|
Name |
Accession |
Description |
Interval |
E-value |
| PlsC |
COG0204 |
1-acyl-sn-glycerol-3-phosphate acyltransferase [Lipid transport and metabolism]; ... |
47-261 |
6.04e-52 |
|
1-acyl-sn-glycerol-3-phosphate acyltransferase [Lipid transport and metabolism]; 1-acyl-sn-glycerol-3-phosphate acyltransferase is part of the Pathway/BioSystem: Phospholipid biosynthesis
Pssm-ID: 439974 [Multi-domain] Cd Length: 215 Bit Score: 168.65 E-value: 6.04e-52
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24582854 47 FMILRPRDYRnalFPSWCFRQLCRLVGITMEVRGLENVRKDHGAVVIMNHQSAVDLCVLAYLWPVigRATVVSKKEVLYI 126
Cdd:COG0204 5 FLLLRRFRYR---LVRLWARLLLRLLGVRVRVEGLENLPADGPVLIVANHQSWLDILLLLAALPR--PVRFVAKKELFKI 79
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24582854 127 PFFGIGAWLWGTLYIDRSRKTDSINSLQKEAKAIQERNCkLLLFPEGTRNSKDSLLPFKKGSFHIALQGKSPVQPVVISK 206
Cdd:COG0204 80 PLLGWLLRALGAIPVDRSKRRAALRALRQAVEALKAGES-LVIFPEGTRSPDGRLLPFKTGAARLALEAGVPIVPVAIDG 158
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|....*
gi 24582854 207 YSFMDDEKKTFRPGHALIHILPEVSTEKYKREDVQLLIDECQSIMQTEYTKLSKE 261
Cdd:COG0204 159 TERALPKGFLPRPGKVTVRIGPPIDPSDLEGEDRRELAERLRAAIEALLAELRAE 213
|
|
| LPLAT_AGPAT-like |
cd07989 |
Lysophospholipid Acyltransferases (LPLATs) of Glycerophospholipid Biosynthesis: AGPAT-like; ... |
65-248 |
2.10e-45 |
|
Lysophospholipid Acyltransferases (LPLATs) of Glycerophospholipid Biosynthesis: AGPAT-like; Lysophospholipid acyltransferase (LPLAT) superfamily member: acyltransferases of de novo and remodeling pathways of glycerophospholipid biosynthesis which catalyze the incorporation of an acyl group from either acylCoAs or acyl-acyl carrier proteins (acylACPs) into acceptors such as glycerol 3-phosphate, dihydroxyacetone phosphate or lyso-phosphatidic acid. Included in this subgroup are such LPLATs as 1-acyl-sn-glycerol-3-phosphate acyltransferase (AGPAT, PlsC), Tafazzin (product of Barth syndrome gene), and similar proteins.
Pssm-ID: 153251 [Multi-domain] Cd Length: 184 Bit Score: 150.88 E-value: 2.10e-45
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24582854 65 FRQLCRLVGITMEVRGLENVRKDHGAVVIMNHQSAVDLCVLAYLWPviGRATVVSKKEVLYIPFFGIGAWLWGTLYIDRS 144
Cdd:cd07989 1 LRLLLRLLGVRVRVEGLENLPPKGPVIIVANHQSYLDPLVLGAALP--RPIRFVAKKELFKIPFLGWLLRLLGAIPIDRG 78
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24582854 145 RKTDSINSLQKEAKAIQErNCKLLLFPEGTRNSKDSLLPFKKGSFHIALQGKSPVQPVVIS-KYSFMDDEKKTFRPGHAL 223
Cdd:cd07989 79 NGRSAREALREAIEALKE-GESVVIFPEGTRSRDGELLPFKSGAFRLAKEAGVPIVPVAISgTWGSLPKGKKLPRPGRVT 157
|
170 180
....*....|....*....|....*..
gi 24582854 224 IHILPEVSTEKYK--REDVQLLIDECQ 248
Cdd:cd07989 158 VRIGEPIPPEGLElaEEDRKELREKVR 184
|
|
| Acyltransferase |
pfam01553 |
Acyltransferase; This family contains acyltransferases involved in phospholipid biosynthesis ... |
77-205 |
1.80e-38 |
|
Acyltransferase; This family contains acyltransferases involved in phospholipid biosynthesis and other proteins of unknown function. This family also includes tafazzin, the Barth syndrome gene.
