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Conserved domains on  [gi|861483604|ref|XP_004863367|]
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nuclear mitotic apparatus protein 1 isoform X3 [Heterocephalus glaber]

Protein Classification

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
HkD_NuMA cd22224
Hook domain found in nuclear mitotic apparatus protein (NuMA) and similar proteins; NuMA, also ...
 6-152 2.51e-50

Hook domain found in nuclear mitotic apparatus protein (NuMA) and similar proteins; NuMA, also called nuclear mitotic apparatus protein 1, or nuclear matrix protein-22 (NMP-22), or SP-H antigen, is a microtubule (MT)-binding protein that plays a role in the formation and maintenance of the spindle poles, and the alignment and segregation of chromosomes during mitotic cell division. The model corresponds to the N-terminal conserved globular Hook domain of NuMA, which folds as a variant of the helical calponin homology (CH) domain. It directly binds dynein light intermediate chains LIC1 and LIC2 through a conserved hydrophobic patch shared among other Hook adaptors.


:

Pssm-ID: 411795  Cd Length: 148  Bit Score: 175.07  E-value: 2.51e-50
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 861483604    6 TRAAALLSWVNSLRVADLVEAVPQLQDCSVFIKIIDGIRGTEEGQQILQQPVPERLDFVCSFLQKNRKRPSSPECLVSMQ 85
Cdd:cd22224     2 TKAEALLSWVNSLKLDDPIESISQLQDGTILLKIIYKLKGEEEEEQILDLSVEERLEFISSFLEGDCRFNSSQGTLVSWQ 81

                          90       100       110       120       130       140
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 861483604   86 KVMEG--SELELAKIIMLLLYHSSMSsqNLRDWEQFEYRIQAELAVILKFMLDHEDGLNLTEDLEIFLQ 152
Cdd:cd22224    82 KILQGenLELELAKVLLLLLYHSMMN--NNLTLEKLDYKTELELASILRFVLDNEDGLYLSEGLDKFLT 148
NuMA_LGNBD cd22298
LGN binding domain (LGNBD) of nuclear mitotic apparatus protein (NuMA) and similar proteins; ...
 1872-1930 3.49e-27

LGN binding domain (LGNBD) of nuclear mitotic apparatus protein (NuMA) and similar proteins; NuMA, also called nuclear matrix protein-22 (NMP-22), nuclear mitotic apparatus protein 1 (NUMA1), or SP-H antigen, is a microtubule (MT)-binding protein that plays a role in the formation and maintenance of spindle poles and the alignment and segregation of chromosomes during mitotic cell division. It is involved in the establishment of mitotic spindle orientation during metaphase, and elongation during anaphase in a dynein-dynactin-dependent manner. NuMA, in complex with LGN, forms NuMA:LGN hetero-hexamers that promote spindle orientation. The model corresponds to the LGN binding domain (LGNBD) of NuMA. LGN (named for leu-gly-asn repeats) is also known as G protein signaling modulator 2.


:

Pssm-ID: 412093  Cd Length: 56  Bit Score: 105.76  E-value: 3.49e-27
                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|....*....
gi 861483604 1872 LLSLPGYRPTTRSSTRRSQagvSSGAPPGRNSFYMGTCQDEPEQLDDWNRIAELQQRNR 1930
Cdd:cd22298     1 LLSLPGYRPSTRSSTRRSQ---SSSATGGRSTFYMGTCQDEPEHLDDWNRIAELQQRNR 56
SMC_prok_B super family cl37069
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...
 553-1329 2.53e-23

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


The actual alignment was detected with superfamily member TIGR02168:

Pssm-ID: 274008 [Multi-domain]  Cd Length: 1179  Bit Score: 108.61  E-value: 2.53e-23
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 861483604   553 VEQLSGSLKQKEKQLEEA--ARELDASRRDHAQQLATA-AKAQETSLRERDAACQQLEALEKEKAAKLEILQQQLQAANE 629
Cdd:TIGR02168  195 LNELERQLKSLERQAEKAerYKELKAELRELELALLVLrLEELREELEELQEELKEAEEELEELTAELQELEEKLEELRL 274

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 861483604   630 AQDSAQNSVTQAQREKAELSQKVEELHALIEAAHQEQCEAQTQVAALEARLKAEQQKateREKVAQEKAQLQEQLWSLEE 709
Cdd:TIGR02168  275 EVSELEEEIEELQKELYALANEISRLEQQKQILRERLANLERQLEELEAQLEELESK---LDELAEELAELEEKLEELKE 351

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 861483604   710 SLKITKGSLEEEKCRAAAA---LEEHQHHISEMEAESRSLAEQHKQERKELEEekakrrgLGVQLQQLAEtHQAETKALR 786
Cdd:TIGR02168  352 ELESLEAELEELEAELEELesrLEELEEQLETLRSKVAQLELQIASLNNEIER-------LEARLERLED-RRERLQQEI 423

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 861483604   787 QELAKARTSNNMAE--REVELLVKEVKTWRKRYEDsqqgetqygLQEQLTTLKEEYEKSCQELRETKEKMAgieahselQ 864
Cdd:TIGR02168  424 EELLKKLEEAELKElqAELEELEEELEELQEELER---------LEEALEELREELEEAEQALDAAERELA--------Q 486

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 861483604   865 IGQHQSELAQLHANLARALQQVQEKENRAQKLADDLSTLQEKMAATSKEVARLEALVRKA-------GEQQETASLELLK 937
Cdd:TIGR02168  487 LQARLDSLERLQENLEGFSEGVKALLKNQSGLSGILGVLSELISVDEGYEAAIEAALGGRlqavvveNLNAAKKAIAFLK 566

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 861483604   938 EPPKTRDRESEwVEEQQGQQLCSTQAALRAMEREAEQMGTELEKLRAALmesqgqqqeergqQEREVARLTQERGQAEAD 1017
Cdd:TIGR02168  567 QNELGRVTFLP-LDSIKGTEIQGNDREILKNIEGFLGVAKDLVKFDPKL-------------RKALSYLLGGVLVVDDLD 632

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 861483604  1018 LALEKAAKAELEMRL----------QNALNEQQAEFANLQEALSRALSEKEgkdQELSKLCEQEAVQRMELKELLQTVEQ 1087
Cdd:TIGR02168  633 NALELAKKLRPGYRIvtldgdlvrpGGVITGGSAKTNSSILERRREIEELE---EKIEELEEKIAELEKALAELRKELEE 709

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 861483604  1088 LKAQLAKKEKEQQQSARGASGENASgmgtQSEAVGKMEALRAKVSKLEQQCQQQQEEADSLARSLESERAFHVERDRALE 1167
Cdd:TIGR02168  710 LEEELEQLRKELEELSRQISALRKD----LARLEAEVEQLEERIAQLSKELTELEAEIEELEERLEEAEEELAEAEAEIE 785

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 861483604  1168 TLQGQLEEKARELGYSQAASASAQRELATLRAKAQDHSKAEEEWKAQVARGQQEAVRKGSLISSLEEEVSILNRQVLEKE 1247
Cdd:TIGR02168  786 ELEAQIEQLKEELKALREALDELRAELTLLNEEAANLRERLESLERRIAATERRLEDLEEQIEELSEDIESLAAEIEELE 865

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 861483604  1248 GESKELKRLVIAESEKSQKLEERLRLL--QMETASNSARAAE-RSSALREEVQSLREEVEKQRAASENLRQELASQAERA 1324
Cdd:TIGR02168  866 ELIEELESELEALLNERASLEEALALLrsELEELSEELRELEsKRSELRRELEELREKLAQLELRLEGLEVRIDNLQERL 945


                   ....*
gi 861483604  1325 EELGQ 1329
Cdd:TIGR02168  946 SEEYS 950
PTZ00121 super family cl31754
MAEBL; Provisional
 1006-1724 2.26e-21

MAEBL; Provisional


The actual alignment was detected with superfamily member PTZ00121:

Pssm-ID: 173412 [Multi-domain]  Cd Length: 2084  Bit Score: 102.53  E-value: 2.26e-21
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 861483604 1006 RLTQERGQAEADLALEKAAKAELEMRLQNALNEQQAEFANLQEALSRALSEKEGKDQELSKLCEQ----EAVQRME---- 1077
Cdd:PTZ00121 1110 KAEEARKAEEAKKKAEDARKAEEARKAEDARKAEEARKAEDAKRVEIARKAEDARKAEEARKAEDakkaEAARKAEevrk 1189

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 861483604 1078 LKELLQTVEQLKAQLAKKEKEQQ--QSARGASGENASGMGTQSEAVGKMEALRAKVSKLEQQCQQQQEEADSLARSLESE 1155
Cdd:PTZ00121 1190 AEELRKAEDARKAEAARKAEEERkaEEARKAEDAKKAEAVKKAEEAKKDAEEAKKAEEERNNEEIRKFEEARMAHFARRQ 1269

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 861483604 1156 RAFHVERDRALETLQGQLEEKARElgysQAASASAQRELATLRAKAQDHSKAEE-EWKAQVARGQQEAVRKGSLISSLEE 1234
Cdd:PTZ00121 1270 AAIKAEEARKADELKKAEEKKKAD----EAKKAEEKKKADEAKKKAEEAKKADEaKKKAEEAKKKADAAKKKAEEAKKAA 1345

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 861483604 1235 EVSILNRQVLEKEGESKELKrlviAESEKSQKLEERLRLLQMETASNSARAAERSSALREEVQSLREEVEKQRAASEnlr 1314
Cdd:PTZ00121 1346 EAAKAEAEAAADEAEAAEEK----AEAAEKKKEEAKKKADAAKKKAEEKKKADEAKKKAEEDKKKADELKKAAAAKK--- 1418

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 861483604 1315 qelasQAERAEELGQELKAWQEKFFQKEQALSALQLEHTSTQALVSELLP--AKHLCQQLQAEQVAAEKRHREELEQSKQ 1392
Cdd:PTZ00121 1419 -----KADEAKKKAEEKKKADEAKKKAEEAKKADEAKKKAEEAKKAEEAKkkAEEAKKADEAKKKAEEAKKADEAKKKAE 1493

                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 861483604 1393 AAGGLRTELMRAQRELGELVPLRQkvAEQERAAQQLR-AEKASYAEQLsmlKKAHGLLAEENRGLGERANLGRQFLEVEl 1471
Cdd:PTZ00121 1494 EAKKKADEAKKAAEAKKKADEAKK--AEEAKKADEAKkAEEAKKADEA---KKAEEKKKADELKKAEELKKAEEKKKAE- 1567

                         490       500       510       520       530       540       550       560
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 861483604 1472 dQAREKYIQELAAVRGDAETRLAEMR--QEVQSTTHELEVMTA----KYEGAKVKVlEERQRFQEERQKltaqVEQLEVF 1545
Cdd:PTZ00121 1568 -EAKKAEEDKNMALRKAEEAKKAEEAriEEVMKLYEEEKKMKAeeakKAEEAKIKA-EELKKAEEEKKK----VEQLKKK 1641

                         570       580       590       600       610       620       630       640
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 861483604 1546 QREQTKKVEELSKKladyDQASKVQQQKLKafqaqggesqQEAQRLQTQLNELQVQLSQKEQAAEHYKVQMEKAKTHYDA 1625
Cdd:PTZ00121 1642 EAEEKKKAEELKKA----EEENKIKAAEEA----------KKAEEDKKKAEEAKKAEEDEKKAAEALKKEAEEAKKAEEL 1707

                         650       660       670       680       690       700       710       720
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 861483604 1626 KKQQNQELQEQlqglEQLQKENKELRAEAERLGQELQQAGLKTKEA--EQTCRHLTAQVRSLEAQVAHADQQLRElgkfQ 1703
Cdd:PTZ00121 1708 KKKEAEEKKKA----EELKKAEEENKIKAEEAKKEAEEDKKKAEEAkkDEEEKKKIAHLKKEEEKKAEEIRKEKE----A 1779

                         730       740
                  ....*....|....*....|.
gi 861483604 1704 VASDALKSREPQAKPQLDLSI 1724
Cdd:PTZ00121 1780 VIEEELDEEDEKRRMEVDKKI 1800
Smc super family cl34174
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ...
 215-811 1.73e-19

Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];


The actual alignment was detected with superfamily member COG1196:

Pssm-ID: 440809 [Multi-domain]  Cd Length: 983  Bit Score: 96.16  E-value: 1.73e-19
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 861483604  215 QMRRLKKQ---------LADERNNRDeLELELAEHRKLLTEKDAQISMMQQRIDRLALLNEKQAAspLEpRELEELRGKN 285
Cdd:COG1196   201 QLEPLERQaekaeryreLKEELKELE-AELLLLKLRELEAELEELEAELEELEAELEELEAELAE--LE-AELEELRLEL 276

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 861483604  286 ESLTFRLHETLKQCQDLKTEKGQMDRKINQLSEEngdlsfklrefasnLQQLQGALNELTEEHskatQQWVEKQAHLEKE 365
Cdd:COG1196   277 EELELELEEAQAEEYELLAELARLEQDIARLEER--------------RRELEERLEELEEEL----AELEEELEELEEE 338

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 861483604  366 LSTALQDKKCLEEKNEILQGKLSQLEERLAQLPESPRQEKGEVLGDVLQLESLKQEAATLATNNTQLQARVEMLENEQGQ 445
Cdd:COG1196   339 LEELEEELEEAEEELEEAEAELAEAEEALLEAEAELAEAEEELEELAEELLEALRAAAELAAQLEELEEAEEALLERLER 418

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 861483604  446 KEAQLLGERSHFEEEKQQLASLITNLQSSISNLSQAKEELEQASQAQGAKLNAQVASLTAELTTLSATLQQQDQELAGLK 525
Cdd:COG1196   419 LEEELEELEEALAELEEEEEEEEEALEEAAEEEAELEEEEEALLELLAELLEEAALLEAALAELLEELAEAAARLLLLLE 498

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 861483604  526 QQAQKKQAQLAQSLQQQEQASQGLRHQVEQLSGSLKQKEKQLEEAareLDASRRDHAQQLATAAKAQETSLRERDAACQQ 605
Cdd:COG1196   499 AEADYEGFLEGVKAALLLAGLRGLAGAVAVLIGVEAAYEAALEAA---LAAALQNIVVEDDEVAAAAIEYLKAAKAGRAT 575

                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 861483604  606 LEALEKEKAAKLEILQQQLQAANEAQDSAqnsvtQAQREKAELSQKVEELHALIEAAHQEQCEAQTQVAALEARLKAEQQ 685
Cdd:COG1196   576 FLPLDKIRARAALAAALARGAIGAAVDLV-----ASDLREADARYYVLGDTLLGRTLVAARLEAALRRAVTLAGRLREVT 650

                         490       500       510       520       530       540       550       560
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 861483604  686 KATEREKVAQEKAQLQEQlwSLEESLKITKGSLEEEKCRAAAALEEHQHHISEMEAESRSLAEQHKQERKELEEEKAKRR 765
Cdd:COG1196   651 LEGEGGSAGGSLTGGSRR--ELLAALLEAEAELEELAERLAEEELELEEALLAEEEEERELAEAEEERLEEELEEEALEE 728

                         570       580       590       600
                  ....*....|....*....|....*....|....*....|....*....
gi 861483604  766 GLGVQLQQLAETHQAETKALRQELAKARTSN---NMAEREVELLVKEVK 811
Cdd:COG1196   729 QLEAEREELLEELLEEEELLEEEALEELPEPpdlEELERELERLEREIE 777
PHA03307 super family cl33723
transcriptional regulator ICP4; Provisional
 1748-2003 2.23e-04

transcriptional regulator ICP4; Provisional


The actual alignment was detected with superfamily member PHA03307:

Pssm-ID: 223039 [Multi-domain]  Cd Length: 1352  Bit Score: 46.70  E-value: 2.23e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 861483604 1748 PDGTSVPGEPASPISQRlPPKVESLESLYFTPIPARGPA--PLESSLDSLGEPFLDSGRKTRSA-------------RRR 1812
Cdd:PHA03307  192 EPPPSTPPAAASPRPPR-RSSPISASASSPAPAPGRSAAddAGASSSDSSSSESSGCGWGPENEcplprpapitlptRIW 270

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 861483604 1813 TTQIINITMTKKLDVEEPDSANSSfYSTRSAPASQAGLRATSSTQSLARLGSPDDGNSAllslpgyrpTTRSSTRRSQAG 1892
Cdd:PHA03307  271 EASGWNGPSSRPGPASSSSSPRER-SPSPSPSSPGSGPAPSSPRASSSSSSSRESSSSS---------TSSSSESSRGAA 340

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 861483604 1893 VSSGAPPGRNsfymGTCQDEPeqldDWNRIAELQQRnrvCPPHLKTCYPLESRPSlglatitdeemktgdpqETLRRASM 1972
Cdd:PHA03307  341 VSPGPSPSRS----PSPSRPP----PPADPSSPRKR---PRPSRAPSSPAASAGR-----------------PTRRRARA 392

                         250       260       270
                  ....*....|....*....|....*....|....
gi 861483604 1973 Q---PGQIAEGAGITTRQQRKRVSSETHQGPGTP 2003
Cdd:PHA03307  393 AvagRARRRDATGRFPAGRPRPSPLDAGAASGAF 426
 
Name Accession Description Interval E-value
HkD_NuMA cd22224
Hook domain found in nuclear mitotic apparatus protein (NuMA) and similar proteins; NuMA, also ...
 6-152 2.51e-50

Hook domain found in nuclear mitotic apparatus protein (NuMA) and similar proteins; NuMA, also called nuclear mitotic apparatus protein 1, or nuclear matrix protein-22 (NMP-22), or SP-H antigen, is a microtubule (MT)-binding protein that plays a role in the formation and maintenance of the spindle poles, and the alignment and segregation of chromosomes during mitotic cell division. The model corresponds to the N-terminal conserved globular Hook domain of NuMA, which folds as a variant of the helical calponin homology (CH) domain. It directly binds dynein light intermediate chains LIC1 and LIC2 through a conserved hydrophobic patch shared among other Hook adaptors.


Pssm-ID: 411795  Cd Length: 148  Bit Score: 175.07  E-value: 2.51e-50
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 861483604    6 TRAAALLSWVNSLRVADLVEAVPQLQDCSVFIKIIDGIRGTEEGQQILQQPVPERLDFVCSFLQKNRKRPSSPECLVSMQ 85
Cdd:cd22224     2 TKAEALLSWVNSLKLDDPIESISQLQDGTILLKIIYKLKGEEEEEQILDLSVEERLEFISSFLEGDCRFNSSQGTLVSWQ 81

                          90       100       110       120       130       140
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 861483604   86 KVMEG--SELELAKIIMLLLYHSSMSsqNLRDWEQFEYRIQAELAVILKFMLDHEDGLNLTEDLEIFLQ 152
Cdd:cd22224    82 KILQGenLELELAKVLLLLLYHSMMN--NNLTLEKLDYKTELELASILRFVLDNEDGLYLSEGLDKFLT 148
NuMA_LGNBD cd22298
LGN binding domain (LGNBD) of nuclear mitotic apparatus protein (NuMA) and similar proteins; ...
 1872-1930 3.49e-27

LGN binding domain (LGNBD) of nuclear mitotic apparatus protein (NuMA) and similar proteins; NuMA, also called nuclear matrix protein-22 (NMP-22), nuclear mitotic apparatus protein 1 (NUMA1), or SP-H antigen, is a microtubule (MT)-binding protein that plays a role in the formation and maintenance of spindle poles and the alignment and segregation of chromosomes during mitotic cell division. It is involved in the establishment of mitotic spindle orientation during metaphase, and elongation during anaphase in a dynein-dynactin-dependent manner. NuMA, in complex with LGN, forms NuMA:LGN hetero-hexamers that promote spindle orientation. The model corresponds to the LGN binding domain (LGNBD) of NuMA. LGN (named for leu-gly-asn repeats) is also known as G protein signaling modulator 2.


Pssm-ID: 412093  Cd Length: 56  Bit Score: 105.76  E-value: 3.49e-27
                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|....*....
gi 861483604 1872 LLSLPGYRPTTRSSTRRSQagvSSGAPPGRNSFYMGTCQDEPEQLDDWNRIAELQQRNR 1930
Cdd:cd22298     1 LLSLPGYRPSTRSSTRRSQ---SSSATGGRSTFYMGTCQDEPEHLDDWNRIAELQQRNR 56
SMC_prok_B TIGR02168
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...
 553-1329 2.53e-23

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274008 [Multi-domain]  Cd Length: 1179  Bit Score: 108.61  E-value: 2.53e-23
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 861483604   553 VEQLSGSLKQKEKQLEEA--ARELDASRRDHAQQLATA-AKAQETSLRERDAACQQLEALEKEKAAKLEILQQQLQAANE 629
Cdd:TIGR02168  195 LNELERQLKSLERQAEKAerYKELKAELRELELALLVLrLEELREELEELQEELKEAEEELEELTAELQELEEKLEELRL 274

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 861483604   630 AQDSAQNSVTQAQREKAELSQKVEELHALIEAAHQEQCEAQTQVAALEARLKAEQQKateREKVAQEKAQLQEQLWSLEE 709
Cdd:TIGR02168  275 EVSELEEEIEELQKELYALANEISRLEQQKQILRERLANLERQLEELEAQLEELESK---LDELAEELAELEEKLEELKE 351

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 861483604   710 SLKITKGSLEEEKCRAAAA---LEEHQHHISEMEAESRSLAEQHKQERKELEEekakrrgLGVQLQQLAEtHQAETKALR 786
Cdd:TIGR02168  352 ELESLEAELEELEAELEELesrLEELEEQLETLRSKVAQLELQIASLNNEIER-------LEARLERLED-RRERLQQEI 423

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 861483604   787 QELAKARTSNNMAE--REVELLVKEVKTWRKRYEDsqqgetqygLQEQLTTLKEEYEKSCQELRETKEKMAgieahselQ 864
Cdd:TIGR02168  424 EELLKKLEEAELKElqAELEELEEELEELQEELER---------LEEALEELREELEEAEQALDAAERELA--------Q 486

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 861483604   865 IGQHQSELAQLHANLARALQQVQEKENRAQKLADDLSTLQEKMAATSKEVARLEALVRKA-------GEQQETASLELLK 937
Cdd:TIGR02168  487 LQARLDSLERLQENLEGFSEGVKALLKNQSGLSGILGVLSELISVDEGYEAAIEAALGGRlqavvveNLNAAKKAIAFLK 566

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 861483604   938 EPPKTRDRESEwVEEQQGQQLCSTQAALRAMEREAEQMGTELEKLRAALmesqgqqqeergqQEREVARLTQERGQAEAD 1017
Cdd:TIGR02168  567 QNELGRVTFLP-LDSIKGTEIQGNDREILKNIEGFLGVAKDLVKFDPKL-------------RKALSYLLGGVLVVDDLD 632

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 861483604  1018 LALEKAAKAELEMRL----------QNALNEQQAEFANLQEALSRALSEKEgkdQELSKLCEQEAVQRMELKELLQTVEQ 1087
Cdd:TIGR02168  633 NALELAKKLRPGYRIvtldgdlvrpGGVITGGSAKTNSSILERRREIEELE---EKIEELEEKIAELEKALAELRKELEE 709

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 861483604  1088 LKAQLAKKEKEQQQSARGASGENASgmgtQSEAVGKMEALRAKVSKLEQQCQQQQEEADSLARSLESERAFHVERDRALE 1167
Cdd:TIGR02168  710 LEEELEQLRKELEELSRQISALRKD----LARLEAEVEQLEERIAQLSKELTELEAEIEELEERLEEAEEELAEAEAEIE 785

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 861483604  1168 TLQGQLEEKARELGYSQAASASAQRELATLRAKAQDHSKAEEEWKAQVARGQQEAVRKGSLISSLEEEVSILNRQVLEKE 1247
Cdd:TIGR02168  786 ELEAQIEQLKEELKALREALDELRAELTLLNEEAANLRERLESLERRIAATERRLEDLEEQIEELSEDIESLAAEIEELE 865

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 861483604  1248 GESKELKRLVIAESEKSQKLEERLRLL--QMETASNSARAAE-RSSALREEVQSLREEVEKQRAASENLRQELASQAERA 1324
Cdd:TIGR02168  866 ELIEELESELEALLNERASLEEALALLrsELEELSEELRELEsKRSELRRELEELREKLAQLELRLEGLEVRIDNLQERL 945


                   ....*
gi 861483604  1325 EELGQ 1329
Cdd:TIGR02168  946 SEEYS 950
Smc COG1196
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ...
 471-1052 6.35e-23

Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 440809 [Multi-domain]  Cd Length: 983  Bit Score: 107.33  E-value: 6.35e-23
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 861483604  471 LQSSISNLSQAKEELEQAsQAQGAKLNAQVASLTAELTTLSATLQQQDQELAGLKQQAQKKQAQLAQSLQQQEQASQGLR 550
Cdd:COG1196   227 AELLLLKLRELEAELEEL-EAELEELEAELEELEAELAELEAELEELRLELEELELELEEAQAEEYELLAELARLEQDIA 305

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 861483604  551 HQVEQLSgSLKQKEKQLEEAARELDASRRDHAQQLATAAKAQEtslrERDAACQQLEALEKEKAAKLEILQQQLQAANEA 630
Cdd:COG1196   306 RLEERRR-ELEERLEELEEELAELEEELEELEEELEELEEELE----EAEEELEEAEAELAEAEEALLEAEAELAEAEEE 380

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 861483604  631 QDSAQNSVTQAQREKAELSQKVEELHALIEAAHQEQCEAQTQVAALEARLKAEQQKATEREKVAQEKAQLQEQlwslees 710
Cdd:COG1196   381 LEELAEELLEALRAAAELAAQLEELEEAEEALLERLERLEEELEELEEALAELEEEEEEEEEALEEAAEEEAE------- 453

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 861483604  711 lkitkgsLEEEKCRAAAALEEHQhhisemeaESRSLAEQHKQERKELEEEKAKRRGLGVQLQQLAETHQAETKALRQELA 790
Cdd:COG1196   454 -------LEEEEEALLELLAELL--------EEAALLEAALAELLEELAEAAARLLLLLEAEADYEGFLEGVKAALLLAG 518

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 861483604  791 KARtsnnmaereVELLVKEVKTWRKRYEDSQQGETQYGLQEQLTTLKE------EYEKSCQELRETKEKMAGIEAHSELQ 864
Cdd:COG1196   519 LRG---------LAGAVAVLIGVEAAYEAALEAALAAALQNIVVEDDEvaaaaiEYLKAAKAGRATFLPLDKIRARAALA 589

                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 861483604  865 IGQHQSELAQLHANLARALQQVQEKENRAQKLADDLSTLQEKMAATSKEVARLEALVRKAGEQQETASLELLKEPPKTRD 944
Cdd:COG1196   590 AALARGAIGAAVDLVASDLREADARYYVLGDTLLGRTLVAARLEAALRRAVTLAGRLREVTLEGEGGSAGGSLTGGSRRE 669

                         490       500       510       520       530       540       550       560
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 861483604  945 R-ESEWVEEQQGQQLCSTQAALRAMEREAEQMGTELEKLRAALMESQGQQQEERGQQEREVARLTQERGQAEADLALEKA 1023
Cdd:COG1196   670 LlAALLEAEAELEELAERLAEEELELEEALLAEEEEERELAEAEEERLEEELEEEALEEQLEAEREELLEELLEEEELLE 749

                         570       580
                  ....*....|....*....|....*....
gi 861483604 1024 AKAELEMRLQNALNEQQAEFANLQEALSR 1052
Cdd:COG1196   750 EEALEELPEPPDLEELERELERLEREIEA 778
PTZ00121 PTZ00121
MAEBL; Provisional
 1006-1724 2.26e-21

MAEBL; Provisional


Pssm-ID: 173412 [Multi-domain]  Cd Length: 2084  Bit Score: 102.53  E-value: 2.26e-21
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 861483604 1006 RLTQERGQAEADLALEKAAKAELEMRLQNALNEQQAEFANLQEALSRALSEKEGKDQELSKLCEQ----EAVQRME---- 1077
Cdd:PTZ00121 1110 KAEEARKAEEAKKKAEDARKAEEARKAEDARKAEEARKAEDAKRVEIARKAEDARKAEEARKAEDakkaEAARKAEevrk 1189

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 861483604 1078 LKELLQTVEQLKAQLAKKEKEQQ--QSARGASGENASGMGTQSEAVGKMEALRAKVSKLEQQCQQQQEEADSLARSLESE 1155
Cdd:PTZ00121 1190 AEELRKAEDARKAEAARKAEEERkaEEARKAEDAKKAEAVKKAEEAKKDAEEAKKAEEERNNEEIRKFEEARMAHFARRQ 1269

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 861483604 1156 RAFHVERDRALETLQGQLEEKARElgysQAASASAQRELATLRAKAQDHSKAEE-EWKAQVARGQQEAVRKGSLISSLEE 1234
Cdd:PTZ00121 1270 AAIKAEEARKADELKKAEEKKKAD----EAKKAEEKKKADEAKKKAEEAKKADEaKKKAEEAKKKADAAKKKAEEAKKAA 1345

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 861483604 1235 EVSILNRQVLEKEGESKELKrlviAESEKSQKLEERLRLLQMETASNSARAAERSSALREEVQSLREEVEKQRAASEnlr 1314
Cdd:PTZ00121 1346 EAAKAEAEAAADEAEAAEEK----AEAAEKKKEEAKKKADAAKKKAEEKKKADEAKKKAEEDKKKADELKKAAAAKK--- 1418

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 861483604 1315 qelasQAERAEELGQELKAWQEKFFQKEQALSALQLEHTSTQALVSELLP--AKHLCQQLQAEQVAAEKRHREELEQSKQ 1392
Cdd:PTZ00121 1419 -----KADEAKKKAEEKKKADEAKKKAEEAKKADEAKKKAEEAKKAEEAKkkAEEAKKADEAKKKAEEAKKADEAKKKAE 1493

                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 861483604 1393 AAGGLRTELMRAQRELGELVPLRQkvAEQERAAQQLR-AEKASYAEQLsmlKKAHGLLAEENRGLGERANLGRQFLEVEl 1471
Cdd:PTZ00121 1494 EAKKKADEAKKAAEAKKKADEAKK--AEEAKKADEAKkAEEAKKADEA---KKAEEKKKADELKKAEELKKAEEKKKAE- 1567

                         490       500       510       520       530       540       550       560
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 861483604 1472 dQAREKYIQELAAVRGDAETRLAEMR--QEVQSTTHELEVMTA----KYEGAKVKVlEERQRFQEERQKltaqVEQLEVF 1545
Cdd:PTZ00121 1568 -EAKKAEEDKNMALRKAEEAKKAEEAriEEVMKLYEEEKKMKAeeakKAEEAKIKA-EELKKAEEEKKK----VEQLKKK 1641

                         570       580       590       600       610       620       630       640
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 861483604 1546 QREQTKKVEELSKKladyDQASKVQQQKLKafqaqggesqQEAQRLQTQLNELQVQLSQKEQAAEHYKVQMEKAKTHYDA 1625
Cdd:PTZ00121 1642 EAEEKKKAEELKKA----EEENKIKAAEEA----------KKAEEDKKKAEEAKKAEEDEKKAAEALKKEAEEAKKAEEL 1707

                         650       660       670       680       690       700       710       720
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 861483604 1626 KKQQNQELQEQlqglEQLQKENKELRAEAERLGQELQQAGLKTKEA--EQTCRHLTAQVRSLEAQVAHADQQLRElgkfQ 1703
Cdd:PTZ00121 1708 KKKEAEEKKKA----EELKKAEEENKIKAEEAKKEAEEDKKKAEEAkkDEEEKKKIAHLKKEEEKKAEEIRKEKE----A 1779

                         730       740
                  ....*....|....*....|.
gi 861483604 1704 VASDALKSREPQAKPQLDLSI 1724
Cdd:PTZ00121 1780 VIEEELDEEDEKRRMEVDKKI 1800
PTZ00121 PTZ00121
MAEBL; Provisional
 572-1330 1.45e-20

MAEBL; Provisional


Pssm-ID: 173412 [Multi-domain]  Cd Length: 2084  Bit Score: 99.83  E-value: 1.45e-20
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 861483604  572 RELDASRRDHAQQLATAAKAQETSLRERDAACQQLEALEKEKAAKLEILQQQLQAANEAQDSAQNSVTQAQRE------- 644
Cdd:PTZ00121 1045 KDIIDEDIDGNHEGKAEAKAHVGQDEGLKPSYKDFDFDAKEDNRADEATEEAFGKAEEAKKTETGKAEEARKAeeakkka 1124

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 861483604  645 ----KAELSQKVEELHALIEAAHQEQCEAQTQVAALEARLKAEQQKATEREKVAQEKAQLQE-----QLWSLEESLKITK 715
Cdd:PTZ00121 1125 edarKAEEARKAEDARKAEEARKAEDAKRVEIARKAEDARKAEEARKAEDAKKAEAARKAEEvrkaeELRKAEDARKAEA 1204

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 861483604  716 GSLEEEKCRAaaalEEHQHHISEMEAESRSLAEQHK---QERKELEEEKAKRRGLGVQLQQLAE------THQAETKALR 786
Cdd:PTZ00121 1205 ARKAEEERKA----EEARKAEDAKKAEAVKKAEEAKkdaEEAKKAEEERNNEEIRKFEEARMAHfarrqaAIKAEEARKA 1280

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 861483604  787 QELAKARTSNNMAEREVELLVKEVKTWRKRYEDSQQGETQYGLQEQLTTLKEEYEKSCQELRETKE--KMAGIEAHSELQ 864
Cdd:PTZ00121 1281 DELKKAEEKKKADEAKKAEEKKKADEAKKKAEEAKKADEAKKKAEEAKKKADAAKKKAEEAKKAAEaaKAEAEAAADEAE 1360

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 861483604  865 IGQHQSELAQLHANLARALQQVQEKENRAQKLADDLSTLQEKMAATSKEVARLEALVRKAGEQQETASLELLKEPPKTRD 944
Cdd:PTZ00121 1361 AAEEKAEAAEKKKEEAKKKADAAKKKAEEKKKADEAKKKAEEDKKKADELKKAAAAKKKADEAKKKAEEKKKADEAKKKA 1440

                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 861483604  945 RESEWVEE--QQGQQLCSTQAALRAME--REAEQMGTELEKLRAAlmESQGQQQEERGQQEREVARLTQERGQAEADLAL 1020
Cdd:PTZ00121 1441 EEAKKADEakKKAEEAKKAEEAKKKAEeaKKADEAKKKAEEAKKA--DEAKKKAEEAKKKADEAKKAAEAKKKADEAKKA 1518

                         490       500       510       520       530       540       550       560
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 861483604 1021 EKAAKAElemRLQNALNEQQAEFANLQEALSRAlsEKEGKDQELSKLCEQEAVQRMELKELLQTVEQLKAQLAKKEKEQQ 1100
Cdd:PTZ00121 1519 EEAKKAD---EAKKAEEAKKADEAKKAEEKKKA--DELKKAEELKKAEEKKKAEEAKKAEEDKNMALRKAEEAKKAEEAR 1593

                         570       580       590       600       610       620       630       640
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 861483604 1101 QSARGASGENASGMgtQSEAVGKMEALRAKVSKLeQQCQQQQEEADSLARSLESERAFHVERDRALETLQGQLEEKAREL 1180
Cdd:PTZ00121 1594 IEEVMKLYEEEKKM--KAEEAKKAEEAKIKAEEL-KKAEEEKKKVEQLKKKEAEEKKKAEELKKAEEENKIKAAEEAKKA 1670

                         650       660       670       680       690       700       710       720
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 861483604 1181 GYSQAASASAQRELATLRAKAQDHSKAEEEWKA--QVARGQQEAVRKGSLISSLEEEVSILNRQVLEKEGESKELKRLVI 1258
Cdd:PTZ00121 1671 EEDKKKAEEAKKAEEDEKKAAEALKKEAEEAKKaeELKKKEAEEKKKAEELKKAEEENKIKAEEAKKEAEEDKKKAEEAK 1750

                         730       740       750       760       770       780       790
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 861483604 1259 AESEKSQKLEErlrLLQMETASNSARAAERSSALREEVqslREEVEKQRAASENLRQELASQAERAEELGQE 1330
Cdd:PTZ00121 1751 KDEEEKKKIAH---LKKEEEKKAEEIRKEKEAVIEEEL---DEEDEKRRMEVDKKIKDIFDNFANIIEGGKE 1816
Smc COG1196
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ...
 1123-1658 5.42e-20

Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 440809 [Multi-domain]  Cd Length: 983  Bit Score: 97.70  E-value: 5.42e-20
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 861483604 1123 KMEALRAKVSKLEQQCQQQQEEADSLARSLESERAFHVERDRALETLQGQLEEKARELG--------------YSQAASA 1188
Cdd:COG1196   240 ELEELEAELEELEAELEELEAELAELEAELEELRLELEELELELEEAQAEEYELLAELArleqdiarleerrrELEERLE 319

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 861483604 1189 SAQRELATLRAKAQDHSKAEEEWKAQVARGQQEAVRKGSLISSLEEEVSILNRQVLEKEGESKELKRLVIAESEKSQKLE 1268
Cdd:COG1196   320 ELEEELAELEEELEELEEELEELEEELEEAEEELEEAEAELAEAEEALLEAEAELAEAEEELEELAEELLEALRAAAELA 399

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 861483604 1269 ERLRLLQMETASNSARAAERSSALREEVQSLREEVEKQRAASENLRQELASQAERAEELGQELKAWQEKFFQKEQALSAL 1348
Cdd:COG1196   400 AQLEELEEAEEALLERLERLEEELEELEEALAELEEEEEEEEEALEEAAEEEAELEEEEEALLELLAELLEEAALLEAAL 479

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 861483604 1349 QLEHTSTQALVSELLPAKHLCQQLQAEQVAAEKRHREELEQSKQAAGGLR---TELMRAQRELGELVPLRQKVAEQERAA 1425
Cdd:COG1196   480 AELLEELAEAAARLLLLLEAEADYEGFLEGVKAALLLAGLRGLAGAVAVLigvEAAYEAALEAALAAALQNIVVEDDEVA 559

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 861483604 1426 QQ----LRAEKASYAEQLSMLKKAHGLLAEENRGLGERAnLGRQFLEVELDQAREKYIQELAAVRGDAETRLAEMRQEVQ 1501
Cdd:COG1196   560 AAaieyLKAAKAGRATFLPLDKIRARAALAAALARGAIG-AAVDLVASDLREADARYYVLGDTLLGRTLVAARLEAALRR 638

                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 861483604 1502 STTHELEVMTAKYEGAKVKVLEERQRFQEERQKLTAQVEQLEvfQREQTKKVEELSKKLADYDQASKVQQQKLKAFQAQG 1581
Cdd:COG1196   639 AVTLAGRLREVTLEGEGGSAGGSLTGGSRRELLAALLEAEAE--LEELAERLAEEELELEEALLAEEEEERELAEAEEER 716

                         490       500       510       520       530       540       550
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 861483604 1582 GESQQEAQRLQTQLNELQVQLSQKEQAAEHYKVQMEKAKTHYDAKkqqnqelqeqlqgLEQLQKENKELRAEAERLG 1658
Cdd:COG1196   717 LEEELEEEALEEQLEAEREELLEELLEEEELLEEEALEELPEPPD-------------LEELERELERLEREIEALG 780
Smc COG1196
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ...
 215-811 1.73e-19

Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 440809 [Multi-domain]  Cd Length: 983  Bit Score: 96.16  E-value: 1.73e-19
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 861483604  215 QMRRLKKQ---------LADERNNRDeLELELAEHRKLLTEKDAQISMMQQRIDRLALLNEKQAAspLEpRELEELRGKN 285
Cdd:COG1196   201 QLEPLERQaekaeryreLKEELKELE-AELLLLKLRELEAELEELEAELEELEAELEELEAELAE--LE-AELEELRLEL 276

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 861483604  286 ESLTFRLHETLKQCQDLKTEKGQMDRKINQLSEEngdlsfklrefasnLQQLQGALNELTEEHskatQQWVEKQAHLEKE 365
Cdd:COG1196   277 EELELELEEAQAEEYELLAELARLEQDIARLEER--------------RRELEERLEELEEEL----AELEEELEELEEE 338

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 861483604  366 LSTALQDKKCLEEKNEILQGKLSQLEERLAQLPESPRQEKGEVLGDVLQLESLKQEAATLATNNTQLQARVEMLENEQGQ 445
Cdd:COG1196   339 LEELEEELEEAEEELEEAEAELAEAEEALLEAEAELAEAEEELEELAEELLEALRAAAELAAQLEELEEAEEALLERLER 418

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 861483604  446 KEAQLLGERSHFEEEKQQLASLITNLQSSISNLSQAKEELEQASQAQGAKLNAQVASLTAELTTLSATLQQQDQELAGLK 525
Cdd:COG1196   419 LEEELEELEEALAELEEEEEEEEEALEEAAEEEAELEEEEEALLELLAELLEEAALLEAALAELLEELAEAAARLLLLLE 498

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 861483604  526 QQAQKKQAQLAQSLQQQEQASQGLRHQVEQLSGSLKQKEKQLEEAareLDASRRDHAQQLATAAKAQETSLRERDAACQQ 605
Cdd:COG1196   499 AEADYEGFLEGVKAALLLAGLRGLAGAVAVLIGVEAAYEAALEAA---LAAALQNIVVEDDEVAAAAIEYLKAAKAGRAT 575

                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 861483604  606 LEALEKEKAAKLEILQQQLQAANEAQDSAqnsvtQAQREKAELSQKVEELHALIEAAHQEQCEAQTQVAALEARLKAEQQ 685
Cdd:COG1196   576 FLPLDKIRARAALAAALARGAIGAAVDLV-----ASDLREADARYYVLGDTLLGRTLVAARLEAALRRAVTLAGRLREVT 650

                         490       500       510       520       530       540       550       560
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 861483604  686 KATEREKVAQEKAQLQEQlwSLEESLKITKGSLEEEKCRAAAALEEHQHHISEMEAESRSLAEQHKQERKELEEEKAKRR 765
Cdd:COG1196   651 LEGEGGSAGGSLTGGSRR--ELLAALLEAEAELEELAERLAEEELELEEALLAEEEEERELAEAEEERLEEELEEEALEE 728

                         570       580       590       600
                  ....*....|....*....|....*....|....*....|....*....
gi 861483604  766 GLGVQLQQLAETHQAETKALRQELAKARTSN---NMAEREVELLVKEVK 811
Cdd:COG1196   729 QLEAEREELLEELLEEEELLEEEALEELPEPpdlEELERELERLEREIE 777
SMC_prok_B TIGR02168
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...
 1006-1701 2.17e-15

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274008 [Multi-domain]  Cd Length: 1179  Bit Score: 82.80  E-value: 2.17e-15
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 861483604  1006 RLTQERGQAEADLALE--KAAKAELEmRLQNALNEQQAEFANLQEALSRALSEKEGKDQELSKLCEQEAVQRMELKELLQ 1083
Cdd:TIGR02168  217 ELKAELRELELALLVLrlEELREELE-ELQEELKEAEEELEELTAELQELEEKLEELRLEVSELEEEIEELQKELYALAN 295

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 861483604  1084 TVEQLKAQLakkeKEQQQSARGASGENASGMGTQSEAVGKMEALRAKVSKLEQQCQQQQEEADSLARSLESERAFHVERD 1163
Cdd:TIGR02168  296 EISRLEQQK----QILRERLANLERQLEELEAQLEELESKLDELAEELAELEEKLEELKEELESLEAELEELEAELEELE 371

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 861483604  1164 RALETLQGQLEEKARELGYSQAASASAQRELATLRAKAQDHSKAEEEWKAQVARGQQEAVRKGslISSLEEEVSILNRQV 1243
Cdd:TIGR02168  372 SRLEELEEQLETLRSKVAQLELQIASLNNEIERLEARLERLEDRRERLQQEIEELLKKLEEAE--LKELQAELEELEEEL 449

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 861483604  1244 LEKEGESKELKRLVIAESEKSQKLEERLRLLQMETASNSARAAerssalreevqSLREEVEKQRAASENLRQELASQAER 1323
Cdd:TIGR02168  450 EELQEELERLEEALEELREELEEAEQALDAAERELAQLQARLD-----------SLERLQENLEGFSEGVKALLKNQSGL 518

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 861483604  1324 AEELGQ--ELKAWQEKFfqkEQALSALQLEHTstQALVSELLPAKHLCQQLQAeQVAAEKRHREELEQSK--QAAGGLRT 1399
Cdd:TIGR02168  519 SGILGVlsELISVDEGY---EAAIEAALGGRL--QAVVVENLNAAKKAIAFLK-QNELGRVTFLPLDSIKgtEIQGNDRE 592

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 861483604  1400 ELMRAQRELGELVPLRQKVAEQERAAQQLRAEKA---SYAEQLSMLKK----------------AHGLLAeenrGLGERA 1460
Cdd:TIGR02168  593 ILKNIEGFLGVAKDLVKFDPKLRKALSYLLGGVLvvdDLDNALELAKKlrpgyrivtldgdlvrPGGVIT----GGSAKT 668

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 861483604  1461 NLGRQFLEVELDQAREKyIQELAAVRGDAETRLAEMRQEVQSTTHELEVMTAKYEGAKVKVLEER---QRFQEERQKLTA 1537
Cdd:TIGR02168  669 NSSILERRREIEELEEK-IEELEEKIAELEKALAELRKELEELEEELEQLRKELEELSRQISALRkdlARLEAEVEQLEE 747

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 861483604  1538 QVEQLEVFQREQTKKVEELSKKLADYDQASKVQQQKLKAFQAQGGESQQEAQRLQTQLNELQVQLSQKEQAAEHYKVQME 1617
Cdd:TIGR02168  748 RIAQLSKELTELEAEIEELEERLEEAEEELAEAEAEIEELEAQIEQLKEELKALREALDELRAELTLLNEEAANLRERLE 827

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 861483604  1618 KAKTHYDAKKQQNQELQEQLQG-----------LEQLQKENKELRAEAERLGQELQQAGLKTKEAEQTCRHLTAQVRSLE 1686
Cdd:TIGR02168  828 SLERRIAATERRLEDLEEQIEElsedieslaaeIEELEELIEELESELEALLNERASLEEALALLRSELEELSEELRELE 907

                          730
                   ....*....|....*
gi 861483604  1687 AQVAHADQQLRELGK 1701
Cdd:TIGR02168  908 SKRSELRRELEELRE 922
SMC_N pfam02463
RecF/RecN/SMC N terminal domain; This domain is found at the N terminus of SMC proteins. The ...
 350-1101 1.66e-11

RecF/RecN/SMC N terminal domain; This domain is found at the N terminus of SMC proteins. The SMC (structural maintenance of chromosomes) superfamily proteins have ATP-binding domains at the N- and C-termini, and two extended coiled-coil domains separated by a hinge in the middle. The eukaryotic SMC proteins form two kind of heterodimers: the SMC1/SMC3 and the SMC2/SMC4 types. These heterodimers constitute an essential part of higher order complexes, which are involved in chromatin and DNA dynamics. This family also includes the RecF and RecN proteins that are involved in DNA metabolism and recombination.


