NCBI Home Page NCBI Site Search page NCBI Guide that lists and describes the NCBI resources
Conserved domains on  [gi|47058950|ref|NP_997623|]
View 

1-acyl-sn-glycerol-3-phosphate acyltransferase alpha [Rattus norvegicus]

Protein Classification

Graphical summary

 Zoom to residue level

show extra options »

Show site features     Horizontal zoom: ×

List of domain hits

 Name Accession Description Interval E-value
LPLAT_AGPAT-like cd07989
Lysophospholipid Acyltransferases (LPLATs) of Glycerophospholipid Biosynthesis: AGPAT-like; ...
 66-252 3.88e-58

Lysophospholipid Acyltransferases (LPLATs) of Glycerophospholipid Biosynthesis: AGPAT-like; Lysophospholipid acyltransferase (LPLAT) superfamily member: acyltransferases of de novo and remodeling pathways of glycerophospholipid biosynthesis which catalyze the incorporation of an acyl group from either acylCoAs or acyl-acyl carrier proteins (acylACPs) into acceptors such as glycerol 3-phosphate, dihydroxyacetone phosphate or lyso-phosphatidic acid. Included in this subgroup are such LPLATs as 1-acyl-sn-glycerol-3-phosphate acyltransferase (AGPAT, PlsC), Tafazzin (product of Barth syndrome gene), and similar proteins.


:

Pssm-ID: 153251 [Multi-domain]  Cd Length: 184  Bit Score: 184.01  E-value: 3.88e-58
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 47058950  66 LRLLLlhvkYLYGIRVEVRGAQHFPPTQPYVVVSNHQSSLDLLGMMEVLPDRCVPIAKRELLWAGSAGLACWLAGVIFID 145
Cdd:cd07989   1 LRLLL----RLLGVRVRVEGLENLPPKGPVIIVANHQSYLDPLVLGAALPRPIRFVAKKELFKIPFLGWLLRLLGAIPID 76

                        90       100       110       120       130       140       150       160
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 47058950 146 RKRTGDAISVMSEVAQtLLTQDVRVWVFPEGTRNHNGSMLPFKRGAFHLAVQAQVPIVPIVMSSYQDFYCKKERRFTSGR 225
Cdd:cd07989  77 RGNGRSAREALREAIE-ALKEGESVVIFPEGTRSRDGELLPFKSGAFRLAKEAGVPIVPVAISGTWGSLPKGKKLPRPGR 155

                       170       180
                ....*....|....*....|....*....
gi 47058950 226 CQVRVLPPVPTEGL--TPDDVPALADRVR 252
Cdd:cd07989 156 VTVRIGEPIPPEGLelAEEDRKELREKVR 184
 
Name Accession Description Interval E-value
LPLAT_AGPAT-like cd07989
Lysophospholipid Acyltransferases (LPLATs) of Glycerophospholipid Biosynthesis: AGPAT-like; ...
 66-252 3.88e-58

Lysophospholipid Acyltransferases (LPLATs) of Glycerophospholipid Biosynthesis: AGPAT-like; Lysophospholipid acyltransferase (LPLAT) superfamily member: acyltransferases of de novo and remodeling pathways of glycerophospholipid biosynthesis which catalyze the incorporation of an acyl group from either acylCoAs or acyl-acyl carrier proteins (acylACPs) into acceptors such as glycerol 3-phosphate, dihydroxyacetone phosphate or lyso-phosphatidic acid. Included in this subgroup are such LPLATs as 1-acyl-sn-glycerol-3-phosphate acyltransferase (AGPAT, PlsC), Tafazzin (product of Barth syndrome gene), and similar proteins.


Pssm-ID: 153251 [Multi-domain]  Cd Length: 184  Bit Score: 184.01  E-value: 3.88e-58
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 47058950  66 LRLLLlhvkYLYGIRVEVRGAQHFPPTQPYVVVSNHQSSLDLLGMMEVLPDRCVPIAKRELLWAGSAGLACWLAGVIFID 145
Cdd:cd07989   1 LRLLL----RLLGVRVRVEGLENLPPKGPVIIVANHQSYLDPLVLGAALPRPIRFVAKKELFKIPFLGWLLRLLGAIPID 76

                        90       100       110       120       130       140       150       160
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 47058950 146 RKRTGDAISVMSEVAQtLLTQDVRVWVFPEGTRNHNGSMLPFKRGAFHLAVQAQVPIVPIVMSSYQDFYCKKERRFTSGR 225
Cdd:cd07989  77 RGNGRSAREALREAIE-ALKEGESVVIFPEGTRSRDGELLPFKSGAFRLAKEAGVPIVPVAISGTWGSLPKGKKLPRPGR 155

                       170       180
                ....*....|....*....|....*....
gi 47058950 226 CQVRVLPPVPTEGL--TPDDVPALADRVR 252
Cdd:cd07989 156 VTVRIGEPIPPEGLelAEEDRKELREKVR 184
PlsC COG0204
1-acyl-sn-glycerol-3-phosphate acyltransferase [Lipid transport and metabolism]; ...
 64-265 3.19e-57

1-acyl-sn-glycerol-3-phosphate acyltransferase [Lipid transport and metabolism]; 1-acyl-sn-glycerol-3-phosphate acyltransferase is part of the Pathway/BioSystem: Phospholipid biosynthesis


Pssm-ID: 439974 [Multi-domain]  Cd Length: 215  Bit Score: 182.90  E-value: 3.19e-57
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 47058950  64 KILRLLLLHVKYLYGIRVEVRGAQHFPPTQPYVVVSNHQSSLDLLGMMEVLPDRCVPIAKRELLWAGSAGLACWLAGVIF 143
Cdd:COG0204  14 RLVRLWARLLLRLLGVRVRVEGLENLPADGPVLIVANHQSWLDILLLLAALPRPVRFVAKKELFKIPLLGWLLRALGAIP 93

