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Conserved domains on  [gi|24662993|ref|NP_648520|]
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Coiled-coil domain containing protein 151 [Drosophila melanogaster]

Protein Classification

coiled-coil domain-containing protein( domain architecture ID 1000037)

coiled-coil domain-containing protein contains a region with alpha-helical coiled-coil sequence signatures that is being annotated by a variety of protein family models, not necessarily indicating family membership

Graphical summary

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List of domain hits

Name Accession Description Interval E-value
COG4913 super family cl25907
Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];
209-391 5.12e-05

Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];


The actual alignment was detected with superfamily member COG4913:

Pssm-ID: 443941 [Multi-domain]  Cd Length: 1089  Bit Score: 46.45  E-value: 5.12e-05
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24662993  209 ERFERSLRELEASLSDQKAEIERLQQVHNEAVEMRDAAKVILQRQEQQANVSQKTRERQAL-DFRKQVEARKLELERIGR 287
Cdd:COG4913  613 AALEAELAELEEELAEAEERLEALEAELDALQERREALQRLAEYSWDEIDVASAEREIAELeAELERLDASSDDLAALEE 692
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24662993  288 KLFAETKTLVHQDSvgsssgDQHTAKTENGEEEpvSQLESVTSDMESLFKQLMEASGATSPFEVF---ERFSAQKESAAR 364
Cdd:COG4913  693 QLEELEAELEELEE------ELDELKGEIGRLE--KELEQAEEELDELQDRLEAAEDLARLELRAlleERFAAALGDAVE 764
                        170       180
                 ....*....|....*....|....*..
gi 24662993  365 lNYLRKAAEAEKANLEAEREALSSELE 391
Cdd:COG4913  765 -RELRENLEERIDALRARLNRAEEELE 790
PTZ00121 super family cl31754
MAEBL; Provisional
2-465 1.52e-03

MAEBL; Provisional


The actual alignment was detected with superfamily member PTZ00121:

Pssm-ID: 173412 [Multi-domain]  Cd Length: 2084  Bit Score: 41.67  E-value: 1.52e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24662993     2 ESDKLNELNRQINEIKKRIllAEGQKTANAAEWQKQNRINCDTISSLKKDIKEQTIRASRLRNPLQRpvviKESTGESRR 81
Cdd:PTZ00121 1306 EAKKKAEEAKKADEAKKKA--EEAKKKADAAKKKAEEAKKAAEAAKAEAEAAADEAEAAEEKAEAAE----KKKEEAKKK 1379
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24662993    82 AQSCTPTLIVGKATYPVGAKNADDAIFLTDLK-ITESRKQMDLLRHR---FKSRQQYFSKLVEKYRGLLANKEAQNQNMG 157
Cdd:PTZ00121 1380 ADAAKKKAEEKKKADEAKKKAEEDKKKADELKkAAAAKKKADEAKKKaeeKKKADEAKKKAEEAKKADEAKKKAEEAKKA 1459
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24662993   158 EKPPETLEEDANRKLVCQLENEIHRTNVQWMEAEHIRKKYRSI--------EASLMTDAERfERSLRELEASLSDQKAEI 229
Cdd:PTZ00121 1460 EEAKKKAEEAKKADEAKKKAEEAKKADEAKKKAEEAKKKADEAkkaaeakkKADEAKKAEE-AKKADEAKKAEEAKKADE 1538
                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24662993   230 ERLQQVHNEAVEMRDAAKVILQRQEQQANVSQKTRERQALDFRKQVEARKLELERIGRKL-FAETKTLVHQDSVGSSSGD 308
Cdd:PTZ00121 1539 AKKAEEKKKADELKKAEELKKAEEKKKAEEAKKAEEDKNMALRKAEEAKKAEEARIEEVMkLYEEEKKMKAEEAKKAEEA 1618
                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24662993   309 QHTAKTENGEEEPVSQLESVTSDMESLFKQLMEASGATSPFEVFERFSAQKESAARlnylRKAAEAEKANLE---AEREA 385
Cdd:PTZ00121 1619 KIKAEELKKAEEEKKKVEQLKKKEAEEKKKAEELKKAEEENKIKAAEEAKKAEEDK----KKAEEAKKAEEDekkAAEAL 1694
                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24662993   386 LSSELEASKFSDV---------------KESEVNQEVIEQIKNsiaaKEQDRKLDTDEAGKSMGVLKYLKERICEMIFKV 450
Cdd:PTZ00121 1695 KKEAEEAKKAEELkkkeaeekkkaeelkKAEEENKIKAEEAKK----EAEEDKKKAEEAKKDEEEKKKIAHLKKEEEKKA 1770
                         490
                  ....*....|....*
gi 24662993   451 QEVDESNIEIPERKL 465
Cdd:PTZ00121 1771 EEIRKEKEAVIEEEL 1785
 
