NCBI Home Page NCBI Site Search page NCBI Guide that lists and describes the NCBI resources
Conserved domains on  [gi|30425310|ref|NP_780742|]
View 

scavenger receptor family member expressed on T cells 2 isoform 3 precursor [Mus musculus]

Protein Classification

scavenger receptor cysteine-rich domain-containing protein( domain architecture ID 10640959)

scavenger receptor cysteine-rich (SRCR) domain-containing protein os a member of the group B scavenger receptor cysteine-rich family (SRCR-SF), composed of tandem-repeats of the SRCR domain

Graphical summary

 Zoom to residue level

show extra options »

Show site features     Horizontal zoom: ×

List of domain hits

 Name Accession Description Interval E-value
SR smart00202
Scavenger receptor Cys-rich; The sea urchin egg peptide speract contains 4 repeats of SR ...
 239-336 6.78e-31

Scavenger receptor Cys-rich; The sea urchin egg peptide speract contains 4 repeats of SR domains that contain 6 conserved cysteines. May bind bacterial antigens in the protein MARCO.


:

Pssm-ID: 214555 [Multi-domain]  Cd Length: 101  Bit Score: 114.36  E-value: 6.78e-31
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 30425310    239 RLLGGVHPCEGRLEVLRGLTWGTVCHDDLDLPMAHVVCRELGCGTAVSILGSSHFGYGSGPLWTEAFRCMGNESLLFHCL 318
Cdd:smart00202   2 RLVGGGSPCEGRVEVYHNGQWGTVCDDGWDLRDANVVCRQLGFGGAVSASGSAYFGPGSGPIWLDNVRCSGTEASLSDCP 81

                           90       100
                   ....*....|....*....|
gi 30425310    319 REP--GHQCGHDQDAALICS 336
Cdd:smart00202  82 HSGwgSHNCSHGEDAGVVCS 101
SR smart00202
Scavenger receptor Cys-rich; The sea urchin egg peptide speract contains 4 repeats of SR ...
 341-440 9.32e-28

Scavenger receptor Cys-rich; The sea urchin egg peptide speract contains 4 repeats of SR domains that contain 6 conserved cysteines. May bind bacterial antigens in the protein MARCO.


:

Pssm-ID: 214555 [Multi-domain]  Cd Length: 101  Bit Score: 105.89  E-value: 9.32e-28
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 30425310    341 RLVNGSSRCEGRVELLVQDAWQPLCAANWDLADATVLCHQLNCGYAVATPQGGHFGNVEGPIRTDVFHCVGTEPHLLSCP 420
Cdd:smart00202   2 RLVGGGSPCEGRVEVYHNGQWGTVCDDGWDLRDANVVCRQLGFGGAVSASGSAYFGPGSGPIWLDNVRCSGTEASLSDCP 81

                           90       100
                   ....*....|....*....|
gi 30425310    421 TSTLGAQACALGNSASALCS 440
Cdd:smart00202  82 HSGWGSHNCSHGEDAGVVCS 101
SR smart00202
Scavenger receptor Cys-rich; The sea urchin egg peptide speract contains 4 repeats of SR ...
 33-130 8.29e-20

Scavenger receptor Cys-rich; The sea urchin egg peptide speract contains 4 repeats of SR domains that contain 6 conserved cysteines. May bind bacterial antigens in the protein MARCO.


:

Pssm-ID: 214555 [Multi-domain]  Cd Length: 101  Bit Score: 83.93  E-value: 8.29e-20
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 30425310     33 GGDNKCEGQVRLRNGGQWGLMCADGLGMQEASVICRELGCGSVKFMPRYVLTPEEMRQPWLYDAQCHGNESTFLECRLGS 112
Cdd:smart00202   5 GGGSPCEGRVEVYHNGQWGTVCDDGWDLRDANVVCRQLGFGGAVSASGSAYFGPGSGPIWLDNVRCSGTEASLSDCPHSG 84

                           90
                   ....*....|....*...
gi 30425310    113 WGtISGCKCQCVAVITCS 130
Cdd:smart00202  85 WG-SHNCSHGEDAGVVCS 101
SR smart00202
Scavenger receptor Cys-rich; The sea urchin egg peptide speract contains 4 repeats of SR ...
 139-212 1.05e-05

Scavenger receptor Cys-rich; The sea urchin egg peptide speract contains 4 repeats of SR domains that contain 6 conserved cysteines. May bind bacterial antigens in the protein MARCO.


