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Conserved domains on  [gi|281365345|ref|NP_523613|]
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no mechanoreceptor potential B, isoform C [Drosophila melanogaster]

Protein Classification

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
LapB COG2956
Lipopolysaccharide biosynthesis regulator YciM/LapB, contains six TPR domains and a C-terminal ...
 454-710 1.41e-16

Lipopolysaccharide biosynthesis regulator YciM/LapB, contains six TPR domains and a C-terminal metal-binding domain [Cell wall/membrane/envelope biogenesis];


:

Pssm-ID: 442196 [Multi-domain]  Cd Length: 275  Bit Score: 80.93  E-value: 1.41e-16
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 281365345 454 LNKALVYLRQNDVHQAIETL-QMYDRKSEgsmTASALTNLSFIYISLGNLEMASHCVNQLHEIGslKNNAPGLINAGIVE 532
Cdd:COG2956   12 YFKGLNYLLNGQPDKAIDLLeEALELDPE---TVEAHLALGNLYRRRGEYDRAIRIHQKLLERD--PDRAEALLELAQDY 86

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 281365345 533 LGSHNLILASERFEGALQLQPMNFEARYNLGLVALAQNDYELAEERFELLkeqlmLPSSVQHSHVFYQLAKLQERRLEsg 612
Cdd:COG2956   87 LKAGLLDRAEELLEKLLELDPDDAEALRLLAEIYEQEGDWEKAIEVLERL-----LKLGPENAHAYCELAELYLEQGD-- 159

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 281365345 613 lisnftPGAALQAYLQVVGISASDIDSRLFEkvGSLYEQIQDHQEANQYYNEAYRINMSDIGIASSIGSYYIKLQATERA 692
Cdd:COG2956  160 ------YDEAIEALEKALKLDPDCARALLLL--AELYLEQGDYEEAIAALERALEQDPDYLPALPRLAELYEKLGDPEEA 231

                        250
                 ....*....|....*...
gi 281365345 693 LFYYERAVLADPNDPNLM 710
Cdd:COG2956  232 LELLRKALELDPSDDLLL 249
TPR super family cl33886
Tetratricopeptide (TPR) repeat [General function prediction only];
183-316 2.91e-04

Tetratricopeptide (TPR) repeat [General function prediction only];


The actual alignment was detected with superfamily member COG0457:

Pssm-ID: 440225 [Multi-domain]  Cd Length: 245  Bit Score: 43.46  E-value: 2.91e-04
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 281365345 183 YAVFFNLAEQYERSEMHIEALNTY--SImaknKMFPHVNQLKLNMGNIYYSMGIYQKAVKMYRMALDSVPKSlsqlrLKI 260
Cdd:COG0457    8 AEAYNNLGLAYRRLGRYEEAIEDYekAL----ELDPDDAEALYNLGLAYLRLGRYEEALADYEQALELDPDD-----AEA 78

                         90       100       110       120       130
                 ....*....|....*....|....*....|....*....|....*....|....*..
gi 281365345 261 RENIGILFIRMGSYSDAASSFE-FIMTERANIRSSIHLLLCYFALGDVEKVKLAFRR 316
Cdd:COG0457   79 LNNLGLALQALGRYEEALEDYDkALELDPDDAEALYNLGLALLELGRYDEAIEAYER 135
 
Name Accession Description Interval E-value
LapB COG2956
Lipopolysaccharide biosynthesis regulator YciM/LapB, contains six TPR domains and a C-terminal ...
 454-710 1.41e-16

Lipopolysaccharide biosynthesis regulator YciM/LapB, contains six TPR domains and a C-terminal metal-binding domain [Cell wall/membrane/envelope biogenesis];


Pssm-ID: 442196 [Multi-domain]  Cd Length: 275  Bit Score: 80.93  E-value: 1.41e-16
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 281365345 454 LNKALVYLRQNDVHQAIETL-QMYDRKSEgsmTASALTNLSFIYISLGNLEMASHCVNQLHEIGslKNNAPGLINAGIVE 532
Cdd:COG2956   12 YFKGLNYLLNGQPDKAIDLLeEALELDPE---TVEAHLALGNLYRRRGEYDRAIRIHQKLLERD--PDRAEALLELAQDY 86

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 281365345 533 LGSHNLILASERFEGALQLQPMNFEARYNLGLVALAQNDYELAEERFELLkeqlmLPSSVQHSHVFYQLAKLQERRLEsg 612
Cdd:COG2956   87 LKAGLLDRAEELLEKLLELDPDDAEALRLLAEIYEQEGDWEKAIEVLERL-----LKLGPENAHAYCELAELYLEQGD-- 159

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 281365345 613 lisnftPGAALQAYLQVVGISASDIDSRLFEkvGSLYEQIQDHQEANQYYNEAYRINMSDIGIASSIGSYYIKLQATERA 692
Cdd:COG2956  160 ------YDEAIEALEKALKLDPDCARALLLL--AELYLEQGDYEEAIAALERALEQDPDYLPALPRLAELYEKLGDPEEA 231

                        250
                 ....*....|....*...
gi 281365345 693 LFYYERAVLADPNDPNLM 710
Cdd:COG2956  232 LELLRKALELDPSDDLLL 249
PEP_TPR_lipo TIGR02917
putative PEP-CTERM system TPR-repeat lipoprotein; This protein family occurs in strictly ...
 456-750 1.47e-07

putative PEP-CTERM system TPR-repeat lipoprotein; This protein family occurs in strictly within a subset of Gram-negative bacterial species with the proposed PEP-CTERM/exosortase system, analogous to the LPXTG/sortase system common in Gram-positive bacteria. This protein occurs in a species if and only if a transmembrane histidine kinase (TIGR02916) and a DNA-binding response regulator (TIGR02915) also occur. The present of tetratricopeptide repeats (TPR) suggests protein-protein interaction, possibly for the regulation of PEP-CTERM protein expression, since many PEP-CTERM proteins in these genomes are preceded by a proposed DNA binding site for the response regulator.


