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Conserved domains on  [gi|61098169|ref|NP_808537|]
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protein FAM185A isoform 1 [Mus musculus]

Protein Classification

DUF4097 family beta strand repeat-containing protein( domain architecture ID 1903587)

DUF4097 family beta strand repeat-containing protein similar to Homo sapiens protein FAM185A

Graphical summary

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List of domain hits

Name Accession Description Interval E-value
YvlB super family cl43909
Uncharacterized conserved protein YvlB, contains DUF4097 and DUF4098 domains [Function ...
206-314 2.57e-06

Uncharacterized conserved protein YvlB, contains DUF4097 and DUF4098 domains [Function unknown];


The actual alignment was detected with superfamily member COG3595:

Pssm-ID: 442814 [Multi-domain]  Cd Length: 254  Bit Score: 48.32  E-value: 2.57e-06
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 61098169 206 VSIEKLQGScVNISTEDGLLQAKYLYTESSFLSSAAGNIALGN-VHGNIILQSKMGNITVDSSCGCLKASSHQGAIDVYV 284
Cdd:COG3595  97 VTVEDLSGD-LTVKTVSGDIELSGLTGDEVELETVSGDITVKDgVGGDVEAKTVSGDITVDGASGSVEAKTVSGDIRLTL 175
                        90       100       110
                ....*....|....*....|....*....|..
gi 61098169 285 SQ--LGEVALTTEEGSIAVKAPSSLRAYFKLS 314
Cdd:COG3595 176 EGavAGRVKLKTVSGDVEVGLPEGTGADLDLS 207
 
Name Accession Description Interval E-value
YvlB COG3595
Uncharacterized conserved protein YvlB, contains DUF4097 and DUF4098 domains [Function ...
206-314 2.57e-06

Uncharacterized conserved protein YvlB, contains DUF4097 and DUF4098 domains [Function unknown];


Pssm-ID: 442814 [Multi-domain]  Cd Length: 254  Bit Score: 48.32  E-value: 2.57e-06
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 61098169 206 VSIEKLQGScVNISTEDGLLQAKYLYTESSFLSSAAGNIALGN-VHGNIILQSKMGNITVDSSCGCLKASSHQGAIDVYV 284
Cdd:COG3595  97 VTVEDLSGD-LTVKTVSGDIELSGLTGDEVELETVSGDITVKDgVGGDVEAKTVSGDITVDGASGSVEAKTVSGDIRLTL 175
                        90       100       110
                ....*....|....*....|....*....|..
gi 61098169 285 SQ--LGEVALTTEEGSIAVKAPSSLRAYFKLS 314
Cdd:COG3595 176 EGavAGRVKLKTVSGDVEVGLPEGTGADLDLS 207
DUF4097 pfam13349
Putative adhesin; This has a putative all-beta structure with a twenty-residue repeat with a ...
128-299 1.27e-04

Putative adhesin; This has a putative all-beta structure with a twenty-residue repeat with a highly conserved repeating GD, gly-asp, motif. It may form part of a bacterial adhesin.


Pssm-ID: 433135 [Multi-domain]  Cd Length: 246  Bit Score: 43.08  E-value: 1.27e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 61098169   128 VEVNAPVKFDLSIESSGSGSVKVQNIECDSCKIDTEQGTSILQSVKSQKLHVQTKGGDviccgtvygnidihasdkstVS 207
Cdd:pfam13349  89 ISVSDNLALKDVILSSNSGDITLKNVSAENLTIKSTSGDVSIDGSSAKKSKLITTSGD--------------------ID 148
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 61098169   208 IEKLQGSCVNISTEDGLLQAKYLY-TESSFLSSAAGNIalgnvhgNIILQSKmGNITVDsscgclkASSHQGAIDVYVSQ 286
Cdd:pfam13349 149 LNNVSGKDLDLKSTSGDINVSNTTiAGSLKITATSGDI-------DLSLPDS-ASFGVD-------ASSTSGDVTIPYKF 213
                         170
                  ....*....|...
gi 61098169   287 LGEvalTTEEGSI 299
Cdd:pfam13349 214 DEE---GTEENRI 223
 