                        90       100       110       120       130       140       150       160
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 47058950 144 IDRKRTGDAISVMSEVAQtLLTQDVRVWVFPEGTRNHNGSMLPFKRGAFHLAVQAQVPIVPIVMSSYQDFYCKKeRRFTS 223
Cdd:COG0204  94 VDRSKRRAALRALRQAVE-ALKAGESLVIFPEGTRSPDGRLLPFKTGAARLALEAGVPIVPVAIDGTERALPKG-FLPRP 171

                       170       180       190       200
                ....*....|....*....|....*....|....*....|..
gi 47058950 224 GRCQVRVLPPVPTEGLTPDDVPALADRVRHSMLTIFREISTD 265
Cdd:COG0204 172 GKVTVRIGPPIDPSDLEGEDRRELAERLRAAIEALLAELRAE 213
Acyltransferase pfam01553
Acyltransferase; This family contains acyltransferases involved in phospholipid biosynthesis ...
 80-208 6.72e-44

Acyltransferase; This family contains acyltransferases involved in phospholipid biosynthesis and other proteins of unknown function. This family also includes tafazzin, the Barth syndrome gene.


Pssm-ID: 366704 [Multi-domain]  Cd Length: 131  Bit Score: 145.50  E-value: 6.72e-44
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 47058950    80 RVEVRGAQHFPPTQPYVVVSNHQSSLDLLGMMEVLPD---RCVPIAKRELLWAGSAGLACWLAGVIFIDRKRTGDAISVM 156
Cdd:pfam01553   1 RIEVHGLENLPRGGPAIVVANHQSYLDVLLLSLALYKrgrPLVFVAKKELFDIPLVGWLMRLLGCIFIDRKNRKDAAGTL 80

                          90       100       110       120       130
                  ....*....|....*....|....*....|....*....|....*....|..
gi 47058950   157 SEVAQtLLTQDVRVWVFPEGTRNHNGSMLPFKRGAFHLAVQAQVPIVPIVMS 208
Cdd:pfam01553  81 EYLVE-LLREGKLVVIFPEGTRSREGELLPFKKGAFRLAIEAGVPIVPVAIS 131
AGP_acyltrn TIGR00530
1-acyl-sn-glycerol-3-phosphate acyltransferases; This model describes the core homologous ...
 78-208 3.11e-41

1-acyl-sn-glycerol-3-phosphate acyltransferases; This model describes the core homologous region of a collection of related proteins, several of which are known to act as 1-acyl-sn-glycerol-3-phosphate acyltransferases (EC 2.3.1.51). Proteins scoring above the trusted cutoff are likely to have the same general activity. However, there is variation among characterized members as to whether the acyl group can be donated by acyl carrier protein or coenzyme A, and in the length and saturation of the donated acyl group. 1-acyl-sn-glycerol-3-phosphate acyltransferase is also called 1-AGP acyltransferase, lysophosphatidic acid acyltransferase, and LPA acyltransferase. [Fatty acid and phospholipid metabolism, Biosynthesis]


Pssm-ID: 129621 [Multi-domain]  Cd Length: 130  Bit Score: 138.63  E-value: 3.11e-41
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 47058950    78 GIRVEVRGAQHFPPTQPYVVVSNHQSSLDLLGMMEVLPDRCVPIAKRELLWAGSAGLACWLAGVIFIDRKRTgDAISVMS 157
Cdd:TIGR00530   1 GLKVEVVGPENLPAKSPVLVVANHQSNLDPLTLSAAFPPPIVFIAKKELKWIPFFGIMLWLTGAIFIDRENI-RAIATAL 79

                          90       100       110       120       130
                  ....*....|....*....|....*....|....*....|....*....|.
gi 47058950   158 EVAQTLLTQDVRVWVFPEGTRNHNGSMLPFKRGAFHLAVQAQVPIVPIVMS 208
Cdd:TIGR00530  80 KAAIEVLKQGRSIGVFPEGTRSRGRDILPFKKGAFHIAIKAGVPILPVVLS 130
PlsC smart00563
Phosphate acyltransferases; Function in phospholipid biosynthesis and have either ...
 95-208 5.82e-36

Phosphate acyltransferases; Function in phospholipid biosynthesis and have either glycerolphosphate, 1-acylglycerolphosphate, or 2-acylglycerolphosphoethanolamine acyltransferase activities. Tafazzin, the product of the gene mutated in patients with Barth syndrome, is a member of this family.


Pssm-ID: 214724 [Multi-domain]  Cd Length: 118  Bit Score: 124.77  E-value: 5.82e-36
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 47058950     95 YVVVSNHQSSLDLLGMMEVLPD---RCVPIAKRELLWAGSAGLACWLAGVIFIDRKRTGDAISVMSEVAQtLLTQDVRVW 171
Cdd:smart00563   1 ALVVANHQSFLDPLVLSALLPRklgRVRFVAKKELFYVPLLGWLLRLLGAIFIDRSNGRKARAALREAVE-LLKEGEWLL 79

                           90       100       110
                   ....*....|....*....|....*....|....*..
gi 47058950    172 VFPEGTRNHNGSMLPFKRGAFHLAVQAQVPIVPIVMS 208
Cdd:smart00563  80 IFPEGTRSRPGKLLPFKKGAARLALEAGVPIVPVAIR 116
PRK15018 PRK15018
1-acyl-sn-glycerol-3-phosphate acyltransferase; Provisional
 31-255 1.86e-28

