NCBI Home Page NCBI Site Search page NCBI Guide that lists and describes the NCBI resources
Conserved domains on  [gi|21539655|ref|NP_598462|]
View 

pre-mRNA-processing factor 6 [Mus musculus]

Protein Classification

pre-mRNA-processing factor 6 family protein( domain architecture ID 13720877)

pre-mRNA-processing factor 6 (PRPF6) family protein similar to human PRPF6 that is involved in pre-mRNA splicing as a component of the U4/U6-U5 tri-snRNP complex, one of the building blocks of the spliceosome

Graphical summary

 Zoom to residue level

show extra options »

Show site features     Horizontal zoom: ×

List of domain hits

 Name Accession Description Interval E-value
PRP1_N pfam06424
PRP1 splicing factor, N-terminal; This domain is specific to the N-terminal part of the prp1 ...
 13-169 1.16e-48

PRP1 splicing factor, N-terminal; This domain is specific to the N-terminal part of the prp1 splicing factor, which is involved in mRNA splicing (and possibly also poly(A)+ RNA nuclear export and cell cycle progression). This domain is specific to the N terminus of the RNA splicing factor encoded by prp1. It is involved in mRNA splicing and possibly also poly(A)and RNA nuclear export and cell cycle progression.


:

Pssm-ID: 461908  Cd Length: 109  Bit Score: 167.70  E-value: 1.16e-48
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 21539655    13 APLGYVPGLGRGATGFTTrsdigpardandpvddrhappgkrtvgdqmkknqaaddddedlndtnyDEFNGYAGSLFSSG 92
Cdd:pfam06424   1 APPGYVAGLGRGATGFTT------------------------------------------------DEFEGYDGGLFAGG 32

                          90       100       110       120       130       140       150
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 21539655    93 PYEKDDEEADAIYAALDKRMDERRKERREQREKEEIEKYRMERPKIQQQFSDLKRKLAEVTEEEWLSIPEVGDARNK 169
Cdd:pfam06424  33 PYDKDDEEADRIYEAIDERMDERRKKRREAREKEELEKYRAERPKIQQQFADLKRGLATVSEEEWANIPEVGDLTRK 109
LapB COG2956
Lipopolysaccharide biosynthesis regulator YciM/LapB, contains six TPR domains and a C-terminal ...
 654-899 2.58e-16

Lipopolysaccharide biosynthesis regulator YciM/LapB, contains six TPR domains and a C-terminal metal-binding domain [Cell wall/membrane/envelope biogenesis];


:

Pssm-ID: 442196 [Multi-domain]  Cd Length: 275  Bit Score: 80.16  E-value: 2.58e-16
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 21539655 654 ENNEYERARRLLAKARSSAP-TARVFMKSVKLEWVLGNISAAQELCEEALRHYEDFPKLWMMKGQIEEQGELMEKAREAY 732
Cdd:COG2956  20 LNGQPDKAIDLLEEALELDPeTVEAHLALGNLYRRRGEYDRAIRIHQKLLERDPDRAEALLELAQDYLKAGLLDRAEELL 99

                        90       100       110       120       130       140       150       160
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 21539655 733 NQGLKKCPHSTPLWLLLSRLEEKIGQLTRARAILEKSRLKNPKNPGLWLESVRLEYRAGLKNIANTLMAKALQECPNSGI 812
Cdd:COG2956 100 EKLLELDPDDAEALRLLAEIYEQEGDWEKAIEVLERLLKLGPENAHAYCELAELYLEQGDYDEAIEALEKALKLDPDCAR 179

                       170       180       190       200       210       220       230       240
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 21539655 813 LWSEAVFLEARPQRKTKSVDALKKC-EHDP---HVLLAVAKLFWSERKITKAREWFHRTVKIDSDLGDAWAFFYKFELQH 888
Cdd:COG2956 180 ALLLLAELYLEQGDYEEAIAALERAlEQDPdylPALPRLAELYEKLGDPEEALELLRKALELDPSDDLLLALADLLERKE 259

                       250
                ....*....|.
gi 21539655 889 GTEEQQEEVRK 899
Cdd:COG2956 260 GLEAALALLER 270
PEP_TPR_lipo super family cl37187
putative PEP-CTERM system TPR-repeat lipoprotein; This protein family occurs in strictly ...
 290-806 9.09e-12

putative PEP-CTERM system TPR-repeat lipoprotein; This protein family occurs in strictly within a subset of Gram-negative bacterial species with the proposed PEP-CTERM/exosortase system, analogous to the LPXTG/sortase system common in Gram-positive bacteria. This protein occurs in a species if and only if a transmembrane histidine kinase (TIGR02916) and a DNA-binding response regulator (TIGR02915) also occur. The present of tetratricopeptide repeats (TPR) suggests protein-protein interaction, possibly for the regulation of PEP-CTERM protein expression, since many PEP-CTERM proteins in these genomes are preceded by a proposed DNA binding site for the response regulator.


The actual alignment was detected with superfamily member TIGR02917:

Pssm-ID: 274350 [Multi-domain]  Cd Length: 899  Bit Score: 69.34  E-value: 9.09e-12
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 21539655   290 DIKKARLLLKSVRETNPHHPPAWIASARLEEVTGKLQVARNLIMKGTEMCPKSEDVWLEAARLQ----PGDTAKAVVAQA 365
Cdd:TIGR02917 140 QLELAQKSYEQALAIDPRSLYAKLGLAQLALAENRFDEARALIDEVLTADPGNVDALLLKGDLLlslgNIELALAAYRKA 219

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 21539655   366 VRHLPQSVRIYIRAA----ELETDIRAKKRvLRKALEHVPNS--VRLWKAAVELEEP--EDARIMLSRAVECCPTSVELW 437
Cdd:TIGR02917 220 IALRPNNIAVLLALAtiliEAGEFEEAEKH-ADALLKKAPNSplAHYLKALVDFQKKnyEDARETLQDALKSAPEYLPAL 298

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 21539655   438 L----ALARLETYENARKVLNKARENIPTDrhiwITAAKLEEAngnTQMVEKIIDRAITSL-RANGVE------------ 500
Cdd:TIGR02917 299 LlagaSEYQLGNLEQAYQYLNQILKYAPNS----HQARRLLAS---IQLRLGRVDEAIATLsPALGLDpddpaalsllge 371

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 21539655   501 --INREQWIQDAEECDRAGSVATCQAVMRAVIGIG--------IEEEDRKHTWMEDADSCVAHNAL----------ECAR 560
Cdd:TIGR02917 372 ayLALGDFEKAAEYLAKATELDPENAAARTQLGISklsqgdpsEAIADLETAAQLDPELGRADLLLilsylrsgqfDKAL 451

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 21539655   561 AIYAYALQVFPSKKSVW--LRAAYFEKNH--GTRESLEALLQRAVAHCPKAEVLWLMGAKskwlAGDVPAARSILALAFQ 636
Cdd:TIGR02917 452 AAAKKLEKKQPDNASLHnlLGAIYLGKGDlaKAREAFEKALSIEPDFFPAAANLARIDIQ----EGNPDDAIQRFEKVLT 527

                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 21539655   637 ANPNSEEIWLAAVKLESENNEYERARRLLAKARSSAPTA---RVFMKSVKLEwvLGNISAAQELCEEALRHYEDFPKLWM 713
Cdd:TIGR02917 528 IDPKNLRAILALAGLYLRTGNEEEAVAWLEKAAELNPQEiepALALAQYYLG--KGQLKKALAILNEAADAAPDSPEAWL 605

                         490       500       510       520       530       540       550       560
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 21539655   714 MKGQIEEQGELMEKAREAYNQGLKKCPHSTPLWLLLSRLEEKIGQLTRARAILEKSRLKNPKNPGLWLESVRLEYRAGLK 793
Cdd:TIGR02917 606 MLGRAQLAAGDLNKAVSSFKKLLALQPDSALALLLLADAYAVMKNYAKAITSLKRALELKPDNTEAQIGLAQLLLAAKRT 685

                         570
                  ....*....|...
gi 21539655   794 NIANTLmAKALQE 806
Cdd:TIGR02917 686 ESAKKI-AKSLQK 697
 
Name Accession Description Interval E-value
PRP1_N pfam06424
PRP1 splicing factor, N-terminal; This domain is specific to the N-terminal part of the prp1 ...
 13-169 1.16e-48

PRP1 splicing factor, N-terminal; This domain is specific to the N-terminal part of the prp1 splicing factor, which is involved in mRNA splicing (and possibly also poly(A)+ RNA nuclear export and cell cycle progression). This domain is specific to the N terminus of the RNA splicing factor encoded by prp1. It is involved in mRNA splicing and possibly also poly(A)and RNA nuclear export and cell cycle progression.


Pssm-ID: 461908  Cd Length: 109  Bit Score: 167.70  E-value: 1.16e-48
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 21539655    13 APLGYVPGLGRGATGFTTrsdigpardandpvddrhappgkrtvgdqmkknqaaddddedlndtnyDEFNGYAGSLFSSG 92
Cdd:pfam06424   1 APPGYVAGLGRGATGFTT------------------------------------------------DEFEGYDGGLFAGG 32

                          90       100       110       120       130       140       150
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 21539655    93 PYEKDDEEADAIYAALDKRMDERRKERREQREKEEIEKYRMERPKIQQQFSDLKRKLAEVTEEEWLSIPEVGDARNK 169
Cdd:pfam06424  33 PYDKDDEEADRIYEAIDERMDERRKKRREAREKEELEKYRAERPKIQQQFADLKRGLATVSEEEWANIPEVGDLTRK 109
LapB COG2956
Lipopolysaccharide biosynthesis regulator YciM/LapB, contains six TPR domains and a C-terminal ...
 654-899 2.58e-16

Lipopolysaccharide biosynthesis regulator YciM/LapB, contains six TPR domains and a C-terminal metal-binding domain [Cell wall/membrane/envelope biogenesis];


Pssm-ID: 442196 [Multi-domain]  Cd Length: 275  Bit Score: 80.16  E-value: 2.58e-16
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 21539655 654 ENNEYERARRLLAKARSSAP-TARVFMKSVKLEWVLGNISAAQELCEEALRHYEDFPKLWMMKGQIEEQGELMEKAREAY 732
Cdd:COG2956  20 LNGQPDKAIDLLEEALELDPeTVEAHLALGNLYRRRGEYDRAIRIHQKLLERDPDRAEALLELAQDYLKAGLLDRAEELL 99

                        90       100       110       120       130       140       150       160
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 21539655 733 NQGLKKCPHSTPLWLLLSRLEEKIGQLTRARAILEKSRLKNPKNPGLWLESVRLEYRAGLKNIANTLMAKALQECPNSGI 812
Cdd:COG2956 100 EKLLELDPDDAEALRLLAEIYEQEGDWEKAIEVLERLLKLGPENAHAYCELAELYLEQGDYDEAIEALEKALKLDPDCAR 179

                       170       180       190       200       210       220       230       240
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 21539655 813 LWSEAVFLEARPQRKTKSVDALKKC-EHDP---HVLLAVAKLFWSERKITKAREWFHRTVKIDSDLGDAWAFFYKFELQH 888
Cdd:COG2956 180 ALLLLAELYLEQGDYEEAIAALERAlEQDPdylPALPRLAELYEKLGDPEEALELLRKALELDPSDDLLLALADLLERKE 259

                       250
                ....*....|.
gi 21539655 889 GTEEQQEEVRK 899
Cdd:COG2956 260 GLEAALALLER 270
PEP_TPR_lipo TIGR02917
putative PEP-CTERM system TPR-repeat lipoprotein; This protein family occurs in strictly ...
 290-806 9.09e-12

putative PEP-CTERM system TPR-repeat lipoprotein; This protein family occurs in strictly within a subset of Gram-negative bacterial species with the proposed PEP-CTERM/exosortase system, analogous to the LPXTG/sortase system common in Gram-positive bacteria. This protein occurs in a species if and only if a transmembrane histidine kinase (TIGR02916) and a DNA-binding response regulator (TIGR02915) also occur. The present of tetratricopeptide repeats (TPR) suggests protein-protein interaction, possibly for the regulation of PEP-CTERM protein expression, since many PEP-CTERM proteins in these genomes are preceded by a proposed DNA binding site for the response regulator.


