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Conserved domains on  [gi|24586278|ref|NP_610289|]
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az2 [Drosophila melanogaster]

Protein Classification

MADF_DNA_bdg domain-containing protein( domain architecture ID 11187647)

MADF_DNA_bdg domain-containing protein

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
MADF_DNA_bdg pfam10545
Alcohol dehydrogenase transcription factor Myb/SANT-like; The myb/SANT-like domain in Adf-1 ...
 157-242 4.04e-17

Alcohol dehydrogenase transcription factor Myb/SANT-like; The myb/SANT-like domain in Adf-1 (MADF) is an approximately 80-amino-acid module that directs sequence specific DNA binding to a site consisting of multiple tri-nucleotide repeats. The MADF domain is found in one or more copies in eukaryotic and viral proteins and is often associated with the BESS domain. It is likely that the MADF domain is more closely related to the myb/SANT domain than it is to other HTH domains.


:

Pssm-ID: 463144  Cd Length: 84  Bit Score: 76.17  E-value: 4.04e-17
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24586278   157 FIELYKQQTCLWDPADESYRDKEKRANAYEELLEQLKATVNLHltayKLKKCITSLHAQYASISRQKKTQ--KLTKVPLY 234
Cdd:pfam10545   1 LIELVREHPCLWDRSHPDYRNRDARERAWEEIAEELGSDVPVE----DCKKRWKNLRDQYRRELRRKRTNsgELYKSRWY 76


                  ....*...
gi 24586278   235 YHGKYSFL 242
Cdd:pfam10545  77 YYEELSFL 84
MADF_DNA_bdg super family cl48096
Alcohol dehydrogenase transcription factor Myb/SANT-like; The myb/SANT-like domain in Adf-1 ...
 276-341 1.61e-04

Alcohol dehydrogenase transcription factor Myb/SANT-like; The myb/SANT-like domain in Adf-1 (MADF) is an approximately 80-amino-acid module that directs sequence specific DNA binding to a site consisting of multiple tri-nucleotide repeats. The MADF domain is found in one or more copies in eukaryotic and viral proteins and is often associated with the BESS domain. It is likely that the MADF domain is more closely related to the myb/SANT domain than it is to other HTH domains.


The actual alignment was detected with superfamily member pfam10545:

Pssm-ID: 463144  Cd Length: 84  Bit Score: 40.73  E-value: 1.61e-04
                          10        20        30        40        50        60
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 24586278   276 FIDLYSKFPQLYDPAHKHFCNLNVRKSSLIEITDLLTSEFSLGlvthyDVYDSIQSMRQWYSRRIK 341
Cdd:pfam10545   1 LIELVREHPCLWDRSHPDYRNRDARERAWEEIAEELGSDVPVE-----DCKKRWKNLRDQYRRELR 61
 
Name Accession Description Interval E-value
MADF_DNA_bdg pfam10545
Alcohol dehydrogenase transcription factor Myb/SANT-like; The myb/SANT-like domain in Adf-1 ...
 157-242 4.04e-17

Alcohol dehydrogenase transcription factor Myb/SANT-like; The myb/SANT-like domain in Adf-1 (MADF) is an approximately 80-amino-acid module that directs sequence specific DNA binding to a site consisting of multiple tri-nucleotide repeats. The MADF domain is found in one or more copies in eukaryotic and viral proteins and is often associated with the BESS domain. It is likely that the MADF domain is more closely related to the myb/SANT domain than it is to other HTH domains.


Pssm-ID: 463144  Cd Length: 84  Bit Score: 76.17  E-value: 4.04e-17
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24586278   157 FIELYKQQTCLWDPADESYRDKEKRANAYEELLEQLKATVNLHltayKLKKCITSLHAQYASISRQKKTQ--KLTKVPLY 234
Cdd:pfam10545   1 LIELVREHPCLWDRSHPDYRNRDARERAWEEIAEELGSDVPVE----DCKKRWKNLRDQYRRELRRKRTNsgELYKSRWY 76


                  ....*...
gi 24586278   235 YHGKYSFL 242
Cdd:pfam10545  77 YYEELSFL 84
MADF smart00595
subfamily of SANT domain;
156-242 7.06e-10

subfamily of SANT domain;


Pssm-ID: 214738  Cd Length: 89  Bit Score: 55.83  E-value: 7.06e-10
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24586278    156 QFIELYKQQTCLWDPADESYRDKEKRANAYEELLEQLKATVNlhltayKLKKCITSLHAQYASISRQKKTQKLT--KVPL 233
Cdd:smart00595   1 RLIELVRERPCLWDRRHPDYRNKEEKRKAWEEIAEELGLSVE------ECKKRWKNLRDRYRRELKRLQNGKSGggKKSK 74

