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Conserved domains on  [gi|25777746|ref|NP_689808|]
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piggyBac transposable element-derived protein 4 [Homo sapiens]

Protein Classification

transposase; transposase family protein( domain architecture ID 10620078)

transposase binds to the end of a transposon and catalyzes the movement of the transposon to another part of the genome by a cut and paste mechanism or a replicative transposition mechanism| transposase family protein might bind to the end of a transposon and catalyze the movement of the transposon to another part of the genome by a cut and paste mechanism or a replicative transposition mechanism

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
DDE_Tnp_1_7 pfam13843
Transposase IS4;
103-468 2.28e-141

Transposase IS4;


:

Pssm-ID: 433521  Cd Length: 349  Bit Score: 413.23  E-value: 2.28e-141
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25777746   103 DPLQYFELFFTEELVSKITRETNAQAALlaskppgpkgfsrMDKWKDTDNDELKVFFAVMLLQGIVQKPELEMFWSTRPL 182
Cdd:pfam13843   1 DPVELFELFLDDEIIARIVRETNLYAKQ-------------KYKWLPLTAEELMAFLGLLILMGDVRLPSVEDYWSTKMF 67

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25777746   183 LDTPYLRQIMTGERFLLLFRCLHFVNNSSISAGQSKaqisLQKIKPVFDFLVNKFSTVYTPNRNIAVDESLMLFKGPLAM 262
Cdd:pfam13843  68 YGNPGLRDAMSRERFEFLLSALHFADNPTRKAETDK----LGKIRPLIDYLNENMQKVYRPSQTLVLDESLILFKGRVPF 143

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25777746   263 KQYLPTKRVRFGLKLYVLCESQSGYVWNALVHTGPGMNLKDSADGLKSSRIVLTLVNDLLGQGYCVFLDNFNISPMLFRE 342
Cdd:pfam13843 144 KQYLPGKPRKNGIKLHVLCDAQTGYIIALELYEGPARNGRNSRQLGKRNALVLRLTEPLQGQGRHVYFDNFYTSLDLAQE 223

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25777746   343 LHQNRTDAVGTARLNRKQIPNDLKKRIAKGTTVARFCGELMALKWCDGKEVTMLSTFHNDTVIEVNNRNGKKTKRPRVIV 422
Cdd:pfam13843 224 LAKKGTYATGTLRKNRYGLPKDLTQQLPPGSILARYGGPLMLFKWRRRKVVLLLSTFSSDCLVYSKERSGQKIARPKLVE 303

                         330       340       350       360
                  ....*....|....*....|....*....|....*....|....*.
gi 25777746   423 DYNENMGAVDSADQMLTSYPSERKRHKVWYKKFFHHLLHITVLNSY 468
Cdd:pfam13843 304 DYNQAKGAVDRHDQLLAAYRVSRKGSKKWYKRVFIFLLNIAVVNAY 349
Tnp_zf-ribbon_2 pfam13842
DDE_Tnp_1-like zinc-ribbon; This zinc-ribbon domain is frequently found at the C-terminal of ...
 539-575 8.94e-09

DDE_Tnp_1-like zinc-ribbon; This zinc-ribbon domain is frequently found at the C-terminal of proteins derived from transposable elements.


:

Pssm-ID: 404687  Cd Length: 31  Bit Score: 50.89  E-value: 8.94e-09
                          10        20        30
                  ....*....|....*....|....*....|....*..
gi 25777746   539 GRCKICCSqydkdgKKIRKETRYFCAECDVPLCVVPC 575
Cdd:pfam13842   1 GRCKVCLK------KKIKTFTRIRCQECGVPLCQNHC 31
 
Name Accession Description Interval E-value
DDE_Tnp_1_7 pfam13843
Transposase IS4;
103-468 2.28e-141

Transposase IS4;


Pssm-ID: 433521  Cd Length: 349  Bit Score: 413.23  E-value: 2.28e-141
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25777746   103 DPLQYFELFFTEELVSKITRETNAQAALlaskppgpkgfsrMDKWKDTDNDELKVFFAVMLLQGIVQKPELEMFWSTRPL 182
Cdd:pfam13843   1 DPVELFELFLDDEIIARIVRETNLYAKQ-------------KYKWLPLTAEELMAFLGLLILMGDVRLPSVEDYWSTKMF 67

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25777746   183 LDTPYLRQIMTGERFLLLFRCLHFVNNSSISAGQSKaqisLQKIKPVFDFLVNKFSTVYTPNRNIAVDESLMLFKGPLAM 262
Cdd:pfam13843  68 YGNPGLRDAMSRERFEFLLSALHFADNPTRKAETDK----LGKIRPLIDYLNENMQKVYRPSQTLVLDESLILFKGRVPF 143