Name Accession Description Interval E-value
COG4913 COG4913
Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];
209-391 5.12e-05

Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];


Pssm-ID: 443941 [Multi-domain]  Cd Length: 1089  Bit Score: 46.45  E-value: 5.12e-05
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24662993  209 ERFERSLRELEASLSDQKAEIERLQQVHNEAVEMRDAAKVILQRQEQQANVSQKTRERQAL-DFRKQVEARKLELERIGR 287
Cdd:COG4913  613 AALEAELAELEEELAEAEERLEALEAELDALQERREALQRLAEYSWDEIDVASAEREIAELeAELERLDASSDDLAALEE 692
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24662993  288 KLFAETKTLVHQDSvgsssgDQHTAKTENGEEEpvSQLESVTSDMESLFKQLMEASGATSPFEVF---ERFSAQKESAAR 364
Cdd:COG4913  693 QLEELEAELEELEE------ELDELKGEIGRLE--KELEQAEEELDELQDRLEAAEDLARLELRAlleERFAAALGDAVE 764
                        170       180
                 ....*....|....*....|....*..
gi 24662993  365 lNYLRKAAEAEKANLEAEREALSSELE 391
Cdd:COG4913  765 -RELRENLEERIDALRARLNRAEEELE 790
PTZ00121 PTZ00121
MAEBL; Provisional
2-465 1.52e-03

MAEBL; Provisional


Pssm-ID: 173412 [Multi-domain]  Cd Length: 2084  Bit Score: 41.67  E-value: 1.52e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24662993     2 ESDKLNELNRQINEIKKRIllAEGQKTANAAEWQKQNRINCDTISSLKKDIKEQTIRASRLRNPLQRpvviKESTGESRR 81
Cdd:PTZ00121 1306 EAKKKAEEAKKADEAKKKA--EEAKKKADAAKKKAEEAKKAAEAAKAEAEAAADEAEAAEEKAEAAE----KKKEEAKKK 1379
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24662993    82 AQSCTPTLIVGKATYPVGAKNADDAIFLTDLK-ITESRKQMDLLRHR---FKSRQQYFSKLVEKYRGLLANKEAQNQNMG 157
Cdd:PTZ00121 1380 ADAAKKKAEEKKKADEAKKKAEEDKKKADELKkAAAAKKKADEAKKKaeeKKKADEAKKKAEEAKKADEAKKKAEEAKKA 1459
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24662993   158 EKPPETLEEDANRKLVCQLENEIHRTNVQWMEAEHIRKKYRSI--------EASLMTDAERfERSLRELEASLSDQKAEI 229
Cdd:PTZ00121 1460 EEAKKKAEEAKKADEAKKKAEEAKKADEAKKKAEEAKKKADEAkkaaeakkKADEAKKAEE-AKKADEAKKAEEAKKADE 1538
                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24662993   230 ERLQQVHNEAVEMRDAAKVILQRQEQQANVSQKTRERQALDFRKQVEARKLELERIGRKL-FAETKTLVHQDSVGSSSGD 308
Cdd:PTZ00121 1539 AKKAEEKKKADELKKAEELKKAEEKKKAEEAKKAEEDKNMALRKAEEAKKAEEARIEEVMkLYEEEKKMKAEEAKKAEEA 1618
                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24662993   309 QHTAKTENGEEEPVSQLESVTSDMESLFKQLMEASGATSPFEVFERFSAQKESAARlnylRKAAEAEKANLE---AEREA 385
Cdd:PTZ00121 1619 KIKAEELKKAEEEKKKVEQLKKKEAEEKKKAEELKKAEEENKIKAAEEAKKAEEDK----KKAEEAKKAEEDekkAAEAL 1694
                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24662993   386 LSSELEASKFSDV---------------KESEVNQEVIEQIKNsiaaKEQDRKLDTDEAGKSMGVLKYLKERICEMIFKV 450
Cdd:PTZ00121 1695 KKEAEEAKKAEELkkkeaeekkkaeelkKAEEENKIKAEEAKK----EAEEDKKKAEEAKKDEEEKKKIAHLKKEEEKKA 1770
                         490
                  ....*....|....*
gi 24662993   451 QEVDESNIEIPERKL 465
Cdd:PTZ00121 1771 EEIRKEKEAVIEEEL 1785
SMC_prok_B TIGR02168
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...
170-477 3.98e-03