Pssm-ID: 274350 [Multi-domain]  Cd Length: 899  Bit Score: 69.34  E-value: 9.09e-12
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 21539655   290 DIKKARLLLKSVRETNPHHPPAWIASARLEEVTGKLQVARNLIMKGTEMCPKSEDVWLEAARLQ----PGDTAKAVVAQA 365
Cdd:TIGR02917 140 QLELAQKSYEQALAIDPRSLYAKLGLAQLALAENRFDEARALIDEVLTADPGNVDALLLKGDLLlslgNIELALAAYRKA 219

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 21539655   366 VRHLPQSVRIYIRAA----ELETDIRAKKRvLRKALEHVPNS--VRLWKAAVELEEP--EDARIMLSRAVECCPTSVELW 437
Cdd:TIGR02917 220 IALRPNNIAVLLALAtiliEAGEFEEAEKH-ADALLKKAPNSplAHYLKALVDFQKKnyEDARETLQDALKSAPEYLPAL 298

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 21539655   438 L----ALARLETYENARKVLNKARENIPTDrhiwITAAKLEEAngnTQMVEKIIDRAITSL-RANGVE------------ 500
Cdd:TIGR02917 299 LlagaSEYQLGNLEQAYQYLNQILKYAPNS----HQARRLLAS---IQLRLGRVDEAIATLsPALGLDpddpaalsllge 371

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 21539655   501 --INREQWIQDAEECDRAGSVATCQAVMRAVIGIG--------IEEEDRKHTWMEDADSCVAHNAL----------ECAR 560
Cdd:TIGR02917 372 ayLALGDFEKAAEYLAKATELDPENAAARTQLGISklsqgdpsEAIADLETAAQLDPELGRADLLLilsylrsgqfDKAL 451

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 21539655   561 AIYAYALQVFPSKKSVW--LRAAYFEKNH--GTRESLEALLQRAVAHCPKAEVLWLMGAKskwlAGDVPAARSILALAFQ 636
Cdd:TIGR02917 452 AAAKKLEKKQPDNASLHnlLGAIYLGKGDlaKAREAFEKALSIEPDFFPAAANLARIDIQ----EGNPDDAIQRFEKVLT 527

                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 21539655   637 ANPNSEEIWLAAVKLESENNEYERARRLLAKARSSAPTA---RVFMKSVKLEwvLGNISAAQELCEEALRHYEDFPKLWM 713
Cdd:TIGR02917 528 IDPKNLRAILALAGLYLRTGNEEEAVAWLEKAAELNPQEiepALALAQYYLG--KGQLKKALAILNEAADAAPDSPEAWL 605

                         490       500       510       520       530       540       550       560
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 21539655   714 MKGQIEEQGELMEKAREAYNQGLKKCPHSTPLWLLLSRLEEKIGQLTRARAILEKSRLKNPKNPGLWLESVRLEYRAGLK 793
Cdd:TIGR02917 606 MLGRAQLAAGDLNKAVSSFKKLLALQPDSALALLLLADAYAVMKNYAKAITSLKRALELKPDNTEAQIGLAQLLLAAKRT 685

                         570
                  ....*....|...
gi 21539655   794 NIANTLmAKALQE 806
Cdd:TIGR02917 686 ESAKKI-AKSLQK 697
LapB COG2956
Lipopolysaccharide biosynthesis regulator YciM/LapB, contains six TPR domains and a C-terminal ...
 289-456 2.85e-11

Lipopolysaccharide biosynthesis regulator YciM/LapB, contains six TPR domains and a C-terminal metal-binding domain [Cell wall/membrane/envelope biogenesis];


Pssm-ID: 442196 [Multi-domain]  Cd Length: 275  Bit Score: 65.14  E-value: 2.85e-11
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 21539655 289 NDIKKARLLLKSVRETNPHHPPAWIASARLEEVTGKLQVARNLIMKGTEMCPKSEDVWLEAAR--LQPGDTAKAVVA--Q 364
Cdd:COG2956  90 GLLDRAEELLEKLLELDPDDAEALRLLAEIYEQEGDWEKAIEVLERLLKLGPENAHAYCELAElyLEQGDYDEAIEAleK 169

                        90       100       110       120       130       140       150       160
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 21539655 365 AVRHLPQSVRIYIRAAELET---DIRAKKRVLRKALEHVPNSV----RLWKAAVELEEPEDARIMLSRAVECCPtSVELW 437
Cdd:COG2956 170 ALKLDPDCARALLLLAELYLeqgDYEEAIAALERALEQDPDYLpalpRLAELYEKLGDPEEALELLRKALELDP-SDDLL 248

                       170       180
                ....*....|....*....|...
gi 21539655 438 LALARL----ETYENARKVLNKA 456
Cdd:COG2956 249 LALADLlerkEGLEAALALLERQ 271
PEP_TPR_lipo TIGR02917
putative PEP-CTERM system TPR-repeat lipoprotein; This protein family occurs in strictly ...
 556-813 1.49e-08

putative PEP-CTERM system TPR-repeat lipoprotein; This protein family occurs in strictly within a subset of Gram-negative bacterial species with the proposed PEP-CTERM/exosortase system, analogous to the LPXTG/sortase system common in Gram-positive bacteria. This protein occurs in a species if and only if a transmembrane histidine kinase (TIGR02916) and a DNA-binding response regulator (TIGR02915) also occur. The present of tetratricopeptide repeats (TPR) suggests protein-protein interaction, possibly for the regulation of PEP-CTERM protein expression, since many PEP-CTERM proteins in these genomes are preceded by a proposed DNA binding site for the response regulator.


Pssm-ID: 274350 [Multi-domain]  Cd Length: 899  Bit Score: 58.94  E-value: 1.49e-08
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 21539655   556 LECARAIYAYALQVFPSKKSVWLRAAYFEKNHGTRESLEALLQRAVAHCPKAEVLWLMGAKSKWLAGDVPAARSILALAF 635
Cdd:TIGR02917 141 LELAQKSYEQALAIDPRSLYAKLGLAQLALAENRFDEARALIDEVLTADPGNVDALLLKGDLLLSLGNIELALAAYRKAI 220

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 21539655   636 QANPNSEEIWLAAVKLESENNEYERARR----LLAKARSSaPTARvFMKSVkLEWVLGNISAAQELCEEALRHYEDFPKL 711
Cdd:TIGR02917 221 ALRPNNIAVLLALATILIEAGEFEEAEKhadaLLKKAPNS-PLAH-YLKAL-VDFQKKNYEDARETLQDALKSAPEYLPA 297

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 21539655   712 WMMKGQIEEQGELMEKAREAYNQGLKKCPHSTPLWLLLSRLEEKIGQLTRARAILEKSRLKNPKNPGLwLESVRLEY-RA 790
Cdd:TIGR02917 298 LLLAGASEYQLGNLEQAYQYLNQILKYAPNSHQARRLLASIQLRLGRVDEAIATLSPALGLDPDDPAA-LSLLGEAYlAL 376

                         250       260
                  ....*....|....*....|...
gi 21539655   791 GLKNIANTLMAKALQECPNSGIL 813
Cdd:TIGR02917 377 GDFEKAAEYLAKATELDPENAAA 399
PRK11788 PRK11788
tetratricopeptide repeat protein; Provisional
 352-494 2.38e-04

tetratricopeptide repeat protein; Provisional


Pssm-ID: 236983 [Multi-domain]  Cd Length: 389  Bit Score: 44.41  E-value: 2.38e-04
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 21539655  352 LQPGDTAKAV--VAQAVRHLPQSVR-------IYIRAAELETDIRAKKRVLRKALEHVPNSV-RLWKAAVELEEPEDARI 421
Cdd:PRK11788 191 LARGDLDAARalLKKALAADPQCVRasillgdLALAQGDYAAAIEALERVEEQDPEYLSEVLpKLMECYQALGDEAEGLE 270

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 21539655  422 MLSRAVECCPtSVELWLALAR-LETYENARKVLNKARENI---PTDR--HIWITAAKLEEANGNT----QMVEKIIDRAI 491
Cdd:PRK11788 271 FLRRALEEYP-GADLLLALAQlLEEQEGPEAAQALLREQLrrhPSLRgfHRLLDYHLAEAEEGRAkeslLLLRDLVGEQL 349


                 ...
gi 21539655  492 TSL 494
Cdd:PRK11788 350 KRK 352
ACL4-like cd24142
Assembly chaperone of ribosomal protein L4 and similar proteins; Assembly chaperone of RPL4 ...
 393-524 2.43e-04

Assembly chaperone of ribosomal protein L4 and similar proteins; Assembly chaperone of RPL4 (ACL4) acts as a chaperone for the L4 ribosomal subunit, encoded by RPL4A and RPL4B, and is required for hierarchical ribosome assembly. It is required for the soluble expression of newly synthesized RPL4 and for the protection of RPL4 from the Tom1-dependent cellular degradation machinery. ACL4 shields ribosomal protein L4 until timely release and insertion into the pre-ribosome is possible, once ribosomal protein L18 is present.


Pssm-ID: 467942 [Multi-domain]  Cd Length: 306  Bit Score: 44.16  E-value: 2.43e-04
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 21539655 393 LRKALEHVPNSVRLWKAA----VELEEPEDARIMLSRAVECCPT-SVELWLALARLETYENARKVLNKARENIptDRHIW 467
Cdd:cd24142  23 LQRALELEPNNVEALELLgeilLELGDVEEAREVLLRAIELDPDgGYEKYLYLGQLSGGEEALQYYEKGIEIL--EEELQ 100

                        90       100       110       120       130
                ....*....|....*....|....*....|....*....|....*....|....*..
gi 21539655 468 ITAAKLEEANGNTQMVEKIIDRAITSLrangveinREQWIQDAeeCDRAGSVATCQA 524
Cdd:cd24142 101 ALQAASAEAEEEAEELKRKLSSALCAL--------AEIYMTDL--CDEPDAEQRCEE 147
TPR_19 pfam14559
Tetratricopeptide repeat;
621-673 5.06e-04

Tetratricopeptide repeat;


Pssm-ID: 434038 [Multi-domain]  Cd Length: 65  Bit Score: 39.10  E-value: 5.06e-04
                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|...
gi 21539655   621 AGDVPAARSILALAFQANPNSEEIWLAAVKLESENNEYERARRLLAKARSSAP 673
Cdd:pfam14559   1 EGDYAEALELLEQALAEDPDNAEARLGLAEALLALGRLDEAEALLAALPAADP 53
HAT smart00386
HAT (Half-A-TPR) repeats; Present in several RNA-binding proteins. Structurally and ...
 444-476 1.61e-03

HAT (Half-A-TPR) repeats; Present in several RNA-binding proteins. Structurally and sequentially thought to be similar to TPRs.


Pssm-ID: 214642 [Multi-domain]  Cd Length: 33  Bit Score: 36.76  E-value: 1.61e-03
                           10        20        30
                   ....*....|....*....|....*....|...
gi 21539655    444 ETYENARKVLNKARENIPTDRHIWITAAKLEEA 476
Cdd:smart00386   1 GDIERARKIYERALEKFPKSVELWLKYAEFEER 33
HAT smart00386
HAT (Half-A-TPR) repeats; Present in several RNA-binding proteins. Structurally and ...
 725-755 1.83e-03

HAT (Half-A-TPR) repeats; Present in several RNA-binding proteins. Structurally and sequentially thought to be similar to TPRs.