Pssm-ID: 426784 [Multi-domain]  Cd Length: 1161  Bit Score: 70.00  E-value: 1.66e-11
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 861483604   350 KATQQWVEKQAHLEKELSTALQDKKcLEEKNEilqgKLSQLEERLAQLPESPRQEKgevlgdvLQLESLKQEAATLATNN 429
Cdd:pfam02463  146 IIAMMKPERRLEIEEEAAGSRLKRK-KKEALK----KLIEETENLAELIIDLEELK-------LQELKLKEQAKKALEYY 213

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 861483604   430 TQLQARVEMLENEQGQKEAQLLGERSHFEEEKQQLASLITNLQSSISNLSQAKEELEQASQAQGAKLNAQVASLTAELTT 509
Cdd:pfam02463  214 QLKEKLELEEEYLLYLDYLKLNEERIDLLQELLRDEQEEIESSKQEIEKEEEKLAQVLKENKEEEKEKKLQEEELKLLAK 293

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 861483604   510 LSATLQQQDQELAGLKQQAQKKQAQLAQSLQQQEQASQGLRHQVEQLSGSLKQKEKQLEEAARELDASRrdhaQQLATAA 589
Cdd:pfam02463  294 EEEELKSELLKLERRKVDDEEKLKESEKEKKKAEKELKKEKEEIEELEKELKELEIKREAEEEEEEELE----KLQEKLE 369

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 861483604   590 KAQETSLRERDAACQQLEALEKEKAAKLEILQQQLQAANEAQDSAQNSVTQAQREKAELSQKVEELHALIEAAHQEQCEA 669
Cdd:pfam02463  370 QLEEELLAKKKLESERLSSAAKLKEEELELKSEEEKEAQLLLELARQLEDLLKEEKKEELEILEEEEESIELKQGKLTEE 449

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 861483604   670 QTQVAALEARLKAEQQKAtEREKVAQEKAQLQEQLWSLEESLKITKGSLEEEKCRAAAALEEHQHHISEMEAESRSLAEQ 749
Cdd:pfam02463  450 KEELEKQELKLLKDELEL-KKSEDLLKETQLVKLQEQLELLLSRQKLEERSQKESKARSGLKVLLALIKDGVGGRIISAH 528

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 861483604   750 HKQERKELEEEKAKRRGLGVQLQQLAETHQAETKA--LRQELAKARTSNNMAEREVELLVKEVKTWRKRYEDSQQGETQY 827
Cdd:pfam02463  529 GRLGDLGVAVENYKVAISTAVIVEVSATADEVEERqkLVRALTELPLGARKLRLLIPKLKLPLKSIAVLEIDPILNLAQL 608

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 861483604   828 GLQEQLTTLKEEYEKSCQELRETKEKMAGIEAHSELQIG-QHQSELAQLHANLARALQQVQEKEnRAQKLADDLSTLQEK 906
Cdd:pfam02463  609 DKATLEADEDDKRAKVVEGILKDTELTKLKESAKAKESGlRKGVSLEEGLAEKSEVKASLSELT-KELLEIQELQEKAES 687

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 861483604   907 MAATSKEVARLEALVRKAGEQQETASLELLKEPPKTRDRESEWVEEQQGQQLCSTQAALRAMEREAEQMGTELEKLRAAL 986
Cdd:pfam02463  688 ELAKEEILRRQLEIKKKEQREKEELKKLKLEAEELLADRVQEAQDKINEELKLLKQKIDEEEEEEEKSRLKKEEKEEEKS 767

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 861483604   987 MESQGQQQEERGQQEREVARLTQERGQAEADLALEKAAKAElEMRLQNALNEQQAEFANLQEALSRALSEKEGKDQELSK 1066
Cdd:pfam02463  768 ELSLKEKELAEEREKTEKLKVEEEKEEKLKAQEEELRALEE-ELKEEAELLEEEQLLIEQEEKIKEEELEELALELKEEQ 846

                          730       740       750
                   ....*....|....*....|....*....|....*
gi 861483604  1067 LCEQEAVQRMELKELLQTVEQLKAQLAKKEKEQQQ 1101
Cdd:pfam02463  847 KLEKLAEEELERLEEEITKEELLQELLLKEEELEE 881
Mplasa_alph_rch TIGR04523
helix-rich Mycoplasma protein; Members of this family occur strictly within a subset of ...
 217-715 1.34e-09

helix-rich Mycoplasma protein; Members of this family occur strictly within a subset of Mycoplasma species. Members average 750 amino acids in length, including signal peptide. Sequences are predicted (Jpred 3) to be almost entirely alpha-helical. These sequences show strong periodicity (consistent with long alpha helical structures) and low complexity rich in D,E,N,Q, and K. Genes encoding these proteins are often found in tandem. The function is unknown.


Pssm-ID: 275316 [Multi-domain]  Cd Length: 745  Bit Score: 63.50  E-value: 1.34e-09
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 861483604   217 RRLKKQLADERNNRDELELELAEHRKLLTEKDAQISMMQQRIDRLALLNEKQAaspLEPRELEELRGKNESLTFRLHETL 296
Cdd:TIGR04523  162 NDLKKQKEELENELNLLEKEKLNIQKNIDKIKNKLLKLELLLSNLKKKIQKNK---SLESQISELKKQNNQLKDNIEKKQ 238

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 861483604   297 KQCQDLKTEKGQMDRKINQLSEENGDLSFKLREFASNLQQLQGALNELTEEHSKATQQWV----EKQAHLEKELSTALQD 372
Cdd:TIGR04523  239 QEINEKTTEISNTQTQLNQLKDEQNKIKKQLSEKQKELEQNNKKIKELEKQLNQLKSEISdlnnQKEQDWNKELKSELKN 318

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 861483604   373 KkclEEKNEILQGKLSQLEERLAQLPEsprqekgevlgdvlQLESLKQEAATLATNNTQLQARVEmlenEQGQKEAQLLG 452
Cdd:TIGR04523  319 Q---EKKLEEIQNQISQNNKIISQLNE--------------QISQLKKELTNSESENSEKQRELE----EKQNEIEKLKK 377

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 861483604   453 ERSHFEEEKQQLASLITNLQSSISNLSQAKEELEQ---ASQAQGAKLNAQVASLTAELTTLSAT---LQQQDQELAGLKQ 526
Cdd:TIGR04523  378 ENQSYKQEIKNLESQINDLESKIQNQEKLNQQKDEqikKLQQEKELLEKEIERLKETIIKNNSEikdLTNQDSVKELIIK 457

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 861483604   527 QAQKKQAQLAQSLQQQEQASQGLRHQVEQLSGSLKQKEKQLEeaarELDASRRDHAQQLATAAKAQETSLRERdaacQQL 606
Cdd:TIGR04523  458 NLDNTRESLETQLKVLSRSINKIKQNLEQKQKELKSKEKELK----KLNEEKKELEEKVKDLTKKISSLKEKI----EKL 529

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 861483604   607 EALEKEKAAKLEILQQQLQAANEAQDSaqnsvTQAQREKAELSQKVEELHALIEAAHQEQCEAQTQVaalearlkaeQQK 686
Cdd:TIGR04523  530 ESEKKEKESKISDLEDELNKDDFELKK-----ENLEKEIDEKNKEIEELKQTQKSLKKKQEEKQELI----------DQK 594

                          490       500
                   ....*....|....*....|....*....
gi 861483604   687 ATEREKVAQEKAQLQEQLWSLEESLKITK 715
Cdd:TIGR04523  595 EKEKKDLIKEIEEKEKKISSLEKELEKAK 623
MARTX_Nterm NF012221
MARTX multifunctional-autoprocessing repeats-in-toxin holotoxin N-terminal region; This model ...
 406-651 2.34e-09

MARTX multifunctional-autoprocessing repeats-in-toxin holotoxin N-terminal region; This model describes the N-terminal 1900 amino acids of MARTX family multifunctional-autoprocessing repeats-in-toxin holotoxins, which contain both repeat regions that facilitate their entry into eukaryotic target cells, and multiple effector domains.


Pssm-ID: 467957 [Multi-domain]  Cd Length: 1848  Bit Score: 62.93  E-value: 2.34e-09
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 861483604  406 GEVLGDVLQLESLKQEAATLATNNTQLQARVEMLeNEQGQKEAqllgERSHFEEEKQQLASLITNLQSSISNLSQAKeeL 485
Cdd:NF012221 1528 GYILDNVVATSESSQQADAVSKHAKQDDAAQNAL-ADKERAEA----DRQRLEQEKQQQLAAISGSQSQLESTDQNA--L 1600

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 861483604  486 EQASQAQGAKLNAQVASLTAELTTLSATL-----QQQDQELAGLKQQAQKKQAQLAQSLQQQEQASQGLRHQVEQLSGSL 560
Cdd:NF012221 1601 ETNGQAQRDAILEESRAVTKELTTLAQGLdaldsQATYAGESGDQWRNPFAGGLLDRVQEQLDDAKKISGKQLADAKQRH 1680

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 861483604  561 KQKEKQLEEAARELDA--SRRDHAQQLATAAKAQ---ETSLRERDAACQQLEALEKEKAAKLEILQQQlQAANEAQDSAQ 635
Cdd:NF012221 1681 VDNQQKVKDAVAKSEAgvAQGEQNQANAEQDIDDakaDAEKRKDDALAKQNEAQQAESDANAAANDAQ-SRGEQDASAAE 1759

                         250
                  ....*....|....*.
gi 861483604  636 NSVTQAQREKAELSQK 651
Cdd:NF012221 1760 NKANQAQADAKGAKQD 1775
PRK03918 PRK03918
DNA double-strand break repair ATPase Rad50;
205-831 3.52e-08

DNA double-strand break repair ATPase Rad50;


Pssm-ID: 235175 [Multi-domain]  Cd Length: 880  Bit Score: 58.92  E-value: 3.52e-08
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 861483604  205 MGDILQTPQFQMRRLKKQLADERNNRDELElelaEHRKLLTEKDAQISMMQQRIDRLAllnEKQAASPLEPRELEELRGK 284
Cdd:PRK03918  167 LGEVIKEIKRRIERLEKFIKRTENIEELIK----EKEKELEEVLREINEISSELPELR---EELEKLEKEVKELEELKEE 239

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 861483604  285 NESLTFRLHETLKQCQDLKTEKGQMDRKINQLSEENGDLSFKLREfasnLQQLQGaLNELTEEHSKATQQWVEKQAHLEK 364
Cdd:PRK03918  240 IEELEKELESLEGSKRKLEEKIRELEERIEELKKEIEELEEKVKE----LKELKE-KAEEYIKLSEFYEEYLDELREIEK 314

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 861483604  365 ELSTALQDKKCLEEKNEILQGKLSQLEErLAQLPESPRQEKGEVLGDVLQLESLKQeaatLATNNTQLQARVEMLENEQG 444
Cdd:PRK03918  315 RLSRLEEEINGIEERIKELEEKEERLEE-LKKKLKELEKRLEELEERHELYEEAKA----KKEELERLKKRLTGLTPEKL 389

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 861483604  445 QKEAQLLGER-SHFEEEKQQLASLITNLQSSISNLSQAKEELEQASQ---AQGAKLNAQ-----VASLTAELTTLSATLQ 515
Cdd:PRK03918  390 EKELEELEKAkEEIEEEISKITARIGELKKEIKELKKAIEELKKAKGkcpVCGRELTEEhrkelLEEYTAELKRIEKELK 469

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 861483604  516 QQDQELaglkqqaqkkqaqlaqslqqqeqasqglrhqvEQLSGSLKQKEKQLEEaARELDASRRDHAQQLATAAKAQETS 595
Cdd:PRK03918  470 EIEEKE--------------------------------RKLRKELRELEKVLKK-ESELIKLKELAEQLKELEEKLKKYN 516

                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 861483604  596 LRERDAACQQLEALeKEKAAKLEILQQQLQAANEAQDSAQNSVTQAQREKAELSQKVEELHALIEAAHQEQCEaqtQVAA 675
Cdd:PRK03918  517 LEELEKKAEEYEKL-KEKLIKLKGEIKSLKKELEKLEELKKKLAELEKKLDELEEELAELLKELEELGFESVE---ELEE 592

                         490       500       510       520       530       540       550       560
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 861483604  676 LEARLKAEQQKATEREKVAQEKAQLQEQLWSLEESLKITKGSLEEEKcraaAALEEHQHHISEMeaESRSLAEQHKQERK 755
Cdd:PRK03918  593 RLKELEPFYNEYLELKDAEKELEREEKELKKLEEELDKAFEELAETE----KRLEELRKELEEL--EKKYSEEEYEELRE 666

                         570       580       590       600       610       620       630
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 861483604  756 ELEEEKAKRRGLGVQLQQLaETHQAETKALRQELAKARTSNNMAEREVELLVK---EVKTWRKRYEDSQQGETQYGLQE 831
Cdd:PRK03918  667 EYLELSRELAGLRAELEEL-EKRREEIKKTLEKLKEELEEREKAKKELEKLEKaleRVEELREKVKKYKALLKERALSK 744
DUF3584 pfam12128
Protein of unknown function (DUF3584); This protein is found in bacteria and eukaryotes. ...
 1161-1720 1.30e-07

Protein of unknown function (DUF3584); This protein is found in bacteria and eukaryotes. Proteins in this family are typically between 943 to 1234 amino acids in length. This family contains a P-loop motif suggesting it is a nucleotide binding protein. It may be involved in replication.


Pssm-ID: 432349 [Multi-domain]  Cd Length: 1191  Bit Score: 57.16  E-value: 1.30e-07
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 861483604  1161 ERDRALETLQGQLEEKARELGYSQAASASAQRELATLRA-KAQDHSKAEEEWKAQVARGQQEAVRKGSLISSLEEEVSIL 1239
Cdd:pfam12128  248 QEFNTLESAELRLSHLHFGYKSDETLIASRQEERQETSAeLNQLLRTLDDQWKEKRDELNGELSAADAAVAKDRSELEAL 327

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 861483604  1240 NRQVLEKEGESKE-----LKRLVIAESEKSQkLEERLRLL----QMETASNSARAAERSSALREEVQSL-------REEV 1303
Cdd:pfam12128  328 EDQHGAFLDADIEtaaadQEQLPSWQSELEN-LEERLKALtgkhQDVTAKYNRRRSKIKEQNNRDIAGIkdklakiREAR 406

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 861483604  1304 EKQRAASENLRQELASQAEraEELGQELKAWQEKFFQKEQALSALQLEHTSTQALVSELLpakhlcqQLQAEQVAAEkRH 1383
Cdd:pfam12128  407 DRQLAVAEDDLQALESELR--EQLEAGKLEFNEEEYRLKSRLGELKLRLNQATATPELLL-------QLENFDERIE-RA 476

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 861483604  1384 REELEQSkqaagglRTELMRAQRELGELVPLRQKVAEQ----ERAAQQLRAEKASYAEQLSmlKKAHGLLA--------- 1450
Cdd:pfam12128  477 REEQEAA-------NAEVERLQSELRQARKRRDQASEAlrqaSRRLEERQSALDELELQLF--PQAGTLLHflrkeapdw 547

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 861483604  1451 EENRG-LGERANLGRQFLEVELDQAREKYIQELAAVRGDAEtrlaemRQEVQSTTHELEVMTAKYEGAKVKVLEERQRFQ 1529
Cdd:pfam12128  548 EQSIGkVISPELLHRTDLDPEVWDGSVGGELNLYGVKLDLK------RIDVPEWAASEEELRERLDKAEEALQSAREKQA 621

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 861483604  1530 EERQKLTAQVEQLEVFQREQTKKVEELSKKLADYDQASKVQQQ-KLKAFQAQGGESQQEAQRLQTQLNELQVQLSQKEQA 1608
Cdd:pfam12128  622 AAEEQLVQANGELEKASREETFARTALKNARLDLRRLFDEKQSeKDKKNKALAERKDSANERLNSLEAQLKQLDKKHQAW 701

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 861483604  1609 AEHYKVQMEKAKTHYDAKKQQNQELQEQLQGL--EQLQKENKELRAEAERLGQELQQAGLKTKEAEQTCRHLTAQVRSLE 1686
Cdd:pfam12128  702 LEEQKEQKREARTEKQAYWQVVEGALDAQLALlkAAIAARRSGAKAELKALETWYKRDLASLGVDPDVIAKLKREIRTLE 781

                          570       580       590
                   ....*....|....*....|....*....|....
gi 861483604  1687 AQVAHADQQLRELGKFQvasDALKSREPQAKPQL 1720
Cdd:pfam12128  782 RKIERIAVRRQEVLRYF---DWYQETWLQRRPRL 812
CCDC158 pfam15921
Coiled-coil domain-containing protein 158; CCDC158 is a family of proteins found in eukaryotes. ...
 242-858 1.56e-07

Coiled-coil domain-containing protein 158; CCDC158 is a family of proteins found in eukaryotes. The function is not known.


Pssm-ID: 464943 [Multi-domain]  Cd Length: 1112  Bit Score: 57.05  E-value: 1.56e-07
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 861483604   242 KLLTEKDAQISMMQQRIdrlallnekqaaSPLEPrELEELRGKNESltfRLHETLKQCQDlktekgQMDRKINQLSEENG 321
Cdd:pfam15921  224 KILRELDTEISYLKGRI------------FPVED-QLEALKSESQN---KIELLLQQHQD------RIEQLISEHEVEIT 281

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 861483604   322 DLSFKLREFASNLQQLQGALNELTEEHSKATQQWVEKQAHLEkelSTALQDKKCLEEKNEILQGKLSQLEERLAQLPESP 401
Cdd:pfam15921  282 GLTEKASSARSQANSIQSQLEIIQEQARNQNSMYMRQLSDLE---STVSQLRSELREAKRMYEDKIEELEKQLVLANSEL 358

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 861483604   402 RQEKGEvlgdvlqLESLKQEAATLATNNTQLQARVEMLENEQGQKEAQ-----------------LLGERSHFEEEKQQL 464
Cdd:pfam15921  359 TEARTE-------RDQFSQESGNLDDQLQKLLADLHKREKELSLEKEQnkrlwdrdtgnsitidhLRRELDDRNMEVQRL 431

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 861483604   465 ASLITNLQSSisnlSQAKEELEQASQAQGAKLNAQVASLTAELTTLSATLQQQDQELAGLKQQAQKKQAQlaqslqqqeq 544
Cdd:pfam15921  432 EALLKAMKSE----CQGQMERQMAAIQGKNESLEKVSSLTAQLESTKEMLRKVVEELTAKKMTLESSERT---------- 497

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 861483604   545 asqglrhqVEQLSGSLKQKEKQLEEAARELDA--SRRDHAQQLATAAKAQETSLRERDAACQQLEALEKEKAAKLEILQQ 622
Cdd:pfam15921  498 --------VSDLTASLQEKERAIEATNAEITKlrSRVDLKLQELQHLKNEGDHLRNVQTECEALKLQMAEKDKVIEILRQ 569

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 861483604   623 QLQAANEAQDSAQNSVTQAQREKAELSQKV-------EELHALIEAAHQEQCEAQTQVAALE-----------ARLKAEQ 684
Cdd:pfam15921  570 QIENMTQLVGQHGRTAGAMQVEKAQLEKEIndrrlelQEFKILKDKKDAKIRELEARVSDLElekvklvnagsERLRAVK 649

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 861483604   685 QKATEREKVAQEKAQLQEQLWSLEESLKITKGSLEEEKcraaaaleehqhhiSEMEAESRSLAEQHKQERKELEEEKAKR 764
Cdd:pfam15921  650 DIKQERDQLLNEVKTSRNELNSLSEDYEVLKRNFRNKS--------------EEMETTTNKLKMQLKSAQSELEQTRNTL 715

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 861483604   765 RGLgvqlqQLAETHQAETK-ALRQELAKARTSNNMAEREVELLVKEVKTWRKryEDSQQGETQYGLQEQLTTLKEEYEKS 843
Cdd:pfam15921  716 KSM-----EGSDGHAMKVAmGMQKQITAKRGQIDALQSKIQFLEEAMTNANK--EKHFLKEEKNKLSQELSTVATEKNKM 788

                          650       660
                   ....*....|....*....|..
gi 861483604   844 CQEL-------RETKEKMAGIE 858
Cdd:pfam15921  789 AGELevlrsqeRRLKEKVANME 810
PHA03307 PHA03307
transcriptional regulator ICP4; Provisional
 1748-2003 2.23e-04

transcriptional regulator ICP4; Provisional


Pssm-ID: 223039 [Multi-domain]  Cd Length: 1352  Bit Score: 46.70  E-value: 2.23e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 861483604 1748 PDGTSVPGEPASPISQRlPPKVESLESLYFTPIPARGPA--PLESSLDSLGEPFLDSGRKTRSA-------------RRR 1812
Cdd:PHA03307  192 EPPPSTPPAAASPRPPR-RSSPISASASSPAPAPGRSAAddAGASSSDSSSSESSGCGWGPENEcplprpapitlptRIW 270

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 861483604 1813 TTQIINITMTKKLDVEEPDSANSSfYSTRSAPASQAGLRATSSTQSLARLGSPDDGNSAllslpgyrpTTRSSTRRSQAG 1892
Cdd:PHA03307  271 EASGWNGPSSRPGPASSSSSPRER-SPSPSPSSPGSGPAPSSPRASSSSSSSRESSSSS---------TSSSSESSRGAA 340

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 861483604 1893 VSSGAPPGRNsfymGTCQDEPeqldDWNRIAELQQRnrvCPPHLKTCYPLESRPSlglatitdeemktgdpqETLRRASM 1972
Cdd:PHA03307  341 VSPGPSPSRS----PSPSRPP----PPADPSSPRKR---PRPSRAPSSPAASAGR-----------------PTRRRARA 392

                         250       260       270
                  ....*....|....*....|....*....|....
gi 861483604 1973 Q---PGQIAEGAGITTRQQRKRVSSETHQGPGTP 2003
Cdd:PHA03307  393 AvagRARRRDATGRFPAGRPRPSPLDAGAASGAF 426
MARTX_Nterm NF012221
MARTX multifunctional-autoprocessing repeats-in-toxin holotoxin N-terminal region; This model ...
 1370-1723 2.02e-03

MARTX multifunctional-autoprocessing repeats-in-toxin holotoxin N-terminal region; This model describes the N-terminal 1900 amino acids of MARTX family multifunctional-autoprocessing repeats-in-toxin holotoxins, which contain both repeat regions that facilitate their entry into eukaryotic target cells, and multiple effector domains.


Pssm-ID: 467957 [Multi-domain]  Cd Length: 1848  Bit Score: 43.67  E-value: 2.02e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 861483604 1370 QQLQAEQVAAEKRHREELEQSKQAAG-GLRTELMRAQRELGELVPLRQKVAEQERAAQQLRAEKASYAEQLSMLKKahgl 1448
Cdd:NF012221 1501 QQKTLKLTAKAGSNRLEFKGTGHNDGlGYILDNVVATSESSQQADAVSKHAKQDDAAQNALADKERAEADRQRLEQ---- 1576

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 861483604 1449 laEENRGLGERAnlGRQF-LEVELDQAREKYIQ-ELAAVRGDAEtrlaEMRQEVQSTTHELEVMTAKYEGAKVKVLEERQ 1526
Cdd:NF012221 1577 --EKQQQLAAIS--GSQSqLESTDQNALETNGQaQRDAILEESR----AVTKELTTLAQGLDALDSQATYAGESGDQWRN 1648

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 861483604 1527 RFQEeRQKLTAQvEQLEVFQREQTKKVEELSKKLADYDQASKVQQQKLKAFQAQGGESQQEAQrLQTQLNELQVQLSQKE 1606
Cdd:NF012221 1649 PFAG-GLLDRVQ-EQLDDAKKISGKQLADAKQRHVDNQQKVKDAVAKSEAGVAQGEQNQANAE-QDIDDAKADAEKRKDD 1725

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 861483604 1607 QAAEHYKVQMEKAKTHYDAKKQQNQELQeqlqglEQLQKENKELRAEAErlgqelqQAGLKTKEAEQTCRH------LTA 1680
Cdd:NF012221 1726 ALAKQNEAQQAESDANAAANDAQSRGEQ------DASAAENKANQAQAD-------AKGAKQDESDKPNRQgaagsgLSG 1792

                         330       340       350       360
                  ....*....|....*....|....*....|....*....|...
gi 861483604 1681 QVRSLEAqVAHADQQLRElgKFQVASDALKSREPQAKPQLDLS 1723
Cdd:NF012221 1793 KAYSVEG-VAEPGSHINP--DSPAAADGRFSEGLTEQEQEALE 1832
alph_xenorhab_A NF033928
alpha-xenorhabdolysin family binary toxin subunit A; Alpha-xenorhabdolysin was the founding ...
 266-522 2.86e-03

alpha-xenorhabdolysin family binary toxin subunit A; Alpha-xenorhabdolysin was the founding member of a family of alpha-helical pore-forming binary toxins. YaxAB from Yersinia enterocolitica has been studied structurally. This HMM represents subunit A proteins such as XaxA and YaxA, capable of binding to the membrane even in the absence of the B subunit. This family is related to the Bacillus haemolytic enterotoxin family (see PF05791.9), although thresholds for this HMM are set to exclude that family.


Pssm-ID: 468250 [Multi-domain]  Cd Length: 340  Bit Score: 42.29  E-value: 2.86e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 861483604  266 EKQAASPLEPRELEELRG--KNESLTFRLHE--TLKQCQDLKTEKGQMDRKINQLSEENGDLSFKLREFASNLQ------ 335
Cdd:NF033928   35 PKDGIPGLEPKDLLDLFQniRNHARSWSNLEpkIKQLANDLANYARNIVVTGNPIIDLINEMPIIKRGDLTEEElselpp 114

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 861483604  336 ------------QLQGALNEL---TEEHSKATQQWVEK----QAHLEKELSTALQDKKCLEEKN------EILQGKLSQL 390
Cdd:NF033928  115 iplssddkeivkELKEILEDLkndIKDYQQKADDVKKElddfENDLREELLPQLKLKKKLYDDNlgsdsiEELREKIDQL 194

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 861483604  391 EERLAQLPESPRQEKGEVLGDVLQL----------ESLKQEAAtlatnntqlQARVEMLENEQGQKEAQLlgershfeEE 460
Cdd:NF033928  195 EKEIEQLNKEYDDYVKLSFTGLAGGpiglaitggiFGSKAEKI---------RKEKNALIQEIDELQEQL--------KK 257

                         250       260       270       280       290       300
                  ....*....|....*....|....*....|....*....|....*....|....*....|..
gi 861483604  461 KQQLASLITNLQSSISNLSQAKEELEQASQaqgaKLNAQVASLTAELTTLSATLQQQDQELA 522
Cdd:NF033928  258 KNALLGSLERLQTSLDDILTRMEDALPALK----KLKGVWQSLLTDIDSSINALKEIDDADS 315
MARTX_Nterm NF012221
MARTX multifunctional-autoprocessing repeats-in-toxin holotoxin N-terminal region; This model ...
 772-1123 4.92e-03

MARTX multifunctional-autoprocessing repeats-in-toxin holotoxin N-terminal region; This model describes the N-terminal 1900 amino acids of MARTX family multifunctional-autoprocessing repeats-in-toxin holotoxins, which contain both repeat regions that facilitate their entry into eukaryotic target cells, and multiple effector domains.


Pssm-ID: 467957 [Multi-domain]  Cd Length: 1848  Bit Score: 42.13  E-value: 4.92e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 861483604  772 QQLAETHQAETKALRQELAKARTSNNMAEREVellvkevkTWR-KRYEDSQQGETQYglQEQLTTLKEEYEKSCQELRET 850
Cdd:NF012221 1452 QDLSNLTAGEVIALSFDFARRAGLSTNNGIEV--------LWNgEVVFASSGDASAW--QQKTLKLTAKAGSNRLEFKGT 1521

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 861483604  851 KEK------MAGIEAHSEL-QIGQHQSELAQLHANLARALQQVQEKENRAQKLADDLstlQEKMAATSKEVARLEALVRK 923
Cdd:NF012221 1522 GHNdglgyiLDNVVATSESsQQADAVSKHAKQDDAAQNALADKERAEADRQRLEQEK---QQQLAAISGSQSQLESTDQN 1598

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 861483604  924 A----GEQQETASLE-------LLKEPPKTRD--RESEWVEEQQGQQLcSTQAALRAMEREAEQM-------GTELEKLR 983
Cdd:NF012221 1599 AletnGQAQRDAILEesravtkELTTLAQGLDalDSQATYAGESGDQW-RNPFAGGLLDRVQEQLddakkisGKQLADAK 1677

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 861483604  984 AALMESQGQQQEERGQQEREVARLTQERGQAEADLAlekAAKAELEMRLQNALNEQQ-AEFANLQEALSRALSEKEGkDQ 1062
Cdd:NF012221 1678 QRHVDNQQKVKDAVAKSEAGVAQGEQNQANAEQDID---DAKADAEKRKDDALAKQNeAQQAESDANAAANDAQSRG-EQ 1753

                         330       340       350       360       370       380
                  ....*....|....*....|....*....|....*....|....*....|....*....|.
gi 861483604 1063 ElSKLCEQEAVQrmelkellqtvEQLKAQLAKKEKEQQQSARGASGENASGMGTQSEAVGK 1123
Cdd:NF012221 1754 D-ASAAENKANQ-----------AQADAKGAKQDESDKPNRQGAAGSGLSGKAYSVEGVAE 1802
MARTX_Nterm NF012221
MARTX multifunctional-autoprocessing repeats-in-toxin holotoxin N-terminal region; This model ...
 253-642 7.82e-03

MARTX multifunctional-autoprocessing repeats-in-toxin holotoxin N-terminal region; This model describes the N-terminal 1900 amino acids of MARTX family multifunctional-autoprocessing repeats-in-toxin holotoxins, which contain both repeat regions that facilitate their entry into eukaryotic target cells, and multiple effector domains.


Pssm-ID: 467957 [Multi-domain]  Cd Length: 1848  Bit Score: 41.74  E-value: 7.82e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 861483604  253 MMQQRIDRLALLNEKQAASPLEpRELEELRGKNESLTFRLHETLKQCQDLK-TEKGQMDRKINQLSEENGDLSFKLREFA 331
Cdd:NF012221 1457 LTAGEVIALSFDFARRAGLSTN-NGIEVLWNGEVVFASSGDASAWQQKTLKlTAKAGSNRLEFKGTGHNDGLGYILDNVV 1535

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 861483604  332 --SNLQQLQGALNELTEEhSKATQQwvekqahlekelstALQDKKCLEEKNEIL-QGKLSQLEE---RLAQLpESPRQEK 405
Cdd:NF012221 1536 atSESSQQADAVSKHAKQ-DDAAQN--------------ALADKERAEADRQRLeQEKQQQLAAisgSQSQL-ESTDQNA 1599

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 861483604  406 GEVLGDVlQLESLKQEAATLATNNTQLQARVEMLeNEQGQKEAQLlGE--RSHF------------EEEKQQLASLITNL 471
Cdd:NF012221 1600 LETNGQA-QRDAILEESRAVTKELTTLAQGLDAL-DSQATYAGES-GDqwRNPFagglldrvqeqlDDAKKISGKQLADA 1676

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 861483604  472 QSSIS-NLSQAKEELEQ--ASQAQGAKLNAQV------ASLTAELTTLSATLQQQDQELAGLKQQAQKKQAQLAQSLQQQ 542
Cdd:NF012221 1677 KQRHVdNQQKVKDAVAKseAGVAQGEQNQANAeqdiddAKADAEKRKDDALAKQNEAQQAESDANAAANDAQSRGEQDAS 1756

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 861483604  543 EQASQGlrHQVEQLSGSLKQKEKqleeaarelDASRRDHAQqlATAAKAQETSLRERDAACQQLEALEKEKAAKL--EIL 620
Cdd:NF012221 1757 AAENKA--NQAQADAKGAKQDES---------DKPNRQGAA--GSGLSGKAYSVEGVAEPGSHINPDSPAAADGRfsEGL 1823

                         410       420
                  ....*....|....*....|..
gi 861483604  621 QQQLQaanEAQDSAQNSVTQAQ 642
Cdd:NF012221 1824 TEQEQ---EALEGATNAVNRLQ 1842
 
Name Accession Description Interval E-value
HkD_NuMA cd22224
Hook domain found in nuclear mitotic apparatus protein (NuMA) and similar proteins; NuMA, also ...
 6-152 2.51e-50

Hook domain found in nuclear mitotic apparatus protein (NuMA) and similar proteins; NuMA, also called nuclear mitotic apparatus protein 1, or nuclear matrix protein-22 (NMP-22), or SP-H antigen, is a microtubule (MT)-binding protein that plays a role in the formation and maintenance of the spindle poles, and the alignment and segregation of chromosomes during mitotic cell division. The model corresponds to the N-terminal conserved globular Hook domain of NuMA, which folds as a variant of the helical calponin homology (CH) domain. It directly binds dynein light intermediate chains LIC1 and LIC2 through a conserved hydrophobic patch shared among other Hook adaptors.


Pssm-ID: 411795  Cd Length: 148  Bit Score: 175.07  E-value: 2.51e-50
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 861483604    6 TRAAALLSWVNSLRVADLVEAVPQLQDCSVFIKIIDGIRGTEEGQQILQQPVPERLDFVCSFLQKNRKRPSSPECLVSMQ 85
Cdd:cd22224     2 TKAEALLSWVNSLKLDDPIESISQLQDGTILLKIIYKLKGEEEEEQILDLSVEERLEFISSFLEGDCRFNSSQGTLVSWQ 81

                          90       100       110       120       130       140
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 861483604   86 KVMEG--SELELAKIIMLLLYHSSMSsqNLRDWEQFEYRIQAELAVILKFMLDHEDGLNLTEDLEIFLQ 152
Cdd:cd22224    82 KILQGenLELELAKVLLLLLYHSMMN--NNLTLEKLDYKTELELASILRFVLDNEDGLYLSEGLDKFLT 148
NuMA_LGNBD cd22298
LGN binding domain (LGNBD) of nuclear mitotic apparatus protein (NuMA) and similar proteins; ...
 1872-1930 3.49e-27

LGN binding domain (LGNBD) of nuclear mitotic apparatus protein (NuMA) and similar proteins; NuMA, also called nuclear matrix protein-22 (NMP-22), nuclear mitotic apparatus protein 1 (NUMA1), or SP-H antigen, is a microtubule (MT)-binding protein that plays a role in the formation and maintenance of spindle poles and the alignment and segregation of chromosomes during mitotic cell division. It is involved in the establishment of mitotic spindle orientation during metaphase, and elongation during anaphase in a dynein-dynactin-dependent manner. NuMA, in complex with LGN, forms NuMA:LGN hetero-hexamers that promote spindle orientation. The model corresponds to the LGN binding domain (LGNBD) of NuMA. LGN (named for leu-gly-asn repeats) is also known as G protein signaling modulator 2.


Pssm-ID: 412093  Cd Length: 56  Bit Score: 105.76  E-value: 3.49e-27
                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|....*....
gi 861483604 1872 LLSLPGYRPTTRSSTRRSQagvSSGAPPGRNSFYMGTCQDEPEQLDDWNRIAELQQRNR 1930
Cdd:cd22298     1 LLSLPGYRPSTRSSTRRSQ---SSSATGGRSTFYMGTCQDEPEHLDDWNRIAELQQRNR 56
SMC_prok_B TIGR02168
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...
 553-1329 2.53e-23

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274008 [Multi-domain]  Cd Length: 1179  Bit Score: 108.61  E-value: 2.53e-23
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 861483604   553 VEQLSGSLKQKEKQLEEA--ARELDASRRDHAQQLATA-AKAQETSLRERDAACQQLEALEKEKAAKLEILQQQLQAANE 629
Cdd:TIGR02168  195 LNELERQLKSLERQAEKAerYKELKAELRELELALLVLrLEELREELEELQEELKEAEEELEELTAELQELEEKLEELRL 274

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 861483604   630 AQDSAQNSVTQAQREKAELSQKVEELHALIEAAHQEQCEAQTQVAALEARLKAEQQKateREKVAQEKAQLQEQLWSLEE 709
Cdd:TIGR02168  275 EVSELEEEIEELQKELYALANEISRLEQQKQILRERLANLERQLEELEAQLEELESK---LDELAEELAELEEKLEELKE 351

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 861483604   710 SLKITKGSLEEEKCRAAAA---LEEHQHHISEMEAESRSLAEQHKQERKELEEekakrrgLGVQLQQLAEtHQAETKALR 786
Cdd:TIGR02168  352 ELESLEAELEELEAELEELesrLEELEEQLETLRSKVAQLELQIASLNNEIER-------LEARLERLED-RRERLQQEI 423

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 861483604   787 QELAKARTSNNMAE--REVELLVKEVKTWRKRYEDsqqgetqygLQEQLTTLKEEYEKSCQELRETKEKMAgieahselQ 864
Cdd:TIGR02168  424 EELLKKLEEAELKElqAELEELEEELEELQEELER---------LEEALEELREELEEAEQALDAAERELA--------Q 486

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 861483604   865 IGQHQSELAQLHANLARALQQVQEKENRAQKLADDLSTLQEKMAATSKEVARLEALVRKA-------GEQQETASLELLK 937
Cdd:TIGR02168  487 LQARLDSLERLQENLEGFSEGVKALLKNQSGLSGILGVLSELISVDEGYEAAIEAALGGRlqavvveNLNAAKKAIAFLK 566

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 861483604   938 EPPKTRDRESEwVEEQQGQQLCSTQAALRAMEREAEQMGTELEKLRAALmesqgqqqeergqQEREVARLTQERGQAEAD 1017
Cdd:TIGR02168  567 QNELGRVTFLP-LDSIKGTEIQGNDREILKNIEGFLGVAKDLVKFDPKL-------------RKALSYLLGGVLVVDDLD 632

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 861483604  1018 LALEKAAKAELEMRL----------QNALNEQQAEFANLQEALSRALSEKEgkdQELSKLCEQEAVQRMELKELLQTVEQ 1087
Cdd:TIGR02168  633 NALELAKKLRPGYRIvtldgdlvrpGGVITGGSAKTNSSILERRREIEELE---EKIEELEEKIAELEKALAELRKELEE 709

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 861483604  1088 LKAQLAKKEKEQQQSARGASGENASgmgtQSEAVGKMEALRAKVSKLEQQCQQQQEEADSLARSLESERAFHVERDRALE 1167
Cdd:TIGR02168  710 LEEELEQLRKELEELSRQISALRKD----LARLEAEVEQLEERIAQLSKELTELEAEIEELEERLEEAEEELAEAEAEIE 785

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 861483604  1168 TLQGQLEEKARELGYSQAASASAQRELATLRAKAQDHSKAEEEWKAQVARGQQEAVRKGSLISSLEEEVSILNRQVLEKE 1247
Cdd:TIGR02168  786 ELEAQIEQLKEELKALREALDELRAELTLLNEEAANLRERLESLERRIAATERRLEDLEEQIEELSEDIESLAAEIEELE 865

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 861483604  1248 GESKELKRLVIAESEKSQKLEERLRLL--QMETASNSARAAE-RSSALREEVQSLREEVEKQRAASENLRQELASQAERA 1324
Cdd:TIGR02168  866 ELIEELESELEALLNERASLEEALALLrsELEELSEELRELEsKRSELRRELEELREKLAQLELRLEGLEVRIDNLQERL 945


                   ....*
gi 861483604  1325 EELGQ 1329
Cdd:TIGR02168  946 SEEYS 950
Smc COG1196
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ...
 471-1052 6.35e-23

Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 440809 [Multi-domain]  Cd Length: 983  Bit Score: 107.33  E-value: 6.35e-23
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 861483604  471 LQSSISNLSQAKEELEQAsQAQGAKLNAQVASLTAELTTLSATLQQQDQELAGLKQQAQKKQAQLAQSLQQQEQASQGLR 550
Cdd:COG1196   227 AELLLLKLRELEAELEEL-EAELEELEAELEELEAELAELEAELEELRLELEELELELEEAQAEEYELLAELARLEQDIA 305

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 861483604  551 HQVEQLSgSLKQKEKQLEEAARELDASRRDHAQQLATAAKAQEtslrERDAACQQLEALEKEKAAKLEILQQQLQAANEA 630
Cdd:COG1196   306 RLEERRR-ELEERLEELEEELAELEEELEELEEELEELEEELE----EAEEELEEAEAELAEAEEALLEAEAELAEAEEE 380

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 861483604  631 QDSAQNSVTQAQREKAELSQKVEELHALIEAAHQEQCEAQTQVAALEARLKAEQQKATEREKVAQEKAQLQEQlwslees 710
Cdd:COG1196   381 LEELAEELLEALRAAAELAAQLEELEEAEEALLERLERLEEELEELEEALAELEEEEEEEEEALEEAAEEEAE------- 453

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 861483604  711 lkitkgsLEEEKCRAAAALEEHQhhisemeaESRSLAEQHKQERKELEEEKAKRRGLGVQLQQLAETHQAETKALRQELA 790
Cdd:COG1196   454 -------LEEEEEALLELLAELL--------EEAALLEAALAELLEELAEAAARLLLLLEAEADYEGFLEGVKAALLLAG 518

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 861483604  791 KARtsnnmaereVELLVKEVKTWRKRYEDSQQGETQYGLQEQLTTLKE------EYEKSCQELRETKEKMAGIEAHSELQ 864
Cdd:COG1196   519 LRG---------LAGAVAVLIGVEAAYEAALEAALAAALQNIVVEDDEvaaaaiEYLKAAKAGRATFLPLDKIRARAALA 589

                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 861483604  865 IGQHQSELAQLHANLARALQQVQEKENRAQKLADDLSTLQEKMAATSKEVARLEALVRKAGEQQETASLELLKEPPKTRD 944
Cdd:COG1196   590 AALARGAIGAAVDLVASDLREADARYYVLGDTLLGRTLVAARLEAALRRAVTLAGRLREVTLEGEGGSAGGSLTGGSRRE 669

                         490       500       510       520       530       540       550       560
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 861483604  945 R-ESEWVEEQQGQQLCSTQAALRAMEREAEQMGTELEKLRAALMESQGQQQEERGQQEREVARLTQERGQAEADLALEKA 1023
Cdd:COG1196   670 LlAALLEAEAELEELAERLAEEELELEEALLAEEEEERELAEAEEERLEEELEEEALEEQLEAEREELLEELLEEEELLE 749

                         570       580
                  ....*....|....*....|....*....
gi 861483604 1024 AKAELEMRLQNALNEQQAEFANLQEALSR 1052
Cdd:COG1196   750 EEALEELPEPPDLEELERELERLEREIEA 778
SMC_prok_B TIGR02168
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...
 209-935 5.84e-22

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274008 [Multi-domain]  Cd Length: 1179  Bit Score: 104.37  E-value: 5.84e-22
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 861483604   209 LQTPQFQMRRLKKQLADERNNRDELELELAEHRKLLTEKDAQISMMQQRIDRL-ALLNEKQAASPLEPRELEELRGKNES 287
Cdd:TIGR02168  241 LEELQEELKEAEEELEELTAELQELEEKLEELRLEVSELEEEIEELQKELYALaNEISRLEQQKQILRERLANLERQLEE 320

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 861483604   288 LTFRLHETLKQCQDLKTEKGQMDRKINQLSEENGDLSFKLREFASNLQQLQGALNELTEEH---SKATQQWVEKQAHLEK 364
Cdd:TIGR02168  321 LEAQLEELESKLDELAEELAELEEKLEELKEELESLEAELEELEAELEELESRLEELEEQLetlRSKVAQLELQIASLNN 400

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 861483604   365 ELSTALQDKKCLEEKNEILQgklSQLEERLAQLPESPRQEKGEvlgdvlQLESLKQEAATLATNNTQLQARVEMLENEQG 444
Cdd:TIGR02168  401 EIERLEARLERLEDRRERLQ---QEIEELLKKLEEAELKELQA------ELEELEEELEELQEELERLEEALEELREELE 471

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 861483604   445 QKEAQLLGERSHFEEEKQQLASLiTNLQSSISNLSQAKEELEQAsQAQGAKLNAQVASL--------TAELTTLSATLQQ 516
Cdd:TIGR02168  472 EAEQALDAAERELAQLQARLDSL-ERLQENLEGFSEGVKALLKN-QSGLSGILGVLSELisvdegyeAAIEAALGGRLQA 549

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 861483604   517 ---QDQELAGLKQQAQKKQAQLAQS----LQQQEQASQGLRHQVEQLSGSLKQKEKQLEEAARELDASRRDHAQQLATAa 589
Cdd:TIGR02168  550 vvvENLNAAKKAIAFLKQNELGRVTflplDSIKGTEIQGNDREILKNIEGFLGVAKDLVKFDPKLRKALSYLLGGVLVV- 628

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 861483604   590 kaqeTSLRERDAACQQLEALEKEKAAKLEILQQQlQAANEAQDSAQNSVTQAQREKAELSQKVEELHALIEAAHQEQCEA 669
Cdd:TIGR02168  629 ----DDLDNALELAKKLRPGYRIVTLDGDLVRPG-GVITGGSAKTNSSILERRREIEELEEKIEELEEKIAELEKALAEL 703

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 861483604   670 QTQVAALEarlkaeqqkaTEREKVAQEKAQLQEQLWSLEESLKItkgsLEEEKCRAAAALEEHQHHISEMEAESRSLAEQ 749
Cdd:TIGR02168  704 RKELEELE----------EELEQLRKELEELSRQISALRKDLAR----LEAEVEQLEERIAQLSKELTELEAEIEELEER 769

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 861483604   750 HKQERKELEEEKAKRrglgVQLQQLAETHQAETKALRQELAKARtsnnmaerevellvKEVKTWRKRYEDSQQGetqygl 829
Cdd:TIGR02168  770 LEEAEEELAEAEAEI----EELEAQIEQLKEELKALREALDELR--------------AELTLLNEEAANLRER------ 825

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 861483604   830 QEQLTTLKEEYEKSCQELRETKEKMAGIEAHSELQIGQHQSELAQLHANLARALQQVQEKENRAQKLADDLSTLQEKMAA 909
Cdd:TIGR02168  826 LESLERRIAATERRLEDLEEQIEELSEDIESLAAEIEELEELIEELESELEALLNERASLEEALALLRSELEELSEELRE 905

                          730       740
                   ....*....|....*....|....*.
gi 861483604   910 TSKEVARLEALVRKAGEQQETASLEL 935
Cdd:TIGR02168  906 LESKRSELRRELEELREKLAQLELRL 931
SMC_prok_B TIGR02168
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...
 302-1081 2.11e-21

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274008 [Multi-domain]  Cd Length: 1179  Bit Score: 102.44  E-value: 2.11e-21
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 861483604   302 LKTEKGQMDRKINQLSEENGDLSFKLREFASNLQQLQGALNELTEEHSKATqqwvEKQAHLEKELSTALQDKKCLEEKNE 381
Cdd:TIGR02168  230 LVLRLEELREELEELQEELKEAEEELEELTAELQELEEKLEELRLEVSELE----EEIEELQKELYALANEISRLEQQKQ 305

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 861483604   382 ILQGKLSQLEERLAQLPESPRQEKGEVLGDVLQLESLKQEAATLATNNTQLQARVEMLENEQGQKEAQLLGERSHFEEEK 461
Cdd:TIGR02168  306 ILRERLANLERQLEELEAQLEELESKLDELAEELAELEEKLEELKEELESLEAELEELEAELEELESRLEELEEQLETLR 385

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 861483604   462 QQLASLITNLQSSISNLSQAKEELEQasqaqgakLNAQVASLTAELTTLSATLQQQD-QELAGLKQQAQKKQAQLAQSLQ 540
Cdd:TIGR02168  386 SKVAQLELQIASLNNEIERLEARLER--------LEDRRERLQQEIEELLKKLEEAElKELQAELEELEEELEELQEELE 457

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 861483604   541 QQEQASQGLRHQVEQLSGSLKQKEKQLEEAARELDASRR------DHAQQLATAAKAQETSLRERDAACQQLEALEKEKA 614
Cdd:TIGR02168  458 RLEEALEELREELEEAEQALDAAERELAQLQARLDSLERlqenleGFSEGVKALLKNQSGLSGILGVLSELISVDEGYEA 537

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 861483604   615 AKLEILQQQLQAA----NEAQDSAQNSVTQAQREKAELSQKVEELHALIEAAHQEQCEAQTQVAALEARL---KAEQQKA 687
Cdd:TIGR02168  538 AIEAALGGRLQAVvvenLNAAKKAIAFLKQNELGRVTFLPLDSIKGTEIQGNDREILKNIEGFLGVAKDLvkfDPKLRKA 617

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 861483604   688 TE----REKVAQEKAQLQEQLWSLEESLKITkgSLEEEKCRAAAAleehqhhISEMEAESRSLAEQHKQERKELEEEKAK 763
Cdd:TIGR02168  618 LSyllgGVLVVDDLDNALELAKKLRPGYRIV--TLDGDLVRPGGV-------ITGGSAKTNSSILERRREIEELEEKIEE 688

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 861483604   764 RRGLGVQLQQLAETHQAETKALRQELAKARTSNNMAEREVELLVKEVKTWRKRYED-----SQQGETQYGLQEQLTTLKE 838
Cdd:TIGR02168  689 LEEKIAELEKALAELRKELEELEEELEQLRKELEELSRQISALRKDLARLEAEVEQleeriAQLSKELTELEAEIEELEE 768

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 861483604   839 EYEKSCQELRETKEKMAGIEAhselQIGQHQSELAQLHANLARALQQVQEKENRAQKLADDLSTLQEKMAATSKEVARLE 918
Cdd:TIGR02168  769 RLEEAEEELAEAEAEIEELEA----QIEQLKEELKALREALDELRAELTLLNEEAANLRERLESLERRIAATERRLEDLE 844

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 861483604   919 ALVRKAGEQQETASLELLKEPPKTRDRESEWVEEQqgQQLCSTQAALRAMEREAEQMGTELEKLRAALMEsqgqqqeerg 998
Cdd:TIGR02168  845 EQIEELSEDIESLAAEIEELEELIEELESELEALL--NERASLEEALALLRSELEELSEELRELESKRSE---------- 912

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 861483604   999 qqerevarLTQERGQAEADLALEKAAKAELEMRLQNalneQQAEFANLQEALSRALSEKEGKDQELSKLCEQEAVQ-RME 1077
Cdd:TIGR02168  913 --------LRRELEELREKLAQLELRLEGLEVRIDN----LQERLSEEYSLTLEEAEALENKIEDDEEEARRRLKRlENK 980


                   ....
gi 861483604  1078 LKEL 1081
Cdd:TIGR02168  981 IKEL 984
PTZ00121 PTZ00121
MAEBL; Provisional
 1006-1724 2.26e-21

MAEBL; Provisional


Pssm-ID: 173412 [Multi-domain]  Cd Length: 2084  Bit Score: 102.53  E-value: 2.26e-21
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 861483604 1006 RLTQERGQAEADLALEKAAKAELEMRLQNALNEQQAEFANLQEALSRALSEKEGKDQELSKLCEQ----EAVQRME---- 1077
Cdd:PTZ00121 1110 KAEEARKAEEAKKKAEDARKAEEARKAEDARKAEEARKAEDAKRVEIARKAEDARKAEEARKAEDakkaEAARKAEevrk 1189

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 861483604 1078 LKELLQTVEQLKAQLAKKEKEQQ--QSARGASGENASGMGTQSEAVGKMEALRAKVSKLEQQCQQQQEEADSLARSLESE 1155
Cdd:PTZ00121 1190 AEELRKAEDARKAEAARKAEEERkaEEARKAEDAKKAEAVKKAEEAKKDAEEAKKAEEERNNEEIRKFEEARMAHFARRQ 1269

