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Conserved domains on  [gi|24645930|ref|NP_650070|]
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ninaG, isoform A [Drosophila melanogaster]

Protein Classification

GMC family oxidoreductase( domain architecture ID 11455227)

GMC (glucose-methanol-choline) family oxidoreductase is a flavoprotein that catalyzes the oxidation of an alcohol moiety to the corresponding aldehyde with the concomitant reduction of flavin adenine dinucleotide (FAD)

EC:  1.-.-.-
Gene Ontology:  GO:0016491|GO:0050660
PubMed:  23578136|1542121
SCOP:  3000055

Graphical summary

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List of domain hits

Name Accession Description Interval E-value
BetA COG2303
Choline dehydrogenase or related flavoprotein [Lipid transport and metabolism, General ...
66-593 1.52e-94

Choline dehydrogenase or related flavoprotein [Lipid transport and metabolism, General function prediction only]; Choline dehydrogenase or related flavoprotein is part of the Pathway/BioSystem: Non-phosphorylated Entner-Doudoroff pathway


:

Pssm-ID: 441878 [Multi-domain]  Cd Length: 531  Bit Score: 299.82  E-value: 1.52e-94
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24645930  66 AKNSNGSVLLIEAGG-QFGLLSRIPLLTTFQQKG-INDWSFLSVPQKHssrgLIERRQCLPRGKGLGGSANLNYMLHFDG 143
Cdd:COG2303  24 SEDAGLRVLLLEAGGrDDDPLIRMPAGYAKLLGNpRYDWRYETEPQPG----LNGRRLYWPRGKVLGGSSSINGMIYVRG 99
                        90       100       110       120       130       140       150       160
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24645930 144 HGPDFDSWRdHHNLSDWSWAQMR-------SFMAAAKP----KNPDMLEIPRRYSKLTEALEEA---------------- 196
Cdd:COG2303 100 QPEDFDLWA-QLGNQGWGYDDVLpyfkraeDNERGADAyhgrSGPLPVSDPPLPNPLSDAFIEAaeelgipraddfngga 178
                       170       180       190       200       210       220       230       240
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24645930 197 QAQFAYkdwiFRrslYNIRNGLRHSVVQQFLNPVIHHSNLRLLPDALVKRIQLAPSpflQATSILVgikdeENREKEFSI 276
Cdd:COG2303 179 CEGCGF----CQ---VTCRNGARWSAARAYLPPALKRPNLTVRTGALVTRILFDGG---RATGVEY-----RDDGEEHTV 243
                       250       260       270       280       290       300       310       320
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24645930 277 EVRRELILCAGAYQTPQLLMASGIGDVSALKKLGIPAQHSLPLVGHNLHDHFNLPlfVSMGVTGPTLNQNTLLNPMTLIN 356
Cdd:COG2303 244 RAAREVILAAGAINSPQLLLLSGIGPASHLREHGIPVVHDLPGVGRNLQDHLEVS--VVFRFKEPVTLNKSLRKARIGLQ 321
                       330       340       350       360       370       380       390       400
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24645930 357 YLSSGSGPLgnfgvLGNVVSYGGlgappygitFF-GAGAIDESALMSIsnFKGPAFRALFPRYYNSSQEGFVVISSCLQP 435
Cdd:COG2303 322 YLLTRSGPL-----TSNVAEAGG---------FFrSDPGLERPDLQFH--FLPLGLTPRWGKKALHDGHGFTAHVEQLRP 385
                       410       420       430       440       450       460       470       480
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24645930 436 KSRGSVGLLNRHMRRNPLIDPNYLSSEEDVACTISAIRSAVELVNSTAFAALHPRIHWPRvqecsnfgpferdffDNRPS 515
Cdd:COG2303 386 ESRGRVTLDSADPLGAPLIRPNYLSDENDRRVLVAGVRLAREIAAQPALAPYRGEEILPG---------------PDVQS 450
                       490       500       510       520       530       540       550       560
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24645930 516 DQYLECLMRHVGlGSHHPGGTCALG----SVVDSQLRLKGVSNVRVVDASVLPRPISGNPNSVVVAIALRAASWILKSEL 591
Cdd:COG2303 451 DEELAFIRARAY-TIYHPVGTCRMGtdpdSVVDPRLRVHGVENLRVVDASVMPTITSGNTNAPTIMLAEKAADMILGDYL 529

