NCBI Home Page NCBI Site Search page NCBI Guide that lists and describes the NCBI resources
Conserved domains on  [gi|161086982|ref|NP_852084|]
View 

zinc finger-like protein isoform 1 [Mus musculus]

Protein Classification

KRAB domain-containing zinc finger protein( domain architecture ID 12204378)

KRAB (Kruppel-associated box) domain-containing zinc finger protein (KRAB-ZFP) plays important roles in cell differentiation and organ development and in regulating viral replication and transcription

Graphical summary

 Zoom to residue level

show extra options »

Show site features     Horizontal zoom: ×

List of domain hits

 Name Accession Description Interval E-value
KRAB smart00349
krueppel associated box;
5-64 2.02e-30

krueppel associated box;


:

Pssm-ID: 214630 [Multi-domain]  Cd Length: 61  Bit Score: 113.07  E-value: 2.02e-30
                           10        20        30        40        50        60
                   ....*....|....*....|....*....|....*....|....*....|....*....|
gi 161086982     5 SFEDVAVDFTWEEWQDLDAAQRTLYRDVMLETYISLVSLGHCMNKPELIFKLEQGLGPWS 64
Cdd:smart00349   2 TFEDVAVYFTQEEWEQLDPAQKNLYRDVMLENYSNLVSLGFQVPKPDLISQLEQGEEPWI 61
COG5048 COG5048
FOG: Zn-finger [General function prediction only];
227-382 7.54e-09

FOG: Zn-finger [General function prediction only];


:

Pssm-ID: 227381 [Multi-domain]  Cd Length: 467  Bit Score: 58.17  E-value: 7.54e-09
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 161086982 227 PYKCKECGKAFCSQGKLTLHQ--IVHTGE--KPYECTE--CGKAFSHKAYLTQHQKIHMSKKPYAC--TECGKAFYRLSH 298
Cdd:COG5048  289 PIKSKQCNISFSRSSPLTRHLrsVNHSGEslKPFSCPYslCGKLFSRNDALKRHILLHTSISPAKEklLNSSSKFSPLLN 368

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 161086982 299 LTLHQRTH-----TNEKPYDCT--ECQKSFSCRSQLTLHQRTHTGERPFECM--ECGKSFYYKAHLIRHQRIHTNEKPFE 369
Cdd:COG5048  369 NEPPQSLQqykdlKNDKKSETLsnSCIRNFKRDSNLSLHIITHLSFRPYNCKnpPCSKSFNRHYNLIPHKKIHTNHAPLL 448

                        170
                 ....*....|...
gi 161086982 370 CIECEKSFYCQSD 382
Cdd:COG5048  449 CSILKSFRRDLDL 461
zf-H2C2_2 pfam13465
Zinc-finger double domain;
382-407 1.08e-03

Zinc-finger double domain;


:

Pssm-ID: 463886 [Multi-domain]  Cd Length: 26  Bit Score: 36.58  E-value: 1.08e-03
                          10        20
                  ....*....|....*....|....*.
gi 161086982  382 DLTVHQRSHTGEKPYECKECGKSFYQ 407
Cdd:pfam13465   1 NLKRHMRTHTGEKPYKCPECGKSFKS 26
 
Name Accession Description Interval E-value
KRAB smart00349
krueppel associated box;
5-64 2.02e-30

krueppel associated box;


Pssm-ID: 214630 [Multi-domain]  Cd Length: 61  Bit Score: 113.07  E-value: 2.02e-30
                           10        20        30        40        50        60
                   ....*....|....*....|....*....|....*....|....*....|....*....|
gi 161086982     5 SFEDVAVDFTWEEWQDLDAAQRTLYRDVMLETYISLVSLGHCMNKPELIFKLEQGLGPWS 64
Cdd:smart00349   2 TFEDVAVYFTQEEWEQLDPAQKNLYRDVMLENYSNLVSLGFQVPKPDLISQLEQGEEPWI 61
KRAB pfam01352
KRAB box; The KRAB domain (or Kruppel-associated box) is present in about a third of zinc ...
 3-44 1.94e-21

KRAB box; The KRAB domain (or Kruppel-associated box) is present in about a third of zinc finger proteins containing C2H2 fingers. The KRAB domain is found to be involved in protein-protein interactions. The KRAB domain is generally encoded by two exons. The regions coded by the two exons are known as KRAB-A and KRAB-B. The A box plays an important role in repression by binding to corepressors, while the B box is thought to enhance this repression brought about by the A box. KRAB-containing proteins are thought to have critical functions in cell proliferation and differentiation, apoptosis and neoplastic transformation.