Pssm-ID: 214642 [Multi-domain]  Cd Length: 33  Bit Score: 36.76  E-value: 1.83e-03
                           10        20        30
                   ....*....|....*....|....*....|.
gi 21539655    725 MEKAREAYNQGLKKCPHSTPLWLLLSRLEEK 755
Cdd:smart00386   3 IERARKIYERALEKFPKSVELWLKYAEFEER 33
 
Name Accession Description Interval E-value
PRP1_N pfam06424
PRP1 splicing factor, N-terminal; This domain is specific to the N-terminal part of the prp1 ...
 13-169 1.16e-48

PRP1 splicing factor, N-terminal; This domain is specific to the N-terminal part of the prp1 splicing factor, which is involved in mRNA splicing (and possibly also poly(A)+ RNA nuclear export and cell cycle progression). This domain is specific to the N terminus of the RNA splicing factor encoded by prp1. It is involved in mRNA splicing and possibly also poly(A)and RNA nuclear export and cell cycle progression.


Pssm-ID: 461908  Cd Length: 109  Bit Score: 167.70  E-value: 1.16e-48
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 21539655    13 APLGYVPGLGRGATGFTTrsdigpardandpvddrhappgkrtvgdqmkknqaaddddedlndtnyDEFNGYAGSLFSSG 92
Cdd:pfam06424   1 APPGYVAGLGRGATGFTT------------------------------------------------DEFEGYDGGLFAGG 32

                          90       100       110       120       130       140       150
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 21539655    93 PYEKDDEEADAIYAALDKRMDERRKERREQREKEEIEKYRMERPKIQQQFSDLKRKLAEVTEEEWLSIPEVGDARNK 169
Cdd:pfam06424  33 PYDKDDEEADRIYEAIDERMDERRKKRREAREKEELEKYRAERPKIQQQFADLKRGLATVSEEEWANIPEVGDLTRK 109
LapB COG2956
Lipopolysaccharide biosynthesis regulator YciM/LapB, contains six TPR domains and a C-terminal ...
 654-899 2.58e-16

Lipopolysaccharide biosynthesis regulator YciM/LapB, contains six TPR domains and a C-terminal metal-binding domain [Cell wall/membrane/envelope biogenesis];


Pssm-ID: 442196 [Multi-domain]  Cd Length: 275  Bit Score: 80.16  E-value: 2.58e-16
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 21539655 654 ENNEYERARRLLAKARSSAP-TARVFMKSVKLEWVLGNISAAQELCEEALRHYEDFPKLWMMKGQIEEQGELMEKAREAY 732
Cdd:COG2956  20 LNGQPDKAIDLLEEALELDPeTVEAHLALGNLYRRRGEYDRAIRIHQKLLERDPDRAEALLELAQDYLKAGLLDRAEELL 99

                        90       100       110       120       130       140       150       160
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 21539655 733 NQGLKKCPHSTPLWLLLSRLEEKIGQLTRARAILEKSRLKNPKNPGLWLESVRLEYRAGLKNIANTLMAKALQECPNSGI 812
Cdd:COG2956 100 EKLLELDPDDAEALRLLAEIYEQEGDWEKAIEVLERLLKLGPENAHAYCELAELYLEQGDYDEAIEALEKALKLDPDCAR 179

                       170       180       190       200       210       220       230       240
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 21539655 813 LWSEAVFLEARPQRKTKSVDALKKC-EHDP---HVLLAVAKLFWSERKITKAREWFHRTVKIDSDLGDAWAFFYKFELQH 888
Cdd:COG2956 180 ALLLLAELYLEQGDYEEAIAALERAlEQDPdylPALPRLAELYEKLGDPEEALELLRKALELDPSDDLLLALADLLERKE 259

                       250
                ....*....|.
gi 21539655 889 GTEEQQEEVRK 899
Cdd:COG2956 260 GLEAALALLER 270
PEP_TPR_lipo TIGR02917
putative PEP-CTERM system TPR-repeat lipoprotein; This protein family occurs in strictly ...
 290-806 9.09e-12

putative PEP-CTERM system TPR-repeat lipoprotein; This protein family occurs in strictly within a subset of Gram-negative bacterial species with the proposed PEP-CTERM/exosortase system, analogous to the LPXTG/sortase system common in Gram-positive bacteria. This protein occurs in a species if and only if a transmembrane histidine kinase (TIGR02916) and a DNA-binding response regulator (TIGR02915) also occur. The present of tetratricopeptide repeats (TPR) suggests protein-protein interaction, possibly for the regulation of PEP-CTERM protein expression, since many PEP-CTERM proteins in these genomes are preceded by a proposed DNA binding site for the response regulator.


Pssm-ID: 274350 [Multi-domain]  Cd Length: 899  Bit Score: 69.34  E-value: 9.09e-12
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 21539655   290 DIKKARLLLKSVRETNPHHPPAWIASARLEEVTGKLQVARNLIMKGTEMCPKSEDVWLEAARLQ----PGDTAKAVVAQA 365
Cdd:TIGR02917 140 QLELAQKSYEQALAIDPRSLYAKLGLAQLALAENRFDEARALIDEVLTADPGNVDALLLKGDLLlslgNIELALAAYRKA 219

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 21539655   366 VRHLPQSVRIYIRAA----ELETDIRAKKRvLRKALEHVPNS--VRLWKAAVELEEP--EDARIMLSRAVECCPTSVELW 437
Cdd:TIGR02917 220 IALRPNNIAVLLALAtiliEAGEFEEAEKH-ADALLKKAPNSplAHYLKALVDFQKKnyEDARETLQDALKSAPEYLPAL 298

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 21539655   438 L----ALARLETYENARKVLNKARENIPTDrhiwITAAKLEEAngnTQMVEKIIDRAITSL-RANGVE------------ 500
Cdd:TIGR02917 299 LlagaSEYQLGNLEQAYQYLNQILKYAPNS----HQARRLLAS---IQLRLGRVDEAIATLsPALGLDpddpaalsllge 371

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 21539655   501 --INREQWIQDAEECDRAGSVATCQAVMRAVIGIG--------IEEEDRKHTWMEDADSCVAHNAL----------ECAR 560
Cdd:TIGR02917 372 ayLALGDFEKAAEYLAKATELDPENAAARTQLGISklsqgdpsEAIADLETAAQLDPELGRADLLLilsylrsgqfDKAL 451

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 21539655   561 AIYAYALQVFPSKKSVW--LRAAYFEKNH--GTRESLEALLQRAVAHCPKAEVLWLMGAKskwlAGDVPAARSILALAFQ 636
Cdd:TIGR02917 452 AAAKKLEKKQPDNASLHnlLGAIYLGKGDlaKAREAFEKALSIEPDFFPAAANLARIDIQ----EGNPDDAIQRFEKVLT 527

                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 21539655   637 ANPNSEEIWLAAVKLESENNEYERARRLLAKARSSAPTA---RVFMKSVKLEwvLGNISAAQELCEEALRHYEDFPKLWM 713
Cdd:TIGR02917 528 IDPKNLRAILALAGLYLRTGNEEEAVAWLEKAAELNPQEiepALALAQYYLG--KGQLKKALAILNEAADAAPDSPEAWL 605

                         490       500       510       520       530       540       550       560
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 21539655   714 MKGQIEEQGELMEKAREAYNQGLKKCPHSTPLWLLLSRLEEKIGQLTRARAILEKSRLKNPKNPGLWLESVRLEYRAGLK 793
Cdd:TIGR02917 606 MLGRAQLAAGDLNKAVSSFKKLLALQPDSALALLLLADAYAVMKNYAKAITSLKRALELKPDNTEAQIGLAQLLLAAKRT 685

                         570
                  ....*....|...
gi 21539655   794 NIANTLmAKALQE 806
Cdd:TIGR02917 686 ESAKKI-AKSLQK 697
BepA COG4783
Outer membrane protein chaperone/metalloprotease BepA/YfgC, contains M48 and TPR domains [Cell ...
 672-810 1.06e-11

Outer membrane protein chaperone/metalloprotease BepA/YfgC, contains M48 and TPR domains [Cell wall/membrane/envelope biogenesis, Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 443813 [Multi-domain]  Cd Length: 139  Bit Score: 63.29  E-value: 1.06e-11
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 21539655 672 APTARVFMKSVKLEWVLGNISAAQELCEEALRHYEDFPKLWMMKGQIEEQGELMEKAREAYNQGLKKCPHSTPLWLLLSR 751
Cdd:COG4783   1 AACAEALYALAQALLLAGDYDEAEALLEKALELDPDNPEAFALLGEILLQLGDLDEAIVLLHEALELDPDEPEARLNLGL 80

                        90       100       110       120       130
                ....*....|....*....|....*....|....*....|....*....|....*....
gi 21539655 752 LEEKIGQLTRARAILEKSRLKNPKNPGLWLESVRLEYRAGLKNIANTLMAKALQECPNS 810
Cdd:COG4783  81 ALLKAGDYDEALALLEKALKLDPEHPEAYLRLARAYRALGRPDEAIAALEKALELDPDD 139
LapB COG2956
Lipopolysaccharide biosynthesis regulator YciM/LapB, contains six TPR domains and a C-terminal ...
 712-911 2.67e-11

Lipopolysaccharide biosynthesis regulator YciM/LapB, contains six TPR domains and a C-terminal metal-binding domain [Cell wall/membrane/envelope biogenesis];


Pssm-ID: 442196 [Multi-domain]  Cd Length: 275  Bit Score: 65.14  E-value: 2.67e-11
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 21539655 712 WMMKGQIEEQGELMEKAREAYNQGLKKCPHSTPLWLLLSRLEEKIGQLTRARAILEKSRLKNPKNPGLWLESVRLEYRAG 791
Cdd:COG2956  11 WYFKGLNYLLNGQPDKAIDLLEEALELDPETVEAHLALGNLYRRRGEYDRAIRIHQKLLERDPDRAEALLELAQDYLKAG 90

                        90       100       110       120       130       140       150       160
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 21539655 792 LKNIANTLMAKALQECPNSGILWSEAVFLEARPQRKTKSVDALKKCEH----DPHVLLAVAKLFWSERKITKAREWFHRT 867
Cdd:COG2956  91 LLDRAEELLEKLLELDPDDAEALRLLAEIYEQEGDWEKAIEVLERLLKlgpeNAHAYCELAELYLEQGDYDEAIEALEKA 170

                       170       180       190       200
                ....*....|....*....|....*....|....*....|....
gi 21539655 868 VKIDSDLGDAWAFFYKFELQHGTEEQQEEVRKRCENAEPRHGEL 911
Cdd:COG2956 171 LKLDPDCARALLLLAELYLEQGDYEEAIAALERALEQDPDYLPA 214
LapB COG2956
Lipopolysaccharide biosynthesis regulator YciM/LapB, contains six TPR domains and a C-terminal ...
 289-456 2.85e-11

Lipopolysaccharide biosynthesis regulator YciM/LapB, contains six TPR domains and a C-terminal metal-binding domain [Cell wall/membrane/envelope biogenesis];


Pssm-ID: 442196 [Multi-domain]  Cd Length: 275  Bit Score: 65.14  E-value: 2.85e-11
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 21539655 289 NDIKKARLLLKSVRETNPHHPPAWIASARLEEVTGKLQVARNLIMKGTEMCPKSEDVWLEAAR--LQPGDTAKAVVA--Q 364
Cdd:COG2956  90 GLLDRAEELLEKLLELDPDDAEALRLLAEIYEQEGDWEKAIEVLERLLKLGPENAHAYCELAElyLEQGDYDEAIEAleK 169

                        90       100       110       120       130       140       150       160
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 21539655 365 AVRHLPQSVRIYIRAAELET---DIRAKKRVLRKALEHVPNSV----RLWKAAVELEEPEDARIMLSRAVECCPtSVELW 437
Cdd:COG2956 170 ALKLDPDCARALLLLAELYLeqgDYEEAIAALERALEQDPDYLpalpRLAELYEKLGDPEEALELLRKALELDP-SDDLL 248

                       170       180
                ....*....|....*....|...
gi 21539655 438 LALARL----ETYENARKVLNKA 456
Cdd:COG2956 249 LALADLlerkEGLEAALALLERQ 271
LapB COG2956
Lipopolysaccharide biosynthesis regulator YciM/LapB, contains six TPR domains and a C-terminal ...
 289-516 2.64e-10