1-acyl-sn-glycerol-3-phosphate acyltransferase; Provisional


Pssm-ID: 184979  Cd Length: 245  Bit Score: 109.33  E-value: 1.86e-28
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 47058950   31 YFFKMAFYNGWILFLAILAIPVCAVRGRNVENMKILRLLLLHVKYLYGIRVEVRGAQHFPPTQPYVVVSNHQSSLDLLGM 110
Cdd:PRK15018   3 YIFRLIITVIYSILVCVFGSIYCLFSPRNPKHVATFGHMFGRLAPLFGLKVECRKPADAESYGNAIYIANHQNNYDMVTA 82

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 47058950  111 MEVLPDRCVPIAKRELLWAGSAGLACWLAGVIFIDRKRTGDAISVMSEVAQTLLTQDVRVWVFPEGTRNHNGSMLPFKRG 190
Cdd:PRK15018  83 SNIVQPPTVTVGKKSLLWIPFFGQLYWLTGNLLIDRNNRTKAHGTIAEVVNHFKKRRISIWMFPEGTRSRGRGLLPFKTG 162

                        170       180       190       200       210       220
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 47058950  191 AFHLAVQAQVPIVPIVMSSYQDFYckKERRFTSGRCQVRVLPPVPTEGLTPDDVPALADRVRHSM 255
Cdd:PRK15018 163 AFHAAIAAGVPIIPVCVSTTSNKI--NLNRLHNGLVIVEMLPPIDVSQYGKDQVRELAAHCRSIM 225
 
Name Accession Description Interval E-value
LPLAT_AGPAT-like cd07989
Lysophospholipid Acyltransferases (LPLATs) of Glycerophospholipid Biosynthesis: AGPAT-like; ...
 66-252 3.88e-58

Lysophospholipid Acyltransferases (LPLATs) of Glycerophospholipid Biosynthesis: AGPAT-like; Lysophospholipid acyltransferase (LPLAT) superfamily member: acyltransferases of de novo and remodeling pathways of glycerophospholipid biosynthesis which catalyze the incorporation of an acyl group from either acylCoAs or acyl-acyl carrier proteins (acylACPs) into acceptors such as glycerol 3-phosphate, dihydroxyacetone phosphate or lyso-phosphatidic acid. Included in this subgroup are such LPLATs as 1-acyl-sn-glycerol-3-phosphate acyltransferase (AGPAT, PlsC), Tafazzin (product of Barth syndrome gene), and similar proteins.


Pssm-ID: 153251 [Multi-domain]  Cd Length: 184  Bit Score: 184.01  E-value: 3.88e-58
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 47058950  66 LRLLLlhvkYLYGIRVEVRGAQHFPPTQPYVVVSNHQSSLDLLGMMEVLPDRCVPIAKRELLWAGSAGLACWLAGVIFID 145
Cdd:cd07989   1 LRLLL----RLLGVRVRVEGLENLPPKGPVIIVANHQSYLDPLVLGAALPRPIRFVAKKELFKIPFLGWLLRLLGAIPID 76

                        90       100       110       120       130       140       150       160
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 47058950 146 RKRTGDAISVMSEVAQtLLTQDVRVWVFPEGTRNHNGSMLPFKRGAFHLAVQAQVPIVPIVMSSYQDFYCKKERRFTSGR 225
Cdd:cd07989  77 RGNGRSAREALREAIE-ALKEGESVVIFPEGTRSRDGELLPFKSGAFRLAKEAGVPIVPVAISGTWGSLPKGKKLPRPGR 155

                       170       180
                ....*....|....*....|....*....
gi 47058950 226 CQVRVLPPVPTEGL--TPDDVPALADRVR 252
Cdd:cd07989 156 VTVRIGEPIPPEGLelAEEDRKELREKVR 184
PlsC COG0204
1-acyl-sn-glycerol-3-phosphate acyltransferase [Lipid transport and metabolism]; ...
 64-265 3.19e-57

1-acyl-sn-glycerol-3-phosphate acyltransferase [Lipid transport and metabolism]; 1-acyl-sn-glycerol-3-phosphate acyltransferase is part of the Pathway/BioSystem: Phospholipid biosynthesis


Pssm-ID: 439974 [Multi-domain]  Cd Length: 215  Bit Score: 182.90  E-value: 3.19e-57
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 47058950  64 KILRLLLLHVKYLYGIRVEVRGAQHFPPTQPYVVVSNHQSSLDLLGMMEVLPDRCVPIAKRELLWAGSAGLACWLAGVIF 143
Cdd:COG0204  14 RLVRLWARLLLRLLGVRVRVEGLENLPADGPVLIVANHQSWLDILLLLAALPRPVRFVAKKELFKIPLLGWLLRALGAIP 93

                        90       100       110       120       130       140       150       160
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 47058950 144 IDRKRTGDAISVMSEVAQtLLTQDVRVWVFPEGTRNHNGSMLPFKRGAFHLAVQAQVPIVPIVMSSYQDFYCKKeRRFTS 223
Cdd:COG0204  94 VDRSKRRAALRALRQAVE-ALKAGESLVIFPEGTRSPDGRLLPFKTGAARLALEAGVPIVPVAIDGTERALPKG-FLPRP 171

                       170       180       190       200
                ....*....|....*....|....*....|....*....|..
gi 47058950 224 GRCQVRVLPPVPTEGLTPDDVPALADRVRHSMLTIFREISTD 265
Cdd:COG0204 172 GKVTVRIGPPIDPSDLEGEDRRELAERLRAAIEALLAELRAE 213
Acyltransferase pfam01553
Acyltransferase; This family contains acyltransferases involved in phospholipid biosynthesis ...
 80-208 6.72e-44

Acyltransferase; This family contains acyltransferases involved in phospholipid biosynthesis and other proteins of unknown function. This family also includes tafazzin, the Barth syndrome gene.