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 861483604 1156 RAFHVERDRALETLQGQLEEKARElgysQAASASAQRELATLRAKAQDHSKAEE-EWKAQVARGQQEAVRKGSLISSLEE 1234
Cdd:PTZ00121 1270 AAIKAEEARKADELKKAEEKKKAD----EAKKAEEKKKADEAKKKAEEAKKADEaKKKAEEAKKKADAAKKKAEEAKKAA 1345

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 861483604 1235 EVSILNRQVLEKEGESKELKrlviAESEKSQKLEERLRLLQMETASNSARAAERSSALREEVQSLREEVEKQRAASEnlr 1314
Cdd:PTZ00121 1346 EAAKAEAEAAADEAEAAEEK----AEAAEKKKEEAKKKADAAKKKAEEKKKADEAKKKAEEDKKKADELKKAAAAKK--- 1418

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 861483604 1315 qelasQAERAEELGQELKAWQEKFFQKEQALSALQLEHTSTQALVSELLP--AKHLCQQLQAEQVAAEKRHREELEQSKQ 1392
Cdd:PTZ00121 1419 -----KADEAKKKAEEKKKADEAKKKAEEAKKADEAKKKAEEAKKAEEAKkkAEEAKKADEAKKKAEEAKKADEAKKKAE 1493

                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 861483604 1393 AAGGLRTELMRAQRELGELVPLRQkvAEQERAAQQLR-AEKASYAEQLsmlKKAHGLLAEENRGLGERANLGRQFLEVEl 1471
Cdd:PTZ00121 1494 EAKKKADEAKKAAEAKKKADEAKK--AEEAKKADEAKkAEEAKKADEA---KKAEEKKKADELKKAEELKKAEEKKKAE- 1567

                         490       500       510       520       530       540       550       560
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 861483604 1472 dQAREKYIQELAAVRGDAETRLAEMR--QEVQSTTHELEVMTA----KYEGAKVKVlEERQRFQEERQKltaqVEQLEVF 1545
Cdd:PTZ00121 1568 -EAKKAEEDKNMALRKAEEAKKAEEAriEEVMKLYEEEKKMKAeeakKAEEAKIKA-EELKKAEEEKKK----VEQLKKK 1641

                         570       580       590       600       610       620       630       640
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 861483604 1546 QREQTKKVEELSKKladyDQASKVQQQKLKafqaqggesqQEAQRLQTQLNELQVQLSQKEQAAEHYKVQMEKAKTHYDA 1625
Cdd:PTZ00121 1642 EAEEKKKAEELKKA----EEENKIKAAEEA----------KKAEEDKKKAEEAKKAEEDEKKAAEALKKEAEEAKKAEEL 1707

                         650       660       670       680       690       700       710       720
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 861483604 1626 KKQQNQELQEQlqglEQLQKENKELRAEAERLGQELQQAGLKTKEA--EQTCRHLTAQVRSLEAQVAHADQQLRElgkfQ 1703
Cdd:PTZ00121 1708 KKKEAEEKKKA----EELKKAEEENKIKAEEAKKEAEEDKKKAEEAkkDEEEKKKIAHLKKEEEKKAEEIRKEKE----A 1779

                         730       740
                  ....*....|....*....|.
gi 861483604 1704 VASDALKSREPQAKPQLDLSI 1724
Cdd:PTZ00121 1780 VIEEELDEEDEKRRMEVDKKI 1800
PTZ00121 PTZ00121
MAEBL; Provisional
 572-1330 1.45e-20

MAEBL; Provisional


Pssm-ID: 173412 [Multi-domain]  Cd Length: 2084  Bit Score: 99.83  E-value: 1.45e-20
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 861483604  572 RELDASRRDHAQQLATAAKAQETSLRERDAACQQLEALEKEKAAKLEILQQQLQAANEAQDSAQNSVTQAQRE------- 644
Cdd:PTZ00121 1045 KDIIDEDIDGNHEGKAEAKAHVGQDEGLKPSYKDFDFDAKEDNRADEATEEAFGKAEEAKKTETGKAEEARKAeeakkka 1124

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 861483604  645 ----KAELSQKVEELHALIEAAHQEQCEAQTQVAALEARLKAEQQKATEREKVAQEKAQLQE-----QLWSLEESLKITK 715
Cdd:PTZ00121 1125 edarKAEEARKAEDARKAEEARKAEDAKRVEIARKAEDARKAEEARKAEDAKKAEAARKAEEvrkaeELRKAEDARKAEA 1204

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 861483604  716 GSLEEEKCRAaaalEEHQHHISEMEAESRSLAEQHK---QERKELEEEKAKRRGLGVQLQQLAE------THQAETKALR 786
Cdd:PTZ00121 1205 ARKAEEERKA----EEARKAEDAKKAEAVKKAEEAKkdaEEAKKAEEERNNEEIRKFEEARMAHfarrqaAIKAEEARKA 1280

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 861483604  787 QELAKARTSNNMAEREVELLVKEVKTWRKRYEDSQQGETQYGLQEQLTTLKEEYEKSCQELRETKE--KMAGIEAHSELQ 864
Cdd:PTZ00121 1281 DELKKAEEKKKADEAKKAEEKKKADEAKKKAEEAKKADEAKKKAEEAKKKADAAKKKAEEAKKAAEaaKAEAEAAADEAE 1360

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 861483604  865 IGQHQSELAQLHANLARALQQVQEKENRAQKLADDLSTLQEKMAATSKEVARLEALVRKAGEQQETASLELLKEPPKTRD 944
Cdd:PTZ00121 1361 AAEEKAEAAEKKKEEAKKKADAAKKKAEEKKKADEAKKKAEEDKKKADELKKAAAAKKKADEAKKKAEEKKKADEAKKKA 1440

                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 861483604  945 RESEWVEE--QQGQQLCSTQAALRAME--REAEQMGTELEKLRAAlmESQGQQQEERGQQEREVARLTQERGQAEADLAL 1020
Cdd:PTZ00121 1441 EEAKKADEakKKAEEAKKAEEAKKKAEeaKKADEAKKKAEEAKKA--DEAKKKAEEAKKKADEAKKAAEAKKKADEAKKA 1518

                         490       500       510       520       530       540       550       560
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 861483604 1021 EKAAKAElemRLQNALNEQQAEFANLQEALSRAlsEKEGKDQELSKLCEQEAVQRMELKELLQTVEQLKAQLAKKEKEQQ 1100
Cdd:PTZ00121 1519 EEAKKAD---EAKKAEEAKKADEAKKAEEKKKA--DELKKAEELKKAEEKKKAEEAKKAEEDKNMALRKAEEAKKAEEAR 1593

                         570       580       590       600       610       620       630       640
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 861483604 1101 QSARGASGENASGMgtQSEAVGKMEALRAKVSKLeQQCQQQQEEADSLARSLESERAFHVERDRALETLQGQLEEKAREL 1180
Cdd:PTZ00121 1594 IEEVMKLYEEEKKM--KAEEAKKAEEAKIKAEEL-KKAEEEKKKVEQLKKKEAEEKKKAEELKKAEEENKIKAAEEAKKA 1670

                         650       660       670       680       690       700       710       720
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 861483604 1181 GYSQAASASAQRELATLRAKAQDHSKAEEEWKA--QVARGQQEAVRKGSLISSLEEEVSILNRQVLEKEGESKELKRLVI 1258
Cdd:PTZ00121 1671 EEDKKKAEEAKKAEEDEKKAAEALKKEAEEAKKaeELKKKEAEEKKKAEELKKAEEENKIKAEEAKKEAEEDKKKAEEAK 1750

                         730       740       750       760       770       780       790
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 861483604 1259 AESEKSQKLEErlrLLQMETASNSARAAERSSALREEVqslREEVEKQRAASENLRQELASQAERAEELGQE 1330
Cdd:PTZ00121 1751 KDEEEKKKIAH---LKKEEEKKAEEIRKEKEAVIEEEL---DEEDEKRRMEVDKKIKDIFDNFANIIEGGKE 1816
SMC_prok_B TIGR02168
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...
 745-1566 3.63e-20

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274008 [Multi-domain]  Cd Length: 1179  Bit Score: 98.21  E-value: 3.63e-20
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 861483604   745 SLAEQHKQERKELEEekAKRRGLGVQLQQLA---ETHQAETKALRQELAKARTSNNMAEREVELLVKEVKTWRKRYEDSQ 821
Cdd:TIGR02168  210 EKAERYKELKAELRE--LELALLVLRLEELReelEELQEELKEAEEELEELTAELQELEEKLEELRLEVSELEEEIEELQ 287

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 861483604   822 QG-ETQYGLQEQLTTLKEEYEKSCQELRETKEKMAGIEAHSELQIGQHQSELAQLHANLARALQQVQEKENRAQKLADDL 900
Cdd:TIGR02168  288 KElYALANEISRLEQQKQILRERLANLERQLEELEAQLEELESKLDELAEELAELEEKLEELKEELESLEAELEELEAEL 367

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 861483604   901 STLQEKMAATSKEVARLEALVRKAGEQQETASLELLK-EPPKTR--DRESEWVEEQQGQQLCSTQAALRAMEREAEQMGT 977
Cdd:TIGR02168  368 EELESRLEELEEQLETLRSKVAQLELQIASLNNEIERlEARLERleDRRERLQQEIEELLKKLEEAELKELQAELEELEE 447

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 861483604   978 ELEKLRAALmesqGQQQEERGQQEREVARLTQERGQAEADLALEKAAKAELEMRLQNALNEQQAEFANLQEAlsralSEK 1057
Cdd:TIGR02168  448 ELEELQEEL----ERLEEALEELREELEEAEQALDAAERELAQLQARLDSLERLQENLEGFSEGVKALLKNQ-----SGL 518

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 861483604  1058 EGKDQELSKLCEQEAVQRMELKELLQTVEQlkaQLAKKEKEQQQSARGASGENASGmgtqseAVGKMEALRAKVSKLEQQ 1137
Cdd:TIGR02168  519 SGILGVLSELISVDEGYEAAIEAALGGRLQ---AVVVENLNAAKKAIAFLKQNELG------RVTFLPLDSIKGTEIQGN 589

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 861483604  1138 CQQQQEEADSLARSLESERAFHVERDRALETLQGQL---------EEKARELGYSQA---------------ASASAQRE 1193
Cdd:TIGR02168  590 DREILKNIEGFLGVAKDLVKFDPKLRKALSYLLGGVlvvddldnaLELAKKLRPGYRivtldgdlvrpggviTGGSAKTN 669

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 861483604  1194 LATL--RAKAQDHSKAEEEWKAQVARGQQEAVRKGSLISSLEEEVSILNRQVLEKEGESKELKRLVIAESEKSQKLEERL 1271
Cdd:TIGR02168  670 SSILerRREIEELEEKIEELEEKIAELEKALAELRKELEELEEELEQLRKELEELSRQISALRKDLARLEAEVEQLEERI 749

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 861483604  1272 RLLQmetasnsaraaerssalrEEVQSLREEVEKQRAASENLRQELASQAERAEELGQELKAWQEKFFQKEQALSALQLE 1351
Cdd:TIGR02168  750 AQLS------------------KELTELEAEIEELEERLEEAEEELAEAEAEIEELEAQIEQLKEELKALREALDELRAE 811

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 861483604  1352 HTSTQALVSELLPAkhlCQQLQAEQVAAEKRHREELEQSKQAAGglrtELMRAQRELGElvpLRQKVAEQERAAQQLRAE 1431
Cdd:TIGR02168  812 LTLLNEEAANLRER---LESLERRIAATERRLEDLEEQIEELSE----DIESLAAEIEE---LEELIEELESELEALLNE 881

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 861483604  1432 KASYAEQLSMLKKAHGLLAEENRGLGERANLGRQFLEvELDQAREKYIQELAAVRGDAETRLAEMRQEVQSTtheLEVMT 1511
Cdd:TIGR02168  882 RASLEEALALLRSELEELSEELRELESKRSELRRELE-ELREKLAQLELRLEGLEVRIDNLQERLSEEYSLT---LEEAE 957

                          810       820       830       840       850
                   ....*....|....*....|....*....|....*....|....*....|....*....
gi 861483604  1512 AKYEGAKVKVLEERQRFQEERQKLTA----QVEQLEVFQrEQTKKVEELSKKLADYDQA 1566
Cdd:TIGR02168  958 ALENKIEDDEEEARRRLKRLENKIKElgpvNLAAIEEYE-ELKERYDFLTAQKEDLTEA 1015
Smc COG1196
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ...
 1123-1658 5.42e-20

Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 440809 [Multi-domain]  Cd Length: 983  Bit Score: 97.70  E-value: 5.42e-20
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 861483604 1123 KMEALRAKVSKLEQQCQQQQEEADSLARSLESERAFHVERDRALETLQGQLEEKARELG--------------YSQAASA 1188
Cdd:COG1196   240 ELEELEAELEELEAELEELEAELAELEAELEELRLELEELELELEEAQAEEYELLAELArleqdiarleerrrELEERLE 319

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 861483604 1189 SAQRELATLRAKAQDHSKAEEEWKAQVARGQQEAVRKGSLISSLEEEVSILNRQVLEKEGESKELKRLVIAESEKSQKLE 1268
Cdd:COG1196   320 ELEEELAELEEELEELEEELEELEEELEEAEEELEEAEAELAEAEEALLEAEAELAEAEEELEELAEELLEALRAAAELA 399

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 861483604 1269 ERLRLLQMETASNSARAAERSSALREEVQSLREEVEKQRAASENLRQELASQAERAEELGQELKAWQEKFFQKEQALSAL 1348
Cdd:COG1196   400 AQLEELEEAEEALLERLERLEEELEELEEALAELEEEEEEEEEALEEAAEEEAELEEEEEALLELLAELLEEAALLEAAL 479

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 861483604 1349 QLEHTSTQALVSELLPAKHLCQQLQAEQVAAEKRHREELEQSKQAAGGLR---TELMRAQRELGELVPLRQKVAEQERAA 1425
Cdd:COG1196   480 AELLEELAEAAARLLLLLEAEADYEGFLEGVKAALLLAGLRGLAGAVAVLigvEAAYEAALEAALAAALQNIVVEDDEVA 559

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 861483604 1426 QQ----LRAEKASYAEQLSMLKKAHGLLAEENRGLGERAnLGRQFLEVELDQAREKYIQELAAVRGDAETRLAEMRQEVQ 1501
Cdd:COG1196   560 AAaieyLKAAKAGRATFLPLDKIRARAALAAALARGAIG-AAVDLVASDLREADARYYVLGDTLLGRTLVAARLEAALRR 638

                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 861483604 1502 STTHELEVMTAKYEGAKVKVLEERQRFQEERQKLTAQVEQLEvfQREQTKKVEELSKKLADYDQASKVQQQKLKAFQAQG 1581
Cdd:COG1196   639 AVTLAGRLREVTLEGEGGSAGGSLTGGSRRELLAALLEAEAE--LEELAERLAEEELELEEALLAEEEEERELAEAEEER 716

                         490       500       510       520       530       540       550
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 861483604 1582 GESQQEAQRLQTQLNELQVQLSQKEQAAEHYKVQMEKAKTHYDAKkqqnqelqeqlqgLEQLQKENKELRAEAERLG 1658
Cdd:COG1196   717 LEEELEEEALEEQLEAEREELLEELLEEEELLEEEALEELPEPPD-------------LEELERELERLEREIEALG 780
SMC_prok_B TIGR02168
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...
 736-1560 7.70e-20

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274008 [Multi-domain]  Cd Length: 1179  Bit Score: 97.43  E-value: 7.70e-20
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 861483604   736 ISEMEAESRSLAEQHKQERKELEEEKAKRRglgVQLQQLAethqAETKALRQELAKARTSNNMAEREVELLVKEVKTWRK 815
Cdd:TIGR02168  195 LNELERQLKSLERQAEKAERYKELKAELRE---LELALLV----LRLEELREELEELQEELKEAEEELEELTAELQELEE 267

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 861483604   816 RYEDsqqgetqygLQEQLTTLKEEYEKSCQELRETKEKMAGIEAhselQIGQHQSELAQLHANLARALQQVQEKENRAQK 895
Cdd:TIGR02168  268 KLEE---------LRLEVSELEEEIEELQKELYALANEISRLEQ----QKQILRERLANLERQLEELEAQLEELESKLDE 334

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 861483604   896 LADDLSTLQEKMAATSKEVARLEALVRKAGEQQEtaslellkeppktrdrESEWVEEQQGQQLCSTQAALRAMEREAEQM 975
Cdd:TIGR02168  335 LAEELAELEEKLEELKEELESLEAELEELEAELE----------------ELESRLEELEEQLETLRSKVAQLELQIASL 398

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 861483604   976 GTELEKLRAALmesqgqqqeerGQQEREVARLTQERGQAEAdlALEKAAKAELEMRL---QNALNEQQAEFANLQEALSR 1052
Cdd:TIGR02168  399 NNEIERLEARL-----------ERLEDRRERLQQEIEELLK--KLEEAELKELQAELeelEEELEELQEELERLEEALEE 465

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 861483604  1053 ALSEKEGKDQELSKLCEQEAVQRMELkELLQTVEQLKAQLAKKEKEQQQSARGASGenasGMGTQSEAVGKMEALRAKVS 1132
Cdd:TIGR02168  466 LREELEEAEQALDAAERELAQLQARL-DSLERLQENLEGFSEGVKALLKNQSGLSG----ILGVLSELISVDEGYEAAIE 540

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 861483604  1133 K---------LEQQCQQQQEEADSLARSLESERAFHVERDRALETLQG-QLEEKARELGYSQAASasaqrELATLRAKAQ 1202
Cdd:TIGR02168  541 AalggrlqavVVENLNAAKKAIAFLKQNELGRVTFLPLDSIKGTEIQGnDREILKNIEGFLGVAK-----DLVKFDPKLR 615

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 861483604  1203 dhsKAEEEWKAQV--------ARGQQEAVRKGSLISSLEEEV-----------SILNRQVLEKEGESKELkrlviaeSEK 1263
Cdd:TIGR02168  616 ---KALSYLLGGVlvvddldnALELAKKLRPGYRIVTLDGDLvrpggvitggsAKTNSSILERRREIEEL-------EEK 685

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 861483604  1264 SQKLEERLRLLQMETAsnsaraaerssALREEVQSLREEVEKQRAASENLRQELASQAERAEELGQELKAWQEKFFQKEQ 1343
Cdd:TIGR02168  686 IEELEEKIAELEKALA-----------ELRKELEELEEELEQLRKELEELSRQISALRKDLARLEAEVEQLEERIAQLSK 754

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 861483604  1344 ALSALQLEHTSTQALVSELLPAKHLCQQLQAEQVAAEKRHREELEQSKQAAGGLRTELMRAQRELGELVP----LRQKVA 1419
Cdd:TIGR02168  755 ELTELEAEIEELEERLEEAEEELAEAEAEIEELEAQIEQLKEELKALREALDELRAELTLLNEEAANLRErlesLERRIA 834

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 861483604  1420 EQERAAQQLRAEKASYAEQLSMLKKAHG----LLAEENRGLGERANLgRQFLEVELDQAREKYiQELAAVRGDAETRLAE 1495
Cdd:TIGR02168  835 ATERRLEDLEEQIEELSEDIESLAAEIEeleeLIEELESELEALLNE-RASLEEALALLRSEL-EELSEELRELESKRSE 912

                          810       820       830       840       850       860
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 861483604  1496 MRQEVQSTTHELEVMTAKYEGAKVKVLEERQRFQEERQKLTAQVEQLEVFQREQTKKVEELSKKL 1560
Cdd:TIGR02168  913 LRRELEELREKLAQLELRLEGLEVRIDNLQERLSEEYSLTLEEAEALENKIEDDEEEARRRLKRL 977
SMC_prok_B TIGR02168
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...
 836-1658 1.17e-19

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274008 [Multi-domain]  Cd Length: 1179  Bit Score: 96.66  E-value: 1.17e-19
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 861483604   836 LKEEYEKSCQELRETKEKMAGIE-AHSELQigqHQSELAQLHANLARALQQVQEKENRAQK--LADDLSTLQEKMAATSK 912
Cdd:TIGR02168  170 YKERRKETERKLERTRENLDRLEdILNELE---RQLKSLERQAEKAERYKELKAELRELELalLVLRLEELREELEELQE 246

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 861483604   913 EVARLEALVRKAGEQQETASLELLKEPPKTRDRESEWVEEQQG-QQLCSTQAALRAMEREAEQMGTELEKLRAALMESQG 991
Cdd:TIGR02168  247 ELKEAEEELEELTAELQELEEKLEELRLEVSELEEEIEELQKElYALANEISRLEQQKQILRERLANLERQLEELEAQLE 326

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 861483604   992 QQQEERGQQEREVARLTQERGQAEADLALEKAAKAELEMRLQNALNEQQAEFANLqEALSRALSEKEgkdqelsklcEQE 1071
Cdd:TIGR02168  327 ELESKLDELAEELAELEEKLEELKEELESLEAELEELEAELEELESRLEELEEQL-ETLRSKVAQLE----------LQI 395

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 861483604  1072 AVQRMELKELLQTVEQLKAQLAKKEKEQQQSARGASGENASGMGTQSEAVGKM--------EALRAKVSKLEQQCQQQQE 1143
Cdd:TIGR02168  396 ASLNNEIERLEARLERLEDRRERLQQEIEELLKKLEEAELKELQAELEELEEEleelqeelERLEEALEELREELEEAEQ 475

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 861483604  1144 EADSLARSLESERAfhveRDRALETLQGQLEEKARELgysqAASASAQRELATLRAKAQDHSKAEEEWKA---------- 1213
Cdd:TIGR02168  476 ALDAAERELAQLQA----RLDSLERLQENLEGFSEGV----KALLKNQSGLSGILGVLSELISVDEGYEAaieaalggrl 547

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 861483604  1214 --------QVARGQQEAVRKGSLISSLEEEVSILNRQVLE---------KEGESKELKRLVIAESEKSQKLEERLRLLQM 1276
Cdd:TIGR02168  548 qavvvenlNAAKKAIAFLKQNELGRVTFLPLDSIKGTEIQgndreilknIEGFLGVAKDLVKFDPKLRKALSYLLGGVLV 627

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 861483604  1277 etASNSARAAERSSALREEVQSLREEVE--------------------KQRAASENLRQELASQAERAEELGQELKAWQE 1336
Cdd:TIGR02168  628 --VDDLDNALELAKKLRPGYRIVTLDGDlvrpggvitggsaktnssilERRREIEELEEKIEELEEKIAELEKALAELRK 705

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 861483604  1337 KFFQKEQALSALQLEHTSTQALVSELlpaKHLCQQLQAEQVAAEKRHREELEQSKQAAGGLRTELMRAQRELGELVPLRQ 1416
Cdd:TIGR02168  706 ELEELEEELEQLRKELEELSRQISAL---RKDLARLEAEVEQLEERIAQLSKELTELEAEIEELEERLEEAEEELAEAEA 782

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 861483604  1417 KVAEQERAAQQLRAEKASYAEQLSMLKKAHGLLAEENRGLGERAnlgrqfleveldQAREKYIQELAAVRGDAETRLAEM 1496
Cdd:TIGR02168  783 EIEELEAQIEQLKEELKALREALDELRAELTLLNEEAANLRERL------------ESLERRIAATERRLEDLEEQIEEL 850

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 861483604  1497 RQEVQSTTHELEVMTakyegakvkvlEERQRFQEERQKLTAQVEQLEVFQREQTKKVEELSKKLADYDqaskvqqQKLKA 1576
Cdd:TIGR02168  851 SEDIESLAAEIEELE-----------ELIEELESELEALLNERASLEEALALLRSELEELSEELRELE-------SKRSE 912

                          810       820       830       840       850       860       870       880
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 861483604  1577 FQAQGGESQQEAQRLQTQLNELQVQLSQ-KEQAAEHYKVQMEKAKTHYDAKKQQnqelqeqlqgLEQLQKENKELRAEAE 1655
Cdd:TIGR02168  913 LRRELEELREKLAQLELRLEGLEVRIDNlQERLSEEYSLTLEEAEALENKIEDD----------EEEARRRLKRLENKIK 982


                   ...
gi 861483604  1656 RLG 1658
Cdd:TIGR02168  983 ELG 985
Smc COG1196
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ...
 1004-1598 1.53e-19

Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 440809 [Multi-domain]  Cd Length: 983  Bit Score: 96.16  E-value: 1.53e-19
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 861483604 1004 VARLTQERGQAEADLALEKAAK-AELEMRLqNALNEQQAEFANLQEALSRALSEKEGKDQELSKLCEQEAVQRMELKELL 1082
Cdd:COG1196   202 LEPLERQAEKAERYRELKEELKeLEAELLL-LKLRELEAELEELEAELEELEAELEELEAELAELEAELEELRLELEELE 280

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 861483604 1083 QTVEQLKAQLAKKEKEQQQSARGasgenasgmgtqseavgkMEALRAKVSKLEQQCQQQQEEADSLARSLESERAFHVER 1162
Cdd:COG1196   281 LELEEAQAEEYELLAELARLEQD------------------IARLEERRRELEERLEELEEELAELEEELEELEEELEEL 342

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 861483604 1163 DRALETLQGQLEEKARELGYSQAASASAQRELATLRAKAQDHSKAEEEWKAQVARGQQEAVRKGSLISSLEEEVSILNRQ 1242
Cdd:COG1196   343 EEELEEAEEELEEAEAELAEAEEALLEAEAELAEAEEELEELAEELLEALRAAAELAAQLEELEEAEEALLERLERLEEE 422

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 861483604 1243 VLEKEGESKELKRLVIAESEKsqklEERLRLLQMETASNSARAAERSSALREEVQSLREEVEKQRAASENLRQELASQAE 1322
Cdd:COG1196   423 LEELEEALAELEEEEEEEEEA----LEEAAEEEAELEEEEEALLELLAELLEEAALLEAALAELLEELAEAAARLLLLLE 498

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 861483604 1323 RAEELGQELKAWQEKFFQKEQALSALQLEHTSTQALVSELLPAKHLCQQLQAEQVAAEKRHREELEQSKQAAGGLRTEL- 1401
Cdd:COG1196   499 AEADYEGFLEGVKAALLLAGLRGLAGAVAVLIGVEAAYEAALEAALAAALQNIVVEDDEVAAAAIEYLKAAKAGRATFLp 578

                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 861483604 1402 ---MRAQRELGELVPLRQKVAEQERAAQQLRAEKASYAEQLSMLKKAHGLLAEENRGLGERANLGRQFLEVELDQAREKY 1478
Cdd:COG1196   579 ldkIRARAALAAALARGAIGAAVDLVASDLREADARYYVLGDTLLGRTLVAARLEAALRRAVTLAGRLREVTLEGEGGSA 658

                         490       500       510       520       530       540       550       560
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 861483604 1479 IQELAAVRGDA-ETRLAEMRQEVQSTTHELEVMTAKYEGAKVKVLEERQRFQEERQKLTAQVEQLEVFQREQTKKVEELS 1557
Cdd:COG1196   659 GGSLTGGSRRElLAALLEAEAELEELAERLAEEELELEEALLAEEEEERELAEAEEERLEEELEEEALEEQLEAEREELL 738

                         570       580       590       600
                  ....*....|....*....|....*....|....*....|.
gi 861483604 1558 KKLADYDQASKVQQQKLKAFQAQGGESQQEAQRLQTQLNEL 1598
Cdd:COG1196   739 EELLEEEELLEEEALEELPEPPDLEELERELERLEREIEAL 779
PTZ00121 PTZ00121
MAEBL; Provisional
 562-1260 1.56e-19

MAEBL; Provisional


Pssm-ID: 173412 [Multi-domain]  Cd Length: 2084  Bit Score: 96.75  E-value: 1.56e-19
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 861483604  562 QKEKQLEEAARELDASRRDHAQQLATAAKAQEtsLRERDAACQQLEALEKEKAAKLEilqqQLQAANEAQDSAQNSVTQA 641
Cdd:PTZ00121 1161 EDARKAEEARKAEDAKKAEAARKAEEVRKAEE--LRKAEDARKAEAARKAEEERKAE----EARKAEDAKKAEAVKKAEE 1234

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 861483604  642 QREKAELSQKVEELHALIEAAHQEQCEaQTQVAALEARLKAEQQKATEREKVAQEKAQLQEqlwsleeslkiTKGSLEEE 721
Cdd:PTZ00121 1235 AKKDAEEAKKAEEERNNEEIRKFEEAR-MAHFARRQAAIKAEEARKADELKKAEEKKKADE-----------AKKAEEKK 1302

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 861483604  722 KCRAAAALEEHQHHISEMEAESRSLAEQHKQERKELEEEKAKrrglgvqlqqlAETHQAETKALRQELAKARTSNNMAER 801
Cdd:PTZ00121 1303 KADEAKKKAEEAKKADEAKKKAEEAKKKADAAKKKAEEAKKA-----------AEAAKAEAEAAADEAEAAEEKAEAAEK 1371

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 861483604  802 EVELLVKEVKTWRKRYEDSQQGetqyglqEQLTTLKEEYEKSCQELRETKEKMAGIEAHSELQIGQHQSELAQLHANLAR 881
Cdd:PTZ00121 1372 KKEEAKKKADAAKKKAEEKKKA-------DEAKKKAEEDKKKADELKKAAAAKKKADEAKKKAEEKKKADEAKKKAEEAK 1444

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 861483604  882 ALQQVQEKENRAQKladdlstlQEKMAATSKEVARLEALVRKAGEQQETASLELLKEPPKTRDRESEWVEEQQGQqlcsT 961
Cdd:PTZ00121 1445 KADEAKKKAEEAKK--------AEEAKKKAEEAKKADEAKKKAEEAKKADEAKKKAEEAKKKADEAKKAAEAKKK----A 1512

                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 861483604  962 QAALRAME-REAEQMGTELEKLRAALMESQGQQQEERGQQEREVARLTQERGQAEAdlalEKAAKAELEMRLQNALNEQQ 1040
Cdd:PTZ00121 1513 DEAKKAEEaKKADEAKKAEEAKKADEAKKAEEKKKADELKKAEELKKAEEKKKAEE----AKKAEEDKNMALRKAEEAKK 1588

                         490       500       510       520       530       540       550       560
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 861483604 1041 AEFANLQEALSRALSEKEGKDQELSKlcEQEAVQRMELKELLQTVEQLKAQLAKKEKEQQQSARGASGENASGMGTQSEA 1120
Cdd:PTZ00121 1589 AEEARIEEVMKLYEEEKKMKAEEAKK--AEEAKIKAEELKKAEEEKKKVEQLKKKEAEEKKKAEELKKAEEENKIKAAEE 1666

                         570       580       590       600       610       620       630       640
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 861483604 1121 VGKMEALRAKVSKLEQQCQQQQEEADSLARSLESER-AFHVERDRALETLQGQLEEKARELGYSQAasASAQRELATLRA 1199
Cdd:PTZ00121 1667 AKKAEEDKKKAEEAKKAEEDEKKAAEALKKEAEEAKkAEELKKKEAEEKKKAEELKKAEEENKIKA--EEAKKEAEEDKK 1744

                         650       660       670       680       690       700
                  ....*....|....*....|....*....|....*....|....*....|....*....|.
gi 861483604 1200 KAQDHSKAEEEwKAQVARGQQEAVRKGslissleEEVSILNRQVLEKEGESKELKRLVIAE 1260
Cdd:PTZ00121 1745 KAEEAKKDEEE-KKKIAHLKKEEEKKA-------EEIRKEKEAVIEEELDEEDEKRRMEVD 1797
Smc COG1196
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ...
 215-811 1.73e-19

Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 440809 [Multi-domain]  Cd Length: 983  Bit Score: 96.16  E-value: 1.73e-19
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 861483604  215 QMRRLKKQ---------LADERNNRDeLELELAEHRKLLTEKDAQISMMQQRIDRLALLNEKQAAspLEpRELEELRGKN 285
Cdd:COG1196   201 QLEPLERQaekaeryreLKEELKELE-AELLLLKLRELEAELEELEAELEELEAELEELEAELAE--LE-AELEELRLEL 276

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 861483604  286 ESLTFRLHETLKQCQDLKTEKGQMDRKINQLSEEngdlsfklrefasnLQQLQGALNELTEEHskatQQWVEKQAHLEKE 365
Cdd:COG1196   277 EELELELEEAQAEEYELLAELARLEQDIARLEER--------------RRELEERLEELEEEL----AELEEELEELEEE 338

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 861483604  366 LSTALQDKKCLEEKNEILQGKLSQLEERLAQLPESPRQEKGEVLGDVLQLESLKQEAATLATNNTQLQARVEMLENEQGQ 445
Cdd:COG1196   339 LEELEEELEEAEEELEEAEAELAEAEEALLEAEAELAEAEEELEELAEELLEALRAAAELAAQLEELEEAEEALLERLER 418

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 861483604  446 KEAQLLGERSHFEEEKQQLASLITNLQSSISNLSQAKEELEQASQAQGAKLNAQVASLTAELTTLSATLQQQDQELAGLK 525
Cdd:COG1196   419 LEEELEELEEALAELEEEEEEEEEALEEAAEEEAELEEEEEALLELLAELLEEAALLEAALAELLEELAEAAARLLLLLE 498

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 861483604  526 QQAQKKQAQLAQSLQQQEQASQGLRHQVEQLSGSLKQKEKQLEEAareLDASRRDHAQQLATAAKAQETSLRERDAACQQ 605
Cdd:COG1196   499 AEADYEGFLEGVKAALLLAGLRGLAGAVAVLIGVEAAYEAALEAA---LAAALQNIVVEDDEVAAAAIEYLKAAKAGRAT 575

                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 861483604  606 LEALEKEKAAKLEILQQQLQAANEAQDSAqnsvtQAQREKAELSQKVEELHALIEAAHQEQCEAQTQVAALEARLKAEQQ 685
Cdd:COG1196   576 FLPLDKIRARAALAAALARGAIGAAVDLV-----ASDLREADARYYVLGDTLLGRTLVAARLEAALRRAVTLAGRLREVT 650

                         490       500       510       520       530       540       550       560
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 861483604  686 KATEREKVAQEKAQLQEQlwSLEESLKITKGSLEEEKCRAAAALEEHQHHISEMEAESRSLAEQHKQERKELEEEKAKRR 765
Cdd:COG1196   651 LEGEGGSAGGSLTGGSRR--ELLAALLEAEAELEELAERLAEEELELEEALLAEEEEERELAEAEEERLEEELEEEALEE 728

                         570       580       590       600
                  ....*....|....*....|....*....|....*....|....*....
gi 861483604  766 GLGVQLQQLAETHQAETKALRQELAKARTSN---NMAEREVELLVKEVK 811
Cdd:COG1196   729 QLEAEREELLEELLEEEELLEEEALEELPEPpdlEELERELERLEREIE 777
Smc COG1196
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ...
 767-1349 2.52e-19

Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 440809 [Multi-domain]  Cd Length: 983  Bit Score: 95.39  E-value: 2.52e-19
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 861483604  767 LGVQLQQLAEthQAETKALRQELAKARTsnnmaEREVELLVKEVKTwrkryedsqqgetqygLQEQLTTLKEEYEKSCQE 846
Cdd:COG1196   198 LERQLEPLER--QAEKAERYRELKEELK-----ELEAELLLLKLRE----------------LEAELEELEAELEELEAE 254

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 861483604  847 LRETKEKMAGIEAHSE---LQIGQHQSELAQLHANLARALQQVQEKENRAQKLADDLSTLQEKMAATSKEVARLEALVRK 923
Cdd:COG1196   255 LEELEAELAELEAELEelrLELEELELELEEAQAEEYELLAELARLEQDIARLEERRRELEERLEELEEELAELEEELEE 334

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 861483604  924 AGEQQETASLELLKEppKTRDRESEWVEEQQGQQLCSTQAALRAMEREAEqmgtELEKLRAALMESQGQQQEERGQQERE 1003
Cdd:COG1196   335 LEEELEELEEELEEA--EEELEEAEAELAEAEEALLEAEAELAEAEEELE----ELAEELLEALRAAAELAAQLEELEEA 408

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 861483604 1004 VARLTQERGQAEADLALEKAAKAELEMRLQNALNEQQAEFANLQEALSRALSEKEGKDQELSKLCEQEAVQRMELKELLQ 1083
Cdd:COG1196   409 EEALLERLERLEEELEELEEALAELEEEEEEEEEALEEAAEEEAELEEEEEALLELLAELLEEAALLEAALAELLEELAE 488

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 861483604 1084 TVEQLKAQLAKKEKEQQQSARGASGENASGMGTQSEAVGKM------------EALRAKVSKLEQQCQQQQEEADSLARS 1151
Cdd:COG1196   489 AAARLLLLLEAEADYEGFLEGVKAALLLAGLRGLAGAVAVLigveaayeaaleAALAAALQNIVVEDDEVAAAAIEYLKA 568

                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 861483604 1152 LESERAFHVERDRALETLQGQLEEKARELGYSQAASASAQRELATLRAKAQDHSKAEEEWKAQVARGQQEAVRKGSLISS 1231
Cdd:COG1196   569 AKAGRATFLPLDKIRARAALAAALARGAIGAAVDLVASDLREADARYYVLGDTLLGRTLVAARLEAALRRAVTLAGRLRE 648

                         490       500       510       520       530       540       550       560
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 861483604 1232 LEEEVSILNRQVLEKEGESKELKRLVIAESEKSQKLEERLRLLQMETASNSARAAERSSALREEVQSLREEVEKQRAASE 1311
Cdd:COG1196   649 VTLEGEGGSAGGSLTGGSRRELLAALLEAEAELEELAERLAEEELELEEALLAEEEEERELAEAEEERLEEELEEEALEE 728

                         570       580       590
                  ....*....|....*....|....*....|....*...
gi 861483604 1312 NLRQELASQAERAEELGQELKAWQEKFFQKEQALSALQ 1349
Cdd:COG1196   729 QLEAEREELLEELLEEEELLEEEALEELPEPPDLEELE 766
SMC_prok_B TIGR02168
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...
 458-1221 2.27e-18

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274008 [Multi-domain]  Cd Length: 1179  Bit Score: 92.43  E-value: 2.27e-18
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 861483604   458 EEEKQQLASLITNLQSSISNLSQAKEELEQASQaQGAKLNAQVASLTAELTTLSATLQQQDQELAglkqqaqkkqaQLAQ 537
Cdd:TIGR02168  221 ELRELELALLVLRLEELREELEELQEELKEAEE-ELEELTAELQELEEKLEELRLEVSELEEEIE-----------ELQK 288

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 861483604   538 SLQQQEQASQGLRHQVEQLSGSLKQKEKQLEEAARELD--ASRRDHAQQLATAAKAQETSLRERdaaCQQLEALEKEKAA 615
Cdd:TIGR02168  289 ELYALANEISRLEQQKQILRERLANLERQLEELEAQLEelESKLDELAEELAELEEKLEELKEE---LESLEAELEELEA 365

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 861483604   616 KLEILQQQLQAANEAQDSAQNSVTQAQREKAELSQKVEELHALIEAAHQEQCEAQTQVAALEARLKAEQQKATER--EKV 693
Cdd:TIGR02168  366 ELEELESRLEELEEQLETLRSKVAQLELQIASLNNEIERLEARLERLEDRRERLQQEIEELLKKLEEAELKELQAelEEL 445

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 861483604   694 AQEKAQLQEQLWSLEESLKITKGSLEEEKCRAAAALEEHQHHISEMEAeSRSLAEQHKQERKELEEEKAKRRGLGVQLQQ 773
Cdd:TIGR02168  446 EEELEELQEELERLEEALEELREELEEAEQALDAAERELAQLQARLDS-LERLQENLEGFSEGVKALLKNQSGLSGILGV 524

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 861483604   774 LAETHQAETK-------ALRQELAKARTSN-NMAEREVELLVKEVKTWRKRYE-DSQQGETQYGLQEQLTTLKEEYEKSC 844
Cdd:TIGR02168  525 LSELISVDEGyeaaieaALGGRLQAVVVENlNAAKKAIAFLKQNELGRVTFLPlDSIKGTEIQGNDREILKNIEGFLGVA 604

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 861483604   845 QELRETKEK--------MAGIEAHSELQIGQHQSELAQLHANL------------------ARALQQVQEKENRAQKLAD 898
Cdd:TIGR02168  605 KDLVKFDPKlrkalsylLGGVLVVDDLDNALELAKKLRPGYRIvtldgdlvrpggvitggsAKTNSSILERRREIEELEE 684

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 861483604   899 DLSTLQEKMAATSKEVARLEALVRKAGEQQETASLELLKEPPKTRDRESEWVEEQQGQQLCSTQAALRAMER-EAEQMGT 977
Cdd:TIGR02168  685 KIEELEEKIAELEKALAELRKELEELEEELEQLRKELEELSRQISALRKDLARLEAEVEQLEERIAQLSKELtELEAEIE 764

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 861483604   978 ELEKLRAALMESQGQQQEERGQQEREVARLTQERGQAEADLAlekaakaelemRLQNALNEQQAEFANLQEALSRALSEK 1057
Cdd:TIGR02168  765 ELEERLEEAEEELAEAEAEIEELEAQIEQLKEELKALREALD-----------ELRAELTLLNEEAANLRERLESLERRI 833

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 861483604  1058 EGKDQELSKLCEQEAVQRMELKELLQTVEQLKAQLAKKEKE-QQQSARGASGENAsgmgtqseavgkMEALRAKVSKLEQ 1136
Cdd:TIGR02168  834 AATERRLEDLEEQIEELSEDIESLAAEIEELEELIEELESElEALLNERASLEEA------------LALLRSELEELSE 901

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 861483604  1137 QCQQQQEEADSLARSLESERAFHVERDRALETLQGQLEEKArelgysQAASASAQRELATLRAKAQDHSKAEEEWKAQVA 1216
Cdd:TIGR02168  902 ELRELESKRSELRRELEELREKLAQLELRLEGLEVRIDNLQ------ERLSEEYSLTLEEAEALENKIEDDEEEARRRLK 975


                   ....*
gi 861483604  1217 RGQQE 1221
Cdd:TIGR02168  976 RLENK 980
SMC_prok_B TIGR02168
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...
 904-1685 4.61e-18

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274008 [Multi-domain]  Cd Length: 1179  Bit Score: 91.66  E-value: 4.61e-18
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 861483604   904 QEKMAATSKEVARLEALVRKAGEQQETASL--ELLKEPPKTRDRESEWVEEQQGQQLCSTQAALRAMEREAEQMGTELEK 981
Cdd:TIGR02168  178 ERKLERTRENLDRLEDILNELERQLKSLERqaEKAERYKELKAELRELELALLVLRLEELREELEELQEELKEAEEELEE 257

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 861483604   982 LRAALMESQGQQQEERGQqereVARLTQERGQAEADLALEKAAKAELEMRLQnalnEQQAEFANLQEALSRALSEKEGKD 1061
Cdd:TIGR02168  258 LTAELQELEEKLEELRLE----VSELEEEIEELQKELYALANEISRLEQQKQ----ILRERLANLERQLEELEAQLEELE 329

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 861483604  1062 QELSKLCEQEAVQRMELKELLQTVEQLKAQLAKKEKEQQQSARGASGENAsgmgtqseavgKMEALRAKVSKLEQQCQQQ 1141
Cdd:TIGR02168  330 SKLDELAEELAELEEKLEELKEELESLEAELEELEAELEELESRLEELEE-----------QLETLRSKVAQLELQIASL 398

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 861483604  1142 QEEADSLARSLESERAFHVERDRALETLQGQLEEKARELgySQAASASAQRELATLRAKAQDHSKAEEEWKAQVARGQQE 1221
Cdd:TIGR02168  399 NNEIERLEARLERLEDRRERLQQEIEELLKKLEEAELKE--LQAELEELEEELEELQEELERLEEALEELREELEEAEQA 476

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 861483604  1222 AVRKGSLISSLEEEVSILNRQVLEKEGESKELKRLVIAESEKSQKLEerlRLLQ-METASNSARAAErsSALREEVQSL- 1299
Cdd:TIGR02168  477 LDAAERELAQLQARLDSLERLQENLEGFSEGVKALLKNQSGLSGILG---VLSElISVDEGYEAAIE--AALGGRLQAVv 551

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 861483604  1300 REEVEKQRAASENLRQELASQAERAEE---LGQELKAWQEKFFQKEQALSALQLEHTST----QALVSELLPAKHLCQQL 1372
Cdd:TIGR02168  552 VENLNAAKKAIAFLKQNELGRVTFLPLdsiKGTEIQGNDREILKNIEGFLGVAKDLVKFdpklRKALSYLLGGVLVVDDL 631

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 861483604  1373 Q-AEQVAAEKRHREE---LEQSKQAAGGLRTElMRAQRELG------ELVPLRQKVAEQERAAQQLRAEKASYAEQLS-- 1440
Cdd:TIGR02168  632 DnALELAKKLRPGYRivtLDGDLVRPGGVITG-GSAKTNSSilerrrEIEELEEKIEELEEKIAELEKALAELRKELEel 710

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 861483604  1441 --MLKKAHGLLAEENRGLGE-RANLGRQFLEVELDQAR----EKYIQELAAVRGDAETRLAEMRQEVQSTTHELEVMTAK 1513
Cdd:TIGR02168  711 eeELEQLRKELEELSRQISAlRKDLARLEAEVEQLEERiaqlSKELTELEAEIEELEERLEEAEEELAEAEAEIEELEAQ 790

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 861483604  1514 YEGAKVKVLEERQRFQEERqkltAQVEQLEVFQREQTKKVEELSKKLADYDQASKVQQQKLKAFQAQGGESQQEAQRLQT 1593
Cdd:TIGR02168  791 IEQLKEELKALREALDELR----AELTLLNEEAANLRERLESLERRIAATERRLEDLEEQIEELSEDIESLAAEIEELEE 866

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 861483604  1594 QLNELQVQLSQKEQAAEHYKVQMEKAKTHYDAKkqqnqelqeqLQGLEQLQKENKELRAEAERLGQELQQAGLKTKEAEQ 1673
Cdd:TIGR02168  867 LIEELESELEALLNERASLEEALALLRSELEEL----------SEELRELESKRSELRRELEELREKLAQLELRLEGLEV 936

                          810
                   ....*....|..
gi 861483604  1674 TCRHLTAQVRSL 1685
Cdd:TIGR02168  937 RIDNLQERLSEE 948
SMC_prok_B TIGR02168
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...
 326-1102 2.59e-17

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274008 [Multi-domain]  Cd Length: 1179  Bit Score: 88.96  E-value: 2.59e-17
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 861483604   326 KLREFASNLQQLQGALNELT------EEHSKATQQWVEKQAHL-EKELSTALQDKKCLEEKNEILQGKLSQLEERLAQLP 398
Cdd:TIGR02168  180 KLERTRENLDRLEDILNELErqlkslERQAEKAERYKELKAELrELELALLVLRLEELREELEELQEELKEAEEELEELT 259

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 861483604   399 ESPRQEKGEVLGDVLQLESLKQEAATLATNNTQLQARVEMLENE---QGQKEAQLLGERSHFEEEKQQLASLITNLQSSI 475
Cdd:TIGR02168  260 AELQELEEKLEELRLEVSELEEEIEELQKELYALANEISRLEQQkqiLRERLANLERQLEELEAQLEELESKLDELAEEL 339

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 861483604   476 SNLSQAKEELEQASQAQGAKLNAQVASLtAELTTLSATLQQQDQELAGLKQQAQKKQAQLAQSLQQQEQASQGLRHQVEQ 555
Cdd:TIGR02168  340 AELEEKLEELKEELESLEAELEELEAEL-EELESRLEELEEQLETLRSKVAQLELQIASLNNEIERLEARLERLEDRRER 418

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 861483604   556 LSGSLKQKEKQLEEAAREldasrrDHAQQLATAAKAQETSLRERDAACQQLEALEKEkaakLEILQQQLQAANEAQDSAQ 635
Cdd:TIGR02168  419 LQQEIEELLKKLEEAELK------ELQAELEELEEELEELQEELERLEEALEELREE----LEEAEQALDAAERELAQLQ 488

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 861483604   636 NSVTQAQREKAELSQKVEELHALIEAAHQeqceAQTQVAALEARLKAEQQKATEREKVAQEKaqLQEQLWSLEESLKITK 715
Cdd:TIGR02168  489 ARLDSLERLQENLEGFSEGVKALLKNQSG----LSGILGVLSELISVDEGYEAAIEAALGGR--LQAVVVENLNAAKKAI 562

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 861483604   716 GSLEEEKCRAAAALEEHQHHISEMEAESRSLAEQHKQER---KELEEEKAKRRGLGVQLqqLAETHQAETKALRQELAKA 792
Cdd:TIGR02168  563 AFLKQNELGRVTFLPLDSIKGTEIQGNDREILKNIEGFLgvaKDLVKFDPKLRKALSYL--LGGVLVVDDLDNALELAKK 640

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 861483604   793 RTSNNMaereveLLVKEVKTWRKRYedsqqgeTQYGLQEQLTTLKEEYEKSCQELRETKEKMagieahselqigqhQSEL 872
Cdd:TIGR02168  641 LRPGYR------IVTLDGDLVRPGG-------VITGGSAKTNSSILERRREIEELEEKIEEL--------------EEKI 693