                           90
                   ....*....|
gi 24586278    234 YYHGKY-SFL 242
Cdd:smart00595  75 WEYFDRlSFL 84
MADF_DNA_bdg pfam10545
Alcohol dehydrogenase transcription factor Myb/SANT-like; The myb/SANT-like domain in Adf-1 ...
 276-341 1.61e-04

Alcohol dehydrogenase transcription factor Myb/SANT-like; The myb/SANT-like domain in Adf-1 (MADF) is an approximately 80-amino-acid module that directs sequence specific DNA binding to a site consisting of multiple tri-nucleotide repeats. The MADF domain is found in one or more copies in eukaryotic and viral proteins and is often associated with the BESS domain. It is likely that the MADF domain is more closely related to the myb/SANT domain than it is to other HTH domains.


Pssm-ID: 463144  Cd Length: 84  Bit Score: 40.73  E-value: 1.61e-04
                          10        20        30        40        50        60
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 24586278   276 FIDLYSKFPQLYDPAHKHFCNLNVRKSSLIEITDLLTSEFSLGlvthyDVYDSIQSMRQWYSRRIK 341
Cdd:pfam10545   1 LIELVREHPCLWDRSHPDYRNRDARERAWEEIAEELGSDVPVE-----DCKKRWKNLRDQYRRELR 61
 
Name Accession Description Interval E-value
MADF_DNA_bdg pfam10545
Alcohol dehydrogenase transcription factor Myb/SANT-like; The myb/SANT-like domain in Adf-1 ...
 157-242 4.04e-17

Alcohol dehydrogenase transcription factor Myb/SANT-like; The myb/SANT-like domain in Adf-1 (MADF) is an approximately 80-amino-acid module that directs sequence specific DNA binding to a site consisting of multiple tri-nucleotide repeats. The MADF domain is found in one or more copies in eukaryotic and viral proteins and is often associated with the BESS domain. It is likely that the MADF domain is more closely related to the myb/SANT domain than it is to other HTH domains.


Pssm-ID: 463144  Cd Length: 84  Bit Score: 76.17  E-value: 4.04e-17
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24586278   157 FIELYKQQTCLWDPADESYRDKEKRANAYEELLEQLKATVNLHltayKLKKCITSLHAQYASISRQKKTQ--KLTKVPLY 234
Cdd:pfam10545   1 LIELVREHPCLWDRSHPDYRNRDARERAWEEIAEELGSDVPVE----DCKKRWKNLRDQYRRELRRKRTNsgELYKSRWY 76


                  ....*...
gi 24586278   235 YHGKYSFL 242
Cdd:pfam10545  77 YYEELSFL 84
MADF smart00595
subfamily of SANT domain;
156-242 7.06e-10

subfamily of SANT domain;


Pssm-ID: 214738  Cd Length: 89  Bit Score: 55.83  E-value: 7.06e-10
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24586278    156 QFIELYKQQTCLWDPADESYRDKEKRANAYEELLEQLKATVNlhltayKLKKCITSLHAQYASISRQKKTQKLT--KVPL 233
Cdd:smart00595   1 RLIELVRERPCLWDRRHPDYRNKEEKRKAWEEIAEELGLSVE------ECKKRWKNLRDRYRRELKRLQNGKSGggKKSK 74

                           90
                   ....*....|
gi 24586278    234 YYHGKY-SFL 242
Cdd:smart00595  75 WEYFDRlSFL 84
MADF_DNA_bdg pfam10545
Alcohol dehydrogenase transcription factor Myb/SANT-like; The myb/SANT-like domain in Adf-1 ...
 276-341 1.61e-04

Alcohol dehydrogenase transcription factor Myb/SANT-like; The myb/SANT-like domain in Adf-1 (MADF) is an approximately 80-amino-acid module that directs sequence specific DNA binding to a site consisting of multiple tri-nucleotide repeats. The MADF domain is found in one or more copies in eukaryotic and viral proteins and is often associated with the BESS domain. It is likely that the MADF domain is more closely related to the myb/SANT domain than it is to other HTH domains.


Pssm-ID: 463144  Cd Length: 84  Bit Score: 40.73  E-value: 1.61e-04
                          10        20        30        40        50        60
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 24586278   276 FIDLYSKFPQLYDPAHKHFCNLNVRKSSLIEITDLLTSEFSLGlvthyDVYDSIQSMRQWYSRRIK 341
Cdd:pfam10545   1 LIELVREHPCLWDRSHPDYRNRDARERAWEEIAEELGSDVPVE-----DCKKRWKNLRDQYRRELR 61
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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