Pssm-ID: 366704 [Multi-domain]  Cd Length: 131  Bit Score: 145.50  E-value: 6.72e-44
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 47058950    80 RVEVRGAQHFPPTQPYVVVSNHQSSLDLLGMMEVLPD---RCVPIAKRELLWAGSAGLACWLAGVIFIDRKRTGDAISVM 156
Cdd:pfam01553   1 RIEVHGLENLPRGGPAIVVANHQSYLDVLLLSLALYKrgrPLVFVAKKELFDIPLVGWLMRLLGCIFIDRKNRKDAAGTL 80

                          90       100       110       120       130
                  ....*....|....*....|....*....|....*....|....*....|..
gi 47058950   157 SEVAQtLLTQDVRVWVFPEGTRNHNGSMLPFKRGAFHLAVQAQVPIVPIVMS 208
Cdd:pfam01553  81 EYLVE-LLREGKLVVIFPEGTRSREGELLPFKKGAFRLAIEAGVPIVPVAIS 131
AGP_acyltrn TIGR00530
1-acyl-sn-glycerol-3-phosphate acyltransferases; This model describes the core homologous ...
 78-208 3.11e-41

1-acyl-sn-glycerol-3-phosphate acyltransferases; This model describes the core homologous region of a collection of related proteins, several of which are known to act as 1-acyl-sn-glycerol-3-phosphate acyltransferases (EC 2.3.1.51). Proteins scoring above the trusted cutoff are likely to have the same general activity. However, there is variation among characterized members as to whether the acyl group can be donated by acyl carrier protein or coenzyme A, and in the length and saturation of the donated acyl group. 1-acyl-sn-glycerol-3-phosphate acyltransferase is also called 1-AGP acyltransferase, lysophosphatidic acid acyltransferase, and LPA acyltransferase. [Fatty acid and phospholipid metabolism, Biosynthesis]


Pssm-ID: 129621 [Multi-domain]  Cd Length: 130  Bit Score: 138.63  E-value: 3.11e-41
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 47058950    78 GIRVEVRGAQHFPPTQPYVVVSNHQSSLDLLGMMEVLPDRCVPIAKRELLWAGSAGLACWLAGVIFIDRKRTgDAISVMS 157
Cdd:TIGR00530   1 GLKVEVVGPENLPAKSPVLVVANHQSNLDPLTLSAAFPPPIVFIAKKELKWIPFFGIMLWLTGAIFIDRENI-RAIATAL 79

                          90       100       110       120       130
                  ....*....|....*....|....*....|....*....|....*....|.
gi 47058950   158 EVAQTLLTQDVRVWVFPEGTRNHNGSMLPFKRGAFHLAVQAQVPIVPIVMS 208
Cdd:TIGR00530  80 KAAIEVLKQGRSIGVFPEGTRSRGRDILPFKKGAFHIAIKAGVPILPVVLS 130
PlsC smart00563
Phosphate acyltransferases; Function in phospholipid biosynthesis and have either ...
 95-208 5.82e-36

Phosphate acyltransferases; Function in phospholipid biosynthesis and have either glycerolphosphate, 1-acylglycerolphosphate, or 2-acylglycerolphosphoethanolamine acyltransferase activities. Tafazzin, the product of the gene mutated in patients with Barth syndrome, is a member of this family.


Pssm-ID: 214724 [Multi-domain]  Cd Length: 118  Bit Score: 124.77  E-value: 5.82e-36
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 47058950     95 YVVVSNHQSSLDLLGMMEVLPD---RCVPIAKRELLWAGSAGLACWLAGVIFIDRKRTGDAISVMSEVAQtLLTQDVRVW 171
Cdd:smart00563   1 ALVVANHQSFLDPLVLSALLPRklgRVRFVAKKELFYVPLLGWLLRLLGAIFIDRSNGRKARAALREAVE-LLKEGEWLL 79

                           90       100       110
                   ....*....|....*....|....*....|....*..
gi 47058950    172 VFPEGTRNHNGSMLPFKRGAFHLAVQAQVPIVPIVMS 208
Cdd:smart00563  80 IFPEGTRSRPGKLLPFKKGAARLALEAGVPIVPVAIR 116
PRK15018 PRK15018
1-acyl-sn-glycerol-3-phosphate acyltransferase; Provisional
 31-255 1.86e-28

1-acyl-sn-glycerol-3-phosphate acyltransferase; Provisional


Pssm-ID: 184979  Cd Length: 245  Bit Score: 109.33  E-value: 1.86e-28
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 47058950   31 YFFKMAFYNGWILFLAILAIPVCAVRGRNVENMKILRLLLLHVKYLYGIRVEVRGAQHFPPTQPYVVVSNHQSSLDLLGM 110
Cdd:PRK15018   3 YIFRLIITVIYSILVCVFGSIYCLFSPRNPKHVATFGHMFGRLAPLFGLKVECRKPADAESYGNAIYIANHQNNYDMVTA 82

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 47058950  111 MEVLPDRCVPIAKRELLWAGSAGLACWLAGVIFIDRKRTGDAISVMSEVAQTLLTQDVRVWVFPEGTRNHNGSMLPFKRG 190
Cdd:PRK15018  83 SNIVQPPTVTVGKKSLLWIPFFGQLYWLTGNLLIDRNNRTKAHGTIAEVVNHFKKRRISIWMFPEGTRSRGRGLLPFKTG 162

                        170       180       190       200       210       220
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 47058950  191 AFHLAVQAQVPIVPIVMSSYQDFYckKERRFTSGRCQVRVLPPVPTEGLTPDDVPALADRVRHSM 255
Cdd:PRK15018 163 AFHAAIAAGVPIIPVCVSTTSNKI--NLNRLHNGLVIVEMLPPIDVSQYGKDQVRELAAHCRSIM 225
LPLAT cd06551
Lysophospholipid acyltransferases (LPLATs) of glycerophospholipid biosynthesis; ...
 67-208 6.45e-20