Pssm-ID: 274350 [Multi-domain]  Cd Length: 899  Bit Score: 55.47  E-value: 1.47e-07
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 281365345  456 KALVYLRQNDVHQAIETLQMYDRKSEGSMTASALtnLSFIYISLGNLEMASHCVNQ-------------------LHE-- 514
Cdd:TIGR02917 267 KALVDFQKKNYEDARETLQDALKSAPEYLPALLL--AGASEYQLGNLEQAYQYLNQilkyapnshqarrllasiqLRLgr 344

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 281365345  515 -----------IGSLKNNAPGLINAGIVELGSHNLILASERFEGALQLQPMNFEARYNLGLVALAQNDYELAEERFEllk 583
Cdd:TIGR02917 345 vdeaiatlspaLGLDPDDPAALSLLGEAYLALGDFEKAAEYLAKATELDPENAAARTQLGISKLSQGDPSEAIADLE--- 421

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 281365345  584 EQLMLPSSVQHSHVFYQLAKLQERRLESGLisnftpgAALQAYLQVVGISASdidsrLFEKVGSLYEQIQDHQEANQYYN 663
Cdd:TIGR02917 422 TAAQLDPELGRADLLLILSYLRSGQFDKAL-------AAAKKLEKKQPDNAS-----LHNLLGAIYLGKGDLAKAREAFE 489

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 281365345  664 EAYRINMSDIGIASSIGSYYIKLQATERALFYYERAVLADPNDPNLMLRIAScFRNSYLPTKQYLGLFQKIHARFPDNLT 743
Cdd:TIGR02917 490 KALSIEPDFFPAAANLARIDIQEGNPDDAIQRFEKVLTIDPKNLRAILALAG-LYLRTGNEEEAVAWLEKAAELNPQEIE 568


                  ....*..
gi 281365345  744 CIRALMQ 750
Cdd:TIGR02917 569 PALALAQ 575
TPR COG0457
Tetratricopeptide (TPR) repeat [General function prediction only];
183-316 2.91e-04

Tetratricopeptide (TPR) repeat [General function prediction only];


Pssm-ID: 440225 [Multi-domain]  Cd Length: 245  Bit Score: 43.46  E-value: 2.91e-04
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 281365345 183 YAVFFNLAEQYERSEMHIEALNTY--SImaknKMFPHVNQLKLNMGNIYYSMGIYQKAVKMYRMALDSVPKSlsqlrLKI 260
Cdd:COG0457    8 AEAYNNLGLAYRRLGRYEEAIEDYekAL----ELDPDDAEALYNLGLAYLRLGRYEEALADYEQALELDPDD-----AEA 78

                         90       100       110       120       130
                 ....*....|....*....|....*....|....*....|....*....|....*..
gi 281365345 261 RENIGILFIRMGSYSDAASSFE-FIMTERANIRSSIHLLLCYFALGDVEKVKLAFRR 316
Cdd:COG0457   79 LNNLGLALQALGRYEEALEDYDkALELDPDDAEALYNLGLALLELGRYDEAIEAYER 135
TPR smart00028
Tetratricopeptide repeats; Repeats present in 4 or more copies in proteins. Contain a minimum ...
 223-251 5.44e-03

Tetratricopeptide repeats; Repeats present in 4 or more copies in proteins. Contain a minimum of 34 amino acids each and self-associate via a "knobs and holes" mechanism.


Pssm-ID: 197478 [Multi-domain]  Cd Length: 34  Bit Score: 35.11  E-value: 5.44e-03
                           10        20
                   ....*....|....*....|....*....
gi 281365345   223 LNMGNIYYSMGIYQKAVKMYRMALDSVPK 251
Cdd:smart00028   5 YNLGNAYLKLGDYDEALEYYEKALELDPN 33
TPR_1 pfam00515
Tetratricopeptide repeat;
224-247 7.74e-03

Tetratricopeptide repeat;


Pssm-ID: 459840 [Multi-domain]  Cd Length: 34  Bit Score: 34.70  E-value: 7.74e-03
                          10        20
                  ....*....|....*....|....
gi 281365345  224 NMGNIYYSMGIYQKAVKMYRMALD 247
Cdd:pfam00515   6 NLGNAYFKLGKYDEALEYYEKALE 29
 
Name Accession Description Interval E-value
LapB COG2956
Lipopolysaccharide biosynthesis regulator YciM/LapB, contains six TPR domains and a C-terminal ...
 454-710 1.41e-16

Lipopolysaccharide biosynthesis regulator YciM/LapB, contains six TPR domains and a C-terminal metal-binding domain [Cell wall/membrane/envelope biogenesis];


Pssm-ID: 442196 [Multi-domain]  Cd Length: 275  Bit Score: 80.93  E-value: 1.41e-16
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 281365345 454 LNKALVYLRQNDVHQAIETL-QMYDRKSEgsmTASALTNLSFIYISLGNLEMASHCVNQLHEIGslKNNAPGLINAGIVE 532
Cdd:COG2956   12 YFKGLNYLLNGQPDKAIDLLeEALELDPE---TVEAHLALGNLYRRRGEYDRAIRIHQKLLERD--PDRAEALLELAQDY 86

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 281365345 533 LGSHNLILASERFEGALQLQPMNFEARYNLGLVALAQNDYELAEERFELLkeqlmLPSSVQHSHVFYQLAKLQERRLEsg 612
Cdd:COG2956   87 LKAGLLDRAEELLEKLLELDPDDAEALRLLAEIYEQEGDWEKAIEVLERL-----LKLGPENAHAYCELAELYLEQGD-- 159

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 281365345 613 lisnftPGAALQAYLQVVGISASDIDSRLFEkvGSLYEQIQDHQEANQYYNEAYRINMSDIGIASSIGSYYIKLQATERA 692
Cdd:COG2956  160 ------YDEAIEALEKALKLDPDCARALLLL--AELYLEQGDYEEAIAALERALEQDPDYLPALPRLAELYEKLGDPEEA 231

                        250
                 ....*....|....*...
gi 281365345 693 LFYYERAVLADPNDPNLM 710
Cdd:COG2956  232 LELLRKALELDPSDDLLL 249
LapB COG2956
Lipopolysaccharide biosynthesis regulator YciM/LapB, contains six TPR domains and a C-terminal ...
 524-799 2.80e-13

Lipopolysaccharide biosynthesis regulator YciM/LapB, contains six TPR domains and a C-terminal metal-binding domain [Cell wall/membrane/envelope biogenesis];


Pssm-ID: 442196 [Multi-domain]  Cd Length: 275  Bit Score: 70.91  E-value: 2.80e-13
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 281365345 524 GLINAGIVELGSHNLILASERFEGALQLQPMNFEARYNLGLVALAQNDYELAEERFELLKEQlmlpsSVQHSHVFYQLAK 603
Cdd:COG2956   10 GWYFKGLNYLLNGQPDKAIDLLEEALELDPETVEAHLALGNLYRRRGEYDRAIRIHQKLLER-----DPDRAEALLELAQ 84

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 281365345 604 LQerrLESGLISNftpgaALQAYLQVVGISASDIDSRlfEKVGSLYEQIQDHQEANQYYNEAYRINMSDIGIASSIGSYY 683
Cdd:COG2956   85 DY---LKAGLLDR-----AEELLEKLLELDPDDAEAL--RLLAEIYEQEGDWEKAIEVLERLLKLGPENAHAYCELAELY 154

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 281365345 684 IKLQATERALFYYERAVLADPNDPNLMLRIAscfrNSYLPTKQY---LGLFQKIHARFPDNLTCIRALMQVTKSLELGDL 760
Cdd:COG2956  155 LEQGDYDEAIEALEKALKLDPDCARALLLLA----ELYLEQGDYeeaIAALERALEQDPDYLPALPRLAELYEKLGDPEE 230