Pssm-ID: 366704 [Multi-domain] Cd Length: 131 Bit Score: 131.25 E-value: 1.80e-38
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24582854 77 EVRGLENVRKDHGAVVIMNHQSAVDLCVLAYLWPVIGRATV-VSKKEVLYIPFFGIGAWLWGTLYIDRSRKTDSINSLQK 155
Cdd:pfam01553 3 EVHGLENLPRGGPAIVVANHQSYLDVLLLSLALYKRGRPLVfVAKKELFDIPLVGWLMRLLGCIFIDRKNRKDAAGTLEY 82
|
90 100 110 120 130
....*....|....*....|....*....|....*....|....*....|
gi 24582854 156 EAKAIqERNCKLLLFPEGTRNSKDSLLPFKKGSFHIALQGKSPVQPVVIS 205
Cdd:pfam01553 83 LVELL-REGKLVVIFPEGTRSREGELLPFKKGAFRLAIEAGVPIVPVAIS 131
|
|
| AGP_acyltrn |
TIGR00530 |
1-acyl-sn-glycerol-3-phosphate acyltransferases; This model describes the core homologous ... |
73-205 |
7.54e-37 |
|
1-acyl-sn-glycerol-3-phosphate acyltransferases; This model describes the core homologous region of a collection of related proteins, several of which are known to act as 1-acyl-sn-glycerol-3-phosphate acyltransferases (EC 2.3.1.51). Proteins scoring above the trusted cutoff are likely to have the same general activity. However, there is variation among characterized members as to whether the acyl group can be donated by acyl carrier protein or coenzyme A, and in the length and saturation of the donated acyl group. 1-acyl-sn-glycerol-3-phosphate acyltransferase is also called 1-AGP acyltransferase, lysophosphatidic acid acyltransferase, and LPA acyltransferase. [Fatty acid and phospholipid metabolism, Biosynthesis]
Pssm-ID: 129621 [Multi-domain] Cd Length: 130 Bit Score: 127.08 E-value: 7.54e-37
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24582854 73 GITMEVRGLENVRKDHGAVVIMNHQSAVDLCVLAYLWPVigRATVVSKKEVLYIPFFGIGAWLWGTLYIDRsRKTDSINS 152
Cdd:TIGR00530 1 GLKVEVVGPENLPAKSPVLVVANHQSNLDPLTLSAAFPP--PIVFIAKKELKWIPFFGIMLWLTGAIFIDR-ENIRAIAT 77
|
90 100 110 120 130
....*....|....*....|....*....|....*....|....*....|...
gi 24582854 153 LQKEAKAIQERNCKLLLFPEGTRNSKDSLLPFKKGSFHIALQGKSPVQPVVIS 205
Cdd:TIGR00530 78 ALKAAIEVLKQGRSIGVFPEGTRSRGRDILPFKKGAFHIAIKAGVPILPVVLS 130
|
|
| PlsC |
smart00563 |
Phosphate acyltransferases; Function in phospholipid biosynthesis and have either ... |
90-205 |
1.26e-36 |
|
Phosphate acyltransferases; Function in phospholipid biosynthesis and have either glycerolphosphate, 1-acylglycerolphosphate, or 2-acylglycerolphosphoethanolamine acyltransferase activities. Tafazzin, the product of the gene mutated in patients with Barth syndrome, is a member of this family.
Pssm-ID: 214724 [Multi-domain] Cd Length: 118 Bit Score: 126.32 E-value: 1.26e-36
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24582854 90 AVVIMNHQSAVDLCVLAYLWPVIG-RATVVSKKEVLYIPFFGIGAWLWGTLYIDRSRKTDSINSLQKEAKAIQErNCKLL 168
Cdd:smart00563 1 ALVVANHQSFLDPLVLSALLPRKLgRVRFVAKKELFYVPLLGWLLRLLGAIFIDRSNGRKARAALREAVELLKE-GEWLL 79
|
90 100 110
....*....|....*....|....*....|....*..
gi 24582854 169 LFPEGTRNSKDSLLPFKKGSFHIALQGKSPVQPVVIS 205
Cdd:smart00563 80 IFPEGTRSRPGKLLPFKKGAARLALEAGVPIVPVAIR 116
|
|
| PRK15018 |
PRK15018 |
1-acyl-sn-glycerol-3-phosphate acyltransferase; Provisional |
26-261 |
9.18e-29 |
|
1-acyl-sn-glycerol-3-phosphate acyltransferase; Provisional
Pssm-ID: 184979 Cd Length: 245 Bit Score: 109.72 E-value: 9.18e-29
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24582854 26 YQMRMFFIFFGAGLIVFLCVPFMILRPRDYRNALFPSWCFRQLCRLVGITMEVRGLENVRKDHGAVVIMNHQSAVDLCVL 105
Cdd:PRK15018 3 YIFRLIITVIYSILVCVFGSIYCLFSPRNPKHVATFGHMFGRLAPLFGLKVECRKPADAESYGNAIYIANHQNNYDMVTA 82