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 861483604   873 AQLHANLARALQQVQEKENRAQKLADDLSTLQEKMAATSKEVARLEALVRKAGEQQETASLELL-----KEPPKTRDRES 947
Cdd:TIGR02168  694 AELEKALAELRKELEELEEELEQLRKELEELSRQISALRKDLARLEAEVEQLEERIAQLSKELTeleaeIEELEERLEEA 773

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 861483604   948 EWVEEQQGQQLCSTQAALRAMEREAEQMGTELEKLRAALMESQGQQQEERGQQEREVARLTQERGQAEaDLALEKAAKAE 1027
Cdd:TIGR02168  774 EEELAEAEAEIEELEAQIEQLKEELKALREALDELRAELTLLNEEAANLRERLESLERRIAATERRLE-DLEEQIEELSE 852

                          730       740       750       760       770       780       790
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 861483604  1028 LEMRLQNALNEQQAEFANLQEALSRALSEKEGKDQELSKLCEQEAVQRMELKELLQTVEQLKAQLAKKEKEQQQS 1102
Cdd:TIGR02168  853 DIESLAAEIEELEELIEELESELEALLNERASLEEALALLRSELEELSEELRELESKRSELRRELEELREKLAQL 927
PTZ00121 PTZ00121
MAEBL; Provisional
 659-1507 5.00e-17

MAEBL; Provisional


Pssm-ID: 173412 [Multi-domain]  Cd Length: 2084  Bit Score: 88.27  E-value: 5.00e-17
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 861483604  659 IEAAHQEQCEAQTQVAALEARLKAEQQKATEREKVAQEKAQLQEQLWSLEESLKITKGSLEEEKcRAAAALEEHQhhise 738
Cdd:PTZ00121 1052 IDGNHEGKAEAKAHVGQDEGLKPSYKDFDFDAKEDNRADEATEEAFGKAEEAKKTETGKAEEAR-KAEEAKKKAE----- 1125

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 861483604  739 meaESRSLAEQHKQE--RKELEEEKAKRRGLGVQLQQLAETHQAETKALRQELAKARTSNNMAEREVELLVKEVKTWRkR 816
Cdd:PTZ00121 1126 ---DARKAEEARKAEdaRKAEEARKAEDAKRVEIARKAEDARKAEEARKAEDAKKAEAARKAEEVRKAEELRKAEDAR-K 1201

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 861483604  817 YEDSQQGETQYGLQEqltTLKEEYEKSCQELRETKEkmagieahselqigqhqselAQLHANLARALQQVQEKENRAQKL 896
Cdd:PTZ00121 1202 AEAARKAEEERKAEE---ARKAEDAKKAEAVKKAEE--------------------AKKDAEEAKKAEEERNNEEIRKFE 1258

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 861483604  897 ADDLSTLQEKMAATSKEVARLEALVRKAGEQQETASLELLKEPPKTRDRESEWVEEQQGQQLcstqaalramEREAEQMG 976
Cdd:PTZ00121 1259 EARMAHFARRQAAIKAEEARKADELKKAEEKKKADEAKKAEEKKKADEAKKKAEEAKKADEA----------KKKAEEAK 1328

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 861483604  977 TELEKLRAALMESQGQQQEERGQQEREVARLTQERGQAEADlalekAAKAELEMRLQNALNEQQAEFANLQEALSRAlsE 1056
Cdd:PTZ00121 1329 KKADAAKKKAEEAKKAAEAAKAEAEAAADEAEAAEEKAEAA-----EKKKEEAKKKADAAKKKAEEKKKADEAKKKA--E 1401

                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 861483604 1057 KEGKDQELSKLCEQEAVQRMELKEllQTVEQLKAQLAKKEKEQQQSARGAsgenasgmgtqseavgKMEALRAKVSKLEQ 1136
Cdd:PTZ00121 1402 EDKKKADELKKAAAAKKKADEAKK--KAEEKKKADEAKKKAEEAKKADEA----------------KKKAEEAKKAEEAK 1463

                         490       500       510       520       530       540       550       560
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 861483604 1137 QCQQQQEEADSLARSLESERAFHVERDRALETLQGQLEEKARELGYSQAASASAQRElatlRAKAQDHSKAEEEWKAQVA 1216
Cdd:PTZ00121 1464 KKAEEAKKADEAKKKAEEAKKADEAKKKAEEAKKKADEAKKAAEAKKKADEAKKAEE----AKKADEAKKAEEAKKADEA 1539

                         570       580       590       600       610       620       630       640
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 861483604 1217 RgQQEAVRKGSLISSLEEEVSILNRQVLEKEGESKELKRLVIAESEKSQKLEERLRLLQMETASNSARAAERSSALREEV 1296
Cdd:PTZ00121 1540 K-KAEEKKKADELKKAEELKKAEEKKKAEEAKKAEEDKNMALRKAEEAKKAEEARIEEVMKLYEEEKKMKAEEAKKAEEA 1618

                         650       660       670       680       690       700       710       720
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 861483604 1297 QSLREEVEKQRAASENLRQELASQAERAEELGQELKAWQEKFFQKEQalsalqlehtstqalvsellpakhlcqqlQAEQ 1376
Cdd:PTZ00121 1619 KIKAEELKKAEEEKKKVEQLKKKEAEEKKKAEELKKAEEENKIKAAE-----------------------------EAKK 1669

                         730       740       750       760       770       780       790       800
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 861483604 1377 VAAEKRHREELEQSKQAAGGLRTELMRAQRELGELVPLRQKVAEQERAAQQLRAE---KASYAEQLSMLKKAHGLLAEEN 1453
Cdd:PTZ00121 1670 AEEDKKKAEEAKKAEEDEKKAAEALKKEAEEAKKAEELKKKEAEEKKKAEELKKAeeeNKIKAEEAKKEAEEDKKKAEEA 1749

                         810       820       830       840       850
                  ....*....|....*....|....*....|....*....|....*....|....
gi 861483604 1454 RGLGERANLGRQFLEVELDQAREKYIQELAAVRGDAETRLAEMRQEVQSTTHEL 1507
Cdd:PTZ00121 1750 KKDEEEKKKIAHLKKEEEKKAEEIRKEKEAVIEEELDEEDEKRRMEVDKKIKDI 1803
PTZ00121 PTZ00121
MAEBL; Provisional
 561-1098 9.55e-17

MAEBL; Provisional


Pssm-ID: 173412 [Multi-domain]  Cd Length: 2084  Bit Score: 87.50  E-value: 9.55e-17
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 861483604  561 KQKEKQLEEAARELDASRRDHAQQLATAAKAQET----SLRERDAACQQLEALEKEKAAKLEILQQQLQAANEAqDSAQN 636
Cdd:PTZ00121 1244 KAEEERNNEEIRKFEEARMAHFARRQAAIKAEEArkadELKKAEEKKKADEAKKAEEKKKADEAKKKAEEAKKA-DEAKK 1322

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 861483604  637 SVTQAQREKAELSQKVEELHALIEAAHQEQCEAQTQVAALEARLKAEQQKATEREKVAQEKAQLQEQLWSLEESlkitKG 716
Cdd:PTZ00121 1323 KAEEAKKKADAAKKKAEEAKKAAEAAKAEAEAAADEAEAAEEKAEAAEKKKEEAKKKADAAKKKAEEKKKADEA----KK 1398

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 861483604  717 SLEEEKCRAAAALEEHQHHISEMEAESRSLAEQHKQERKELEEEKAKRRGLGVQLQQLAETHQAETKAlrQELAKARTSN 796
Cdd:PTZ00121 1399 KAEEDKKKADELKKAAAAKKKADEAKKKAEEKKKADEAKKKAEEAKKADEAKKKAEEAKKAEEAKKKA--EEAKKADEAK 1476

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 861483604  797 NMAE--REVELLVKEVKTWRKRYEDSQQGETQYGLQEQLTtlKEEYEKSCQELRETKEKMAGIEAHSELQIgQHQSELAQ 874
Cdd:PTZ00121 1477 KKAEeaKKADEAKKKAEEAKKKADEAKKAAEAKKKADEAK--KAEEAKKADEAKKAEEAKKADEAKKAEEK-KKADELKK 1553

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 861483604  875 lhANLARALQQVQEKENRAQKLADDLSTLQEKMAATSKEVARLEALVRKAGEQQETASLELLKEPPKTRDRESEWVEEQQ 954
Cdd:PTZ00121 1554 --AEELKKAEEKKKAEEAKKAEEDKNMALRKAEEAKKAEEARIEEVMKLYEEEKKMKAEEAKKAEEAKIKAEELKKAEEE 1631

                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 861483604  955 GQQLCSTQAALRAMEREAEQMGTELEKLRAALMESQGQQQEERGQQEREVARLTQERGQAEADLALEKAAKAELEMRLQN 1034
Cdd:PTZ00121 1632 KKKVEQLKKKEAEEKKKAEELKKAEEENKIKAAEEAKKAEEDKKKAEEAKKAEEDEKKAAEALKKEAEEAKKAEELKKKE 1711

                         490       500       510       520       530       540
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 861483604 1035 ALNEQQAEFANLQEALSRALSEKEGKDQELSKLCEQEAVQRMELKELLQTV---EQLKAQLAKKEKE 1098
Cdd:PTZ00121 1712 AEEKKKAEELKKAEEENKIKAEEAKKEAEEDKKKAEEAKKDEEEKKKIAHLkkeEEKKAEEIRKEKE 1778
PTZ00121 PTZ00121
MAEBL; Provisional
 1155-1733 7.01e-16

MAEBL; Provisional


Pssm-ID: 173412 [Multi-domain]  Cd Length: 2084  Bit Score: 84.42  E-value: 7.01e-16
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 861483604 1155 ERAFHVERDRALETLQGQLEEKARELGYSQAASASAQRELAtlRAKAQDHSKAEEEWKAQVARGQQEAVRKGSLISSLEE 1234
Cdd:PTZ00121 1061 EAKAHVGQDEGLKPSYKDFDFDAKEDNRADEATEEAFGKAE--EAKKTETGKAEEARKAEEAKKKAEDARKAEEARKAED 1138

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 861483604 1235 EVSIlnrqvlEKEGESKELKRLVIA-ESEKSQKLEERLRLLQMETASNSARAAERSSAlrEEVQSLRE--EVEKQRAASE 1311
Cdd:PTZ00121 1139 ARKA------EEARKAEDAKRVEIArKAEDARKAEEARKAEDAKKAEAARKAEEVRKA--EELRKAEDarKAEAARKAEE 1210

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 861483604 1312 NLRQELASQAERAEELgQELKAWQEKFFQKEQALSALQLEHTSTQALVSELLPAKHlcQQLQAEQVAAEKRHREEL---E 1388
Cdd:PTZ00121 1211 ERKAEEARKAEDAKKA-EAVKKAEEAKKDAEEAKKAEEERNNEEIRKFEEARMAHF--ARRQAAIKAEEARKADELkkaE 1287

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 861483604 1389 QSKQAAGGLRTELMRAQRELgelvplrQKVAEQERAAQQLRAEKASYAEQLSMLKKAhgllAEENRGLGERANLGRQFLE 1468
Cdd:PTZ00121 1288 EKKKADEAKKAEEKKKADEA-------KKKAEEAKKADEAKKKAEEAKKKADAAKKK----AEEAKKAAEAAKAEAEAAA 1356

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 861483604 1469 VELDQAREKyiQELAAVRGDAETRLAEMRQEVQSTTHELEVMTAKYEGAK-----VKVLEERQRFQEERQKLTAQVEQLE 1543
Cdd:PTZ00121 1357 DEAEAAEEK--AEAAEKKKEEAKKKADAAKKKAEEKKKADEAKKKAEEDKkkadeLKKAAAAKKKADEAKKKAEEKKKAD 1434

                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 861483604 1544 VFQR--EQTKKVEELSKKLadyDQASKVQQQKLKAFQAQGGESQQEAQRLQTQLNELQVQLSQKEQAAEHYKVQMEKAKT 1621
Cdd:PTZ00121 1435 EAKKkaEEAKKADEAKKKA---EEAKKAEEAKKKAEEAKKADEAKKKAEEAKKADEAKKKAEEAKKKADEAKKAAEAKKK 1511

                         490       500       510       520       530       540       550       560
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 861483604 1622 HYDAKKQQNQELQEQLQGLEQLQKENKELRAEAERLGQELQQA-----GLKTKEAEQTCRHLTAQVRSL-EAQVAHADQQ 1695
Cdd:PTZ00121 1512 ADEAKKAEEAKKADEAKKAEEAKKADEAKKAEEKKKADELKKAeelkkAEEKKKAEEAKKAEEDKNMALrKAEEAKKAEE 1591

                         570       580       590
                  ....*....|....*....|....*....|....*...
gi 861483604 1696 LRELGKFQVASDALKSREPQAKPQLDLSIDSLDLSCEE 1733
Cdd:PTZ00121 1592 ARIEEVMKLYEEEKKMKAEEAKKAEEAKIKAEELKKAE 1629
SMC_prok_B TIGR02168
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...
 1006-1701 2.17e-15

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274008 [Multi-domain]  Cd Length: 1179  Bit Score: 82.80  E-value: 2.17e-15
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 861483604  1006 RLTQERGQAEADLALE--KAAKAELEmRLQNALNEQQAEFANLQEALSRALSEKEGKDQELSKLCEQEAVQRMELKELLQ 1083
Cdd:TIGR02168  217 ELKAELRELELALLVLrlEELREELE-ELQEELKEAEEELEELTAELQELEEKLEELRLEVSELEEEIEELQKELYALAN 295

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 861483604  1084 TVEQLKAQLakkeKEQQQSARGASGENASGMGTQSEAVGKMEALRAKVSKLEQQCQQQQEEADSLARSLESERAFHVERD 1163
Cdd:TIGR02168  296 EISRLEQQK----QILRERLANLERQLEELEAQLEELESKLDELAEELAELEEKLEELKEELESLEAELEELEAELEELE 371

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 861483604  1164 RALETLQGQLEEKARELGYSQAASASAQRELATLRAKAQDHSKAEEEWKAQVARGQQEAVRKGslISSLEEEVSILNRQV 1243
Cdd:TIGR02168  372 SRLEELEEQLETLRSKVAQLELQIASLNNEIERLEARLERLEDRRERLQQEIEELLKKLEEAE--LKELQAELEELEEEL 449

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 861483604  1244 LEKEGESKELKRLVIAESEKSQKLEERLRLLQMETASNSARAAerssalreevqSLREEVEKQRAASENLRQELASQAER 1323
Cdd:TIGR02168  450 EELQEELERLEEALEELREELEEAEQALDAAERELAQLQARLD-----------SLERLQENLEGFSEGVKALLKNQSGL 518

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 861483604  1324 AEELGQ--ELKAWQEKFfqkEQALSALQLEHTstQALVSELLPAKHLCQQLQAeQVAAEKRHREELEQSK--QAAGGLRT 1399
Cdd:TIGR02168  519 SGILGVlsELISVDEGY---EAAIEAALGGRL--QAVVVENLNAAKKAIAFLK-QNELGRVTFLPLDSIKgtEIQGNDRE 592

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 861483604  1400 ELMRAQRELGELVPLRQKVAEQERAAQQLRAEKA---SYAEQLSMLKK----------------AHGLLAeenrGLGERA 1460
Cdd:TIGR02168  593 ILKNIEGFLGVAKDLVKFDPKLRKALSYLLGGVLvvdDLDNALELAKKlrpgyrivtldgdlvrPGGVIT----GGSAKT 668

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 861483604  1461 NLGRQFLEVELDQAREKyIQELAAVRGDAETRLAEMRQEVQSTTHELEVMTAKYEGAKVKVLEER---QRFQEERQKLTA 1537
Cdd:TIGR02168  669 NSSILERRREIEELEEK-IEELEEKIAELEKALAELRKELEELEEELEQLRKELEELSRQISALRkdlARLEAEVEQLEE 747

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 861483604  1538 QVEQLEVFQREQTKKVEELSKKLADYDQASKVQQQKLKAFQAQGGESQQEAQRLQTQLNELQVQLSQKEQAAEHYKVQME 1617
Cdd:TIGR02168  748 RIAQLSKELTELEAEIEELEERLEEAEEELAEAEAEIEELEAQIEQLKEELKALREALDELRAELTLLNEEAANLRERLE 827

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 861483604  1618 KAKTHYDAKKQQNQELQEQLQG-----------LEQLQKENKELRAEAERLGQELQQAGLKTKEAEQTCRHLTAQVRSLE 1686
Cdd:TIGR02168  828 SLERRIAATERRLEDLEEQIEElsedieslaaeIEELEELIEELESELEALLNERASLEEALALLRSELEELSEELRELE 907

                          730
                   ....*....|....*
gi 861483604  1687 AQVAHADQQLRELGK 1701
Cdd:TIGR02168  908 SKRSELRRELEELRE 922
SMC_prok_B TIGR02168
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...
 829-1690 4.73e-14

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274008 [Multi-domain]  Cd Length: 1179  Bit Score: 78.17  E-value: 4.73e-14
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 861483604   829 LQEQLTTLKEEYEKScQELRETKEKMAGIEAH-SELQIGQHQSELAQLHANLARALQQVQEKENRAQKLADDLSTLQEKM 907
Cdd:TIGR02168  198 LERQLKSLERQAEKA-ERYKELKAELRELELAlLVLRLEELREELEELQEELKEAEEELEELTAELQELEEKLEELRLEV 276

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 861483604   908 AATSKEVARLEALVRKAGEQQET--ASLELLKEPPKTRDRESEWVEEQQ---GQQLCSTQAALRAMEREAEQMGTELEKL 982
Cdd:TIGR02168  277 SELEEEIEELQKELYALANEISRleQQKQILRERLANLERQLEELEAQLeelESKLDELAEELAELEEKLEELKEELESL 356

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 861483604   983 RAALMESQGQQQEergqqerevarltQERGQAEADLALEKAAKAELEMRLQnaLNEQQAEFANLQEALSRALSEKEGKDQ 1062
Cdd:TIGR02168  357 EAELEELEAELEE-------------LESRLEELEEQLETLRSKVAQLELQ--IASLNNEIERLEARLERLEDRRERLQQ 421

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 861483604  1063 ELSKLC-EQEAVQRMELKELLQTVEQLKAQLAKKEKEQQQSARGASGENASGMGTQSEAVGKMEALRAKVSKLEQQCQQQ 1141
Cdd:TIGR02168  422 EIEELLkKLEEAELKELQAELEELEEELEELQEELERLEEALEELREELEEAEQALDAAERELAQLQARLDSLERLQENL 501

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 861483604  1142 QEEADSLARSLESERAFHVERDRALETLQGQLE-EKARELGYSQAASASAQRELATLRaKAQDHSKAEEEWKA-----QV 1215
Cdd:TIGR02168  502 EGFSEGVKALLKNQSGLSGILGVLSELISVDEGyEAAIEAALGGRLQAVVVENLNAAK-KAIAFLKQNELGRVtflplDS 580

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 861483604  1216 ARGQQEAVRKGSLISSLEEEVSILNRQVLEKEGESKE----LKRLVIAES-----EKSQKLEERLRL--LQMETASNSAR 1284
Cdd:TIGR02168  581 IKGTEIQGNDREILKNIEGFLGVAKDLVKFDPKLRKAlsylLGGVLVVDDldnalELAKKLRPGYRIvtLDGDLVRPGGV 660

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 861483604  1285 AAERSSALREEVQSLREEVEkqraaseNLRQELASQAERAEELGQELKAWQEKFFQKEQALSALQLEHTSTQALVSELlp 1364
Cdd:TIGR02168  661 ITGGSAKTNSSILERRREIE-------ELEEKIEELEEKIAELEKALAELRKELEELEEELEQLRKELEELSRQISAL-- 731

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 861483604  1365 aKHLCQQLQAEQVAAEKRHREELEQSKQAAGGLRTELMRAQRELGELVPLRQKVAEQERAAQQLRAEKASYAEQLSMLKK 1444
Cdd:TIGR02168  732 -RKDLARLEAEVEQLEERIAQLSKELTELEAEIEELEERLEEAEEELAEAEAEIEELEAQIEQLKEELKALREALDELRA 810

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 861483604  1445 AHGLLAEEnrglgeranlgrqfleveldqarekyIQELAAVRGDAETRLAEMRQEVQSTTHELEVMtakyegakvkvlee 1524
Cdd:TIGR02168  811 ELTLLNEE--------------------------AANLRERLESLERRIAATERRLEDLEEQIEEL-------------- 850

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 861483604  1525 rqrfQEERQKLTAQVEQLEVFQREQTKKVEELSKKLADYDQASKVQQQKLKAFQAQGGESQQEAQRLQTQLNELQVQLSQ 1604
Cdd:TIGR02168  851 ----SEDIESLAAEIEELEELIEELESELEALLNERASLEEALALLRSELEELSEELRELESKRSELRRELEELREKLAQ 926

                          810       820       830       840       850       860       870       880
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 861483604  1605 KEQAaehykvqmekakthydakkqqnqelqeqLQGLEQLQKENKE-LRAEAERLGQELQQAGLKTKEAEQTCRHltaQVR 1683
Cdd:TIGR02168  927 LELR----------------------------LEGLEVRIDNLQErLSEEYSLTLEEAEALENKIEDDEEEARR---RLK 975


                   ....*..
gi 861483604  1684 SLEAQVA 1690
Cdd:TIGR02168  976 RLENKIK 982
SMC_prok_B TIGR02168
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...
 215-914 1.14e-13

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274008 [Multi-domain]  Cd Length: 1179  Bit Score: 77.02  E-value: 1.14e-13
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 861483604   215 QMRRLKKQLADERNNRDELELELAEHRKLLTEKDAQISMMQQRIDRL--ALLNEKQAASPLEPR------ELEELRGKNE 286
Cdd:TIGR02168  240 ELEELQEELKEAEEELEELTAELQELEEKLEELRLEVSELEEEIEELqkELYALANEISRLEQQkqilreRLANLERQLE 319

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 861483604   287 SLTFRLHETLKQCQDLKTEKGQMDRKINQLSEENGDLSFKLREFASNLQQLQGALNELTEEH---SKATQQWVEKQAHLE 363
Cdd:TIGR02168  320 ELEAQLEELESKLDELAEELAELEEKLEELKEELESLEAELEELEAELEELESRLEELEEQLetlRSKVAQLELQIASLN 399

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 861483604   364 KELSTALQDKKCLEEKNEILQGKLSQLEERL--AQLPESPRQ--EKGEVLGDVL---------------QLESLKQEAAT 424
Cdd:TIGR02168  400 NEIERLEARLERLEDRRERLQQEIEELLKKLeeAELKELQAEleELEEELEELQeelerleealeelreELEEAEQALDA 479

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 861483604   425 LATNNTQLQARVEMLENEQGQKE------AQLLGERSHFEEEKQQLASLIT---------------NLQSSI-SNLSQAK 482
Cdd:TIGR02168  480 AERELAQLQARLDSLERLQENLEgfsegvKALLKNQSGLSGILGVLSELISvdegyeaaieaalggRLQAVVvENLNAAK 559

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 861483604   483 EELE-----------------------QASQAQGAKLNAQVASLTAELTTLSATLQQ----------------------- 516
Cdd:TIGR02168  560 KAIAflkqnelgrvtflpldsikgteiQGNDREILKNIEGFLGVAKDLVKFDPKLRKalsyllggvlvvddldnalelak 639

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 861483604   517 ----------QDQELAGLKQQAQKKQAQLAQSLQQQEQASQGLRHQVEQLSGSLKQKEKQLEEAA----------RELDA 576
Cdd:TIGR02168  640 klrpgyrivtLDGDLVRPGGVITGGSAKTNSSILERRREIEELEEKIEELEEKIAELEKALAELRkeleeleeelEQLRK 719

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 861483604   577 SRRDHAQQLAtaakAQETSLRERDAACQQLEALEKEKAAKLEILQQQLQAANEAQDSAQNSVTQAQREKAELSQKVEELH 656
Cdd:TIGR02168  720 ELEELSRQIS----ALRKDLARLEAEVEQLEERIAQLSKELTELEAEIEELEERLEEAEEELAEAEAEIEELEAQIEQLK 795

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 861483604   657 ALIEAAHQEQCEAQTQVAALEARLkaeQQKATEREKVAQEKAQLQEQLWSLEESLKITKGSLEEekcrAAAALEEHQHHI 736
Cdd:TIGR02168  796 EELKALREALDELRAELTLLNEEA---ANLRERLESLERRIAATERRLEDLEEQIEELSEDIES----LAAEIEELEELI 868

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 861483604   737 SEMEAEsrslAEQHKQERKELEEEKAKRRGLGVQLQQLAETHQAETKALRQELAKARTSNNMAEREVEllvkevktwrkr 816
Cdd:TIGR02168  869 EELESE----LEALLNERASLEEALALLRSELEELSEELRELESKRSELRRELEELREKLAQLELRLE------------ 932

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 861483604   817 yedsqqgETQYGLQEQLTTLKEEYEKSCQELRETKEKMAGIEAHSELQIGQHQSELAQLHA-NLArALQQVQEKENR--- 892
Cdd:TIGR02168  933 -------GLEVRIDNLQERLSEEYSLTLEEAEALENKIEDDEEEARRRLKRLENKIKELGPvNLA-AIEEYEELKERydf 1004

                          810       820
                   ....*....|....*....|....*.
gi 861483604   893 --AQK--LADDLSTLQEKMAATSKEV 914
Cdd:TIGR02168 1005 ltAQKedLTEAKETLEEAIEEIDREA 1030
SMC_prok_B TIGR02168
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...
 1031-1703 3.99e-12

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274008 [Multi-domain]  Cd Length: 1179  Bit Score: 72.01  E-value: 3.99e-12
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 861483604  1031 RLQNALNEQQAEFANLQEALSRALSEKEGKDQELSKlceQEAVQRMELKELLQTVEQLKAQLAKKEKEQQQSARGASgen 1110
Cdd:TIGR02168  190 RLEDILNELERQLKSLERQAEKAERYKELKAELREL---ELALLVLRLEELREELEELQEELKEAEEELEELTAELQ--- 263

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 861483604  1111 asgmgtqsEAVGKMEALRAKVSKLEQQCQQQQEEADSLA---RSLESERAFHVERDRALET----LQGQLEEKARELGYS 1183
Cdd:TIGR02168  264 --------ELEEKLEELRLEVSELEEEIEELQKELYALAneiSRLEQQKQILRERLANLERqleeLEAQLEELESKLDEL 335

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 861483604  1184 QAASASAQRELATLRAKAQDHSKAEEEWKAQvargQQEAVRKgslISSLEEEVSILNRQVLEKEGESKEL-KRLVIAESE 1262
Cdd:TIGR02168  336 AEELAELEEKLEELKEELESLEAELEELEAE----LEELESR---LEELEEQLETLRSKVAQLELQIASLnNEIERLEAR 408

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 861483604  1263 KSQKLEERLRLLQMETASNSARAAERSSALREEVQSLREEVEKQRAASENLRQELASQAERAEELGQELKAWQEKFFQKE 1342
Cdd:TIGR02168  409 LERLEDRRERLQQEIEELLKKLEEAELKELQAELEELEEELEELQEELERLEEALEELREELEEAEQALDAAERELAQLQ 488

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 861483604  1343 Q---ALSALQLEHTSTQALVSELLPAK---HLCQQLQAEQVAAEKRHR----------------EELEQSKQAAGGLR-T 1399
Cdd:TIGR02168  489 ArldSLERLQENLEGFSEGVKALLKNQsglSGILGVLSELISVDEGYEaaieaalggrlqavvvENLNAAKKAIAFLKqN 568

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 861483604  1400 ELMRAQRELGELVPLRQKVAEQERAAQQLRAEKASYAEQLSMLKKAHGLLAeenrglgerANLGRQFLEVELDQAREKYI 1479
Cdd:TIGR02168  569 ELGRVTFLPLDSIKGTEIQGNDREILKNIEGFLGVAKDLVKFDPKLRKALS---------YLLGGVLVVDDLDNALELAK 639

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 861483604  1480 QELAAVR-----------------GDAETRLA--EMRQEVQSTTHELEVMTAKYEGAKvkvlEERQRFQEERQKLTAQVE 1540
Cdd:TIGR02168  640 KLRPGYRivtldgdlvrpggvitgGSAKTNSSilERRREIEELEEKIEELEEKIAELE----KALAELRKELEELEEELE 715

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 861483604  1541 QLEVFQREQTKKVEELSKKLADYDQASKVQQQKLKAFQAQGGESQQEAQRLQTQLNELQVQLSQKEQAAEHYKVQMEKAK 1620
Cdd:TIGR02168  716 QLRKELEELSRQISALRKDLARLEAEVEQLEERIAQLSKELTELEAEIEELEERLEEAEEELAEAEAEIEELEAQIEQLK 795

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 861483604  1621 thydakkqqnQELQEQLQGLEQLQKENKELRAEAERLGQELQQAGLKTKEAEQTCRHLTAQVRSLEAQVAHADQQLRELG 1700
Cdd:TIGR02168  796 ----------EELKALREALDELRAELTLLNEEAANLRERLESLERRIAATERRLEDLEEQIEELSEDIESLAAEIEELE 865


                   ...
gi 861483604  1701 KFQ 1703
Cdd:TIGR02168  866 ELI 868
SMC_prok_A TIGR02169
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of ...
 604-1425 4.43e-12

chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. It is found in a single copy and is homodimeric in prokaryotes, but six paralogs (excluded from this family) are found in eukarotes, where SMC proteins are heterodimeric. This family represents the SMC protein of archaea and a few bacteria (Aquifex, Synechocystis, etc); the SMC of other bacteria is described by TIGR02168. The N- and C-terminal domains of this protein are well conserved, but the central hinge region is skewed in composition and highly divergent. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274009 [Multi-domain]  Cd Length: 1164  Bit Score: 72.02  E-value: 4.43e-12
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 861483604   604 QQLEALEKEKAAKLEILQQQLQAANEAQDSAQNSVTQAQREKAELSQKVEELHALIEAAHQEQCEAQTQVAALEARLKAE 683
Cdd:TIGR02169  198 QQLERLRREREKAERYQALLKEKREYEGYELLKEKEALERQKEAIERQLASLEEELEKLTEEISELEKRLEEIEQLLEEL 277

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 861483604   684 QQKAteREKVAQEKAQLQEQLWSLEESLKITKGSLEEEKCRaaaaLEEHQHHISEMEAESRSLAEQHKQERKELEEEKAK 763
Cdd:TIGR02169  278 NKKI--KDLGEEEQLRVKEKIGELEAEIASLERSIAEKERE----LEDAEERLAKLEAEIDKLLAEIEELEREIEEERKR 351

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 861483604   764 RRGLGVQLQQLaethQAETKALRQELAKARTSNNMAEREVELLVKEV-KTWRKRYEdsqqgetqygLQEQLTTLKEEYEK 842
Cdd:TIGR02169  352 RDKLTEEYAEL----KEELEDLRAELEEVDKEFAETRDELKDYREKLeKLKREINE----------LKRELDRLQEELQR 417

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 861483604   843 SCQELRETKEKMAGIEAhselqigqhqsELAQLHANLARALQQVQEKENRAQKLADDLSTLQEKMAATSKEVARLEALVR 922
Cdd:TIGR02169  418 LSEELADLNAAIAGIEA-----------KINELEEEKEDKALEIKKQEWKLEQLAADLSKYEQELYDLKEEYDRVEKELS 486

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 861483604   923 KAgeQQETASLELLKEPPKTRDRESEWVEEQQGQQLCSTQAALRAMEREAEQMGTELEKlrAALMESQGQQQEERGQQER 1002
Cdd:TIGR02169  487 KL--QRELAEAEAQARASEERVRGGRAVEEVLKASIQGVHGTVAQLGSVGERYATAIEV--AAGNRLNNVVVEDDAVAKE 562

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 861483604  1003 EVARLTQERGQAEADLALEKAAKAELEMR-------LQNALN----EQQAE------------FANLQEA---------- 1049
Cdd:TIGR02169  563 AIELLKRRKAGRATFLPLNKMRDERRDLSilsedgvIGFAVDlvefDPKYEpafkyvfgdtlvVEDIEAArrlmgkyrmv 642

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 861483604  1050 -LSRALSEKEG---------KDQELSKLCEQEAVQRMelKELLQTVEQLKAQLAKKEKEQQQSARGASGEnasgmgtQSE 1119
Cdd:TIGR02169  643 tLEGELFEKSGamtggsrapRGGILFSRSEPAELQRL--RERLEGLKRELSSLQSELRRIENRLDELSQE-------LSD 713

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 861483604  1120 AVGKMEALRAKVSKLEQQCQQQQEEADSLARSLESERAFHVERDRALETLQGQLEEKARELGYSQAASASAQRELA---- 1195
Cdd:TIGR02169  714 ASRKIGEIEKEIEQLEQEEEKLKERLEELEEDLSSLEQEIENVKSELKELEARIEELEEDLHKLEEALNDLEARLShsri 793

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 861483604  1196 -TLRAKAQDHSKAEEEWKAQVARGQQEAVRKGSLISSLEEEVSILNRQVLEKEGESKELKR---LVIAESEKSQ----KL 1267
Cdd:TIGR02169  794 pEIQAELSKLEEEVSRIEARLREIEQKLNRLTLEKEYLEKEIQELQEQRIDLKEQIKSIEKeieNLNGKKEELEeeleEL 873

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 861483604  1268 EERLRLLQMEtasnsaraaerssalREEVQSLREEVEKQRAASENLRQELASQAERAEELGQELKAwqeKFFQKEQALSA 1347
Cdd:TIGR02169  874 EAALRDLESR---------------LGDLKKERDELEAQLRELERKIEELEAQIEKKRKRLSELKA---KLEALEEELSE 935

                          810       820       830       840       850       860       870       880
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 861483604  1348 LQLEHTSTQALVSELLPAKHLCQQLQAEQVAAEK------RHREELEQSKQAAGGLRTELMRAQRELGELVPLRQKVAEQ 1421
Cdd:TIGR02169  936 IEDPKGEDEEIPEEELSLEDVQAELQRVEEEIRAlepvnmLAIQEYEEVLKRLDELKEKRAKLEEERKAILERIEEYEKK 1015


                   ....
gi 861483604  1422 ERAA 1425
Cdd:TIGR02169 1016 KREV 1019
SMC_prok_A TIGR02169
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of ...
 736-1658 4.58e-12

chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. It is found in a single copy and is homodimeric in prokaryotes, but six paralogs (excluded from this family) are found in eukarotes, where SMC proteins are heterodimeric. This family represents the SMC protein of archaea and a few bacteria (Aquifex, Synechocystis, etc); the SMC of other bacteria is described by TIGR02168. The N- and C-terminal domains of this protein are well conserved, but the central hinge region is skewed in composition and highly divergent. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274009 [Multi-domain]  Cd Length: 1164  Bit Score: 71.64  E-value: 4.58e-12
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 861483604   736 ISEMEAESRSLAEQHKQERKELEEEKAKRRGLGVQLQQLAE--THQAETKALRQELAKARTSNNMaeREVELLVKEVKTW 813
Cdd:TIGR02169  165 VAEFDRKKEKALEELEEVEENIERLDLIIDEKRQQLERLRRerEKAERYQALLKEKREYEGYELL--KEKEALERQKEAI 242

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 861483604   814 RKRYEDSQqgETQYGLQEQLTTLKEEYEKSCQELRETKEKmagIEAHSELQIGQHQSELAQLHANLARALQQVQEKENRA 893
Cdd:TIGR02169  243 ERQLASLE--EELEKLTEEISELEKRLEEIEQLLEELNKK---IKDLGEEEQLRVKEKIGELEAEIASLERSIAEKEREL 317

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 861483604   894 QKLADDLSTLQEKMaatSKEVARLEALVRKAGEQQetasleLLKEPPKTRDRESEWVEEQQGQQLCSTQAALRAMEREAE 973
Cdd:TIGR02169  318 EDAEERLAKLEAEI---DKLLAEIEELEREIEEER------KRRDKLTEEYAELKEELEDLRAELEEVDKEFAETRDELK 388

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 861483604   974 QMGTELEKLRAALMESQGQQQEERGQQErevaRLTQERGQAEADLALEKAAKAELEMRLQnalnEQQAEFANLQEALSRA 1053
Cdd:TIGR02169  389 DYREKLEKLKREINELKRELDRLQEELQ----RLSEELADLNAAIAGIEAKINELEEEKE----DKALEIKKQEWKLEQL 460

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 861483604  1054 LSEKEGKDQELSKLceqeavqRMELKELLQTVEQLKAQLAKKEKEQQQSARGASGENASgmgtqseavgkMEALRAKVSK 1133
Cdd:TIGR02169  461 AADLSKYEQELYDL-------KEEYDRVEKELSKLQRELAEAEAQARASEERVRGGRAV-----------EEVLKASIQG 522

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 861483604  1134 LEQQCQQQQEEADSLARSLESE-----RAFHVERD----RALETLqgqleeKARELGYSQ----AASASAQRELATLRAK 1200
Cdd:TIGR02169  523 VHGTVAQLGSVGERYATAIEVAagnrlNNVVVEDDavakEAIELL------KRRKAGRATflplNKMRDERRDLSILSED 596

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 861483604  1201 -----AQDHSKAEEEWKAQVArgqqEAVRKGSLISSLEEEVSILNRQvlekegeskelkRLVIAESEKSQKLEerlrllQ 1275
Cdd:TIGR02169  597 gvigfAVDLVEFDPKYEPAFK----YVFGDTLVVEDIEAARRLMGKY------------RMVTLEGELFEKSG------A 654

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 861483604  1276 METASNSARAAE-RSSALREEVQSLREEVEKQRAASENLRQELASQAERAEELGQELKAWQEKffqkeqaLSALQLEhts 1354
Cdd:TIGR02169  655 MTGGSRAPRGGIlFSRSEPAELQRLRERLEGLKRELSSLQSELRRIENRLDELSQELSDASRK-------IGEIEKE--- 724

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 861483604  1355 tqalvsellpakhlcqqlqaeqvaaekrhREELEQSKQAAGGLRTELMRAQRELgelvplRQKVAEQERAAQQLRAEKAS 1434
Cdd:TIGR02169  725 -----------------------------IEQLEQEEEKLKERLEELEEDLSSL------EQEIENVKSELKELEARIEE 769

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 861483604  1435 YAEQLSMLKKAhgllaeenrglgeRANLGRQFLEVELDQAREKYiQELAAVRGDAETRLAEMRQEVQSTTHELEVMtaky 1514
Cdd:TIGR02169  770 LEEDLHKLEEA-------------LNDLEARLSHSRIPEIQAEL-SKLEEEVSRIEARLREIEQKLNRLTLEKEYL---- 831

                          810       820       830       840       850       860       870       880
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 861483604  1515 egakvkvleerqrfQEERQKLTAQVEQLEVFQREQTKKVEELSKKLADYDQASKVQQQKLKAFQAQGGESQQEAQRLQTQ 1594
Cdd:TIGR02169  832 --------------EKEIQELQEQRIDLKEQIKSIEKEIENLNGKKEELEEELEELEAALRDLESRLGDLKKERDELEAQ 897

                          890       900       910       920       930       940       950
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 861483604  1595 LNELQVQLSQKEQAAEHYKVQMEKAK----------THYDAKKQQNQELQEQLQGLEQLQKENKELRAEAERLG 1658
Cdd:TIGR02169  898 LRELERKIEELEAQIEKKRKRLSELKaklealeeelSEIEDPKGEDEEIPEEELSLEDVQAELQRVEEEIRALE 971
SMC_prok_A TIGR02169
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of ...
 652-1559 8.14e-12

chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. It is found in a single copy and is homodimeric in prokaryotes, but six paralogs (excluded from this family) are found in eukarotes, where SMC proteins are heterodimeric. This family represents the SMC protein of archaea and a few bacteria (Aquifex, Synechocystis, etc); the SMC of other bacteria is described by TIGR02168. The N- and C-terminal domains of this protein are well conserved, but the central hinge region is skewed in composition and highly divergent. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274009 [Multi-domain]  Cd Length: 1164  Bit Score: 70.87  E-value: 8.14e-12
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 861483604   652 VEELHALIEAAHQEQCEAQTQVAALEARLKaeqQKATEREKVAQEKAQLQEQLWSLEESLKITKGSLEEEKCRAAAALEE 731
Cdd:TIGR02169  165 VAEFDRKKEKALEELEEVEENIERLDLIID---EKRQQLERLRREREKAERYQALLKEKREYEGYELLKEKEALERQKEA 241

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 861483604   732 HQHHISEMEAESRSLAEQHKQERKELEEEKAKRRGLGVQLQQLAETHQAETKALRQELakartsnnmaEREVELLVKEVK 811
Cdd:TIGR02169  242 IERQLASLEEELEKLTEEISELEKRLEEIEQLLEELNKKIKDLGEEEQLRVKEKIGEL----------EAEIASLERSIA 311

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 861483604   812 TWRKRYEDSQqgETQYGLQEQLTTLKEEYEKSCQELRETKEKMAGIEAhselqigqhqsELAQLHANLARALQQVQEKEN 891
Cdd:TIGR02169  312 EKERELEDAE--ERLAKLEAEIDKLLAEIEELEREIEEERKRRDKLTE-----------EYAELKEELEDLRAELEEVDK 378

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 861483604   892 RAQKLADDLSTLQEKMAATSKEVARLEALVRKAGEQQETASLELlkeppktrdresewveEQQGQQLCSTQAALRAMERE 971
Cdd:TIGR02169  379 EFAETRDELKDYREKLEKLKREINELKRELDRLQEELQRLSEEL----------------ADLNAAIAGIEAKINELEEE 442

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 861483604   972 AEQMGTELEKLRAALMesqgqqqeergqqerevaRLTQERGQAEADLALEKAAKAELEMRLqnalneqqaefanlqEALS 1051
Cdd:TIGR02169  443 KEDKALEIKKQEWKLE------------------QLAADLSKYEQELYDLKEEYDRVEKEL---------------SKLQ 489

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 861483604  1052 RALSEKEGKDQELSKLCEQEAVQRMELKELLQTVEQLKAQLAKKEKEQQQSARGASGENASGMGTQSEAVGK--MEALRA 1129
Cdd:TIGR02169  490 RELAEAEAQARASEERVRGGRAVEEVLKASIQGVHGTVAQLGSVGERYATAIEVAAGNRLNNVVVEDDAVAKeaIELLKR 569

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 861483604  1130 K---------VSKLEQQCQQQQEEADS----------------------------LARSLESERAfHVERDRaLETLQGQ 1172
Cdd:TIGR02169  570 RkagratflpLNKMRDERRDLSILSEDgvigfavdlvefdpkyepafkyvfgdtlVVEDIEAARR-LMGKYR-MVTLEGE 647

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 861483604  1173 LEEKARELGYSQAASASAQRELATLRAKAQDHSKAEEEWKAQVARGQQEAVRKGSLISSLEEEVSILNRQVLEKEGESKE 1252
Cdd:TIGR02169  648 LFEKSGAMTGGSRAPRGGILFSRSEPAELQRLRERLEGLKRELSSLQSELRRIENRLDELSQELSDASRKIGEIEKEIEQ 727

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 861483604  1253 LKRLVIAESEKSQKLEERLRLLQMETASNSARAAErssaLREEVQSLREEVEKQRAASENLRQELASQ-----AERAEEL 1327
Cdd:TIGR02169  728 LEQEEEKLKERLEELEEDLSSLEQEIENVKSELKE----LEARIEELEEDLHKLEEALNDLEARLSHSripeiQAELSKL 803

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 861483604  1328 GQELKAWQEKFFQKEQALSALQLEHTSTQALVSELlpakhlcQQLQAEQVAAEKRHREELEQSKQAAGGLRTELMRAQRE 1407
Cdd:TIGR02169  804 EEEVSRIEARLREIEQKLNRLTLEKEYLEKEIQEL-------QEQRIDLKEQIKSIEKEIENLNGKKEELEEELEELEAA 876

                          810       820       830       840       850       860       870       880
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 861483604  1408 LGELVPLRQKVAEQ-ERAAQQLRAEKASYAEQLSMLKKAHGLLAEENRGLGeraNLGRQFLEVELDQAREKYIQELAAVR 1486
Cdd:TIGR02169  877 LRDLESRLGDLKKErDELEAQLRELERKIEELEAQIEKKRKRLSELKAKLE---ALEEELSEIEDPKGEDEEIPEEELSL 953

                          890       900       910       920       930       940       950
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 861483604  1487 GDaetrLAEMRQEVQSTTHELEVMTAKYEGAKVKVLEERQRFQEERQKLTAQVEQLevfqREQTKKVEELSKK 1559
Cdd:TIGR02169  954 ED----VQAELQRVEEEIRALEPVNMLAIQEYEEVLKRLDELKEKRAKLEEERKAI----LERIEEYEKKKRE 1018
COG4913 COG4913
Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];
564-1067 8.68e-12

Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];


Pssm-ID: 443941 [Multi-domain]  Cd Length: 1089  Bit Score: 70.71  E-value: 8.68e-12
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 861483604  564 EKQLEEAARELDASRRDH--AQQLATAAKAQETSLRERDAACQQLEALEKEK--------AAKLEILQQQLQAANEAQDS 633
Cdd:COG4913   220 EPDTFEAADALVEHFDDLerAHEALEDAREQIELLEPIRELAERYAAARERLaeleylraALRLWFAQRRLELLEAELEE 299

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 861483604  634 AQNSVTQAQREKAELSQKVEELHALIEAAHQEQCEAQTQ-VAALEARLKAEQQkatEREKVAQEKAQLQEQLWSLEESLK 712
Cdd:COG4913   300 LRAELARLEAELERLEARLDALREELDELEAQIRGNGGDrLEQLEREIERLER---ELEERERRRARLEALLAALGLPLP 376

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 861483604  713 ITKGSLEEEKCRAAAALEEHQHHISEMEAESRSLAEQHKQERKELEEEKAKRRglgvQLQQLAETHQAETKALRQELAKA 792
Cdd:COG4913   377 ASAEEFAALRAEAAALLEALEEELEALEEALAEAEAALRDLRRELRELEAEIA----SLERRKSNIPARLLALRDALAEA 452

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 861483604  793 RtsnNMAEREV----ELLvkEVKT----WR------------------KRYEDSQQGETQYGLQEQLTTLKEeyekscqE 846
Cdd:COG4913   453 L---GLDEAELpfvgELI--EVRPeeerWRgaiervlggfaltllvppEHYAAALRWVNRLHLRGRLVYERV-------R 520

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 861483604  847 LRETKEKMAGIEAHS---ELQIGQH------QSELA-------------------------QLHANLAR----------- 881
Cdd:COG4913   521 TGLPDPERPRLDPDSlagKLDFKPHpfrawlEAELGrrfdyvcvdspeelrrhpraitragQVKGNGTRhekddrrrirs 600

                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 861483604  882 -------ALQQVQEKENRAQKLADDLSTLQEKMAATSKEVARLEALVRKAGEQQETASLELlkEPPKTRDRESEWveEQQ 954
Cdd:COG4913   601 ryvlgfdNRAKLAALEAELAELEEELAEAEERLEALEAELDALQERREALQRLAEYSWDEI--DVASAEREIAEL--EAE 676

                         490       500       510       520       530       540       550       560
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 861483604  955 GQQLCSTQAALRAMEREAEQMGTELEKLRAALMESQGQQQEERGQQEREVARLTQERGQAEADLALEKAAK-AELEMRLQ 1033
Cdd:COG4913   677 LERLDASSDDLAALEEQLEELEAELEELEEELDELKGEIGRLEKELEQAEEELDELQDRLEAAEDLARLELrALLEERFA 756

                         570       580       590
                  ....*....|....*....|....*....|....*.
gi 861483604 1034 NALNEQQAE--FANLQEALSRALSEKEGKDQELSKL 1067
Cdd:COG4913   757 AALGDAVERelRENLEERIDALRARLNRAEEELERA 792
SMC_N pfam02463
RecF/RecN/SMC N terminal domain; This domain is found at the N terminus of SMC proteins. The ...
 350-1101 1.66e-11

RecF/RecN/SMC N terminal domain; This domain is found at the N terminus of SMC proteins. The SMC (structural maintenance of chromosomes) superfamily proteins have ATP-binding domains at the N- and C-termini, and two extended coiled-coil domains separated by a hinge in the middle. The eukaryotic SMC proteins form two kind of heterodimers: the SMC1/SMC3 and the SMC2/SMC4 types. These heterodimers constitute an essential part of higher order complexes, which are involved in chromatin and DNA dynamics. This family also includes the RecF and RecN proteins that are involved in DNA metabolism and recombination.