                ..
gi 24645930 592 QA 593
Cdd:COG2303 530 KN 531
 
Name Accession Description Interval E-value
BetA COG2303
Choline dehydrogenase or related flavoprotein [Lipid transport and metabolism, General ...
66-593 1.52e-94

Choline dehydrogenase or related flavoprotein [Lipid transport and metabolism, General function prediction only]; Choline dehydrogenase or related flavoprotein is part of the Pathway/BioSystem: Non-phosphorylated Entner-Doudoroff pathway


Pssm-ID: 441878 [Multi-domain]  Cd Length: 531  Bit Score: 299.82  E-value: 1.52e-94
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24645930  66 AKNSNGSVLLIEAGG-QFGLLSRIPLLTTFQQKG-INDWSFLSVPQKHssrgLIERRQCLPRGKGLGGSANLNYMLHFDG 143
Cdd:COG2303  24 SEDAGLRVLLLEAGGrDDDPLIRMPAGYAKLLGNpRYDWRYETEPQPG----LNGRRLYWPRGKVLGGSSSINGMIYVRG 99
                        90       100       110       120       130       140       150       160
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24645930 144 HGPDFDSWRdHHNLSDWSWAQMR-------SFMAAAKP----KNPDMLEIPRRYSKLTEALEEA---------------- 196
Cdd:COG2303 100 QPEDFDLWA-QLGNQGWGYDDVLpyfkraeDNERGADAyhgrSGPLPVSDPPLPNPLSDAFIEAaeelgipraddfngga 178
                       170       180       190       200       210       220       230       240
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24645930 197 QAQFAYkdwiFRrslYNIRNGLRHSVVQQFLNPVIHHSNLRLLPDALVKRIQLAPSpflQATSILVgikdeENREKEFSI 276
Cdd:COG2303 179 CEGCGF----CQ---VTCRNGARWSAARAYLPPALKRPNLTVRTGALVTRILFDGG---RATGVEY-----RDDGEEHTV 243
                       250       260       270       280       290       300       310       320
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24645930 277 EVRRELILCAGAYQTPQLLMASGIGDVSALKKLGIPAQHSLPLVGHNLHDHFNLPlfVSMGVTGPTLNQNTLLNPMTLIN 356
Cdd:COG2303 244 RAAREVILAAGAINSPQLLLLSGIGPASHLREHGIPVVHDLPGVGRNLQDHLEVS--VVFRFKEPVTLNKSLRKARIGLQ 321
                       330       340       350       360       370       380       390       400
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24645930 357 YLSSGSGPLgnfgvLGNVVSYGGlgappygitFF-GAGAIDESALMSIsnFKGPAFRALFPRYYNSSQEGFVVISSCLQP 435
Cdd:COG2303 322 YLLTRSGPL-----TSNVAEAGG---------FFrSDPGLERPDLQFH--FLPLGLTPRWGKKALHDGHGFTAHVEQLRP 385
                       410       420       430       440       450       460       470       480
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24645930 436 KSRGSVGLLNRHMRRNPLIDPNYLSSEEDVACTISAIRSAVELVNSTAFAALHPRIHWPRvqecsnfgpferdffDNRPS 515
Cdd:COG2303 386 ESRGRVTLDSADPLGAPLIRPNYLSDENDRRVLVAGVRLAREIAAQPALAPYRGEEILPG---------------PDVQS 450
                       490       500       510       520       530       540       550       560
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24645930 516 DQYLECLMRHVGlGSHHPGGTCALG----SVVDSQLRLKGVSNVRVVDASVLPRPISGNPNSVVVAIALRAASWILKSEL 591
Cdd:COG2303 451 DEELAFIRARAY-TIYHPVGTCRMGtdpdSVVDPRLRVHGVENLRVVDASVMPTITSGNTNAPTIMLAEKAADMILGDYL 529

