVAGGWN--TPCNTL 318
Cdd:PHA03098  376 LIFPRYNPCVVNVNNLIYVIGGISKNDELlKTVECFSLNTNKWSKGSPLpISHYGGCAIYHDGKIYVIGGISyiDNIKVY 455

                         170       180       190       200       210       220
                  ....*....|....*....|....*....|....*....|....*....|....*....|.
gi 1254049779 319 KTFQSYDPLTNTWKDEPSMNTGRKYFKLHATNEAIYAIRGCSHDWdLIKETERFDPQTLTW 379
Cdd:PHA03098  456 NIVESYNPVTNKWTELSSLNFPRINASLCIFNNKIYVVGGDKYEY-YINEIEVYDDKTNTW 515
PHA03098 PHA03098
kelch-like protein; Provisional
 152-282 3.82e-12

kelch-like protein; Provisional


Pssm-ID: 222983 [Multi-domain]  Cd Length: 534  Bit Score: 67.49  E-value: 3.82e-12
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1254049779 152 PKSHYAVVSSSTKVFIIGGMN-NGTYLNRVEMFDKEKGIRVECTRLMHGRTRTSACIHEDAIYAVGGYdaTYMSSVEIYD 230
Cdd:PHA03098  379 PRYNPCVVNVNNLIYVIGGISkNDELLKTVECFSLNTNKWSKGSPLPISHYGGCAIYHDGKIYVIGGI--SYIDNIKVYN 456

                          90       100       110       120       130
                  ....*....|....*....|....*....|....*....|....*....|....*..
gi 1254049779 231 IKTGGD-----WTTGPSLNNRRADASVVSFYGQLFVLGGFNGKDYEETIEKLSDSKD 282
Cdd:PHA03098  457 IVESYNpvtnkWTELSSLNFPRINASLCIFNNKIYVVGGDKYEYYINEIEVYDDKTN 513
Kelch smart00612
Kelch domain;
304-351 6.78e-12

Kelch domain;


Pssm-ID: 128874 [Multi-domain]  Cd Length: 47  Bit Score: 59.88  E-value: 6.78e-12
                           10        20        30        40
                   ....*....|....*....|....*....|....*....|....*...
gi 1254049779  304 RIYVAGGWNtPCNTLKTFQSYDPLTNTWKDEPSMNTGRKYFKLHATNE 351
Cdd:smart00612   1 KIYVVGGFD-GGQRLKSVEVYDPETNKWTPLPSMPTPRSGHGVAVING 47
PHA03098 PHA03098
kelch-like protein; Provisional
 187-381 1.78e-11

kelch-like protein; Provisional


Pssm-ID: 222983 [Multi-domain]  Cd Length: 534  Bit Score: 65.56  E-value: 1.78e-11
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1254049779 187 KGIRVECTRLMHGRTRTSAciHEDAIYAVGGYDATYMSSVEIYDIKTggDWTTGPSLNNRRADASVVsFYGQLFVLGGFN 266
Cdd:PHA03098  230 KIIYSKKYNLNKILPRSST--FGSIIYIHITMSIFTYNYITNYSPLS--EINTIIDIHYVYCFGSVV-LNNVIYFIGGMN 304

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1254049779 267 GKDY--EETIEKLSDSKDKFEVCGNMVGRAGFGACVFRGRIYVAGGWNTPCNtLKTFQSYDPLTNTWKDEPSMNTGRKYF 344
Cdd:PHA03098  305 KNNLsvNSVVSYDTKTKSWNKVPELIYPRKNPGVTVFNNRIYVIGGIYNSIS-LNTVESWKPGESKWREEPPLIFPRYNP 383

                         170       180       190
                  ....*....|....*....|....*....|....*..
gi 1254049779 345 KLHATNEAIYAIRGCSHDWDLIKETERFDPQTLTWAT 381
Cdd:PHA03098  384 CVVNVNNLIYVIGGISKNDELLKTVECFSLNTNKWSK 420
Kelch_1 pfam01344
Kelch motif; The kelch motif was initially discovered in Kelch. In this protein there are six ...
 293-338 6.10e-11

Kelch motif; The kelch motif was initially discovered in Kelch. In this protein there are six copies of the motif. It has been shown that Swiss:Q04652 is related to Galactose Oxidase for which a structure has been solved. The kelch motif forms a beta sheet. Several of these sheets associate to form a beta propeller structure as found in pfam00064, pfam00400 and pfam00415.