Pssm-ID: 460171  Cd Length: 42  Bit Score: 87.14  E-value: 1.94e-21
                          10        20        30        40
                  ....*....|....*....|....*....|....*....|..
gi 161086982    3 LISFEDVAVDFTWEEWQDLDAAQRTLYRDVMLETYISLVSLG 44
Cdd:pfam01352   1 SVTFEDVAVDFTQEEWALLDPAQRNLYRDVMLENYRNLVSLG 42
KRAB_A-box cd07765
KRAB (Kruppel-associated box) domain -A box; The KRAB domain is a transcription repression ...
 4-43 1.39e-18

KRAB (Kruppel-associated box) domain -A box; The KRAB domain is a transcription repression module, found in a subgroup of the zinc finger proteins (ZFPs) of the C2H2 family, KRAB-ZFPs. KRAB-ZFPs comprise the largest group of transcriptional regulators in mammals, and are only found in tetrapods. These proteins have been shown to play important roles in cell differentiation and organ development, and in regulating viral replication and transcription. A KRAB domain may consist of an A-box, or of an A-box plus either a B-box, a divergent B-box (b), or a C-box. Only the A-box is included in this model. The A-box is needed for repression, the B- and C- boxes are not. KRAB-ZFPs have one or two KRAB domains at their amino-terminal end, and multiple C2H2 zinc finger motifs at their C-termini. Some KRAB-ZFPs also contain a SCAN domain which mediates homo- and hetero-oligomerization. The KRAB domain is a protein-protein interaction module which represses transcription through recruiting corepressors. A key mechanism appears to be the following: KRAB-AFPs tethered to DNA recruit, via their KRAB domain, the repressor KAP1 (KRAB-associated protein-1, also known as transcription intermediary factor 1 beta , KRAB-A interacting protein , and tripartite motif protein 28). The KAP1/ KRAB-AFP complex in turn recruits the heterochromatin protein 1 (HP1) family, and other chromatin modulating proteins, leading to transcriptional repression through heterochromatin formation.


Pssm-ID: 143639  Cd Length: 40  Bit Score: 79.13  E-value: 1.39e-18
                         10        20        30        40
                 ....*....|....*....|....*....|....*....|
gi 161086982   4 ISFEDVAVDFTWEEWQDLDAAQRTLYRDVMLETYISLVSL 43
Cdd:cd07765    1 VTFEDVAVYFSQEEWELLDPAQRDLYRDVMLENYENLVSL 40
COG5048 COG5048
FOG: Zn-finger [General function prediction only];
227-382 7.54e-09

FOG: Zn-finger [General function prediction only];


Pssm-ID: 227381 [Multi-domain]  Cd Length: 467  Bit Score: 58.17  E-value: 7.54e-09
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 161086982 227 PYKCKECGKAFCSQGKLTLHQ--IVHTGE--KPYECTE--CGKAFSHKAYLTQHQKIHMSKKPYAC--TECGKAFYRLSH 298
Cdd:COG5048  289 PIKSKQCNISFSRSSPLTRHLrsVNHSGEslKPFSCPYslCGKLFSRNDALKRHILLHTSISPAKEklLNSSSKFSPLLN 368

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 161086982 299 LTLHQRTH-----TNEKPYDCT--ECQKSFSCRSQLTLHQRTHTGERPFECM--ECGKSFYYKAHLIRHQRIHTNEKPFE 369
Cdd:COG5048  369 NEPPQSLQqykdlKNDKKSETLsnSCIRNFKRDSNLSLHIITHLSFRPYNCKnpPCSKSFNRHYNLIPHKKIHTNHAPLL 448