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25777746   263 KQYLPTKRVRFGLKLYVLCESQSGYVWNALVHTGPGMNLKDSADGLKSSRIVLTLVNDLLGQGYCVFLDNFNISPMLFRE 342
Cdd:pfam13843 144 KQYLPGKPRKNGIKLHVLCDAQTGYIIALELYEGPARNGRNSRQLGKRNALVLRLTEPLQGQGRHVYFDNFYTSLDLAQE 223

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25777746   343 LHQNRTDAVGTARLNRKQIPNDLKKRIAKGTTVARFCGELMALKWCDGKEVTMLSTFHNDTVIEVNNRNGKKTKRPRVIV 422
Cdd:pfam13843 224 LAKKGTYATGTLRKNRYGLPKDLTQQLPPGSILARYGGPLMLFKWRRRKVVLLLSTFSSDCLVYSKERSGQKIARPKLVE 303

                         330       340       350       360
                  ....*....|....*....|....*....|....*....|....*.
gi 25777746   423 DYNENMGAVDSADQMLTSYPSERKRHKVWYKKFFHHLLHITVLNSY 468
Cdd:pfam13843 304 DYNQAKGAVDRHDQLLAAYRVSRKGSKKWYKRVFIFLLNIAVVNAY 349
Tnp_zf-ribbon_2 pfam13842
DDE_Tnp_1-like zinc-ribbon; This zinc-ribbon domain is frequently found at the C-terminal of ...
 539-575 8.94e-09

DDE_Tnp_1-like zinc-ribbon; This zinc-ribbon domain is frequently found at the C-terminal of proteins derived from transposable elements.


Pssm-ID: 404687  Cd Length: 31  Bit Score: 50.89  E-value: 8.94e-09
                          10        20        30
                  ....*....|....*....|....*....|....*..
gi 25777746   539 GRCKICCSqydkdgKKIRKETRYFCAECDVPLCVVPC 575
Cdd:pfam13842   1 GRCKVCLK------KKIKTFTRIRCQECGVPLCQNHC 31
 
Name Accession Description Interval E-value
DDE_Tnp_1_7 pfam13843
Transposase IS4;
103-468 2.28e-141

Transposase IS4;


Pssm-ID: 433521  Cd Length: 349  Bit Score: 413.23  E-value: 2.28e-141
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25777746   103 DPLQYFELFFTEELVSKITRETNAQAALlaskppgpkgfsrMDKWKDTDNDELKVFFAVMLLQGIVQKPELEMFWSTRPL 182
Cdd:pfam13843   1 DPVELFELFLDDEIIARIVRETNLYAKQ-------------KYKWLPLTAEELMAFLGLLILMGDVRLPSVEDYWSTKMF 67

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25777746   183 LDTPYLRQIMTGERFLLLFRCLHFVNNSSISAGQSKaqisLQKIKPVFDFLVNKFSTVYTPNRNIAVDESLMLFKGPLAM 262
Cdd:pfam13843  68 YGNPGLRDAMSRERFEFLLSALHFADNPTRKAETDK----LGKIRPLIDYLNENMQKVYRPSQTLVLDESLILFKGRVPF 143

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25777746   263 KQYLPTKRVRFGLKLYVLCESQSGYVWNALVHTGPGMNLKDSADGLKSSRIVLTLVNDLLGQGYCVFLDNFNISPMLFRE 342
Cdd:pfam13843 144 KQYLPGKPRKNGIKLHVLCDAQTGYIIALELYEGPARNGRNSRQLGKRNALVLRLTEPLQGQGRHVYFDNFYTSLDLAQE 223

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25777746   343 LHQNRTDAVGTARLNRKQIPNDLKKRIAKGTTVARFCGELMALKWCDGKEVTMLSTFHNDTVIEVNNRNGKKTKRPRVIV 422
Cdd:pfam13843 224 LAKKGTYATGTLRKNRYGLPKDLTQQLPPGSILARYGGPLMLFKWRRRKVVLLLSTFSSDCLVYSKERSGQKIARPKLVE 303

                         330       340       350       360
                  ....*....|....*....|....*....|....*....|....*.
gi 25777746   423 DYNENMGAVDSADQMLTSYPSERKRHKVWYKKFFHHLLHITVLNSY 468
Cdd:pfam13843 304 DYNQAKGAVDRHDQLLAAYRVSRKGSKKWYKRVFIFLLNIAVVNAY 349
Tnp_zf-ribbon_2 pfam13842
DDE_Tnp_1-like zinc-ribbon; This zinc-ribbon domain is frequently found at the C-terminal of ...
 539-575 8.94e-09

DDE_Tnp_1-like zinc-ribbon; This zinc-ribbon domain is frequently found at the C-terminal of proteins derived from transposable elements.


Pssm-ID: 404687  Cd Length: 31  Bit Score: 50.89  E-value: 8.94e-09
                          10        20        30
                  ....*....|....*....|....*....|....*..
gi 25777746   539 GRCKICCSqydkdgKKIRKETRYFCAECDVPLCVVPC 575
Cdd:pfam13842   1 GRCKVCLK------KKIKTFTRIRCQECGVPLCQNHC 31
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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