Pssm-ID: 396078 [Multi-domain]  Cd Length: 46  Bit Score: 56.85  E-value: 6.10e-11
                          10        20        30        40
                  ....*....|....*....|....*....|....*....|....*.
gi 1254049779 293 RAGFGACVFRGRIYVAGGWNtPCNTLKTFQSYDPLTNTWKDEPSMN 338
Cdd:pfam01344   2 RSGAGVVVVGGKIYVIGGFD-GNQSLNSVEVYDPETNTWSKLPSMP 46
Kelch smart00612
Kelch domain;
164-210 3.30e-10

Kelch domain;


Pssm-ID: 128874 [Multi-domain]  Cd Length: 47  Bit Score: 54.87  E-value: 3.30e-10
                           10        20        30        40
                   ....*....|....*....|....*....|....*....|....*..
gi 1254049779  164 KVFIIGGMNNGTYLNRVEMFDKEKGIRVECTRLMHGRTRTSACIHED 210
Cdd:smart00612   1 KIYVVGGFDGGQRLKSVEVYDPETNKWTPLPSMPTPRSGHGVAVING 47
Kelch smart00612
Kelch domain;
212-257 2.74e-09

Kelch domain;


Pssm-ID: 128874 [Multi-domain]  Cd Length: 47  Bit Score: 52.18  E-value: 2.74e-09
                           10        20        30        40
                   ....*....|....*....|....*....|....*....|....*..
gi 1254049779  212 IYAVGGYD-ATYMSSVEIYDIKTGgDWTTGPSLNNRRADASVVSFYG 257
Cdd:smart00612   2 IYVVGGFDgGQRLKSVEVYDPETN-KWTPLPSMPTPRSGHGVAVING 47
Kelch smart00612
Kelch domain;
258-303 3.78e-09

Kelch domain;


Pssm-ID: 128874 [Multi-domain]  Cd Length: 47  Bit Score: 51.79  E-value: 3.78e-09
                           10        20        30        40
                   ....*....|....*....|....*....|....*....|....*..
gi 1254049779  258 QLFVLGGFNGKDYEETIEKLSDSKDKFEVCGNM-VGRAGFGACVFRG 303
Cdd:smart00612   1 KIYVVGGFDGGQRLKSVEVYDPETNKWTPLPSMpTPRSGHGVAVING 47
PHA02713 PHA02713
hypothetical protein; Provisional
 66-340 4.21e-08

hypothetical protein; Provisional


Pssm-ID: 165086 [Multi-domain]  Cd Length: 557  Bit Score: 55.02  E-value: 4.21e-08
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1254049779  66 YEGKDNLKCITMIHDITSLMEVADTKL--KNYINTLNSKEQIFMVDDGVLNMDP----ILVADRKQNSREPLFIGYfKPD 139
Cdd:PHA02713  202 YITEEQLLCILSCIDIQNLDKKSRLLLysNKTINMYPSCIQFLLDNKQNRNIIPrqlcLVCHDTKYNVCNPCILVY-NIN 280

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1254049779 140 TMSFMPIGRLPNPKSHYAVVSSSTKVFIIGGMN-NGTYLNRVEMFDKEKGIRVECTRLMHGRTRTSACIHEDAIYAVGGY 218
Cdd:PHA02713  281 TMEYSVISTIPNHIINYASAIVDNEIIIAGGYNfNNPSLNKVYKINIENKIHVELPPMIKNRCRFSLAVIDDTIYAIGGQ 360

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1254049779 219 datymssveiydiktggdwttgpslnnrradasvvsfygqlfvlggfNGKDYEETIEKLSDSKDKFEVCGNM-VGRAGFG 297
Cdd:PHA02713  361 -----------------------------------------------NGTNVERTIECYTMGDDKWKMLPDMpIALSSYG 393

                         250       260       270       280       290       300
                  ....*....|....*....|....*....|....*....|....*....|....*....|
gi 1254049779 298 ACVFRGRIYVAGGWN-----TPCNTLKTFQ------------SYDPLTNTWKDEPSMNTG 340
Cdd:PHA02713  394 MCVLDQYIYIIGGRTehidyTSVHHMNSIDmeedthssnkviRYDTVNNIWETLPNFWTG 453
Kelch_1 pfam01344
Kelch motif; The kelch motif was initially discovered in Kelch. In this protein there are six ...
 200-244 1.30e-07

Kelch motif; The kelch motif was initially discovered in Kelch. In this protein there are six copies of the motif. It has been shown that Swiss:Q04652 is related to Galactose Oxidase for which a structure has been solved. The kelch motif forms a beta sheet. Several of these sheets associate to form a beta propeller structure as found in pfam00064, pfam00400 and pfam00415.