                        170
                 ....*....|...
gi 161086982 370 CIECEKSFYCQSD 382
Cdd:COG5048  449 CSILKSFRRDLDL 461
zf-H2C2_2 pfam13465
Zinc-finger double domain;
354-379 7.66e-04

Zinc-finger double domain;


Pssm-ID: 463886 [Multi-domain]  Cd Length: 26  Bit Score: 36.97  E-value: 7.66e-04
                          10        20
                  ....*....|....*....|....*.
gi 161086982  354 HLIRHQRIHTNEKPFECIECEKSFYC 379
Cdd:pfam13465   1 NLKRHMRTHTGEKPYKCPECGKSFKS 26
zf-H2C2_2 pfam13465
Zinc-finger double domain;
382-407 1.08e-03

Zinc-finger double domain;


Pssm-ID: 463886 [Multi-domain]  Cd Length: 26  Bit Score: 36.58  E-value: 1.08e-03
                          10        20
                  ....*....|....*....|....*.
gi 161086982  382 DLTVHQRSHTGEKPYECKECGKSFYQ 407
Cdd:pfam13465   1 NLKRHMRTHTGEKPYKCPECGKSFKS 26
 
Name Accession Description Interval E-value
KRAB smart00349
krueppel associated box;
5-64 2.02e-30

krueppel associated box;


Pssm-ID: 214630 [Multi-domain]  Cd Length: 61  Bit Score: 113.07  E-value: 2.02e-30
                           10        20        30        40        50        60
                   ....*....|....*....|....*....|....*....|....*....|....*....|
gi 161086982     5 SFEDVAVDFTWEEWQDLDAAQRTLYRDVMLETYISLVSLGHCMNKPELIFKLEQGLGPWS 64
Cdd:smart00349   2 TFEDVAVYFTQEEWEQLDPAQKNLYRDVMLENYSNLVSLGFQVPKPDLISQLEQGEEPWI 61
KRAB pfam01352
KRAB box; The KRAB domain (or Kruppel-associated box) is present in about a third of zinc ...
 3-44 1.94e-21

KRAB box; The KRAB domain (or Kruppel-associated box) is present in about a third of zinc finger proteins containing C2H2 fingers. The KRAB domain is found to be involved in protein-protein interactions. The KRAB domain is generally encoded by two exons. The regions coded by the two exons are known as KRAB-A and KRAB-B. The A box plays an important role in repression by binding to corepressors, while the B box is thought to enhance this repression brought about by the A box. KRAB-containing proteins are thought to have critical functions in cell proliferation and differentiation, apoptosis and neoplastic transformation.


Pssm-ID: 460171  Cd Length: 42  Bit Score: 87.14  E-value: 1.94e-21
                          10        20        30        40
                  ....*....|....*....|....*....|....*....|..
gi 161086982    3 LISFEDVAVDFTWEEWQDLDAAQRTLYRDVMLETYISLVSLG 44
Cdd:pfam01352   1 SVTFEDVAVDFTQEEWALLDPAQRNLYRDVMLENYRNLVSLG 42
KRAB_A-box cd07765
KRAB (Kruppel-associated box) domain -A box; The KRAB domain is a transcription repression ...
 4-43 1.39e-18

