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Conserved domains on  [gi|23346557|ref|NP_694762|]
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5-oxoprolinase [Mus musculus]

Protein Classification

hydantoinase/oxoprolinase family protein( domain architecture ID 1004610)

hydantoinase/oxoprolinase family protein is involved in the hydrolysis of 5-membered rings via hydrolysis of their internal imide bonds; such as 5-oxoprolinase that catalyzes the hydrolysis of 5-oxoproline (5-OP) to L-glutamate

EC:  3.5.2.-
Gene Ontology:  GO:0005524|GO:0016812

Graphical summary

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List of domain hits

Name Accession Description Interval E-value
PLN02666 super family cl33539
5-oxoprolinase
1-1258 0e+00

5-oxoprolinase


The actual alignment was detected with superfamily member PLN02666:

Pssm-ID: 215358 [Multi-domain]  Cd Length: 1275  Bit Score: 1904.83  E-value: 0e+00
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 23346557     1 MGSPEER-FHFAIDRGGTFTDVFAQCPGG-HVRVLKLLSEDPANYADAPTEGIRRILEQERGVLLPRGRPLDTSHIASIR 78
Cdd:PLN02666    2 MGSRGSRkFRFCIDRGGTFTDVYAEVPGGsDFRVLKLLSVDPANYDDAPREGIRRILEEVTGKKIPRSAKIPTERIEWIR 81
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 23346557    79 MGTTVATNALLERQGERVALLVTRGFRDLLHIGTQARPDLFDLAVPMPEVLYEEVVEVDERVLLYRGEPGA---GSPVKG 155
Cdd:PLN02666   82 MGTTVATNALLERKGERIALCVTKGFKDLLQIGNQARPNIFDLTVSKPSNLYEEVVEVDERVVLALEEDGDdagGSVVKG 161
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 23346557   156 CTGDLLEIQQPVDLAALRGKLEGLLTRGIHSLAVVLMHSYTWAQHEQQVGTLARELGFTHVSLSSEVMPMVRIVPRGHTA 235
Cdd:PLN02666  162 VTGELVEVVKPLDEEALRPLLQGLLDKGIRSLAVVLMHSYTYPAHERAVGKLARSMGFKQVSLSSALVPMVRAVPRGHTA 241
                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 23346557   236 CADAYLTPTIQRYVQGFRRGFQGQLKNVQVLFMRSDGGLAPMDAFSGSRAVLSGPAGGVVGYSTTTYQLEGGQPVIGFDM 315
Cdd:PLN02666  242 SVDAYLTPVIKEYLSGFLSGFDDGLGDVNVLFMQSDGGLTPESRFSGHKAILSGPAGGVVGYAQTTFGLETEKPVIGFDM 321
                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 23346557   316 GGTSTDVSRYAGEFEHVFEASTAGVTLQAPQLDINTVAAGGGSRLFFRSGLFVVGPESAGAHPGPACYRKGGPVTVTDAN 395
Cdd:PLN02666  322 GGTSTDVSRYDGSYEQVLETQTAGVIIQAPQLDINTVAAGGGSKLKFQFGAFRVGPESVGAHPGPVCYRKGGELAVTDAN 401
                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 23346557   396 LVLGRLLPASFPCIFGPGEDQPLSPEASRKALEAVAMEVNSFLASGPCPASQLSLEEVAMGFVRVANEAMCRPIRALTQA 475
Cdd:PLN02666  402 LVLGRVIPDYFPSIFGPNEDEPLDLEATRAAFEALAAQINSYRKSQDPSAKDMSVEEVALGFVRVANEAMCRPIRQLTEM 481
                         490       500       510       520       530       540       550       560
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 23346557   476 RGHDPSAHVLACFGGAGGQHACAIARALGMDTVHIHRHSGLLSALGLALADVVHEAQEPCSLSYTPETFAQLDQRLSRLE 555
Cdd:PLN02666  482 KGYETANHALACFGGAGPQHACAIARALGMSEVFVHRYCGILSAYGMGLADVVAEAQEPYAAVYGPESLAEASRREDALA 561
                         570       580       590       600       610       620       630       640