Pssm-ID: 426784 [Multi-domain]  Cd Length: 1161  Bit Score: 70.00  E-value: 1.66e-11
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 861483604   350 KATQQWVEKQAHLEKELSTALQDKKcLEEKNEilqgKLSQLEERLAQLPESPRQEKgevlgdvLQLESLKQEAATLATNN 429
Cdd:pfam02463  146 IIAMMKPERRLEIEEEAAGSRLKRK-KKEALK----KLIEETENLAELIIDLEELK-------LQELKLKEQAKKALEYY 213

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 861483604   430 TQLQARVEMLENEQGQKEAQLLGERSHFEEEKQQLASLITNLQSSISNLSQAKEELEQASQAQGAKLNAQVASLTAELTT 509
Cdd:pfam02463  214 QLKEKLELEEEYLLYLDYLKLNEERIDLLQELLRDEQEEIESSKQEIEKEEEKLAQVLKENKEEEKEKKLQEEELKLLAK 293

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 861483604   510 LSATLQQQDQELAGLKQQAQKKQAQLAQSLQQQEQASQGLRHQVEQLSGSLKQKEKQLEEAARELDASRrdhaQQLATAA 589
Cdd:pfam02463  294 EEEELKSELLKLERRKVDDEEKLKESEKEKKKAEKELKKEKEEIEELEKELKELEIKREAEEEEEEELE----KLQEKLE 369

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 861483604   590 KAQETSLRERDAACQQLEALEKEKAAKLEILQQQLQAANEAQDSAQNSVTQAQREKAELSQKVEELHALIEAAHQEQCEA 669
Cdd:pfam02463  370 QLEEELLAKKKLESERLSSAAKLKEEELELKSEEEKEAQLLLELARQLEDLLKEEKKEELEILEEEEESIELKQGKLTEE 449

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 861483604   670 QTQVAALEARLKAEQQKAtEREKVAQEKAQLQEQLWSLEESLKITKGSLEEEKCRAAAALEEHQHHISEMEAESRSLAEQ 749
Cdd:pfam02463  450 KEELEKQELKLLKDELEL-KKSEDLLKETQLVKLQEQLELLLSRQKLEERSQKESKARSGLKVLLALIKDGVGGRIISAH 528

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 861483604   750 HKQERKELEEEKAKRRGLGVQLQQLAETHQAETKA--LRQELAKARTSNNMAEREVELLVKEVKTWRKRYEDSQQGETQY 827
Cdd:pfam02463  529 GRLGDLGVAVENYKVAISTAVIVEVSATADEVEERqkLVRALTELPLGARKLRLLIPKLKLPLKSIAVLEIDPILNLAQL 608

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 861483604   828 GLQEQLTTLKEEYEKSCQELRETKEKMAGIEAHSELQIG-QHQSELAQLHANLARALQQVQEKEnRAQKLADDLSTLQEK 906
Cdd:pfam02463  609 DKATLEADEDDKRAKVVEGILKDTELTKLKESAKAKESGlRKGVSLEEGLAEKSEVKASLSELT-KELLEIQELQEKAES 687

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 861483604   907 MAATSKEVARLEALVRKAGEQQETASLELLKEPPKTRDRESEWVEEQQGQQLCSTQAALRAMEREAEQMGTELEKLRAAL 986
Cdd:pfam02463  688 ELAKEEILRRQLEIKKKEQREKEELKKLKLEAEELLADRVQEAQDKINEELKLLKQKIDEEEEEEEKSRLKKEEKEEEKS 767

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 861483604   987 MESQGQQQEERGQQEREVARLTQERGQAEADLALEKAAKAElEMRLQNALNEQQAEFANLQEALSRALSEKEGKDQELSK 1066
Cdd:pfam02463  768 ELSLKEKELAEEREKTEKLKVEEEKEEKLKAQEEELRALEE-ELKEEAELLEEEQLLIEQEEKIKEEELEELALELKEEQ 846

                          730       740       750
                   ....*....|....*....|....*....|....*
gi 861483604  1067 LCEQEAVQRMELKELLQTVEQLKAQLAKKEKEQQQ 1101
Cdd:pfam02463  847 KLEKLAEEELERLEEEITKEELLQELLLKEEELEE 881
SMC_prok_A TIGR02169
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of ...
 549-1302 2.84e-11

chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. It is found in a single copy and is homodimeric in prokaryotes, but six paralogs (excluded from this family) are found in eukarotes, where SMC proteins are heterodimeric. This family represents the SMC protein of archaea and a few bacteria (Aquifex, Synechocystis, etc); the SMC of other bacteria is described by TIGR02168. The N- and C-terminal domains of this protein are well conserved, but the central hinge region is skewed in composition and highly divergent. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274009 [Multi-domain]  Cd Length: 1164  Bit Score: 69.33  E-value: 2.84e-11
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 861483604   549 LRHQVEQLSGSLKQKEKQLEEAARELDASRRDHAQQLATAAKAQETSLRERDAACQQLEALEK---EKAAKLEILQQQLQ 625
Cdd:TIGR02169  196 KRQQLERLRREREKAERYQALLKEKREYEGYELLKEKEALERQKEAIERQLASLEEELEKLTEeisELEKRLEEIEQLLE 275

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 861483604   626 AANEA-QDSAQNSVTQAQREKAELSQKVEELHALIEAAHQEQCEAQTQVAALEArlkaeqqkatEREKVAQEKAQLQEQL 704
Cdd:TIGR02169  276 ELNKKiKDLGEEEQLRVKEKIGELEAEIASLERSIAEKERELEDAEERLAKLEA----------EIDKLLAEIEELEREI 345

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 861483604   705 wsleESLKITKGSLEEEKCRAAAALEEHQHHISEMEAESRSLAEQHKQERKELEEEKAKRRGLGVQLQQLAETHQ---AE 781
Cdd:TIGR02169  346 ----EEERKRRDKLTEEYAELKEELEDLRAELEEVDKEFAETRDELKDYREKLEKLKREINELKRELDRLQEELQrlsEE 421

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 861483604   782 TKALRQELAKARTSNNMAEREVELLVKEVKTwrkryedsqqgetqygLQEQLTTLKEEYEKSCQELRETKEKMAGIEAhs 861
Cdd:TIGR02169  422 LADLNAAIAGIEAKINELEEEKEDKALEIKK----------------QEWKLEQLAADLSKYEQELYDLKEEYDRVEK-- 483

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 861483604   862 elQIGQHQSELAQLHANlARALQQVQEKENRAQKLAD-----------DLSTLQEKMAaTSKEVA---RLEALVRKAGEQ 927
Cdd:TIGR02169  484 --ELSKLQRELAEAEAQ-ARASEERVRGGRAVEEVLKasiqgvhgtvaQLGSVGERYA-TAIEVAagnRLNNVVVEDDAV 559

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 861483604   928 QETAsLELLKEPP----------KTRDRESE---------------WVEEQQGQQLCSTQA-----ALRAMEREAEQMG- 976
Cdd:TIGR02169  560 AKEA-IELLKRRKagratflplnKMRDERRDlsilsedgvigfavdLVEFDPKYEPAFKYVfgdtlVVEDIEAARRLMGk 638

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 861483604   977 ------------------------TELEKLRAALMESQGQQQEERGQQEREVARLTQERGQAE--ADLALEKAAKAELEM 1030
Cdd:TIGR02169  639 yrmvtlegelfeksgamtggsrapRGGILFSRSEPAELQRLRERLEGLKRELSSLQSELRRIEnrLDELSQELSDASRKI 718

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 861483604  1031 RL----QNALNEQQAEFANLQEALSRALSEKEgkdQELSKLCEQEAVQRMELKELLQTVEQLKAQLAKKEKEQQQSARGA 1106
Cdd:TIGR02169  719 GEiekeIEQLEQEEEKLKERLEELEEDLSSLE---QEIENVKSELKELEARIEELEEDLHKLEEALNDLEARLSHSRIPE 795

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 861483604  1107 SGENASGMGTQ-SEAVGKMEALRAKVSKLEQQCQQQQEEADSLARSLESERAFHVERDRALETLQGQLEEKARELGYSQA 1185
Cdd:TIGR02169  796 IQAELSKLEEEvSRIEARLREIEQKLNRLTLEKEYLEKEIQELQEQRIDLKEQIKSIEKEIENLNGKKEELEEELEELEA 875

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 861483604  1186 ASASAQRELATLRAKAQDHSKAEEEWKAQVARGQQEAVRKGSLISSLEEEVSILNRQVLEKEGESKELKRLVIAE----- 1260
Cdd:TIGR02169  876 ALRDLESRLGDLKKERDELEAQLRELERKIEELEAQIEKKRKRLSELKAKLEALEEELSEIEDPKGEDEEIPEEElsled 955

                          810       820       830       840
                   ....*....|....*....|....*....|....*....|....*.
gi 861483604  1261 -SEKSQKLEERLRLLQ---METASNSARAAERSSALREEVQSLREE 1302
Cdd:TIGR02169  956 vQAELQRVEEEIRALEpvnMLAIQEYEEVLKRLDELKEKRAKLEEE 1001
CALCOCO1 pfam07888
Calcium binding and coiled-coil domain (CALCOCO1) like; Proteins found in this family are ...
 635-982 5.78e-11

Calcium binding and coiled-coil domain (CALCOCO1) like; Proteins found in this family are similar to the coiled-coil transcriptional coactivator protein coexpressed by Mus musculus (CoCoA/CALCOCO1). This protein binds to a highly conserved N-terminal domain of p160 coactivators, such as GRIP1, and thus enhances transcriptional activation by a number of nuclear receptors. CALCOCO1 has a central coiled-coil region with three leucine zipper motifs, which is required for its interaction with GRIP1 and may regulate the autonomous transcriptional activation activity of the C-terminal region.


Pssm-ID: 462303 [Multi-domain]  Cd Length: 488  Bit Score: 67.23  E-value: 5.78e-11
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 861483604   635 QNSVTQAQREKAELSQKVEelhALIEAAHQEQCEAQTQVAALEARLKAEQQKATEREKVAQEKAQLQEQLWSLEESLKIT 714
Cdd:pfam07888   33 QNRLEECLQERAELLQAQE---AANRQREKEKERYKRDREQWERQRRELESRVAELKEELRQSREKHEELEEKYKELSAS 109

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 861483604   715 KGSLEEEKCRAAAALEEHQHHISEMEAESRSLAEQHKQERKELEEEKAKRRGLGVQ----------LQQLAETHQAETKA 784
Cdd:pfam07888  110 SEELSEEKDALLAQRAAHEARIRELEEDIKTLTQRVLERETELERMKERAKKAGAQrkeeeaerkqLQAKLQQTEEELRS 189

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 861483604   785 LRQELAKARTSNNMAEREVELLVKEVKTWRKRYEDSQQGETQY-GLQEQLTTLKEEYEKSCQE---LRETKEKMAGIEAH 860
Cdd:pfam07888  190 LSKEFQELRNSLAQRDTQVLQLQDTITTLTQKLTTAHRKEAENeALLEELRSLQERLNASERKvegLGEELSSMAAQRDR 269

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 861483604   861 SELQIGQHQSELAQLHANLARALQQVQEKENRAQK----LADDLSTLQEKMAATSKEVARLEALVRKAGEQQETASLELL 936
Cdd:pfam07888  270 TQAELHQARLQAAQLTLQLADASLALREGRARWAQeretLQQSAEADKDRIEKLSAELQRLEERLQEERMEREKLEVELG 349

                          330       340       350       360
                   ....*....|....*....|....*....|....*....|....*.
gi 861483604   937 KEPPKTRDRESEWVEEQQGQqlcstQAALRAMEREAEQMGTELEKL 982
Cdd:pfam07888  350 REKDCNRVQLSESRRELQEL-----KASLRVAQKEKEQLQAEKQEL 390
PTZ00121 PTZ00121
MAEBL; Provisional
 274-953 6.14e-11

MAEBL; Provisional


Pssm-ID: 173412 [Multi-domain]  Cd Length: 2084  Bit Score: 68.24  E-value: 6.14e-11
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 861483604  274 EPRELEELRGKNESltfRLHETLKQCQDLK--TEKGQMDRKINQLSEENGDLSFKLREFASNLQQLQGALNELTEEHSKA 351
Cdd:PTZ00121 1210 EERKAEEARKAEDA---KKAEAVKKAEEAKkdAEEAKKAEEERNNEEIRKFEEARMAHFARRQAAIKAEEARKADELKKA 1286

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 861483604  352 TQQWVEKQAHLEKELSTALQDKKCLEEKNEILQGKlSQLEERLAQLPESprQEKGEVLGDVLQLESLKQEAATLATNNTQ 431
Cdd:PTZ00121 1287 EEKKKADEAKKAEEKKKADEAKKKAEEAKKADEAK-KKAEEAKKKADAA--KKKAEEAKKAAEAAKAEAEAAADEAEAAE 1363

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 861483604  432 LQARVEMLENEQGQKEAQLLGERShfeEEKQQLASLITNLQssisnlsQAKEELEQASQAQGAKLNAQVASLTAELTTLS 511
Cdd:PTZ00121 1364 EKAEAAEKKKEEAKKKADAAKKKA---EEKKKADEAKKKAE-------EDKKKADELKKAAAAKKKADEAKKKAEEKKKA 1433

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 861483604  512 ATLQQQDQELAGLKQQAQKKQAqlaqslqqqeqasqglRHQVEQLSGSLKQKEKQLEEAARELDASRRDHAQQLATAAKA 591
Cdd:PTZ00121 1434 DEAKKKAEEAKKADEAKKKAEE----------------AKKAEEAKKKAEEAKKADEAKKKAEEAKKADEAKKKAEEAKK 1497

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 861483604  592 QETSLRERDAACQQLEALEKEKAAKLeilQQQLQAANEAQdSAQNSVTQAQREKAELSQKVEELHALIEAAHQEQ----- 666
Cdd:PTZ00121 1498 KADEAKKAAEAKKKADEAKKAEEAKK---ADEAKKAEEAK-KADEAKKAEEKKKADELKKAEELKKAEEKKKAEEakkae 1573

                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 861483604  667 --------------------CEAQTQVAALEARLKAEQQKATEREKVAQEKAQLQEQLWSLEESLKitkgSLEEEKCRAA 726
Cdd:PTZ00121 1574 edknmalrkaeeakkaeearIEEVMKLYEEEKKMKAEEAKKAEEAKIKAEELKKAEEEKKKVEQLK----KKEAEEKKKA 1649

                         490       500       510       520       530       540       550       560
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 861483604  727 AALEEHQHHISEMEAESRSLAEQHKQERKELEEEKAKRRGLGVQLQQLAETHQAETKALRQELAKARTSNNMAEREVELL 806
Cdd:PTZ00121 1650 EELKKAEEENKIKAAEEAKKAEEDKKKAEEAKKAEEDEKKAAEALKKEAEEAKKAEELKKKEAEEKKKAEELKKAEEENK 1729

                         570       580       590       600       610       620       630       640
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 861483604  807 VKEVKTWRKRYEDSQQGE---TQYGLQEQLTTLKEEYEKSCQELRetKEKMAGIEAHSELQIGQHQSELAQLHANLARAL 883
Cdd:PTZ00121 1730 IKAEEAKKEAEEDKKKAEeakKDEEEKKKIAHLKKEEEKKAEEIR--KEKEAVIEEELDEEDEKRRMEVDKKIKDIFDNF 1807

                         650       660       670       680       690       700       710
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 861483604  884 QQVQEKENRAQKLADDlstLQEKMAATSKEVARLEALVRKAGEQQETASLELLKEPPKTRDRESEWVEEQ 953
Cdd:PTZ00121 1808 ANIIEGGKEGNLVIND---SKEMEDSAIKEVADSKNMQLEEADAFEKHKFNKNNENGEDGNKEADFNKEK 1874
Smc COG1196
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ...
 1373-1709 1.17e-10

Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 440809 [Multi-domain]  Cd Length: 983  Bit Score: 67.27  E-value: 1.17e-10
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 861483604 1373 QAEQVAAEKRHREELEQSKQAAGGLRTELMRAQRELgelvpLRQKVAEQERAAQQLRAEKASYAEQLSMLKKAHGLLAEE 1452
Cdd:COG1196   208 QAEKAERYRELKEELKELEAELLLLKLRELEAELEE-----LEAELEELEAELEELEAELAELEAELEELRLELEELELE 282

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 861483604 1453 NRGLGERANLgrqfLEVELDQAREKyIQELAAVRGDAETRLAEMRQEVQSTTHELEVMTAKYEGAKVKVLEERQRFQEER 1532
Cdd:COG1196   283 LEEAQAEEYE----LLAELARLEQD-IARLEERRRELEERLEELEEELAELEEELEELEEELEELEEELEEAEEELEEAE 357

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 861483604 1533 QKLTAQVEQLEVFQREQTKKVEELSKKLADYDQAskvqQQKLKAFQAQGGESQQEAQRLQTQLNELQVQLSQKEQAAEHY 1612
Cdd:COG1196   358 AELAEAEEALLEAEAELAEAEEELEELAEELLEA----LRAAAELAAQLEELEEAEEALLERLERLEEELEELEEALAEL 433

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 861483604 1613 KVQMEKAKTHYDAKKQQNQELQEQLQGLEQLQKENKELRAEAERLGQELQQAGLKTKEAEQTCRHLTAQVRSLEAQVAHA 1692
Cdd:COG1196   434 EEEEEEEEEALEEAAEEEAELEEEEEALLELLAELLEEAALLEAALAELLEELAEAAARLLLLLEAEADYEGFLEGVKAA 513

                         330
                  ....*....|....*..
gi 861483604 1693 DQQLRELGKFQVASDAL 1709
Cdd:COG1196   514 LLLAGLRGLAGAVAVLI 530
SMC_prok_A TIGR02169
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of ...
 215-924 1.56e-10

chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. It is found in a single copy and is homodimeric in prokaryotes, but six paralogs (excluded from this family) are found in eukarotes, where SMC proteins are heterodimeric. This family represents the SMC protein of archaea and a few bacteria (Aquifex, Synechocystis, etc); the SMC of other bacteria is described by TIGR02168. The N- and C-terminal domains of this protein are well conserved, but the central hinge region is skewed in composition and highly divergent. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274009 [Multi-domain]  Cd Length: 1164  Bit Score: 66.63  E-value: 1.56e-10
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 861483604   215 QMRRLKKQLADERNNRDELELELAEHRKLLTEKDAQISMMQQRIDRL-------------------ALLNEKQAASPLEP 275
Cdd:TIGR02169  238 QKEAIERQLASLEEELEKLTEEISELEKRLEEIEQLLEELNKKIKDLgeeeqlrvkekigeleaeiASLERSIAEKEREL 317

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 861483604   276 RELEELRGKNESltfRLHETLKQCQDLKTEKGQMDRKINQLSEENGDLSFKLREFASNLQQLQGALNELTEEHSKATQ-- 353
Cdd:TIGR02169  318 EDAEERLAKLEA---EIDKLLAEIEELEREIEEERKRRDKLTEEYAELKEELEDLRAELEEVDKEFAETRDELKDYREkl 394

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 861483604   354 -QWVEKQAHLEKELSTALQDKKCLEEKNEILQGKLSQLEERLAQLPESPRQEKGEVLGDVLQLESLKQEAATLATNNTQL 432
Cdd:TIGR02169  395 eKLKREINELKRELDRLQEELQRLSEELADLNAAIAGIEAKINELEEEKEDKALEIKKQEWKLEQLAADLSKYEQELYDL 474

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 861483604   433 QARVEMLENEQGQKE---AQLLGERSHFEEEKQQLASLITNLQSSI-------SNLSQAKEELEQASQ-AQGAKLNAQVA 501
Cdd:TIGR02169  475 KEEYDRVEKELSKLQrelAEAEAQARASEERVRGGRAVEEVLKASIqgvhgtvAQLGSVGERYATAIEvAAGNRLNNVVV 554

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 861483604   502 S---------------------------LTAELTTLSA------------------------------TLQQQDQELAGL 524
Cdd:TIGR02169  555 EddavakeaiellkrrkagratflplnkMRDERRDLSIlsedgvigfavdlvefdpkyepafkyvfgdTLVVEDIEAARR 634

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 861483604   525 KQQAQKKQAQLAQSLQQQEQASQGLRHQVEQLSGSLKQKEKQLEEAAR--ELDASRRDHAQQLATAAKAQETSLRERDAA 602
Cdd:TIGR02169  635 LMGKYRMVTLEGELFEKSGAMTGGSRAPRGGILFSRSEPAELQRLRERleGLKRELSSLQSELRRIENRLDELSQELSDA 714

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 861483604   603 CQQLEALEKEkaakLEILQQQLQAANEAQDSAQNSVTQAQREKAELSQKVEELHALIEAAHQEQCEAQTQVAALEARLKA 682
Cdd:TIGR02169  715 SRKIGEIEKE----IEQLEQEEEKLKERLEELEEDLSSLEQEIENVKSELKELEARIEELEEDLHKLEEALNDLEARLSH 790

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 861483604   683 EQQkaterEKVAQEKAQLQEQLWSLEESLKITKGSLEEEKCRAAAALEEhqhhISEMEAESRSLAEQHKQERKELEEEKA 762
Cdd:TIGR02169  791 SRI-----PEIQAELSKLEEEVSRIEARLREIEQKLNRLTLEKEYLEKE----IQELQEQRIDLKEQIKSIEKEIENLNG 861

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 861483604   763 KRRglgvQLQQLAETHQAETKALRQELAKartsnnmAEREVELLVKEVKTWRKRYEdsQQGETQYGLQEQLTTLKEEYEK 842
Cdd:TIGR02169  862 KKE----ELEEELEELEAALRDLESRLGD-------LKKERDELEAQLRELERKIE--ELEAQIEKKRKRLSELKAKLEA 928

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 861483604   843 SCQELRETKEKMAGIEAHS--ELQIGQHQSELAQLHANLA-------RALQQVQEKENRAQKLADDLSTLQEKMAATSKE 913
Cdd:TIGR02169  929 LEEELSEIEDPKGEDEEIPeeELSLEDVQAELQRVEEEIRalepvnmLAIQEYEEVLKRLDELKEKRAKLEEERKAILER 1008

                          810
                   ....*....|.
gi 861483604   914 VARLEALVRKA 924
Cdd:TIGR02169 1009 IEEYEKKKREV 1019
DUF3584 pfam12128
Protein of unknown function (DUF3584); This protein is found in bacteria and eukaryotes. ...
 331-898 1.64e-10

Protein of unknown function (DUF3584); This protein is found in bacteria and eukaryotes. Proteins in this family are typically between 943 to 1234 amino acids in length. This family contains a P-loop motif suggesting it is a nucleotide binding protein. It may be involved in replication.


Pssm-ID: 432349 [Multi-domain]  Cd Length: 1191  Bit Score: 66.79  E-value: 1.64e-10
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 861483604   331 ASNLQQLQGALNELTEEHSKATQQWVEKQAHLEKELSTALQDKKCLEEKNEIL-------------------------QG 385
Cdd:pfam12128  275 ASRQEERQETSAELNQLLRTLDDQWKEKRDELNGELSAADAAVAKDRSELEALedqhgafldadietaaadqeqlpswQS 354

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 861483604   386 KLSQLEERLAQLPESprQEKGEVLGDVLQLESLKQEAATLATNNTQL----QARVEMLENEQGQKEA-------QLLGER 454
Cdd:pfam12128  355 ELENLEERLKALTGK--HQDVTAKYNRRRSKIKEQNNRDIAGIKDKLakirEARDRQLAVAEDDLQAleselreQLEAGK 432

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 861483604   455 SHFEEEKQQLASLITNLQSSIS----------NLSQAKEELEQASQAQGAKlNAQVASLTAELTTLSATLQQQDQELAGL 524
Cdd:pfam12128  433 LEFNEEEYRLKSRLGELKLRLNqatatpelllQLENFDERIERAREEQEAA-NAEVERLQSELRQARKRRDQASEALRQA 511

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 861483604   525 KQQAQKKQAQLAQSLQQQEQASQGLRHQVEQLSGSLKQKEKQLeeAARELdASRRDHAQQLATAAKAQETSLRERDAACQ 604
Cdd:pfam12128  512 SRRLEERQSALDELELQLFPQAGTLLHFLRKEAPDWEQSIGKV--ISPEL-LHRTDLDPEVWDGSVGGELNLYGVKLDLK 588

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 861483604   605 QLEAleKEKAAKLEILQQQLQAANEAQDSAQNSVTQAQREKAELSQKVEELHALIEAAHQEQCEAQTQVAALEARLKAEQ 684
Cdd:pfam12128  589 RIDV--PEWAASEEELRERLDKAEEALQSAREKQAAAEEQLVQANGELEKASREETFARTALKNARLDLRRLFDEKQSEK 666

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 861483604   685 QKATerEKVAQEKAQLQEQLWSLEESLKitkgsleeekcraaAALEEHQHHISEMEAESRSLAEQHKQERKELEEEKAKR 764
Cdd:pfam12128  667 DKKN--KALAERKDSANERLNSLEAQLK--------------QLDKKHQAWLEEQKEQKREARTEKQAYWQVVEGALDAQ 730

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 861483604   765 RGLGVQ-LQQLAETHQAETKALRQELAKARTSNNMAEREVELLVKEVKTWRKRYEDSQQGE---TQYG--LQEQLTT--- 835
Cdd:pfam12128  731 LALLKAaIAARRSGAKAELKALETWYKRDLASLGVDPDVIAKLKREIRTLERKIERIAVRRqevLRYFdwYQETWLQrrp 810

                          570       580       590       600       610       620
                   ....*....|....*....|....*....|....*....|....*....|....*....|....
gi 861483604   836 -LKEEYEKSCQELRETKEKMAGIEAHSELQIGQHQSELAQLHANLARALQQVQEKENRAQKLAD 898
Cdd:pfam12128  811 rLATQLSNIERAISELQQQLARLIADTKLRRAKLEMERKASEKQQVRLSENLRGLRCEMSKLAT 874
SMC_prok_A TIGR02169
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of ...
 360-1101 3.67e-10

chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. It is found in a single copy and is homodimeric in prokaryotes, but six paralogs (excluded from this family) are found in eukarotes, where SMC proteins are heterodimeric. This family represents the SMC protein of archaea and a few bacteria (Aquifex, Synechocystis, etc); the SMC of other bacteria is described by TIGR02168. The N- and C-terminal domains of this protein are well conserved, but the central hinge region is skewed in composition and highly divergent. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274009 [Multi-domain]  Cd Length: 1164  Bit Score: 65.47  E-value: 3.67e-10
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 861483604   360 AHLEKELSTALQDKKCLEEKNEILQGKLSQLEERLAQLpespRQEKGEVLG-DVLQLESLKQEAatlatnnTQLQARVEM 438
Cdd:TIGR02169  166 AEFDRKKEKALEELEEVEENIERLDLIIDEKRQQLERL----RREREKAERyQALLKEKREYEG-------YELLKEKEA 234

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 861483604   439 LENEQGQKEAQLlgerSHFEEEKQQLASLITNLQSSISN----LSQAKEELEQASQAQGAKLNAQVASLTAELTTLSATL 514
Cdd:TIGR02169  235 LERQKEAIERQL----ASLEEELEKLTEEISELEKRLEEieqlLEELNKKIKDLGEEEQLRVKEKIGELEAEIASLERSI 310

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 861483604   515 QQQDQELaglkqqaqkkqAQLAQSLQQQEQASQGLRHQVEQLSGSLKQKEKQLEEAARELDASRrdhaqqlataakaqet 594
Cdd:TIGR02169  311 AEKEREL-----------EDAEERLAKLEAEIDKLLAEIEELEREIEEERKRRDKLTEEYAELK---------------- 363

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 861483604   595 slRERDAACQQLEALEKEKAA---KLEILQQQLQAANEAQDSAQNSVTQAQREKAELSQKVEELHALIEAAHQEQCEAQT 671
Cdd:TIGR02169  364 --EELEDLRAELEEVDKEFAEtrdELKDYREKLEKLKREINELKRELDRLQEELQRLSEELADLNAAIAGIEAKINELEE 441

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 861483604   672 QVAALEARLKAEQQKateREKVAQEKAQLQEQLWSLEESLKItkgsLEEEkcraaaaLEEHQHHISEMEAESRSLAEQHK 751
Cdd:TIGR02169  442 EKEDKALEIKKQEWK---LEQLAADLSKYEQELYDLKEEYDR----VEKE-------LSKLQRELAEAEAQARASEERVR 507

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 861483604   752 QERKELEEEKAKRRGLGVQLQQLAETHQAETKALrqELAKARTSNNM-------AEREVELLvKEVKTWR---------- 814
Cdd:TIGR02169  508 GGRAVEEVLKASIQGVHGTVAQLGSVGERYATAI--EVAAGNRLNNVvveddavAKEAIELL-KRRKAGRatflplnkmr 584

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 861483604   815 -------------------------KRYE-------------DSQQGETQYGLQEQLTTLKEE-YEKS------------ 843
Cdd:TIGR02169  585 derrdlsilsedgvigfavdlvefdPKYEpafkyvfgdtlvvEDIEAARRLMGKYRMVTLEGElFEKSgamtggsraprg 664

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 861483604   844 -----------CQELRETKEKMAGIEAHSELQIGQHQSELAQLHANLARALQQVQEKENRAQKLADD------------- 899
Cdd:TIGR02169  665 gilfsrsepaeLQRLRERLEGLKRELSSLQSELRRIENRLDELSQELSDASRKIGEIEKEIEQLEQEeeklkerleelee 744

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 861483604   900 -LSTLQEKMAATSKEVARLEAlvRKAGEQQETASLELLKEPPKTRDRESEWVE-EQQGQQLCSTQAALRAMEREAEQMGT 977
Cdd:TIGR02169  745 dLSSLEQEIENVKSELKELEA--RIEELEEDLHKLEEALNDLEARLSHSRIPEiQAELSKLEEEVSRIEARLREIEQKLN 822

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 861483604   978 ELEKLRAALMESQGQQQEERGQQEREVArltqERGQAEADLALEKAAKAELEMRLQNALNEQQAEFANLQEALSRALSEK 1057
Cdd:TIGR02169  823 RLTLEKEYLEKEIQELQEQRIDLKEQIK----SIEKEIENLNGKKEELEEELEELEAALRDLESRLGDLKKERDELEAQL 898

                          810       820       830       840
                   ....*....|....*....|....*....|....*....|....
gi 861483604  1058 EGKDQELSKLCEQEAVQRMELKELLQTVEQLKAQLAKKEKEQQQ 1101
Cdd:TIGR02169  899 RELERKIEELEAQIEKKRKRLSELKAKLEALEEELSEIEDPKGE 942
CCDC158 pfam15921
Coiled-coil domain-containing protein 158; CCDC158 is a family of proteins found in eukaryotes. ...
 234-984 5.86e-10

Coiled-coil domain-containing protein 158; CCDC158 is a family of proteins found in eukaryotes. The function is not known.


Pssm-ID: 464943 [Multi-domain]  Cd Length: 1112  Bit Score: 64.75  E-value: 5.86e-10
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 861483604   234 ELELAEHRKL------------LTEKDAQISMMQQRIDRLALLNEKQAASplepreleeLRGKNESLTFRLhetlkqcQD 301
Cdd:pfam15921   58 EVELDSPRKIiaypgkehiervLEEYSHQVKDLQRRLNESNELHEKQKFY---------LRQSVIDLQTKL-------QE 121

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 861483604   302 LKTEKGQMDRKINQLSEENGDLSFKLREFASNLQQLQGALNELTEEHSKATQQWVEKQAHLE---KELSTALQDKKCLEE 378
Cdd:pfam15921  122 MQMERDAMADIRRRESQSQEDLRNQLQNTVHELEAAKCLKEDMLEDSNTQIEQLRKMMLSHEgvlQEIRSILVDFEEASG 201

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 861483604   379 KNEILQGKLSQLEER---------LAQLPESPRQEKGEVLGDVLQLESLKQEAatlatnntqlQARVEMLENEQGQKEAQ 449
Cdd:pfam15921  202 KKIYEHDSMSTMHFRslgsaiskiLRELDTEISYLKGRIFPVEDQLEALKSES----------QNKIELLLQQHQDRIEQ 271

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 861483604   450 LLGER----SHFEEEKQQLASLITNLQSSISNLSQAKEELEQASQAQGAKLNAQVASLTAELTTLSATLQQQDQELAGLK 525
Cdd:pfam15921  272 LISEHeveiTGLTEKASSARSQANSIQSQLEIIQEQARNQNSMYMRQLSDLESTVSQLRSELREAKRMYEDKIEELEKQL 351

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 861483604   526 QQAQKKQAQLAQSLQQQEQASQGLRHQVEQLSGSLKQKEKQLE-EAARELDASRRDHAQQLATAAKAQEtsLRERDAACQ 604
Cdd:pfam15921  352 VLANSELTEARTERDQFSQESGNLDDQLQKLLADLHKREKELSlEKEQNKRLWDRDTGNSITIDHLRRE--LDDRNMEVQ 429

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 861483604   605 QLEALEK----EKAAKLEILQQQLQAANEAQDSAQNSVTQAQREKAELSQKVEELHA---LIEAAHQEQCEAQTQVAALE 677
Cdd:pfam15921  430 RLEALLKamksECQGQMERQMAAIQGKNESLEKVSSLTAQLESTKEMLRKVVEELTAkkmTLESSERTVSDLTASLQEKE 509

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 861483604   678 ARLKAEQQKATEREKVAQEKAQLQEQLWSLEESLKITKGSLE------EEKCRAAAALEEHQHHISEMEAESRSLAEQHK 751
Cdd:pfam15921  510 RAIEATNAEITKLRSRVDLKLQELQHLKNEGDHLRNVQTECEalklqmAEKDKVIEILRQQIENMTQLVGQHGRTAGAMQ 589

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 861483604   752 QERKELEEEKAKRRglgVQLQQL--------AETHQAETKALRQELAKARTSNNMAER---------EVELLVKEVKTWR 814
Cdd:pfam15921  590 VEKAQLEKEINDRR---LELQEFkilkdkkdAKIRELEARVSDLELEKVKLVNAGSERlravkdikqERDQLLNEVKTSR 666

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 861483604   815 KryedsqqgetqyglqeQLTTLKEEYEKSCQELRETKEKMAGIEAHSELQIGQHQSELAQLHanlaRALQQVQEKENRAQ 894
Cdd:pfam15921  667 N----------------ELNSLSEDYEVLKRNFRNKSEEMETTTNKLKMQLKSAQSELEQTR----NTLKSMEGSDGHAM 726

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 861483604   895 KLAddlSTLQEKMAATSKEVARLEalvrkageqqetASLELLKEPPKTRDRESEWVEEQQGQqlcsTQAALRAMEREAEQ 974
Cdd:pfam15921  727 KVA---MGMQKQITAKRGQIDALQ------------SKIQFLEEAMTNANKEKHFLKEEKNK----LSQELSTVATEKNK 787

                          810
                   ....*....|
gi 861483604   975 MGTELEKLRA 984
Cdd:pfam15921  788 MAGELEVLRS 797
SMC_N pfam02463
RecF/RecN/SMC N terminal domain; This domain is found at the N terminus of SMC proteins. The ...
 220-1049 7.85e-10

RecF/RecN/SMC N terminal domain; This domain is found at the N terminus of SMC proteins. The SMC (structural maintenance of chromosomes) superfamily proteins have ATP-binding domains at the N- and C-termini, and two extended coiled-coil domains separated by a hinge in the middle. The eukaryotic SMC proteins form two kind of heterodimers: the SMC1/SMC3 and the SMC2/SMC4 types. These heterodimers constitute an essential part of higher order complexes, which are involved in chromatin and DNA dynamics. This family also includes the RecF and RecN proteins that are involved in DNA metabolism and recombination.


Pssm-ID: 426784 [Multi-domain]  Cd Length: 1161  Bit Score: 64.61  E-value: 7.85e-10
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 861483604   220 KKQLADERNNRDELELELAEHRKLLTEKDAQISMMQQRIDRLALLNEKQAASPLEPRELEELRGKNESLTFRLHETLKQC 299
Cdd:pfam02463  180 EETENLAELIIDLEELKLQELKLKEQAKKALEYYQLKEKLELEEEYLLYLDYLKLNEERIDLLQELLRDEQEEIESSKQE 259

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 861483604   300 QDLKTEKGQMDRKINQLSEENGDLSFKLREFASNLQQLQGALNELTEEHSKATQqwvEKQAHLEKELSTALQDKKCLEEK 379
Cdd:pfam02463  260 IEKEEEKLAQVLKENKEEEKEKKLQEEELKLLAKEEEELKSELLKLERRKVDDE---EKLKESEKEKKKAEKELKKEKEE 336

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 861483604   380 NEILQGKLSQLEERLAQLpespRQEKGEVLGDVLQLESLKQEAATLATNNTQLQARVEMLENEQGQKEAQLLGERSHFEE 459
Cdd:pfam02463  337 IEELEKELKELEIKREAE----EEEEEELEKLQEKLEQLEEELLAKKKLESERLSSAAKLKEEELELKSEEEKEAQLLLE 412

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 861483604   460 EKQQLASLITNLQSSISNLSQAKEELEQASQAQGAKLNAQVASLTAELTTLSATLQQQDQELAGLKQQAQKKQAQLAQSL 539
Cdd:pfam02463  413 LARQLEDLLKEEKKEELEILEEEEESIELKQGKLTEEKEELEKQELKLLKDELELKKSEDLLKETQLVKLQEQLELLLSR 492

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 861483604   540 QQQEQASQGLRHQVEQLSGSLKQKEKQLEEAARELDASRRDHAQQLATAAKAQETS-LRERDAACQQLEALEKEKAAKLE 618
Cdd:pfam02463  493 QKLEERSQKESKARSGLKVLLALIKDGVGGRIISAHGRLGDLGVAVENYKVAISTAvIVEVSATADEVEERQKLVRALTE 572

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 861483604   619 ILQQQLQAANEAQDSAQNSVTQAQREKAELSQKVEELHALIEAAHQEQCEAQTQVAALEARLKAEQQKATEREKVAQEKA 698
Cdd:pfam02463  573 LPLGARKLRLLIPKLKLPLKSIAVLEIDPILNLAQLDKATLEADEDDKRAKVVEGILKDTELTKLKESAKAKESGLRKGV 652

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 861483604   699 QLQEqlWSLEESLKITKGSLEEEKCRAAAALEEHQHHISEMEAESRSLAEQHKQERKELEEEKAKRrgLGVQLQQLAETH 778
Cdd:pfam02463  653 SLEE--GLAEKSEVKASLSELTKELLEIQELQEKAESELAKEEILRRQLEIKKKEQREKEELKKLK--LEAEELLADRVQ 728

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 861483604   779 QAETKALRQELAKARTSNNMAEREVELLVKEVKTWRKRYEDSQQGETQYGLQEQLTTLKEEYEKSCQELRETKEKMAGIE 858
Cdd:pfam02463  729 EAQDKINEELKLLKQKIDEEEEEEEKSRLKKEEKEEEKSELSLKEKELAEEREKTEKLKVEEEKEEKLKAQEEELRALEE 808

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 861483604   859 AHSELQIGQHQSELAQLHANLARALQQVQEKENraQKLADDLSTLQEKMAATSKEVARLEALVRKAGEQQETASLELLKE 938
Cdd:pfam02463  809 ELKEEAELLEEEQLLIEQEEKIKEEELEELALE--LKEEQKLEKLAEEELERLEEEITKEELLQELLLKEEELEEQKLKD 886

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 861483604   939 PPKTRDRESEWVEEQQGQQLCSTQAALRAMEREAEQMGTELEKLRAAL-MESQGQQQEERGQQEREVARLTQERGQAEAD 1017
Cdd:pfam02463  887 ELESKEEKEKEEKKELEEESQKLNLLEEKENEIEERIKEEAEILLKYEeEPEELLLEEADEKEKEENNKEEEEERNKRLL 966

                          810       820       830
                   ....*....|....*....|....*....|..
gi 861483604  1018 LALEKAAKAELEMRLQNALNEQQAEFANLQEA 1049
Cdd:pfam02463  967 LAKEELGKVNLMAIEEFEEKEERYNKDELEKE 998
DUF3584 pfam12128
Protein of unknown function (DUF3584); This protein is found in bacteria and eukaryotes. ...
 601-1129 1.26e-09

Protein of unknown function (DUF3584); This protein is found in bacteria and eukaryotes. Proteins in this family are typically between 943 to 1234 amino acids in length. This family contains a P-loop motif suggesting it is a nucleotide binding protein. It may be involved in replication.


Pssm-ID: 432349 [Multi-domain]  Cd Length: 1191  Bit Score: 63.70  E-value: 1.26e-09
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 861483604   601 AACQQLEALEKEKAA-KLEILQQQLQAAN--EAQDSAQNSVTQAQREK-AELSQKVEELHALIEAAHQEQCEAQTQVAAL 676
Cdd:pfam12128  248 QEFNTLESAELRLSHlHFGYKSDETLIASrqEERQETSAELNQLLRTLdDQWKEKRDELNGELSAADAAVAKDRSELEAL 327

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 861483604   677 EARLKAEQQKATEREKVAQEKA-QLQEQLWSLEESLKitkgsleeekcraaAALEEHQHHISEMEAESRSLAEQHKQERK 755
Cdd:pfam12128  328 EDQHGAFLDADIETAAADQEQLpSWQSELENLEERLK--------------ALTGKHQDVTAKYNRRRSKIKEQNNRDIA 393

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 861483604   756 ELEEEKAKRRGLGVQLQQLAETH-QAETKALRQELAKARTSNNMAEREVELLVKEVKTwrkryedsQQGETQYglQEQLT 834
Cdd:pfam12128  394 GIKDKLAKIREARDRQLAVAEDDlQALESELREQLEAGKLEFNEEEYRLKSRLGELKL--------RLNQATA--TPELL 463

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 861483604   835 TLKEEYEKSCQELRETKEK-MAGIEAHselqigqhQSELAQLHANLARALQQVQEKENRAQKLADDLSTLQEKMAATSKE 913
Cdd:pfam12128  464 LQLENFDERIERAREEQEAaNAEVERL--------QSELRQARKRRDQASEALRQASRRLEERQSALDELELQLFPQAGT 535

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 861483604   914 VarLEALVRKAGEQQETASLELLKEPPKTRDRESEWVEEQQGQQLCSTQAALRAMEREAE---QMGTELEKLRAALMESQ 990
Cdd:pfam12128  536 L--LHFLRKEAPDWEQSIGKVISPELLHRTDLDPEVWDGSVGGELNLYGVKLDLKRIDVPewaASEEELRERLDKAEEAL 613

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 861483604   991 GQQQEERGQQEREVARLTQERGQAEADLALEKAAKAELEMRLQNALNEQQAEFANLQEALSRalsEKEGKDQELSKLceq 1070
Cdd:pfam12128  614 QSAREKQAAAEEQLVQANGELEKASREETFARTALKNARLDLRRLFDEKQSEKDKKNKALAE---RKDSANERLNSL--- 687

                          490       500       510       520       530
                   ....*....|....*....|....*....|....*....|....*....|....*....
gi 861483604  1071 EAVQRMELKELLQTVEQLKAQLAKKEKEQQQSARGASGENASGMGTQSEAVGKMEALRA 1129
Cdd:pfam12128  688 EAQLKQLDKKHQAWLEEQKEQKREARTEKQAYWQVVEGALDAQLALLKAAIAARRSGAK 746
Mplasa_alph_rch TIGR04523
helix-rich Mycoplasma protein; Members of this family occur strictly within a subset of ...
 217-715 1.34e-09

helix-rich Mycoplasma protein; Members of this family occur strictly within a subset of Mycoplasma species. Members average 750 amino acids in length, including signal peptide. Sequences are predicted (Jpred 3) to be almost entirely alpha-helical. These sequences show strong periodicity (consistent with long alpha helical structures) and low complexity rich in D,E,N,Q, and K. Genes encoding these proteins are often found in tandem. The function is unknown.


Pssm-ID: 275316 [Multi-domain]  Cd Length: 745  Bit Score: 63.50  E-value: 1.34e-09
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 861483604   217 RRLKKQLADERNNRDELELELAEHRKLLTEKDAQISMMQQRIDRLALLNEKQAaspLEPRELEELRGKNESLTFRLHETL 296
Cdd:TIGR04523  162 NDLKKQKEELENELNLLEKEKLNIQKNIDKIKNKLLKLELLLSNLKKKIQKNK---SLESQISELKKQNNQLKDNIEKKQ 238

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 861483604   297 KQCQDLKTEKGQMDRKINQLSEENGDLSFKLREFASNLQQLQGALNELTEEHSKATQQWV----EKQAHLEKELSTALQD 372
Cdd:TIGR04523  239 QEINEKTTEISNTQTQLNQLKDEQNKIKKQLSEKQKELEQNNKKIKELEKQLNQLKSEISdlnnQKEQDWNKELKSELKN 318

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 861483604   373 KkclEEKNEILQGKLSQLEERLAQLPEsprqekgevlgdvlQLESLKQEAATLATNNTQLQARVEmlenEQGQKEAQLLG 452
Cdd:TIGR04523  319 Q---EKKLEEIQNQISQNNKIISQLNE--------------QISQLKKELTNSESENSEKQRELE----EKQNEIEKLKK 377

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 861483604   453 ERSHFEEEKQQLASLITNLQSSISNLSQAKEELEQ---ASQAQGAKLNAQVASLTAELTTLSAT---LQQQDQELAGLKQ 526
Cdd:TIGR04523  378 ENQSYKQEIKNLESQINDLESKIQNQEKLNQQKDEqikKLQQEKELLEKEIERLKETIIKNNSEikdLTNQDSVKELIIK 457

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 861483604   527 QAQKKQAQLAQSLQQQEQASQGLRHQVEQLSGSLKQKEKQLEeaarELDASRRDHAQQLATAAKAQETSLRERdaacQQL 606
Cdd:TIGR04523  458 NLDNTRESLETQLKVLSRSINKIKQNLEQKQKELKSKEKELK----KLNEEKKELEEKVKDLTKKISSLKEKI----EKL 529

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 861483604   607 EALEKEKAAKLEILQQQLQAANEAQDSaqnsvTQAQREKAELSQKVEELHALIEAAHQEQCEAQTQVaalearlkaeQQK 686
Cdd:TIGR04523  530 ESEKKEKESKISDLEDELNKDDFELKK-----ENLEKEIDEKNKEIEELKQTQKSLKKKQEEKQELI----------DQK 594

                          490       500
                   ....*....|....*....|....*....
gi 861483604   687 ATEREKVAQEKAQLQEQLWSLEESLKITK 715
Cdd:TIGR04523  595 EKEKKDLIKEIEEKEKKISSLEKELEKAK 623
MARTX_Nterm NF012221
MARTX multifunctional-autoprocessing repeats-in-toxin holotoxin N-terminal region; This model ...
 406-651 2.34e-09

MARTX multifunctional-autoprocessing repeats-in-toxin holotoxin N-terminal region; This model describes the N-terminal 1900 amino acids of MARTX family multifunctional-autoprocessing repeats-in-toxin holotoxins, which contain both repeat regions that facilitate their entry into eukaryotic target cells, and multiple effector domains.