                        250       260       270       280
                 ....*....|....*....|....*....|....*....|.
gi 281365345 761 YERYASEYTRLQSQQQERQSEQRY--QQQRFPSAAKFSNRL 799
Cdd:COG2956  231 ALELLRKALELDPSDDLLLALADLleRKEGLEAALALLERQ 271
LapB COG2956
Lipopolysaccharide biosynthesis regulator YciM/LapB, contains six TPR domains and a C-terminal ...
 457-669 2.48e-12

Lipopolysaccharide biosynthesis regulator YciM/LapB, contains six TPR domains and a C-terminal metal-binding domain [Cell wall/membrane/envelope biogenesis];


Pssm-ID: 442196 [Multi-domain]  Cd Length: 275  Bit Score: 68.22  E-value: 2.48e-12
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 281365345 457 ALVYLRQNDVHQAIETLQMYDRKSEGSmtASALTNLSFIYISLGNLEMASHCVNQLHEIGSlkNNAPGLINAGIVELGSH 536
Cdd:COG2956   83 AQDYLKAGLLDRAEELLEKLLELDPDD--AEALRLLAEIYEQEGDWEKAIEVLERLLKLGP--ENAHAYCELAELYLEQG 158

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 281365345 537 NLILASERFEGALQLQPMNFEARYNLGLVALAQNDYELAEERFELLKEQlmlpsSVQHSHVFYQLAKLQERRLEsglisn 616
Cdd:COG2956  159 DYDEAIEALEKALKLDPDCARALLLLAELYLEQGDYEEAIAALERALEQ-----DPDYLPALPRLAELYEKLGD------ 227

                        170       180       190       200       210
                 ....*....|....*....|....*....|....*....|....*....|...
gi 281365345 617 ftPGAALQAYLQVVgisASDIDSRLFEKVGSLYEQIQDHQEANQYYNEAYRIN 669
Cdd:COG2956  228 --PEEALELLRKAL---ELDPSDDLLLALADLLERKEGLEAALALLERQLRRH 275
TPR COG0457
Tetratricopeptide (TPR) repeat [General function prediction only];
549-803 3.95e-11

Tetratricopeptide (TPR) repeat [General function prediction only];


Pssm-ID: 440225 [Multi-domain]  Cd Length: 245  Bit Score: 64.26  E-value: 3.95e-11
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 281365345 549 LQLQPMNFEARYNLGLVALAQNDYELAEERFELLKEQlmlpsSVQHSHVFYQLAKLQERRLEsglisnftPGAALQAYLQ 628
Cdd:COG0457    1 LELDPDDAEAYNNLGLAYRRLGRYEEAIEDYEKALEL-----DPDDAEALYNLGLAYLRLGR--------YEEALADYEQ 67

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 281365345 629 VVGISASDIDSRLfeKVGSLYEQIQDHQEANQYYNEAYRINMSDIGIASSIGSYYIKLQATERALFYYERAVLADPNDPN 708
Cdd:COG0457   68 ALELDPDDAEALN--NLGLALQALGRYEEALEDYDKALELDPDDAEALYNLGLALLELGRYDEAIEAYERALELDPDDAD 145

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 281365345 709 LMLRIASCFRNSYlPTKQYLGLFQKIHARFPDNLTCIRALMQVTKSLELGDLYERYASEYTRLQSQQQERQSEQRYQQQR 788
Cdd:COG0457  146 ALYNLGIALEKLG-RYEEALELLEKLEAAALAALLAAALGEAALALAAAEVLLALLLALEQALRKKLAILTLAALAELLL 224

                        250
                 ....*....|....*
gi 281365345 789 FPSAAKFSNRLRFLQ 803
Cdd:COG0457  225 LALALLLALRLAALA 239
TPR COG0457
Tetratricopeptide (TPR) repeat [General function prediction only];
486-714 7.15e-09

Tetratricopeptide (TPR) repeat [General function prediction only];


Pssm-ID: 440225 [Multi-domain]  Cd Length: 245  Bit Score: 57.32  E-value: 7.15e-09
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 281365345 486 ASALTNLSFIYISLGNLEMASHCVNQLHEIGSlkNNAPGLINAGIVELGSHNLILASERFEGALQLQPMNFEARYNLGLV 565
Cdd:COG0457    8 AEAYNNLGLAYRRLGRYEEAIEDYEKALELDP--DDAEALYNLGLAYLRLGRYEEALADYEQALELDPDDAEALNNLGLA 85

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 281365345 566 ALAQNDYElaeerfellkeqlmlpssvqhshvfyqlaklqerrlesglisnftpgAALQAYLQVVGISASDIDSrlFEKV 645
Cdd:COG0457   86 LQALGRYE-----------------------------------------------EALEDYDKALELDPDDAEA--LYNL 116

                        170       180       190       200       210       220
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 281365345 646 GSLYEQIQDHQEANQYYNEAYRINMSDIGIASSIGSYYIKLQATERALFYYERAVLADPNDPNLMLRIA 714
Cdd:COG0457  117 GLALLELGRYDEAIEAYERALELDPDDADALYNLGIALEKLGRYEEALELLEKLEAAALAALLAAALGE 185
NrfG COG4235
Cytochrome c-type biogenesis protein CcmH/NrfG [Energy production and conversion, ...
 486-586 7.48e-09

Cytochrome c-type biogenesis protein CcmH/NrfG [Energy production and conversion, Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 443378 [Multi-domain]  Cd Length: 131  Bit Score: 54.63  E-value: 7.48e-09
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 281365345 486 ASALTNLSFIYISLGNLEMASHCVNQLHEIgsLKNNAPGLINAGIVELGSHNLILASERFEGALQLQPMNFEARYNLGLV 565
Cdd:COG4235   17 AEGWLLLGRAYLRLGRYDEALAAYEKALRL--DPDNADALLDLAEALLAAGDTEEAEELLERALALDPDNPEALYLLGLA 94

                         90       100
                 ....*....|....*....|.
gi 281365345 566 ALAQNDYELAEERFELLKEQL 586
Cdd:COG4235   95 AFQQGDYAEAIAAWQKLLALL 115
BepA COG4783
Outer membrane protein chaperone/metalloprotease BepA/YfgC, contains M48 and TPR domains [Cell ...
 621-741 1.17e-08

Outer membrane protein chaperone/metalloprotease BepA/YfgC, contains M48 and TPR domains [Cell wall/membrane/envelope biogenesis, Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 443813 [Multi-domain]  Cd Length: 139  Bit Score: 54.43  E-value: 1.17e-08
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 281365345 621 AALQAYLQVvgISASDIDSRLFEKVGSLYEQIQDHQEANQYYNEAYRINMSDIGIASSIGSYYIKLQATERALFYYERAV 700
Cdd:COG4783   22 EAEALLEKA--LELDPDNPEAFALLGEILLQLGDLDEAIVLLHEALELDPDEPEARLNLGLALLKAGDYDEALALLEKAL 99