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274008 [Multi-domain]  Cd Length: 1179  Bit Score: 40.43  E-value: 3.98e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24662993    170 RKLVCQLENEIHRTNVQWMEAEHIRKKYRSIEASLMTDAERFERSLRELEASLSDQKAEIERLQQVHNEAVEMRDAAKVI 249
Cdd:TIGR02168  704 RKELEELEEELEQLRKELEELSRQISALRKDLARLEAEVEQLEERIAQLSKELTELEAEIEELEERLEEAEEELAEAEAE 783
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24662993    250 LQRQEQQANvsqktrerQALDFRKQVEARKLELERIgrklFAETKTLVHQDSVGSSSGDQHTAKTENGEEEPVSQLESVT 329
Cdd:TIGR02168  784 IEELEAQIE--------QLKEELKALREALDELRAE----LTLLNEEAANLRERLESLERRIAATERRLEDLEEQIEELS 851
                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24662993    330 SDMESLFKQLmeasgatspfevferfSAQKESAARLNYLRKAAEAEKANLEAEREALSSELEAskfSDVKESEVNQEVIE 409
Cdd:TIGR02168  852 EDIESLAAEI----------------EELEELIEELESELEALLNERASLEEALALLRSELEE---LSEELRELESKRSE 912
                          250       260       270       280       290       300       310
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 24662993    410 QIKNSIAAKEQDRKLDTDEAGKSMGvLKYLKERICE---MIFKVQEVDESNIEIPERKLHVSVAELPNFLA 477
Cdd:TIGR02168  913 LRRELEELREKLAQLELRLEGLEVR-IDNLQERLSEeysLTLEEAEALENKIEDDEEEARRRLKRLENKIK 982
PRK02224 PRK02224
DNA double-strand break repair Rad50 ATPase;
215-392 8.86e-03

DNA double-strand break repair Rad50 ATPase;


Pssm-ID: 179385 [Multi-domain]  Cd Length: 880  Bit Score: 39.25  E-value: 8.86e-03
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24662993  215 LRELEASLSDQKAEIERLQQVHNEAVEMRDAAKVILQRQEQ---------------QANVSQKTRERQALDFRKQV-EAR 278
Cdd:PRK02224 208 LNGLESELAELDEEIERYEEQREQARETRDEADEVLEEHEErreeletleaeiedlRETIAETEREREELAEEVRDlRER 287
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24662993  279 KLELERIGRKLFAETKTlvhqDSVGSSSGDQHTAKTENGEEEPVSQLESVTSDMESLFKQLMEASGATSPFEvfERFSAQ 358
Cdd:PRK02224 288 LEELEEERDDLLAEAGL----DDADAEAVEARREELEDRDEELRDRLEECRVAAQAHNEEAESLREDADDLE--ERAEEL 361
                        170       180       190
                 ....*....|....*....|....*....|....
gi 24662993  359 KESAARLNYLRKAAEAEKANLEAEREALSSELEA 392
Cdd:PRK02224 362 REEAAELESELEEAREAVEDRREEIEELEEEIEE 395
 
Name Accession Description Interval E-value
COG4913 COG4913
Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];
209-391 5.12e-05

Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];


Pssm-ID: 443941 [Multi-domain]  Cd Length: 1089  Bit Score: 46.45  E-value: 5.12e-05
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24662993  209 ERFERSLRELEASLSDQKAEIERLQQVHNEAVEMRDAAKVILQRQEQQANVSQKTRERQAL-DFRKQVEARKLELERIGR 287
Cdd:COG4913  613 AALEAELAELEEELAEAEERLEALEAELDALQERREALQRLAEYSWDEIDVASAEREIAELeAELERLDASSDDLAALEE 692
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24662993  288 KLFAETKTLVHQDSvgsssgDQHTAKTENGEEEpvSQLESVTSDMESLFKQLMEASGATSPFEVF---ERFSAQKESAAR 364
Cdd:COG4913  693 QLEELEAELEELEE------ELDELKGEIGRLE--KELEQAEEELDELQDRLEAAEDLARLELRAlleERFAAALGDAVE 764
                        170       180
                 ....*....|....*....|....*..
gi 24662993  365 lNYLRKAAEAEKANLEAEREALSSELE 391
Cdd:COG4913  765 -RELRENLEERIDALRARLNRAEEELE 790
Smc COG1196
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ...
111-437 7.98e-05

Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 440809 [Multi-domain]  Cd Length: 983  Bit Score: 45.70  E-value: 7.98e-05
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24662993 111 DLKITESRKQMDLLRHRFKSRQQYFSKLVEKYRGLLANKEAQNQNMGEKppETLEEDANRKLVcQLENEIHRTNVQWMEA 190
Cdd:COG1196 217 ELKEELKELEAELLLLKLRELEAELEELEAELEELEAELEELEAELAEL--EAELEELRLELE-ELELELEEAQAEEYEL 293
                        90       100       110       120       130       140       150       160
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24662993 191 EHIRKKYRSIEASLMTDAERFERSLRELEASLSDQKAEIERLQQVHNEAVEMRDAAKVILQRQEQQANVSQKTRERQALD 270
Cdd:COG1196 294 LAELARLEQDIARLEERRRELEERLEELEEELAELEEELEELEEELEELEEELEEAEEELEEAEAELAEAEEALLEAEAE 373
                       170       180       190       200       210       220       230       240
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24662993 271 FRKQVEARKLELERIGRKLfaetktlvhqdsvgsssgdQHTAKTENGEEEPVSQLESVTSDMESLFKQLMEASgatspfe 350
Cdd:COG1196 374 LAEAEEELEELAEELLEAL-------------------RAAAELAAQLEELEEAEEALLERLERLEEELEELE------- 427
                       250       260       270       280       290       300       310       320
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24662993 351 vfERFSAQKESAARLNYLRKAAEAEKANLEAEREALSSELEASKFSDVKESEVNQEVIEQIKNSIAAKEQDRKLDTDEAG 430
Cdd:COG1196 428 --EALAELEEEEEEEEEALEEAAEEEAELEEEEEALLELLAELLEEAALLEAALAELLEELAEAAARLLLLLEAEADYEG 505

                ....*..
gi 24662993 431 KSMGVLK 437
Cdd:COG1196 506 FLEGVKA 512
PTZ00121 PTZ00121
MAEBL; Provisional
2-465 1.52e-03

MAEBL; Provisional


Pssm-ID: 173412 [Multi-domain]  Cd Length: 2084  Bit Score: 41.67  E-value: 1.52e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24662993     2 ESDKLNELNRQINEIKKRIllAEGQKTANAAEWQKQNRINCDTISSLKKDIKEQTIRASRLRNPLQRpvviKESTGESRR 81
Cdd:PTZ00121 1306 EAKKKAEEAKKADEAKKKA--EEAKKKADAAKKKAEEAKKAAEAAKAEAEAAADEAEAAEEKAEAAE----KKKEEAKKK 1379
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24662993    82 AQSCTPTLIVGKATYPVGAKNADDAIFLTDLK-ITESRKQMDLLRHR---FKSRQQYFSKLVEKYRGLLANKEAQNQNMG 157
Cdd:PTZ00121 1380 ADAAKKKAEEKKKADEAKKKAEEDKKKADELKkAAAAKKKADEAKKKaeeKKKADEAKKKAEEAKKADEAKKKAEEAKKA 1459
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24662993   158 EKPPETLEEDANRKLVCQLENEIHRTNVQWMEAEHIRKKYRSI--------EASLMTDAERfERSLRELEASLSDQKAEI 229
Cdd:PTZ00121 1460 EEAKKKAEEAKKADEAKKKAEEAKKADEAKKKAEEAKKKADEAkkaaeakkKADEAKKAEE-AKKADEAKKAEEAKKADE 1538
                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24662993   230 ERLQQVHNEAVEMRDAAKVILQRQEQQANVSQKTRERQALDFRKQVEARKLELERIGRKL-FAETKTLVHQDSVGSSSGD 308
Cdd:PTZ00121 1539 AKKAEEKKKADELKKAEELKKAEEKKKAEEAKKAEEDKNMALRKAEEAKKAEEARIEEVMkLYEEEKKMKAEEAKKAEEA 1618
                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24662993   309 QHTAKTENGEEEPVSQLESVTSDMESLFKQLMEASGATSPFEVFERFSAQKESAARlnylRKAAEAEKANLE---AEREA 385
Cdd:PTZ00121 1619 KIKAEELKKAEEEKKKVEQLKKKEAEEKKKAEELKKAEEENKIKAAEEAKKAEEDK----KKAEEAKKAEEDekkAAEAL 1694
                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24662993   386 LSSELEASKFSDV---------------KESEVNQEVIEQIKNsiaaKEQDRKLDTDEAGKSMGVLKYLKERICEMIFKV 450
Cdd:PTZ00121 1695 KKEAEEAKKAEELkkkeaeekkkaeelkKAEEENKIKAEEAKK----EAEEDKKKAEEAKKDEEEKKKIAHLKKEEEKKA 1770
                         490
                  ....*....|....*
gi 24662993   451 QEVDESNIEIPERKL 465
Cdd:PTZ00121 1771 EEIRKEKEAVIEEEL 1785
SMC_prok_B TIGR02168
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...
170-477 3.98e-03