Lipopolysaccharide biosynthesis regulator YciM/LapB, contains six TPR domains and a C-terminal metal-binding domain [Cell wall/membrane/envelope biogenesis];


Pssm-ID: 442196 [Multi-domain]  Cd Length: 275  Bit Score: 62.44  E-value: 2.64e-10
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 21539655 289 NDIKKARLLLKSVRETNPHHPPAWIASARLEEVTGKLQVARNLIMKGTEMCPKSEDVWLEAAR--LQPGDTAKAVVA--Q 364
Cdd:COG2956  22 GQPDKAIDLLEEALELDPETVEAHLALGNLYRRRGEYDRAIRIHQKLLERDPDRAEALLELAQdyLKAGLLDRAEELleK 101

                        90       100       110       120       130       140       150       160
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 21539655 365 AVRHLPQSVRIYIRAAEL---ETDIRAKKRVLRKALEHVPNSVRLW----KAAVELEEPEDARIMLSRAVECCPTSVELW 437
Cdd:COG2956 102 LLELDPDDAEALRLLAEIyeqEGDWEKAIEVLERLLKLGPENAHAYcelaELYLEQGDYDEAIEALEKALKLDPDCARAL 181

                       170       180       190       200       210       220       230       240
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 21539655 438 LALARLET----YENARKVLNKARENIPTDRHIWITAAKLEEANGNTQMVEKIIDRAITSLRANGVEINREQWIQDAEEC 513
Cdd:COG2956 182 LLLAELYLeqgdYEEAIAALERALEQDPDYLPALPRLAELYEKLGDPEEALELLRKALELDPSDDLLLALADLLERKEGL 261


                ...
gi 21539655 514 DRA 516
Cdd:COG2956 262 EAA 264
LapB COG2956
Lipopolysaccharide biosynthesis regulator YciM/LapB, contains six TPR domains and a C-terminal ...
 414-705 5.17e-10

Lipopolysaccharide biosynthesis regulator YciM/LapB, contains six TPR domains and a C-terminal metal-binding domain [Cell wall/membrane/envelope biogenesis];


Pssm-ID: 442196 [Multi-domain]  Cd Length: 275  Bit Score: 61.28  E-value: 5.17e-10
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 21539655 414 EEPEDARIMLSRAVECCPTSVELWLALARLET----YENARKVLNKARENIPTDRHIWITAAKLEEANGNTqmvekiiDR 489
Cdd:COG2956  22 GQPDKAIDLLEEALELDPETVEAHLALGNLYRrrgeYDRAIRIHQKLLERDPDRAEALLELAQDYLKAGLL-------DR 94

                        90       100       110       120       130       140       150       160
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 21539655 490 AITSLRaNGVEINREQwiqdaeecdragsvatcQAVMRAVIGIGIEEEDrkhtWmedadscvaHNALECARAiyayALQV 569
Cdd:COG2956  95 AEELLE-KLLELDPDD-----------------AEALRLLAEIYEQEGD----W---------EKAIEVLER----LLKL 139

                       170       180       190       200       210       220       230       240
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 21539655 570 FPSKKSVWLRAAYFEKNHGTRESLEALLQRAVAHCPKAEVLWLMGAKSKWLAGDVPAARSILALAFQANPNSEEIWLAAV 649
Cdd:COG2956 140 GPENAHAYCELAELYLEQGDYDEAIEALEKALKLDPDCARALLLLAELYLEQGDYEEAIAALERALEQDPDYLPALPRLA 219

                       250       260       270       280       290
                ....*....|....*....|....*....|....*....|....*....|....*.
gi 21539655 650 KLESENNEYERARRLLAKARSSAPTARVFMKSVKLEWVLGNISAAQELCEEALRHY 705
Cdd:COG2956 220 ELYEKLGDPEEALELLRKALELDPSDDLLLALADLLERKEGLEAALALLERQLRRH 275
NrfG COG4235
Cytochrome c-type biogenesis protein CcmH/NrfG [Energy production and conversion, ...
 631-754 5.22e-09

Cytochrome c-type biogenesis protein CcmH/NrfG [Energy production and conversion, Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 443378 [Multi-domain]  Cd Length: 131  Bit Score: 55.40  E-value: 5.22e-09
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 21539655 631 LALAFQANPNSEEIWLAAVKLESENNEYERARRLLAKARSSAPT--------ARVFMKSvklewvlGNISAAQELCEEAL 702
Cdd:COG4235   6 LRQALAANPNDAEGWLLLGRAYLRLGRYDEALAAYEKALRLDPDnadalldlAEALLAA-------GDTEEAEELLERAL 78

                        90       100       110       120       130
                ....*....|....*....|....*....|....*....|....*....|..
gi 21539655 703 RHYEDFPKLWMMKGQIEEQGELMEKAREAYNQGLKKCPHSTPLWLLLSRLEE 754
Cdd:COG4235  79 ALDPDNPEALYLLGLAAFQQGDYAEAIAAWQKLLALLPADAPARLLEASIAE 130
PEP_TPR_lipo TIGR02917
putative PEP-CTERM system TPR-repeat lipoprotein; This protein family occurs in strictly ...
 556-813 1.49e-08

putative PEP-CTERM system TPR-repeat lipoprotein; This protein family occurs in strictly within a subset of Gram-negative bacterial species with the proposed PEP-CTERM/exosortase system, analogous to the LPXTG/sortase system common in Gram-positive bacteria. This protein occurs in a species if and only if a transmembrane histidine kinase (TIGR02916) and a DNA-binding response regulator (TIGR02915) also occur. The present of tetratricopeptide repeats (TPR) suggests protein-protein interaction, possibly for the regulation of PEP-CTERM protein expression, since many PEP-CTERM proteins in these genomes are preceded by a proposed DNA binding site for the response regulator.


Pssm-ID: 274350 [Multi-domain]  Cd Length: 899  Bit Score: 58.94  E-value: 1.49e-08
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 21539655   556 LECARAIYAYALQVFPSKKSVWLRAAYFEKNHGTRESLEALLQRAVAHCPKAEVLWLMGAKSKWLAGDVPAARSILALAF 635
Cdd:TIGR02917 141 LELAQKSYEQALAIDPRSLYAKLGLAQLALAENRFDEARALIDEVLTADPGNVDALLLKGDLLLSLGNIELALAAYRKAI 220

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 21539655   636 QANPNSEEIWLAAVKLESENNEYERARR----LLAKARSSaPTARvFMKSVkLEWVLGNISAAQELCEEALRHYEDFPKL 711
Cdd:TIGR02917 221 ALRPNNIAVLLALATILIEAGEFEEAEKhadaLLKKAPNS-PLAH-YLKAL-VDFQKKNYEDARETLQDALKSAPEYLPA 297

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 21539655   712 WMMKGQIEEQGELMEKAREAYNQGLKKCPHSTPLWLLLSRLEEKIGQLTRARAILEKSRLKNPKNPGLwLESVRLEY-RA 790
Cdd:TIGR02917 298 LLLAGASEYQLGNLEQAYQYLNQILKYAPNSHQARRLLASIQLRLGRVDEAIATLSPALGLDPDDPAA-LSLLGEAYlAL 376

                         250       260
                  ....*....|....*....|...
gi 21539655   791 GLKNIANTLMAKALQECPNSGIL 813
Cdd:TIGR02917 377 GDFEKAAEYLAKATELDPENAAA 399
Spy COG3914
Predicted O-linked N-acetylglucosamine transferase, SPINDLY family [Posttranslational ...
 541-780 1.87e-08

Predicted O-linked N-acetylglucosamine transferase, SPINDLY family [Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 443119 [Multi-domain]  Cd Length: 658  Bit Score: 58.08  E-value: 1.87e-08
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 21539655 541 HTWMEDADSCVAHNALECARAIYAYALQVFPSKKSVWLRAAyfeknhgtresLEALLQRAVAHCPKAEVLWLmgakskwl 620
Cdd:COG3914   2 AAAALLALAALAAAALLAAAAAAELALAAELEAAALAAALG-----------LALLLLAALAEAAAAALLAL-------- 62

                        90       100       110       120       130       140       150       160
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 21539655 621 AGDVPAARSILALAFQANPNSEEIWLAavklesENNEYERARRLLAKARSSAPT-ARVFMKSVKLEWVLGNISAAQELCE 699
Cdd:COG3914  63 AAGEAAAAAAALLLLAALLELAALLLQ------ALGRYEEALALYRRALALNPDnAEALFNLGNLLLALGRLEEALAALR 136

                       170       180       190       200       210       220       230       240
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 21539655 700 EALRHYEDFPKLWMMKGQIEEQGELMEKAREAYNQGLKKCPHSTPLWLLLSRLEEKIGQLTRARAILEKSRLKNPKNPGL 779
Cdd:COG3914 137 RALALNPDFAEAYLNLGEALRRLGRLEEAIAALRRALELDPDNAEALNNLGNALQDLGRLEEAIAAYRRALELDPDNADA 216


                .
gi 21539655 780 W 780
Cdd:COG3914 217 H 217
TPR COG0457
Tetratricopeptide (TPR) repeat [General function prediction only];
636-806 1.30e-07

Tetratricopeptide (TPR) repeat [General function prediction only];


Pssm-ID: 440225 [Multi-domain]  Cd Length: 245  Bit Score: 53.86  E-value: 1.30e-07
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 21539655 636 QANPNSEEIWLAAVKLESENNEYERARRLLAKARSSAPT-ARVFMKSVKLEWVLGNISAAQELCEEALRHYEDFPKLWMM 714
Cdd:COG0457   2 ELDPDDAEAYNNLGLAYRRLGRYEEAIEDYEKALELDPDdAEALYNLGLAYLRLGRYEEALADYEQALELDPDDAEALNN 81

                        90       100       110       120       130       140       150       160
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 21539655 715 KGQI-EEQGELmEKAREAYNQGLKKCPHSTPLWLLLSRLEEKIGQLTRARAILEKSRLKNPKNPGLWLESVRLEYRAGLK 793
Cdd:COG0457  82 LGLAlQALGRY-EEALEDYDKALELDPDDAEALYNLGLALLELGRYDEAIEAYERALELDPDDADALYNLGIALEKLGRY 160

                       170
                ....*....|...
gi 21539655 794 NIANTLMAKALQE 806
Cdd:COG0457 161 EEALELLEKLEAA 173
TPR COG0457
Tetratricopeptide (TPR) repeat [General function prediction only];
688-912 2.22e-07

Tetratricopeptide (TPR) repeat [General function prediction only];


Pssm-ID: 440225 [Multi-domain]  Cd Length: 245  Bit Score: 53.09  E-value: 2.22e-07
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 21539655 688 LGNISAAQELCEEALRHYEDFPKLWMMKGQIEEQGELMEKAREAYNQGLKKCPHSTPLWLLLSRLEEKIGQLTRARAILE 767
Cdd:COG0457  21 LGRYEEAIEDYEKALELDPDDAEALYNLGLAYLRLGRYEEALADYEQALELDPDDAEALNNLGLALQALGRYEEALEDYD 100

                        90       100       110       120       130       140       150       160
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 21539655 768 KSRLKNPKNPGLWLESVRLEYRAGLKNIANTLMAKALQECPNSGILWSEAVFLEARPQRKTKSVDALKKCEHDPHVLLAV 847
Cdd:COG0457 101 KALELDPDDAEALYNLGLALLELGRYDEAIEAYERALELDPDDADALYNLGIALEKLGRYEEALELLEKLEAAALAALLA 180

                       170       180       190       200       210       220
                ....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 21539655 848 AKLFWSERkitKAREWFHRTVKIDSDLGDAWAFFYKFELQHGTEEQQEEVRKRCENAEPRHGELW 912
Cdd:COG0457 181 AALGEAAL---ALAAAEVLLALLLALEQALRKKLAILTLAALAELLLLALALLLALRLAALALYQ 242
BepA COG4783
Outer membrane protein chaperone/metalloprotease BepA/YfgC, contains M48 and TPR domains [Cell ...
 378-491 5.04e-07