KRAB (Kruppel-associated box) domain -A box; The KRAB domain is a transcription repression module, found in a subgroup of the zinc finger proteins (ZFPs) of the C2H2 family, KRAB-ZFPs. KRAB-ZFPs comprise the largest group of transcriptional regulators in mammals, and are only found in tetrapods. These proteins have been shown to play important roles in cell differentiation and organ development, and in regulating viral replication and transcription. A KRAB domain may consist of an A-box, or of an A-box plus either a B-box, a divergent B-box (b), or a C-box. Only the A-box is included in this model. The A-box is needed for repression, the B- and C- boxes are not. KRAB-ZFPs have one or two KRAB domains at their amino-terminal end, and multiple C2H2 zinc finger motifs at their C-termini. Some KRAB-ZFPs also contain a SCAN domain which mediates homo- and hetero-oligomerization. The KRAB domain is a protein-protein interaction module which represses transcription through recruiting corepressors. A key mechanism appears to be the following: KRAB-AFPs tethered to DNA recruit, via their KRAB domain, the repressor KAP1 (KRAB-associated protein-1, also known as transcription intermediary factor 1 beta , KRAB-A interacting protein , and tripartite motif protein 28). The KAP1/ KRAB-AFP complex in turn recruits the heterochromatin protein 1 (HP1) family, and other chromatin modulating proteins, leading to transcriptional repression through heterochromatin formation.


Pssm-ID: 143639  Cd Length: 40  Bit Score: 79.13  E-value: 1.39e-18
                         10        20        30        40
                 ....*....|....*....|....*....|....*....|
gi 161086982   4 ISFEDVAVDFTWEEWQDLDAAQRTLYRDVMLETYISLVSL 43
Cdd:cd07765    1 VTFEDVAVYFSQEEWELLDPAQRDLYRDVMLENYENLVSL 40
COG5048 COG5048
FOG: Zn-finger [General function prediction only];
227-382 7.54e-09

FOG: Zn-finger [General function prediction only];


Pssm-ID: 227381 [Multi-domain]  Cd Length: 467  Bit Score: 58.17  E-value: 7.54e-09
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 161086982 227 PYKCKECGKAFCSQGKLTLHQ--IVHTGE--KPYECTE--CGKAFSHKAYLTQHQKIHMSKKPYAC--TECGKAFYRLSH 298
Cdd:COG5048  289 PIKSKQCNISFSRSSPLTRHLrsVNHSGEslKPFSCPYslCGKLFSRNDALKRHILLHTSISPAKEklLNSSSKFSPLLN 368

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 161086982 299 LTLHQRTH-----TNEKPYDCT--ECQKSFSCRSQLTLHQRTHTGERPFECM--ECGKSFYYKAHLIRHQRIHTNEKPFE 369
Cdd:COG5048  369 NEPPQSLQqykdlKNDKKSETLsnSCIRNFKRDSNLSLHIITHLSFRPYNCKnpPCSKSFNRHYNLIPHKKIHTNHAPLL 448

                        170
                 ....*....|...
gi 161086982 370 CIECEKSFYCQSD 382
Cdd:COG5048  449 CSILKSFRRDLDL 461
COG5048 COG5048
FOG: Zn-finger [General function prediction only];
261-504 2.12e-06

FOG: Zn-finger [General function prediction only];


Pssm-ID: 227381 [Multi-domain]  Cd Length: 467  Bit Score: 50.46  E-value: 2.12e-06
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 161086982 261 CGKAFSHKAYLTQHQKIHMSKKPYACTECGKaFYRLSHLTLHQRTHTNEKPYDCTECQKSFSCRSQLTLHQRTHTGERPF 340
Cdd:COG5048  177 SKDPSSNLSLLISSNVSTSIPSSSENSPLSS-SYSIPSSSSDQNLENSSSSLPLTTNSQLSPKSLLSQSPSSLSSSDSSS 255

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 161086982 341 ECMECGKSFYYKAHLIRHQRIHTNE-------KPFECIECEKSFYCQSDLTVHQRS--HTGE--KPYECKE--CGKSFYQ 407
Cdd:COG5048  256 SASESPRSSLPTASSQSSSPNESDSssekgfsLPIKSKQCNISFSRSSPLTRHLRSvnHSGEslKPFSCPYslCGKLFSR 335

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 161086982 408 KSKLTLHQRNHVGEKSYAC--TDCGEVFY----CKSHLTLHQTVHTDE-HPYICTECGKCFYYKSQLIV--HGRTHTGDR 478
Cdd:COG5048  336 NDALKRHILLHTSISPAKEklLNSSSKFSpllnNEPPQSLQQYKDLKNdKKSETLSNSCIRNFKRDSNLslHIITHLSFR 415