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24582854 106 AYLwpVIGRATVVSKKEVLYIPFFGIGAWLWGTLYIDRSRKTDSINSLQKEAKAIQERNCKLLLFPEGTRNSKDSLLPFK 185
Cdd:PRK15018 83 SNI--VQPPTVTVGKKSLLWIPFFGQLYWLTGNLLIDRNNRTKAHGTIAEVVNHFKKRRISIWMFPEGTRSRGRGLLPFK 160
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 24582854 186 KGSFHIALQGKSPVQPVVISKYSFMDDEKKtFRPGHALIHILPEVSTEKYKREDVQLLIDECQSIMQTEYTKLSKE 261
Cdd:PRK15018 161 TGAFHAAIAAGVPIIPVCVSTTSNKINLNR-LHNGLVIVEMLPPIDVSQYGKDQVRELAAHCRSIMEQKIAELDKE 235
|
|
| |
|
Name |
Accession |
Description |
Interval |
E-value |
| PlsC |
COG0204 |
1-acyl-sn-glycerol-3-phosphate acyltransferase [Lipid transport and metabolism]; ... |
47-261 |
6.04e-52 |
|
1-acyl-sn-glycerol-3-phosphate acyltransferase [Lipid transport and metabolism]; 1-acyl-sn-glycerol-3-phosphate acyltransferase is part of the Pathway/BioSystem: Phospholipid biosynthesis
Pssm-ID: 439974 [Multi-domain] Cd Length: 215 Bit Score: 168.65 E-value: 6.04e-52
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24582854 47 FMILRPRDYRnalFPSWCFRQLCRLVGITMEVRGLENVRKDHGAVVIMNHQSAVDLCVLAYLWPVigRATVVSKKEVLYI 126
Cdd:COG0204 5 FLLLRRFRYR---LVRLWARLLLRLLGVRVRVEGLENLPADGPVLIVANHQSWLDILLLLAALPR--PVRFVAKKELFKI 79
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24582854 127 PFFGIGAWLWGTLYIDRSRKTDSINSLQKEAKAIQERNCkLLLFPEGTRNSKDSLLPFKKGSFHIALQGKSPVQPVVISK 206
Cdd:COG0204 80 PLLGWLLRALGAIPVDRSKRRAALRALRQAVEALKAGES-LVIFPEGTRSPDGRLLPFKTGAARLALEAGVPIVPVAIDG 158
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|....*
gi 24582854 207 YSFMDDEKKTFRPGHALIHILPEVSTEKYKREDVQLLIDECQSIMQTEYTKLSKE 261
Cdd:COG0204 159 TERALPKGFLPRPGKVTVRIGPPIDPSDLEGEDRRELAERLRAAIEALLAELRAE 213
|
|
| LPLAT_AGPAT-like |
cd07989 |
Lysophospholipid Acyltransferases (LPLATs) of Glycerophospholipid Biosynthesis: AGPAT-like; ... |
65-248 |
2.10e-45 |
|
Lysophospholipid Acyltransferases (LPLATs) of Glycerophospholipid Biosynthesis: AGPAT-like; Lysophospholipid acyltransferase (LPLAT) superfamily member: acyltransferases of de novo and remodeling pathways of glycerophospholipid biosynthesis which catalyze the incorporation of an acyl group from either acylCoAs or acyl-acyl carrier proteins (acylACPs) into acceptors such as glycerol 3-phosphate, dihydroxyacetone phosphate or lyso-phosphatidic acid. Included in this subgroup are such LPLATs as 1-acyl-sn-glycerol-3-phosphate acyltransferase (AGPAT, PlsC), Tafazzin (product of Barth syndrome gene), and similar proteins.
Pssm-ID: 153251 [Multi-domain] Cd Length: 184 Bit Score: 150.88 E-value: 2.10e-45
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24582854 65 FRQLCRLVGITMEVRGLENVRKDHGAVVIMNHQSAVDLCVLAYLWPviGRATVVSKKEVLYIPFFGIGAWLWGTLYIDRS 144
Cdd:cd07989 1 LRLLLRLLGVRVRVEGLENLPPKGPVIIVANHQSYLDPLVLGAALP--RPIRFVAKKELFKIPFLGWLLRLLGAIPIDRG 78
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24582854 145 RKTDSINSLQKEAKAIQErNCKLLLFPEGTRNSKDSLLPFKKGSFHIALQGKSPVQPVVIS-KYSFMDDEKKTFRPGHAL 223
Cdd:cd07989 79 NGRSAREALREAIEALKE-GESVVIFPEGTRSRDGELLPFKSGAFRLAKEAGVPIVPVAISgTWGSLPKGKKLPRPGRVT 157
|
170 180
....*....|....*....|....*..
gi 24582854 224 IHILPEVSTEKYK--REDVQLLIDECQ 248
Cdd:cd07989 158 VRIGEPIPPEGLElaEEDRKELREKVR 184
|
|
| Acyltransferase |
pfam01553 |
Acyltransferase; This family contains acyltransferases involved in phospholipid biosynthesis ... |
77-205 |
1.80e-38 |
|
Acyltransferase; This family contains acyltransferases involved in phospholipid biosynthesis and other proteins of unknown function. This family also includes tafazzin, the Barth syndrome gene.