Outer membrane protein chaperone/metalloprotease BepA/YfgC, contains M48 and TPR domains [Cell wall/membrane/envelope biogenesis, Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 443813 [Multi-domain]  Cd Length: 139  Bit Score: 49.81  E-value: 5.04e-07
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 21539655 378 RAAELETDIRAKKRVLRKALEHVPNSVRLW----KAAVELEEPEDARIMLSRAVECCPTSVELWLALA----RLETYENA 449
Cdd:COG4783  12 QALLLAGDYDEAEALLEKALELDPDNPEAFallgEILLQLGDLDEAIVLLHEALELDPDEPEARLNLGlallKAGDYDEA 91

                        90       100       110       120
                ....*....|....*....|....*....|....*....|..
gi 21539655 450 RKVLNKARENIPTDRHIWITAAKLEEANGNTQMVEKIIDRAI 491
Cdd:COG4783  92 LALLEKALKLDPEHPEAYLRLARAYRALGRPDEAIAALEKAL 133
BepA COG4783
Outer membrane protein chaperone/metalloprotease BepA/YfgC, contains M48 and TPR domains [Cell ...
 543-673 8.32e-07

Outer membrane protein chaperone/metalloprotease BepA/YfgC, contains M48 and TPR domains [Cell wall/membrane/envelope biogenesis, Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 443813 [Multi-domain]  Cd Length: 139  Bit Score: 49.42  E-value: 8.32e-07
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 21539655 543 WMEDADSCVAHNALECARAIYAYALQVFPSKKSVWLRAAYFEKNHGTRESLEALLQRAVAHCPKAEVLWLMGAKSKWLAG 622
Cdd:COG4783   7 LYALAQALLLAGDYDEAEALLEKALELDPDNPEAFALLGEILLQLGDLDEAIVLLHEALELDPDEPEARLNLGLALLKAG 86

                        90       100       110       120       130
                ....*....|....*....|....*....|....*....|....*....|.
gi 21539655 623 DVPAARSILALAFQANPNSEEIWLAAVKLESENNEYERARRLLAKARSSAP 673
Cdd:COG4783  87 DYDEALALLEKALKLDPEHPEAYLRLARAYRALGRPDEAIAALEKALELDP 137
BepA COG4783
Outer membrane protein chaperone/metalloprotease BepA/YfgC, contains M48 and TPR domains [Cell ...
 712-836 1.02e-06

Outer membrane protein chaperone/metalloprotease BepA/YfgC, contains M48 and TPR domains [Cell wall/membrane/envelope biogenesis, Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 443813 [Multi-domain]  Cd Length: 139  Bit Score: 49.03  E-value: 1.02e-06
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 21539655 712 WMMKGQIEEQGELMEKAREAYNQGLKKCPHSTPLWLLLSRLEEKIGQLTRARAILEKSRLKNPKNPGLWLESVRLEYRAG 791
Cdd:COG4783   7 LYALAQALLLAGDYDEAEALLEKALELDPDNPEAFALLGEILLQLGDLDEAIVLLHEALELDPDEPEARLNLGLALLKAG 86

                        90       100       110       120
                ....*....|....*....|....*....|....*....|....*
gi 21539655 792 LKNIANTLMAKALQECPNSGILWSEAVFLEARPQRKTKSVDALKK 836
Cdd:COG4783  87 DYDEALALLEKALKLDPEHPEAYLRLARAYRALGRPDEAIAALEK 131
LapB COG2956
Lipopolysaccharide biosynthesis regulator YciM/LapB, contains six TPR domains and a C-terminal ...
 392-668 1.35e-06

Lipopolysaccharide biosynthesis regulator YciM/LapB, contains six TPR domains and a C-terminal metal-binding domain [Cell wall/membrane/envelope biogenesis];


Pssm-ID: 442196 [Multi-domain]  Cd Length: 275  Bit Score: 50.88  E-value: 1.35e-06
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 21539655 392 VLRKALEHVPNSVRLWKAAVEL----EEPEDARIMLSRAVECCPTSVELWLALARLET----YENARKVLNKARENIPTD 463
Cdd:COG2956  30 LLEEALELDPETVEAHLALGNLyrrrGEYDRAIRIHQKLLERDPDRAEALLELAQDYLkaglLDRAEELLEKLLELDPDD 109

                        90       100       110       120       130       140       150       160
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 21539655 464 RHIWITAAKLEEANGNTQMVEKIIDRAITslrangveinreqwiqdaeecdragsvatcqavmravigigiEEEDRKHTW 543
Cdd:COG2956 110 AEALRLLAEIYEQEGDWEKAIEVLERLLK------------------------------------------LGPENAHAY 147

                       170       180       190       200       210       220       230       240
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 21539655 544 MEDADSCVAHNALECARAIYAYALQVFPSKKSVWLRAAYFEKNHGTRESLEALLQRAVAHCPKAEVLWLMGAKSKWLAGD 623
Cdd:COG2956 148 CELAELYLEQGDYDEAIEALEKALKLDPDCARALLLLAELYLEQGDYEEAIAALERALEQDPDYLPALPRLAELYEKLGD 227

                       250       260       270       280
                ....*....|....*....|....*....|....*....|....*
gi 21539655 624 VPAARSILALAFQANPNSEEiWLAAVKLESENNEYERARRLLAKA 668
Cdd:COG2956 228 PEEALELLRKALELDPSDDL-LLALADLLERKEGLEAALALLERQ 271
TadD COG5010
Flp pilus assembly protein TadD, contains TPR repeats [Intracellular trafficking, secretion, ...
 626-774 3.38e-06

Flp pilus assembly protein TadD, contains TPR repeats [Intracellular trafficking, secretion, and vesicular transport, Extracellular structures];


Pssm-ID: 444034 [Multi-domain]  Cd Length: 155  Bit Score: 48.03  E-value: 3.38e-06
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 21539655 626 AARSILALAFQANPNSEEIWLAAVKLESENNEYERARRLLAKARSSAPTARVFMKSVKLEwvLGNISAAQELCEEALRHY 705
Cdd:COG5010   7 FDRLPLYLLLLTKLRTLVEKYEAALAGANNTKEDELAAAGRDKLAKAFAIESPSDNLYNK--LGDFEESLALLEQALQLD 84

                        90       100       110       120       130       140
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 21539655 706 EDFPKLWMMKGQIEEQGELMEKAREAYNQGLKKCPHSTPLWLLLSRLEEKIGQLTRARAILEKSRLKNP 774
Cdd:COG5010  85 PNNPELYYNLALLYSRSGDKDEAKEYYEKALALSPDNPNAYSNLAALLLSLGQDDEAKAALQRALGTSP 153
BepA COG4783
Outer membrane protein chaperone/metalloprotease BepA/YfgC, contains M48 and TPR domains [Cell ...
 575-708 4.92e-06

Outer membrane protein chaperone/metalloprotease BepA/YfgC, contains M48 and TPR domains [Cell wall/membrane/envelope biogenesis, Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 443813 [Multi-domain]  Cd Length: 139  Bit Score: 47.11  E-value: 4.92e-06
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 21539655 575 SVWLRAAYFEKNHGTRESLEALLQRAVAHCPKAEVLWLMGAKSKWLAGDVPAARSILALAFQANPNSEEIWLAAVKLESE 654
Cdd:COG4783   5 EALYALAQALLLAGDYDEAEALLEKALELDPDNPEAFALLGEILLQLGDLDEAIVLLHEALELDPDEPEARLNLGLALLK 84

                        90       100       110       120       130
                ....*....|....*....|....*....|....*....|....*....|....*
gi 21539655 655 NNEYERARRLLAKARSSAPT-ARVFMKSVKLEWVLGNISAAQELCEEALRHYEDF 708
Cdd:COG4783  85 AGDYDEALALLEKALKLDPEhPEAYLRLARAYRALGRPDEAIAALEKALELDPDD 139
TPR COG0457
Tetratricopeptide (TPR) repeat [General function prediction only];
594-796 7.78e-06

Tetratricopeptide (TPR) repeat [General function prediction only];


Pssm-ID: 440225 [Multi-domain]  Cd Length: 245  Bit Score: 48.46  E-value: 7.78e-06
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 21539655 594 EALLQRAVAHCPKAEVLWLMGAKSKWLAGDVPAARSILALAFQANPNSEEIWLAAVKLESENNEYERARRLLAKA---RS 670
Cdd:COG0457  28 IEDYEKALELDPDDAEALYNLGLAYLRLGRYEEALADYEQALELDPDDAEALNNLGLALQALGRYEEALEDYDKAlelDP 107

                        90       100       110       120       130       140       150       160
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 21539655 671 SAPTARVFMKSVKLEwvLGNISAAQELCEEALRHYEDFPKLWMMKGQIEEQGELMEKAREAYNQGLKKCPHSTPLWLLLS 750
Cdd:COG0457 108 DDAEALYNLGLALLE--LGRYDEAIEAYERALELDPDDADALYNLGIALEKLGRYEEALELLEKLEAAALAALLAAALGE 185

                       170       180       190       200
                ....*....|....*....|....*....|....*....|....*.
gi 21539655 751 RLEEKIGQLTRARAILEKSRLKNPKNPGLWLESVRLEYRAGLKNIA 796
Cdd:COG0457 186 AALALAAAEVLLALLLALEQALRKKLAILTLAALAELLLLALALLL 231
NrfG COG4235
Cytochrome c-type biogenesis protein CcmH/NrfG [Energy production and conversion, ...
 693-823 8.65e-06

Cytochrome c-type biogenesis protein CcmH/NrfG [Energy production and conversion, Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 443378 [Multi-domain]  Cd Length: 131  Bit Score: 46.15  E-value: 8.65e-06
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 21539655 693 AAQELCEEALRHYEDFPKLWMMKGQIEEQGELMEKAREAYNQGLKKCPHSTPLWLLLSRLEEKIGQLTRARAILEKSRLK 772
Cdd:COG4235   1 EAIARLRQALAANPNDAEGWLLLGRAYLRLGRYDEALAAYEKALRLDPDNADALLDLAEALLAAGDTEEAEELLERALAL 80

                        90       100       110       120       130
                ....*....|....*....|....*....|....*....|....*....|.
gi 21539655 773 NPKNPGLWLESVRLEYRAGLKNIANTLMAKALQECPNSgilwSEAVFLEAR 823
Cdd:COG4235  81 DPDNPEALYLLGLAAFQQGDYAEAIAAWQKLLALLPAD----APARLLEAS 127
HemYx COG3071
Uncharacterized protein HemY, contains HemY_N domain and TPR repeats (unrelated to ...
 581-879 1.19e-05

Uncharacterized protein HemY, contains HemY_N domain and TPR repeats (unrelated to protoporphyrinogen oxidase HemY) [Function unknown];


Pssm-ID: 442305 [Multi-domain]  Cd Length: 323  Bit Score: 48.37  E-value: 1.19e-05
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 21539655 581 AYFEKNHGTREsleALLQRAVAHCPKAEVLWLMGAKSKWLAGDVPAARSILALAFQANPNSEE-IWLAAVKLESENNEYE 659
Cdd:COG3071  26 ALAEGRYARAE---KLLSKAAEHSEAPLLAYLLAARAAQALGDYERRDEYLAQALELAPEAELaVLLTRAELLLDQGQAE 102

                        90       100       110       120       130       140       150       160
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 21539655 660 RARRLLAKARSSAP-TARVFMKSVKLEWVLGNISAAQELCEEALRHyedfpklwmmkGQIEEQgELMEKAREAYNQGLKK 738
Cdd:COG3071 103 QALATLEALRAGAPrHPQVLRLLLQAYRQLGDWEELLELLPALRKH-----------KALSAE-EAQALERRAYLGLLRQ 170

