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Conserved domains on  [gi|24642153|ref|NP_727845|]
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abnormal chemosensory jump 6, isoform E [Drosophila melanogaster]

Protein Classification

POU family transcription factor( domain architecture ID 11265437)

POU (Pit-Oct-Unc) family transcription factor binds specific DNA sequences to direct gene expression programs, playing a role in orchestrating embryonic development and directing cellular fate

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
POU smart00352
Found in Pit-Oct-Unc transcription factors;
203-280 1.61e-46

Found in Pit-Oct-Unc transcription factors;


:

Pssm-ID: 197673  Cd Length: 75  Bit Score: 153.36  E-value: 1.61e-46
                           10        20        30        40        50        60        70
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 24642153    203 DTDTDPRELEAFAERFKQRRIKLGVTQADVGKALANLKLPgvgALSQSTICRFESLTLSHNNMIALKPILQAWLEEAE 280
Cdd:smart00352   1 DDDTDPRELEAFAKQFKQRRIKLGFTQADVGLALGALYGP---AFSQTTICRFEALQLSFKNMCKLKPLLQKWLEEAE 75
Homeodomain pfam00046
Homeodomain;
301-356 1.56e-18

Homeodomain;


:

Pssm-ID: 459649 [Multi-domain]  Cd Length: 57  Bit Score: 78.31  E-value: 1.56e-18
                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|....*.
gi 24642153   301 KKRTSIAAPEKRSLEAYFAVQPRPSGEKIAAIAEKLDLKKNVVRVWFCNQRQKQKR 356
Cdd:pfam00046   2 RKRTTFTPEQLEELEKEFQENPYPSAEEREELAAQLGLTERQVKVWFQNRRAKWKR 57
 
Name Accession Description Interval E-value
POU smart00352
Found in Pit-Oct-Unc transcription factors;
203-280 1.61e-46

Found in Pit-Oct-Unc transcription factors;


Pssm-ID: 197673  Cd Length: 75  Bit Score: 153.36  E-value: 1.61e-46
                           10        20        30        40        50        60        70
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 24642153    203 DTDTDPRELEAFAERFKQRRIKLGVTQADVGKALANLKLPgvgALSQSTICRFESLTLSHNNMIALKPILQAWLEEAE 280
Cdd:smart00352   1 DDDTDPRELEAFAKQFKQRRIKLGFTQADVGLALGALYGP---AFSQTTICRFEALQLSFKNMCKLKPLLQKWLEEAE 75
Pou pfam00157
Pou domain - N-terminal to homeobox domain;
206-280 1.25e-34

Pou domain - N-terminal to homeobox domain;


Pssm-ID: 459692  Cd Length: 72  Bit Score: 122.00  E-value: 1.25e-34
                          10        20        30        40        50        60        70
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 24642153   206 TDPRELEAFAERFKQRRIKLGVTQADVGKALANLKLPGVgalSQSTICRFESLTLSHNNMIALKPILQAWLEEAE 280
Cdd:pfam00157   1 LNLEELEEFAKEFKQRRIKLGYTQADVGSALGALYGPVF---SQSTICRFEKLDLSLKNMCKLKPLLEKWLEEAE 72
Homeodomain pfam00046
Homeodomain;
301-356 1.56e-18

Homeodomain;


Pssm-ID: 459649 [Multi-domain]  Cd Length: 57  Bit Score: 78.31  E-value: 1.56e-18
                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|....*.
gi 24642153   301 KKRTSIAAPEKRSLEAYFAVQPRPSGEKIAAIAEKLDLKKNVVRVWFCNQRQKQKR 356
Cdd:pfam00046   2 RKRTTFTPEQLEELEKEFQENPYPSAEEREELAAQLGLTERQVKVWFQNRRAKWKR 57
HOX smart00389
Homeodomain; DNA-binding factors that are involved in the transcriptional regulation of key ...
 299-355 1.49e-14