                        250       260
                 ....*....|....*....|....*...
gi 161086982 479 P--YKCGDCGKAFSRKSHLIRHQSITHI 504
Cdd:COG5048  416 PynCKNPPCSKSFNRHYNLIPHKKIHTN 443
COG5048 COG5048
FOG: Zn-finger [General function prediction only];
269-354 4.32e-06

FOG: Zn-finger [General function prediction only];


Pssm-ID: 227381 [Multi-domain]  Cd Length: 467  Bit Score: 49.31  E-value: 4.32e-06
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 161086982 269 AYLTQHQKIHMSKKPYACTECGKAFYRLSHLTLHQRTHTNEKPYDCT--ECQKSFSCRSQLTLHQRTHTGERPFEC-MEC 345
Cdd:COG5048   19 TPKSTLKSLSNAPRPDSCPNCTDSFSRLEHLTRHIRSHTGEKPSQCSysGCDKSFSRPLELSRHLRTHHNNPSDLNsKSL 98


                 ....*....
gi 161086982 346 GKSFYYKAH 354
Cdd:COG5048   99 PLSNSKASS 107
COG5048 COG5048
FOG: Zn-finger [General function prediction only];
207-546 2.93e-05

FOG: Zn-finger [General function prediction only];


Pssm-ID: 227381 [Multi-domain]  Cd Length: 467  Bit Score: 46.61  E-value: 2.93e-05
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 161086982 207 KDFSCNSKLTSHPRTRIRK------RPYKCKECGKAFCSQGKLTLHQIVHTGEKPYECT--ECGKAFSHKAYLTQHQKIH 278
Cdd:COG5048    7 QSSSSNNSVLSSTPKSTLKslsnapRPDSCPNCTDSFSRLEHLTRHIRSHTGEKPSQCSysGCDKSFSRPLELSRHLRTH 86

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 161086982 279 MSKKPYAC----------------TECGKAFYRLSHLTLHQ-------------RTHTNEKPYDCTECQKSFSCRSQ--- 326
Cdd:COG5048   87 HNNPSDLNskslplsnskasssslSSSSSNSNDNNLLSSHSlppssrdpqlpdlLSISNLRNNPLPGNNSSSVNTPQsns 166

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 161086982 327 -------------------LTLHQRTHTGERPFECMECGKSFYYKAHLIRHQRIHTNEKPFECIECekSFYCQSDLTVHQ 387
Cdd:COG5048  167 lhpplpanslskdpssnlsLLISSNVSTSIPSSSENSPLSSSYSIPSSSSDQNLENSSSSLPLTTN--SQLSPKSLLSQS 244

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 161086982 388 RSHTGEK--PYECKECGKSFYQKSKLTLHQRNHVGE-------KSYACTDCGEVFYCKSHLTLHQ--TVHTDEH--PYIC 454
Cdd:COG5048  245 PSSLSSSdsSSSASESPRSSLPTASSQSSSPNESDSssekgfsLPIKSKQCNISFSRSSPLTRHLrsVNHSGESlkPFSC 324

                        330       340       350       360       370       380       390       400
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 161086982 455 TE--CGKCFYYKSQLIVHGRTHTGDRPYKC--GDCGKAFSRKSH-----LIRHQSITHIDKNNLNVANVGKVSTVR---- 521
Cdd:COG5048  325 PYslCGKLFSRNDALKRHILLHTSISPAKEklLNSSSKFSPLLNneppqSLQQYKDLKNDKKSETLSNSCIRNFKRdsnl 404

                        410       420
                 ....*....|....*....|....*
gi 161086982 522 PDSLHTHSLYLSEHKHAPSILKEKN 546
Cdd:COG5048  405 SLHIITHLSFRPYNCKNPPCSKSFN 429
COG5048 COG5048
FOG: Zn-finger [General function prediction only];
291-498 5.96e-05

FOG: Zn-finger [General function prediction only];