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 23346557   556 EQCVDALQAQGFSRSQISTESFLHLRYQGTDCALMVSanQHPATTCSPraGDFGAAFVERYMREFGFIIPERSVVVDDVR 635
Cdd:PLN02666  562 EKVRQKLQEQGFREDNITTETYLNLRYEGTDTAIMVA--EPENGDGSD--GDYAAAFVKLFRREYGFKLQNRDILIDDVR 637
                         650       660       670       680       690       700       710       720
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 23346557   636 VRGTGRSG-LQLEETSKIQSGPPHVEKVTQCYFEGGYQETPVYLLGELGYGHQLQGPCLIIDNNSTILVEPGCQAEVIET 714
Cdd:PLN02666  638 VRGIGVTNiLKPLPLDAASGGLPEPERTTKVYFENGWHDTPVYKLENLGPGHEIPGPAIIMNGNSTVVVEPGCKAIVTKY 717
                         730       740       750       760       770       780       790       800
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 23346557   715 GDIRISVG-------AEAPSMIDTKLDPIQLSIFSHRFMSIAEQMGRILQRTAISTNIKERLDFSCALFGPDGGLVSNAP 787
Cdd:PLN02666  718 GNIKIEVEnsaeqsaEETVKAAEKKADVVQLSIFNHRFMGIAEQMGRTLQRTSISTNIKERLDFSCALFGPDGGLVANAP 797
                         810       820       830       840       850       860       870       880
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 23346557   788 HIPVHLGAMQETVQFQIQHLGADLHPGDVLLSNHPSAGGSHLPDLTVITPVFWPGqsRPVFYVASRGHHADIGGITPGSM 867
Cdd:PLN02666  798 HVPVHLGAMSSTVRWQLEYWGENLNEGDVLVTNHPQAGGSHLPDITVITPVFRDG--KIVFFVASRGHHADIGGITPGSM 875
                         890       900       910       920       930       940       950       960
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 23346557   868 PPHSTTLQQEGAVFLSFKLVQGGVFQEEAVTEALQAPGKISGC---SGTRNLHDNLSDLRAQVAANQKGIQLVGELIGQY 944
Cdd:PLN02666  876 PPFSKTIWEEGAAIKAFKLVEGGVFQEEGITKLLQAPGSDETApkiPGTRRLQDNLSDLRAQVAANQRGISLIKELIDEY 955
                         970       980       990      1000      1010      1020      1030      1040
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 23346557   945 GLDVVQAYMGHIQANAELAVRDMLRAFGT--SRQARGLPLEVS----AKDHMDDGSPICLHVQINLNQGSAVFDFSGSGS 1018
Cdd:PLN02666  956 GLGTVQAYMGHVQANAELAVREMLKSVAArvSSESPTFGDGSSvtleAEDYMDDGSPIHLTLTIDRRKGSAVFDFEGTSP 1035
                        1050      1060      1070      1080      1090      1100      1110      1120
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 23346557  1019 EVFGNLNAPRAITLSALIYCLRCLVGRDIPLNQGCLAPVQVIIPKGSILDPSPEAAVVGGNVLTSQRVVDVILGAFGACA 1098
Cdd:PLN02666 1036 EVYGNWNAPPAVTAAAVIYCLRCLVDVDIPLNQGCLAPVTIRIPPGSFLSPSDKAAVVGGNVLTSQRVTDVVLTAFQACA 1115
                        1130      1140      1150      1160      1170      1180      1190      1200
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 23346557  1099 ASQGCMNNVTLGNARMGYYETVAGGAGAGPGWHGRSGVHSHMTNTRITDPEILESRYPVILRRFELRPGSGGRGRFRGGD 1178
Cdd:PLN02666 1116 CSQGCMNNLTFGDDTFGYYETIAGGAGAGPTWDGTSGVQCHMTNTRITDPEILERRYPVLLHRFGLREGSGGDGLHRGGD 1195
                        1210      1220      1230      1240      1250      1260      1270      1280
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 23346557  1179 GVVRELVFREEALLSVLTERRAFQPYGLHGGEPGTRGLNLLIRKDGRTVNLGGKTSVTVYPGDAFCLHTPGGGGYGDPED 1258
Cdd:PLN02666 1196 GVVREIEFRRPVTVSILSERRVHAPRGLAGGGDGARGANLLIRKDGRRVNLGGKNTVHVEAGERLRILTPGGGGYGSKPS 1275
 