                ..
gi 24645930 592 QA 593
Cdd:COG2303 530 KN 531
PRK02106 PRK02106
choline dehydrogenase; Validated
47-587 2.36e-65

choline dehydrogenase; Validated


Pssm-ID: 235000 [Multi-domain]  Cd Length: 560  Bit Score: 223.55  E-value: 2.36e-65
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24645930   47 FDYVIVGGGTGGSTLTSLLAKNSNGSVLLIEAGG---QFGLLSRIP--LLTTFQQKgINDWSFLSVPQKHssrgLIERRQ 121
Cdd:PRK02106   6 YDYIIIGAGSAGCVLANRLSEDPDVSVLLLEAGGpdyRWDFFIQMPaaLAFPLQGK-RYNWAYETEPEPH----MNNRRM 80
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24645930  122 CLPRGKGLGGSANLNYMLHFDGHGPDFDSWRDHHNLSDWSWA-------QMRSFMAAAKP----------------KNPd 178
Cdd:PRK02106  81 ECPRGKVLGGSSSINGMVYIRGNAMDYDNWAELPGLEGWSYAdclpyfkKAETRDGGEDDyrggdgplsvtrgkpgTNP- 159
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24645930  179 mleiprryskLTEALEEA--QAQFAYKDwifrrsLYN-------------IRNGLRHSVVQQFLNPVIHHSNLRLLPDAL 243
Cdd:PRK02106 160 ----------LFQAFVEAgvQAGYPRTD------DLNgyqqegfgpmdrtVTNGRRWSAARAYLDPALKRPNLTIVTHAL 223
                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24645930  244 VKRIQLAPSpflQAtsilVGIKDEENREKEfSIEVRRELILCAGAYQTPQLLMASGIGDVSALKKLGIPAQHSLPLVGHN 323
Cdd:PRK02106 224 TDRILFEGK---RA----VGVEYERGGGRE-TARARREVILSAGAINSPQLLQLSGIGPAEHLKELGIPVVHDLPGVGEN 295
                        330       340       350       360       370       380       390       400
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24645930  324 LHDHfnLPLFVSMGVTGP-TLN-QNTLLN-PMTLINYLSSGSgplgnfgvlgnvvsygGLGAPpygiTFFGAGAIdesaL 400
Cdd:PRK02106 296 LQDH--LEVYIQYECKQPvSLYpALKWWNkPKIGAEWLFTGT----------------GLGAS----NHFEAGGF----I 349
                        410       420       430       440       450       460       470       480
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24645930  401 MSISNFKGP---------AFRalfpryYNSSQ----EGFVVISSCLQPKSRGSVGLLNRHMRRNPLIDPNYLSSEEDVAC 467
Cdd:PRK02106 350 RSRAGVDWPniqyhflpvAIR------YDGSNavkgHGFQAHVGPMRSPSRGSVKLKSADPRAHPSILFNYMSTEQDWRE 423
                        490       500       510       520       530       540       550       560
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24645930  468 TISAIRSAVELVNSTAFAALHPRIHWP--RVQecsnfgpferdffdnrpSDQYLECLMRHVGLGSHHPGGTCALG----S 541
Cdd:PRK02106 424 FRDAIRLTREIMAQPALDPYRGREISPgaDVQ-----------------TDEEIDAFVREHAETAYHPSCTCKMGtdpmA 486
                        570       580       590       600
                 ....*....|....*....|....*....|....*....|....*.
gi 24645930  542 VVDSQLRLKGVSNVRVVDASVLPRPISGNPNSVVVAIALRAASWIL 587
Cdd:PRK02106 487 VVDPEGRVHGVEGLRVVDASIMPTITNGNLNAPTIMIAEKAADLIR 532
GMC_oxred_C pfam05199
GMC oxidoreductase; This domain found associated with pfam00732.
435-582 7.09e-35

GMC oxidoreductase; This domain found associated with pfam00732.


Pssm-ID: 398739 [Multi-domain]  Cd Length: 143  Bit Score: 128.67  E-value: 7.09e-35
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24645930   435 PKSRGSVGLLNRHMRRNPLIDPNYLSSEEDVACTISAIRSAVELVNSTAFAALHPRIhwprvqecsnFGPFERDFFDNRP 514
Cdd:pfam05199   1 PRSRGRVTLSSSDPTGLPVIDPNYLSDPADLAALRAALRLARRILAAAGLVLGVELT----------PGPVPEVSDAAVT 70
                          90       100       110       120       130       140       150
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 24645930   515 SDQYLECLMRHVGLGSHHPGGTCALG-----SVVDSQLRLKGVSNVRVVDASVLPRPISGNPNSVVVAIALRA 582
Cdd:pfam05199  71 SDDELLAYIRAAASTSYHPMGTCRMGadpddAVVDPDLRVHGVDNLRVVDASVFPSSPSGNPTLTIYALAERA 143
 