Pssm-ID: 366704 [Multi-domain] Cd Length: 131 Bit Score: 131.25 E-value: 1.80e-38
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24582854 77 EVRGLENVRKDHGAVVIMNHQSAVDLCVLAYLWPVIGRATV-VSKKEVLYIPFFGIGAWLWGTLYIDRSRKTDSINSLQK 155
Cdd:pfam01553 3 EVHGLENLPRGGPAIVVANHQSYLDVLLLSLALYKRGRPLVfVAKKELFDIPLVGWLMRLLGCIFIDRKNRKDAAGTLEY 82
|
90 100 110 120 130
....*....|....*....|....*....|....*....|....*....|
gi 24582854 156 EAKAIqERNCKLLLFPEGTRNSKDSLLPFKKGSFHIALQGKSPVQPVVIS 205
Cdd:pfam01553 83 LVELL-REGKLVVIFPEGTRSREGELLPFKKGAFRLAIEAGVPIVPVAIS 131
|
|
| AGP_acyltrn |
TIGR00530 |
1-acyl-sn-glycerol-3-phosphate acyltransferases; This model describes the core homologous ... |
73-205 |
7.54e-37 |
|
1-acyl-sn-glycerol-3-phosphate acyltransferases; This model describes the core homologous region of a collection of related proteins, several of which are known to act as 1-acyl-sn-glycerol-3-phosphate acyltransferases (EC 2.3.1.51). Proteins scoring above the trusted cutoff are likely to have the same general activity. However, there is variation among characterized members as to whether the acyl group can be donated by acyl carrier protein or coenzyme A, and in the length and saturation of the donated acyl group. 1-acyl-sn-glycerol-3-phosphate acyltransferase is also called 1-AGP acyltransferase, lysophosphatidic acid acyltransferase, and LPA acyltransferase. [Fatty acid and phospholipid metabolism, Biosynthesis]
Pssm-ID: 129621 [Multi-domain] Cd Length: 130 Bit Score: 127.08 E-value: 7.54e-37
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24582854 73 GITMEVRGLENVRKDHGAVVIMNHQSAVDLCVLAYLWPVigRATVVSKKEVLYIPFFGIGAWLWGTLYIDRsRKTDSINS 152
Cdd:TIGR00530 1 GLKVEVVGPENLPAKSPVLVVANHQSNLDPLTLSAAFPP--PIVFIAKKELKWIPFFGIMLWLTGAIFIDR-ENIRAIAT 77
|
90 100 110 120 130
....*....|....*....|....*....|....*....|....*....|...
gi 24582854 153 LQKEAKAIQERNCKLLLFPEGTRNSKDSLLPFKKGSFHIALQGKSPVQPVVIS 205
Cdd:TIGR00530 78 ALKAAIEVLKQGRSIGVFPEGTRSRGRDILPFKKGAFHIAIKAGVPILPVVLS 130
|
|
| PlsC |
smart00563 |
Phosphate acyltransferases; Function in phospholipid biosynthesis and have either ... |
90-205 |
1.26e-36 |
|
Phosphate acyltransferases; Function in phospholipid biosynthesis and have either glycerolphosphate, 1-acylglycerolphosphate, or 2-acylglycerolphosphoethanolamine acyltransferase activities. Tafazzin, the product of the gene mutated in patients with Barth syndrome, is a member of this family.
Pssm-ID: 214724 [Multi-domain] Cd Length: 118 Bit Score: 126.32 E-value: 1.26e-36
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24582854 90 AVVIMNHQSAVDLCVLAYLWPVIG-RATVVSKKEVLYIPFFGIGAWLWGTLYIDRSRKTDSINSLQKEAKAIQErNCKLL 168
Cdd:smart00563 1 ALVVANHQSFLDPLVLSALLPRKLgRVRFVAKKELFYVPLLGWLLRLLGAIFIDRSNGRKARAALREAVELLKE-GEWLL 79
|
90 100 110
....*....|....*....|....*....|....*..
gi 24582854 169 LFPEGTRNSKDSLLPFKKGSFHIALQGKSPVQPVVIS 205
Cdd:smart00563 80 IFPEGTRSRPGKLLPFKKGAARLALEAGVPIVPVAIR 116
|
|
| PRK15018 |
PRK15018 |
1-acyl-sn-glycerol-3-phosphate acyltransferase; Provisional |
26-261 |
9.18e-29 |
|
1-acyl-sn-glycerol-3-phosphate acyltransferase; Provisional
Pssm-ID: 184979 Cd Length: 245 Bit Score: 109.72 E-value: 9.18e-29
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24582854 26 YQMRMFFIFFGAGLIVFLCVPFMILRPRDYRNALFPSWCFRQLCRLVGITMEVRGLENVRKDHGAVVIMNHQSAVDLCVL 105
Cdd:PRK15018 3 YIFRLIITVIYSILVCVFGSIYCLFSPRNPKHVATFGHMFGRLAPLFGLKVECRKPADAESYGNAIYIANHQNNYDMVTA 82
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24582854 106 AYLwpVIGRATVVSKKEVLYIPFFGIGAWLWGTLYIDRSRKTDSINSLQKEAKAIQERNCKLLLFPEGTRNSKDSLLPFK 185
Cdd:PRK15018 83 SNI--VQPPTVTVGKKSLLWIPFFGQLYWLTGNLLIDRNNRTKAHGTIAEVVNHFKKRRISIWMFPEGTRSRGRGLLPFK 160
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 24582854 186 KGSFHIALQGKSPVQPVVISKYSFMDDEKKtFRPGHALIHILPEVSTEKYKREDVQLLIDECQSIMQTEYTKLSKE 261
Cdd:PRK15018 161 TGAFHAAIAAGVPIIPVCVSTTSNKINLNR-LHNGLVIVEMLPPIDVSQYGKDQVRELAAHCRSIMEQKIAELDKE 235
|
|
| LPLAT_LPCAT1-like |
cd07991 |
Lysophospholipid Acyltransferases (LPLATs) of Glycerophospholipid Biosynthesis: LPCAT1-like; ... |
65-251 |
6.44e-21 |
|
Lysophospholipid Acyltransferases (LPLATs) of Glycerophospholipid Biosynthesis: LPCAT1-like; Lysophospholipid acyltransferase (LPLAT) superfamily member: acyltransferases of de novo and remodeling pathways of glycerophospholipid biosynthesis which catalyze the incorporation of an acyl group from either acylCoAs or acyl-acyl carrier proteins (acylACPs) into acceptors such as glycerol 3-phosphate, dihydroxyacetone phosphate or lyso-phosphatidic acid. Included in this subgroup are such LPLATs as lysophosphatidylcholine acyltransferase 1 (LPCAT-1), glycerol-3-phosphate acyltransferase 3 (GPAT3), and similar sequences.