Name Accession Description Interval E-value
PLN02666 PLN02666
5-oxoprolinase
1-1258 0e+00

5-oxoprolinase


Pssm-ID: 215358 [Multi-domain]  Cd Length: 1275  Bit Score: 1904.83  E-value: 0e+00
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 23346557     1 MGSPEER-FHFAIDRGGTFTDVFAQCPGG-HVRVLKLLSEDPANYADAPTEGIRRILEQERGVLLPRGRPLDTSHIASIR 78
Cdd:PLN02666    2 MGSRGSRkFRFCIDRGGTFTDVYAEVPGGsDFRVLKLLSVDPANYDDAPREGIRRILEEVTGKKIPRSAKIPTERIEWIR 81
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 23346557    79 MGTTVATNALLERQGERVALLVTRGFRDLLHIGTQARPDLFDLAVPMPEVLYEEVVEVDERVLLYRGEPGA---GSPVKG 155
Cdd:PLN02666   82 MGTTVATNALLERKGERIALCVTKGFKDLLQIGNQARPNIFDLTVSKPSNLYEEVVEVDERVVLALEEDGDdagGSVVKG 161
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 23346557   156 CTGDLLEIQQPVDLAALRGKLEGLLTRGIHSLAVVLMHSYTWAQHEQQVGTLARELGFTHVSLSSEVMPMVRIVPRGHTA 235
Cdd:PLN02666  162 VTGELVEVVKPLDEEALRPLLQGLLDKGIRSLAVVLMHSYTYPAHERAVGKLARSMGFKQVSLSSALVPMVRAVPRGHTA 241
                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 23346557   236 CADAYLTPTIQRYVQGFRRGFQGQLKNVQVLFMRSDGGLAPMDAFSGSRAVLSGPAGGVVGYSTTTYQLEGGQPVIGFDM 315
Cdd:PLN02666  242 SVDAYLTPVIKEYLSGFLSGFDDGLGDVNVLFMQSDGGLTPESRFSGHKAILSGPAGGVVGYAQTTFGLETEKPVIGFDM 321
                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 23346557   316 GGTSTDVSRYAGEFEHVFEASTAGVTLQAPQLDINTVAAGGGSRLFFRSGLFVVGPESAGAHPGPACYRKGGPVTVTDAN 395
Cdd:PLN02666  322 GGTSTDVSRYDGSYEQVLETQTAGVIIQAPQLDINTVAAGGGSKLKFQFGAFRVGPESVGAHPGPVCYRKGGELAVTDAN 401
                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 23346557   396 LVLGRLLPASFPCIFGPGEDQPLSPEASRKALEAVAMEVNSFLASGPCPASQLSLEEVAMGFVRVANEAMCRPIRALTQA 475
Cdd:PLN02666  402 LVLGRVIPDYFPSIFGPNEDEPLDLEATRAAFEALAAQINSYRKSQDPSAKDMSVEEVALGFVRVANEAMCRPIRQLTEM 481
                         490       500       510       520       530       540       550       560
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 23346557   476 RGHDPSAHVLACFGGAGGQHACAIARALGMDTVHIHRHSGLLSALGLALADVVHEAQEPCSLSYTPETFAQLDQRLSRLE 555
Cdd:PLN02666  482 KGYETANHALACFGGAGPQHACAIARALGMSEVFVHRYCGILSAYGMGLADVVAEAQEPYAAVYGPESLAEASRREDALA 561
                         570       580       590       600       610       620       630       640
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 23346557   556 EQCVDALQAQGFSRSQISTESFLHLRYQGTDCALMVSanQHPATTCSPraGDFGAAFVERYMREFGFIIPERSVVVDDVR 635
Cdd:PLN02666  562 EKVRQKLQEQGFREDNITTETYLNLRYEGTDTAIMVA--EPENGDGSD--GDYAAAFVKLFRREYGFKLQNRDILIDDVR 637
                         650       660       670       680       690       700       710       720
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 23346557   636 VRGTGRSG-LQLEETSKIQSGPPHVEKVTQCYFEGGYQETPVYLLGELGYGHQLQGPCLIIDNNSTILVEPGCQAEVIET 714
Cdd:PLN02666  638 VRGIGVTNiLKPLPLDAASGGLPEPERTTKVYFENGWHDTPVYKLENLGPGHEIPGPAIIMNGNSTVVVEPGCKAIVTKY 717
                         730       740       750       760       770       780       790       800
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 23346557   715 GDIRISVG-------AEAPSMIDTKLDPIQLSIFSHRFMSIAEQMGRILQRTAISTNIKERLDFSCALFGPDGGLVSNAP 787
Cdd:PLN02666  718 GNIKIEVEnsaeqsaEETVKAAEKKADVVQLSIFNHRFMGIAEQMGRTLQRTSISTNIKERLDFSCALFGPDGGLVANAP 797
                         810       820       830       840       850       860       870       880
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 23346557   788 HIPVHLGAMQETVQFQIQHLGADLHPGDVLLSNHPSAGGSHLPDLTVITPVFWPGqsRPVFYVASRGHHADIGGITPGSM 867
Cdd:PLN02666  798 HVPVHLGAMSSTVRWQLEYWGENLNEGDVLVTNHPQAGGSHLPDITVITPVFRDG--KIVFFVASRGHHADIGGITPGSM 875
                         890       900       910       920       930       940       950       960
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 23346557   868 PPHSTTLQQEGAVFLSFKLVQGGVFQEEAVTEALQAPGKISGC---SGTRNLHDNLSDLRAQVAANQKGIQLVGELIGQY 944
Cdd:PLN02666  876 PPFSKTIWEEGAAIKAFKLVEGGVFQEEGITKLLQAPGSDETApkiPGTRRLQDNLSDLRAQVAANQRGISLIKELIDEY 955
                         970       980       990      1000      1010      1020      1030      1040
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 23346557   945 GLDVVQAYMGHIQANAELAVRDMLRAFGT--SRQARGLPLEVS----AKDHMDDGSPICLHVQINLNQGSAVFDFSGSGS 1018
Cdd:PLN02666  956 GLGTVQAYMGHVQANAELAVREMLKSVAArvSSESPTFGDGSSvtleAEDYMDDGSPIHLTLTIDRRKGSAVFDFEGTSP 1035
                        1050      1060      1070      1080      1090      1100      1110      1120
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 23346557  1019 EVFGNLNAPRAITLSALIYCLRCLVGRDIPLNQGCLAPVQVIIPKGSILDPSPEAAVVGGNVLTSQRVVDVILGAFGACA 1098
Cdd:PLN02666 1036 EVYGNWNAPPAVTAAAVIYCLRCLVDVDIPLNQGCLAPVTIRIPPGSFLSPSDKAAVVGGNVLTSQRVTDVVLTAFQACA 1115
                        1130      1140      1150      1160      1170      1180      1190      1200
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 23346557  1099 ASQGCMNNVTLGNARMGYYETVAGGAGAGPGWHGRSGVHSHMTNTRITDPEILESRYPVILRRFELRPGSGGRGRFRGGD 1178
Cdd:PLN02666 1116 CSQGCMNNLTFGDDTFGYYETIAGGAGAGPTWDGTSGVQCHMTNTRITDPEILERRYPVLLHRFGLREGSGGDGLHRGGD 1195
                        1210      1220      1230      1240      1250      1260      1270      1280
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 23346557  1179 GVVRELVFREEALLSVLTERRAFQPYGLHGGEPGTRGLNLLIRKDGRTVNLGGKTSVTVYPGDAFCLHTPGGGGYGDPED 1258
Cdd:PLN02666 1196 GVVREIEFRRPVTVSILSERRVHAPRGLAGGGDGARGANLLIRKDGRRVNLGGKNTVHVEAGERLRILTPGGGGYGSKPS 1275
Hydantoinase_B pfam02538
Hydantoinase B/oxoprolinase; This family includes N-methylhydaintoinase B which converts ...
735-1256 0e+00

Hydantoinase B/oxoprolinase; This family includes N-methylhydaintoinase B which converts hydantoin to N-carbamyl-amino acids, and 5-oxoprolinase EC:3.5.2.9 which catalyzes the formation of L-glutamate from 5-oxo-L-proline. These enzymes are part of the oxoprolinase family and are related to pfam01968.