Lysophospholipid acyltransferases (LPLATs) of glycerophospholipid biosynthesis; Lysophospholipid acyltransferase (LPLAT) superfamily members are acyltransferases of de novo and remodeling pathways of glycerophospholipid biosynthesis. These proteins catalyze the incorporation of an acyl group from either acylCoAs or acyl-acyl carrier proteins (acylACPs) into acceptors such as glycerol 3-phosphate, dihydroxyacetone phosphate or lyso-phosphatidic acid. Included in this superfamily are LPLATs such as glycerol-3-phosphate 1-acyltransferase (GPAT, PlsB), 1-acyl-sn-glycerol-3-phosphate acyltransferase (AGPAT, PlsC), lysophosphatidylcholine acyltransferase 1 (LPCAT-1), lysophosphatidylethanolamine acyltransferase (LPEAT, also known as, MBOAT2, membrane-bound O-acyltransferase domain-containing protein 2), lipid A biosynthesis lauroyl/myristoyl acyltransferase, 2-acylglycerol O-acyltransferase (MGAT), dihydroxyacetone phosphate acyltransferase (DHAPAT, also known as 1 glycerol-3-phosphate O-acyltransferase 1) and Tafazzin (the protein product of the Barth syndrome (TAZ) gene).


Pssm-ID: 153244 [Multi-domain]  Cd Length: 187  Bit Score: 84.77  E-value: 6.45e-20
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 47058950  67 RLLLLHvkYLYGIRVEVRGAQHFPPTQPYVVVSNHQSSLDLLgMMEVLPDRcvpIAKRELLWAGSA--GLACWL---AGV 141
Cdd:cd06551   2 RYLLLN--FFGFVRLEVKGPPPPPGGGPVLFVSNHSSWWDGL-ILFLLLER---GLRRDVYGLMDEelLERYPFftrLGA 75

                        90       100       110       120       130       140
                ....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 47058950 142 IFIDRKRTGDAISVMSEVAQTLLTQDVRVWVFPEGTRNHNGS-MLPFKRGAFHLAVQAQVPIVPIVMS 208
Cdd:cd06551  76 FSVDRDSPRSAAKSLKYVARLLSKPGSVVWIFPEGTRTRRDKrPLQFKPGVAHLAEKAGVPIVPVALR 143
PLN02901 PLN02901
1-acyl-sn-glycerol-3-phosphate acyltransferase
 80-252 1.25e-17

1-acyl-sn-glycerol-3-phosphate acyltransferase


Pssm-ID: 215488 [Multi-domain]  Cd Length: 214  Bit Score: 79.39  E-value: 1.25e-17
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 47058950   80 RVEVRGAQHFP-PTQPYVVVSNHQSSLDLLGMMEVlpDRCVP-IAKRELLWAGSAGLACWLAGVIFIdrKRTgDAISVMS 157
Cdd:PLN02901  36 KIEVEGLENLPsPDEPAVYVSNHQSFLDIYTLFHL--GRPFKfISKTSIFLIPIIGWAMYMTGHIPL--KRM-DRRSQLE 110

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 47058950  158 EVAQT--LLTQDVRVWVFPEGTRNHNGSMLPFKRGAFHLAVQAQVPIVPIV-MSSYQDFYCKKERRFTSGRCQVRVLPPV 234
Cdd:PLN02901 111 CLKRCmeLLKKGASVFFFPEGTRSKDGKLAAFKKGAFSVAAKTGVPVVPITlVGTGKIMPNGKEGILNPGSVKVVIHPPI 190

                        170
                 ....*....|....*...
gi 47058950  235 ptEGLTPDDvpaLADRVR 252
Cdd:PLN02901 191 --EGSDADE---LCNEAR 203
LPLAT_LPCAT1-like cd07991
Lysophospholipid Acyltransferases (LPLATs) of Glycerophospholipid Biosynthesis: LPCAT1-like; ...
 78-255 8.87e-15

Lysophospholipid Acyltransferases (LPLATs) of Glycerophospholipid Biosynthesis: LPCAT1-like; Lysophospholipid acyltransferase (LPLAT) superfamily member: acyltransferases of de novo and remodeling pathways of glycerophospholipid biosynthesis which catalyze the incorporation of an acyl group from either acylCoAs or acyl-acyl carrier proteins (acylACPs) into acceptors such as glycerol 3-phosphate, dihydroxyacetone phosphate or lyso-phosphatidic acid. Included in this subgroup are such LPLATs as lysophosphatidylcholine acyltransferase 1 (LPCAT-1), glycerol-3-phosphate acyltransferase 3 (GPAT3), and similar sequences.


Pssm-ID: 153253 [Multi-domain]  Cd Length: 211  Bit Score: 71.48  E-value: 8.87e-15
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 47058950  78 GIRVEVRGAQHfPPTQPYVVVSNHQSSLDLLGMMEVLPdrCVPIAKRELLWAGSAGLACWLAGVIFIDRKRTGDAISVMS 157
Cdd:cd07991  10 FYVIKVHGKPD-PPEAPRIIVANHTSFIDPLILFSDLF--PSIVAKKELGKLPFIGTILRALGCIFVDRSEPKDRKKVVE 86

                        90       100       110       120       130       140       150       160
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 47058950 158 EVAQTLLTQDVR-VWVFPEGTRNHNGSMLPFKRGAFhlavQAQVPIVPIVM----------------SSYQDFYckkeRR 220
Cdd:cd07991  87 EIKERATDPNWPpILIFPEGTTTNGKALIMFKKGAF----EPGVPVQPVAIrypnkfvdafwnssgySSLMYLF----RL 158