Pssm-ID: 153253 [Multi-domain] Cd Length: 211 Bit Score: 87.66 E-value: 6.44e-21
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24582854 65 FRQLCRLVGI-TMEVRGLENvRKDHGAVVIMNHQSAVDLCVLAYLWPvigrATVVSKKEVLYIPFFGIGAWLWGTLYIDR 143
Cdd:cd07991 1 ARVLLFAFGFyVIKVHGKPD-PPEAPRIIVANHTSFIDPLILFSDLF----PSIVAKKELGKLPFIGTILRALGCIFVDR 75
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24582854 144 SrktdSINSLQKEAKAIQERNCK-----LLLFPEGTRNSKDSLLPFKKGSFHIALqgksPVQPVVIsKYS--FMDDEKKT 216
Cdd:cd07991 76 S----EPKDRKKVVEEIKERATDpnwppILIFPEGTTTNGKALIMFKKGAFEPGV----PVQPVAI-RYPnkFVDAFWNS 146
|
170 180 190 200
....*....|....*....|....*....|....*....|....*....
gi 24582854 217 FRPG--------------HALIHILPeVSTEKYKREDVQLLIDECQSIM 251
Cdd:cd07991 147 SGYSslmylfrlltqpanVLEVEFLP-VYTPSEEGEDPKEFANRVRLIM 194
|
|
| LPLAT |
cd06551 |
Lysophospholipid acyltransferases (LPLATs) of glycerophospholipid biosynthesis; ... |
65-233 |
7.04e-18 |
|
Lysophospholipid acyltransferases (LPLATs) of glycerophospholipid biosynthesis; Lysophospholipid acyltransferase (LPLAT) superfamily members are acyltransferases of de novo and remodeling pathways of glycerophospholipid biosynthesis. These proteins catalyze the incorporation of an acyl group from either acylCoAs or acyl-acyl carrier proteins (acylACPs) into acceptors such as glycerol 3-phosphate, dihydroxyacetone phosphate or lyso-phosphatidic acid. Included in this superfamily are LPLATs such as glycerol-3-phosphate 1-acyltransferase (GPAT, PlsB), 1-acyl-sn-glycerol-3-phosphate acyltransferase (AGPAT, PlsC), lysophosphatidylcholine acyltransferase 1 (LPCAT-1), lysophosphatidylethanolamine acyltransferase (LPEAT, also known as, MBOAT2, membrane-bound O-acyltransferase domain-containing protein 2), lipid A biosynthesis lauroyl/myristoyl acyltransferase, 2-acylglycerol O-acyltransferase (MGAT), dihydroxyacetone phosphate acyltransferase (DHAPAT, also known as 1 glycerol-3-phosphate O-acyltransferase 1) and Tafazzin (the protein product of the Barth syndrome (TAZ) gene).
Pssm-ID: 153244 [Multi-domain] Cd Length: 187 Bit Score: 79.00 E-value: 7.04e-18
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24582854 65 FRQLCRL--VGITMEVRGLENVRKDHGAVVIMNHQSAVDLCVLAYL------WPVIGratVVSKKEVLYIPFFGIGawlw 136
Cdd:cd06551 1 FRYLLLNffGFVRLEVKGPPPPPGGGPVLFVSNHSSWWDGLILFLLlerglrRDVYG---LMDEELLERYPFFTRL---- 73
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24582854 137 GTLYIDRSRKTDSINSLQKEAKAIQERNCKLLLFPEGTRNSKDS-LLPFKKGSFHIALQGKSPVQPVVISkYSFMDDEKK 215
Cdd:cd06551 74 GAFSVDRDSPRSAAKSLKYVARLLSKPGSVVWIFPEGTRTRRDKrPLQFKPGVAHLAEKAGVPIVPVALR-YTFELFEQF 152
|
170
....*....|....*...
gi 24582854 216 tfrpGHALIHILPEVSTE 233
Cdd:cd06551 153 ----PEIFVRIGPPIPYA 166
|
|
| LPLAT_LCLAT1-like |
cd07990 |
Lysophospholipid Acyltransferases (LPLATs) of Glycerophospholipid Biosynthesis: LCLAT1-like; ... |
73-178 |
9.37e-17 |
|
Lysophospholipid Acyltransferases (LPLATs) of Glycerophospholipid Biosynthesis: LCLAT1-like; Lysophospholipid acyltransferase (LPLAT) superfamily member: acyltransferases of de novo and remodeling pathways of glycerophospholipid biosynthesis which catalyze the incorporation of an acyl group from either acylCoAs or acyl-acyl carrier proteins (acylACPs) into acceptors such as glycerol 3-phosphate, dihydroxyacetone phosphate or lyso-phosphatidic acid. Included in this subgroup are such LPLATs as Lysocardiolipin acyltransferase 1 (LCLAT1) or 1-acyl-sn-glycerol-3-phosphate acyltransferase and similar proteins.