:

Pssm-ID: 214555 [Multi-domain]  Cd Length: 101  Bit Score: 43.87  E-value: 1.05e-05
                           10        20        30        40        50        60        70
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 30425310    139 LVDGGSPCAGTAQATGASNFALRCDLH--EKEAGVVCRQLECGTALQWS-RAHDGT-NGNQEQKYLTCQGTETNILQC 212
Cdd:smart00202   3 LVGGGSPCEGRVEVYHNGQWGTVCDDGwdLRDANVVCRQLGFGGAVSASgSAYFGPgSGPIWLDNVRCSGTEASLSDC 80
 
Name Accession Description Interval E-value
SR smart00202
Scavenger receptor Cys-rich; The sea urchin egg peptide speract contains 4 repeats of SR ...
 239-336 6.78e-31

Scavenger receptor Cys-rich; The sea urchin egg peptide speract contains 4 repeats of SR domains that contain 6 conserved cysteines. May bind bacterial antigens in the protein MARCO.


Pssm-ID: 214555 [Multi-domain]  Cd Length: 101  Bit Score: 114.36  E-value: 6.78e-31
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 30425310    239 RLLGGVHPCEGRLEVLRGLTWGTVCHDDLDLPMAHVVCRELGCGTAVSILGSSHFGYGSGPLWTEAFRCMGNESLLFHCL 318
Cdd:smart00202   2 RLVGGGSPCEGRVEVYHNGQWGTVCDDGWDLRDANVVCRQLGFGGAVSASGSAYFGPGSGPIWLDNVRCSGTEASLSDCP 81

                           90       100
                   ....*....|....*....|
gi 30425310    319 REP--GHQCGHDQDAALICS 336
Cdd:smart00202  82 HSGwgSHNCSHGEDAGVVCS 101
SR smart00202
Scavenger receptor Cys-rich; The sea urchin egg peptide speract contains 4 repeats of SR ...
 341-440 9.32e-28

Scavenger receptor Cys-rich; The sea urchin egg peptide speract contains 4 repeats of SR domains that contain 6 conserved cysteines. May bind bacterial antigens in the protein MARCO.


Pssm-ID: 214555 [Multi-domain]  Cd Length: 101  Bit Score: 105.89  E-value: 9.32e-28
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 30425310    341 RLVNGSSRCEGRVELLVQDAWQPLCAANWDLADATVLCHQLNCGYAVATPQGGHFGNVEGPIRTDVFHCVGTEPHLLSCP 420
Cdd:smart00202   2 RLVGGGSPCEGRVEVYHNGQWGTVCDDGWDLRDANVVCRQLGFGGAVSASGSAYFGPGSGPIWLDNVRCSGTEASLSDCP 81

                           90       100
                   ....*....|....*....|
gi 30425310    421 TSTLGAQACALGNSASALCS 440
Cdd:smart00202  82 HSGWGSHNCSHGEDAGVVCS 101
SRCR pfam00530
Scavenger receptor cysteine-rich domain; These domains are disulphide rich extracellular ...
 243-336 1.39e-26

Scavenger receptor cysteine-rich domain; These domains are disulphide rich extracellular domains. These domains are found in several extracellular receptors and may be involved in protein-protein interactions.


Pssm-ID: 459844  Cd Length: 98  Bit Score: 102.84  E-value: 1.39e-26
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 30425310   243 GVHPCEGRLEVLRGLTWGTVCHDDLDLPMAHVVCRELGCGTAVSILGS-SHFGYG-SGPLWTEAFRCMGNESLLFHCLRE 320
Cdd:pfam00530   1 GSSPCEGRVEVYHNGSWGTVCDDGWDLRDAHVVCRQLGCGGAVSAPSGcSYFGPGsTGPIWLDDVRCSGNETSLWQCPHR 80

                          90
                  ....*....|....*...
gi 30425310   321 P--GHQCGHDQDAALICS 336
Cdd:pfam00530  81 PwgNHNCSHSEDAGVICS 98
SRCR pfam00530
Scavenger receptor cysteine-rich domain; These domains are disulphide rich extracellular ...
 345-440 6.89e-20

Scavenger receptor cysteine-rich domain; These domains are disulphide rich extracellular domains. These domains are found in several extracellular receptors and may be involved in protein-protein interactions.