Name Accession Description Interval E-value
BetA COG2303
Choline dehydrogenase or related flavoprotein [Lipid transport and metabolism, General ...
66-593 1.52e-94

Choline dehydrogenase or related flavoprotein [Lipid transport and metabolism, General function prediction only]; Choline dehydrogenase or related flavoprotein is part of the Pathway/BioSystem: Non-phosphorylated Entner-Doudoroff pathway


Pssm-ID: 441878 [Multi-domain]  Cd Length: 531  Bit Score: 299.82  E-value: 1.52e-94
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24645930  66 AKNSNGSVLLIEAGG-QFGLLSRIPLLTTFQQKG-INDWSFLSVPQKHssrgLIERRQCLPRGKGLGGSANLNYMLHFDG 143
Cdd:COG2303  24 SEDAGLRVLLLEAGGrDDDPLIRMPAGYAKLLGNpRYDWRYETEPQPG----LNGRRLYWPRGKVLGGSSSINGMIYVRG 99
                        90       100       110       120       130       140       150       160
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24645930 144 HGPDFDSWRdHHNLSDWSWAQMR-------SFMAAAKP----KNPDMLEIPRRYSKLTEALEEA---------------- 196
Cdd:COG2303 100 QPEDFDLWA-QLGNQGWGYDDVLpyfkraeDNERGADAyhgrSGPLPVSDPPLPNPLSDAFIEAaeelgipraddfngga 178
                       170       180       190       200       210       220       230       240
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24645930 197 QAQFAYkdwiFRrslYNIRNGLRHSVVQQFLNPVIHHSNLRLLPDALVKRIQLAPSpflQATSILVgikdeENREKEFSI 276
Cdd:COG2303 179 CEGCGF----CQ---VTCRNGARWSAARAYLPPALKRPNLTVRTGALVTRILFDGG---RATGVEY-----RDDGEEHTV 243
                       250       260       270       280       290       300       310       320
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24645930 277 EVRRELILCAGAYQTPQLLMASGIGDVSALKKLGIPAQHSLPLVGHNLHDHFNLPlfVSMGVTGPTLNQNTLLNPMTLIN 356
Cdd:COG2303 244 RAAREVILAAGAINSPQLLLLSGIGPASHLREHGIPVVHDLPGVGRNLQDHLEVS--VVFRFKEPVTLNKSLRKARIGLQ 321
                       330       340       350       360       370       380       390       400
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24645930 357 YLSSGSGPLgnfgvLGNVVSYGGlgappygitFF-GAGAIDESALMSIsnFKGPAFRALFPRYYNSSQEGFVVISSCLQP 435
Cdd:COG2303 322 YLLTRSGPL-----TSNVAEAGG---------FFrSDPGLERPDLQFH--FLPLGLTPRWGKKALHDGHGFTAHVEQLRP 385
                       410       420       430       440       450       460       470       480
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24645930 436 KSRGSVGLLNRHMRRNPLIDPNYLSSEEDVACTISAIRSAVELVNSTAFAALHPRIHWPRvqecsnfgpferdffDNRPS 515
Cdd:COG2303 386 ESRGRVTLDSADPLGAPLIRPNYLSDENDRRVLVAGVRLAREIAAQPALAPYRGEEILPG---------------PDVQS 450
                       490       500       510       520       530       540       550       560
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24645930 516 DQYLECLMRHVGlGSHHPGGTCALG----SVVDSQLRLKGVSNVRVVDASVLPRPISGNPNSVVVAIALRAASWILKSEL 591
Cdd:COG2303 451 DEELAFIRARAY-TIYHPVGTCRMGtdpdSVVDPRLRVHGVENLRVVDASVMPTITSGNTNAPTIMLAEKAADMILGDYL 529