Name Accession Description Interval E-value
YvlB COG3595
Uncharacterized conserved protein YvlB, contains DUF4097 and DUF4098 domains [Function ...
206-314 2.57e-06

Uncharacterized conserved protein YvlB, contains DUF4097 and DUF4098 domains [Function unknown];


Pssm-ID: 442814 [Multi-domain]  Cd Length: 254  Bit Score: 48.32  E-value: 2.57e-06
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 61098169 206 VSIEKLQGScVNISTEDGLLQAKYLYTESSFLSSAAGNIALGN-VHGNIILQSKMGNITVDSSCGCLKASSHQGAIDVYV 284
Cdd:COG3595  97 VTVEDLSGD-LTVKTVSGDIELSGLTGDEVELETVSGDITVKDgVGGDVEAKTVSGDITVDGASGSVEAKTVSGDIRLTL 175
                        90       100       110
                ....*....|....*....|....*....|..
gi 61098169 285 SQ--LGEVALTTEEGSIAVKAPSSLRAYFKLS 314
Cdd:COG3595 176 EGavAGRVKLKTVSGDVEVGLPEGTGADLDLS 207
DUF4097 pfam13349
Putative adhesin; This has a putative all-beta structure with a twenty-residue repeat with a ...
128-299 1.27e-04

Putative adhesin; This has a putative all-beta structure with a twenty-residue repeat with a highly conserved repeating GD, gly-asp, motif. It may form part of a bacterial adhesin.


Pssm-ID: 433135 [Multi-domain]  Cd Length: 246  Bit Score: 43.08  E-value: 1.27e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 61098169   128 VEVNAPVKFDLSIESSGSGSVKVQNIECDSCKIDTEQGTSILQSVKSQKLHVQTKGGDviccgtvygnidihasdkstVS 207
Cdd:pfam13349  89 ISVSDNLALKDVILSSNSGDITLKNVSAENLTIKSTSGDVSIDGSSAKKSKLITTSGD--------------------ID 148
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 61098169   208 IEKLQGSCVNISTEDGLLQAKYLY-TESSFLSSAAGNIalgnvhgNIILQSKmGNITVDsscgclkASSHQGAIDVYVSQ 286
Cdd:pfam13349 149 LNNVSGKDLDLKSTSGDINVSNTTiAGSLKITATSGDI-------DLSLPDS-ASFGVD-------ASSTSGDVTIPYKF 213
                         170
                  ....*....|...
gi 61098169   287 LGEvalTTEEGSI 299
Cdd:pfam13349 214 DEE---GTEENRI 223
YvlB COG3595
Uncharacterized conserved protein YvlB, contains DUF4097 and DUF4098 domains [Function ...
191-304 1.94e-04

Uncharacterized conserved protein YvlB, contains DUF4097 and DUF4098 domains [Function unknown];


Pssm-ID: 442814 [Multi-domain]  Cd Length: 254  Bit Score: 42.54  E-value: 1.94e-04
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 61098169 191 TVYGNIDIHASDKS----TVS----IEKLQGSCVNISTEDGLLQAKYLYTESSFLSSAAGNIALGNVHGNIILQSKMGNI 262
Cdd:COG3595  92 TSSGDVTVEDLSGDltvkTVSgdieLSGLTGDEVELETVSGDITVKDGVGGDVEAKTVSGDITVDGASGSVEAKTVSGDI 171
                        90       100       110       120
                ....*....|....*....|....*....|....*....|....*..
gi 61098169 263 TVD---SSCGCLKASSHQGAIDVYVSQLGEVALT--TEEGSIAVKAP 304
Cdd:COG3595 172 RLTlegAVAGRVKLKTVSGDVEVGLPEGTGADLDlsTVSGDIRVDLP 218
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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