Pssm-ID: 459844  Cd Length: 98  Bit Score: 84.35  E-value: 6.89e-20
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 30425310   345 GSSRCEGRVELLVQDAWQPLCAANWDLADATVLCHQLNCGYAVATPQG-GHFGNVE-GPIRTDVFHCVGTEPHLLSCPTS 422
Cdd:pfam00530   1 GSSPCEGRVEVYHNGSWGTVCDDGWDLRDAHVVCRQLGCGGAVSAPSGcSYFGPGStGPIWLDDVRCSGNETSLWQCPHR 80

                          90
                  ....*....|....*...
gi 30425310   423 TLGAQACALGNSASALCS 440
Cdd:pfam00530  81 PWGNHNCSHSEDAGVICS 98
SR smart00202
Scavenger receptor Cys-rich; The sea urchin egg peptide speract contains 4 repeats of SR ...
 33-130 8.29e-20

Scavenger receptor Cys-rich; The sea urchin egg peptide speract contains 4 repeats of SR domains that contain 6 conserved cysteines. May bind bacterial antigens in the protein MARCO.


Pssm-ID: 214555 [Multi-domain]  Cd Length: 101  Bit Score: 83.93  E-value: 8.29e-20
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 30425310     33 GGDNKCEGQVRLRNGGQWGLMCADGLGMQEASVICRELGCGSVKFMPRYVLTPEEMRQPWLYDAQCHGNESTFLECRLGS 112
Cdd:smart00202   5 GGGSPCEGRVEVYHNGQWGTVCDDGWDLRDANVVCRQLGFGGAVSASGSAYFGPGSGPIWLDNVRCSGTEASLSDCPHSG 84

                           90
                   ....*....|....*...
gi 30425310    113 WGtISGCKCQCVAVITCS 130
Cdd:smart00202  85 WG-SHNCSHGEDAGVVCS 101
SRCR pfam00530
Scavenger receptor cysteine-rich domain; These domains are disulphide rich extracellular ...
 34-130 8.59e-17

Scavenger receptor cysteine-rich domain; These domains are disulphide rich extracellular domains. These domains are found in several extracellular receptors and may be involved in protein-protein interactions.


Pssm-ID: 459844  Cd Length: 98  Bit Score: 75.49  E-value: 8.59e-17
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 30425310    34 GDNKCEGQVRLRNGGQWGLMCADGLGMQEASVICRELGCGSVKFMPRYV--LTPEEMRQPWLYDAQCHGNESTFLECRLG 111
Cdd:pfam00530   1 GSSPCEGRVEVYHNGSWGTVCDDGWDLRDAHVVCRQLGCGGAVSAPSGCsyFGPGSTGPIWLDDVRCSGNETSLWQCPHR 80

                          90
                  ....*....|....*....
gi 30425310   112 SWGTiSGCKCQCVAVITCS 130
Cdd:pfam00530  81 PWGN-HNCSHSEDAGVICS 98
SR smart00202
Scavenger receptor Cys-rich; The sea urchin egg peptide speract contains 4 repeats of SR ...
 139-212 1.05e-05

Scavenger receptor Cys-rich; The sea urchin egg peptide speract contains 4 repeats of SR domains that contain 6 conserved cysteines. May bind bacterial antigens in the protein MARCO.


Pssm-ID: 214555 [Multi-domain]  Cd Length: 101  Bit Score: 43.87  E-value: 1.05e-05
                           10        20        30        40        50        60        70
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 30425310    139 LVDGGSPCAGTAQATGASNFALRCDLH--EKEAGVVCRQLECGTALQWS-RAHDGT-NGNQEQKYLTCQGTETNILQC 212
Cdd:smart00202   3 LVGGGSPCEGRVEVYHNGQWGTVCDDGwdLRDANVVCRQLGFGGAVSASgSAYFGPgSGPIWLDNVRCSGTEASLSDC 80
SRCR pfam00530
Scavenger receptor cysteine-rich domain; These domains are disulphide rich extracellular ...
 142-233 1.18e-05

Scavenger receptor cysteine-rich domain; These domains are disulphide rich extracellular domains. These domains are found in several extracellular receptors and may be involved in protein-protein interactions.