Pssm-ID: 153252 [Multi-domain] Cd Length: 193 Bit Score: 76.12 E-value: 9.37e-17
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24582854 73 GITMEVRGLENVRKDHGAVVIMNHQSAVD---LCVLAYLWPVIGRATVVSKKEVLYIPFFGIGAWLWGTLYIDRSRKTDS 149
Cdd:cd07990 9 GVKVVVYGDEPKLPKERALIISNHRSEVDwlvLWMLADRFGRLGRLKIVLKDSLKYPPLGGWGWQLGEFIFLKRKWEKDE 88
|
90 100 110
....*....|....*....|....*....|.
gi 24582854 150 INsLQKEAKAIQERNCK--LLLFPEGTRNSK 178
Cdd:cd07990 89 KT-IKRQLKRLKDSPEPfwLLIFPEGTRFTE 118
|
|
| PLN02901 |
PLN02901 |
1-acyl-sn-glycerol-3-phosphate acyltransferase |
76-204 |
4.75e-15 |
|
1-acyl-sn-glycerol-3-phosphate acyltransferase
Pssm-ID: 215488 [Multi-domain] Cd Length: 214 Bit Score: 72.07 E-value: 4.75e-15
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24582854 76 MEVRGLENV-RKDHGAVVIMNHQSAVDLCVLAYLwpviGRA-TVVSKKEVLYIPFFGIGAWLWGTLYIDRSRKTDSINSL 153
Cdd:PLN02901 37 IEVEGLENLpSPDEPAVYVSNHQSFLDIYTLFHL----GRPfKFISKTSIFLIPIIGWAMYMTGHIPLKRMDRRSQLECL 112
|
90 100 110 120 130
....*....|....*....|....*....|....*....|....*....|.
gi 24582854 154 QKEAKAIQeRNCKLLLFPEGTRNSKDSLLPFKKGSFHIALQGKSPVQPVVI 204
Cdd:PLN02901 113 KRCMELLK-KGASVFFFPEGTRSKDGKLAAFKKGAFSVAAKTGVPVVPITL 162
|
|
| LPLAT_MGAT-like |
cd07987 |
Lysophospholipid Acyltransferases (LPLATs) of Glycerophospholipid Biosynthesis: MGAT-like; ... |
77-204 |
3.60e-07 |
|
Lysophospholipid Acyltransferases (LPLATs) of Glycerophospholipid Biosynthesis: MGAT-like; Lysophospholipid acyltransferase (LPLAT) superfamily member: acyltransferases of de novo and remodeling pathways of glycerophospholipid biosynthesis which catalyze the incorporation of an acyl group from either acylCoAs or acyl-acyl carrier proteins (acylACPs) into acceptors such as glycerol 3-phosphate, dihydroxyacetone phosphate or lyso-phosphatidic acid. Included in this suubgroup are such LPLATs as 2-acylglycerol O-acyltransferase (MGAT), and similar proteins.
Pssm-ID: 153249 [Multi-domain] Cd Length: 212 Bit Score: 49.59 E-value: 3.60e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24582854 77 EVRGLENVRKDHGAVVIMNHQ-SAVDLCVLAYLWPVIGR-ATVVSKKEVLYIPFFGIGAWLWGTLYIDRSRKtdSINSLQ 154
Cdd:cd07987 9 EVRGLENIPDEGPALLVHPHGgLPIDGALLAAAFLLLFPgRLPRALADHFLFPLPGLRDLLRRLGAVPGSRE--NCVRLL 86
|
90 100 110 120 130
....*....|....*....|....*....|....*....|....*....|....*..