Pssm-ID: 460583  Cd Length: 507  Bit Score: 687.28  E-value: 0e+00
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 23346557    735 PIQLSIFSHRFMSIAEQMGRILQRTAISTNIKERLDFSCALFGPDGGLVSNAPHIPVHLGAMQETVQFQIQHLGaDLHPG 814
Cdd:pfam02538    1 PITLEVFRNRLMSIAEEMGRTLQRTAFSPNIKERLDFSCAIFDADGRLVAQAPHIPVHLGSMSFAVKAVIEYGG-DLRPG 79
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 23346557    815 DVLLSNHPSAGGSHLPDLTVITPVFWPGqsRPVFYVASRGHHADIGGITPGSMPPHSTTLQQEGAVFLSFKLVQGGVfQE 894
Cdd:pfam02538   80 DVFITNDPYAGGTHLPDITVITPVFHDG--ELVFFVASRGHHADIGGIVPGSMPPDATEIYQEGLRIPPVKLVRRGV-LN 156
                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 23346557    895 EAVTEALqapgkisgCSGTRNLHDNLSDLRAQVAANQKGIQLVGELIGQYGLDVVQAYMGHIQANAELAVRDMLRAfgts 974
Cdd:pfam02538  157 EDVLRLL--------LANSRTPEDNLGDLKAQIAANRVGERRLLELIDEYGLDTVLAAMDEIQDYAERAVRAAIAA---- 224
                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 23346557    975 rqargLPL-EVSAKDHMDDGSPICLHVQINLNQGSAVFDFSGSGSEVFGNLNAPRAITLSALIYCLRCLVGRDIPLNQGC 1053
Cdd:pfam02538  225 -----LPDgTYEAEDYLDDGVPIPIRVTVTIDGDEATVDFTGTSPQVPGNINAPLAVTHSAVIYALRCLVDPDIPLNAGC 299
                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 23346557   1054 LAPVQVIIPKGSILDPSPEAAVVGGNVLTSQRVVDVILGAFG------ACAASQGCMNNVTLG-------NARMGYYETV 1120
Cdd:pfam02538  300 LRPIEVIAPEGSLLNPSPPAAVVGGNVETSQRIVDVVLGALAqalperVPAASQGTMNNLTFGgvdprggGRFFGYYETI 379
                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 23346557   1121 AGGAGAGPGWHGRSGVHSHMTNTRITDPEILESRYPVILRRFELrpgsggrgrfrggDG-------------VVRELVFR 1187
Cdd:pfam02538  380 GGGSGARPGGDGLDGVHVHMTNTRNTPVEVLERRYPVLVERYEL-------------RPdsggagryrggdgVVREIEFL 446
                          490       500       510       520       530       540       550
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 23346557   1188 E-EALLSVLTERRAFQPYGLHGGEPGTRGLNLLIRKdgrtvnlggKTSVTVYPGDAFCLHTPGGGGYGDP 1256
Cdd:pfam02538  447 ApDATVSILSERRVFPPWGLAGGEPGAPGRVNLGGK---------ATDVELKPGDRLRIETPGGGGYGDP 507
HyuA COG0145
N-methylhydantoinase A/oxoprolinase/acetone carboxylase, beta subunit [Amino acid transport ...
10-725 0e+00

N-methylhydantoinase A/oxoprolinase/acetone carboxylase, beta subunit [Amino acid transport and metabolism, Secondary metabolites biosynthesis, transport and catabolism];


Pssm-ID: 439915 [Multi-domain]  Cd Length: 678  Bit Score: 646.38  E-value: 0e+00
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 23346557   10 FAIDRGGTFTDVFAQCPGGHVRVLKLLSeDPANYADAPTEGIRRILEQErgvllprgrPLDTSHIASIRMGTTVATNALL 89
Cdd:COG0145    1 VGVDVGGTFTDVVAVDEDGRLRTHKVLS-TPEDPSDGVLEGIRELLEDA---------GIPLAEIDLVVHGTTVATNALL 70
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 23346557   90 ERQGERVALLVTRGFRDLLHIGTQARPDLFDLAVPMPEvlyeevvevdervLLYRGEPgagspVKGCTGDLL---EIQQP 166
Cdd:COG0145   71 ERKGARTGLITTRGFRDVLEIGRQNRPDLYDLFIEKPE-------------PLVPRRL-----RFEVRERIDadgEVLTP 132
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 23346557  167 VDLAALRGKLEGLLTRGIHSLAVVLMHSYTWAQHEQQVGTLARE-LGFTHVSLSSEVMPMVRIVPRGHTACADAYLTPTI 245
Cdd:COG0145  133 LDEAEVRAAARELRAAGVEAVAVCFLHSYRNPAHERRAAEILREeLPDVPVSLSSEVSPEIREYERTSTTVVNAYLSPIL 212
                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 23346557  246 QRYVQGFRRGFQGQLKNVQVLFMRSDGGLAPMDAFS--GSRAVLSGPAGGVVGySTTTYQLEGGQPVIGFDMGGTSTDVS 323
Cdd:COG0145  213 RRYLDRLEARLRERGFGGPLLIMQSNGGLASAEAAArrPVRTILSGPAGGVVG-AAALARAAGFDNVITFDMGGTSTDVS 291
                        330       340       350       360       370       380       390       400
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 23346557  324 RYA-GEFEHVFEASTAGVTLQAPQLDINTVAAGGGSRLFF-RSGLFVVGPESAGAHPGPACYRKGGP-VTVTDANLVLGR 400
Cdd:COG0145  292 LIEdGEPERTTETEVAGYPVRVPMVDIHTVGAGGGSIAWVdAGGRLRVGPESAGADPGPACYGRGGTePTVTDANLVLGR 371
                        410       420       430       440       450       460       470       480
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 23346557  401 LLPASFPcifgpGEDQPLSPEASRKALEAVAMEVNsflasgpcpasqLSLEEVAMGFVRVANEAMCRPIRALTQARGHDP 480
Cdd:COG0145  372 LDPDNFL-----GGRMPLDVEAARAAIEKLADPLG------------LSVEEAAEGILRIANENMANAIRKVSVERGYDP 434
                        490       500       510       520       530       540       550       560
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 23346557  481 SAHVLACFGGAGGQHACAIARALGMDTVHIHRHSGLLSALGLALADVVHEAQEPCSLSYTPETFAQLDQRLSRLEEQCVD 560
Cdd:COG0145  435 RDFTLVAFGGAGPLHACALAEELGIPRVIVPPAAGVLSALGMLLADIRHDYVRSVEAPLDDADLAELNAAFAELEAEARA 514
                        570       580       590       600       610       620       630       640
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 23346557  561 ALQAQGFSRSQISTESFLHLRYQGTDCALMVSANQHPATTCSprAGDFGAAFVERYMREFGFIIPERSVVVDDVRVRGTG 640
Cdd:COG0145  515 ELAAEGVAAEDIRVERSADMRYAGQGHELTVPLPAGRLDAAD--LAALRAAFHAAHERRYGFALPDAPVEIVNLRVEAIG 592
                        650       660       670       680       690       700       710       720
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 23346557  641 RSG-LQLEETSKIQSGPPHVEKVTQCYFEGGYQETPVYLLGELGYGHQLQGPCLIIDNNSTILVEPGCQAEVIETGDIRI 719
Cdd:COG0145  593 PVPkPELPRLPPGGDAAPAPKGTRPVYFDGGWVDTPVYDREALPPGDRIAGPAIIEEPDTTTVVPPGWRATVDAYGNLIL 672