Pssm-ID: 459844  Cd Length: 98  Bit Score: 43.90  E-value: 1.18e-05
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 30425310   142 GGSPCAGTAQATGASNFALRCDLH--EKEAGVVCRQLECGTALQWSR----AHDGTNGNQEQKYLTCQGTETNILQCLIN 215
Cdd:pfam00530   1 GSSPCEGRVEVYHNGSWGTVCDDGwdLRDAHVVCRQLGCGGAVSAPSgcsyFGPGSTGPIWLDDVRCSGNETSLWQCPHR 80

                          90
                  ....*....|....*...
gi 30425310   216 VNVLEQCDLLTYTQVVCT 233
Cdd:pfam00530  81 PWGNHNCSHSEDAGVICS 98
 
Name Accession Description Interval E-value
SR smart00202
Scavenger receptor Cys-rich; The sea urchin egg peptide speract contains 4 repeats of SR ...
 239-336 6.78e-31

Scavenger receptor Cys-rich; The sea urchin egg peptide speract contains 4 repeats of SR domains that contain 6 conserved cysteines. May bind bacterial antigens in the protein MARCO.


Pssm-ID: 214555 [Multi-domain]  Cd Length: 101  Bit Score: 114.36  E-value: 6.78e-31
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 30425310    239 RLLGGVHPCEGRLEVLRGLTWGTVCHDDLDLPMAHVVCRELGCGTAVSILGSSHFGYGSGPLWTEAFRCMGNESLLFHCL 318
Cdd:smart00202   2 RLVGGGSPCEGRVEVYHNGQWGTVCDDGWDLRDANVVCRQLGFGGAVSASGSAYFGPGSGPIWLDNVRCSGTEASLSDCP 81

                           90       100
                   ....*....|....*....|
gi 30425310    319 REP--GHQCGHDQDAALICS 336
Cdd:smart00202  82 HSGwgSHNCSHGEDAGVVCS 101
SR smart00202
Scavenger receptor Cys-rich; The sea urchin egg peptide speract contains 4 repeats of SR ...
 341-440 9.32e-28

Scavenger receptor Cys-rich; The sea urchin egg peptide speract contains 4 repeats of SR domains that contain 6 conserved cysteines. May bind bacterial antigens in the protein MARCO.


Pssm-ID: 214555 [Multi-domain]  Cd Length: 101  Bit Score: 105.89  E-value: 9.32e-28
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 30425310    341 RLVNGSSRCEGRVELLVQDAWQPLCAANWDLADATVLCHQLNCGYAVATPQGGHFGNVEGPIRTDVFHCVGTEPHLLSCP 420
Cdd:smart00202   2 RLVGGGSPCEGRVEVYHNGQWGTVCDDGWDLRDANVVCRQLGFGGAVSASGSAYFGPGSGPIWLDNVRCSGTEASLSDCP 81

                           90       100
                   ....*....|....*....|
gi 30425310    421 TSTLGAQACALGNSASALCS 440
Cdd:smart00202  82 HSGWGSHNCSHGEDAGVVCS 101
SRCR pfam00530
Scavenger receptor cysteine-rich domain; These domains are disulphide rich extracellular ...
 243-336 1.39e-26

Scavenger receptor cysteine-rich domain; These domains are disulphide rich extracellular domains. These domains are found in several extracellular receptors and may be involved in protein-protein interactions.


Pssm-ID: 459844  Cd Length: 98  Bit Score: 102.84  E-value: 1.39e-26
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 30425310   243 GVHPCEGRLEVLRGLTWGTVCHDDLDLPMAHVVCRELGCGTAVSILGS-SHFGYG-SGPLWTEAFRCMGNESLLFHCLRE 320
Cdd:pfam00530   1 GSSPCEGRVEVYHNGSWGTVCDDGWDLRDAHVVCRQLGCGGAVSAPSGcSYFGPGsTGPIWLDDVRCSGNETSLWQCPHR 80

                          90
                  ....*....|....*...
gi 30425310   321 P--GHQCGHDQDAALICS 336
Cdd:pfam00530  81 PwgNHNCSHSEDAGVICS 98
SRCR pfam00530
Scavenger receptor cysteine-rich domain; These domains are disulphide rich extracellular ...
 345-440 6.89e-20

Scavenger receptor cysteine-rich domain; These domains are disulphide rich extracellular domains. These domains are found in several extracellular receptors and may be involved in protein-protein interactions.