                         90       100       110       120
                 ....*....|....*....|....*....|....*....|.
gi 281365345 701 LADPNDPNLMLRIASCFRNSYLPtKQYLGLFQKIHARFPDN 741
Cdd:COG4783  100 KLDPEHPEAYLRLARAYRALGRP-DEAIAALEKALELDPDD 139
TPR COG0457
Tetratricopeptide (TPR) repeat [General function prediction only];
455-580 2.49e-08

Tetratricopeptide (TPR) repeat [General function prediction only];


Pssm-ID: 440225 [Multi-domain]  Cd Length: 245  Bit Score: 55.78  E-value: 2.49e-08
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 281365345 455 NKALVYLRQNDVHQAIETLQMYDRKSEGSmtASALTNLSFIYISLGNLEMASHCVNQLHEIGSlkNNAPGLINAGIVELG 534
Cdd:COG0457   13 NLGLAYRRLGRYEEAIEDYEKALELDPDD--AEALYNLGLAYLRLGRYEEALADYEQALELDP--DDAEALNNLGLALQA 88

                         90       100       110       120
                 ....*....|....*....|....*....|....*....|....*.
gi 281365345 535 SHNLILASERFEGALQLQPMNFEARYNLGLVALAQNDYELAEERFE 580
Cdd:COG0457   89 LGRYEEALEDYDKALELDPDDAEALYNLGLALLELGRYDEAIEAYE 134
PEP_TPR_lipo TIGR02917
putative PEP-CTERM system TPR-repeat lipoprotein; This protein family occurs in strictly ...
 456-750 1.47e-07

putative PEP-CTERM system TPR-repeat lipoprotein; This protein family occurs in strictly within a subset of Gram-negative bacterial species with the proposed PEP-CTERM/exosortase system, analogous to the LPXTG/sortase system common in Gram-positive bacteria. This protein occurs in a species if and only if a transmembrane histidine kinase (TIGR02916) and a DNA-binding response regulator (TIGR02915) also occur. The present of tetratricopeptide repeats (TPR) suggests protein-protein interaction, possibly for the regulation of PEP-CTERM protein expression, since many PEP-CTERM proteins in these genomes are preceded by a proposed DNA binding site for the response regulator.


Pssm-ID: 274350 [Multi-domain]  Cd Length: 899  Bit Score: 55.47  E-value: 1.47e-07
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 281365345  456 KALVYLRQNDVHQAIETLQMYDRKSEGSMTASALtnLSFIYISLGNLEMASHCVNQ-------------------LHE-- 514
Cdd:TIGR02917 267 KALVDFQKKNYEDARETLQDALKSAPEYLPALLL--AGASEYQLGNLEQAYQYLNQilkyapnshqarrllasiqLRLgr 344

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 281365345  515 -----------IGSLKNNAPGLINAGIVELGSHNLILASERFEGALQLQPMNFEARYNLGLVALAQNDYELAEERFEllk 583
Cdd:TIGR02917 345 vdeaiatlspaLGLDPDDPAALSLLGEAYLALGDFEKAAEYLAKATELDPENAAARTQLGISKLSQGDPSEAIADLE--- 421

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 281365345  584 EQLMLPSSVQHSHVFYQLAKLQERRLESGLisnftpgAALQAYLQVVGISASdidsrLFEKVGSLYEQIQDHQEANQYYN 663
Cdd:TIGR02917 422 TAAQLDPELGRADLLLILSYLRSGQFDKAL-------AAAKKLEKKQPDNAS-----LHNLLGAIYLGKGDLAKAREAFE 489

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 281365345  664 EAYRINMSDIGIASSIGSYYIKLQATERALFYYERAVLADPNDPNLMLRIAScFRNSYLPTKQYLGLFQKIHARFPDNLT 743
Cdd:TIGR02917 490 KALSIEPDFFPAAANLARIDIQEGNPDDAIQRFEKVLTIDPKNLRAILALAG-LYLRTGNEEEAVAWLEKAAELNPQEIE 568


                  ....*..
gi 281365345  744 CIRALMQ 750
Cdd:TIGR02917 569 PALALAQ 575
TPR COG0457
Tetratricopeptide (TPR) repeat [General function prediction only];
455-586 1.81e-07

Tetratricopeptide (TPR) repeat [General function prediction only];


Pssm-ID: 440225 [Multi-domain]  Cd Length: 245  Bit Score: 53.09  E-value: 1.81e-07
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 281365345 455 NKALVYLRQNDVHQAIETLQMYDRKSEGSmtASALTNLSFIYISLGNLEMASHCVNQLHEIGSlkNNAPGLINAGIVELG 534
Cdd:COG0457   47 NLGLAYLRLGRYEEALADYEQALELDPDD--AEALNNLGLALQALGRYEEALEDYDKALELDP--DDAEALYNLGLALLE 122

                         90       100       110       120       130
                 ....*....|....*....|....*....|....*....|....*....|..
gi 281365345 535 SHNLILASERFEGALQLQPMNFEARYNLGLVALAQNDYELAEERFELLKEQL 586
Cdd:COG0457  123 LGRYDEAIEAYERALELDPDDADALYNLGIALEKLGRYEEALELLEKLEAAA 174
Spy COG3914
Predicted O-linked N-acetylglucosamine transferase, SPINDLY family [Posttranslational ...
 443-719 1.96e-07

Predicted O-linked N-acetylglucosamine transferase, SPINDLY family [Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 443119 [Multi-domain]  Cd Length: 658  Bit Score: 54.61  E-value: 1.96e-07
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 281365345 443 SNLAWLANELELNKALVYLRQNDVHQAIETLQMYDrksegsmtASALTNLSFIYISLGNLEMASHCVNQLHEIGSlkNNA 522
Cdd:COG3914   43 LALLLLAALAEAAAAALLALAAGEAAAAAAALLLL--------AALLELAALLLQALGRYEEALALYRRALALNP--DNA 112

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 281365345 523 PGLINAGIVELGSHNLILASERFEGALQLQPMNFEARYNLGLVALAQNDYELAEERFELLKEQlmLPssvQHSHVFYQLA 602
Cdd:COG3914  113 EALFNLGNLLLALGRLEEALAALRRALALNPDFAEAYLNLGEALRRLGRLEEAIAALRRALEL--DP---DNAEALNNLG 187

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 281365345 603 KLQER--RLEsglisnftpgAALQAYLQVVGISASDID---SRLFekvgsLYEQIQDHQEANQYYNEAYRINMSDIGIAS 677
Cdd:COG3914  188 NALQDlgRLE----------EAIAAYRRALELDPDNADahsNLLF-----ALRQACDWEVYDRFEELLAALARGPSELSP 252

                        250       260       270       280       290       300
                 ....*....|....*....|....*....|....*....|....*....|....*....|
gi 281365345 678 SIGSY---------------YIKLQATERALFYYERAVLADPNDPnlmLRIA---SCFRN 719
Cdd:COG3914  253 FALLYlpdddpaellalaraWAQLVAAAAAPELPPPPNPRDPDRK---LRIGyvsADFRR 309
BepA COG4783
Outer membrane protein chaperone/metalloprotease BepA/YfgC, contains M48 and TPR domains [Cell ...
 449-585 7.78e-07