                 ....*.
gi 23346557  720 SVGAEA 725
Cdd:COG0145  673 TRAAAA 678
 
Name Accession Description Interval E-value
PLN02666 PLN02666
5-oxoprolinase
1-1258 0e+00

5-oxoprolinase


Pssm-ID: 215358 [Multi-domain]  Cd Length: 1275  Bit Score: 1904.83  E-value: 0e+00
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 23346557     1 MGSPEER-FHFAIDRGGTFTDVFAQCPGG-HVRVLKLLSEDPANYADAPTEGIRRILEQERGVLLPRGRPLDTSHIASIR 78
Cdd:PLN02666    2 MGSRGSRkFRFCIDRGGTFTDVYAEVPGGsDFRVLKLLSVDPANYDDAPREGIRRILEEVTGKKIPRSAKIPTERIEWIR 81
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 23346557    79 MGTTVATNALLERQGERVALLVTRGFRDLLHIGTQARPDLFDLAVPMPEVLYEEVVEVDERVLLYRGEPGA---GSPVKG 155
Cdd:PLN02666   82 MGTTVATNALLERKGERIALCVTKGFKDLLQIGNQARPNIFDLTVSKPSNLYEEVVEVDERVVLALEEDGDdagGSVVKG 161
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 23346557   156 CTGDLLEIQQPVDLAALRGKLEGLLTRGIHSLAVVLMHSYTWAQHEQQVGTLARELGFTHVSLSSEVMPMVRIVPRGHTA 235
Cdd:PLN02666  162 VTGELVEVVKPLDEEALRPLLQGLLDKGIRSLAVVLMHSYTYPAHERAVGKLARSMGFKQVSLSSALVPMVRAVPRGHTA 241
                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 23346557   236 CADAYLTPTIQRYVQGFRRGFQGQLKNVQVLFMRSDGGLAPMDAFSGSRAVLSGPAGGVVGYSTTTYQLEGGQPVIGFDM 315
Cdd:PLN02666  242 SVDAYLTPVIKEYLSGFLSGFDDGLGDVNVLFMQSDGGLTPESRFSGHKAILSGPAGGVVGYAQTTFGLETEKPVIGFDM 321
                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 23346557   316 GGTSTDVSRYAGEFEHVFEASTAGVTLQAPQLDINTVAAGGGSRLFFRSGLFVVGPESAGAHPGPACYRKGGPVTVTDAN 395
Cdd:PLN02666  322 GGTSTDVSRYDGSYEQVLETQTAGVIIQAPQLDINTVAAGGGSKLKFQFGAFRVGPESVGAHPGPVCYRKGGELAVTDAN 401
                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 23346557   396 LVLGRLLPASFPCIFGPGEDQPLSPEASRKALEAVAMEVNSFLASGPCPASQLSLEEVAMGFVRVANEAMCRPIRALTQA 475
Cdd:PLN02666  402 LVLGRVIPDYFPSIFGPNEDEPLDLEATRAAFEALAAQINSYRKSQDPSAKDMSVEEVALGFVRVANEAMCRPIRQLTEM 481
                         490       500       510       520       530       540       550       560
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 23346557   476 RGHDPSAHVLACFGGAGGQHACAIARALGMDTVHIHRHSGLLSALGLALADVVHEAQEPCSLSYTPETFAQLDQRLSRLE 555
Cdd:PLN02666  482 KGYETANHALACFGGAGPQHACAIARALGMSEVFVHRYCGILSAYGMGLADVVAEAQEPYAAVYGPESLAEASRREDALA 561
                         570       580       590       600       610       620       630       640
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 23346557   556 EQCVDALQAQGFSRSQISTESFLHLRYQGTDCALMVSanQHPATTCSPraGDFGAAFVERYMREFGFIIPERSVVVDDVR 635
Cdd:PLN02666  562 EKVRQKLQEQGFREDNITTETYLNLRYEGTDTAIMVA--EPENGDGSD--GDYAAAFVKLFRREYGFKLQNRDILIDDVR 637
                         650       660       670       680       690       700       710       720
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 23346557   636 VRGTGRSG-LQLEETSKIQSGPPHVEKVTQCYFEGGYQETPVYLLGELGYGHQLQGPCLIIDNNSTILVEPGCQAEVIET 714
Cdd:PLN02666  638 VRGIGVTNiLKPLPLDAASGGLPEPERTTKVYFENGWHDTPVYKLENLGPGHEIPGPAIIMNGNSTVVVEPGCKAIVTKY 717
                         730       740       750       760       770       780       790       800
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 23346557   715 GDIRISVG-------AEAPSMIDTKLDPIQLSIFSHRFMSIAEQMGRILQRTAISTNIKERLDFSCALFGPDGGLVSNAP 787
Cdd:PLN02666  718 GNIKIEVEnsaeqsaEETVKAAEKKADVVQLSIFNHRFMGIAEQMGRTLQRTSISTNIKERLDFSCALFGPDGGLVANAP 797
                         810       820       830       840       850       860       870       880
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 23346557   788 HIPVHLGAMQETVQFQIQHLGADLHPGDVLLSNHPSAGGSHLPDLTVITPVFWPGqsRPVFYVASRGHHADIGGITPGSM 867
Cdd:PLN02666  798 HVPVHLGAMSSTVRWQLEYWGENLNEGDVLVTNHPQAGGSHLPDITVITPVFRDG--KIVFFVASRGHHADIGGITPGSM 875
                         890       900       910       920       930       940       950       960
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 23346557   868 PPHSTTLQQEGAVFLSFKLVQGGVFQEEAVTEALQAPGKISGC---SGTRNLHDNLSDLRAQVAANQKGIQLVGELIGQY 944
Cdd:PLN02666  876 PPFSKTIWEEGAAIKAFKLVEGGVFQEEGITKLLQAPGSDETApkiPGTRRLQDNLSDLRAQVAANQRGISLIKELIDEY 955
                         970       980       990      1000      1010      1020      1030      1040
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 23346557   945 GLDVVQAYMGHIQANAELAVRDMLRAFGT--SRQARGLPLEVS----AKDHMDDGSPICLHVQINLNQGSAVFDFSGSGS 1018
Cdd:PLN02666  956 GLGTVQAYMGHVQANAELAVREMLKSVAArvSSESPTFGDGSSvtleAEDYMDDGSPIHLTLTIDRRKGSAVFDFEGTSP 1035
                        1050      1060      1070      1080      1090      1100      1110      1120
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 23346557  1019 EVFGNLNAPRAITLSALIYCLRCLVGRDIPLNQGCLAPVQVIIPKGSILDPSPEAAVVGGNVLTSQRVVDVILGAFGACA 1098
Cdd:PLN02666 1036 EVYGNWNAPPAVTAAAVIYCLRCLVDVDIPLNQGCLAPVTIRIPPGSFLSPSDKAAVVGGNVLTSQRVTDVVLTAFQACA 1115
                        1130      1140      1150      1160      1170      1180      1190      1200
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 23346557  1099 ASQGCMNNVTLGNARMGYYETVAGGAGAGPGWHGRSGVHSHMTNTRITDPEILESRYPVILRRFELRPGSGGRGRFRGGD 1178
Cdd:PLN02666 1116 CSQGCMNNLTFGDDTFGYYETIAGGAGAGPTWDGTSGVQCHMTNTRITDPEILERRYPVLLHRFGLREGSGGDGLHRGGD 1195
                        1210      1220      1230      1240      1250      1260      1270      1280
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 23346557  1179 GVVRELVFREEALLSVLTERRAFQPYGLHGGEPGTRGLNLLIRKDGRTVNLGGKTSVTVYPGDAFCLHTPGGGGYGDPED 1258
Cdd:PLN02666 1196 GVVREIEFRRPVTVSILSERRVHAPRGLAGGGDGARGANLLIRKDGRRVNLGGKNTVHVEAGERLRILTPGGGGYGSKPS 1275
Hydantoinase_B pfam02538
Hydantoinase B/oxoprolinase; This family includes N-methylhydaintoinase B which converts ...
735-1256 0e+00