Homeodomain; DNA-binding factors that are involved in the transcriptional regulation of key developmental processes


Pssm-ID: 197696 [Multi-domain]  Cd Length: 57  Bit Score: 67.28  E-value: 1.49e-14
                           10        20        30        40        50
                   ....*....|....*....|....*....|....*....|....*....|....*..
gi 24642153    299 GEKKRTSIAAPEKRSLEAYFAVQPRPSGEKIAAIAEKLDLKKNVVRVWFCNQRQKQK 355
Cdd:smart00389   1 KRRKRTSFTPEQLEELEKEFQKNPYPSREEREELAKKLGLSERQVKVWFQNRRAKWK 57
homeodomain cd00086
Homeodomain; DNA binding domains involved in the transcriptional regulation of key eukaryotic ...
 301-356 6.12e-14

Homeodomain; DNA binding domains involved in the transcriptional regulation of key eukaryotic developmental processes; may bind to DNA as monomers or as homo- and/or heterodimers, in a sequence-specific manner.


Pssm-ID: 238039 [Multi-domain]  Cd Length: 59  Bit Score: 65.73  E-value: 6.12e-14
                        10        20        30        40        50
                ....*....|....*....|....*....|....*....|....*....|....*.
gi 24642153 301 KKRTSIAAPEKRSLEAYFAVQPRPSGEKIAAIAEKLDLKKNVVRVWFCNQRQKQKR 356
Cdd:cd00086   2 RKRTRFTPEQLEELEKEFEKNPYPSREEREELAKELGLTERQVKIWFQNRRAKLKR 57
COG5576 COG5576
Homeodomain-containing transcription factor [Transcription];
273-357 4.93e-05

Homeodomain-containing transcription factor [Transcription];


Pssm-ID: 227863 [Multi-domain]  Cd Length: 156  Bit Score: 43.19  E-value: 4.93e-05
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24642153 273 QAWLEEAEAQAKN--KRRDPDaPSVLPAGEKKRTSIAapEKRSLEAYFAVQPRPSGEKIAAIAEKLDLKKNVVRVWFCNQ 350
Cdd:COG5576  26 TKNKREVEAADSEmkLERKQD-GSSPPKSKRRRTTDE--QLMVLEREFEINPYPSSITRIKLSLLLNMPPKSVQIWFQNK 102


                ....*..
gi 24642153 351 RQKQKRI 357
Cdd:COG5576 103 RAKEKKK 109
 
Name Accession Description Interval E-value
POU smart00352
Found in Pit-Oct-Unc transcription factors;
203-280 1.61e-46

Found in Pit-Oct-Unc transcription factors;


Pssm-ID: 197673  Cd Length: 75  Bit Score: 153.36  E-value: 1.61e-46
                           10        20        30        40        50        60        70
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 24642153    203 DTDTDPRELEAFAERFKQRRIKLGVTQADVGKALANLKLPgvgALSQSTICRFESLTLSHNNMIALKPILQAWLEEAE 280
Cdd:smart00352   1 DDDTDPRELEAFAKQFKQRRIKLGFTQADVGLALGALYGP---AFSQTTICRFEALQLSFKNMCKLKPLLQKWLEEAE 75
Pou pfam00157
Pou domain - N-terminal to homeobox domain;
206-280 1.25e-34

Pou domain - N-terminal to homeobox domain;


Pssm-ID: 459692  Cd Length: 72  Bit Score: 122.00  E-value: 1.25e-34
                          10        20        30        40        50        60        70
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 24642153   206 TDPRELEAFAERFKQRRIKLGVTQADVGKALANLKLPGVgalSQSTICRFESLTLSHNNMIALKPILQAWLEEAE 280
Cdd:pfam00157   1 LNLEELEEFAKEFKQRRIKLGYTQADVGSALGALYGPVF---SQSTICRFEKLDLSLKNMCKLKPLLEKWLEEAE 72
Homeodomain pfam00046
Homeodomain;
301-356 1.56e-18