Outer membrane protein chaperone/metalloprotease BepA/YfgC, contains M48 and TPR domains [Cell wall/membrane/envelope biogenesis, Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 443813 [Multi-domain]  Cd Length: 139  Bit Score: 49.03  E-value: 7.78e-07
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 281365345 449 ANELELNKALVYLRQNDVHQAIETLQMYDRKSEGSmtASALTNLSFIYISLGNLEMAshcVNQLHEIGSL-KNNAPGLIN 527
Cdd:COG4783    3 CAEALYALAQALLLAGDYDEAEALLEKALELDPDN--PEAFALLGEILLQLGDLDEA---IVLLHEALELdPDEPEARLN 77

                         90       100       110       120       130
                 ....*....|....*....|....*....|....*....|....*....|....*...
gi 281365345 528 AGIVELGSHNLILASERFEGALQLQPMNFEARYNLGLVALAQNDYELAEERFELLKEQ 585
Cdd:COG4783   78 LGLALLKAGDYDEALALLEKALKLDPEHPEAYLRLARAYRALGRPDEAIAALEKALEL 135
PEP_TPR_lipo TIGR02917
putative PEP-CTERM system TPR-repeat lipoprotein; This protein family occurs in strictly ...
 456-715 1.92e-06

putative PEP-CTERM system TPR-repeat lipoprotein; This protein family occurs in strictly within a subset of Gram-negative bacterial species with the proposed PEP-CTERM/exosortase system, analogous to the LPXTG/sortase system common in Gram-positive bacteria. This protein occurs in a species if and only if a transmembrane histidine kinase (TIGR02916) and a DNA-binding response regulator (TIGR02915) also occur. The present of tetratricopeptide repeats (TPR) suggests protein-protein interaction, possibly for the regulation of PEP-CTERM protein expression, since many PEP-CTERM proteins in these genomes are preceded by a proposed DNA binding site for the response regulator.


Pssm-ID: 274350 [Multi-domain]  Cd Length: 899  Bit Score: 51.62  E-value: 1.92e-06
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 281365345  456 KALVYLRQNDVHQAIETLQmydrksEGSMTASALTN----LSFIYISLGNLEMASHCVNQLHEigSLKNNAPGLINAGIV 531
Cdd:TIGR02917 403 LGISKLSQGDPSEAIADLE------TAAQLDPELGRadllLILSYLRSGQFDKALAAAKKLEK--KQPDNASLHNLLGAI 474

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 281365345  532 ELGSHNLILASERFEGALQLQPMNFEARYNLGLVALAQNDYELAEERFEllkeqLMLPSSVQHSHVFYQLAKLQERRLES 611
Cdd:TIGR02917 475 YLGKGDLAKAREAFEKALSIEPDFFPAAANLARIDIQEGNPDDAIQRFE-----KVLTIDPKNLRAILALAGLYLRTGNE 549

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 281365345  612 ----GLIS--------NFTPGAALQAYLQVVG---------ISASDI---DSRLFEKVGSLYEQIQDHQEANQYYNEAYR 667
Cdd:TIGR02917 550 eeavAWLEkaaelnpqEIEPALALAQYYLGKGqlkkalailNEAADAapdSPEAWLMLGRAQLAAGDLNKAVSSFKKLLA 629

                         250       260       270       280
                  ....*....|....*....|....*....|....*....|....*...
gi 281365345  668 INMSDIGIASSIGSYYIKLQATERALFYYERAVLADPNDPNLMLRIAS 715
Cdd:TIGR02917 630 LQPDSALALLLLADAYAVMKNYAKAITSLKRALELKPDNTEAQIGLAQ 677
PEP_TPR_lipo TIGR02917
putative PEP-CTERM system TPR-repeat lipoprotein; This protein family occurs in strictly ...
 448-714 4.87e-06

putative PEP-CTERM system TPR-repeat lipoprotein; This protein family occurs in strictly within a subset of Gram-negative bacterial species with the proposed PEP-CTERM/exosortase system, analogous to the LPXTG/sortase system common in Gram-positive bacteria. This protein occurs in a species if and only if a transmembrane histidine kinase (TIGR02916) and a DNA-binding response regulator (TIGR02915) also occur. The present of tetratricopeptide repeats (TPR) suggests protein-protein interaction, possibly for the regulation of PEP-CTERM protein expression, since many PEP-CTERM proteins in these genomes are preceded by a proposed DNA binding site for the response regulator.


Pssm-ID: 274350 [Multi-domain]  Cd Length: 899  Bit Score: 50.47  E-value: 4.87e-06
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 281365345  448 LANELELNKAL---------------VYLRQNDVHQAIETLQMYDRKSEGSMtASALTNLSFIYISLGNLEMA------- 505
Cdd:TIGR02917  73 AAAEKELRKALslgypknqvlpllarAYLLQGKFQQVLDELPGKTLLDDEGA-AELLALRGLAYLGLGQLELAqksyeqa 151

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 281365345  506 -----------------SHCVNQLHEIGSLKNNA----PGLINA----GIVELGSHNLILASERFEGALQLQPMNFEARY 560
Cdd:TIGR02917 152 laidprslyaklglaqlALAENRFDEARALIDEVltadPGNVDAlllkGDLLLSLGNIELALAAYRKAIALRPNNIAVLL 231

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 281365345  561 NLGLVALAQNDYELAEERFELLKEQlmLPSSVQhSHVFYQLAKLQERRLESglisnftpgaALQAYLQVVGISASDIDSR 640
Cdd:TIGR02917 232 ALATILIEAGEFEEAEKHADALLKK--APNSPL-AHYLKALVDFQKKNYED----------ARETLQDALKSAPEYLPAL 298

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 281365345  641 LFekVGSLYEQIQDHQEANQYYNE----------AYRI------------------------NMSDIGIASSIGSYYIKL 686
Cdd:TIGR02917 299 LL--AGASEYQLGNLEQAYQYLNQilkyapnshqARRLlasiqlrlgrvdeaiatlspalglDPDDPAALSLLGEAYLAL 376

                         330       340
                  ....*....|....*....|....*...
gi 281365345  687 QATERALFYYERAVLADPNDPNLMLRIA 714
Cdd:TIGR02917 377 GDFEKAAEYLAKATELDPENAAARTQLG 404
BepA COG4783
Outer membrane protein chaperone/metalloprotease BepA/YfgC, contains M48 and TPR domains [Cell ...
 646-771 1.03e-05