gi 24582854 155 KEAKAIqerncklLLFPEGTRNSKDS-------LLPFKKGSFHIALQGKSPVQPVVI 204
Cdd:cd07987 87 REGELV-------LIFPGGAREALKSkreeyylLWKKRKGFARLALRAGAPIVPVFT 136
|
|
| PRK06814 |
PRK06814 |
acyl-[ACP]--phospholipid O-acyltransferase; |
7-205 |
3.70e-07 |
|
acyl-[ACP]--phospholipid O-acyltransferase;
Pssm-ID: 235865 [Multi-domain] Cd Length: 1140 Bit Score: 51.12 E-value: 3.70e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24582854 7 VIGLAcVVALILSATAKAPyqmrmfFIFFGAGLIVFLCVPFMI-LRPRDYRNALFpSWCFRQLCRLvgitmEVRGLENVR 85
Cdd:PRK06814 384 VAGTI-ILALLQALGFSIP------WIILFIALANLIVAILILrLLPTNLLRDIF-SILFRAFYRV-----EVKGLENLQ 450
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24582854 86 K-DHGAVVIMNHQSAVD-LCVLAYL--WPVIGRATVVSKKevLYI-PFFgigaWLWGTLYIDRSRKTdSINSLQKEAKAI 160
Cdd:PRK06814 451 KaGKKAVIAANHVSFLDgPLLAAYLpeEPTFAIDTDIAKA--WWVkPFL----KLAKALPVDPTNPM-ATRTLIKEVQKG 523
|
170 180 190 200
....*....|....*....|....*....|....*....|....*
gi 24582854 161 QerncKLLLFPEGTRNSKDSLLPFKKGSFHIALQGKSPVQPVVIS 205
Cdd:PRK06814 524 E----KLVIFPEGRITVTGSLMKIYDGPGMIADKAGAMVVPVRID 564
|
|
| PLN02380 |
PLN02380 |
1-acyl-sn-glycerol-3-phosphate acyltransferase |
32-182 |
5.33e-07 |
|
1-acyl-sn-glycerol-3-phosphate acyltransferase
Pssm-ID: 178006 [Multi-domain] Cd Length: 376 Bit Score: 50.12 E-value: 5.33e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24582854 32 FIFFGAGLIVFL--CVPFMILRP---RDYR--NALFPSWCFRQLCRLV----GITMEV----RGLENVRKDHgAVVIMNH 96
Cdd:PLN02380 14 LLFLLSGLIVNLiqAVCFILVRPlskSLYRriNRAVAELLWLELIWLVdwwaGVKVQLyadeETFELMGKEH-ALVISNH 92
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24582854 97 QSAVDLCV---LAYLWPVIGRATVVSKKEVLYIPFFGIGAWLWGTLYIDRSRKTDSiNSLQKEAKAIQE--RNCKLLLFP 171
Cdd:PLN02380 93 RSDIDWLVgwiLAQRSGCLGSALAVMKKSSKFLPVIGWSMWFSEYVFLERSWAKDE-NTLKSGFQRLKDfpRPFWLALFV 171
|
170
....*....|.
gi 24582854 172 EGTRNSKDSLL 182
Cdd:PLN02380 172 EGTRFTQAKLL 182
|
|
| PRK14014 |
PRK14014 |
putative acyltransferase; Provisional |
77-134 |
5.78e-07 |
|
putative acyltransferase; Provisional
Pssm-ID: 237584 [Multi-domain] Cd Length: 301 Bit Score: 49.85 E-value: 5.78e-07
10 20 30 40 50 60
....*....|....*....|....*....|....*....|....*....|....*....|..
gi 24582854 77 EVRGLENVRKDHGAVVIMNHQSAVDLCVLAYLW----PVIgraTVVSKKEVLYIPFFGIGAW 134
Cdd:PRK14014 76 DVEGLEGLSKKGWYLVISNHQSWVDILVLQYVFnrriPML---KFFLKQELIWVPFLGLAWW 134
|
|
| LPLAT_AAK14816-like |
cd07992 |
Lysophospholipid Acyltransferases (LPLATs) of Glycerophospholipid Biosynthesis: Unknown ... |
75-252 |
1.17e-06 |
|
Lysophospholipid Acyltransferases (LPLATs) of Glycerophospholipid Biosynthesis: Unknown AAK14816-like; Lysophospholipid acyltransferase (LPLAT) superfamily member: acyltransferases of de novo and remodeling pathways of glycerophospholipid biosynthesis which catalyze the incorporation of an acyl group from either acylCoAs or acyl-acyl carrier proteins (acylACPs) into acceptors such as glycerol 3-phosphate, dihydroxyacetone phosphate or lyso-phosphatidic acid. Included in this subgroup are uncharacterized glycerol-3-phosphate acyltransferases such as the Plasmodium falciparum locus AAK14816 putative acyltransferase, and similar proteins.
Pssm-ID: 153254 [Multi-domain] Cd Length: 203 Bit Score: 48.03 E-value: 1.17e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24582854 75 TMEVRGLENVRKDHGAVVIMNHQ-SAVDLCVLAYLWPVIGRATVVSKkeVLYIPFFGIGAWLWGTLYIDRSR-------- 145
Cdd:cd07992 15 RITVVGRENVPKDGPVIFLGNHPnALIDPLLLAATLRRPVRFLAKAD--LFKNPLIGWLLESFGAIPVYRPKdlarggig 92
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24582854 146 KTDSINSLQKEAKAIQERNCkLLLFPEGTRNSKDSLLPFKKGSFHIALQG-KSPVQPVVISKYSFMDDEKKTFRpGHAL- 223
Cdd:cd07992 93 KISNAAVFDAVGEALKAGGA-IGIFPEGGSHDRPRLLPLKAGAARMALEAlEAGQKDVKIVPVGLNYEDKSRFR-SRVLv 170
|
170 180 190
....*....|....*....|....*....|....