Hydantoinase B/oxoprolinase; This family includes N-methylhydaintoinase B which converts hydantoin to N-carbamyl-amino acids, and 5-oxoprolinase EC:3.5.2.9 which catalyzes the formation of L-glutamate from 5-oxo-L-proline. These enzymes are part of the oxoprolinase family and are related to pfam01968.


Pssm-ID: 460583  Cd Length: 507  Bit Score: 687.28  E-value: 0e+00
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 23346557    735 PIQLSIFSHRFMSIAEQMGRILQRTAISTNIKERLDFSCALFGPDGGLVSNAPHIPVHLGAMQETVQFQIQHLGaDLHPG 814
Cdd:pfam02538    1 PITLEVFRNRLMSIAEEMGRTLQRTAFSPNIKERLDFSCAIFDADGRLVAQAPHIPVHLGSMSFAVKAVIEYGG-DLRPG 79
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 23346557    815 DVLLSNHPSAGGSHLPDLTVITPVFWPGqsRPVFYVASRGHHADIGGITPGSMPPHSTTLQQEGAVFLSFKLVQGGVfQE 894
Cdd:pfam02538   80 DVFITNDPYAGGTHLPDITVITPVFHDG--ELVFFVASRGHHADIGGIVPGSMPPDATEIYQEGLRIPPVKLVRRGV-LN 156
                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 23346557    895 EAVTEALqapgkisgCSGTRNLHDNLSDLRAQVAANQKGIQLVGELIGQYGLDVVQAYMGHIQANAELAVRDMLRAfgts 974
Cdd:pfam02538  157 EDVLRLL--------LANSRTPEDNLGDLKAQIAANRVGERRLLELIDEYGLDTVLAAMDEIQDYAERAVRAAIAA---- 224
                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 23346557    975 rqargLPL-EVSAKDHMDDGSPICLHVQINLNQGSAVFDFSGSGSEVFGNLNAPRAITLSALIYCLRCLVGRDIPLNQGC 1053
Cdd:pfam02538  225 -----LPDgTYEAEDYLDDGVPIPIRVTVTIDGDEATVDFTGTSPQVPGNINAPLAVTHSAVIYALRCLVDPDIPLNAGC 299
                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 23346557   1054 LAPVQVIIPKGSILDPSPEAAVVGGNVLTSQRVVDVILGAFG------ACAASQGCMNNVTLG-------NARMGYYETV 1120
Cdd:pfam02538  300 LRPIEVIAPEGSLLNPSPPAAVVGGNVETSQRIVDVVLGALAqalperVPAASQGTMNNLTFGgvdprggGRFFGYYETI 379
                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 23346557   1121 AGGAGAGPGWHGRSGVHSHMTNTRITDPEILESRYPVILRRFELrpgsggrgrfrggDG-------------VVRELVFR 1187
Cdd:pfam02538  380 GGGSGARPGGDGLDGVHVHMTNTRNTPVEVLERRYPVLVERYEL-------------RPdsggagryrggdgVVREIEFL 446
                          490       500       510       520       530       540       550
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 23346557   1188 E-EALLSVLTERRAFQPYGLHGGEPGTRGLNLLIRKdgrtvnlggKTSVTVYPGDAFCLHTPGGGGYGDP 1256
Cdd:pfam02538  447 ApDATVSILSERRVFPPWGLAGGEPGAPGRVNLGGK---------ATDVELKPGDRLRIETPGGGGYGDP 507
HyuA COG0145
N-methylhydantoinase A/oxoprolinase/acetone carboxylase, beta subunit [Amino acid transport ...
10-725 0e+00