Pssm-ID: 467957 [Multi-domain]  Cd Length: 1848  Bit Score: 62.93  E-value: 2.34e-09
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 861483604  406 GEVLGDVLQLESLKQEAATLATNNTQLQARVEMLeNEQGQKEAqllgERSHFEEEKQQLASLITNLQSSISNLSQAKeeL 485
Cdd:NF012221 1528 GYILDNVVATSESSQQADAVSKHAKQDDAAQNAL-ADKERAEA----DRQRLEQEKQQQLAAISGSQSQLESTDQNA--L 1600

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 861483604  486 EQASQAQGAKLNAQVASLTAELTTLSATL-----QQQDQELAGLKQQAQKKQAQLAQSLQQQEQASQGLRHQVEQLSGSL 560
Cdd:NF012221 1601 ETNGQAQRDAILEESRAVTKELTTLAQGLdaldsQATYAGESGDQWRNPFAGGLLDRVQEQLDDAKKISGKQLADAKQRH 1680

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 861483604  561 KQKEKQLEEAARELDA--SRRDHAQQLATAAKAQ---ETSLRERDAACQQLEALEKEKAAKLEILQQQlQAANEAQDSAQ 635
Cdd:NF012221 1681 VDNQQKVKDAVAKSEAgvAQGEQNQANAEQDIDDakaDAEKRKDDALAKQNEAQQAESDANAAANDAQ-SRGEQDASAAE 1759

                         250
                  ....*....|....*.
gi 861483604  636 NSVTQAQREKAELSQK 651
Cdd:NF012221 1760 NKANQAQADAKGAKQD 1775
PRK02224 PRK02224
DNA double-strand break repair Rad50 ATPase;
441-930 2.53e-09

DNA double-strand break repair Rad50 ATPase;


Pssm-ID: 179385 [Multi-domain]  Cd Length: 880  Bit Score: 62.75  E-value: 2.53e-09
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 861483604  441 NEQGQKEAQLLGERSHFEEEKQQLASLITNLQSSISNLSQAKEELEQASQAQgAKLNAQVASLTAELTTLSATLQQQDQ- 519
Cdd:PRK02224  209 NGLESELAELDEEIERYEEQREQARETRDEADEVLEEHEERREELETLEAEI-EDLRETIAETEREREELAEEVRDLREr 287

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 861483604  520 ---------ELAGLKQQAQKKQAQLAQSLQQQEQASQGLRHQVEQLSGSLKQKEKQLE---EAARELD---ASRRDHAQQ 584
Cdd:PRK02224  288 leeleeerdDLLAEAGLDDADAEAVEARREELEDRDEELRDRLEECRVAAQAHNEEAEslrEDADDLEeraEELREEAAE 367

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 861483604  585 LATAAKAQETSLRERDAacqQLEALEKE----------KAAKLEILQQQLQAANEAQDSAQNSVTQAQREKAELSQKVEE 654
Cdd:PRK02224  368 LESELEEAREAVEDRRE---EIEELEEEieelrerfgdAPVDLGNAEDFLEELREERDELREREAELEATLRTARERVEE 444

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 861483604  655 LHALIEAAHQEQC----EAQTQVAALEARLKAEQQKATEREKVAQEKAQLQEQLWSLEESLKITKG--SLEEEKCRAAAA 728
Cdd:PRK02224  445 AEALLEAGKCPECgqpvEGSPHVETIEEDRERVEELEAELEDLEEEVEEVEERLERAEDLVEAEDRieRLEERREDLEEL 524

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 861483604  729 LEEHQHHIsemeAESRSLAEQHKQERKELEEEKAKRRGLGVQLQQLAETHQAETKALRQELAKARTSNNMAEREVELLVk 808
Cdd:PRK02224  525 IAERRETI----EEKRERAEELRERAAELEAEAEEKREAAAEAEEEAEEAREEVAELNSKLAELKERIESLERIRTLLA- 599

                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 861483604  809 evktwrKRYEDSQQGETQYGLQEQLTTLKEEYEKSCQELRETKEKMAgiEAHSELQIGQHQSELAQLH---ANLARALQQ 885
Cdd:PRK02224  600 ------AIADAEDEIERLREKREALAELNDERRERLAEKRERKRELE--AEFDEARIEEAREDKERAEeylEQVEEKLDE 671

                         490       500       510       520       530
                  ....*....|....*....|....*....|....*....|....*....|..
gi 861483604  886 VQEKENRAQKLA-------DDLSTLQEKMAATSKEVARLEALVRKAGEQQET 930
Cdd:PRK02224  672 LREERDDLQAEIgavenelEELEELRERREALENRVEALEALYDEAEELESM 723
COG4913 COG4913
Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];
1226-1698 3.27e-09

Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];


Pssm-ID: 443941 [Multi-domain]  Cd Length: 1089  Bit Score: 62.24  E-value: 3.27e-09
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 861483604 1226 GSLISSLEEEVSILNR--QVLEKEGESKELKRLVIAESEKSQKLEERLRLLQ-METASNSARAAERSSALREEVQSLREE 1302
Cdd:COG4913   224 FEAADALVEHFDDLERahEALEDAREQIELLEPIRELAERYAAARERLAELEyLRAALRLWFAQRRLELLEAELEELRAE 303

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 861483604 1303 VEKQRAASENLRQELASQAERAEEL--------GQELKAWQEKFFQKEQALSALQLEHTSTQALVSELlpakhlcqQLQA 1374
Cdd:COG4913   304 LARLEAELERLEARLDALREELDELeaqirgngGDRLEQLEREIERLERELEERERRRARLEALLAAL--------GLPL 375

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 861483604 1375 EQVAAE-KRHREELEQSKQAAGGLRTELMRAQRElgelvpLRQKVAEQERAAQQLRAEKAS-----------YAEQLSML 1442
Cdd:COG4913   376 PASAEEfAALRAEAAALLEALEEELEALEEALAE------AEAALRDLRRELRELEAEIASlerrksniparLLALRDAL 449

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 861483604 1443 KKAHGLLAEENRGLGEranlgrqFLEVELDQAR-----EKYI-----------QELAAVRGDAETRLAEMR---QEVQST 1503
Cdd:COG4913   450 AEALGLDEAELPFVGE-------LIEVRPEEERwrgaiERVLggfaltllvppEHYAAALRWVNRLHLRGRlvyERVRTG 522

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 861483604 1504 THELEVMTAKYEGAKVKVLEERQRFQE------ERQKLTAQVEQLEVFQRE--------QTKKVEEL-SKKLADYDQASK 1568
Cdd:COG4913   523 LPDPERPRLDPDSLAGKLDFKPHPFRAwleaelGRRFDYVCVDSPEELRRHpraitragQVKGNGTRhEKDDRRRIRSRY 602

                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 861483604 1569 V----QQQKLKAFQAQGGESQQEAQRLQTQLNELQVQLSQKEQAAEHYK---------VQMEKAKTHYDAKKQQNQELQE 1635
Cdd:COG4913   603 VlgfdNRAKLAALEAELAELEEELAEAEERLEALEAELDALQERREALQrlaeyswdeIDVASAEREIAELEAELERLDA 682

                         490       500       510       520       530       540
                  ....*....|....*....|....*....|....*....|....*....|....*....|...
gi 861483604 1636 QLQGLEQLQKENKELRAEAERLGQELQQAGLKTKEAEQTCRHLTAQVRSLEAQVAHADQQLRE 1698
Cdd:COG4913   683 SSDDLAALEEQLEELEAELEELEEELDELKGEIGRLEKELEQAEEELDELQDRLEAAEDLARL 745
SMC_prok_A TIGR02169
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of ...
 276-1088 3.83e-09

chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. It is found in a single copy and is homodimeric in prokaryotes, but six paralogs (excluded from this family) are found in eukarotes, where SMC proteins are heterodimeric. This family represents the SMC protein of archaea and a few bacteria (Aquifex, Synechocystis, etc); the SMC of other bacteria is described by TIGR02168. The N- and C-terminal domains of this protein are well conserved, but the central hinge region is skewed in composition and highly divergent. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274009 [Multi-domain]  Cd Length: 1164  Bit Score: 62.39  E-value: 3.83e-09
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 861483604   276 RELEELRGKNESLTFRLHETLKQCQDLKTEKG--------------------------------QMDRKINQLSEENGDL 323
Cdd:TIGR02169  177 EELEEVEENIERLDLIIDEKRQQLERLRREREkaeryqallkekreyegyellkekealerqkeAIERQLASLEEELEKL 256

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 861483604   324 SFKLREFASNLQQLQGALNELTEEHSKATQqwvEKQAHLEKELSTALQDKKCLEEKNEILQGKLSQLEERLAQLPESPRQ 403
Cdd:TIGR02169  257 TEEISELEKRLEEIEQLLEELNKKIKDLGE---EEQLRVKEKIGELEAEIASLERSIAEKERELEDAEERLAKLEAEIDK 333

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 861483604   404 EKGEVLGDVLQLESLKQEAATLATNNTQLQARVEMLENEQGQKEAQLLGERSHFEEEKQQLASLITNLQSSISNLSQAKE 483
Cdd:TIGR02169  334 LLAEIEELEREIEEERKRRDKLTEEYAELKEELEDLRAELEEVDKEFAETRDELKDYREKLEKLKREINELKRELDRLQE 413

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 861483604   484 ELEQASQaQGAKLNAQVASLTAELTTLSATLQQQDQELAglkqqaqkkqaQLAQSLQQQEQASQGLRHQVEQLSGSLKQK 563
Cdd:TIGR02169  414 ELQRLSE-ELADLNAAIAGIEAKINELEEEKEDKALEIK-----------KQEWKLEQLAADLSKYEQELYDLKEEYDRV 481

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 861483604   564 EKQLEEAARELDA--SRRDHAQQLATAAKAQETSLRERD----AACQQLEALEKEKAAKLEI-LQQQLQAANEAQDS-AQ 635
Cdd:TIGR02169  482 EKELSKLQRELAEaeAQARASEERVRGGRAVEEVLKASIqgvhGTVAQLGSVGERYATAIEVaAGNRLNNVVVEDDAvAK 561

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 861483604   636 NSVTQAQREKAELS-----QKVEELHALIEAAHQE----------QCEAQTQVA---ALEARLKAEQQKATEREKVAQEK 697
Cdd:TIGR02169  562 EAIELLKRRKAGRAtflplNKMRDERRDLSILSEDgvigfavdlvEFDPKYEPAfkyVFGDTLVVEDIEAARRLMGKYRM 641

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 861483604   698 AQLQEQLwsLEESLKITKGSleeekcRAAAALEEHQHHISEMEAESRSLAEQHKQERKELEEEKAKRRGLGVQLQQLAET 777
Cdd:TIGR02169  642 VTLEGEL--FEKSGAMTGGS------RAPRGGILFSRSEPAELQRLRERLEGLKRELSSLQSELRRIENRLDELSQELSD 713

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 861483604   778 HQAETKALRQELakartsnNMAEREVELLVKEVKTWRKRYEDSQQGETQYglQEQLTTLKEEYEKSCQELRETKEKMAGI 857
Cdd:TIGR02169  714 ASRKIGEIEKEI-------EQLEQEEEKLKERLEELEEDLSSLEQEIENV--KSELKELEARIEELEEDLHKLEEALNDL 784

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 861483604   858 EAH-SELQIGQHQSELAQLHANLARALQQVQEKENRAQKLADDLSTLQEKMAatSKEVARLEALVRKAGEQQETASLELL 936
Cdd:TIGR02169  785 EARlSHSRIPEIQAELSKLEEEVSRIEARLREIEQKLNRLTLEKEYLEKEIQ--ELQEQRIDLKEQIKSIEKEIENLNGK 862

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 861483604   937 KEPPKTRDRESEWVEEQQGQQLC-------STQAALRAMEREAEQMGTELEKLRAALMESQGQQQEERGQQEREVARLTQ 1009
Cdd:TIGR02169  863 KEELEEELEELEAALRDLESRLGdlkkerdELEAQLRELERKIEELEAQIEKKRKRLSELKAKLEALEEELSEIEDPKGE 942

                          810       820       830       840       850       860       870
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 861483604  1010 ERGQAEADLALEKaakaelemrLQNALNEQQAEFANLQEALSRALSEKEGKDQELSKLCEQEAVQRMELKELLQTVEQL 1088
Cdd:TIGR02169  943 DEEIPEEELSLED---------VQAELQRVEEEIRALEPVNMLAIQEYEEVLKRLDELKEKRAKLEEERKAILERIEEY 1012
PRK03918 PRK03918
DNA double-strand break repair ATPase Rad50;
1038-1568 8.14e-09

DNA double-strand break repair ATPase Rad50;


Pssm-ID: 235175 [Multi-domain]  Cd Length: 880  Bit Score: 60.85  E-value: 8.14e-09
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 861483604 1038 EQQAEFANLQEALSRALSEKEGKDQELSKLCEQEAVQRMELKELLQTVEQLKAQLAKKEKEQQQSARGASGENASGMGTQ 1117
Cdd:PRK03918  186 KRTENIEELIKEKEKELEEVLREINEISSELPELREELEKLEKEVKELEELKEEIEELEKELESLEGSKRKLEEKIRELE 265

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 861483604 1118 S---EAVGKMEALRAKVSKLEQQCQQQQEEadslaRSLESERAFHVERDRALETLQGQLEEKARELGYSQAASASAQREL 1194
Cdd:PRK03918  266 ErieELKKEIEELEEKVKELKELKEKAEEY-----IKLSEFYEEYLDELREIEKRLSRLEEEINGIEERIKELEEKEERL 340

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 861483604 1195 ATLRAKAQDHSKAEEEWKAQVaRGQQEAVRKGSLISSLEEEVSILNRQVLEKEGESKELKRLVIAESEKsqKLEERLRLL 1274
Cdd:PRK03918  341 EELKKKLKELEKRLEELEERH-ELYEEAKAKKEELERLKKRLTGLTPEKLEKELEELEKAKEEIEEEIS--KITARIGEL 417

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 861483604 1275 -----QMETASNSARAAERSSAL--REEVQSLREEV-EKQRAASENLRQELASQAERAEELGQELKAWqEKFFQKEQALS 1346
Cdd:PRK03918  418 kkeikELKKAIEELKKAKGKCPVcgRELTEEHRKELlEEYTAELKRIEKELKEIEEKERKLRKELREL-EKVLKKESELI 496

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 861483604 1347 ALQlehtstqALVSELLPAKHLCQQLQAEQVAAEKrhrEELEQSKQAAGGLRTELMRAQRELGELVPLRQKVAEQERAAQ 1426
Cdd:PRK03918  497 KLK-------ELAEQLKELEEKLKKYNLEELEKKA---EEYEKLKEKLIKLKGEIKSLKKELEKLEELKKKLAELEKKLD 566

                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 861483604 1427 QLRAEKASYAEQLSmlKKAHGLLAEENRGLGERANLGRQFLEVeldQAREKYIQELAAVRGDAETRLAEMRQEVQSTTHE 1506
Cdd:PRK03918  567 ELEEELAELLKELE--ELGFESVEELEERLKELEPFYNEYLEL---KDAEKELEREEKELKKLEEELDKAFEELAETEKR 641

                         490       500       510       520       530       540       550
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 861483604 1507 LEVMTAKYEGAKVKVLEERQRFQEER--------QKLTAQVEQLEVFQREQTKKVEELSKKLADYDQASK 1568
Cdd:PRK03918  642 LEELRKELEELEKKYSEEEYEELREEylelsrelAGLRAELEELEKRREEIKKTLEKLKEELEEREKAKK 711
HkD_SF cd22211
Hook domain-containing proteins superfamily; The Hook domain superfamily includes Hook adaptor ...
 8-136 2.21e-08

Hook domain-containing proteins superfamily; The Hook domain superfamily includes Hook adaptor proteins, Hook-related proteins and nuclear mitotic apparatus protein (NuMA). They share an N-terminal conserved globular Hook domain, which folds as a variant of the helical calponin homology (CH) domain with an extended alpha-helix. The Hook domain is responsible for the binding of microtubule. The Hook family includes microtubule-binding proteins, Hook1-3. Hook1 is required for spermatid differentiation. Hook2 contributes to the establishment and maintenance of centrosome function. Hook3 is an adaptor protein for microtubule-dependent intracellular vesicle and protein trafficking, and is involved in Golgi and endosome transport. Hook proteins are components of the FTS/Hook/FHIP complex (FHF complex), which may function to promote vesicle trafficking and/or fusion via the homotypic vesicular protein sorting (HOPS) complex. The Hook-related protein (HkRP) family includes Daple, Girdin and Gipie. Daple, also called Dvl-associating protein with a high frequency of leucine residues, or coiled-coil domain-containing protein 88C(CCDC88C), or Hook-related protein 2 (HkRP2), is a novel non-receptor nucleotide exchange factor (GEF) required for activation of guanine nucleotide-binding proteins (G-proteins) during non-canonical Wnt signaling. Girdin, also called Akt phosphorylation enhancer (APE), or coiled-coil domain-containing protein 88A (CCDC88A), or G alpha-interacting vesicle-associated protein (GIV), or Girders of actin filament, or Hook-related protein 1 (HkRP1), is a bifunctional modulator of guanine nucleotide-binding proteins (G proteins). Gipie, also called GRP78-interacting protein induced by ER stress, or coiled-coil domain-containing protein 88B(CCDC88B), or brain leucine zipper domain-containing protein, or Hook-related protein 3 (HkRP3), is a novel actin cytoskeleton-binding protein and Akt substrate that regulates cell migratory responses in various biological contexts. NuMA, also called nuclear mitotic apparatus protein 1, or nuclear matrix protein-22 (NMP-22), or SP-H antigen, is a microtubule (MT)-binding protein that plays a role in the formation and maintenance of the spindle poles and the alignment and the segregation of chromosomes during mitotic cell division.


Pssm-ID: 411792  Cd Length: 145  Bit Score: 54.97  E-value: 2.21e-08
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 861483604    8 AAALLSWVNSLRVADLVEAVPQLQDCSVFIKIIDGIRGTEEGQQILQQPVP--------ERLDFVCSFLQKNR----KRP 75
Cdd:cd22211     1 EAALLAWINTFPLSSPVESLDDLSDGVVLAEILSQIDPSYFDSEWLESRDSsdnwvlklNNLKKLYRSLSKYYrevlGQQ 80

                          90       100       110       120       130       140
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 861483604   76 SSPECLVSMQKVME-GSELELAKIIMLLLYHSSMSSQNLRD---WEQFEYRIQAELAVILKFMLD 136
Cdd:cd22211    81 LSDLPLPDLSAIARdGDEEEIVKLLELVLGAAVQCENKEEYiarIQQLDESTQAELMLIIQEVLE 145
COG4913 COG4913
Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];
829-1407 2.24e-08

Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];


Pssm-ID: 443941 [Multi-domain]  Cd Length: 1089  Bit Score: 59.54  E-value: 2.24e-08
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 861483604  829 LQEQLTTLkEEYEKSCQELRETKEKMAGIEAHSElQIGQHQSELAQL-----HANLARALQQVQEKENRAQKLADDLSTL 903
Cdd:COG4913   230 LVEHFDDL-ERAHEALEDAREQIELLEPIRELAE-RYAAARERLAELeylraALRLWFAQRRLELLEAELEELRAELARL 307

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 861483604  904 QEKMAATSKEVARLEALVRKAGEQQETASLELLkeppktrdresewveEQQGQQLCSTQAALRAMEREAEQMGTELEKLR 983
Cdd:COG4913   308 EAELERLEARLDALREELDELEAQIRGNGGDRL---------------EQLEREIERLERELEERERRRARLEALLAALG 372

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 861483604  984 AALMESQGQQQEERGQQEREVARLTQERGQAEADLALEKAAKAELEMRLQNALNEQQ----------AEFANLQEALSRA 1053
Cdd:COG4913   373 LPLPASAEEFAALRAEAAALLEALEEELEALEEALAEAEAALRDLRRELRELEAEIAslerrksnipARLLALRDALAEA 452

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 861483604 1054 LSEKEGkdqELSKLCEqeavqrmelkeLLQtveqlkaqLAKKEKEQQQSARGASGENASGM----GTQSEAVGKMEALR- 1128
Cdd:COG4913   453 LGLDEA---ELPFVGE-----------LIE--------VRPEEERWRGAIERVLGGFALTLlvppEHYAAALRWVNRLHl 510

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 861483604 1129 ------AKVSKLEQQCQQQQEEADSLARSLESERafHVERDRALETLQGQLE----EKAREL-GYSQAASASAQRELATL 1197
Cdd:COG4913   511 rgrlvyERVRTGLPDPERPRLDPDSLAGKLDFKP--HPFRAWLEAELGRRFDyvcvDSPEELrRHPRAITRAGQVKGNGT 588

                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 861483604 1198 RAKAQDHSKAEEEW------KAQVARGQQEAVRkgslissLEEEVSILNRQVLEKEGESKELKRLVIAESEKSQKLEERL 1271
Cdd:COG4913   589 RHEKDDRRRIRSRYvlgfdnRAKLAALEAELAE-------LEEELAEAEERLEALEAELDALQERREALQRLAEYSWDEI 661

                         490       500       510       520       530       540       550       560
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 861483604 1272 RLLQMETASnsARAAERSSALRE---EVQSLREEVEKQRAASENLRQELASQAERAEELGQELKAWQEkffqkEQALSAL 1348
Cdd:COG4913   662 DVASAEREI--AELEAELERLDAssdDLAALEEQLEELEAELEELEEELDELKGEIGRLEKELEQAEE-----ELDELQD 734

                         570       580       590       600       610       620
                  ....*....|....*....|....*....|....*....|....*....|....*....|.
gi 861483604 1349 QLEHTSTQALVSELLPAKHLCQQLQAEQVAAEKRHR--EELEQSKQAAGGLRTELMRAQRE 1407
Cdd:COG4913   735 RLEAAEDLARLELRALLEERFAAALGDAVERELRENleERIDALRARLNRAEEELERAMRA 795
sbcc TIGR00618
exonuclease SbcC; All proteins in this family for which functions are known are part of an ...
 312-988 2.27e-08

exonuclease SbcC; All proteins in this family for which functions are known are part of an exonuclease complex with sbcD homologs. This complex is involved in the initiation of recombination to regulate the levels of palindromic sequences in DNA. This family is based on the phylogenomic analysis of JA Eisen (1999, Ph.D. Thesis, Stanford University). [DNA metabolism, DNA replication, recombination, and repair]


Pssm-ID: 129705 [Multi-domain]  Cd Length: 1042  Bit Score: 59.60  E-value: 2.27e-08
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 861483604   312 KINQLSEENGDLSFKLREFASNLQQLQGALNELTEEHSKATQQWVEKQAHLEKELSTALQDKKCLEEKneiLQGKLSQLE 391
Cdd:TIGR00618  177 QYTQLALMEFAKKKSLHGKAELLTLRSQLLTLCTPCMPDTYHERKQVLEKELKHLREALQQTQQSHAY---LTQKREAQE 253

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 861483604   392 ERLaqlpeSPRQEKGEVLGdvlQLESLKQEAATLATNNTQLqarvemlenEQGQKEAQLLGERSHFEEEKQQLASLITNL 471
Cdd:TIGR00618  254 EQL-----KKQQLLKQLRA---RIEELRAQEAVLEETQERI---------NRARKAAPLAAHIKAVTQIEQQAQRIHTEL 316

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 861483604   472 QSSISNLSQAKEElEQASQAQGAKLNAQVASLTAELTTLSATLQQQDQELAGLKQQAQKKQAQLAQSLQQQEQASQglrH 551
Cdd:TIGR00618  317 QSKMRSRAKLLMK-RAAHVKQQSSIEEQRRLLQTLHSQEIHIRDAHEVATSIREISCQQHTLTQHIHTLQQQKTTL---T 392

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 861483604   552 QVEQLSGSLKQKEKQLEEAARELDASRRDHAQQLAtAAKAQETSLRERDAACQQLEALEKEKAAKLEILQQQLQAANEAQ 631
Cdd:TIGR00618  393 QKLQSLCKELDILQREQATIDTRTSAFRDLQGQLA-HAKKQQELQQRYAELCAAAITCTAQCEKLEKIHLQESAQSLKER 471

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 861483604   632 dsaqnsvTQAQREKAELSQKVEELHALIEAAHQEQCEAQTQVAALEARLKAEQQKATEREKVAQEKAQLQEQLWSLEESL 711
Cdd:TIGR00618  472 -------EQQLQTKEQIHLQETRKKAVVLARLLELQEEPCPLCGSCIHPNPARQDIDNPGPLTRRMQRGEQTYAQLETSE 544

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 861483604   712 KITKGSLEEEKCRAAAALEEHQHHISEMEA------------------------ESRSLAEQHKQERKELEEEKAKRRGL 767
Cdd:TIGR00618  545 EDVYHQLTSERKQRASLKEQMQEIQQSFSIltqcdnrskedipnlqnitvrlqdLTEKLSEAEDMLACEQHALLRKLQPE 624

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 861483604   768 GVQLQQLAETHQAETKALRQELAKARTSNNMAEREVELLVKEVKTWRKRYEDSQQGETQY--GLQEQLTTLKEEYEKSCQ 845
Cdd:TIGR00618  625 QDLQDVRLHLQQCSQELALKLTALHALQLTLTQERVREHALSIRVLPKELLASRQLALQKmqSEKEQLTYWKEMLAQCQT 704

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 861483604   846 ELRETKEKMAGIEAHSELQIGQHQSELAQLHANLArALQQVQEKENRAQKLADDLSTLQEKmaatSKEVARLEALVRKAG 925
Cdd:TIGR00618  705 LLRELETHIEEYDREFNEIENASSSLGSDLAARED-ALNQSLKELMHQARTVLKARTEAHF----NNNEEVTAALQTGAE 779

                          650       660       670       680       690       700
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 861483604   926 EQQETASLELLKEPPKTRDRESEWVEEQQGQQLCSTQAALRA----MEREAEQMGTELEKLRAALME 988
Cdd:TIGR00618  780 LSHLAAEIQFFNRLREEDTHLLKTLEAEIGQEIPSDEDILNLqcetLVQEEEQFLSRLEEKSATLGE 846
PRK02224 PRK02224
DNA double-strand break repair Rad50 ATPase;
1010-1543 2.80e-08

DNA double-strand break repair Rad50 ATPase;


Pssm-ID: 179385 [Multi-domain]  Cd Length: 880  Bit Score: 59.28  E-value: 2.80e-08
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 861483604 1010 ERGQAEADLALEKAAKAELEMRLQNALNEQQAEFANLQEALSRALSEKEGKDQ---ELSKLCEQEAVQRMELKELLQTVE 1086
Cdd:PRK02224  182 LSDQRGSLDQLKAQIEEKEEKDLHERLNGLESELAELDEEIERYEEQREQAREtrdEADEVLEEHEERREELETLEAEIE 261

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 861483604 1087 QLKAQLAKKEKEQqqsargasgenasgmgtqseavgkmEALRAKVSKLEQQCQQQQEEADSLARSLESERAFHVERDRAL 1166
Cdd:PRK02224  262 DLRETIAETERER-------------------------EELAEEVRDLRERLEELEEERDDLLAEAGLDDADAEAVEARR 316

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 861483604 1167 ETLQGQLEEKARELGYSQAASASAQRELATLRAKAQDHSKAEEEWKAQVARGQQEAVRKGSLISSLEEEVSILNRQVLEK 1246
Cdd:PRK02224  317 EELEDRDEELRDRLEECRVAAQAHNEEAESLREDADDLEERAEELREEAAELESELEEAREAVEDRREEIEELEEEIEEL 396

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 861483604 1247 EgeskelKRLVIAESEKsQKLEERLRLLqmetASNSARAAERSSALREEVQSLREEVEKQRAASENLR------------ 1314
Cdd:PRK02224  397 R------ERFGDAPVDL-GNAEDFLEEL----REERDELREREAELEATLRTARERVEEAEALLEAGKcpecgqpvegsp 465

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 861483604 1315 --QELASQAERAEELGQELKAWQEKFFQKEQALSALQlEHTSTQALVSELLPAKHLCQQLQAEQVAAEKRHREELEQSKQ 1392
Cdd:PRK02224  466 hvETIEEDRERVEELEAELEDLEEEVEEVEERLERAE-DLVEAEDRIERLEERREDLEELIAERRETIEEKRERAEELRE 544

                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 861483604 1393 AAGGLRTEL-----------MRAQRELGELVPLRQKVAEQERAAQQLR------AEKASYAEQLSMLKKAHGLLAEENR- 1454
Cdd:PRK02224  545 RAAELEAEAeekreaaaeaeEEAEEAREEVAELNSKLAELKERIESLErirtllAAIADAEDEIERLREKREALAELNDe 624

                         490       500       510       520       530       540       550       560
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 861483604 1455 ---GLGERANLGRQfLEVELDQARekyIQELAAVRGDAETRLAEMRQEVQSTTHELEVMTAKYEGAKVKvLEERQRFQEE 1531
Cdd:PRK02224  625 rreRLAEKRERKRE-LEAEFDEAR---IEEAREDKERAEEYLEQVEEKLDELREERDDLQAEIGAVENE-LEELEELRER 699

                         570
                  ....*....|..
gi 861483604 1532 RQKLTAQVEQLE 1543
Cdd:PRK02224  700 REALENRVEALE 711
PRK02224 PRK02224
DNA double-strand break repair Rad50 ATPase;
786-1337 3.05e-08

DNA double-strand break repair Rad50 ATPase;


Pssm-ID: 179385 [Multi-domain]  Cd Length: 880  Bit Score: 59.28  E-value: 3.05e-08
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 861483604  786 RQELAKARTSNNMAEREVELLVKEVKTWRKRYEDSQQGETQYGLQEQLTTLKEE---YEKSCQELRETKEKMAG-IEAHS 861
Cdd:PRK02224  168 RERASDARLGVERVLSDQRGSLDQLKAQIEEKEEKDLHERLNGLESELAELDEEierYEEQREQARETRDEADEvLEEHE 247

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 861483604  862 ElqigqHQSELAQLHANLARALQQVQEKENRAQKLADDLSTLQEkmAATSKEVARLEALVRKAGEQQETASLELLKEPPK 941
Cdd:PRK02224  248 E-----RREELETLEAEIEDLRETIAETEREREELAEEVRDLRE--RLEELEEERDDLLAEAGLDDADAEAVEARREELE 320

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 861483604  942 TRDRESEWVEEQQGQQLCSTQAALRAMEREAEQMGTELEKLRaalmesqgqqqeergqqeREVARLTQERGQAEADLALE 1021
Cdd:PRK02224  321 DRDEELRDRLEECRVAAQAHNEEAESLREDADDLEERAEELR------------------EEAAELESELEEAREAVEDR 382

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 861483604 1022 KAAKAELEMRLQnalnEQQAEFANLQEALSRALSEKEGKDQELSKLCEQEAVQRMELKELLQTVEQLKAQL-AKKEKEQQ 1100
Cdd:PRK02224  383 REEIEELEEEIE----ELRERFGDAPVDLGNAEDFLEELREERDELREREAELEATLRTARERVEEAEALLeAGKCPECG 458

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 861483604 1101 QSARGAsgENASGMGTQSEAVGKMEALRAKVSKLEQQCQQQQEEADSLArslESERAFHVERDRAlETLQGQLEEKarel 1180
Cdd:PRK02224  459 QPVEGS--PHVETIEEDRERVEELEAELEDLEEEVEEVEERLERAEDLV---EAEDRIERLEERR-EDLEELIAER---- 528

                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 861483604 1181 gysqAASASAQRE-LATLRAKAQDHSKAEEEWKAQVARGQQEAVRKGSLISSLEEEvsilnRQVLEKEGESKELKRLVIA 1259
Cdd:PRK02224  529 ----RETIEEKRErAEELRERAAELEAEAEEKREAAAEAEEEAEEAREEVAELNSK-----LAELKERIESLERIRTLLA 599

                         490       500       510       520       530       540       550
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 861483604 1260 ESEKSQKLEERLRLLQMETASNSARAAERSSALREEVQSLREEVEKQRAasENLRQELASQAERAEELGQELKAWQEK 1337
Cdd:PRK02224  600 AIADAEDEIERLREKREALAELNDERRERLAEKRERKRELEAEFDEARI--EEAREDKERAEEYLEQVEEKLDELREE 675
PRK03918 PRK03918
DNA double-strand break repair ATPase Rad50;
205-831 3.52e-08

DNA double-strand break repair ATPase Rad50;


Pssm-ID: 235175 [Multi-domain]  Cd Length: 880  Bit Score: 58.92  E-value: 3.52e-08
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 861483604  205 MGDILQTPQFQMRRLKKQLADERNNRDELElelaEHRKLLTEKDAQISMMQQRIDRLAllnEKQAASPLEPRELEELRGK 284
Cdd:PRK03918  167 LGEVIKEIKRRIERLEKFIKRTENIEELIK----EKEKELEEVLREINEISSELPELR---EELEKLEKEVKELEELKEE 239

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 861483604  285 NESLTFRLHETLKQCQDLKTEKGQMDRKINQLSEENGDLSFKLREfasnLQQLQGaLNELTEEHSKATQQWVEKQAHLEK 364
Cdd:PRK03918  240 IEELEKELESLEGSKRKLEEKIRELEERIEELKKEIEELEEKVKE----LKELKE-KAEEYIKLSEFYEEYLDELREIEK 314

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 861483604  365 ELSTALQDKKCLEEKNEILQGKLSQLEErLAQLPESPRQEKGEVLGDVLQLESLKQeaatLATNNTQLQARVEMLENEQG 444
Cdd:PRK03918  315 RLSRLEEEINGIEERIKELEEKEERLEE-LKKKLKELEKRLEELEERHELYEEAKA----KKEELERLKKRLTGLTPEKL 389

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 861483604  445 QKEAQLLGER-SHFEEEKQQLASLITNLQSSISNLSQAKEELEQASQ---AQGAKLNAQ-----VASLTAELTTLSATLQ 515
Cdd:PRK03918  390 EKELEELEKAkEEIEEEISKITARIGELKKEIKELKKAIEELKKAKGkcpVCGRELTEEhrkelLEEYTAELKRIEKELK 469

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 861483604  516 QQDQELaglkqqaqkkqaqlaqslqqqeqasqglrhqvEQLSGSLKQKEKQLEEaARELDASRRDHAQQLATAAKAQETS 595
Cdd:PRK03918  470 EIEEKE--------------------------------RKLRKELRELEKVLKK-ESELIKLKELAEQLKELEEKLKKYN 516

                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 861483604  596 LRERDAACQQLEALeKEKAAKLEILQQQLQAANEAQDSAQNSVTQAQREKAELSQKVEELHALIEAAHQEQCEaqtQVAA 675
Cdd:PRK03918  517 LEELEKKAEEYEKL-KEKLIKLKGEIKSLKKELEKLEELKKKLAELEKKLDELEEELAELLKELEELGFESVE---ELEE 592

                         490       500       510       520       530       540       550       560
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 861483604  676 LEARLKAEQQKATEREKVAQEKAQLQEQLWSLEESLKITKGSLEEEKcraaAALEEHQHHISEMeaESRSLAEQHKQERK 755
Cdd:PRK03918  593 RLKELEPFYNEYLELKDAEKELEREEKELKKLEEELDKAFEELAETE----KRLEELRKELEEL--EKKYSEEEYEELRE 666

                         570       580       590       600       610       620       630
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 861483604  756 ELEEEKAKRRGLGVQLQQLaETHQAETKALRQELAKARTSNNMAEREVELLVK---EVKTWRKRYEDSQQGETQYGLQE 831
Cdd:PRK03918  667 EYLELSRELAGLRAELEEL-EKRREEIKKTLEKLKEELEEREKAKKELEKLEKaleRVEELREKVKKYKALLKERALSK 744
PRK02224 PRK02224
DNA double-strand break repair Rad50 ATPase;
567-985 3.90e-08

DNA double-strand break repair Rad50 ATPase;


Pssm-ID: 179385 [Multi-domain]  Cd Length: 880  Bit Score: 58.90  E-value: 3.90e-08
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 861483604  567 LEEAARELDASRRDHAQQLATAAKAQETSLRERDAACQQLEALEKEKAAKLEILQQQ---LQAANEAQDSAQNSVTQAQR 643
Cdd:PRK02224  277 LAEEVRDLRERLEELEEERDDLLAEAGLDDADAEAVEARREELEDRDEELRDRLEECrvaAQAHNEEAESLREDADDLEE 356

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 861483604  644 EKAELSQKVEELHALIEAAHQEQCEAQTQVAALEARLKAEQQK----ATEREKVAQEKAQLQEQLWSLEESLKITKGSLE 719
Cdd:PRK02224  357 RAEELREEAAELESELEEAREAVEDRREEIEELEEEIEELRERfgdaPVDLGNAEDFLEELREERDELREREAELEATLR 436

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 861483604  720 EEKCR---AAAALEEHQHHISEMEAESRSLAEQHKQERKELEEEKAKRRGLGVQLQQLAETHQAETKALRqelakartsn 796
Cdd:PRK02224  437 TARERveeAEALLEAGKCPECGQPVEGSPHVETIEEDRERVEELEAELEDLEEEVEEVEERLERAEDLVE---------- 506

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 861483604  797 nmAEREVELLVKEVKTWRKRYEDsqQGETQYGLQEQLTTLKEEYEKSCQELRETKEKMAgiEAHSELQigqhqsELAQLH 876
Cdd:PRK02224  507 --AEDRIERLEERREDLEELIAE--RRETIEEKRERAEELRERAAELEAEAEEKREAAA--EAEEEAE------EAREEV 574

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 861483604  877 ANLARALQQVQEKENRAQKLADDLSTLQEKMAATSKEVARLEALVRKAGEQQETaslelLKEppkTRDRESEWVEEQQGQ 956
Cdd:PRK02224  575 AELNSKLAELKERIESLERIRTLLAAIADAEDEIERLREKREALAELNDERRER-----LAE---KRERKRELEAEFDEA 646

                         410       420
                  ....*....|....*....|....*....
gi 861483604  957 QLCSTQAALRAMEREAEQMGTELEKLRAA 985
Cdd:PRK02224  647 RIEEAREDKERAEEYLEQVEEKLDELREE 675
YhaN COG4717
Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown];
431-926 5.34e-08

Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown];


Pssm-ID: 443752 [Multi-domain]  Cd Length: 641  Bit Score: 58.24  E-value: 5.34e-08
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 861483604  431 QLQARVEMLENEQGQKEAQLLGERSHFEEEKQQLASLITNLQSSISNLSQAKEELEQAsQAQGAKLNAQVASLTA--ELT 508
Cdd:COG4717    50 RLEKEADELFKPQGRKPELNLKELKELEEELKEAEEKEEEYAELQEELEELEEELEEL-EAELEELREELEKLEKllQLL 128

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 861483604  509 TLSATLQQQDQELAGLKQQAQKKQAQLAQSLQqqeqasqgLRHQVEQLSGSLKQKEKQLEEAARELDASRRDHAQQLATA 588
Cdd:COG4717   129 PLYQELEALEAELAELPERLEELEERLEELRE--------LEEELEELEAELAELQEELEELLEQLSLATEEELQDLAEE 200

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 861483604  589 AKAQETSLRERDAACQQLEALEKEKAAKLEILQQQLQAANEAQDSAQNSVTQ----AQREKAELSQKVEELHALIEAAHQ 664
Cdd:COG4717   201 LEELQQRLAELEEELEEAQEELEELEEELEQLENELEAAALEERLKEARLLLliaaALLALLGLGGSLLSLILTIAGVLF 280

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 861483604  665 EQCEAQTQVAALEARLKAEQQKATEREKVAQEKAQLQEQLWsleESLKITKGSLEEEKCRAAAALEEHQHHISEMEAESR 744
Cdd:COG4717   281 LVLGLLALLFLLLAREKASLGKEAEELQALPALEELEEEEL---EELLAALGLPPDLSPEELLELLDRIEELQELLREAE 357

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 861483604  745 SLAEQHKQERKELEeekakrrglgvqLQQLAETHQAETKALRQELAKARTSNNMAEREVELLVKEVKTWRKRYEDSQQGE 824
Cdd:COG4717   358 ELEEELQLEELEQE------------IAALLAEAGVEDEEELRAALEQAEEYQELKEELEELEEQLEELLGELEELLEAL 425

                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 861483604  825 TQYGLQEQLTTLKEEYEKSCQELRETKEKMAGIEAhsELQIGQHQSELAQLHANLARALQQVQEKENRAQKLADDLSTLQ 904
Cdd:COG4717   426 DEEELEEELEELEEELEELEEELEELREELAELEA--ELEQLEEDGELAELLQELEELKAELRELAEEWAALKLALELLE 503

                         490       500
                  ....*....|....*....|..
gi 861483604  905 EKMAATSKEvaRLEALVRKAGE 926
Cdd:COG4717   504 EAREEYREE--RLPPVLERASE 523
COG4913 COG4913
Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];
1182-1664 6.07e-08

Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];


Pssm-ID: 443941 [Multi-domain]  Cd Length: 1089  Bit Score: 58.39  E-value: 6.07e-08
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 861483604 1182 YSQAASASAQRE-LATLRAKAQDHSKAEEEwkaqvaRGQQEAVRKGSLISSLEEEVSILNRQVLEKEGESKELKRLVIAE 1260
Cdd:COG4913   241 HEALEDAREQIElLEPIRELAERYAAARER------LAELEYLRAALRLWFAQRRLELLEAELEELRAELARLEAELERL 314

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 861483604 1261 SEKSQKLEERLRLLQMETASNSARAAERssaLREEVQSLREEVEKQRAASENLRQELASQ------------------AE 1322
Cdd:COG4913   315 EARLDALREELDELEAQIRGNGGDRLEQ---LEREIERLERELEERERRRARLEALLAALglplpasaeefaalraeaAA 391

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 861483604 1323 RAEELGQELKAWQEKFFQKEQALSALQLEHTSTQALVSEL------LPA------KHLCQQLQAEQVAA----------- 1379
Cdd:COG4913   392 LLEALEEELEALEEALAEAEAALRDLRRELRELEAEIASLerrksnIPArllalrDALAEALGLDEAELpfvgelievrp 471

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 861483604 1380 -EKRHREELEqskQAAGGLRTELMRAQRELGEL------VPLR-----QKVAEQERAAQQLRAEKASYAEQLSMlkKAHG 1447
Cdd:COG4913   472 eEERWRGAIE---RVLGGFALTLLVPPEHYAAAlrwvnrLHLRgrlvyERVRTGLPDPERPRLDPDSLAGKLDF--KPHP 546

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 861483604 1448 LLAEENRGLGERANLGRQFLEVELDQAR--------------------EKYIQELAAVRGDAETRLAEMRQEVQSTTHEL 1507
Cdd:COG4913   547 FRAWLEAELGRRFDYVCVDSPEELRRHPraitragqvkgngtrhekddRRRIRSRYVLGFDNRAKLAALEAELAELEEEL 626

                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 861483604 1508 EVMTAKYEGAKVKVLEERQRFQEERQKLTAQVEQLEVfqREQTKKVEELSKKLADYDQAS----------KVQQQKLKAF 1577
Cdd:COG4913   627 AEAEERLEALEAELDALQERREALQRLAEYSWDEIDV--ASAEREIAELEAELERLDASSddlaaleeqlEELEAELEEL 704

                         490       500       510       520       530       540       550       560
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 861483604 1578 QAQGGESQQEAQRLQTQLNELQVQLSQKEQAAEHY-KVQMEKAKTHYDAKKQQNQELQEQLQGLEQLQKENKELRAEAER 1656
Cdd:COG4913   705 EEELDELKGEIGRLEKELEQAEEELDELQDRLEAAeDLARLELRALLEERFAAALGDAVERELRENLEERIDALRARLNR 784


                  ....*...
gi 861483604 1657 LGQELQQA 1664
Cdd:COG4913   785 AEEELERA 792
COG4913 COG4913
Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];
326-795 6.33e-08

Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];


Pssm-ID: 443941 [Multi-domain]  Cd Length: 1089  Bit Score: 58.00  E-value: 6.33e-08
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 861483604  326 KLREFASNLQQLQGALNELTEEHSKATQQWVE-KQAHLE---KELSTALQDKKCLEEKNEILQGKLSQLEERLAQLPESP 401
Cdd:COG4913   296 ELEELRAELARLEAELERLEARLDALREELDElEAQIRGnggDRLEQLEREIERLERELEERERRRARLEALLAALGLPL 375

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 861483604  402 RQEKGEvlgdvlqLESLKQEAATLATNNTQLQARVEmleneqgQKEAQLLGERSHFEEEKQQLASLITNLQSSISNLS-- 479
Cdd:COG4913   376 PASAEE-------FAALRAEAAALLEALEEELEALE-------EALAEAEAALRDLRRELRELEAEIASLERRKSNIPar 441

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 861483604  480 --QAKEELEQASQAQGAKLNA-----QVASLTAE--------LTTLSATL---QQQDQELAGLKQQAQKKQAQLAQSLQQ 541
Cdd:COG4913   442 llALRDALAEALGLDEAELPFvgeliEVRPEEERwrgaiervLGGFALTLlvpPEHYAAALRWVNRLHLRGRLVYERVRT 521

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 861483604  542 QEQASQGLRHQVEQLSGSLKQKEKQLEEAARELDASRRDHA-----QQLATAAKA--------QETSLRERDAACQQLEA 608
Cdd:COG4913   522 GLPDPERPRLDPDSLAGKLDFKPHPFRAWLEAELGRRFDYVcvdspEELRRHPRAitragqvkGNGTRHEKDDRRRIRSR 601

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 861483604  609 --LEKEKAAKLEILQQQLQAANEAQDSAQNSVTQAQREKAELSQKVEELHALIEAAHQEQ--CEAQTQVAALEARLKAEQ 684
Cdd:COG4913   602 yvLGFDNRAKLAALEAELAELEEELAEAEERLEALEAELDALQERREALQRLAEYSWDEIdvASAEREIAELEAELERLD 681

                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 861483604  685 QKATEREKVAQEKAQLQEQLWSLEE---SLKITKGSLEEEKCRAAAALEEHQHHISEMEAESRSLAEQHKQERKELEEEK 761
Cdd:COG4913   682 ASSDDLAALEEQLEELEAELEELEEeldELKGEIGRLEKELEQAEEELDELQDRLEAAEDLARLELRALLEERFAAALGD 761

                         490       500       510
                  ....*....|....*....|....*....|....
gi 861483604  762 AKRRGLGVQLQQLAETHQAETKALRQELAKARTS 795
Cdd:COG4913   762 AVERELRENLEERIDALRARLNRAEEELERAMRA 795
PRK02224 PRK02224
DNA double-strand break repair Rad50 ATPase;
1293-1689 6.81e-08

DNA double-strand break repair Rad50 ATPase;


Pssm-ID: 179385 [Multi-domain]  Cd Length: 880  Bit Score: 58.13  E-value: 6.81e-08
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 861483604 1293 REEVQSLREEVEKQRAA-------SENLRQELASQAERAEELGQELkawqekffqkEQALSALQLEHTSTQALvsellpa 1365
Cdd:PRK02224  250 REELETLEAEIEDLRETiaetereREELAEEVRDLRERLEELEEER----------DDLLAEAGLDDADAEAV------- 312

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 861483604 1366 khlcQQLQAEQVAAEKRHREELEQSKQAAGGLRTElmrAQRELGELVPLRQKVAEQERAAQQLRAEKASYAEQLSMLKKA 1445
Cdd:PRK02224  313 ----EARREELEDRDEELRDRLEECRVAAQAHNEE---AESLREDADDLEERAEELREEAAELESELEEAREAVEDRREE 385

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 861483604 1446 HGLLAEENRGLGERANlgrqFLEVELDQArEKYIQELAAVRGDAETRLAEMRQEVQSTTHELEVMTAKYEGAK------- 1518
Cdd:PRK02224  386 IEELEEEIEELRERFG----DAPVDLGNA-EDFLEELREERDELREREAELEATLRTARERVEEAEALLEAGKcpecgqp 460

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 861483604 1519 ------VKVLEERQrfqEERQKLTAQVEQLEVFQREQTKKVEELSKKLADYDQASKVQQQ-----KLKAFQAQGGESQQE 1587
Cdd:PRK02224  461 vegsphVETIEEDR---ERVEELEAELEDLEEEVEEVEERLERAEDLVEAEDRIERLEERredleELIAERRETIEEKRE 537

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 861483604 1588 -AQRLQTQLNELQVQLSQKEQAAEHYKVQMEKAKTH---YDAKKQQNQELQEQLQGLEQLQKENKELRAEAERLGQELQQ 1663
Cdd:PRK02224  538 rAEELRERAAELEAEAEEKREAAAEAEEEAEEAREEvaeLNSKLAELKERIESLERIRTLLAAIADAEDEIERLREKREA 617

                         410       420
                  ....*....|....*....|....*.
gi 861483604 1664 AGLKTKEAEQTCRHLTAQVRSLEAQV 1689
Cdd:PRK02224  618 LAELNDERRERLAEKRERKRELEAEF 643
MukB COG3096
Chromosome condensin MukBEF, ATPase and DNA-binding subunit MukB [Cell cycle control, cell ...
 227-1042 7.77e-08

Chromosome condensin MukBEF, ATPase and DNA-binding subunit MukB [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 442330 [Multi-domain]  Cd Length: 1470  Bit Score: 58.04  E-value: 7.77e-08
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 861483604  227 RNNRDELELELAEHRKLLTEKDAQISMMQQRIDRLAllnekqaasplepRELEELRGKNESLTFRLHETLKQCQDLKTEK 306
Cdd:COG3096   277 ANERRELSERALELRRELFGARRQLAEEQYRLVEMA-------------RELEELSARESDLEQDYQAASDHLNLVQTAL 343

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 861483604  307 GQMDrKINQLSEENGDLSFKLREfasnlqqLQGALNELTEEHSKATQQWVEKQAHLeKELSTALQDkkcLEEKNEILQGK 386
Cdd:COG3096   344 RQQE-KIERYQEDLEELTERLEE-------QEEVVEEAAEQLAEAEARLEAAEEEV-DSLKSQLAD---YQQALDVQQTR 411

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 861483604  387 LSQLEERLAQLpesprqEKGEVLgdvLQLESLKQEAA--TLATNNTQLQARVE-MLENEQGQKEAQllGERSHFEEEKQQ 463
Cdd:COG3096   412 AIQYQQAVQAL------EKARAL---CGLPDLTPENAedYLAAFRAKEQQATEeVLELEQKLSVAD--AARRQFEKAYEL 480

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 861483604  464 LASLITNLQSSISNlSQAKEELEQASQAQgaKLNAQVASLTAELTTLSATLQQQDQelaglkqqaqkkqaqlaqslqqqe 543
Cdd:COG3096   481 VCKIAGEVERSQAW-QTARELLRRYRSQQ--ALAQRLQQLRAQLAELEQRLRQQQN------------------------ 533

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 861483604  544 qasqgLRHQVEQLSGSLKQK---EKQLEEAARELDASRRDHAQQLATAAKAQETSLRERDAACQQLEALEK------EKA 614
Cdd:COG3096   534 -----AERLLEEFCQRIGQQldaAEELEELLAELEAQLEELEEQAAEAVEQRSELRQQLEQLRARIKELAArapawlAAQ 608

                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 861483604  615 AKLEILQQQ----LQAANEAQDSAQNSV---TQAQREKAELSQKVEELHALIEAAHQEQCEAQTQVAALEARLKAEQ--- 684
Cdd:COG3096   609 DALERLREQsgeaLADSQEVTAAMQQLLereREATVERDELAARKQALESQIERLSQPGGAEDPRLLALAERLGGVLlse 688

                         490       500       510       520       530       540       550       560
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 861483604  685 -------QKATEREK---------VAQEKAQLQEQLWSLE---ESLKITKG----------SLEEEKCRAAAALEEHQHH 735
Cdd:COG3096   689 iyddvtlEDAPYFSAlygparhaiVVPDLSAVKEQLAGLEdcpEDLYLIEGdpdsfddsvfDAEELEDAVVVKLSDRQWR 768

                         570       580       590       600       610       620       630       640
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 861483604  736 ISEMEA---------ESRslAEQHKQERKELEEEKAKRRglgVQLQQLAETHQAETKALRQ------------ELAKART 794
Cdd:COG3096   769 YSRFPEvplfgraarEKR--LEELRAERDELAEQYAKAS---FDVQKLQRLHQAFSQFVGGhlavafapdpeaELAALRQ 843

                         650       660       670       680       690       700       710       720
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 861483604  795 SNNMAEREVELLVKEVKTWRKRYEDSQQGETQY-GLQEQLTTLKEE-YEKSCQELREtkEKMAGIEAHSELQigQHQSEL 872
Cdd:COG3096   844 RRSELERELAQHRAQEQQLRQQLDQLKEQLQLLnKLLPQANLLADEtLADRLEELRE--ELDAAQEAQAFIQ--QHGKAL 919

                         730       740       750       760       770       780       790       800
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 861483604  873 AQLhANLARALQ----QVQEKENRAQKLADDLSTLQEKMAATSKEVARLEALVRKAGEQQETASLEL-------LKEPPK 941
Cdd:COG3096   920 AQL-EPLVAVLQsdpeQFEQLQADYLQAKEQQRRLKQQIFALSEVVQRRPHFSYEDAVGLLGENSDLneklrarLEQAEE 998

                         810       820       830       840       850       860       870       880
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 861483604  942 TRDRESEWVEEQQGQ--QLCSTQAALRAMEREAEQMGTELEKLRAAL-----MESQGQQQEERGQQEREVARLTQERGQA 1014
Cdd:COG3096   999 ARREAREQLRQAQAQysQYNQVLASLKSSRDAKQQTLQELEQELEELgvqadAEAEERARIRRDELHEELSQNRSRRSQL 1078

                         890       900
                  ....*....|....*....|....*...
gi 861483604 1015 EADLALEKAAKAELEMRLQNALNEQQAE 1042
Cdd:COG3096  1079 EKQLTRCEAEMDSLQKRLRKAERDYKQE 1106
COG4913 COG4913
Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];
460-985 1.17e-07

Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];


Pssm-ID: 443941 [Multi-domain]  Cd Length: 1089  Bit Score: 57.23  E-value: 1.17e-07
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 861483604  460 EKQQLASLITNLQSSISNLSQAKEELEQAsQAQGAKLnAQVASLTAELTTLSATLQQQDQELAGlkqqaqkkqaqlaqsl 539
Cdd:COG4913   219 EEPDTFEAADALVEHFDDLERAHEALEDA-REQIELL-EPIRELAERYAAARERLAELEYLRAA---------------- 280

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 861483604  540 qqqeqasqgLRHQVEQLS-GSLKQKEKQLEEAARELDASRRDHAQQLaTAAKAQETSLRE--RDAACQQLEALEKEKAAK 616
Cdd:COG4913   281 ---------LRLWFAQRRlELLEAELEELRAELARLEAELERLEARL-DALREELDELEAqiRGNGGDRLEQLEREIERL 350

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 861483604  617 LEILQQQLQAANEAQDSAQNSVTQAQREKAELSQKVEELHALIEAAHQEQCEAQTQVAALEARLKAEQQkatEREKVAQE 696
Cdd:COG4913   351 ERELEERERRRARLEALLAALGLPLPASAEEFAALRAEAAALLEALEEELEALEEALAEAEAALRDLRR---ELRELEAE 427

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 861483604  697 KAQLQEQLWS-----------LEESLKITKGSL-----------EEEKCRAAA--------------------------- 727
Cdd:COG4913   428 IASLERRKSNiparllalrdaLAEALGLDEAELpfvgelievrpEEERWRGAIervlggfaltllvppehyaaalrwvnr 507

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 861483604  728 ----------ALEEHQHHISEMEAESRSLAEQ---------------------------------------------HKQ 752
Cdd:COG4913   508 lhlrgrlvyeRVRTGLPDPERPRLDPDSLAGKldfkphpfrawleaelgrrfdyvcvdspeelrrhpraitragqvkGNG 587

                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 861483604  753 ERKELEEEKAKRRG--LGVQLQQLAETHQAETKALRQELAKARTSNNMAEREVELLVKEVKTWRKRYEDSQQGETQYGLQ 830
Cdd:COG4913   588 TRHEKDDRRRIRSRyvLGFDNRAKLAALEAELAELEEELAEAEERLEALEAELDALQERREALQRLAEYSWDEIDVASAE 667

                         490       500       510       520       530       540       550       560
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 861483604  831 EQLTTLKEEYEkscqELRETkekmagieahselqigqhQSELAQLHANLARALQQVQEKENRAQKLADDLSTLQEKMAAT 910
Cdd:COG4913   668 REIAELEAELE----RLDAS------------------SDDLAALEEQLEELEAELEELEEELDELKGEIGRLEKELEQA 725

                         570       580       590       600       610       620       630
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 861483604  911 SKEVARLEALVRKAGEQQETASLELLKEppktrDRESEWVEEQQGQQLCSTQAALRAMEREAEQMGTELEKLRAA 985
Cdd:COG4913   726 EEELDELQDRLEAAEDLARLELRALLEE-----RFAAALGDAVERELRENLEERIDALRARLNRAEEELERAMRA 795
DUF3584 pfam12128
Protein of unknown function (DUF3584); This protein is found in bacteria and eukaryotes. ...
 1161-1720 1.30e-07

Protein of unknown function (DUF3584); This protein is found in bacteria and eukaryotes. Proteins in this family are typically between 943 to 1234 amino acids in length. This family contains a P-loop motif suggesting it is a nucleotide binding protein. It may be involved in replication.