Pssm-ID: 396078 [Multi-domain]  Cd Length: 46  Bit Score: 47.61  E-value: 1.30e-07
                          10        20        30        40
                  ....*....|....*....|....*....|....*....|....*.
gi 1254049779 200 RTRTSACIHEDAIYAVGGYDA-TYMSSVEIYDIKTgGDWTTGPSLN 244
Cdd:pfam01344   2 RSGAGVVVVGGKIYVIGGFDGnQSLNSVEVYDPET-NTWSKLPSMP 46
Kelch_6 pfam13964
Kelch motif;
293-341 1.39e-07

Kelch motif;


Pssm-ID: 404790 [Multi-domain]  Cd Length: 50  Bit Score: 47.72  E-value: 1.39e-07
                          10        20        30        40
                  ....*....|....*....|....*....|....*....|....*....
gi 1254049779 293 RAGFGACVFRGRIYVAGGWNTPCNTLKTFQSYDPLTNTWKDEPSMNTGR 341
Cdd:pfam13964   2 RTFHSVVSVGGYIYVFGGYTNASPALNKLEVYNPLTKSWEELPPLPTPR 50
Kelch_1 pfam01344
Kelch motif; The kelch motif was initially discovered in Kelch. In this protein there are six ...
 246-290 5.44e-07

Kelch motif; The kelch motif was initially discovered in Kelch. In this protein there are six copies of the motif. It has been shown that Swiss:Q04652 is related to Galactose Oxidase for which a structure has been solved. The kelch motif forms a beta sheet. Several of these sheets associate to form a beta propeller structure as found in pfam00064, pfam00400 and pfam00415.


Pssm-ID: 396078 [Multi-domain]  Cd Length: 46  Bit Score: 45.68  E-value: 5.44e-07
                          10        20        30        40
                  ....*....|....*....|....*....|....*....|....*
gi 1254049779 246 RRADASVVSFYGQLFVLGGFNGKDYEETIEKLSDSKDKFEVCGNM 290
Cdd:pfam01344   1 RRSGAGVVVVGGKIYVIGGFDGNQSLNSVEVYDPETNTWSKLPSM 45
Kelch_1 pfam01344
Kelch motif; The kelch motif was initially discovered in Kelch. In this protein there are six ...
 152-197 1.99e-06

Kelch motif; The kelch motif was initially discovered in Kelch. In this protein there are six copies of the motif. It has been shown that Swiss:Q04652 is related to Galactose Oxidase for which a structure has been solved. The kelch motif forms a beta sheet. Several of these sheets associate to form a beta propeller structure as found in pfam00064, pfam00400 and pfam00415.


Pssm-ID: 396078 [Multi-domain]  Cd Length: 46  Bit Score: 44.14  E-value: 1.99e-06
                          10        20        30        40
                  ....*....|....*....|....*....|....*....|....*.
gi 1254049779 152 PKSHYAVVSSSTKVFIIGGMNNGTYLNRVEMFDKEKGIRVECTRLM 197
Cdd:pfam01344   1 RRSGAGVVVVGGKIYVIGGFDGNQSLNSVEVYDPETNTWSKLPSMP 46
Kelch_6 pfam13964
Kelch motif;
200-247 2.75e-05

Kelch motif;


Pssm-ID: 404790 [Multi-domain]  Cd Length: 50  Bit Score: 41.17  E-value: 2.75e-05
                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|
gi 1254049779 200 RTRTSACIHEDAIYAVGGYD--ATYMSSVEIYDIKTGGdWTTGPSLNNRR 247
Cdd:pfam13964   2 RTFHSVVSVGGYIYVFGGYTnaSPALNKLEVYNPLTKS-WEELPPLPTPR 50
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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