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274008 [Multi-domain]  Cd Length: 1179  Bit Score: 40.43  E-value: 3.98e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24662993    170 RKLVCQLENEIHRTNVQWMEAEHIRKKYRSIEASLMTDAERFERSLRELEASLSDQKAEIERLQQVHNEAVEMRDAAKVI 249
Cdd:TIGR02168  704 RKELEELEEELEQLRKELEELSRQISALRKDLARLEAEVEQLEERIAQLSKELTELEAEIEELEERLEEAEEELAEAEAE 783
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24662993    250 LQRQEQQANvsqktrerQALDFRKQVEARKLELERIgrklFAETKTLVHQDSVGSSSGDQHTAKTENGEEEPVSQLESVT 329
Cdd:TIGR02168  784 IEELEAQIE--------QLKEELKALREALDELRAE----LTLLNEEAANLRERLESLERRIAATERRLEDLEEQIEELS 851
                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24662993    330 SDMESLFKQLmeasgatspfevferfSAQKESAARLNYLRKAAEAEKANLEAEREALSSELEAskfSDVKESEVNQEVIE 409
Cdd:TIGR02168  852 EDIESLAAEI----------------EELEELIEELESELEALLNERASLEEALALLRSELEE---LSEELRELESKRSE 912
                          250       260       270       280       290       300       310
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 24662993    410 QIKNSIAAKEQDRKLDTDEAGKSMGvLKYLKERICE---MIFKVQEVDESNIEIPERKLHVSVAELPNFLA 477
Cdd:TIGR02168  913 LRRELEELREKLAQLELRLEGLEVR-IDNLQERLSEeysLTLEEAEALENKIEDDEEEARRRLKRLENKIK 982
PRK02224 PRK02224
DNA double-strand break repair Rad50 ATPase;
215-392 8.86e-03

DNA double-strand break repair Rad50 ATPase;


Pssm-ID: 179385 [Multi-domain]  Cd Length: 880  Bit Score: 39.25  E-value: 8.86e-03
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24662993  215 LRELEASLSDQKAEIERLQQVHNEAVEMRDAAKVILQRQEQ---------------QANVSQKTRERQALDFRKQV-EAR 278
Cdd:PRK02224 208 LNGLESELAELDEEIERYEEQREQARETRDEADEVLEEHEErreeletleaeiedlRETIAETEREREELAEEVRDlRER 287
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24662993  279 KLELERIGRKLFAETKTlvhqDSVGSSSGDQHTAKTENGEEEPVSQLESVTSDMESLFKQLMEASGATSPFEvfERFSAQ 358
Cdd:PRK02224 288 LEELEEERDDLLAEAGL----DDADAEAVEARREELEDRDEELRDRLEECRVAAQAHNEEAESLREDADDLE--ERAEEL 361
                        170       180       190
                 ....*....|....*....|....*....|....
gi 24662993  359 KESAARLNYLRKAAEAEKANLEAEREALSSELEA 392
Cdd:PRK02224 362 REEAAELESELEEAREAVEDRREEIEELEEEIEE 395
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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