                       170       180       190       200       210       220       230       240
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 21539655 739 CPHSTP----LWLLLSRLEEKigqltraraileksrlknpkNPGLWLESVRLEYRAGLKNIANTLMAKALQECPNSGILw 814
Cdd:COG3071 171 AARDAEalkaLWKALPRAERR--------------------DPELAAAYARALIALGDHDEAERLLREALKRQWDPRLV- 229

                       250       260       270       280       290       300
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 21539655 815 seAVFLEARPQRKTKSV----DALKKCEHDPHVLLAVAKLFWSERKITKAREWFHRTVKIDSDlGDAWA 879
Cdd:COG3071 230 --RLYGRLQGGDPAKQLkraeKWLKKHPNDPDLLLALGRLCLRNQLWGKAREYLEAALALRPS-AEAYA 295
COG5191 COG5191
Uncharacterized conserved protein, contains HAT (Half-A-TPR) repeat [General function ...
 696-787 2.79e-05

Uncharacterized conserved protein, contains HAT (Half-A-TPR) repeat [General function prediction only];


Pssm-ID: 227518 [Multi-domain]  Cd Length: 435  Bit Score: 47.65  E-value: 2.79e-05
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 21539655 696 ELCEEALRHYEDfPKLWMMKGQIEEQGELMEKAREAYNQGLKKCPHSTPLWLLLSRLE-EKIGQLTRARAILEKSRLKNP 774
Cdd:COG5191  95 ELYRSTNKFFND-PKIWSQYAAYVIKKKMYGEMKNIFAECLTKHPLNVDLWIYCCAFElFEIANIESSRAMFLKGLRMNS 173

                        90
                ....*....|...
gi 21539655 775 KNPGLWLESVRLE 787
Cdd:COG5191 174 RSPRIWIEYFRME 186
TadD COG5010
Flp pilus assembly protein TadD, contains TPR repeats [Intracellular trafficking, secretion, ...
 661-808 3.38e-05

Flp pilus assembly protein TadD, contains TPR repeats [Intracellular trafficking, secretion, and vesicular transport, Extracellular structures];


Pssm-ID: 444034 [Multi-domain]  Cd Length: 155  Bit Score: 44.95  E-value: 3.38e-05
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 21539655 661 ARRLLAKARSSAPTARVFMKSVKLEWVLGNISAAQELCEEALRHYEDFPKLWMMKGQIEEqgelmekAREAYNQGLKKCP 740
Cdd:COG5010  13 YLLLLTKLRTLVEKYEAALAGANNTKEDELAAAGRDKLAKAFAIESPSDNLYNKLGDFEE-------SLALLEQALQLDP 85

                        90       100       110       120       130       140
                ....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 21539655 741 HSTPLWLLLSRLEEKIGQLTRARAILEKSRLKNPKNPGLWLESVRLEYRAGLKNIANTLMAKALQECP 808
Cdd:COG5010  86 NNPELYYNLALLYSRSGDKDEAKEYYEKALALSPDNPNAYSNLAALLLSLGQDDEAKAALQRALGTSP 153
PEP_TPR_lipo TIGR02917
putative PEP-CTERM system TPR-repeat lipoprotein; This protein family occurs in strictly ...
 615-873 6.92e-05

putative PEP-CTERM system TPR-repeat lipoprotein; This protein family occurs in strictly within a subset of Gram-negative bacterial species with the proposed PEP-CTERM/exosortase system, analogous to the LPXTG/sortase system common in Gram-positive bacteria. This protein occurs in a species if and only if a transmembrane histidine kinase (TIGR02916) and a DNA-binding response regulator (TIGR02915) also occur. The present of tetratricopeptide repeats (TPR) suggests protein-protein interaction, possibly for the regulation of PEP-CTERM protein expression, since many PEP-CTERM proteins in these genomes are preceded by a proposed DNA binding site for the response regulator.


Pssm-ID: 274350 [Multi-domain]  Cd Length: 899  Bit Score: 47.00  E-value: 6.92e-05
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 21539655   615 AKSKWLAGDVPAARSILALAFQANPNSEE-------IWLAAVKLESENNEYERARRL-LAKARSSAPTARVFMKSVKLEW 686
Cdd:TIGR02917  29 AKSYLQKNKYKAAIIQLKNALQKDPNDAEarfllgkIYLALGDYAAAEKELRKALSLgYPKNQVLPLLARAYLLQGKFQQ 108

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 21539655   687 VLgnisaaQELCEEALRHYEDFPKLWMMKGQIEEQGELMEKAREAYNQGLKKCPHSTPLWLLLSRLEEKIGQLTRARAIL 766
Cdd:TIGR02917 109 VL------DELPGKTLLDDEGAAELLALRGLAYLGLGQLELAQKSYEQALAIDPRSLYAKLGLAQLALAENRFDEARALI 182

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 21539655   767 EKSRLKNPKNPGLWLESVRLEYRAGLKNIANTLMAKALQECPN--------SGILWSEAVFLEARPQRKTksvdALKKCE 838
Cdd:TIGR02917 183 DEVLTADPGNVDALLLKGDLLLSLGNIELALAAYRKAIALRPNniavllalATILIEAGEFEEAEKHADA----LLKKAP 258

                         250       260       270
                  ....*....|....*....|....*....|....*
gi 21539655   839 HDPHVLLAVAKLFWSERKITKAREWFHRTVKIDSD 873
Cdd:TIGR02917 259 NSPLAHYLKALVDFQKKNYEDARETLQDALKSAPE 293
PilF COG3063
Type IV pilus assembly protein PilF/PilW [Cell motility, Extracellular structures];
688-775 7.05e-05

Type IV pilus assembly protein PilF/PilW [Cell motility, Extracellular structures];


Pssm-ID: 442297 [Multi-domain]  Cd Length: 94  Bit Score: 42.46  E-value: 7.05e-05
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 21539655 688 LGNISAAQELCEEALRHYEDFPKLWMMKGQI-EEQGELmEKArEAYNQGLKKCPHSTPLWLLLSRLEEKIGQLTRARAIL 766
Cdd:COG3063   5 LGDLEEAEEYYEKALELDPDNADALNNLGLLlLEQGRY-DEA-IALEKALKLDPNNAEALLNLAELLLELGDYDEALAYL 82


                ....*....
gi 21539655 767 EKSRLKNPK 775
Cdd:COG3063  83 ERALELDPS 91
NrfG COG4235
Cytochrome c-type biogenesis protein CcmH/NrfG [Energy production and conversion, ...
 393-510 1.12e-04

Cytochrome c-type biogenesis protein CcmH/NrfG [Energy production and conversion, Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 443378 [Multi-domain]  Cd Length: 131  Bit Score: 43.07  E-value: 1.12e-04
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 21539655 393 LRKALEHVPNSVRLW----KAAVELEEPEDARIMLSRAVECCPTSVELWLALARLETYEN----ARKVLNKARENIPTDR 464
Cdd:COG4235   6 LRQALAANPNDAEGWlllgRAYLRLGRYDEALAAYEKALRLDPDNADALLDLAEALLAAGdteeAEELLERALALDPDNP 85

                        90       100       110       120
                ....*....|....*....|....*....|....*....|....*.
gi 21539655 465 HIWITAAKLEEANGNTQMVEKIIDRAITSLRANGVEINREQWIQDA 510
Cdd:COG4235  86 EALYLLGLAAFQQGDYAEAIAAWQKLLALLPADAPARLLEASIAEA 131
TadD COG5010
Flp pilus assembly protein TadD, contains TPR repeats [Intracellular trafficking, secretion, ...
 378-491 2.14e-04

Flp pilus assembly protein TadD, contains TPR repeats [Intracellular trafficking, secretion, and vesicular transport, Extracellular structures];


Pssm-ID: 444034 [Multi-domain]  Cd Length: 155  Bit Score: 42.64  E-value: 2.14e-04
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 21539655 378 RAAELETDIRAKKRVLRKALEHVPNSVRLWKAAVELEEPEDARIMLSRAVECCPTSVELWLALA----RLETYENARKVL 453
Cdd:COG5010  32 AGANNTKEDELAAAGRDKLAKAFAIESPSDNLYNKLGDFEESLALLEQALQLDPNNPELYYNLAllysRSGDKDEAKEYY 111

                        90       100       110
                ....*....|....*....|....*....|....*...
gi 21539655 454 NKARENIPTDRHIWITAAKLEEANGNTQMVEKIIDRAI 491
Cdd:COG5010 112 EKALALSPDNPNAYSNLAALLLSLGQDDEAKAALQRAL 149
PRK11788 PRK11788
tetratricopeptide repeat protein; Provisional
 352-494 2.38e-04

tetratricopeptide repeat protein; Provisional


Pssm-ID: 236983 [Multi-domain]  Cd Length: 389  Bit Score: 44.41  E-value: 2.38e-04
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 21539655  352 LQPGDTAKAV--VAQAVRHLPQSVR-------IYIRAAELETDIRAKKRVLRKALEHVPNSV-RLWKAAVELEEPEDARI 421
Cdd:PRK11788 191 LARGDLDAARalLKKALAADPQCVRasillgdLALAQGDYAAAIEALERVEEQDPEYLSEVLpKLMECYQALGDEAEGLE 270

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 21539655  422 MLSRAVECCPtSVELWLALAR-LETYENARKVLNKARENI---PTDR--HIWITAAKLEEANGNT----QMVEKIIDRAI 491
Cdd:PRK11788 271 FLRRALEEYP-GADLLLALAQlLEEQEGPEAAQALLREQLrrhPSLRgfHRLLDYHLAEAEEGRAkeslLLLRDLVGEQL 349


                 ...
gi 21539655  492 TSL 494
Cdd:PRK11788 350 KRK 352
ACL4-like cd24142
Assembly chaperone of ribosomal protein L4 and similar proteins; Assembly chaperone of RPL4 ...
 393-524 2.43e-04

Assembly chaperone of ribosomal protein L4 and similar proteins; Assembly chaperone of RPL4 (ACL4) acts as a chaperone for the L4 ribosomal subunit, encoded by RPL4A and RPL4B, and is required for hierarchical ribosome assembly. It is required for the soluble expression of newly synthesized RPL4 and for the protection of RPL4 from the Tom1-dependent cellular degradation machinery. ACL4 shields ribosomal protein L4 until timely release and insertion into the pre-ribosome is possible, once ribosomal protein L18 is present.


Pssm-ID: 467942 [Multi-domain]  Cd Length: 306  Bit Score: 44.16  E-value: 2.43e-04
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 21539655 393 LRKALEHVPNSVRLWKAA----VELEEPEDARIMLSRAVECCPT-SVELWLALARLETYENARKVLNKARENIptDRHIW 467
Cdd:cd24142  23 LQRALELEPNNVEALELLgeilLELGDVEEAREVLLRAIELDPDgGYEKYLYLGQLSGGEEALQYYEKGIEIL--EEELQ 100

                        90       100       110       120       130
                ....*....|....*....|....*....|....*....|....*....|....*..
gi 21539655 468 ITAAKLEEANGNTQMVEKIIDRAITSLrangveinREQWIQDAeeCDRAGSVATCQA 524
Cdd:cd24142 101 ALQAASAEAEEEAEELKRKLSSALCAL--------AEIYMTDL--CDEPDAEQRCEE 147
PEP_TPR_lipo TIGR02917
putative PEP-CTERM system TPR-repeat lipoprotein; This protein family occurs in strictly ...
 289-487 4.93e-04

putative PEP-CTERM system TPR-repeat lipoprotein; This protein family occurs in strictly within a subset of Gram-negative bacterial species with the proposed PEP-CTERM/exosortase system, analogous to the LPXTG/sortase system common in Gram-positive bacteria. This protein occurs in a species if and only if a transmembrane histidine kinase (TIGR02916) and a DNA-binding response regulator (TIGR02915) also occur. The present of tetratricopeptide repeats (TPR) suggests protein-protein interaction, possibly for the regulation of PEP-CTERM protein expression, since many PEP-CTERM proteins in these genomes are preceded by a proposed DNA binding site for the response regulator.