Outer membrane protein chaperone/metalloprotease BepA/YfgC, contains M48 and TPR domains [Cell wall/membrane/envelope biogenesis, Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 443813 [Multi-domain]  Cd Length: 139  Bit Score: 45.95  E-value: 1.03e-05
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 281365345 646 GSLYEQIQDHQEANQYYNEAYRINMSDIGIASSIGSYYIKLQATERALFYYERAVLADPNDPNLMLRIASCfrnsYLPTK 725
Cdd:COG4783   11 AQALLLAGDYDEAEALLEKALELDPDNPEAFALLGEILLQLGDLDEAIVLLHEALELDPDEPEARLNLGLA----LLKAG 86

                         90       100       110       120
                 ....*....|....*....|....*....|....*....|....*....
gi 281365345 726 QY---LGLFQKIHARFPDNLTCIRALMQVTKSLELGDLYERYASEYTRL 771
Cdd:COG4783   87 DYdeaLALLEKALKLDPEHPEAYLRLARAYRALGRPDEAIAALEKALEL 135
TadD COG5010
Flp pilus assembly protein TadD, contains TPR repeats [Intracellular trafficking, secretion, ...
 495-580 1.75e-05

Flp pilus assembly protein TadD, contains TPR repeats [Intracellular trafficking, secretion, and vesicular transport, Extracellular structures];


Pssm-ID: 444034 [Multi-domain]  Cd Length: 155  Bit Score: 45.72  E-value: 1.75e-05
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 281365345 495 IYISLGNLEMASHCVNQLHEIGslKNNAPGLINAGIVELGSHNLILASERFEGALQLQPMNFEARYNLGLVALAQNDYEL 574
Cdd:COG5010   63 LYNKLGDFEESLALLEQALQLD--PNNPELYYNLALLYSRSGDKDEAKEYYEKALALSPDNPNAYSNLAALLLSLGQDDE 140


                 ....*.
gi 281365345 575 AEERFE 580
Cdd:COG5010  141 AKAALQ 146
BepA COG4783
Outer membrane protein chaperone/metalloprotease BepA/YfgC, contains M48 and TPR domains [Cell ...
 486-607 2.85e-05

Outer membrane protein chaperone/metalloprotease BepA/YfgC, contains M48 and TPR domains [Cell wall/membrane/envelope biogenesis, Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 443813 [Multi-domain]  Cd Length: 139  Bit Score: 44.80  E-value: 2.85e-05
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 281365345 486 ASALTNLSFIYISLGNLEMASHCVNQLHEIgsLKNNAPGLINAGIVELGSHNLILASERFEGALQLQPMNFEARYNLGLV 565
Cdd:COG4783    4 AEALYALAQALLLAGDYDEAEALLEKALEL--DPDNPEAFALLGEILLQLGDLDEAIVLLHEALELDPDEPEARLNLGLA 81

                         90       100       110       120
                 ....*....|....*....|....*....|....*....|..
gi 281365345 566 ALAQNDYELAEERFELLkeqlmLPSSVQHSHVFYQLAKLQER 607
Cdd:COG4783   82 LLKAGDYDEALALLEKA-----LKLDPEHPEAYLRLARAYRA 118
PilF COG3063
Type IV pilus assembly protein PilF/PilW [Cell motility, Extracellular structures];
495-580 4.85e-05

Type IV pilus assembly protein PilF/PilW [Cell motility, Extracellular structures];


Pssm-ID: 442297 [Multi-domain]  Cd Length: 94  Bit Score: 42.85  E-value: 4.85e-05
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 281365345 495 IYISLGNLEMASHCVNQLHEIGSlkNNAPGLINAGIVELGSHNLILAsERFEGALQLQPMNFEARYNLGLVALAQNDYEL 574
Cdd:COG3063    1 LYLKLGDLEEAEEYYEKALELDP--DNADALNNLGLLLLEQGRYDEA-IALEKALKLDPNNAEALLNLAELLLELGDYDE 77


                 ....*.
gi 281365345 575 AEERFE 580
Cdd:COG3063   78 ALAYLE 83
TadD COG5010
Flp pilus assembly protein TadD, contains TPR repeats [Intracellular trafficking, secretion, ...
 621-714 1.05e-04

Flp pilus assembly protein TadD, contains TPR repeats [Intracellular trafficking, secretion, and vesicular transport, Extracellular structures];


Pssm-ID: 444034 [Multi-domain]  Cd Length: 155  Bit Score: 43.41  E-value: 1.05e-04
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 281365345 621 AALQAYLQVVGISASDIDSRLFEKVGSLYEQIQDHQEANQYYNEAYRINMSDIGIASSIGSYYIKLQATERALFYYERAV 700
Cdd:COG5010   36 NTKEDELAAAGRDKLAKAFAIESPSDNLYNKLGDFEESLALLEQALQLDPNNPELYYNLALLYSRSGDKDEAKEYYEKAL 115

                         90
                 ....*....|....
gi 281365345 701 LADPNDPNLMLRIA 714
Cdd:COG5010  116 ALSPDNPNAYSNLA 129
NlpI COG4785
Lipoprotein NlpI, contains TPR repeats [Cell wall/membrane/envelope biogenesis];
460-665 1.45e-04

Lipoprotein NlpI, contains TPR repeats [Cell wall/membrane/envelope biogenesis];


Pssm-ID: 443815 [Multi-domain]  Cd Length: 223  Bit Score: 44.14  E-value: 1.45e-04
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 281365345 460 YLRQNDVHQAIETLQMYDRKSEGSMTASALTNLSFIYISLGNLEMAshcVNQLHEIGSLK-NNAPGLINAGIVELGSHNL 538
Cdd:COG4785   47 ALAAAALAAAALAAERIDRALALPDLAQLYYERGVAYDSLGDYDLA---IADFDQALELDpDLAEAYNNRGLAYLLLGDY 123

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 281365345 539 ILASERFEGALQLQPMNFEARYNLGLVALAQNDYELAEERFEllkeqlmlpssvqhshVFYQLAKlqerrlesglisnFT 618
Cdd:COG4785  124 DAALEDFDRALELDPDYAYAYLNRGIALYYLGRYELAIADLE----------------KALELDP-------------ND 174

                        170       180       190       200
                 ....*....|....*....|....*....|....*....|....*..
gi 281365345 619 PGAALQAYLQVVGISASDIDSRLFEKVGSLYEQIQDHQEANQYYNEA 665
Cdd:COG4785  175 PERALWLYLAERKLDPEKALALLLEDWATAYLLQGDTEEARELFKLA 221
NrfG COG4235
Cytochrome c-type biogenesis protein CcmH/NrfG [Energy production and conversion, ...
 638-741 2.07e-04

Cytochrome c-type biogenesis protein CcmH/NrfG [Energy production and conversion, Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 443378 [Multi-domain]  Cd Length: 131  Bit Score: 41.92  E-value: 2.07e-04
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 281365345 638 DSRLFEKVGSLYEQIQDHQEANQYYNEAYRINMSDIGIASSIGSYYIKLQATERALFYYERAVLADPNDPNLMLRIASCf 717
Cdd:COG4235   16 DAEGWLLLGRAYLRLGRYDEALAAYEKALRLDPDNADALLDLAEALLAAGDTEEAEELLERALALDPDNPEALYLLGLA- 94