Homeodomain;


Pssm-ID: 459649 [Multi-domain]  Cd Length: 57  Bit Score: 78.31  E-value: 1.56e-18
                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|....*.
gi 24642153   301 KKRTSIAAPEKRSLEAYFAVQPRPSGEKIAAIAEKLDLKKNVVRVWFCNQRQKQKR 356
Cdd:pfam00046   2 RKRTTFTPEQLEELEKEFQENPYPSAEEREELAAQLGLTERQVKVWFQNRRAKWKR 57
HOX smart00389
Homeodomain; DNA-binding factors that are involved in the transcriptional regulation of key ...
 299-355 1.49e-14

Homeodomain; DNA-binding factors that are involved in the transcriptional regulation of key developmental processes


Pssm-ID: 197696 [Multi-domain]  Cd Length: 57  Bit Score: 67.28  E-value: 1.49e-14
                           10        20        30        40        50
                   ....*....|....*....|....*....|....*....|....*....|....*..
gi 24642153    299 GEKKRTSIAAPEKRSLEAYFAVQPRPSGEKIAAIAEKLDLKKNVVRVWFCNQRQKQK 355
Cdd:smart00389   1 KRRKRTSFTPEQLEELEKEFQKNPYPSREEREELAKKLGLSERQVKVWFQNRRAKWK 57
homeodomain cd00086
Homeodomain; DNA binding domains involved in the transcriptional regulation of key eukaryotic ...
 301-356 6.12e-14

Homeodomain; DNA binding domains involved in the transcriptional regulation of key eukaryotic developmental processes; may bind to DNA as monomers or as homo- and/or heterodimers, in a sequence-specific manner.


Pssm-ID: 238039 [Multi-domain]  Cd Length: 59  Bit Score: 65.73  E-value: 6.12e-14
                        10        20        30        40        50
                ....*....|....*....|....*....|....*....|....*....|....*.
gi 24642153 301 KKRTSIAAPEKRSLEAYFAVQPRPSGEKIAAIAEKLDLKKNVVRVWFCNQRQKQKR 356
Cdd:cd00086   2 RKRTRFTPEQLEELEKEFEKNPYPSREEREELAKELGLTERQVKIWFQNRRAKLKR 57
COG5576 COG5576
Homeodomain-containing transcription factor [Transcription];
273-357 4.93e-05

Homeodomain-containing transcription factor [Transcription];


Pssm-ID: 227863 [Multi-domain]  Cd Length: 156  Bit Score: 43.19  E-value: 4.93e-05
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24642153 273 QAWLEEAEAQAKN--KRRDPDaPSVLPAGEKKRTSIAapEKRSLEAYFAVQPRPSGEKIAAIAEKLDLKKNVVRVWFCNQ 350
Cdd:COG5576  26 TKNKREVEAADSEmkLERKQD-GSSPPKSKRRRTTDE--QLMVLEREFEINPYPSSITRIKLSLLLNMPPKSVQIWFQNK 102


                ....*..
gi 24642153 351 RQKQKRI 357
Cdd:COG5576 103 RAKEKKK 109
HTH_31 pfam13560
Helix-turn-helix domain; This domain is a helix-turn-helix domain that probably binds to DNA.
 213-257 7.94e-03

Helix-turn-helix domain; This domain is a helix-turn-helix domain that probably binds to DNA.


Pssm-ID: 433309 [Multi-domain]  Cd Length: 64  Bit Score: 34.43  E-value: 7.94e-03
                          10        20        30        40
                  ....*....|....*....|....*....|....*....|....*
gi 24642153   213 AFAERFKQRRIKLGVTQADVGKALanlklpGVgalSQSTICRFES 257
Cdd:pfam13560   1 ELGARLRRLRERAGLSQEALARRL------GV---SRSTLSRLET 36
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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