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Conserved domains on  [gi|22748615|ref|NP_689474|]
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transmembrane protein 263 isoform a [Homo sapiens]

Protein Classification

transmembrane protein 263( domain architecture ID 10634573)

transmembrane protein 263 (TMEM263/C12orf23) is associated with bone mineral deposition in humans and autosomal dwarfism in chickens

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
UPF0444 pfam15475
Transmembrane protein C12orf23, UPF0444; This family of proteins is found in eukaryotes. ...
 25-115 6.59e-41

Transmembrane protein C12orf23, UPF0444; This family of proteins is found in eukaryotes. Proteins in this family are typically between 94 and 119 amino acids in length.


:

Pssm-ID: 464737  Cd Length: 91  Bit Score: 130.76  E-value: 6.59e-41
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 22748615    25 KDHPQQQPGMLSRVTGGIFSVTKGAVGATIGGVAWIGGKSLEVTKTAVTTVPSMGIGLVKGGVSAVAGGVTAVGSAVVNK 104
Cdd:pfam15475   1 KDHPAAQGGVLWRVTGGLFNVTKGAVGATVGGVAWVGGKSLEATKSAVTTVPEVGVGLVKGGVSAVAGGVSTVGSAVASK 80

                          90
                  ....*....|.
gi 22748615   105 VPLTGKKKDKS 115
Cdd:pfam15475  81 VPFTAKKKDKS 91
 
Name Accession Description Interval E-value
UPF0444 pfam15475
Transmembrane protein C12orf23, UPF0444; This family of proteins is found in eukaryotes. ...
 25-115 6.59e-41

Transmembrane protein C12orf23, UPF0444; This family of proteins is found in eukaryotes. Proteins in this family are typically between 94 and 119 amino acids in length.


Pssm-ID: 464737  Cd Length: 91  Bit Score: 130.76  E-value: 6.59e-41
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 22748615    25 KDHPQQQPGMLSRVTGGIFSVTKGAVGATIGGVAWIGGKSLEVTKTAVTTVPSMGIGLVKGGVSAVAGGVTAVGSAVVNK 104
Cdd:pfam15475   1 KDHPAAQGGVLWRVTGGLFNVTKGAVGATVGGVAWVGGKSLEATKSAVTTVPEVGVGLVKGGVSAVAGGVSTVGSAVASK 80

                          90
                  ....*....|.
gi 22748615   105 VPLTGKKKDKS 115
Cdd:pfam15475  81 VPFTAKKKDKS 91
 
Name Accession Description Interval E-value
UPF0444 pfam15475
Transmembrane protein C12orf23, UPF0444; This family of proteins is found in eukaryotes. ...
 25-115 6.59e-41

Transmembrane protein C12orf23, UPF0444; This family of proteins is found in eukaryotes. Proteins in this family are typically between 94 and 119 amino acids in length.


Pssm-ID: 464737  Cd Length: 91  Bit Score: 130.76  E-value: 6.59e-41
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 22748615    25 KDHPQQQPGMLSRVTGGIFSVTKGAVGATIGGVAWIGGKSLEVTKTAVTTVPSMGIGLVKGGVSAVAGGVTAVGSAVVNK 104
Cdd:pfam15475   1 KDHPAAQGGVLWRVTGGLFNVTKGAVGATVGGVAWVGGKSLEATKSAVTTVPEVGVGLVKGGVSAVAGGVSTVGSAVASK 80

                          90
                  ....*....|.
gi 22748615   105 VPLTGKKKDKS 115
Cdd:pfam15475  81 VPFTAKKKDKS 91
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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