                         90       100
                 ....*....|....*....|....*..
gi 281365345 718 rnsYLPTKQY---LGLFQKIHARFPDN 741
Cdd:COG4235   95 ---AFQQGDYaeaIAAWQKLLALLPAD 118
TPR COG0457
Tetratricopeptide (TPR) repeat [General function prediction only];
183-316 2.91e-04

Tetratricopeptide (TPR) repeat [General function prediction only];


Pssm-ID: 440225 [Multi-domain]  Cd Length: 245  Bit Score: 43.46  E-value: 2.91e-04
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 281365345 183 YAVFFNLAEQYERSEMHIEALNTY--SImaknKMFPHVNQLKLNMGNIYYSMGIYQKAVKMYRMALDSVPKSlsqlrLKI 260
Cdd:COG0457    8 AEAYNNLGLAYRRLGRYEEAIEDYekAL----ELDPDDAEALYNLGLAYLRLGRYEEALADYEQALELDPDD-----AEA 78

                         90       100       110       120       130
                 ....*....|....*....|....*....|....*....|....*....|....*..
gi 281365345 261 RENIGILFIRMGSYSDAASSFE-FIMTERANIRSSIHLLLCYFALGDVEKVKLAFRR 316
Cdd:COG0457   79 LNNLGLALQALGRYEEALEDYDkALELDPDDAEALYNLGLALLELGRYDEAIEAYER 135
TadD COG5010
Flp pilus assembly protein TadD, contains TPR repeats [Intracellular trafficking, secretion, ...
 548-704 4.38e-04

Flp pilus assembly protein TadD, contains TPR repeats [Intracellular trafficking, secretion, and vesicular transport, Extracellular structures];


Pssm-ID: 444034 [Multi-domain]  Cd Length: 155  Bit Score: 41.48  E-value: 4.38e-04
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 281365345 548 ALQLQPMNFEARYNLGLVALAQNDYELAEERFELLKEQLMLPSSVQHSHVFYQLAKLQERRLEsglisnftpgAALQAYL 627
Cdd:COG5010    9 RLPLYLLLLTKLRTLVEKYEAALAGANNTKEDELAAAGRDKLAKAFAIESPSDNLYNKLGDFE----------ESLALLE 78

                         90       100       110       120       130       140       150
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 281365345 628 QVVGISASDIDSRLFekVGSLYEQIQDHQEANQYYNEAYRINMSDIGIASSIGSYYIKLQATERALFYYERAVLADP 704
Cdd:COG5010   79 QALQLDPNNPELYYN--LALLYSRSGDKDEAKEYYEKALALSPDNPNAYSNLAALLLSLGQDDEAKAALQRALGTSP 153
Spy COG3914
Predicted O-linked N-acetylglucosamine transferase, SPINDLY family [Posttranslational ...
 557-762 4.60e-04

Predicted O-linked N-acetylglucosamine transferase, SPINDLY family [Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 443119 [Multi-domain]  Cd Length: 658  Bit Score: 43.83  E-value: 4.60e-04
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 281365345 557 EARYNLGLVALAQNDYELAEERFELLKEQLMLPSSvqhshvFYQLAKLQERRLESGLISNFTPGAALQAYLQVVGISASD 636
Cdd:COG3914    2 AAAALLALAALAAAALLAAAAAAELALAAELEAAA------LAAALGLALLLLAALAEAAAAALLALAAGEAAAAAAALL 75

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 281365345 637 IDSRLFEKVGSLYEQIQDHQEANQYYNEAYRINMSDIGIASSIGSYYIKLQATERALFYYERAVLADPNDPNLMLRIASC 716
Cdd:COG3914   76 LLAALLELAALLLQALGRYEEALALYRRALALNPDNAEALFNLGNLLLALGRLEEALAALRRALALNPDFAEAYLNLGEA 155

                        170       180       190       200
                 ....*....|....*....|....*....|....*....|....*.
gi 281365345 717 FRNSYLPTkQYLGLFQKIHARFPDNLTCIRALMQVtkSLELGDLYE 762
Cdd:COG3914  156 LRRLGRLE-EAIAALRRALELDPDNAEALNNLGNA--LQDLGRLEE 198
PEP_TPR_lipo TIGR02917
putative PEP-CTERM system TPR-repeat lipoprotein; This protein family occurs in strictly ...
 451-710 6.29e-04

putative PEP-CTERM system TPR-repeat lipoprotein; This protein family occurs in strictly within a subset of Gram-negative bacterial species with the proposed PEP-CTERM/exosortase system, analogous to the LPXTG/sortase system common in Gram-positive bacteria. This protein occurs in a species if and only if a transmembrane histidine kinase (TIGR02916) and a DNA-binding response regulator (TIGR02915) also occur. The present of tetratricopeptide repeats (TPR) suggests protein-protein interaction, possibly for the regulation of PEP-CTERM protein expression, since many PEP-CTERM proteins in these genomes are preceded by a proposed DNA binding site for the response regulator.


Pssm-ID: 274350 [Multi-domain]  Cd Length: 899  Bit Score: 43.53  E-value: 6.29e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 281365345  451 ELELNKALV--YLRQNDVHQAIETLQ-MYDRKSEgsmTASALTNLSFIYISLGNLEMASHCVNQLHEIGSlkNNAPGLIN 527
Cdd:TIGR02917 566 EIEPALALAqyYLGKGQLKKALAILNeAADAAPD---SPEAWLMLGRAQLAAGDLNKAVSSFKKLLALQP--DSALALLL 640

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 281365345  528 AGIVELGSHNLILASERFEGALQLQPMNFEARYNLGLVALAQNDYELAEERFELLKEQLM------------------LP 589
Cdd:TIGR02917 641 LADAYAVMKNYAKAITSLKRALELKPDNTEAQIGLAQLLLAAKRTESAKKIAKSLQKQHPkaalgfelegdlylrqkdYP 720

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 281365345  590 SSVQHSHVFYQLAKLQER--RLESGLISNFTPGAALQAYLQVVGISASDIDSRLFekVGSLYEQIQDHQEANQYYNEAYR 667
Cdd:TIGR02917 721 AAIQAYRKALKRAPSSQNaiKLHRALLASGNTAEAVKTLEAWLKTHPNDAVLRTA--LAELYLAQKDYDKAIKHYQTVVK 798

                         250       260       270       280
                  ....*....|....*....|....*....|....*....|...
gi 281365345  668 INMSDIGIASSIGSYYIKLQATeRALFYYERAVLADPNDPNLM 710
Cdd:TIGR02917 799 KAPDNAVVLNNLAWLYLELKDP-RALEYAERALKLAPNIPAIL 840
NrfG COG4235
Cytochrome c-type biogenesis protein CcmH/NrfG [Energy production and conversion, ...
 543-669 8.03e-04