Pssm-ID: 432349 [Multi-domain]  Cd Length: 1191  Bit Score: 57.16  E-value: 1.30e-07
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 861483604  1161 ERDRALETLQGQLEEKARELGYSQAASASAQRELATLRA-KAQDHSKAEEEWKAQVARGQQEAVRKGSLISSLEEEVSIL 1239
Cdd:pfam12128  248 QEFNTLESAELRLSHLHFGYKSDETLIASRQEERQETSAeLNQLLRTLDDQWKEKRDELNGELSAADAAVAKDRSELEAL 327

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 861483604  1240 NRQVLEKEGESKE-----LKRLVIAESEKSQkLEERLRLL----QMETASNSARAAERSSALREEVQSL-------REEV 1303
Cdd:pfam12128  328 EDQHGAFLDADIEtaaadQEQLPSWQSELEN-LEERLKALtgkhQDVTAKYNRRRSKIKEQNNRDIAGIkdklakiREAR 406

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 861483604  1304 EKQRAASENLRQELASQAEraEELGQELKAWQEKFFQKEQALSALQLEHTSTQALVSELLpakhlcqQLQAEQVAAEkRH 1383
Cdd:pfam12128  407 DRQLAVAEDDLQALESELR--EQLEAGKLEFNEEEYRLKSRLGELKLRLNQATATPELLL-------QLENFDERIE-RA 476

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 861483604  1384 REELEQSkqaagglRTELMRAQRELGELVPLRQKVAEQ----ERAAQQLRAEKASYAEQLSmlKKAHGLLA--------- 1450
Cdd:pfam12128  477 REEQEAA-------NAEVERLQSELRQARKRRDQASEAlrqaSRRLEERQSALDELELQLF--PQAGTLLHflrkeapdw 547

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 861483604  1451 EENRG-LGERANLGRQFLEVELDQAREKYIQELAAVRGDAEtrlaemRQEVQSTTHELEVMTAKYEGAKVKVLEERQRFQ 1529
Cdd:pfam12128  548 EQSIGkVISPELLHRTDLDPEVWDGSVGGELNLYGVKLDLK------RIDVPEWAASEEELRERLDKAEEALQSAREKQA 621

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 861483604  1530 EERQKLTAQVEQLEVFQREQTKKVEELSKKLADYDQASKVQQQ-KLKAFQAQGGESQQEAQRLQTQLNELQVQLSQKEQA 1608
Cdd:pfam12128  622 AAEEQLVQANGELEKASREETFARTALKNARLDLRRLFDEKQSeKDKKNKALAERKDSANERLNSLEAQLKQLDKKHQAW 701

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 861483604  1609 AEHYKVQMEKAKTHYDAKKQQNQELQEQLQGL--EQLQKENKELRAEAERLGQELQQAGLKTKEAEQTCRHLTAQVRSLE 1686
Cdd:pfam12128  702 LEEQKEQKREARTEKQAYWQVVEGALDAQLALlkAAIAARRSGAKAELKALETWYKRDLASLGVDPDVIAKLKREIRTLE 781

                          570       580       590
                   ....*....|....*....|....*....|....
gi 861483604  1687 AQVAHADQQLRELGKFQvasDALKSREPQAKPQL 1720
Cdd:pfam12128  782 RKIERIAVRRQEVLRYF---DWYQETWLQRRPRL 812
COG4913 COG4913
Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];
1163-1601 1.42e-07

Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];


Pssm-ID: 443941 [Multi-domain]  Cd Length: 1089  Bit Score: 56.85  E-value: 1.42e-07
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 861483604 1163 DRALETLQGQLEEKARELGYSQAASASAQRELATLRAKAQDHS-KAEEEWKAQVARGQQEAVRKGSLISSLEEEVSILNR 1241
Cdd:COG4913   294 EAELEELRAELARLEAELERLEARLDALREELDELEAQIRGNGgDRLEQLEREIERLERELEERERRRARLEALLAALGL 373

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 861483604 1242 QVLEKEGESKELKRLVIAESEKSQKLEERLRLLQMETASNSARAAERSSALREEVQSLREEVEKQRAASENLRQELASQA 1321
Cdd:COG4913   374 PLPASAEEFAALRAEAAALLEALEEELEALEEALAEAEAALRDLRRELRELEAEIASLERRKSNIPARLLALRDALAEAL 453

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 861483604 1322 ERAE----------ELGQELKAWQ-----------------EKFFQK-------------------EQALSALQLEHTST 1355
Cdd:COG4913   454 GLDEaelpfvgeliEVRPEEERWRgaiervlggfaltllvpPEHYAAalrwvnrlhlrgrlvyervRTGLPDPERPRLDP 533

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 861483604 1356 QALVSELLPAKHLCQQLQAEQVAAEKRHR-----EELEQSKQAAggLRTELMRAQRELGEL--------VPL-----RQK 1417
Cdd:COG4913   534 DSLAGKLDFKPHPFRAWLEAELGRRFDYVcvdspEELRRHPRAI--TRAGQVKGNGTRHEKddrrrirsRYVlgfdnRAK 611

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 861483604 1418 VAEQERAAQQLRAEKASYAEQLSMLKKAHGLLAEENRGLGERANLgrQFLEVELDQAREKyIQELAAVRGDAET---RLA 1494
Cdd:COG4913   612 LAALEAELAELEEELAEAEERLEALEAELDALQERREALQRLAEY--SWDEIDVASAERE-IAELEAELERLDAssdDLA 688

                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 861483604 1495 EMRQEVQSTTHELEVMTAKYEGAKVK---VLEERQRFQEERQKLTAQVEQLEVFQREQTkkVEELSKKLADYDQAsKVQQ 1571
Cdd:COG4913   689 ALEEQLEELEAELEELEEELDELKGEigrLEKELEQAEEELDELQDRLEAAEDLARLEL--RALLEERFAAALGD-AVER 765

                         490       500       510
                  ....*....|....*....|....*....|
gi 861483604 1572 QKLKAFQAQGGESQQEAQRLQTQLNELQVQ 1601
Cdd:COG4913   766 ELRENLEERIDALRARLNRAEEELERAMRA 795
CCDC158 pfam15921
Coiled-coil domain-containing protein 158; CCDC158 is a family of proteins found in eukaryotes. ...
 242-858 1.56e-07

Coiled-coil domain-containing protein 158; CCDC158 is a family of proteins found in eukaryotes. The function is not known.


Pssm-ID: 464943 [Multi-domain]  Cd Length: 1112  Bit Score: 57.05  E-value: 1.56e-07
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 861483604   242 KLLTEKDAQISMMQQRIdrlallnekqaaSPLEPrELEELRGKNESltfRLHETLKQCQDlktekgQMDRKINQLSEENG 321
Cdd:pfam15921  224 KILRELDTEISYLKGRI------------FPVED-QLEALKSESQN---KIELLLQQHQD------RIEQLISEHEVEIT 281

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 861483604   322 DLSFKLREFASNLQQLQGALNELTEEHSKATQQWVEKQAHLEkelSTALQDKKCLEEKNEILQGKLSQLEERLAQLPESP 401
Cdd:pfam15921  282 GLTEKASSARSQANSIQSQLEIIQEQARNQNSMYMRQLSDLE---STVSQLRSELREAKRMYEDKIEELEKQLVLANSEL 358

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 861483604   402 RQEKGEvlgdvlqLESLKQEAATLATNNTQLQARVEMLENEQGQKEAQ-----------------LLGERSHFEEEKQQL 464
Cdd:pfam15921  359 TEARTE-------RDQFSQESGNLDDQLQKLLADLHKREKELSLEKEQnkrlwdrdtgnsitidhLRRELDDRNMEVQRL 431

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 861483604   465 ASLITNLQSSisnlSQAKEELEQASQAQGAKLNAQVASLTAELTTLSATLQQQDQELAGLKQQAQKKQAQlaqslqqqeq 544
Cdd:pfam15921  432 EALLKAMKSE----CQGQMERQMAAIQGKNESLEKVSSLTAQLESTKEMLRKVVEELTAKKMTLESSERT---------- 497

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 861483604   545 asqglrhqVEQLSGSLKQKEKQLEEAARELDA--SRRDHAQQLATAAKAQETSLRERDAACQQLEALEKEKAAKLEILQQ 622
Cdd:pfam15921  498 --------VSDLTASLQEKERAIEATNAEITKlrSRVDLKLQELQHLKNEGDHLRNVQTECEALKLQMAEKDKVIEILRQ 569

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 861483604   623 QLQAANEAQDSAQNSVTQAQREKAELSQKV-------EELHALIEAAHQEQCEAQTQVAALE-----------ARLKAEQ 684
Cdd:pfam15921  570 QIENMTQLVGQHGRTAGAMQVEKAQLEKEIndrrlelQEFKILKDKKDAKIRELEARVSDLElekvklvnagsERLRAVK 649

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 861483604   685 QKATEREKVAQEKAQLQEQLWSLEESLKITKGSLEEEKcraaaaleehqhhiSEMEAESRSLAEQHKQERKELEEEKAKR 764
Cdd:pfam15921  650 DIKQERDQLLNEVKTSRNELNSLSEDYEVLKRNFRNKS--------------EEMETTTNKLKMQLKSAQSELEQTRNTL 715

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 861483604   765 RGLgvqlqQLAETHQAETK-ALRQELAKARTSNNMAEREVELLVKEVKTWRKryEDSQQGETQYGLQEQLTTLKEEYEKS 843
Cdd:pfam15921  716 KSM-----EGSDGHAMKVAmGMQKQITAKRGQIDALQSKIQFLEEAMTNANK--EKHFLKEEKNKLSQELSTVATEKNKM 788

                          650       660
                   ....*....|....*....|..
gi 861483604   844 CQEL-------RETKEKMAGIE 858
Cdd:pfam15921  789 AGELevlrsqeRRLKEKVANME 810
MukB COG3096
Chromosome condensin MukBEF, ATPase and DNA-binding subunit MukB [Cell cycle control, cell ...
 828-1701 2.30e-07

Chromosome condensin MukBEF, ATPase and DNA-binding subunit MukB [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 442330 [Multi-domain]  Cd Length: 1470  Bit Score: 56.50  E-value: 2.30e-07
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 861483604  828 GLQEQLTTLKEEYEKSCQELRETKEKMagIEAHSEL-QIGQHQSELAQL------HANLARALQQVQEKENRAQklaDDL 900
Cdd:COG3096   282 ELSERALELRRELFGARRQLAEEQYRL--VEMARELeELSARESDLEQDyqaasdHLNLVQTALRQQEKIERYQ---EDL 356

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 861483604  901 STLQEKMAATSKEVARLEALVRKAGEQQETASLELlkeppktrdresewveEQQGQQLCSTQAALRAMEREA---EQMGT 977
Cdd:COG3096   357 EELTERLEEQEEVVEEAAEQLAEAEARLEAAEEEV----------------DSLKSQLADYQQALDVQQTRAiqyQQAVQ 420

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 861483604  978 ELEKLRAALMESQGQQQEERGQQEREVAR---LTQERGQAEADLALEKAAKAELEMRLQnalneqqaefanLQEALSRAL 1054
Cdd:COG3096   421 ALEKARALCGLPDLTPENAEDYLAAFRAKeqqATEEVLELEQKLSVADAARRQFEKAYE------------LVCKIAGEV 488

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 861483604 1055 SEKEGKDQELSKLCEQEavqrmELKELLQTVEQLKAQLAKKEK--EQQQSARGASGENASGMGTQSEAVGKMEALRAkvs 1132
Cdd:COG3096   489 ERSQAWQTARELLRRYR-----SQQALAQRLQQLRAQLAELEQrlRQQQNAERLLEEFCQRIGQQLDAAEELEELLA--- 560

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 861483604 1133 kleqqcqqqqeEADSLARSLESERAFHVERDRALETLQGQLEEKARELgysqAASASAQRELATLRAKAQDHSKAEEEWK 1212
Cdd:COG3096   561 -----------ELEAQLEELEEQAAEAVEQRSELRQQLEQLRARIKEL----AARAPAWLAAQDALERLREQSGEALADS 625

                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 861483604 1213 AQVARGQQEAVRKgslisslEEEVSILNRQVLEKEGE-SKELKRLVI---AESEKSQKLEERL--RLLQM--------ET 1278
Cdd:COG3096   626 QEVTAAMQQLLER-------EREATVERDELAARKQAlESQIERLSQpggAEDPRLLALAERLggVLLSEiyddvtleDA 698

                         490       500       510       520       530       540       550       560
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 861483604 1279 ASNSARAAERSSAL--------REEVQSL-----------------------REEVEKQRAASENLRQ-------EL--- 1317
Cdd:COG3096   699 PYFSALYGPARHAIvvpdlsavKEQLAGLedcpedlyliegdpdsfddsvfdAEELEDAVVVKLSDRQwrysrfpEVplf 778

                         570       580       590       600       610       620       630       640
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 861483604 1318 --ASQAERAEELGQELKAWQEKFFQKEQALSALQLEHTSTQALVsellpAKHLcqqlqaeQVAAEKRHREELEQskqaag 1395
Cdd:COG3096   779 grAAREKRLEELRAERDELAEQYAKASFDVQKLQRLHQAFSQFV-----GGHL-------AVAFAPDPEAELAA------ 840

                         650       660       670       680       690       700       710       720
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 861483604 1396 gLRTELMRAQRELgelvplrqkvAEQERAAQQLRAEKASYAEQLSMLKKAHG---LLAEEnrGLGERanlgRQFLEVELD 1472
Cdd:COG3096   841 -LRQRRSELEREL----------AQHRAQEQQLRQQLDQLKEQLQLLNKLLPqanLLADE--TLADR----LEELREELD 903

                         730       740       750       760       770       780       790       800
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 861483604 1473 QARE--KYIQElaavRGDAETRLAEMRQEVQSTTHELEVMTAKYEGAKvkvleerqrfqEERQKLTAQVEQL-EVFQREQ 1549
Cdd:COG3096   904 AAQEaqAFIQQ----HGKALAQLEPLVAVLQSDPEQFEQLQADYLQAK-----------EQQRRLKQQIFALsEVVQRRP 968

                         810       820       830       840       850       860       870       880
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 861483604 1550 TKKVEELSKKLADYDQASKVQQQKLKafqaqggESQQEAQRLQTQLNELQVQLSQKEQAaehykvqMEKAKTHYDAKKQQ 1629
Cdd:COG3096   969 HFSYEDAVGLLGENSDLNEKLRARLE-------QAEEARREAREQLRQAQAQYSQYNQV-------LASLKSSRDAKQQT 1034

                         890       900       910       920       930       940       950
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 861483604 1630 NQELQEQLQGLEQLQKENKELRAEAERlgQELQQAGLKTKeaeQTCRHLTAQVRSLEAQVAHADQQLRELGK 1701
Cdd:COG3096  1035 LQELEQELEELGVQADAEAEERARIRR--DELHEELSQNR---SRRSQLEKQLTRCEAEMDSLQKRLRKAER 1101
PRK11281 PRK11281
mechanosensitive channel MscK;
335-643 2.53e-07

mechanosensitive channel MscK;


Pssm-ID: 236892 [Multi-domain]  Cd Length: 1113  Bit Score: 56.07  E-value: 2.53e-07
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 861483604  335 QQLQgALN--ELTEEHSKATQQwvekqaHLEKELSTaLQDKKCLEEKNEilqgklsQLEERLAQLPESPRQEKGEvlgdv 412
Cdd:PRK11281   43 AQLD-ALNkqKLLEAEDKLVQQ------DLEQTLAL-LDKIDRQKEETE-------QLKQQLAQAPAKLRQAQAE----- 102

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 861483604  413 lqLESLKQEAATLA------TNNTQLQARVEMLENEQGQKEAQLLGERShfeeekqQLASLIT---NLQSSISNLSQAKE 483
Cdd:PRK11281  103 --LEALKDDNDEETretlstLSLRQLESRLAQTLDQLQNAQNDLAEYNS-------QLVSLQTqpeRAQAALYANSQRLQ 173

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 861483604  484 ELEQ---ASQAQGAKLNA-QVASLTAELTTLSATLQQQDQELAGLKQQAQKKQAQLAQSLQQQEQasqgLRHQVEQLSGS 559
Cdd:PRK11281  174 QIRNllkGGKVGGKALRPsQRVLLQAEQALLNAQNDLQRKSLEGNTQLQDLLQKQRDYLTARIQR----LEHQLQLLQEA 249

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 861483604  560 LKQKE-KQLEEAAREldasrrdhAQQLATAAKAQETSLrerdaacqqleaLEKEKAAKLEI---LQQQLQAANE-AQDSA 634
Cdd:PRK11281  250 INSKRlTLSEKTVQE--------AQSQDEAARIQANPL------------VAQELEINLQLsqrLLKATEKLNTlTQQNL 309

                         330
                  ....*....|....
gi 861483604  635 Q-----NSVTQAQR 643
Cdd:PRK11281  310 RvknwlDRLTQSER 323
EnvC COG4942
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, ...
 822-1042 2.77e-07

Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 443969 [Multi-domain]  Cd Length: 377  Bit Score: 55.16  E-value: 2.77e-07
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 861483604  822 QGETQYGLQEQLTTLKEEYEKSCQELRETKEKMAGIEAhselQIGQHQSELAQLHANLARALQQVQEKENRAQKLADDLS 901
Cdd:COG4942    18 QADAAAEAEAELEQLQQEIAELEKELAALKKEEKALLK----QLAALERRIAALARRIRALEQELAALEAELAELEKEIA 93

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 861483604  902 TLQEKMAATSKEVARLEALVRKAGEQQETASLeLLKEPPKTRDRESEWVE------EQQGQQLCSTQAALRAMEREAEQM 975
Cdd:COG4942    94 ELRAELEAQKEELAELLRALYRLGRQPPLALL-LSPEDFLDAVRRLQYLKylaparREQAEELRADLAELAALRAELEAE 172

                         170       180       190       200       210       220
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 861483604  976 GTELEKLRAALMESQGQQQEERGQQEREVARLTQERGQAEADLALEKAAKAELEMRLQNALNEQQAE 1042
Cdd:COG4942   173 RAELEALLAELEEERAALEALKAERQKLLARLEKELAELAAELAELQQEAEELEALIARLEAEAAAA 239
Smc COG1196
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ...
 1492-1713 2.94e-07

Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 440809 [Multi-domain]  Cd Length: 983  Bit Score: 56.10  E-value: 2.94e-07
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 861483604 1492 RLAEMRQEVQSTTHELEVMTAKYEGAKVKVLEERQRFQEERQKLTAQVEQLEVFQREqtkkVEELSKKLADYDQASKVQQ 1571
Cdd:COG1196   233 KLRELEAELEELEAELEELEAELEELEAELAELEAELEELRLELEELELELEEAQAE----EYELLAELARLEQDIARLE 308

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 861483604 1572 QKLKAFQAQGGESQQEAQRLQTQLNELQVQLSQKEQAAEHYKVQMEKAKTHYDAKKQQNQELQEQLQGLEQLQKENKELR 1651
Cdd:COG1196   309 ERRRELEERLEELEEELAELEEELEELEEELEELEEELEEAEEELEEAEAELAEAEEALLEAEAELAEAEEELEELAEEL 388

                         170       180       190       200       210       220
                  ....*....|....*....|....*....|....*....|....*....|....*....|..
gi 861483604 1652 AEAERLGQELQQAGLKTKEAEQtcRHLTAQVRSLEAQVAHADQQLRELGKFQVASDALKSRE 1713
Cdd:COG1196   389 LEALRAAAELAAQLEELEEAEE--ALLERLERLEEELEELEEALAELEEEEEEEEEALEEAA 448
EnvC COG4942
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, ...
 614-856 2.95e-07

Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 443969 [Multi-domain]  Cd Length: 377  Bit Score: 55.16  E-value: 2.95e-07
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 861483604  614 AAKLEILQQQLQAANEAQDSAQNSVTQAQREKAELSQKVEELHALIEAAHQEQCEAQTQVAALEARLKA-EQQKATEREK 692
Cdd:COG4942    19 ADAAAEAEAELEQLQQEIAELEKELAALKKEEKALLKQLAALERRIAALARRIRALEQELAALEAELAElEKEIAELRAE 98

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 861483604  693 VAQEKAQLQEQLWSLEESLKitkgsleeekcRAAAALEEHQHHISEMEAESRSLAEQHKQERKELEEEKAKRRGLgVQLQ 772
Cdd:COG4942    99 LEAQKEELAELLRALYRLGR-----------QPPLALLLSPEDFLDAVRRLQYLKYLAPARREQAEELRADLAEL-AALR 166

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 861483604  773 QLAETHQAETKALRQELAKARTSNNMAEREVELLVKEVKTWRKRYEDSQQgetqyGLQEQLTTLKEEYEKSCQELRETKE 852
Cdd:COG4942   167 AELEAERAELEALLAELEEERAALEALKAERQKLLARLEKELAELAAELA-----ELQQEAEELEALIARLEAEAAAAAE 241


                  ....
gi 861483604  853 KMAG 856
Cdd:COG4942   242 RTPA 245
COG4913 COG4913
Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];
414-850 3.31e-07

Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];


Pssm-ID: 443941 [Multi-domain]  Cd Length: 1089  Bit Score: 55.69  E-value: 3.31e-07
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 861483604  414 QLESLKQEAATLATNNTQLQARVEMLENEQGQKEAQLLGER-SHFEEEKQQLASLITNLQSSISNLSQAKEELEQASQAQ 492
Cdd:COG4913   256 PIRELAERYAAARERLAELEYLRAALRLWFAQRRLELLEAElEELRAELARLEAELERLEARLDALREELDELEAQIRGN 335

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 861483604  493 G----AKLNAQVASLTAELTTLSATLQQQDQ-------ELAGLKQQAQKKQAQLAQSLQQQEQASQGLRHQVEQLSGSLK 561
Cdd:COG4913   336 GgdrlEQLEREIERLERELEERERRRARLEAllaalglPLPASAEEFAALRAEAAALLEALEEELEALEEALAEAEAALR 415

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 861483604  562 QKEKQLEEAARELDASRR-----DHAQQLATAAKAQETSLRERDA--ACQQLEALEKEKA-----------AKLEIL--Q 621
Cdd:COG4913   416 DLRRELRELEAEIASLERrksniPARLLALRDALAEALGLDEAELpfVGELIEVRPEEERwrgaiervlggFALTLLvpP 495

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 861483604  622 QQLQAANEAQDS-----------AQNSVTQAQREKAE---LSQKVE-ELHALIEAAHQE--------QCE---------- 668
Cdd:COG4913   496 EHYAAALRWVNRlhlrgrlvyerVRTGLPDPERPRLDpdsLAGKLDfKPHPFRAWLEAElgrrfdyvCVDspeelrrhpr 575

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 861483604  669 --------------------------------AQTQVAALEARLKAEQQKATEREKVAQEKAQLQEQLWSLEESLKITKG 716
Cdd:COG4913   576 aitragqvkgngtrhekddrrrirsryvlgfdNRAKLAALEAELAELEEELAEAEERLEALEAELDALQERREALQRLAE 655

                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 861483604  717 SLEEEKCRAAAA--LEEHQHHISEMEAES---RSLAEQHKQERKELEEEKAKRRGLGVQLQQLAETHQAETKALRQELAK 791
Cdd:COG4913   656 YSWDEIDVASAEreIAELEAELERLDASSddlAALEEQLEELEAELEELEEELDELKGEIGRLEKELEQAEEELDELQDR 735

                         490       500       510       520       530
                  ....*....|....*....|....*....|....*....|....*....|....*....
gi 861483604  792 ARTSNNMAEREVELLVKEVktWRKRYEDSQQGETQYGLQEQLTTLKEEYEKSCQELRET 850
Cdd:COG4913   736 LEAAEDLARLELRALLEER--FAAALGDAVERELRENLEERIDALRARLNRAEEELERA 792
YhaN COG4717
Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown];
276-709 3.69e-07

Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown];


Pssm-ID: 443752 [Multi-domain]  Cd Length: 641  Bit Score: 55.54  E-value: 3.69e-07
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 861483604  276 RELEELRGKNESLTFRLHETLKQCQDLKTEKGQMDRKINQLSEENGDLSFKLREFASNLQQLQGALNELT--EEHSKATQ 353
Cdd:COG4717    53 KEADELFKPQGRKPELNLKELKELEEELKEAEEKEEEYAELQEELEELEEELEELEAELEELREELEKLEklLQLLPLYQ 132

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 861483604  354 QWVEKQAHLE------KELSTALQDKKCLEEKNEILQGKLSQLEERLAQLPESPRQEKGEVLGDVL-QLESLKQEAATLA 426
Cdd:COG4717   133 ELEALEAELAelperlEELEERLEELRELEEELEELEAELAELQEELEELLEQLSLATEEELQDLAeELEELQQRLAELE 212

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 861483604  427 TNNTQLQARVEMLENEQGQKEAQLLG----ERSHFEEEKQQLASLITNLQSSISNLSQAKEELEQASQAQGAKLNAQVAS 502
Cdd:COG4717   213 EELEEAQEELEELEEELEQLENELEAaaleERLKEARLLLLIAAALLALLGLGGSLLSLILTIAGVLFLVLGLLALLFLL 292

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 861483604  503 LTAELTTLSATLQQQDQELAGLKQQAQKKQAQLAQSLQQQEQASQGLRHQVEQLSgSLKQKEKQLEEAARELDASRRDHA 582
Cdd:COG4717   293 LAREKASLGKEAEELQALPALEELEEEELEELLAALGLPPDLSPEELLELLDRIE-ELQELLREAEELEEELQLEELEQE 371

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 861483604  583 QQlATAAKAQETSLRERDAACQQLEALEkEKAAKLEILQQQLQAANEAQDSAqnsvtQAQREKAELSQKVEELHALIEAA 662
Cdd:COG4717   372 IA-ALLAEAGVEDEEELRAALEQAEEYQ-ELKEELEELEEQLEELLGELEEL-----LEALDEEELEEELEELEEELEEL 444

                         410       420       430       440
                  ....*....|....*....|....*....|....*....|....*..
gi 861483604  663 HQEQCEAQTQVAALEARLKaEQQKATEREKVAQEKAQLQEQLWSLEE 709
Cdd:COG4717   445 EEELEELREELAELEAELE-QLEEDGELAELLQELEELKAELRELAE 490
sbcc TIGR00618
exonuclease SbcC; All proteins in this family for which functions are known are part of an ...
 1013-1721 4.51e-07

exonuclease SbcC; All proteins in this family for which functions are known are part of an exonuclease complex with sbcD homologs. This complex is involved in the initiation of recombination to regulate the levels of palindromic sequences in DNA. This family is based on the phylogenomic analysis of JA Eisen (1999, Ph.D. Thesis, Stanford University). [DNA metabolism, DNA replication, recombination, and repair]


Pssm-ID: 129705 [Multi-domain]  Cd Length: 1042  Bit Score: 55.36  E-value: 4.51e-07
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 861483604  1013 QAEADLALEKAAKAELEMRLQNALNEQQAEFANLQEALSRALSEKEGKDQELSKLCEQEAVQRME-LKELLQTVEQLKAQ 1091
Cdd:TIGR00618  151 QGEFAQFLKAKSKEKKELLMNLFPLDQYTQLALMEFAKKKSLHGKAELLTLRSQLLTLCTPCMPDtYHERKQVLEKELKH 230

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 861483604  1092 LAKKEKEQQQS------ARGASGENASGMGTQSEAVGKMEALRAKVSKLEQQCQQQQEEADSLARSLESERAFHVERD-- 1163
Cdd:TIGR00618  231 LREALQQTQQShayltqKREAQEEQLKKQQLLKQLRARIEELRAQEAVLEETQERINRARKAAPLAAHIKAVTQIEQQaq 310

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 861483604  1164 RALETLQGQLEEKARELGYSQAASASaqrelatlRAKAQDHSKAEEEWKAQVARGQQEAVRKGSLISSLEEEVSILNRqv 1243
Cdd:TIGR00618  311 RIHTELQSKMRSRAKLLMKRAAHVKQ--------QSSIEEQRRLLQTLHSQEIHIRDAHEVATSIREISCQQHTLTQH-- 380

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 861483604  1244 lekegeSKELKRLVIAESEKSQKLEERLRLLQMETASNSARAAERS------SALREEVQSLREEVEKQRAASENLRQEL 1317
Cdd:TIGR00618  381 ------IHTLQQQKTTLTQKLQSLCKELDILQREQATIDTRTSAFRdlqgqlAHAKKQQELQQRYAELCAAAITCTAQCE 454

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 861483604  1318 ASQAERAEELGQELKAWQEKFFQKEQalsaLQLEHTSTQALVSellpakHLCQQLQAEQVAAEKRHREeLEQSKQAAGGL 1397
Cdd:TIGR00618  455 KLEKIHLQESAQSLKEREQQLQTKEQ----IHLQETRKKAVVL------ARLLELQEEPCPLCGSCIH-PNPARQDIDNP 523

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 861483604  1398 RTELMRAQRELGELVPLRQKVAEQERAAQQLRAEKASYAEQLSMLKKAHGLLAEENRGLGERANLGRQFLEV------EL 1471
Cdd:TIGR00618  524 GPLTRRMQRGEQTYAQLETSEEDVYHQLTSERKQRASLKEQMQEIQQSFSILTQCDNRSKEDIPNLQNITVRlqdlteKL 603

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 861483604  1472 DQAREKYIQELAA--VRGDAETRLAEMRQEVQSTTHELEVMTAKYEGAKVKVLEERQR-----FQEERQKLTAQVEQLEV 1544
Cdd:TIGR00618  604 SEAEDMLACEQHAllRKLQPEQDLQDVRLHLQQCSQELALKLTALHALQLTLTQERVRehalsIRVLPKELLASRQLALQ 683

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 861483604  1545 FQREQTKKVEELSKKLADYDQASKVQQQKLKAFQAQGGESQQEAQRLQTQLNELQVQLSQKEQAAEHYKVQMEKAKTHYD 1624
Cdd:TIGR00618  684 KMQSEKEQLTYWKEMLAQCQTLLRELETHIEEYDREFNEIENASSSLGSDLAAREDALNQSLKELMHQARTVLKARTEAH 763

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 861483604  1625 AKKQQNQELQEQLQGLEQ-----LQKENKELRAEAERLGQELQQAGLKTKEAEQTcrhLTAQVRSLEAQVAHADQQLREL 1699
Cdd:TIGR00618  764 FNNNEEVTAALQTGAELShlaaeIQFFNRLREEDTHLLKTLEAEIGQEIPSDEDI---LNLQCETLVQEEEQFLSRLEEK 840

                          730       740
                   ....*....|....*....|..
gi 861483604  1700 GKFQVASDALKSREPQAKPQLD 1721
Cdd:TIGR00618  841 SATLGEITHQLLKYEECSKQLA 862
CCDC158 pfam15921
Coiled-coil domain-containing protein 158; CCDC158 is a family of proteins found in eukaryotes. ...
 327-1086 4.66e-07

Coiled-coil domain-containing protein 158; CCDC158 is a family of proteins found in eukaryotes. The function is not known.


Pssm-ID: 464943 [Multi-domain]  Cd Length: 1112  Bit Score: 55.51  E-value: 4.66e-07
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 861483604   327 LREFASNLQQLQGALNELTEEHSKatQQWVEKQAHLekELSTALQDKkcleeknEILQGKLSQLEERLAQLPESPRQEKG 406
Cdd:pfam15921   80 LEEYSHQVKDLQRRLNESNELHEK--QKFYLRQSVI--DLQTKLQEM-------QMERDAMADIRRRESQSQEDLRNQLQ 148

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 861483604   407 EVLGDVLQLESLKQEaaTLATNNTQLQARVEMLENEQG-------------QKEAQLLGERS-----HFEEEKQQLASLI 468
Cdd:pfam15921  149 NTVHELEAAKCLKED--MLEDSNTQIEQLRKMMLSHEGvlqeirsilvdfeEASGKKIYEHDsmstmHFRSLGSAISKIL 226

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 861483604   469 TNLQSSISNL---------------SQAKEELEQASQAQGAKLNAQVASLTAELTTLSATLQQQDQELAGLKQQAQKKQA 533
Cdd:pfam15921  227 RELDTEISYLkgrifpvedqlealkSESQNKIELLLQQHQDRIEQLISEHEVEITGLTEKASSARSQANSIQSQLEIIQE 306

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 861483604   534 QLAQSLQQQEQASQGLRHQVEQLSGSLKQKEKQLEEAARELDASRRDHAQQLATAAKAQETSLRERDAACQQLEAL---- 609
Cdd:pfam15921  307 QARNQNSMYMRQLSDLESTVSQLRSELREAKRMYEDKIEELEKQLVLANSELTEARTERDQFSQESGNLDDQLQKLladl 386

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 861483604   610 -EKEKAAKLEILQQQLQAANEAQDSAqnSVTQAQREKAELSQKVEELHALIEAAHQEqCEAQtqvaaLEARLKAEQQKAT 688
Cdd:pfam15921  387 hKREKELSLEKEQNKRLWDRDTGNSI--TIDHLRRELDDRNMEVQRLEALLKAMKSE-CQGQ-----MERQMAAIQGKNE 458

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 861483604   689 EREKVAQEKAQLQ---EQLWSLEESLKITKGSLEEEKCRAA---AALEEHQHHISEMEAESRSLAEQHKQERKELEEEKA 762
Cdd:pfam15921  459 SLEKVSSLTAQLEstkEMLRKVVEELTAKKMTLESSERTVSdltASLQEKERAIEATNAEITKLRSRVDLKLQELQHLKN 538

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 861483604   763 KrrglGVQLQQLaethQAETKALRQELAKARTSNNMAEREVELLVKEVktwrkryedSQQGETQYGLQEQLTTLKEEYEK 842
Cdd:pfam15921  539 E----GDHLRNV----QTECEALKLQMAEKDKVIEILRQQIENMTQLV---------GQHGRTAGAMQVEKAQLEKEIND 601

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 861483604   843 SCQELRE---TKEKMAGIEAHSELQIGQHQSELAQLHANLARALQQVQEKENRAQKLADDLSTLQEKMAATSKEVARLEA 919
Cdd:pfam15921  602 RRLELQEfkiLKDKKDAKIRELEARVSDLELEKVKLVNAGSERLRAVKDIKQERDQLLNEVKTSRNELNSLSEDYEVLKR 681

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 861483604   920 LVRKAGEQQETASLEL---LKEPPKTRDRESEWVEEQQGQQLCSTQAALrAMEREAEQMGTELEKLRAA---LMESQGQQ 993
Cdd:pfam15921  682 NFRNKSEEMETTTNKLkmqLKSAQSELEQTRNTLKSMEGSDGHAMKVAM-GMQKQITAKRGQIDALQSKiqfLEEAMTNA 760

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 861483604   994 QEERGQQEREVARLTQERgqaeADLALEKAAKA-ELEMrLQNALNEQQAEFANLQEALSRAlSEKEGKDQELSKLCEQEA 1072
Cdd:pfam15921  761 NKEKHFLKEEKNKLSQEL----STVATEKNKMAgELEV-LRSQERRLKEKVANMEVALDKA-SLQFAECQDIIQRQEQES 834

                          810
                   ....*....|....
gi 861483604  1073 VqRMELKELLQTVE 1086
Cdd:pfam15921  835 V-RLKLQHTLDVKE 847
PRK02224 PRK02224
DNA double-strand break repair Rad50 ATPase;
215-721 6.26e-07

DNA double-strand break repair Rad50 ATPase;


Pssm-ID: 179385 [Multi-domain]  Cd Length: 880  Bit Score: 54.66  E-value: 6.26e-07
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 861483604  215 QMRRLKKQLADERNNRDELELELAEHRklltEKDAQISMMQQRIDRLallNEKQAASPlepRELEELRGKNESLTFRLHE 294
Cdd:PRK02224  221 EIERYEEQREQARETRDEADEVLEEHE----ERREELETLEAEIEDL---RETIAETE---REREELAEEVRDLRERLEE 290

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 861483604  295 TLKQCQDLKTEKGQMDRKINQLSEENGDLSFKLREFASNLQQLQGALNELTEEHSKAT----------QQWVEKQAHLEK 364
Cdd:PRK02224  291 LEEERDDLLAEAGLDDADAEAVEARREELEDRDEELRDRLEECRVAAQAHNEEAESLRedaddleeraEELREEAAELES 370

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 861483604  365 ELSTALQDKKCLEEKNEILQGKLSQLEERLAQLP----------ESPRQEKGEVLGDVLQLESLKQEAATLATNNTQLQA 434
Cdd:PRK02224  371 ELEEAREAVEDRREEIEELEEEIEELRERFGDAPvdlgnaedflEELREERDELREREAELEATLRTARERVEEAEALLE 450

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 861483604  435 RVEMLENEQGQKEAQLLGERSHFEEEKQQLASLITNLQSSISNLSQAKEELEQASQA--QGAKLNAQVASLTAELTTLSA 512
Cdd:PRK02224  451 AGKCPECGQPVEGSPHVETIEEDRERVEELEAELEDLEEEVEEVEERLERAEDLVEAedRIERLEERREDLEELIAERRE 530

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 861483604  513 TLQQQDQELAGLKQQAQKKQAQLAQSLQQQEQasqgLRHQVEQLSGSLKQKEKQLEEAARELDASRRDHAQQLATAAKAQ 592
Cdd:PRK02224  531 TIEEKRERAEELRERAAELEAEAEEKREAAAE----AEEEAEEAREEVAELNSKLAELKERIESLERIRTLLAAIADAED 606

                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 861483604  593 E-TSLRERDAACQQLEALEKEKAAKLEILQQQLQAANEAqdsaqNSVTQAQREKAELSQKVEELHALIEAAHQEQCEAQT 671
Cdd:PRK02224  607 EiERLREKREALAELNDERRERLAEKRERKRELEAEFDE-----ARIEEAREDKERAEEYLEQVEEKLDELREERDDLQA 681

                         490       500       510       520       530
                  ....*....|....*....|....*....|....*....|....*....|
gi 861483604  672 QVAALEARLKAEQQKATEREKVAQEKAQLqEQLWSLEESLKITKGSLEEE 721
Cdd:PRK02224  682 EIGAVENELEELEELRERREALENRVEAL-EALYDEAEELESMYGDLRAE 730
EnvC COG4942
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, ...
 661-915 7.26e-07

Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 443969 [Multi-domain]  Cd Length: 377  Bit Score: 53.61  E-value: 7.26e-07
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 861483604  661 AAHQEQCEAQTQVAALEARLKAEQQkatEREKVAQEKAQLQEQLWSLEESLKitkgsleeekcRAAAALEEHQHHISEME 740
Cdd:COG4942    17 AQADAAAEAEAELEQLQQEIAELEK---ELAALKKEEKALLKQLAALERRIA-----------ALARRIRALEQELAALE 82

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 861483604  741 AESRSLAEQHKQERKELEEEKAKRRGLGVQLQQLAETHQAETKALRQELAKARTSNNMAEREVEllvkevktwrkryEDS 820
Cdd:COG4942    83 AELAELEKEIAELRAELEAQKEELAELLRALYRLGRQPPLALLLSPEDFLDAVRRLQYLKYLAP-------------ARR 149

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 861483604  821 QQGETQYGLQEQLTTLKEEYEKSCQELRETKEKMAGIEAHSELQIGQHQSELAQLHANLARALQQVQEKENRAQKLADDL 900
Cdd:COG4942   150 EQAEELRADLAELAALRAELEAERAELEALLAELEEERAALEALKAERQKLLARLEKELAELAAELAELQQEAEELEALI 229

                         250
                  ....*....|....*
gi 861483604  901 STLQEKMAATSKEVA 915
Cdd:COG4942   230 ARLEAEAAAAAERTP 244
YhaN COG4717
Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown];
334-781 8.58e-07

Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown];


Pssm-ID: 443752 [Multi-domain]  Cd Length: 641  Bit Score: 54.00  E-value: 8.58e-07
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 861483604  334 LQQLQGALNEL----------TEEHSKATQQWVEKQAHLEKELSTALQDKKCLEEKNEILQGKLSQLEERLAQL------ 397
Cdd:COG4717    48 LERLEKEADELfkpqgrkpelNLKELKELEEELKEAEEKEEEYAELQEELEELEEELEELEAELEELREELEKLekllql 127

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 861483604  398 ---PESPRQEKGEVLGDVLQLESLKQEAATLAtnntQLQARVEMLENEQGQKEAQLLGERSHF-EEEKQQLASLITNLQS 473
Cdd:COG4717   128 lplYQELEALEAELAELPERLEELEERLEELR----ELEEELEELEAELAELQEELEELLEQLsLATEEELQDLAEELEE 203

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 861483604  474 SISNLSQAKEELEQAsQAQGAKLNAQVASLTAELTTLSATLQQQDQELAGLKQQAQKKQAQLAQSLQQQEQASQGLRHQV 553
Cdd:COG4717   204 LQQRLAELEEELEEA-QEELEELEEELEQLENELEAAALEERLKEARLLLLIAAALLALLGLGGSLLSLILTIAGVLFLV 282

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 861483604  554 EQLSGSLKQKEKQLEEAARELDASRRDHAQQLATAAKAQETSLRERDAACQQLEALEKEKAAKLEILQQQLQAANEAQDS 633
Cdd:COG4717   283 LGLLALLFLLLAREKASLGKEAEELQALPALEELEEEELEELLAALGLPPDLSPEELLELLDRIEELQELLREAEELEEE 362

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 861483604  634 AQNSVTQAQREKAELSQKVEELHALIEAA--HQEQCEAQTQVAALEARLkAEQQKATEREKVAQEKAQLQEQLWSLEESL 711
Cdd:COG4717   363 LQLEELEQEIAALLAEAGVEDEEELRAALeqAEEYQELKEELEELEEQL-EELLGELEELLEALDEEELEEELEELEEEL 441

                         410       420       430       440       450       460       470
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 861483604  712 KitkgSLEEEKCRAAAALEEHQHHISEME-----AESRSLAEQHKQERKELEEEKAKRRGLGVQLQQLAETHQAE 781
Cdd:COG4717   442 E----ELEEELEELREELAELEAELEQLEedgelAELLQELEELKAELRELAEEWAALKLALELLEEAREEYREE 512
PRK02224 PRK02224
DNA double-strand break repair Rad50 ATPase;
1159-1662 9.80e-07

DNA double-strand break repair Rad50 ATPase;


Pssm-ID: 179385 [Multi-domain]  Cd Length: 880  Bit Score: 54.28  E-value: 9.80e-07
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 861483604 1159 HVERDRALETLQGQLEEkarelgySQAASASAQRELATLRAKAQDHSKAEEEwkaqvARGQQEAVRKGSLISSLEEEVSI 1238
Cdd:PRK02224  246 HEERREELETLEAEIED-------LRETIAETEREREELAEEVRDLRERLEE-----LEEERDDLLAEAGLDDADAEAVE 313

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 861483604 1239 LNRQVLEKEgeskelkrlviaESEKSQKLEERlRLLQMETASNSARAAERSSALREEVQSLREEVEKQRAASENLRQELA 1318
Cdd:PRK02224  314 ARREELEDR------------DEELRDRLEEC-RVAAQAHNEEAESLREDADDLEERAEELREEAAELESELEEAREAVE 380

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 861483604 1319 SQAERAEELGQELKAWQEKFFQKEQALSALQLEHtstQALVSELLPAKHLCQQLQAEQVAAEKRHREE---LEQSKQAAG 1395
Cdd:PRK02224  381 DRREEIEELEEEIEELRERFGDAPVDLGNAEDFL---EELREERDELREREAELEATLRTARERVEEAealLEAGKCPEC 457

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 861483604 1396 GLRTELMRAQRELGElvpLRQKVAEQERAAQQLRAEKASYAEQLSMLKKAHGLLAEENRgLGERanlgRQFLEVELDQAR 1475
Cdd:PRK02224  458 GQPVEGSPHVETIEE---DRERVEELEAELEDLEEEVEEVEERLERAEDLVEAEDRIER-LEER----REDLEELIAERR 529