Pssm-ID: 227381 [Multi-domain]  Cd Length: 467  Bit Score: 45.84  E-value: 5.96e-05
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 161086982 291 KAFYRLSHLTLHQRTHTN-EKPYDCTECQKSFSCRSQLTLHQRT--HTGE--RPFECME--CGKSFYYKAHLIRHQRIHT 363
Cdd:COG5048  268 ASSQSSSPNESDSSSEKGfSLPIKSKQCNISFSRSSPLTRHLRSvnHSGEslKPFSCPYslCGKLFSRNDALKRHILLHT 347

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 161086982 364 NEKPFECIeceksfycqsdLTVHQRSHTGEKPyeckECGKSFYQKSKLTLHQRNHVGEKSyactDCGEVFYCKSHLTLHQ 443
Cdd:COG5048  348 SISPAKEK-----------LLNSSSKFSPLLN----NEPPQSLQQYKDLKNDKKSETLSN----SCIRNFKRDSNLSLHI 408

                        170       180       190       200       210
                 ....*....|....*....|....*....|....*....|....*....|....*..
gi 161086982 444 TVHT--DEHPYICTECGKCFYYKSQLIVHGRTHTGDRPYKCGDCGKaFSRKSHLIRH 498
Cdd:COG5048  409 ITHLsfRPYNCKNPPCSKSFNRHYNLIPHKKIHTNHAPLLCSILKS-FRRDLDLSNH 464
zf-H2C2_2 pfam13465
Zinc-finger double domain;
354-379 7.66e-04

Zinc-finger double domain;


Pssm-ID: 463886 [Multi-domain]  Cd Length: 26  Bit Score: 36.97  E-value: 7.66e-04
                          10        20
                  ....*....|....*....|....*.
gi 161086982  354 HLIRHQRIHTNEKPFECIECEKSFYC 379
Cdd:pfam13465   1 NLKRHMRTHTGEKPYKCPECGKSFKS 26
zf-H2C2_2 pfam13465
Zinc-finger double domain;
382-407 1.08e-03

Zinc-finger double domain;


Pssm-ID: 463886 [Multi-domain]  Cd Length: 26  Bit Score: 36.58  E-value: 1.08e-03
                          10        20
                  ....*....|....*....|....*.
gi 161086982  382 DLTVHQRSHTGEKPYECKECGKSFYQ 407
Cdd:pfam13465   1 NLKRHMRTHTGEKPYKCPECGKSFKS 26
zf-H2C2_2 pfam13465
Zinc-finger double domain;
327-351 3.51e-03

Zinc-finger double domain;


Pssm-ID: 463886 [Multi-domain]  Cd Length: 26  Bit Score: 35.04  E-value: 3.51e-03
                          10        20
                  ....*....|....*....|....*
gi 161086982  327 LTLHQRTHTGERPFECMECGKSFYY 351
Cdd:pfam13465   2 LKRHMRTHTGEKPYKCPECGKSFKS 26
zf-H2C2_2 pfam13465
Zinc-finger double domain;
298-323 6.52e-03

Zinc-finger double domain;


Pssm-ID: 463886 [Multi-domain]  Cd Length: 26  Bit Score: 34.27  E-value: 6.52e-03
                          10        20
                  ....*....|....*....|....*.
gi 161086982  298 HLTLHQRTHTNEKPYDCTECQKSFSC 323
Cdd:pfam13465   1 NLKRHMRTHTGEKPYKCPECGKSFKS 26
zf-H2C2_2 pfam13465
Zinc-finger double domain;
243-267 8.25e-03

Zinc-finger double domain;


Pssm-ID: 463886 [Multi-domain]  Cd Length: 26  Bit Score: 33.88  E-value: 8.25e-03
                          10        20
                  ....*....|....*....|....*
gi 161086982  243 LTLHQIVHTGEKPYECTECGKAFSH 267
Cdd:pfam13465   2 LKRHMRTHTGEKPYKCPECGKSFKS 26
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
Help | Disclaimer | Write to the Help Desk
NCBI | NLM | NIH