Pssm-ID: 274350 [Multi-domain]  Cd Length: 899  Bit Score: 43.92  E-value: 4.93e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 21539655   289 NDIKKARLLLKSVRETNPHHPPAWIASARLEEVTGKLQVARNLIMKGTEMCPKSEDVWLEAARLQ--PGDTAKAV--VAQ 364
Cdd:TIGR02917 479 GDLAKAREAFEKALSIEPDFFPAAANLARIDIQEGNPDDAIQRFEKVLTIDPKNLRAILALAGLYlrTGNEEEAVawLEK 558

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 21539655   365 AVRHLPQSVRIYIRAAE-LETDIRAKK--RVLRKALEHVPNSVRLW----KAAVELEEPEDARIMLSRAVECCPTSVELW 437
Cdd:TIGR02917 559 AAELNPQEIEPALALAQyYLGKGQLKKalAILNEAADAAPDSPEAWlmlgRAQLAAGDLNKAVSSFKKLLALQPDSALAL 638

                         170       180       190       200       210
                  ....*....|....*....|....*....|....*....|....*....|....
gi 21539655   438 LALA----RLETYENARKVLNKARENIPTDRHIWITAAKLEEANGNTQMVEKII 487
Cdd:TIGR02917 639 LLLAdayaVMKNYAKAITSLKRALELKPDNTEAQIGLAQLLLAAKRTESAKKIA 692
TPR_19 pfam14559
Tetratricopeptide repeat;
621-673 5.06e-04

Tetratricopeptide repeat;


Pssm-ID: 434038 [Multi-domain]  Cd Length: 65  Bit Score: 39.10  E-value: 5.06e-04
                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|...
gi 21539655   621 AGDVPAARSILALAFQANPNSEEIWLAAVKLESENNEYERARRLLAKARSSAP 673
Cdd:pfam14559   1 EGDYAEALELLEQALAEDPDNAEARLGLAEALLALGRLDEAEALLAALPAADP 53
TadD COG5010
Flp pilus assembly protein TadD, contains TPR repeats [Intracellular trafficking, secretion, ...
 559-675 5.89e-04

Flp pilus assembly protein TadD, contains TPR repeats [Intracellular trafficking, secretion, and vesicular transport, Extracellular structures];


Pssm-ID: 444034 [Multi-domain]  Cd Length: 155  Bit Score: 41.48  E-value: 5.89e-04
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 21539655 559 ARAIYAYALQVFPSKKSVWLRAAYFEKNHgtRESLEALLQRAVAHCPKAEVLWLMGAKSKWLAGDVPAARSILALAFQAN 638
Cdd:COG5010  41 ELAAAGRDKLAKAFAIESPSDNLYNKLGD--FEESLALLEQALQLDPNNPELYYNLALLYSRSGDKDEAKEYYEKALALS 118

                        90       100       110
                ....*....|....*....|....*....|....*..
gi 21539655 639 PNSEEIWLAAVKLESENNEYERARRLLAKARSSAPTA 675
Cdd:COG5010 119 PDNPNAYSNLAALLLSLGQDDEAKAALQRALGTSPLK 155
PEP_TPR_lipo TIGR02917
putative PEP-CTERM system TPR-repeat lipoprotein; This protein family occurs in strictly ...
 622-877 6.25e-04

putative PEP-CTERM system TPR-repeat lipoprotein; This protein family occurs in strictly within a subset of Gram-negative bacterial species with the proposed PEP-CTERM/exosortase system, analogous to the LPXTG/sortase system common in Gram-positive bacteria. This protein occurs in a species if and only if a transmembrane histidine kinase (TIGR02916) and a DNA-binding response regulator (TIGR02915) also occur. The present of tetratricopeptide repeats (TPR) suggests protein-protein interaction, possibly for the regulation of PEP-CTERM protein expression, since many PEP-CTERM proteins in these genomes are preceded by a proposed DNA binding site for the response regulator.


Pssm-ID: 274350 [Multi-domain]  Cd Length: 899  Bit Score: 43.53  E-value: 6.25e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 21539655   622 GDVPAARSILALAFQANPNSEEIWLAAVKLESENNEYERARRLLAKARSSAPTAR-VFMKSVKLEWVLGNISAAQELCEE 700
Cdd:TIGR02917 139 GQLELAQKSYEQALAIDPRSLYAKLGLAQLALAENRFDEARALIDEVLTADPGNVdALLLKGDLLLSLGNIELALAAYRK 218

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 21539655   701 ALRHYEDFPKLWMMKGQIEEQGELMEKAREAYNQGLKKCPHSTPLWLLLSRLEEKIGQLTRARAILEKSRLKNPKNPGLW 780
Cdd:TIGR02917 219 AIALRPNNIAVLLALATILIEAGEFEEAEKHADALLKKAPNSPLAHYLKALVDFQKKNYEDARETLQDALKSAPEYLPAL 298

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 21539655   781 LESVRLEYRAGLKNIANTLMAKALQECPNSgilwSEAVFLEARPQRKTKSVD--------ALKKCEHDPHVLLAVAKLFW 852
Cdd:TIGR02917 299 LLAGASEYQLGNLEQAYQYLNQILKYAPNS----HQARRLLASIQLRLGRVDeaiatlspALGLDPDDPAALSLLGEAYL 374

                         250       260
                  ....*....|....*....|....*
gi 21539655   853 SERKITKAREWFHRTVKIDSDLGDA 877
Cdd:TIGR02917 375 ALGDFEKAAEYLAKATELDPENAAA 399
PEP_TPR_lipo TIGR02917
putative PEP-CTERM system TPR-repeat lipoprotein; This protein family occurs in strictly ...
 323-777 6.98e-04

putative PEP-CTERM system TPR-repeat lipoprotein; This protein family occurs in strictly within a subset of Gram-negative bacterial species with the proposed PEP-CTERM/exosortase system, analogous to the LPXTG/sortase system common in Gram-positive bacteria. This protein occurs in a species if and only if a transmembrane histidine kinase (TIGR02916) and a DNA-binding response regulator (TIGR02915) also occur. The present of tetratricopeptide repeats (TPR) suggests protein-protein interaction, possibly for the regulation of PEP-CTERM protein expression, since many PEP-CTERM proteins in these genomes are preceded by a proposed DNA binding site for the response regulator.


Pssm-ID: 274350 [Multi-domain]  Cd Length: 899  Bit Score: 43.53  E-value: 6.98e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 21539655   323 GKLQVARNLIMKGTEMCPKSEDVWLEAA--RLQPGDTAKAVVA--QAVRHLPQSVRI-------YIRAAELETDIRAKKR 391
Cdd:TIGR02917 377 GDFEKAAEYLAKATELDPENAAARTQLGisKLSQGDPSEAIADleTAAQLDPELGRAdlllilsYLRSGQFDKALAAAKK 456

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 21539655   392 VLRKAlehvPNSVRLW--KAAVEL--EEPEDARIMLSRAVECCPTSVELWLALARLETYEN----ARKVLNKARENIPTD 463
Cdd:TIGR02917 457 LEKKQ----PDNASLHnlLGAIYLgkGDLAKAREAFEKALSIEPDFFPAAANLARIDIQEGnpddAIQRFEKVLTIDPKN 532

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 21539655   464 RHIWITAAKLEEANGNTQMVEKIIDRAItslRANGVEInrEQWIQDAEECDRAGSVATCQAVMRAVIGIgieEEDRKHTW 543
Cdd:TIGR02917 533 LRAILALAGLYLRTGNEEEAVAWLEKAA---ELNPQEI--EPALALAQYYLGKGQLKKALAILNEAADA---APDSPEAW 604

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 21539655   544 MEDADSCVAHNALECARAIYAYALQVFPSKKSVWLRAAYFEKNHGTRESLEALLQRAVAHCPKAEVLWLMGAKSKWLAGD 623
Cdd:TIGR02917 605 LMLGRAQLAAGDLNKAVSSFKKLLALQPDSALALLLLADAYAVMKNYAKAITSLKRALELKPDNTEAQIGLAQLLLAAKR 684

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 21539655   624 VPAARSILALAFQANPNSEEIWLAAVKLESENNEYERARRLLAKARSSAPTARVFMKSVKLEWVLGNISAAQELCEEALR 703
Cdd:TIGR02917 685 TESAKKIAKSLQKQHPKAALGFELEGDLYLRQKDYPAAIQAYRKALKRAPSSQNAIKLHRALLASGNTAEAVKTLEAWLK 764

                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 21539655   704 -HYEDFPKLWMMKGQIEEQGELmEKAREAYNQGLKKCPHSTPL-----WLLLsrleekigQLTRARAIL--EKSRLKNPK 775
Cdd:TIGR02917 765 tHPNDAVLRTALAELYLAQKDY-DKAIKHYQTVVKKAPDNAVVlnnlaWLYL--------ELKDPRALEyaERALKLAPN 835


                  ..
gi 21539655   776 NP 777
Cdd:TIGR02917 836 IP 837
HemYx COG3898
Uncharacterized protein HemY, contains HemY_N domain and TPR repeats (unrelated to HemY-type ...
 347-520 7.52e-04

Uncharacterized protein HemY, contains HemY_N domain and TPR repeats (unrelated to HemY-type protoporphyrinogen oxidase) [Function unknown];


Pssm-ID: 443105 [Multi-domain]  Cd Length: 468  Bit Score: 42.96  E-value: 7.52e-04
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 21539655 347 LEAARLQPGDTAKAVVAqavrhlpqsVRIYIRAAELetdiRAKKRVLRKALEHVPNSvRLWKAAVELEEPEDARIMLSRA 426
Cdd:COG3898 251 IEALKLAPDLVPAAVLA---------ARLLIAQGKL----RKAAKVLEKAWRAQPHP-DLAAAYAELRPGDSALDRLKRA 316

                        90       100       110       120       130       140       150       160
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 21539655 427 ---VECCPTSVELWLALARL----ETYENARKVLNKARENIPTDRhIWITAAKLEEA-NGNTQMVEKIIDRAITSLRAng 498
Cdd:COG3898 317 etlAALNPDHPESRLALAEAalaaGDFGEARRALGPLLEERPTAR-VCLLMAEIERGeHGDDGRVREWLARALRAPRD-- 393

                       170       180
                ....*....|....*....|..
gi 21539655 499 veinrEQWIqdaeeCDRAGSVA 520
Cdd:COG3898 394 -----PAWV-----CDACGTVS 405
TPR COG0457
Tetratricopeptide (TPR) repeat [General function prediction only];
393-516 1.30e-03

Tetratricopeptide (TPR) repeat [General function prediction only];


Pssm-ID: 440225 [Multi-domain]  Cd Length: 245  Bit Score: 41.53  E-value: 1.30e-03
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 21539655 393 LRKALEHVPNSVRLW----KAAVELEEPEDARIMLSRAVECCPTSVELW----LALARLETYENARKVLNKARENIPTDR 464
Cdd:COG0457  65 YEQALELDPDDAEALnnlgLALQALGRYEEALEDYDKALELDPDDAEALynlgLALLELGRYDEAIEAYERALELDPDDA 144

                        90       100       110       120       130
                ....*....|....*....|....*....|....*....|....*....|..
gi 21539655 465 HIWITAAKLEEANGNTQMVEKIIDRAITSLRANGVEINREQWIQDAEECDRA 516
Cdd:COG0457 145 DALYNLGIALEKLGRYEEALELLEKLEAAALAALLAAALGEAALALAAAEVL 196
HAT smart00386
HAT (Half-A-TPR) repeats; Present in several RNA-binding proteins. Structurally and ...
 444-476 1.61e-03

HAT (Half-A-TPR) repeats; Present in several RNA-binding proteins. Structurally and sequentially thought to be similar to TPRs.