N-methylhydantoinase A/oxoprolinase/acetone carboxylase, beta subunit [Amino acid transport and metabolism, Secondary metabolites biosynthesis, transport and catabolism];


Pssm-ID: 439915 [Multi-domain]  Cd Length: 678  Bit Score: 646.38  E-value: 0e+00
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 23346557   10 FAIDRGGTFTDVFAQCPGGHVRVLKLLSeDPANYADAPTEGIRRILEQErgvllprgrPLDTSHIASIRMGTTVATNALL 89
Cdd:COG0145    1 VGVDVGGTFTDVVAVDEDGRLRTHKVLS-TPEDPSDGVLEGIRELLEDA---------GIPLAEIDLVVHGTTVATNALL 70
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 23346557   90 ERQGERVALLVTRGFRDLLHIGTQARPDLFDLAVPMPEvlyeevvevdervLLYRGEPgagspVKGCTGDLL---EIQQP 166
Cdd:COG0145   71 ERKGARTGLITTRGFRDVLEIGRQNRPDLYDLFIEKPE-------------PLVPRRL-----RFEVRERIDadgEVLTP 132
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 23346557  167 VDLAALRGKLEGLLTRGIHSLAVVLMHSYTWAQHEQQVGTLARE-LGFTHVSLSSEVMPMVRIVPRGHTACADAYLTPTI 245
Cdd:COG0145  133 LDEAEVRAAARELRAAGVEAVAVCFLHSYRNPAHERRAAEILREeLPDVPVSLSSEVSPEIREYERTSTTVVNAYLSPIL 212
                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 23346557  246 QRYVQGFRRGFQGQLKNVQVLFMRSDGGLAPMDAFS--GSRAVLSGPAGGVVGySTTTYQLEGGQPVIGFDMGGTSTDVS 323
Cdd:COG0145  213 RRYLDRLEARLRERGFGGPLLIMQSNGGLASAEAAArrPVRTILSGPAGGVVG-AAALARAAGFDNVITFDMGGTSTDVS 291
                        330       340       350       360       370       380       390       400
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 23346557  324 RYA-GEFEHVFEASTAGVTLQAPQLDINTVAAGGGSRLFF-RSGLFVVGPESAGAHPGPACYRKGGP-VTVTDANLVLGR 400
Cdd:COG0145  292 LIEdGEPERTTETEVAGYPVRVPMVDIHTVGAGGGSIAWVdAGGRLRVGPESAGADPGPACYGRGGTePTVTDANLVLGR 371
                        410       420       430       440       450       460       470       480
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 23346557  401 LLPASFPcifgpGEDQPLSPEASRKALEAVAMEVNsflasgpcpasqLSLEEVAMGFVRVANEAMCRPIRALTQARGHDP 480
Cdd:COG0145  372 LDPDNFL-----GGRMPLDVEAARAAIEKLADPLG------------LSVEEAAEGILRIANENMANAIRKVSVERGYDP 434
                        490       500       510       520       530       540       550       560
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 23346557  481 SAHVLACFGGAGGQHACAIARALGMDTVHIHRHSGLLSALGLALADVVHEAQEPCSLSYTPETFAQLDQRLSRLEEQCVD 560
Cdd:COG0145  435 RDFTLVAFGGAGPLHACALAEELGIPRVIVPPAAGVLSALGMLLADIRHDYVRSVEAPLDDADLAELNAAFAELEAEARA 514
                        570       580       590       600       610       620       630       640
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 23346557  561 ALQAQGFSRSQISTESFLHLRYQGTDCALMVSANQHPATTCSprAGDFGAAFVERYMREFGFIIPERSVVVDDVRVRGTG 640
Cdd:COG0145  515 ELAAEGVAAEDIRVERSADMRYAGQGHELTVPLPAGRLDAAD--LAALRAAFHAAHERRYGFALPDAPVEIVNLRVEAIG 592
                        650       660       670       680       690       700       710       720
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 23346557  641 RSG-LQLEETSKIQSGPPHVEKVTQCYFEGGYQETPVYLLGELGYGHQLQGPCLIIDNNSTILVEPGCQAEVIETGDIRI 719
Cdd:COG0145  593 PVPkPELPRLPPGGDAAPAPKGTRPVYFDGGWVDTPVYDREALPPGDRIAGPAIIEEPDTTTVVPPGWRATVDAYGNLIL 672

                 ....*.
gi 23346557  720 SVGAEA 725
Cdd:COG0145  673 TRAAAA 678
HyuB COG0146
N-methylhydantoinase B/oxoprolinase/acetone carboxylase, alpha subunit [Amino acid transport ...
729-1258 0e+00

N-methylhydantoinase B/oxoprolinase/acetone carboxylase, alpha subunit [Amino acid transport and metabolism, Secondary metabolites biosynthesis, transport and catabolism];