Pssm-ID: 459844  Cd Length: 98  Bit Score: 84.35  E-value: 6.89e-20
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 30425310   345 GSSRCEGRVELLVQDAWQPLCAANWDLADATVLCHQLNCGYAVATPQG-GHFGNVE-GPIRTDVFHCVGTEPHLLSCPTS 422
Cdd:pfam00530   1 GSSPCEGRVEVYHNGSWGTVCDDGWDLRDAHVVCRQLGCGGAVSAPSGcSYFGPGStGPIWLDDVRCSGNETSLWQCPHR 80

                          90
                  ....*....|....*...
gi 30425310   423 TLGAQACALGNSASALCS 440
Cdd:pfam00530  81 PWGNHNCSHSEDAGVICS 98
SR smart00202
Scavenger receptor Cys-rich; The sea urchin egg peptide speract contains 4 repeats of SR ...
 33-130 8.29e-20

Scavenger receptor Cys-rich; The sea urchin egg peptide speract contains 4 repeats of SR domains that contain 6 conserved cysteines. May bind bacterial antigens in the protein MARCO.


Pssm-ID: 214555 [Multi-domain]  Cd Length: 101  Bit Score: 83.93  E-value: 8.29e-20
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 30425310     33 GGDNKCEGQVRLRNGGQWGLMCADGLGMQEASVICRELGCGSVKFMPRYVLTPEEMRQPWLYDAQCHGNESTFLECRLGS 112
Cdd:smart00202   5 GGGSPCEGRVEVYHNGQWGTVCDDGWDLRDANVVCRQLGFGGAVSASGSAYFGPGSGPIWLDNVRCSGTEASLSDCPHSG 84

                           90
                   ....*....|....*...
gi 30425310    113 WGtISGCKCQCVAVITCS 130
Cdd:smart00202  85 WG-SHNCSHGEDAGVVCS 101
SRCR pfam00530
Scavenger receptor cysteine-rich domain; These domains are disulphide rich extracellular ...
 34-130 8.59e-17

Scavenger receptor cysteine-rich domain; These domains are disulphide rich extracellular domains. These domains are found in several extracellular receptors and may be involved in protein-protein interactions.


Pssm-ID: 459844  Cd Length: 98  Bit Score: 75.49  E-value: 8.59e-17
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 30425310    34 GDNKCEGQVRLRNGGQWGLMCADGLGMQEASVICRELGCGSVKFMPRYV--LTPEEMRQPWLYDAQCHGNESTFLECRLG 111
Cdd:pfam00530   1 GSSPCEGRVEVYHNGSWGTVCDDGWDLRDAHVVCRQLGCGGAVSAPSGCsyFGPGSTGPIWLDDVRCSGNETSLWQCPHR 80

                          90
                  ....*....|....*....
gi 30425310   112 SWGTiSGCKCQCVAVITCS 130
Cdd:pfam00530  81 PWGN-HNCSHSEDAGVICS 98
SR smart00202
Scavenger receptor Cys-rich; The sea urchin egg peptide speract contains 4 repeats of SR ...
 139-212 1.05e-05

Scavenger receptor Cys-rich; The sea urchin egg peptide speract contains 4 repeats of SR domains that contain 6 conserved cysteines. May bind bacterial antigens in the protein MARCO.


Pssm-ID: 214555 [Multi-domain]  Cd Length: 101  Bit Score: 43.87  E-value: 1.05e-05
                           10        20        30        40        50        60        70
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 30425310    139 LVDGGSPCAGTAQATGASNFALRCDLH--EKEAGVVCRQLECGTALQWS-RAHDGT-NGNQEQKYLTCQGTETNILQC 212
Cdd:smart00202   3 LVGGGSPCEGRVEVYHNGQWGTVCDDGwdLRDANVVCRQLGFGGAVSASgSAYFGPgSGPIWLDNVRCSGTEASLSDC 80
SRCR pfam00530
Scavenger receptor cysteine-rich domain; These domains are disulphide rich extracellular ...
 142-233 1.18e-05

Scavenger receptor cysteine-rich domain; These domains are disulphide rich extracellular domains. These domains are found in several extracellular receptors and may be involved in protein-protein interactions.


Pssm-ID: 459844  Cd Length: 98  Bit Score: 43.90  E-value: 1.18e-05
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 30425310   142 GGSPCAGTAQATGASNFALRCDLH--EKEAGVVCRQLECGTALQWSR----AHDGTNGNQEQKYLTCQGTETNILQCLIN 215
Cdd:pfam00530   1 GSSPCEGRVEVYHNGSWGTVCDDGwdLRDAHVVCRQLGCGGAVSAPSgcsyFGPGSTGPIWLDDVRCSGNETSLWQCPHR 80

                          90
                  ....*....|....*...
gi 30425310   216 VNVLEQCDLLTYTQVVCT 233
Cdd:pfam00530  81 PWGNHNCSHSEDAGVICS 98
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
Help | Disclaimer | Write to the Help Desk
NCBI | NLM | NIH