                ..
gi 24645930 592 QA 593
Cdd:COG2303 530 KN 531
PRK02106 PRK02106
choline dehydrogenase; Validated
47-587 2.36e-65

choline dehydrogenase; Validated


Pssm-ID: 235000 [Multi-domain]  Cd Length: 560  Bit Score: 223.55  E-value: 2.36e-65
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24645930   47 FDYVIVGGGTGGSTLTSLLAKNSNGSVLLIEAGG---QFGLLSRIP--LLTTFQQKgINDWSFLSVPQKHssrgLIERRQ 121
Cdd:PRK02106   6 YDYIIIGAGSAGCVLANRLSEDPDVSVLLLEAGGpdyRWDFFIQMPaaLAFPLQGK-RYNWAYETEPEPH----MNNRRM 80
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24645930  122 CLPRGKGLGGSANLNYMLHFDGHGPDFDSWRDHHNLSDWSWA-------QMRSFMAAAKP----------------KNPd 178
Cdd:PRK02106  81 ECPRGKVLGGSSSINGMVYIRGNAMDYDNWAELPGLEGWSYAdclpyfkKAETRDGGEDDyrggdgplsvtrgkpgTNP- 159
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24645930  179 mleiprryskLTEALEEA--QAQFAYKDwifrrsLYN-------------IRNGLRHSVVQQFLNPVIHHSNLRLLPDAL 243
Cdd:PRK02106 160 ----------LFQAFVEAgvQAGYPRTD------DLNgyqqegfgpmdrtVTNGRRWSAARAYLDPALKRPNLTIVTHAL 223
                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24645930  244 VKRIQLAPSpflQAtsilVGIKDEENREKEfSIEVRRELILCAGAYQTPQLLMASGIGDVSALKKLGIPAQHSLPLVGHN 323
Cdd:PRK02106 224 TDRILFEGK---RA----VGVEYERGGGRE-TARARREVILSAGAINSPQLLQLSGIGPAEHLKELGIPVVHDLPGVGEN 295
                        330       340       350       360       370       380       390       400
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24645930  324 LHDHfnLPLFVSMGVTGP-TLN-QNTLLN-PMTLINYLSSGSgplgnfgvlgnvvsygGLGAPpygiTFFGAGAIdesaL 400
Cdd:PRK02106 296 LQDH--LEVYIQYECKQPvSLYpALKWWNkPKIGAEWLFTGT----------------GLGAS----NHFEAGGF----I 349
                        410       420       430       440       450       460       470       480
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24645930  401 MSISNFKGP---------AFRalfpryYNSSQ----EGFVVISSCLQPKSRGSVGLLNRHMRRNPLIDPNYLSSEEDVAC 467
Cdd:PRK02106 350 RSRAGVDWPniqyhflpvAIR------YDGSNavkgHGFQAHVGPMRSPSRGSVKLKSADPRAHPSILFNYMSTEQDWRE 423
                        490       500       510       520       530       540       550       560
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24645930  468 TISAIRSAVELVNSTAFAALHPRIHWP--RVQecsnfgpferdffdnrpSDQYLECLMRHVGLGSHHPGGTCALG----S 541
Cdd:PRK02106 424 FRDAIRLTREIMAQPALDPYRGREISPgaDVQ-----------------TDEEIDAFVREHAETAYHPSCTCKMGtdpmA 486
                        570       580       590       600
                 ....*....|....*....|....*....|....*....|....*.
gi 24645930  542 VVDSQLRLKGVSNVRVVDASVLPRPISGNPNSVVVAIALRAASWIL 587
Cdd:PRK02106 487 VVDPEGRVHGVEGLRVVDASIMPTITNGNLNAPTIMIAEKAADLIR 532
GMC_oxred_C pfam05199
GMC oxidoreductase; This domain found associated with pfam00732.
435-582 7.09e-35

GMC oxidoreductase; This domain found associated with pfam00732.


Pssm-ID: 398739 [Multi-domain]  Cd Length: 143  Bit Score: 128.67  E-value: 7.09e-35
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24645930   435 PKSRGSVGLLNRHMRRNPLIDPNYLSSEEDVACTISAIRSAVELVNSTAFAALHPRIhwprvqecsnFGPFERDFFDNRP 514
Cdd:pfam05199   1 PRSRGRVTLSSSDPTGLPVIDPNYLSDPADLAALRAALRLARRILAAAGLVLGVELT----------PGPVPEVSDAAVT 70
                          90       100       110       120       130       140       150
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 24645930   515 SDQYLECLMRHVGLGSHHPGGTCALG-----SVVDSQLRLKGVSNVRVVDASVLPRPISGNPNSVVVAIALRA 582
Cdd:pfam05199  71 SDDELLAYIRAAASTSYHPMGTCRMGadpddAVVDPDLRVHGVDNLRVVDASVFPSSPSGNPTLTIYALAERA 143
GMC_oxred_N pfam00732
GMC oxidoreductase; This family of proteins bind FAD as a cofactor.
119-327 9.56e-24

GMC oxidoreductase; This family of proteins bind FAD as a cofactor.