Pssm-ID: 214642 [Multi-domain]  Cd Length: 33  Bit Score: 36.76  E-value: 1.61e-03
                           10        20        30
                   ....*....|....*....|....*....|...
gi 21539655    444 ETYENARKVLNKARENIPTDRHIWITAAKLEEA 476
Cdd:smart00386   1 GDIERARKIYERALEKFPKSVELWLKYAEFEER 33
HemYx COG3071
Uncharacterized protein HemY, contains HemY_N domain and TPR repeats (unrelated to ...
 289-481 1.70e-03

Uncharacterized protein HemY, contains HemY_N domain and TPR repeats (unrelated to protoporphyrinogen oxidase HemY) [Function unknown];


Pssm-ID: 442305 [Multi-domain]  Cd Length: 323  Bit Score: 41.43  E-value: 1.70e-03
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 21539655 289 NDIKKARLLLKSVRETNPHHPPAWIASARLEEVTGKLQVARNL--------IMKGTEMCPKSEDVWLEAARLQPGDTA-- 358
Cdd:COG3071  99 GQAEQALATLEALRAGAPRHPQVLRLLLQAYRQLGDWEELLELlpalrkhkALSAEEAQALERRAYLGLLRQAARDAEal 178

                        90       100       110       120       130       140       150       160
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 21539655 359 KAVVAQ---AVRHLPQSVRIYIRAAELETDIRAKKRVLRKALEHVPNS--VRLWkAAVELEEPEDARIMLSRAVECCPTS 433
Cdd:COG3071 179 KALWKAlprAERRDPELAAAYARALIALGDHDEAERLLREALKRQWDPrlVRLY-GRLQGGDPAKQLKRAEKWLKKHPND 257

                       170       180       190       200       210
                ....*....|....*....|....*....|....*....|....*....|..
gi 21539655 434 VELWLALARLETYEN----ARKVLNKARENIPtDRHIWITAAKLEEANGNTQ 481
Cdd:COG3071 258 PDLLLALGRLCLRNQlwgkAREYLEAALALRP-SAEAYAELARLLEQLGDPE 308
HAT smart00386
HAT (Half-A-TPR) repeats; Present in several RNA-binding proteins. Structurally and ...
 725-755 1.83e-03

HAT (Half-A-TPR) repeats; Present in several RNA-binding proteins. Structurally and sequentially thought to be similar to TPRs.


Pssm-ID: 214642 [Multi-domain]  Cd Length: 33  Bit Score: 36.76  E-value: 1.83e-03
                           10        20        30
                   ....*....|....*....|....*....|.
gi 21539655    725 MEKAREAYNQGLKKCPHSTPLWLLLSRLEEK 755
Cdd:smart00386   3 IERARKIYERALEKFPKSVELWLKYAEFEER 33
HemYx COG3898
Uncharacterized protein HemY, contains HemY_N domain and TPR repeats (unrelated to HemY-type ...
 599-774 2.09e-03

Uncharacterized protein HemY, contains HemY_N domain and TPR repeats (unrelated to HemY-type protoporphyrinogen oxidase) [Function unknown];


Pssm-ID: 443105 [Multi-domain]  Cd Length: 468  Bit Score: 41.80  E-value: 2.09e-03
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 21539655 599 RAVAHCPKAEVLWLMG-AKSKWLAGDVPAARSILALAFQANPNSEEIWLAAVKLESENNEYERARRLLAKARSSAPTARV 677
Cdd:COG3898 142 EAMLEDPETRFLGLRGlMVEALRRGDTEAALALAEEALALAPKLPWAQDALLELQAAAGDWDGALATLDAALKAGLLDKD 221

                        90       100       110       120       130       140       150       160
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 21539655 678 FMKSVKLewVLgnisaaqeLCEEALRHyedfpklwmmkgqieEQGElMEKAREAYNQGLKKCPHSTPLWLLLSRLEEKIG 757
Cdd:COG3898 222 VARRRRA--VL--------LTARAREL---------------EEGD-PDEARELAIEALKLAPDLVPAAVLAARLLIAQG 275

                       170
                ....*....|....*..
gi 21539655 758 QLTRARAILEKSRLKNP 774
Cdd:COG3898 276 KLRKAAKVLEKAWRAQP 292
BepA COG4783
Outer membrane protein chaperone/metalloprotease BepA/YfgC, contains M48 and TPR domains [Cell ...
 288-403 2.26e-03

Outer membrane protein chaperone/metalloprotease BepA/YfgC, contains M48 and TPR domains [Cell wall/membrane/envelope biogenesis, Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 443813 [Multi-domain]  Cd Length: 139  Bit Score: 39.40  E-value: 2.26e-03
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 21539655 288 INDIKKARLLLKSVRETNPHHPPAWIASARLEEVTGKLQVARNLIMKGTEMCPKSEDVWLEAA----RLQPGDTAKAVVA 363
Cdd:COG4783  17 AGDYDEAEALLEKALELDPDNPEAFALLGEILLQLGDLDEAIVLLHEALELDPDEPEARLNLGlallKAGDYDEALALLE 96

                        90       100       110       120
                ....*....|....*....|....*....|....*....|...
gi 21539655 364 QAVRHLPQSVRIYIRAAELETDIRAKKR---VLRKALEHVPNS 403
Cdd:COG4783  97 KALKLDPEHPEAYLRLARAYRALGRPDEaiaALEKALELDPDD 139
NrfG COG4235
Cytochrome c-type biogenesis protein CcmH/NrfG [Energy production and conversion, ...
 688-777 3.45e-03

Cytochrome c-type biogenesis protein CcmH/NrfG [Energy production and conversion, Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 443378 [Multi-domain]  Cd Length: 131  Bit Score: 38.45  E-value: 3.45e-03
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 21539655 688 LGNISAAQELCEEALRHYEDFPKLWMMKGQIEEQGELMEKAREAYNQGLKKCPHSTPLWLLLSRLEEKIGQLTRARAILE 767
Cdd:COG4235  30 LGRYDEALAAYEKALRLDPDNADALLDLAEALLAAGDTEEAEELLERALALDPDNPEALYLLGLAAFQQGDYAEAIAAWQ 109

                        90
                ....*....|
gi 21539655 768 KSRLKNPKNP 777
Cdd:COG4235 110 KLLALLPADA 119
TPR COG0457
Tetratricopeptide (TPR) repeat [General function prediction only];
707-908 5.15e-03

Tetratricopeptide (TPR) repeat [General function prediction only];


Pssm-ID: 440225 [Multi-domain]  Cd Length: 245  Bit Score: 39.60  E-value: 5.15e-03
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 21539655 707 DFPKLWMMKGQIEEQGELMEKAREAYNQGLKKCPHSTPLWLLLSRLEEKIGQLTRARAILEKSRLKNPKNPGLWLesvrl 786
Cdd:COG0457   6 DDAEAYNNLGLAYRRLGRYEEAIEDYEKALELDPDDAEALYNLGLAYLRLGRYEEALADYEQALELDPDDAEALN----- 80

                        90       100       110       120       130       140       150       160
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 21539655 787 eyraglkNIANTLMAKALQEcpnsgilwsEAVFLEARpqrktksvdALKKCEHDPHVLLAVAKLFWSERKITKAREWFHR 866
Cdd:COG0457  81 -------NLGLALQALGRYE---------EALEDYDK---------ALELDPDDAEALYNLGLALLELGRYDEAIEAYER 135

                       170       180       190       200
                ....*....|....*....|....*....|....*....|..
gi 21539655 867 TVKIDSDLGDAWAFFYKFELQHGTEEQQEEVRKRCENAEPRH 908
Cdd:COG0457 136 ALELDPDDADALYNLGIALEKLGRYEEALELLEKLEAAALAA 177
NrfG COG4235
Cytochrome c-type biogenesis protein CcmH/NrfG [Energy production and conversion, ...
 727-837 5.25e-03

Cytochrome c-type biogenesis protein CcmH/NrfG [Energy production and conversion, Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 443378 [Multi-domain]  Cd Length: 131  Bit Score: 38.06  E-value: 5.25e-03
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 21539655 727 KAREAYNQGLKKCPHSTPLWLLLSRLEEKIGQLTRARAILEKSRLKNPKNPGLWLESVRLEYRAGLKNIANTLMAKALQE 806
Cdd:COG4235   1 EAIARLRQALAANPNDAEGWLLLGRAYLRLGRYDEALAAYEKALRLDPDNADALLDLAEALLAAGDTEEAEELLERALAL 80

                        90       100       110
                ....*....|....*....|....*....|.
gi 21539655 807 CPNSGILWSEAVFLEARPQRKTKSVDALKKC 837
Cdd:COG4235  81 DPDNPEALYLLGLAAFQQGDYAEAIAAWQKL 111
Spy COG3914
Predicted O-linked N-acetylglucosamine transferase, SPINDLY family [Posttranslational ...
 343-467 5.57e-03

Predicted O-linked N-acetylglucosamine transferase, SPINDLY family [Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 443119 [Multi-domain]  Cd Length: 658  Bit Score: 40.36  E-value: 5.57e-03
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 21539655 343 EDVWLEAARLQPGDTAKAVVAQAVRHLPQSVRIYIRAAELETDIRAKK---RVLRKALEHVPNSVRLW----KAAVELEE 415
Cdd:COG3914  82 ELAALLLQALGRYEEALALYRRALALNPDNAEALFNLGNLLLALGRLEealAALRRALALNPDFAEAYlnlgEALRRLGR 161

                        90       100       110       120       130
                ....*....|....*....|....*....|....*....|....*....|....*.
gi 21539655 416 PEDARIMLSRAVECCPTSVELWLALAR----LETYENARKVLNKARENIPTDRHIW 467
Cdd:COG3914 162 LEEAIAALRRALELDPDNAEALNNLGNalqdLGRLEEAIAAYRRALELDPDNADAH 217
TadD COG5010
Flp pilus assembly protein TadD, contains TPR repeats [Intracellular trafficking, secretion, ...
 346-461 6.99e-03

Flp pilus assembly protein TadD, contains TPR repeats [Intracellular trafficking, secretion, and vesicular transport, Extracellular structures];


Pssm-ID: 444034 [Multi-domain]  Cd Length: 155  Bit Score: 38.40  E-value: 6.99e-03
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 21539655 346 WLEAARLQPGDTAKAVVAQAVRHLPQSVRIYIRAAELETDIRAKKRVLRKALEHVPNSVRLW----KAAVELEEPEDARI 421
Cdd:COG5010  30 ALAGANNTKEDELAAAGRDKLAKAFAIESPSDNLYNKLGDFEESLALLEQALQLDPNNPELYynlaLLYSRSGDKDEAKE 109

                        90       100       110       120
                ....*....|....*....|....*....|....*....|....
gi 21539655 422 MLSRAVECCPTSVELW----LALARLETYENARKVLNKARENIP 461
Cdd:COG5010 110 YYEKALALSPDNPNAYsnlaALLLSLGQDDEAKAALQRALGTSP 153
TadD COG5010
Flp pilus assembly protein TadD, contains TPR repeats [Intracellular trafficking, secretion, ...
 555-703 7.26e-03

Flp pilus assembly protein TadD, contains TPR repeats [Intracellular trafficking, secretion, and vesicular transport, Extracellular structures];


Pssm-ID: 444034 [Multi-domain]  Cd Length: 155  Bit Score: 38.40  E-value: 7.26e-03
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 21539655 555 ALECARAIYAYALQVFPSKKSVWLRAAYFEKNHGTRESLEALLQRAVAHCPKAEVLWLMGAKSKWLAGDVPAARSILALA 634
Cdd:COG5010   1 ARALEGFDRLPLYLLLLTKLRTLVEKYEAALAGANNTKEDELAAAGRDKLAKAFAIESPSDNLYNKLGDFEESLALLEQA 80

                        90       100       110       120       130       140       150
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 21539655 635 FQANPNSEEIWLAAVKLESENNEYERARRLLAKARSSAPT-ARVFMKSVKLEWVLGNISAAQELCEEALR 703
Cdd:COG5010  81 LQLDPNNPELYYNLALLYSRSGDKDEAKEYYEKALALSPDnPNAYSNLAALLLSLGQDDEAKAALQRALG 150
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
Help | Disclaimer | Write to the Help Desk
NCBI | NLM | NIH