gi 24582854 224 -----IHILPEVSTEKYkREDVQLLIDECQSIMQ 252
Cdd:cd07992 171 efgkpISVSAFEEAEAS-RDVEKKLINQLEAELE 203
|
|
| LPLAT_ABO13168-like |
cd07988 |
Lysophospholipid Acyltransferases (LPLATs) of Glycerophospholipid Biosynthesis: Unknown ... |
65-221 |
2.17e-06 |
|
Lysophospholipid Acyltransferases (LPLATs) of Glycerophospholipid Biosynthesis: Unknown ABO13168; Lysophospholipid acyltransferase (LPLAT) superfamily member: acyltransferases of de novo and remodeling pathways of glycerophospholipid biosynthesis which catalyze the incorporation of an acyl group from either acylCoAs or acyl-acyl carrier proteins (acylACPs) into acceptors such as glycerol 3-phosphate, dihydroxyacetone phosphate or lyso-phosphatidic acid. Included in this subgroup are uncharacterized phospholipid/glycerol acyltransferases such as the Acinetobacter baumannii ATCC 17978 locus ABO13168 putative acyltransferase, and similar proteins.
Pssm-ID: 153250 [Multi-domain] Cd Length: 163 Bit Score: 46.44 E-value: 2.17e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24582854 65 FRQLCRLVGITMEVRgLENVRKdhgAVVIMN-HQSAVD-LCVLAYLWpVIGRATVVSKKEVLYIPFFGigaWL---WGTL 139
Cdd:cd07988 1 ARLLLRLSGWRIEGE-PPNKPK---FVVIGApHTSNWDfVLGLLAAF-ALGLKISFLGKHSLFKPPLG---PFmrwLGGI 72
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24582854 140 YIDRSRKTDSInslqKEAKAIQERNCKLLLF--PEGTRNSKDsllPFKKGSFHIALQGKSPVQPVviskysFMDDEKKTF 217
Cdd:cd07988 73 PVDRSRAGGLV----EQVVEEFRRREEFVLAiaPEGTRSKVD---KWKTGFYHIARGAGVPILLV------YLDYKRKTV 139
|
....
gi 24582854 218 RPGH 221
Cdd:cd07988 140 GIGP 143
|
|
| PRK08633 |
PRK08633 |
2-acyl-glycerophospho-ethanolamine acyltransferase; Validated |
32-219 |
2.52e-04 |
|
2-acyl-glycerophospho-ethanolamine acyltransferase; Validated
Pssm-ID: 236315 [Multi-domain] Cd Length: 1146 Bit Score: 42.22 E-value: 2.52e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24582854 32 FIFFGAGLIVFLCVPFMILRprdyrnaLFPSWCFRQLCRLvgitmEVRGLENVRKDHGAVVIMNHQSAVDlcvlaylWPV 111
Cdd:PRK08633 397 LVTLIGTLYTLLLLPDSLLR-------FLLLLLMHTRYRL-----RVEGRENIPAKGGALLLGNHVSWID-------WAL 457
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24582854 112 IGRAT-----VVSKKEVLYIPFFGIGAWLWGTLYIDRsrkTDSINSLQKEAKAIQERN--CkllLFPEG--TRNSkdSLL 182
Cdd:PRK08633 458 LQAASprpirFVMERSIYEKWYLKWFFKLFGVIPISS---GGSKESLEFIRKALDDGEvvC---IFPEGaiTRNG--QLN 529
|
170 180 190 200
....*....|....*....|....*....|....*....|...
gi 24582854 183 PFKKGsFHIALQGKS-PVQPVVI-----SKYSFMDDEKKTFRP 219
Cdd:PRK08633 530 EFKRG-FELIVKGTDvPIIPFYIrglwgSIFSRASGKFLWRWP 571
|
|
| PLN02510 |
PLN02510 |
probable 1-acyl-sn-glycerol-3-phosphate acyltransferase |
9-174 |
2.38e-03 |
|
probable 1-acyl-sn-glycerol-3-phosphate acyltransferase
Pssm-ID: 178126 [Multi-domain] Cd Length: 374 Bit Score: 38.91 E-value: 2.38e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24582854 9 GLACVVALILSAtakapYQMRMFFIFFGAGLIVFlcvpFMILRPRDYRNALFPSWC--FRQLCRLVGITMEVRGLENVRK 86
Cdd:PLN02510 20 GLICLLVLLSTA-----FMMLVYLAPVSAVLLRL----FSVHYSRKATSFFFGSWLalWPFLFEKINKTKVVFSGDKVPP 90
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24582854 87 DHGAVVIMNHQSAVDLcvlAYLWPV------IGRATVVSKKEVLYIPFFGIGAWLWGTLYIDRSRKTDSINSLQKEAKAI 160
Cdd:PLN02510 91 EERVLLIANHRTEVDW---MYLWDLalrkgcLGYIKYVLKSSLMKLPVFGWAFHIFEFIPVERKWEVDEPNIRQMLSSFK 167
|
170
....*....|....*
gi 24582854 161 QERN-CKLLLFPEGT 174
Cdd:PLN02510 168 DPRDpLWLALFPEGT 182
|
|
| |