Pssm-ID: 439916  Cd Length: 563  Bit Score: 600.59  E-value: 0e+00
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 23346557  729 IDTKLDPIQLSIFSHRFMSIAEQMGRILQRTAISTNIKERLDFSCALFGPDGGLVSNAPHIPVHLGAMQETVQFQIQHLG 808
Cdd:COG0146    1 LGTTVDPVTLEVIRNRLIAIAEEMGETLQRTAFSPNIKERLDFSCALFDADGRLVAQAPGIPVHLGSMPEAVKAVIERFG 80
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 23346557  809 A-DLHPGDVLLSNHPSAGGSHLPDLTVITPVFWPGqsRPVFYVASRGHHADIGGITPGSMPPHSTTLQQEGAVFLSFKLV 887
Cdd:COG0146   81 NdGIRPGDVFITNDPYLGGTHLPDITVVTPVFHDG--ELVGFVASRAHHADIGGIVPGSMPPDATEIFQEGLRIPPVKLV 158
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 23346557  888 QGGVFQEEAVTEALqapgkisgcSGTRNLHDNLSDLRAQVAANQKGIQLVGELIGQYGLDVVQAYMGHIQANAELAVRDM 967
Cdd:COG0146  159 EAGELNEDVLRLIL---------ANVRTPDQNLGDLRAQIAANRVGERRLLELVERYGLDTVEAAMDELLDYAERAVRAA 229
                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 23346557  968 LRAfgtsrqargLPL-EVSAKDHMDDGS----PICLHVQINLNQGSAVFDFSGSGSEVFGNLNAPRAITLSALIYCLRCL 1042
Cdd:COG0146  230 IAA---------LPDgTYRAEDFLDDDGvgdePIKIKVTVTVKGDRITVDFTGTSPQVPGNINAPLAVTRAAVLYALRCL 300
                        330       340       350       360       370       380       390       400
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 23346557 1043 VGRDIPLNQGCLAPVQVIIPKGSILDPSPEAAVVGGNVLTSQRVVDVILGAFG------ACAASQGCMNNVTLGNAR--- 1113
Cdd:COG0146  301 LDPDIPLNAGCLRPIEVIAPEGSILNPRYPAAVVAGNVETSQRVVDAVFGALAqalperVPAASQGTMNNLTFGGVDprg 380
                        410       420       430       440       450       460       470       480
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 23346557 1114 --MGYYETVAGGAGAGPGWHGRSGVHSHMTNTRITDPEILESRYPVILRRFELrpgsggrgrfrggDG------------ 1179
Cdd:COG0146  381 epFVYYETIGGGSGARPGGDGLDAVHTHMTNTRNTPVEVLEARYPVLVERYEL-------------RPdsggagkyrggl 447
                        490       500       510       520       530       540       550       560
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 23346557 1180 -VVRELVFRE-EALLSVLTERRAFQPYGLHGGEPGTRGLNLLIRKDGRTVNLGGKTSVTVYPGDAFCLHTPGGGGYGDPE 1257
Cdd:COG0146  448 gVVREIRFLEpEMTVSLLGDRRRFPPWGLAGGGPGAPGRNVLVRGDGDEEELGGKATVPLQPGDVVVIETPGGGGYGDPL 527

                 .
gi 23346557 1258 D 1258
Cdd:COG0146  528 E 528
Hydantoinase_A pfam01968
Hydantoinase/oxoprolinase; This family includes the enzymes hydantoinase and oxoprolinase EC:3. ...
231-513 5.76e-104

Hydantoinase/oxoprolinase; This family includes the enzymes hydantoinase and oxoprolinase EC:3.5.2.9. Both reactions involve the hydrolysis of 5-membered rings via hydrolysis of their internal imide bonds.


Pssm-ID: 396517 [Multi-domain]  Cd Length: 288  Bit Score: 330.79  E-value: 5.76e-104
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 23346557    231 RGHTACADAYLTPTIQRYVQGFRRGFQGQLKNVQVLFMRSDGGLAPMDAFSG--SRAVLSGPAGGVVGYSTTTyQLEGGQ 308
Cdd:pfam01968    1 RTVTAVVNAYLAPIMREYLEGVEDSLEKVGSKAPVYVMQSDGGLVSIDEARKrpVETILSGPAAGVVGAAYTG-KLLGNK 79
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 23346557    309 PVIGFDMGGTSTDVSRYA-GEFEHVFEASTAGVTLQAPQLDINTVAAGGGSRL-FFRSGLFVVGPESAGAHPGPACYRKG 386
Cdd:pfam01968   80 NLIGFDMGGTSTDISPIIdGEPEITTETEVAGYPTRLPRLDINTVGAGGGSILvSFLGGKVRVGPESAGADPGPACYRKG 159
                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 23346557    387 G-PVTVTDANLVLGRLLPASFPCIfgpgeDQPLSPEASRKALEAVAMEVNsflasgpcpasqLSLEEVAMGFVRVANEAM 465
Cdd:pfam01968  160 GtFPTVTDANLVLGRLNPEDFLGG-----DGKLDVEAARRAFEKLADPLN------------LGVEEVAEGIIRIANETM 222
                          250       260       270       280
                   ....*....|....*....|....*....|....*....|....*...
gi 23346557    466 CRPIRALTQARGHDPSAHVLACFGGAGGQHACAIARALGMDTVHIHRH 513
Cdd:pfam01968  223 ARAVRLVTVERGYDPSEFVLVVFGGAGPQHAPALAEELGIKKVIVPPY 270
Hydant_A_N pfam05378
Hydantoinase/oxoprolinase N-terminal region; This family is found at the N-terminus of the ...
9-212 2.44e-58

Hydantoinase/oxoprolinase N-terminal region; This family is found at the N-terminus of the pfam01968 family.


Pssm-ID: 398834 [Multi-domain]  Cd Length: 176  Bit Score: 198.67  E-value: 2.44e-58
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 23346557      9 HFAIDRGGTFTDVFAQCPG-GHVRVLKLLSEDpanyaDAPTEGIRRILEQERGVLLPRgrpldTSHIASIRMGTTVATNA 87
Cdd:pfam05378    1 RIGIDVGGTFTDAVALDEGdGEVAVIKVLTTP-----DDPVEGIREALEELLGELGPR-----TGKVDTVRHGTTVATNA 70
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 23346557     88 LLERQGERVALLVTRGFRDLLHIGTQARPDLFDLAVPmpevlyeevvevderVLLY--RGEPGAGSPVKGctgdllEIQQ 165
Cdd:pfam05378   71 LLERKGARVGLITTKGFRDLLEIGRQNRPDLFDLYKP---------------LVLYelVVEVDERVDADG------EVLK 129
                          170       180       190       200
                   ....*....|....*....|....*....|....*....|....*..
gi 23346557    166 PVDLAALRGKLEGLLTRGIHSLAVVLMHSYTWAQHEQQVGTLARELG 212
Cdd:pfam05378  130 PLDEEEVREALKALKDAGVEAIAVVLLHSYLNPEHELRVAEIAREEG 176
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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