                       170       180       190
                ....*....|....*....|....*....|....*....
gi 47058950 221 FTS--GRCQVRVLPPV--PTEGLTPDdvpALADRVRHSM 255
Cdd:cd07991 159 LTQpaNVLEVEFLPVYtpSEEGEDPK---EFANRVRLIM 194
LPLAT_LCLAT1-like cd07990
Lysophospholipid Acyltransferases (LPLATs) of Glycerophospholipid Biosynthesis: LCLAT1-like; ...
 75-178 9.83e-13

Lysophospholipid Acyltransferases (LPLATs) of Glycerophospholipid Biosynthesis: LCLAT1-like; Lysophospholipid acyltransferase (LPLAT) superfamily member: acyltransferases of de novo and remodeling pathways of glycerophospholipid biosynthesis which catalyze the incorporation of an acyl group from either acylCoAs or acyl-acyl carrier proteins (acylACPs) into acceptors such as glycerol 3-phosphate, dihydroxyacetone phosphate or lyso-phosphatidic acid. Included in this subgroup are such LPLATs as Lysocardiolipin acyltransferase 1 (LCLAT1) or 1-acyl-sn-glycerol-3-phosphate acyltransferase and similar proteins.


Pssm-ID: 153252 [Multi-domain]  Cd Length: 193  Bit Score: 65.34  E-value: 9.83e-13
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 47058950  75 YLYGIRVEVRGAQHFPPTQPYVVVSNHQSSLD-LLGMMEVLPDRCVP----IAKRELLWAGSAGLACWLAGVIFIDRKRT 149
Cdd:cd07990   6 WLSGVKVVVYGDEPKLPKERALIISNHRSEVDwLVLWMLADRFGRLGrlkiVLKDSLKYPPLGGWGWQLGEFIFLKRKWE 85

                        90       100       110
                ....*....|....*....|....*....|.
gi 47058950 150 GDAIsVMSEVAQTLLTQDVRVWV--FPEGTR 178
Cdd:cd07990  86 KDEK-TIKRQLKRLKDSPEPFWLliFPEGTR 115
LPLAT_AAK14816-like cd07992
Lysophospholipid Acyltransferases (LPLATs) of Glycerophospholipid Biosynthesis: Unknown ...
 66-257 5.02e-10

Lysophospholipid Acyltransferases (LPLATs) of Glycerophospholipid Biosynthesis: Unknown AAK14816-like; Lysophospholipid acyltransferase (LPLAT) superfamily member: acyltransferases of de novo and remodeling pathways of glycerophospholipid biosynthesis which catalyze the incorporation of an acyl group from either acylCoAs or acyl-acyl carrier proteins (acylACPs) into acceptors such as glycerol 3-phosphate, dihydroxyacetone phosphate or lyso-phosphatidic acid. Included in this subgroup are uncharacterized glycerol-3-phosphate acyltransferases such as the Plasmodium falciparum locus AAK14816 putative acyltransferase, and similar proteins.


Pssm-ID: 153254 [Multi-domain]  Cd Length: 203  Bit Score: 58.04  E-value: 5.02e-10
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 47058950  66 LRLLLLHVKYLYGIRVEVRGAQHFPPTQPYVVVSNHQSSL-DLLGMMEVLPDRCVPIAKRELLWAGSAGLACWLAGVIFI 144
Cdd:cd07992   1 VRLLSRVILRIYFRRITVVGRENVPKDGPVIFLGNHPNALiDPLLLAATLRRPVRFLAKADLFKNPLIGWLLESFGAIPV 80

                        90       100       110       120       130       140       150       160
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 47058950 145 DRKR----TGDAIS----VMSEVAQTLLTQDvRVWVFPEGTrNHNGS-MLPFKRGAFHLAVQA------QVPIVPIVMss 209
Cdd:cd07992  81 YRPKdlarGGIGKIsnaaVFDAVGEALKAGG-AIGIFPEGG-SHDRPrLLPLKAGAARMALEAleagqkDVKIVPVGL-- 156

                       170       180       190       200
                ....*....|....*....|....*....|....*....|....*...
gi 47058950 210 yqdFYCKKErRFTSgRCQVRVLPPVPTEGLTPDDVPALADRVRHSMLT 257
Cdd:cd07992 157 ---NYEDKS-RFRS-RVLVEFGKPISVSAFEEAEASRDVEKKLINQLE 199
PRK08633 PRK08633
2-acyl-glycerophospho-ethanolamine acyltransferase; Validated
 42-204 2.47e-09

2-acyl-glycerophospho-ethanolamine acyltransferase; Validated


Pssm-ID: 236315 [Multi-domain]  Cd Length: 1146  Bit Score: 58.01  E-value: 2.47e-09
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 47058950    42 ILFLAILAIPVCAVRGRNVEN--MKILRLLLLHVKYlygiRVEVRGAQHFPPTQPYVVVSNHQSSLD--LLGMMEVLPDR 117
Cdd:PRK08633  392 FYLIALVTLIGTLYTLLLLPDslLRFLLLLLMHTRY----RLRVEGRENIPAKGGALLLGNHVSWIDwaLLQAASPRPIR 467

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 47058950   118 CV---PIAKRELLwagsaglaCWLA---GVIFIDRKRTGDAISVMSEvaqtLLTQDVRVWVFPEGTRNHNGSMLPFKRGa 191
Cdd:PRK08633  468 FVmerSIYEKWYL--------KWFFklfGVIPISSGGSKESLEFIRK----ALDDGEVVCIFPEGAITRNGQLNEFKRG- 534

                         170
                  ....*....|....
gi 47058950   192 FHLAVQ-AQVPIVP 204
Cdd:PRK08633  535 FELIVKgTDVPIIP 548
LPLAT_ABO13168-like cd07988
Lysophospholipid Acyltransferases (LPLATs) of Glycerophospholipid Biosynthesis: Unknown ...
 90-252 1.46e-07

Lysophospholipid Acyltransferases (LPLATs) of Glycerophospholipid Biosynthesis: Unknown ABO13168; Lysophospholipid acyltransferase (LPLAT) superfamily member: acyltransferases of de novo and remodeling pathways of glycerophospholipid biosynthesis which catalyze the incorporation of an acyl group from either acylCoAs or acyl-acyl carrier proteins (acylACPs) into acceptors such as glycerol 3-phosphate, dihydroxyacetone phosphate or lyso-phosphatidic acid. Included in this subgroup are uncharacterized phospholipid/glycerol acyltransferases such as the Acinetobacter baumannii ATCC 17978 locus ABO13168 putative acyltransferase, and similar proteins.