Cytochrome c-type biogenesis protein CcmH/NrfG [Energy production and conversion, Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 443378 [Multi-domain]  Cd Length: 131  Bit Score: 40.37  E-value: 8.03e-04
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 281365345 543 ERFEGALQLQPMNFEARYNLGLVALAQNDYELAEERFE-LLKeqlMLPSSVQhshVFYQLAKLQERRLEsglisnftPGA 621
Cdd:COG4235    4 ARLRQALAANPNDAEGWLLLGRAYLRLGRYDEALAAYEkALR---LDPDNAD---ALLDLAEALLAAGD--------TEE 69

                         90       100       110       120
                 ....*....|....*....|....*....|....*....|....*...
gi 281365345 622 ALQAYLQVVGISASDIDSRLFekVGSLYEQIQDHQEANQYYNEAYRIN 669
Cdd:COG4235   70 AEELLERALALDPDNPEALYL--LGLAAFQQGDYAEAIAAWQKLLALL 115
LapB COG2956
Lipopolysaccharide biosynthesis regulator YciM/LapB, contains six TPR domains and a C-terminal ...
 182-317 9.01e-04

Lipopolysaccharide biosynthesis regulator YciM/LapB, contains six TPR domains and a C-terminal metal-binding domain [Cell wall/membrane/envelope biogenesis];


Pssm-ID: 442196 [Multi-domain]  Cd Length: 275  Bit Score: 42.02  E-value: 9.01e-04
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 281365345 182 TYAVFFNLAEQYERSEMHIEALNTY-SIMAKNkmfPHVNQLKLNMGNIYYSMGIYQKAVKMYRMALDSVPKSLSQLRLKI 260
Cdd:COG2956   41 TVEAHLALGNLYRRRGEYDRAIRIHqKLLERD---PDRAEALLELAQDYLKAGLLDRAEELLEKLLELDPDDAEALRLLA 117

                         90       100       110       120       130
                 ....*....|....*....|....*....|....*....|....*....|....*....
gi 281365345 261 RenigiLFIRMGSYSDAASSFEfIMTERANIRSSIHLLL--CYFALGDVEKVKLAFRRL 317
Cdd:COG2956  118 E-----IYEQEGDWEKAIEVLE-RLLKLGPENAHAYCELaeLYLEQGDYDEAIEALEKA 170
PilF COG3063
Type IV pilus assembly protein PilF/PilW [Cell motility, Extracellular structures];
648-714 1.68e-03

Type IV pilus assembly protein PilF/PilW [Cell motility, Extracellular structures];


Pssm-ID: 442297 [Multi-domain]  Cd Length: 94  Bit Score: 38.61  E-value: 1.68e-03
                         10        20        30        40        50        60
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 281365345 648 LYEQIQDHQEANQYYNEAYRINMSDIGIASSIGSYYIKLQATERALfYYERAVLADPNDPNLMLRIA 714
Cdd:COG3063    1 LYLKLGDLEEAEEYYEKALELDPDNADALNNLGLLLLEQGRYDEAI-ALEKALKLDPNNAEALLNLA 66
LapB COG2956
Lipopolysaccharide biosynthesis regulator YciM/LapB, contains six TPR domains and a C-terminal ...
 183-326 2.89e-03

Lipopolysaccharide biosynthesis regulator YciM/LapB, contains six TPR domains and a C-terminal metal-binding domain [Cell wall/membrane/envelope biogenesis];


Pssm-ID: 442196 [Multi-domain]  Cd Length: 275  Bit Score: 40.48  E-value: 2.89e-03
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 281365345 183 YAVFFNLAEQYERSEMHIEALNTYSIMAKNKmfPHVNQLKLNMGNIYYSMGIYQKAVKMYRMALDSVPKSLsqlrlKIRE 262
Cdd:COG2956   76 AEALLELAQDYLKAGLLDRAEELLEKLLELD--PDDAEALRLLAEIYEQEGDWEKAIEVLERLLKLGPENA-----HAYC 148

                         90       100       110       120       130       140
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 281365345 263 NIGILFIRMGSYSDAASSFEF-IMTERANIRSSIHLLLCYFALGDVEKVKLAFRRLCDVQTEAIE 326
Cdd:COG2956  149 ELAELYLEQGDYDEAIEALEKaLKLDPDCARALLLLAELYLEQGDYEEAIAALERALEQDPDYLP 213
PilF COG3063
Type IV pilus assembly protein PilF/PilW [Cell motility, Extracellular structures];
536-608 3.39e-03

Type IV pilus assembly protein PilF/PilW [Cell motility, Extracellular structures];


Pssm-ID: 442297 [Multi-domain]  Cd Length: 94  Bit Score: 37.46  E-value: 3.39e-03
                         10        20        30        40        50        60        70
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 281365345 536 HNLILASERFEGALQLQPMNFEARYNLGLVALAQNDYELAEERFELLKEQlmlpssVQHSHVFYQLAKLQERR 608
Cdd:COG3063    6 GDLEEAEEYYEKALELDPDNADALNNLGLLLLEQGRYDEAIALEKALKLD------PNNAEALLNLAELLLEL 72
NrfG COG4235
Cytochrome c-type biogenesis protein CcmH/NrfG [Energy production and conversion, ...
 520-580 4.02e-03

Cytochrome c-type biogenesis protein CcmH/NrfG [Energy production and conversion, Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 443378 [Multi-domain]  Cd Length: 131  Bit Score: 38.45  E-value: 4.02e-03
                         10        20        30        40        50        60
                 ....*....|....*....|....*....|....*....|....*....|....*....|.
gi 281365345 520 NNAPGLINAGIVELGSHNLILASERFEGALQLQPMNFEARYNLGLVALAQNDYELAEERFE 580
Cdd:COG4235   15 NDAEGWLLLGRAYLRLGRYDEALAAYEKALRLDPDNADALLDLAEALLAAGDTEEAEELLE 75
TPR smart00028
Tetratricopeptide repeats; Repeats present in 4 or more copies in proteins. Contain a minimum ...
 223-251 5.44e-03

Tetratricopeptide repeats; Repeats present in 4 or more copies in proteins. Contain a minimum of 34 amino acids each and self-associate via a "knobs and holes" mechanism.


Pssm-ID: 197478 [Multi-domain]  Cd Length: 34  Bit Score: 35.11  E-value: 5.44e-03
                           10        20
                   ....*....|....*....|....*....
gi 281365345   223 LNMGNIYYSMGIYQKAVKMYRMALDSVPK 251
Cdd:smart00028   5 YNLGNAYLKLGDYDEALEYYEKALELDPN 33
TPR_1 pfam00515
Tetratricopeptide repeat;
224-247 7.74e-03

Tetratricopeptide repeat;


Pssm-ID: 459840 [Multi-domain]  Cd Length: 34  Bit Score: 34.70  E-value: 7.74e-03
                          10        20
                  ....*....|....*....|....
gi 281365345  224 NMGNIYYSMGIYQKAVKMYRMALD 247
Cdd:pfam00515   6 NLGNAYFKLGKYDEALEYYEKALE 29
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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