Pssm-ID: 366272 [Multi-domain]  Cd Length: 218  Bit Score: 99.66  E-value: 9.56e-24
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24645930   119 RRQCLPRGKGLGGSANLNYMLHFDGHGPDFDSWRDHHNLSDWSWAQMRSFMaaakpknpDMLEIP-------RRYSKLTE 191
Cdd:pfam00732  17 RRMILPAGSTVGGGSSVNWSACIRTPAAVLDEWASEFGLEGWGYDDYLPYM--------DKVEGPlgvttkgIEESPLNQ 88
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24645930   192 ALEEAQAQFAYKDWIFRRSL----------YNIRNGLRHSVVQQFLNPVIHHsNLRLLPDALVKRIQlapspFLQATSIL 261
Cdd:pfam00732  89 ALLKAAEELGYPVEAVPRNSngchycgfcgLGCPTGAKQSTARTWLRPALER-NLRILTGAKAEKII-----ILGRGGRA 162
                         170       180       190       200       210       220
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 24645930   262 VGI--KDEENREKEFSIEvRRELILCAGAYQTPQLLMASGIGdvsalkklgiPAQHSlplVGHNLHDH 327
Cdd:pfam00732 163 VGVeaRDGGGGIKRLITA-AKEVVVAAGALNTPPLLLRSGLG----------KNPHP---VGKNLQLH 216
PLN02785 PLN02785
Protein HOTHEAD
215-576 1.35e-15

Protein HOTHEAD


Pssm-ID: 215420 [Multi-domain]  Cd Length: 587  Bit Score: 79.85  E-value: 1.35e-15
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24645930  215 RNGLRHSVVQqfLNPVIHHSNLRLLPDALVKRIqLAPSPFLQATSILVGIKDEE-NREKEFSIEVRR-ELILCAGAYQTP 292
Cdd:PLN02785 216 EFGRRHTAAE--LLAAGNPNKLRVLLHATVQKI-VFDTSGKRPRATGVIFKDENgNQHQAFLSNNKGsEIILSAGAIGSP 292
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24645930  293 QLLMASGIGDVSALKKLGIPAQHSLPLVGHNLHDHfnlPLfvsmgvtgptlnqNTLLNPM------TLINYLSsgsgpLG 366
Cdd:PLN02785 293 QMLLLSGIGPKKELKKHKIPVVLHNEHVGKGMADN---PM-------------NSIFVPSkapveqSLIQTVG-----IT 351
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24645930  367 NFGVLgnVVSYGGLGAPP------YGITffgAGAIDESALMSISNFKGPAFRALFPRYYNSSQEGF---VVISSCLQPKS 437
Cdd:PLN02785 352 KMGVY--IEASSGFGQSPdsihchHGIM---SAEIGQLSTIPPKQRTPEAIQAYIHRKKNLPHEAFnggFILEKIAGPIS 426
                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24645930  438 RGSVGLLNRHMRRNPLIDPNYLSSEEDVACTISAIRSAVELVNSTAFAAL-----HP--RIHWPRVQECSNFGPFERDff 510
Cdd:PLN02785 427 TGHLSLINTNVDDNPSVTFNYFKHPQDLQRCVYGIRTIEKIVKTNHFTNFtqcdkQTmeKVLNMSVKANINLIPKHTN-- 504
                        330       340       350       360       370       380
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 24645930  511 DNRPSDQYleCLMRHVGLGSHHpgGTCALGSVVDSQLRLKGVSNVRVVDASVLPRPISGNPNSVVV 576
Cdd:PLN02785 505 DTKSLEQF--CKDTVITIWHYH--GGCHVGKVVDQNYKVLGVSRLRVIDGSTFDESPGTNPQATVM 566
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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