Pssm-ID: 153250 [Multi-domain]  Cd Length: 163  Bit Score: 49.91  E-value: 1.46e-07
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 47058950  90 PPTQP-YVV-VSNHQSSLDLLGMMEVLPDRCVPI---AKRELLWAGSAGLACWLaGVIFIDRKRTGDAISVMSEVAQTll 164
Cdd:cd07988  16 PPNKPkFVViGAPHTSNWDFVLGLLAAFALGLKIsflGKHSLFKPPLGPFMRWL-GGIPVDRSRAGGLVEQVVEEFRR-- 92

                        90       100       110       120       130       140       150       160
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 47058950 165 tQDVRVWVF-PEGTRNHNGsmlPFKRGAFHLAVQAQVPIVPivmsSYQDFYCKkerrftsgrcQVRVLPPVPTEGLTPDD 243
Cdd:cd07988  93 -REEFVLAIaPEGTRSKVD---KWKTGFYHIARGAGVPILL----VYLDYKRK----------TVGIGPLFEPSGDIEAD 154


                ....*....
gi 47058950 244 VPALADRVR 252
Cdd:cd07988 155 LAAIRAFYR 163
LPLAT_DHAPAT-like cd07993
Lysophospholipid Acyltransferases (LPLATs) of Glycerophospholipid Biosynthesis: GPAT-like; ...
 139-229 3.96e-07

Lysophospholipid Acyltransferases (LPLATs) of Glycerophospholipid Biosynthesis: GPAT-like; Lysophospholipid acyltransferase (LPLAT) superfamily member: acyltransferases of de novo and remodeling pathways of glycerophospholipid biosynthesis which catalyze the incorporation of an acyl group from either acylCoAs or acyl-acyl carrier proteins (acylACPs) into acceptors such as glycerol 3-phosphate, dihydroxyacetone phosphate or lyso-phosphatidic acid. Included in this subgroup are such LPLATs as dihydroxyacetone phosphate acyltransferase (DHAPAT, also known as 1 glycerol-3-phosphate O-acyltransferase 1) and similar proteins.


Pssm-ID: 153255 [Multi-domain]  Cd Length: 205  Bit Score: 49.49  E-value: 3.96e-07
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 47058950 139 AGVIFIDRKRTGDAI--SVMSEVAQTLLTQDVRVWVFPEGTRNHNGSMLPFKRG-------AFHLAVQAQVPIVPIVMsS 209
Cdd:cd07993  71 LGAFFIRRSFGKDPLyrAVLQEYVQELLKNGQPLEFFIEGTRSRTGKLLPPKLGllsvvveAYLKGSVPDVLIVPVSI-S 149

                        90       100       110
                ....*....|....*....|....*....|.
gi 47058950 210 Y-----QDFYC------KKERRFTSGRCQVR 229
Cdd:cd07993 150 YdrvleEELYAeellgpPKPKESLSGLLGAS 180
PRK14014 PRK14014
putative acyltransferase; Provisional
 74-146 4.61e-07

putative acyltransferase; Provisional


Pssm-ID: 237584 [Multi-domain]  Cd Length: 301  Bit Score: 50.24  E-value: 4.61e-07
                         10        20        30        40        50        60        70
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 47058950   74 KYLYGIRVEVRGAQHFPPTQPYVVVSNHQSSLDLLGMMEVLPDRcVPI----AKRELLWAGSAGLACWLAGVIFIDR 146
Cdd:PRK14014  68 RLLPRTQWDVEGLEGLSKKGWYLVISNHQSWVDILVLQYVFNRR-IPMlkffLKQELIWVPFLGLAWWALDFPFMKR 143
PRK06814 PRK06814
acyl-[ACP]--phospholipid O-acyltransferase;
33-254 3.81e-06

acyl-[ACP]--phospholipid O-acyltransferase;


Pssm-ID: 235865 [Multi-domain]  Cd Length: 1140  Bit Score: 48.04  E-value: 3.81e-06
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 47058950    33 FKMAFYNGWILFL-----AILAIPVCAVRGRNVenMK-ILRLLLlhvKYLYgiRVEVRGAQHFPPTQP-YVVVSNHQSSL 105
Cdd:PRK06814  394 QALGFSIPWIILFialanLIVAILILRLLPTNL--LRdIFSILF---RAFY--RVEVKGLENLQKAGKkAVIAANHVSFL 466

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 47058950   106 DLLGMMEVLPDRCV-----PIAKRellWagsaglacWLAGVIFIDRKRTGDAISVMSevAQTL---LTQDVRVWVFPEGT 177
Cdd:PRK06814  467 DGPLLAAYLPEEPTfaidtDIAKA---W--------WVKPFLKLAKALPVDPTNPMA--TRTLikeVQKGEKLVIFPEGR 533

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 47058950   178 RNHNGSMLPFKRGAFHLAVQAQVPIVPIVMSSYQDFYC----KKERRFTSGRCQVRVLPPVpteglTPDDVPALADRVRH 253
Cdd:PRK06814  534 ITVTGSLMKIYDGPGMIADKAGAMVVPVRIDGLQFTHFsrlkNQVRRKWFPKVTVTILPPV-----KLAVDPELKGRERR 608


                  .
gi 47058950   254 S 254
Cdd:PRK06814  609 S 609
LPLAT_ACT14924-like cd07986
Lysophospholipid Acyltransferases (LPLATs) of Glycerophospholipid Biosynthesis: Unknown ...
 79-205 4.53e-06

Lysophospholipid Acyltransferases (LPLATs) of Glycerophospholipid Biosynthesis: Unknown ACT14924; Lysophospholipid acyltransferase (LPLAT) superfamily member: acyltransferases of de novo and remodeling pathways of glycerophospholipid biosynthesis which catalyze the incorporation of an acyl group from either acylCoAs or acyl-acyl carrier proteins (acylACPs) into acceptors such as glycerol 3-phosphate, dihydroxyacetone phosphate or lyso-phosphatidic acid. Included in this subgroup are uncharacterized phospholipid/glycerol acyltransferases such as the Pectobacterium carotovorum subsp. carotovorum PC1 locus ACT14924 putative acyltransferase, and similar proteins.


Pssm-ID: 153248 [Multi-domain]  Cd Length: 210  Bit Score: 46.47  E-value: 4.53e-06
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 47058950  79 IRVEVRGAQHFPPTQPYVVVSNHQ-SSLDLLGMMEVL----PDrcVPIAKRELLWAGSAgLACWLAGVIFIDRKRTGD-A 152
Cdd:cd07986   8 LEVDVSGLENIPKDGPVVIVANHPfGILDGLILADLLgsvrPD--VRILANQLLSKIPE-LRDLFIPVDPLEGRAALAkN 84

                        90       100       110       120       130
                ....*....|....*....|....*....|....*....|....*....|....*....
gi 47058950 153 ISVMSEvAQTLLTQDVRVWVFPEGT-----RNHNGSM-LPFKRGAFHLAVQAQVPIVPI 205
Cdd:cd07986  85 RESLRE-ALRHLKNGGALIIFPAGRvstasPPFGRVSdRPWNPFVARLARKAKAPVVPV 142
LPLAT_MGAT-like cd07987
Lysophospholipid Acyltransferases (LPLATs) of Glycerophospholipid Biosynthesis: MGAT-like; ...
 82-204 2.72e-04

Lysophospholipid Acyltransferases (LPLATs) of Glycerophospholipid Biosynthesis: MGAT-like; Lysophospholipid acyltransferase (LPLAT) superfamily member: acyltransferases of de novo and remodeling pathways of glycerophospholipid biosynthesis which catalyze the incorporation of an acyl group from either acylCoAs or acyl-acyl carrier proteins (acylACPs) into acceptors such as glycerol 3-phosphate, dihydroxyacetone phosphate or lyso-phosphatidic acid. Included in this suubgroup are such LPLATs as 2-acylglycerol O-acyltransferase (MGAT), and similar proteins.


Pssm-ID: 153249 [Multi-domain]  Cd Length: 212  Bit Score: 41.12  E-value: 2.72e-04
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 47058950  82 EVRGAQHFPPTQPYVVVSNHqssldllGMMevLPDRCVPIAKRELLWAGsagLACWLAGVIFI-------DRKRTGDAIS 154
Cdd:cd07987   9 EVRGLENIPDEGPALLVHPH-------GGL--PIDGALLAAAFLLLFPG---RLPRALADHFLfplpglrDLLRRLGAVP 76

                        90       100       110       120       130
                ....*....|....*....|....*....|....*....|....*....|....*..
gi 47058950 155 VMSEVAQTLLTQDVRVWVFPEGTR-------NHNGSMLPFKRGAFHLAVQAQVPIVP 204
Cdd:cd07987  77 GSRENCVRLLREGELVLIFPGGARealkskrEEYYLLWKKRKGFARLALRAGAPIVP 133
PLN02833 PLN02833
glycerol acyltransferase family protein
 22-252 4.92e-03

glycerol acyltransferase family protein


Pssm-ID: 215447  Cd Length: 376  Bit Score: 37.83  E-value: 4.92e-03
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 47058950   22 LWFCSSSAKYF--FKMAF---YNGWILFLAiLAIPVCAVRGRNVENMKILRLLLLH------------VKYlYGIRVEVR 84
Cdd:PLN02833  85 LWCVGVVIRYGilFPVRVlllAIGWIIFLS-AFIPVHFLLKGHKLRKKIERKLVELicsafvaswtgvIKY-HGPRPSRR 162

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 47058950   85 GAQhfpptqpyVVVSNHQSSLDLLGMMEVLPdrCVPIAKRELLWAG---SAGLACwlAGVIFIDRKRTGDaisvmSEVAQ 161
Cdd:PLN02833 163 PKQ--------VFVANHTSMIDFIVLEQMTP--FAVIMQKHPGWVGflqNTILES--VGCIWFNRTEAKD-----REVVA 225

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 47058950  162 TLLTQDVR------VWVFPEGTRNHNGSMLPFKRGAFHLAVQaqvpIVPIVM------------SSYQDFYCKKERRFTS 223
Cdd:PLN02833 226 KKLRDHVQdpdrnpLLIFPEGTCVNNEYTVMFKKGAFELGCT----VCPIAIkynkifvdafwnSRKQSFTMHLLRLMTS 301

                        250       260       270
                 ....*....|....*....|....*....|..
gi 47058950  224 GR--CQVRVLPPvptEGLTPDDVP-ALADRVR 252
Cdd:PLN02833 302 WAvvCDVWYLEP---QTLRPGETPiEFAERVR 330
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
Help | Disclaimer | Write to the Help Desk
NCBI | NLM | NIH