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 861483604 1476 EKyiqelAAVRGDAETRLAEMRQEVQSTTHELEVMTAKYEGAKVKVLEERQRFQEERQKLTAQVEQLEvfqreqtkKVEE 1555
Cdd:PRK02224  530 ET-----IEEKRERAEELRERAAELEAEAEEKREAAAEAEEEAEEAREEVAELNSKLAELKERIESLE--------RIRT 596

                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 861483604 1556 LSKKLADYDQASKVQQQKLKAFQAQGGESQQEAQRLQTQLNELQV--------QLSQKEQAAEHYkvqMEKAKTHYDAKK 1627
Cdd:PRK02224  597 LLAAIADAEDEIERLREKREALAELNDERRERLAEKRERKRELEAefdearieEAREDKERAEEY---LEQVEEKLDELR 673

                         490       500       510
                  ....*....|....*....|....*....|....*
gi 861483604 1628 QQNQELQEQLQGLEQLQKENKELRAEAERLGQELQ 1662
Cdd:PRK02224  674 EERDDLQAEIGAVENELEELEELRERREALENRVE 708
EnvC COG4942
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, ...
 458-675 1.27e-06

Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 443969 [Multi-domain]  Cd Length: 377  Bit Score: 52.84  E-value: 1.27e-06
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 861483604  458 EEEKQQLASLITNLQSSISNLSQAKEElEQASQAQGAKLNAQVASLTAELTTLSATLQQQDQELAGLKQQAQKKQAQLAQ 537
Cdd:COG4942    23 AEAEAELEQLQQEIAELEKELAALKKE-EKALLKQLAALERRIAALARRIRALEQELAALEAELAELEKEIAELRAELEA 101

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 861483604  538 SLQQQEQASQGLRHQVEQLSGSLKQKEKQLEEAARELD------ASRRDHAQQLATAAKAQETSLRERDAACQQLEALEK 611
Cdd:COG4942   102 QKEELAELLRALYRLGRQPPLALLLSPEDFLDAVRRLQylkylaPARREQAEELRADLAELAALRAELEAERAELEALLA 181

                         170       180       190       200       210       220
                  ....*....|....*....|....*....|....*....|....*....|....*....|....
gi 861483604  612 EKAAKLEILQQQLQAANEAQDSAQNSVTQAQREKAELSQKVEELHALIEAAHQEQCEAQTQVAA 675
Cdd:COG4942   182 ELEEERAALEALKAERQKLLARLEKELAELAAELAELQQEAEELEALIARLEAEAAAAAERTPA 245
sbcc TIGR00618
exonuclease SbcC; All proteins in this family for which functions are known are part of an ...
 483-1101 1.55e-06

exonuclease SbcC; All proteins in this family for which functions are known are part of an exonuclease complex with sbcD homologs. This complex is involved in the initiation of recombination to regulate the levels of palindromic sequences in DNA. This family is based on the phylogenomic analysis of JA Eisen (1999, Ph.D. Thesis, Stanford University). [DNA metabolism, DNA replication, recombination, and repair]


Pssm-ID: 129705 [Multi-domain]  Cd Length: 1042  Bit Score: 53.43  E-value: 1.55e-06
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 861483604   483 EELEQASQAQGAKLNAQVASLTAELTTLSATLQQQDQELAglkqqaqKKQAQLAQSLQQQEQASQGLRHQVEQLSGSLKQ 562
Cdd:TIGR00618  197 ELLTLRSQLLTLCTPCMPDTYHERKQVLEKELKHLREALQ-------QTQQSHAYLTQKREAQEEQLKKQQLLKQLRARI 269

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 861483604   563 KEKQLEEAARELDASRRDHAQQLATAAKAQETSLRERDAACQQLEALEKEKAAKLEILQQQLQAANEAQDSAQNSVTQAQ 642
Cdd:TIGR00618  270 EELRAQEAVLEETQERINRARKAAPLAAHIKAVTQIEQQAQRIHTELQSKMRSRAKLLMKRAAHVKQQSSIEEQRRLLQT 349

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 861483604   643 REKAELSQKVEELHALIEAAHQEQCEAQTQvaaleaRLKAEQQKATEREKVAQEKAQLQEQLWSLE---ESLKITKGSLE 719
Cdd:TIGR00618  350 LHSQEIHIRDAHEVATSIREISCQQHTLTQ------HIHTLQQQKTTLTQKLQSLCKELDILQREQatiDTRTSAFRDLQ 423

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 861483604   720 EEKCRAAAALEEHQHHISEMEAESRSLAEQHKQERKELEEEKAKRRGLGVQLQQLAETHQAETKALRQELAKArtsNNMA 799
Cdd:TIGR00618  424 GQLAHAKKQQELQQRYAELCAAAITCTAQCEKLEKIHLQESAQSLKEREQQLQTKEQIHLQETRKKAVVLARL---LELQ 500

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 861483604   800 EREVELLVKEVKTWRKRYEDSQQGETQ---YGLQEQLTTLKEEYEKSCQELRETKEKMAGIEAHSELQIgQHQSELAQLH 876
Cdd:TIGR00618  501 EEPCPLCGSCIHPNPARQDIDNPGPLTrrmQRGEQTYAQLETSEEDVYHQLTSERKQRASLKEQMQEIQ-QSFSILTQCD 579

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 861483604   877 ANLARALQQVQEKENRAQKLADDLSTLQEKMAATSKEVAR----LEALVRKAGEQQETASLELLKEPPKTRDRE------ 946
Cdd:TIGR00618  580 NRSKEDIPNLQNITVRLQDLTEKLSEAEDMLACEQHALLRklqpEQDLQDVRLHLQQCSQELALKLTALHALQLtltqer 659

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 861483604   947 ----SEWVEEQQGQQLCSTQAALRAMEREAEQMGTELEKLrAALMESQGQQQEERGQQEREVARLTQERGQAEADLALEK 1022
Cdd:TIGR00618  660 vrehALSIRVLPKELLASRQLALQKMQSEKEQLTYWKEML-AQCQTLLRELETHIEEYDREFNEIENASSSLGSDLAARE 738

                          570       580       590       600       610       620       630
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 861483604  1023 AAKAELEMRLQNALNEQQAEFANLQEALSRALSEKEGKDQELSKLCEQEAVQRMELKELLQTVEQLKAQLAKKEKEQQQ 1101
Cdd:TIGR00618  739 DALNQSLKELMHQARTVLKARTEAHFNNNEEVTAALQTGAELSHLAAEIQFFNRLREEDTHLLKTLEAEIGQEIPSDED 817
PRK10929 PRK10929
putative mechanosensitive channel protein; Provisional
 779-1134 1.57e-06

putative mechanosensitive channel protein; Provisional


Pssm-ID: 236798 [Multi-domain]  Cd Length: 1109  Bit Score: 53.52  E-value: 1.57e-06
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 861483604  779 QAETKALRQELAKARTSNNMAEREVELLVKEVKTWRKRYEDSQQGETQYglqeqlTTLKEEYEKSCQELRETKEKMAGI- 857
Cdd:PRK10929   22 APDEKQITQELEQAKAAKTPAQAEIVEALQSALNWLEERKGSLERAKQY------QQVIDNFPKLSAELRQQLNNERDEp 95

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 861483604  858 -EAHSELQIGQHQSELAQLHANLARALQQVQEKENRAQKLADDLSTLQEKMAATSKEVARLEalvRKAGEQQETASLell 936
Cdd:PRK10929   96 rSVPPNMSTDALEQEILQVSSQLLEKSRQAQQEQDRAREISDSLSQLPQQQTEARRQLNEIE---RRLQTLGTPNTP--- 169

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 861483604  937 keppktrdresewVEEQQGQQLCSTQAALRAM--EREAEQMGT----ELEKLRAALMESQGQQQEERGQQEREvaRLTQE 1010
Cdd:PRK10929  170 -------------LAQAQLTALQAESAALKALvdELELAQLSAnnrqELARLRSELAKKRSQQLDAYLQALRN--QLNSQ 234

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 861483604 1011 RgQAEADLALEKAakaelEMrlqnaLNEQQAEfanlqeaLSRALSEKEGKDQELSKLCEQEAvQRMELKELLQtveqlka 1090
Cdd:PRK10929  235 R-QREAERALEST-----EL-----LAEQSGD-------LPKSIVAQFKINRELSQALNQQA-QRMDLIASQQ------- 288

                         330       340       350       360
                  ....*....|....*....|....*....|....*....|....
gi 861483604 1091 QLAKKEKEQQQSARGASGENASGMGTqSEAVGkmEALRAKVSKL 1134
Cdd:PRK10929  289 RQAASQTLQVRQALNTLREQSQWLGV-SNALG--EALRAQVARL 329
DUF5401 pfam17380
Family of unknown function (DUF5401); This is a family of unknown function found in ...
 549-848 1.60e-06

Family of unknown function (DUF5401); This is a family of unknown function found in Chromadorea.


Pssm-ID: 375164 [Multi-domain]  Cd Length: 722  Bit Score: 53.20  E-value: 1.60e-06
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 861483604   549 LRHQVEQLSGSLKQKeKQLEEAAR----ELDASRRDHAQQLATAAK--------AQETSLRERDAACQQLEALEKEKAAK 616
Cdd:pfam17380  301 LRQEKEEKAREVERR-RKLEEAEKarqaEMDRQAAIYAEQERMAMErereleriRQEERKRELERIRQEEIAMEISRMRE 379

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 861483604   617 LEILQQQLQAANEAQDSAQNSVTQAQREKAELSQKVEELHALIEAAHQEQCEA-QTQVAALEarlkaeQQKATEREKVAQ 695
Cdd:pfam17380  380 LERLQMERQQKNERVRQELEAARKVKILEEERQRKIQQQKVEMEQIRAEQEEArQREVRRLE------EERAREMERVRL 453

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 861483604   696 EKAQLQEQLWSLEESlkitkgslEEEKCRAAAALEEHQHHISEMEAESRSLAEQHKQERKELEEEKAKRRGLGVQLQQLA 775
Cdd:pfam17380  454 EEQERQQQVERLRQQ--------EEERKRKKLELEKEKRDRKRAEEQRRKILEKELEERKQAMIEEERKRKLLEKEMEER 525

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 861483604   776 ETHQAETKALRQELAKARTSNNMAER-EVELLVKEVKTWRKRYE-------------DSQQGETQYGLQEQLTTLKEEYE 841
Cdd:pfam17380  526 QKAIYEEERRREAEEERRKQQEMEERrRIQEQMRKATEERSRLEamereremmrqivESEKARAEYEATTPITTIKPIYR 605


                   ....*..
gi 861483604   842 KSCQELR 848
Cdd:pfam17380  606 PRISEYQ 612
COG2433 COG2433
Possible nuclease of RNase H fold, RuvC/YqgF family [General function prediction only];
1199-1327 2.54e-06

Possible nuclease of RNase H fold, RuvC/YqgF family [General function prediction only];


Pssm-ID: 441980 [Multi-domain]  Cd Length: 644  Bit Score: 52.55  E-value: 2.54e-06
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 861483604 1199 AKAQDHSKAEEEWKAQVARGQQEAVRkgsliSSLEEEVSILNRQVLEKEGESKELKRLVIAESEKSQKLEERLRLLQMEt 1278
Cdd:COG2433   383 EELIEKELPEEEPEAEREKEHEEREL-----TEEEEEIRRLEEQVERLEAEVEELEAELEEKDERIERLERELSEARSE- 456

                          90       100       110       120
                  ....*....|....*....|....*....|....*....|....*....
gi 861483604 1279 ASNSARAAERSSALREEVQSLREEVEKQRAASENLRQELasqaERAEEL 1327
Cdd:COG2433   457 ERREIRKDREISRLDREIERLERELEEERERIEELKRKL----ERLKEL 501
COG4913 COG4913
Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];
432-1098 2.54e-06

Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];


Pssm-ID: 443941 [Multi-domain]  Cd Length: 1089  Bit Score: 53.00  E-value: 2.54e-06
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 861483604  432 LQARVEMLE--NEQGQKEAQLLGERSHFEEEKQQLASLitnlqssisnlsQAKEELEQASQAQgAKLNAQVASLTAELTT 509
Cdd:COG4913   247 AREQIELLEpiRELAERYAAARERLAELEYLRAALRLW------------FAQRRLELLEAEL-EELRAELARLEAELER 313

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 861483604  510 LSATLQQQDQELaglkqqaqkkqaqlaqslqqqeqasQGLRHQVEQLSG----SLKQKEKQLEEAARELDASRRDHAQQL 585
Cdd:COG4913   314 LEARLDALREEL-------------------------DELEAQIRGNGGdrleQLEREIERLERELEERERRRARLEALL 368

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 861483604  586 ATAAKAQETSLRErdaacqqLEALEKEKAAKLEILQQQLQAANEAQDSAQNSVTQAQREKAELSQKVEELHA---LIEAA 662
Cdd:COG4913   369 AALGLPLPASAEE-------FAALRAEAAALLEALEEELEALEEALAEAEAALRDLRRELRELEAEIASLERrksNIPAR 441

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 861483604  663 HQ---EQCEAQTQVAALEARLKAE--QQKATERE-KVAQEKAqlqeqLWSLEESLkitkgsLEEEKCRAAAA-------- 728
Cdd:COG4913   442 LLalrDALAEALGLDEAELPFVGEliEVRPEEERwRGAIERV-----LGGFALTL------LVPPEHYAAALrwvnrlhl 510

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 861483604  729 --------LEEHQHHISEMEAESRSLAEqhkqerkELE-EEKAKRRGLGVQLQQLAETHQAET-KALRQElAKARTSNNM 798
Cdd:COG4913   511 rgrlvyerVRTGLPDPERPRLDPDSLAG-------KLDfKPHPFRAWLEAELGRRFDYVCVDSpEELRRH-PRAITRAGQ 582

                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 861483604  799 aerevellvkeVKTWRKRYE--DSQQGETQYGL----QEQLTTLKEEYEKSCQELRETKEKMAGIEAhselqigqhQSEL 872
Cdd:COG4913   583 -----------VKGNGTRHEkdDRRRIRSRYVLgfdnRAKLAALEAELAELEEELAEAEERLEALEA---------ELDA 642

                         490       500       510       520       530       540       550       560
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 861483604  873 AQLHANLARALQQVQEKENRAQKLADDLSTLQEKMA---ATSKEVARLEALVRKAGEQQETASLELLKEPPKTRDRESEW 949
Cdd:COG4913   643 LQERREALQRLAEYSWDEIDVASAEREIAELEAELErldASSDDLAALEEQLEELEAELEELEEELDELKGEIGRLEKEL 722

                         570       580       590       600       610       620       630       640
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 861483604  950 VEEQQGQQLCSTQAAlRAMEREAEQMGTELEKLRAALMESqgqqqeergqqerevARLTQERGQAEADLALEKAAKAELE 1029
Cdd:COG4913   723 EQAEEELDELQDRLE-AAEDLARLELRALLEERFAAALGD---------------AVERELRENLEERIDALRARLNRAE 786

                         650       660       670       680       690       700       710
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 861483604 1030 MRLQNALNEQQAEFANLQEALSRALSEKEGKDQELSKLCEQEAVQRME-LKELLQT-----VEQLKAQLAKKEKE 1098
Cdd:COG4913   787 EELERAMRAFNREWPAETADLDADLESLPEYLALLDRLEEDGLPEYEErFKELLNEnsiefVADLLSKLRRAIRE 861
YhaN COG4717
Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown];
1164-1598 3.02e-06

Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown];


Pssm-ID: 443752 [Multi-domain]  Cd Length: 641  Bit Score: 52.46  E-value: 3.02e-06
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 861483604 1164 RALETLQGQLEEKARELGYSQAASASAQRELATLRAKAQDHSKAEEEWKAQVARGQQEAVrkgslISSLEEEVSILNRQV 1243
Cdd:COG4717    81 KEAEEKEEEYAELQEELEELEEELEELEAELEELREELEKLEKLLQLLPLYQELEALEAE-----LAELPERLEELEERL 155

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 861483604 1244 LEKEGESKELKRLVIAESEKSQKLEERLRLLQMETASNSARAAERSSALREEVQSLREEVEKQRAASENLRQELASQAER 1323
Cdd:COG4717   156 EELRELEEELEELEAELAELQEELEELLEQLSLATEEELQDLAEELEELQQRLAELEEELEEAQEELEELEEELEQLENE 235

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 861483604 1324 AEELGQELKAWQEKFFQKEQA-LSALQLEHTSTQALVSELLPAKHLCQQLQAEQVAAEKRHREELEQSKQAAGGLRTELM 1402
Cdd:COG4717   236 LEAAALEERLKEARLLLLIAAaLLALLGLGGSLLSLILTIAGVLFLVLGLLALLFLLLAREKASLGKEAEELQALPALEE 315

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 861483604 1403 RAQRELGELVplrqkvaeqERAAQQLRAEKASYAEQLSMLKKAHGLLAEENRglgeranLGRQFLEVELDQAREKYIQEL 1482
Cdd:COG4717   316 LEEEELEELL---------AALGLPPDLSPEELLELLDRIEELQELLREAEE-------LEEELQLEELEQEIAALLAEA 379

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 861483604 1483 AAVRGDAETRLAEMRQEVQSTTHELEVMTAKYEGAKVKVLEERQRFQEERqkLTAQVEQLEVFQREQTKKVEELSKKLAD 1562
Cdd:COG4717   380 GVEDEEELRAALEQAEEYQELKEELEELEEQLEELLGELEELLEALDEEE--LEEELEELEEELEELEEELEELREELAE 457

                         410       420       430
                  ....*....|....*....|....*....|....*.
gi 861483604 1563 YDQASKVQQQKLKAFQAqggesQQEAQRLQTQLNEL 1598
Cdd:COG4717   458 LEAELEQLEEDGELAEL-----LQELEELKAELREL 488
DUF3584 pfam12128
Protein of unknown function (DUF3584); This protein is found in bacteria and eukaryotes. ...
 206-789 3.08e-06

Protein of unknown function (DUF3584); This protein is found in bacteria and eukaryotes. Proteins in this family are typically between 943 to 1234 amino acids in length. This family contains a P-loop motif suggesting it is a nucleotide binding protein. It may be involved in replication.


Pssm-ID: 432349 [Multi-domain]  Cd Length: 1191  Bit Score: 52.53  E-value: 3.08e-06
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 861483604   206 GDILQTPQFQmrrlkkqlADERNNRDELELELAEHRKLLTEKDAQISMMQQRIDR-LALLNEKQAASPLE-PRELEELRG 283
Cdd:pfam12128  344 ADQEQLPSWQ--------SELENLEERLKALTGKHQDVTAKYNRRRSKIKEQNNRdIAGIKDKLAKIREArDRQLAVAED 415

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 861483604   284 KNESLTFRLHEtlkqcqdlktekgQMDRKINQLSEENgdlsfklREFASNLQQLQGALNELTEEHSKATQQ--WVEKQAH 361
Cdd:pfam12128  416 DLQALESELRE-------------QLEAGKLEFNEEE-------YRLKSRLGELKLRLNQATATPELLLQLenFDERIER 475

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 861483604   362 LEKELSTALQDKKCLEEKNEILQGKLSQLEERLAQLPESPRQEKGEVLGDVLQL--------ESLKQEAATLATNNTQLQ 433
Cdd:pfam12128  476 AREEQEAANAEVERLQSELRQARKRRDQASEALRQASRRLEERQSALDELELQLfpqagtllHFLRKEAPDWEQSIGKVI 555

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 861483604   434 AR--------VEMLENEQGQKEAQLLGERSHFEE-EKQQLASLITNLQSSISNLS---QAKEELEQASQAQGAKLNAQVA 501
Cdd:pfam12128  556 SPellhrtdlDPEVWDGSVGGELNLYGVKLDLKRiDVPEWAASEEELRERLDKAEealQSAREKQAAAEEQLVQANGELE 635

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 861483604   502 SLTAELTTLSATLQQQDQELAG----LKQQAQKKQAQLAQSLQQQEQASQGLRHQVEQLSGSLKQKEKQLEEAARELDAS 577
Cdd:pfam12128  636 KASREETFARTALKNARLDLRRlfdeKQSEKDKKNKALAERKDSANERLNSLEAQLKQLDKKHQAWLEEQKEQKREARTE 715

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 861483604   578 RRDHAQQLATAAKAQETSLRerdaacQQLEALEKEKAAKLEILQQQLQAANEAQDSAQNSVTQAQREKAELSQKVEelha 657
Cdd:pfam12128  716 KQAYWQVVEGALDAQLALLK------AAIAARRSGAKAELKALETWYKRDLASLGVDPDVIAKLKREIRTLERKIE---- 785

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 861483604   658 liEAAHQEQCEAQTQVAALEARLKAEQQKATEREKVAQEKAQLQEQLWSLEESLKITKGSLEEEKCRAAAALEEHQHHIS 737
Cdd:pfam12128  786 --RIAVRRQEVLRYFDWYQETWLQRRPRLATQLSNIERAISELQQQLARLIADTKLRRAKLEMERKASEKQQVRLSENLR 863

                          570       580       590       600       610
                   ....*....|....*....|....*....|....*....|....*....|...
gi 861483604   738 EMEAESRSLAEQHK-QERKELEEEKAKRRGlgvQLQQLAETHQAETKALRQEL 789
Cdd:pfam12128  864 GLRCEMSKLATLKEdANSEQAQGSIGERLA---QLEDLKLKRDYLSESVKKYV 913
Myosin_tail_1 pfam01576
Myosin tail; The myosin molecule is a multi-subunit complex made up of two heavy chains and ...
 611-1619 3.09e-06

Myosin tail; The myosin molecule is a multi-subunit complex made up of two heavy chains and four light chains it is a fundamental contractile protein found in all eukaryote cell types. This family consists of the coiled-coil myosin heavy chain tail region. The coiled-coil is composed of the tail from two molecules of myosin. These can then assemble into the macromolecular thick filament. The coiled-coil region provides the structural backbone the thick filament.


Pssm-ID: 460256 [Multi-domain]  Cd Length: 1081  Bit Score: 52.48  E-value: 3.09e-06
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 861483604   611 KEKAAKLEILQQQLQAANEAQDSAQNSVTQAQREKAELSQKVEELHALIEAAHQEQCEAQTQvaaLEARLKAEQQKATEr 690
Cdd:pfam01576   18 KERQQKAESELKELEKKHQQLCEEKNALQEQLQAETELCAEAEEMRARLAARKQELEEILHE---LESRLEEEEERSQQ- 93

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 861483604   691 ekVAQEKAQLQEQLWSLEESLKITKGS---LEEEKCRAAAALEEHQHHISEMEAESRSLaeqhKQERKELEEEKAKrrgl 767
Cdd:pfam01576   94 --LQNEKKKMQQHIQDLEEQLDEEEAArqkLQLEKVTTEAKIKKLEEDILLLEDQNSKL----SKERKLLEERISE---- 163

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 861483604   768 gvqlqqlAETHQAETKALRQELAKARTSNNMAEREVEL-LVKEVKTWRKRYEDSQQGETQYG-LQEQLTTLKEEYEKSCQ 845
Cdd:pfam01576  164 -------FTSNLAEEEEKAKSLSKLKNKHEAMISDLEErLKKEEKGRQELEKAKRKLEGESTdLQEQIAELQAQIAELRA 236

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 861483604   846 ELRETKEKMAGIEAHSELQIGQH----------QSELAQLHANLARALQQVQEKENRAQKLADDLSTLQEKMAATSKEVA 915
Cdd:pfam01576  237 QLAKKEEELQAALARLEEETAQKnnalkkirelEAQISELQEDLESERAARNKAEKQRRDLGEELEALKTELEDTLDTTA 316

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 861483604   916 RLEALvRKAGEQQETASLELLKEPPKTRDRESEWVEEQQGQQLCSTQAALRamerEAEQMGTELEKLRAALMESQGQQQE 995
Cdd:pfam01576  317 AQQEL-RSKREQEVTELKKALEEETRSHEAQLQEMRQKHTQALEELTEQLE----QAKRNKANLEKAKQALESENAELQA 391

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 861483604   996 ERGQQEREVARLTQERGQAEADLAlEKAAKAELEMRLQNALNEQQAEFANLQEALSRALSEKEGKDQELSKLCEQEAVQR 1075
Cdd:pfam01576  392 ELRTLQQAKQDSEHKRKKLEGQLQ-ELQARLSESERQRAELAEKLSKLQSELESVSSLLNEAEGKNIKLSKDVSSLESQL 470

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 861483604  1076 MELKELLQTVEQLKAQLAKKekeqqqsARGASGENASGMGTQSEAVGKMEALRAKVSKLEQQCQQQQEEADSLARSLESE 1155
Cdd:pfam01576  471 QDTQELLQEETRQKLNLSTR-------LRQLEDERNSLQEQLEEEEEAKRNVERQLSTLQAQLSDMKKKLEEDAGTLEAL 543

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 861483604  1156 RAFHVERDRALETLQGQLEEKARELGYSQAASASAQRELATLRAKAQDHSKAEEEWKAQVARGQQEAVRKGSLISSLEEE 1235
Cdd:pfam01576  544 EEGKKRLQRELEALTQQLEEKAAAYDKLEKTKNRLQQELDDLLVDLDHQRQLVSNLEKKQKKFDQMLAEEKAISARYAEE 623

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 861483604  1236 VSILNRQVLEKEGESKELKRLVIAESEKSQKLEERLRLLQMET---------ASNSARAAERSS-ALREEVQSLR---EE 1302
Cdd:pfam01576  624 RDRAEAEAREKETRALSLARALEEALEAKEELERTNKQLRAEMedlvsskddVGKNVHELERSKrALEQQVEEMKtqlEE 703

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 861483604  1303 VEKQRAASEN--LRQELASQAERAEeLGQELKAWQEKFFQKEQALSA--------LQLEHTSTQALVSELLPAKHLCQQL 1372
Cdd:pfam01576  704 LEDELQATEDakLRLEVNMQALKAQ-FERDLQARDEQGEEKRRQLVKqvreleaeLEDERKQRAQAVAAKKKLELDLKEL 782

                          810       820       830       840       850       860       870       880
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 861483604  1373 QAEQVAAEKRHREELEQSKQaaggLRTELMRAQRELGELVPLRQKV----AEQERAAQQLRAEKASYAEQLSMLKKAHGL 1448
Cdd:pfam01576  783 EAQIDAANKGREEAVKQLKK----LQAQMKDLQRELEEARASRDEIlaqsKESEKKLKNLEAELLQLQEDLAASERARRQ 858

                          890       900       910       920       930       940       950       960
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 861483604  1449 LAEENRGLGERANLGRQFLEVELDQAREkyiqelaavrgdAETRLAEMRQEVQSTTHELEVMTAKYEGAKVKVLEERQRF 1528
Cdd:pfam01576  859 AQQERDELADEIASGASGKSALQDEKRR------------LEARIAQLEEELEEEQSNTELLNDRLRKSTLQVEQLTTEL 926

                          970       980       990      1000      1010      1020      1030      1040
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 861483604  1529 QEER---QKLTAQVEQLEVFQREQTKKVEELSKKL-ADYDQASKVQQQKLKAFQAQGGESQQEAQ-------RLQTQLNE 1597
Cdd:pfam01576  927 AAERstsQKSESARQQLERQNKELKAKLQEMEGTVkSKFKSSIAALEAKIAQLEEQLEQESRERQaanklvrRTEKKLKE 1006

                         1050      1060
                   ....*....|....*....|..
gi 861483604  1598 LQVQLSQKEQAAEHYKVQMEKA 1619
Cdd:pfam01576 1007 VLLQVEDERRHADQYKDQAEKG 1028
SMC_prok_A TIGR02169
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of ...
 1370-1689 3.17e-06

chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. It is found in a single copy and is homodimeric in prokaryotes, but six paralogs (excluded from this family) are found in eukarotes, where SMC proteins are heterodimeric. This family represents the SMC protein of archaea and a few bacteria (Aquifex, Synechocystis, etc); the SMC of other bacteria is described by TIGR02168. The N- and C-terminal domains of this protein are well conserved, but the central hinge region is skewed in composition and highly divergent. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274009 [Multi-domain]  Cd Length: 1164  Bit Score: 52.76  E-value: 3.17e-06
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 861483604  1370 QQLQAEQVAAEKRH--REELEQSKQAAGGLRTELMRAQRE--LGELVPLRQKVAEQERAAQQLRAEKASYAEQLSMLKKA 1445
Cdd:TIGR02169  201 ERLRREREKAERYQalLKEKREYEGYELLKEKEALERQKEaiERQLASLEEELEKLTEEISELEKRLEEIEQLLEELNKK 280

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 861483604  1446 hgllaEENRGLGERANLGRQFLEVELDQAREKYIQElaavrgDAETRLAEMRQEVQSTTHELEvmtaKYEGAKVKVLEER 1525
Cdd:TIGR02169  281 -----IKDLGEEEQLRVKEKIGELEAEIASLERSIA------EKERELEDAEERLAKLEAEID----KLLAEIEELEREI 345

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 861483604  1526 QRFQEERQKLTAQVEQLEVFQREQTKKVEELSKKLADYDQASKVQQQKLKAFQAQGGESQQEAQRLQTQLNELQVQLSQK 1605
Cdd:TIGR02169  346 EEERKRRDKLTEEYAELKEELEDLRAELEEVDKEFAETRDELKDYREKLEKLKREINELKRELDRLQEELQRLSEELADL 425

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 861483604  1606 EQAAEHYKVQMEKAKThydAKKQQNQELQEQLQGLEQLQKENKELRAEAERLGQELQQAGLKTKEAEQTCRHLTAQVRSL 1685
Cdd:TIGR02169  426 NAAIAGIEAKINELEE---EKEDKALEIKKQEWKLEQLAADLSKYEQELYDLKEEYDRVEKELSKLQRELAEAEAQARAS 502


                   ....
gi 861483604  1686 EAQV 1689
Cdd:TIGR02169  503 EERV 506
Mplasa_alph_rch TIGR04523
helix-rich Mycoplasma protein; Members of this family occur strictly within a subset of ...
 216-521 3.99e-06

helix-rich Mycoplasma protein; Members of this family occur strictly within a subset of Mycoplasma species. Members average 750 amino acids in length, including signal peptide. Sequences are predicted (Jpred 3) to be almost entirely alpha-helical. These sequences show strong periodicity (consistent with long alpha helical structures) and low complexity rich in D,E,N,Q, and K. Genes encoding these proteins are often found in tandem. The function is unknown.


Pssm-ID: 275316 [Multi-domain]  Cd Length: 745  Bit Score: 51.94  E-value: 3.99e-06
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 861483604   216 MRRLKKQLADERNNRDELELELAEHRKLLTEKDAQISMMQQRIDRLALLNEKQAasplepRELEELRGKNESLTFRLHET 295
Cdd:TIGR04523  309 NKELKSELKNQEKKLEEIQNQISQNNKIISQLNEQISQLKKELTNSESENSEKQ------RELEEKQNEIEKLKKENQSY 382

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 861483604   296 LKQCQDLKTEKGQMDRKINQLSEENGDLSFKLREFASNLQQLQGALNELTEEHSKATQQ---WVEKQAHLEKELSTALQD 372
Cdd:TIGR04523  383 KQEIKNLESQINDLESKIQNQEKLNQQKDEQIKKLQQEKELLEKEIERLKETIIKNNSEikdLTNQDSVKELIIKNLDNT 462

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 861483604   373 KKCLEEKNEILQGKLSQLEERLAQLPESPRQEKGEVLGDVLQLESLKQEAATLATNNTQLQARVEMLENEQGQKEAQLLG 452
Cdd:TIGR04523  463 RESLETQLKVLSRSINKIKQNLEQKQKELKSKEKELKKLNEEKKELEEKVKDLTKKISSLKEKIEKLESEKKEKESKISD 542

                          250       260       270       280       290       300       310
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 861483604   453 ERSHFEEEKQ-----QLASLITNLQSSISNLSQAKEELEQAS---QAQGAKLNAQVASLTAELTTLSATLQQQDQEL 521
Cdd:TIGR04523  543 LEDELNKDDFelkkeNLEKEIDEKNKEIEELKQTQKSLKKKQeekQELIDQKEKEKKDLIKEIEEKEKKISSLEKEL 619
SCP-1 pfam05483
Synaptonemal complex protein 1 (SCP-1); Synaptonemal complex protein 1 (SCP-1) is the major ...
 264-811 4.30e-06

Synaptonemal complex protein 1 (SCP-1); Synaptonemal complex protein 1 (SCP-1) is the major component of the transverse filaments of the synaptonemal complex. Synaptonemal complexes are structures that are formed between homologous chromosomes during meiotic prophase.


Pssm-ID: 114219 [Multi-domain]  Cd Length: 787  Bit Score: 52.03  E-value: 4.30e-06
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 861483604   264 LNEKQAASPLEPRELEELRGKNESLTFRLHETLKQCQDLKTEKGQMDRKINQLSEENGDLSFKLREFASNLQQLQGALNE 343
Cdd:pfam05483  235 INDKEKQVSLLLIQITEKENKMKDLTFLLEESRDKANQLEEKTKLQDENLKELIEKKDHLTKELEDIKMSLQRSMSTQKA 314

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 861483604   344 LTEEHSKATQQWVEKQAHLEKELSTALQDKKCLEEKNEILQGKLSQLEERLAQlpESPRQEKGE----VLGDVLQLESLK 419
Cdd:pfam05483  315 LEEDLQIATKTICQLTEEKEAQMEELNKAKAAHSFVVTEFEATTCSLEELLRT--EQQRLEKNEdqlkIITMELQKKSSE 392

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 861483604   420 QEAATLATNNTQLQarVEMLENEQGQKEaQLLGERSHFEeekqQLASLITNLQSSISNLSQAKEELEQASQAQGAKLNAQ 499
Cdd:pfam05483  393 LEEMTKFKNNKEVE--LEELKKILAEDE-KLLDEKKQFE----KIAEELKGKEQELIFLLQAREKEIHDLEIQLTAIKTS 465

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 861483604   500 VASLTAELTTLSATLQQQDQELAGLKQQAQKKQAQLAQSLQQQEQASQGLRHQVEQLSGSLKQKEKQLE--EAARELDAS 577
Cdd:pfam05483  466 EEHYLKEVEDLKTELEKEKLKNIELTAHCDKLLLENKELTQEASDMTLELKKHQEDIINCKKQEERMLKqiENLEEKEMN 545

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 861483604   578 RRDHAQQLATAAKAQETSLRerdaaCQQLEALEKEKAAKLEILQQQLQaaneaQDSAQNSVTQAQREKAELSQKVEELHA 657
Cdd:pfam05483  546 LRDELESVREEFIQKGDEVK-----CKLDKSEENARSIEYEVLKKEKQ-----MKILENKCNNLKKQIENKNKNIEELHQ 615

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 861483604   658 LIEAAHQEQCEAQTQVAALEARL-KAEQQKATEREKVAQEKAQLQEQLwsleESLKITKGSLEEEKCRAAAALEEH---- 732
Cdd:pfam05483  616 ENKALKKKGSAENKQLNAYEIKVnKLELELASAKQKFEEIIDNYQKEI----EDKKISEEKLLEEVEKAKAIADEAvklq 691

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 861483604   733 -------QHHISEMEAesrsLAEQHKQERKELEEEKAKRRGLGVQLQQLAETHQA----ETKALRQELAKARTSNNMAER 801
Cdd:pfam05483  692 keidkrcQHKIAEMVA----LMEKHKHQYDKIIEERDSELGLYKNKEQEQSSAKAaleiELSNIKAELLSLKKQLEIEKE 767

                          570
                   ....*....|
gi 861483604   802 EVELLVKEVK 811
Cdd:pfam05483  768 EKEKLKMEAK 777
Mplasa_alph_rch TIGR04523
helix-rich Mycoplasma protein; Members of this family occur strictly within a subset of ...
 388-937 4.85e-06

helix-rich Mycoplasma protein; Members of this family occur strictly within a subset of Mycoplasma species. Members average 750 amino acids in length, including signal peptide. Sequences are predicted (Jpred 3) to be almost entirely alpha-helical. These sequences show strong periodicity (consistent with long alpha helical structures) and low complexity rich in D,E,N,Q, and K. Genes encoding these proteins are often found in tandem. The function is unknown.


Pssm-ID: 275316 [Multi-domain]  Cd Length: 745  Bit Score: 51.94  E-value: 4.85e-06
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 861483604   388 SQLEERLAQLPESPRQEKGEVLGDVLQLESLKQEAATLATNNTQLQARVEMLENEQGQkeaqllgershFEEEKQQLASL 467
Cdd:TIGR04523  120 NKLEVELNKLEKQKKENKKNIDKFLTEIKKKEKELEKLNNKYNDLKKQKEELENELNL-----------LEKEKLNIQKN 188

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 861483604   468 ITNLQSSISNLSQAKEELEQASQAQgAKLNAQVASLTAELTTLSATLQQQDQELAGLKQQAQKKQAQLAQSLQQQEQASQ 547
Cdd:TIGR04523  189 IDKIKNKLLKLELLLSNLKKKIQKN-KSLESQISELKKQNNQLKDNIEKKQQEINEKTTEISNTQTQLNQLKDEQNKIKK 267

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 861483604   548 GLRH---QVEQLSGSLKQKEKQLEEAARELDASRRDHAQQLATAAKAQetslrerdaacqqlealEKEKAAKLEILQQQL 624
Cdd:TIGR04523  268 QLSEkqkELEQNNKKIKELEKQLNQLKSEISDLNNQKEQDWNKELKSE-----------------LKNQEKKLEEIQNQI 330

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 861483604   625 QAANEAQDSAQNSVTQAQREK-------AELSQKVEELHALIEAAHQEQCEAQTQVAALEARLKAEQQKATEREKVAQek 697
Cdd:TIGR04523  331 SQNNKIISQLNEQISQLKKELtnsesenSEKQRELEEKQNEIEKLKKENQSYKQEIKNLESQINDLESKIQNQEKLNQ-- 408

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 861483604   698 aQLQEQLwsleESLKITKGSLEEEkcraaaaLEEHQHHISEMEAESRSLAEQHKQERKELEEEKAKRRGLGVQLQQLA-- 775
Cdd:TIGR04523  409 -QKDEQI----KKLQQEKELLEKE-------IERLKETIIKNNSEIKDLTNQDSVKELIIKNLDNTRESLETQLKVLSrs 476

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 861483604   776 -ETHQAETKALRQELAKARTSNNMAEREVELLVKEVKTWRKRYEDSQQGetqyglQEQLTTLKEEYEKSCQELRETKEKM 854
Cdd:TIGR04523  477 iNKIKQNLEQKQKELKSKEKELKKLNEEKKELEEKVKDLTKKISSLKEK------IEKLESEKKEKESKISDLEDELNKD 550

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 861483604   855 AGIEAHSEL--QIGQHQSELAQLHANLARALQQVQEKENRAQKLADDLSTLQEKMAATSKEVARLEALVRKAGEQQETAS 932
Cdd:TIGR04523  551 DFELKKENLekEIDEKNKEIEELKQTQKSLKKKQEEKQELIDQKEKEKKDLIKEIEEKEKKISSLEKELEKAKKENEKLS 630


                   ....*
gi 861483604   933 LELLK 937
Cdd:TIGR04523  631 SIIKN 635
MukB COG3096
Chromosome condensin MukBEF, ATPase and DNA-binding subunit MukB [Cell cycle control, cell ...
 1276-1727 6.05e-06

Chromosome condensin MukBEF, ATPase and DNA-binding subunit MukB [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 442330 [Multi-domain]  Cd Length: 1470  Bit Score: 51.88  E-value: 6.05e-06
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 861483604 1276 METASNSARAAERSSALREEVQSLREEVEKQRAASENLRQELASQAERAEELGQELKAWQEKFFQKEQALsALQLEHTST 1355
Cdd:COG3096   274 MRHANERRELSERALELRRELFGARRQLAEEQYRLVEMARELEELSARESDLEQDYQAASDHLNLVQTAL-RQQEKIERY 352

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 861483604 1356 QALVSELlpAKHLCQQLQAEQVAAEKR--HREELEQSKQAAGGLRTELMRAQRELGELvplrqkvaeQERAAQqlraeka 1433
Cdd:COG3096   353 QEDLEEL--TERLEEQEEVVEEAAEQLaeAEARLEAAEEEVDSLKSQLADYQQALDVQ---------QTRAIQ------- 414

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 861483604 1434 sYAEQLSMLKKAHGLLAEenrglgerANLGRQFLEVELDQAREKyIQELAAVRGDAETRLAEMRQEVQSTTHELEVMTAK 1513
Cdd:COG3096   415 -YQQAVQALEKARALCGL--------PDLTPENAEDYLAAFRAK-EQQATEEVLELEQKLSVADAARRQFEKAYELVCKI 484

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 861483604 1514 YEGakvkvLEERQRFQEERQKLTAQVEQLEVFQREQTkkveeLSKKLADYDQASkvqqqklkafqaqggESQQEAQRLQT 1593
Cdd:COG3096   485 AGE-----VERSQAWQTARELLRRYRSQQALAQRLQQ-----LRAQLAELEQRL---------------RQQQNAERLLE 539

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 861483604 1594 QLNE-LQVQLSQKEQAAEHYKVQMEKAKTHYDAKKQQNQELQEQLQGLEQLQKENKELRAEAERLgQELQQAglktkeAE 1672
Cdd:COG3096   540 EFCQrIGQQLDAAEELEELLAELEAQLEELEEQAAEAVEQRSELRQQLEQLRARIKELAARAPAW-LAAQDA------LE 612

                         410       420       430       440       450
                  ....*....|....*....|....*....|....*....|....*....|....*
gi 861483604 1673 QTCRHLTAQVRSLEAQVAHADQQLRELGKFQVASDALKsrepQAKPQLDLSIDSL 1727
Cdd:COG3096   613 RLREQSGEALADSQEVTAAMQQLLEREREATVERDELA----ARKQALESQIERL 663
CCDC158 pfam15921
Coiled-coil domain-containing protein 158; CCDC158 is a family of proteins found in eukaryotes. ...
 729-1480 6.11e-06

Coiled-coil domain-containing protein 158; CCDC158 is a family of proteins found in eukaryotes. The function is not known.


Pssm-ID: 464943 [Multi-domain]  Cd Length: 1112  Bit Score: 51.66  E-value: 6.11e-06
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 861483604   729 LEEHQHHISEMEAESRSLAEQHkqerkelEEEKAKRRGLGVQLQQLAETHQAETKALRQELAKARTSNNMAEREVELLVK 808
Cdd:pfam15921   80 LEEYSHQVKDLQRRLNESNELH-------EKQKFYLRQSVIDLQTKLQEMQMERDAMADIRRRESQSQEDLRNQLQNTVH 152

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 861483604   809 EVKTWRKRYEDS-QQGETQYglqEQLTTLKEEYEKSCQELRETkekMAGIEAHSELQIGQHQSELAQLHANLARALQQV- 886
Cdd:pfam15921  153 ELEAAKCLKEDMlEDSNTQI---EQLRKMMLSHEGVLQEIRSI---LVDFEEASGKKIYEHDSMSTMHFRSLGSAISKIl 226

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 861483604   887 QEKENRAQKLADDLSTLQEKMAATSKEVA-RLEALVRKAGEQQETASLE-------LLKEPPKTRDRES------EWVEE 952
Cdd:pfam15921  227 RELDTEISYLKGRIFPVEDQLEALKSESQnKIELLLQQHQDRIEQLISEheveitgLTEKASSARSQANsiqsqlEIIQE 306

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 861483604   953 QQGQQLCSTQAALRAMEREAEQMGTELEKLRAALMESQGQQQEERGQQEREVARLTQERGQaeadLALEKAAKAELEMRL 1032
Cdd:pfam15921  307 QARNQNSMYMRQLSDLESTVSQLRSELREAKRMYEDKIEELEKQLVLANSELTEARTERDQ----FSQESGNLDDQLQKL 382

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 861483604  1033 QNALNEQQAEFANLQEALSRALSEKEGKDQELSKLCEQEAVQRMELKELLQTVEQLKAQlAKKEKEQQQSArgASGENAS 1112
Cdd:pfam15921  383 LADLHKREKELSLEKEQNKRLWDRDTGNSITIDHLRRELDDRNMEVQRLEALLKAMKSE-CQGQMERQMAA--IQGKNES 459

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 861483604  1113 gMGTQSEAVGKMEALRAKVSKLEQQCQQQQEEADSLARSLESERAFHVERDRALET-------LQGQLEEKARELGYSQA 1185
Cdd:pfam15921  460 -LEKVSSLTAQLESTKEMLRKVVEELTAKKMTLESSERTVSDLTASLQEKERAIEAtnaeitkLRSRVDLKLQELQHLKN 538

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 861483604  1186 AS---ASAQRELATLRAKAQDHSKAEEEWKAQVARGQQEAVRKGSLISSLEEEVSILNRQVLEKEGESKELKRLVIAESE 1262
Cdd:pfam15921  539 EGdhlRNVQTECEALKLQMAEKDKVIEILRQQIENMTQLVGQHGRTAGAMQVEKAQLEKEINDRRLELQEFKILKDKKDA 618

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 861483604  1263 KSQKLEERLRLLQMETASNSARAAERSSALREevqsLREEVEKQRAASENLRQELASQAERAEELGQELKAWQEKFfqkE 1342
Cdd:pfam15921  619 KIRELEARVSDLELEKVKLVNAGSERLRAVKD----IKQERDQLLNEVKTSRNELNSLSEDYEVLKRNFRNKSEEM---E 691

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 861483604  1343 QALSALQLEHTSTQalvSELLPAKHLCQQLQAEQVAAEKrhreeleqskqAAGGLRTELMrAQRelGELVPLRQKVAEQE 1422
Cdd:pfam15921  692 TTTNKLKMQLKSAQ---SELEQTRNTLKSMEGSDGHAMK-----------VAMGMQKQIT-AKR--GQIDALQSKIQFLE 754

                          730       740       750       760       770       780
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 861483604  1423 RAAQQLRAEKASYAEQLSMLKKAHGLLA-EENRGLGERANLGRQ---------FLEVELDQAREKYIQ 1480
Cdd:pfam15921  755 EAMTNANKEKHFLKEEKNKLSQELSTVAtEKNKMAGELEVLRSQerrlkekvaNMEVALDKASLQFAE 822
EnvC COG4942
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, ...
 378-602 6.37e-06

Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 443969 [Multi-domain]  Cd Length: 377  Bit Score: 50.92  E-value: 6.37e-06
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 861483604  378 EKNEILQGKLSQLEERLAQLPESPRQEKGEVLGDVLQLESLKQEAATLATNNTQLQARVEMLENEQGQKEAQLLGERSHF 457
Cdd:COG4942    20 DAAAEAEAELEQLQQEIAELEKELAALKKEEKALLKQLAALERRIAALARRIRALEQELAALEAELAELEKEIAELRAEL 99

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 861483604  458 EEEKQQLASLITNLQSSiSNLSQAKEELEQASQAQGAKLNAQVASLTAELTTLSATLQQQDQELAGLKQQAQKKQAQLAQ 537
Cdd:COG4942   100 EAQKEELAELLRALYRL-GRQPPLALLLSPEDFLDAVRRLQYLKYLAPARREQAEELRADLAELAALRAELEAERAELEA 178

                         170       180       190       200       210       220
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 861483604  538 SLQQQEQASQGL---RHQVEQLSGSLKQKEKQLEEAARELDASRRDHAQQLATAAKAQETSLRERDAA 602
Cdd:COG4942   179 LLAELEEERAALealKAERQKLLARLEKELAELAAELAELQQEAEELEALIARLEAEAAAAAERTPAA 246
PRK10929 PRK10929
putative mechanosensitive channel protein; Provisional
 1152-1408 7.93e-06

putative mechanosensitive channel protein; Provisional


Pssm-ID: 236798 [Multi-domain]  Cd Length: 1109  Bit Score: 51.21  E-value: 7.93e-06
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 861483604 1152 LESERAFHVERDRA------LETLQGQLEEKARELgysqaasASAQRELATLRAKAQDHSKAeeewkaQVARGQQEAVRK 1225
Cdd:PRK10929  119 LEKSRQAQQEQDRAreisdsLSQLPQQQTEARRQL-------NEIERRLQTLGTPNTPLAQA------QLTALQAESAAL 185

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 861483604 1226 GSLISSLE-EEVSILNRQvlekegeskELKRLviaESEKSQKLEERL--RLLQMETASNSAR------AAERSSALREEV 1296
Cdd:PRK10929  186 KALVDELElAQLSANNRQ---------ELARL---RSELAKKRSQQLdaYLQALRNQLNSQRqreaerALESTELLAEQS 253

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 861483604 1297 QSLREEVEKQRAASENLRQELASQAERAEELGQELKAWQEKFFQKEQALSAL----QLEHTST---QALVSEL--LPAKH 1367
Cdd:PRK10929  254 GDLPKSIVAQFKINRELSQALNQQAQRMDLIASQQRQAASQTLQVRQALNTLreqsQWLGVSNalgEALRAQVarLPEMP 333

                         250       260       270       280       290
                  ....*....|....*....|....*....|....*....|....*....|....*...
gi 861483604 1368 LCQQLQAE--QVAAEKRHREEL-------EQSKQAAGGLRT--------ELMRAQREL 1408
Cdd:PRK10929  334 KPQQLDTEmaQLRVQRLRYEDLlnkqpqlRQIRQADGQPLTaeqnrildAQLRTQREL 391
PRK03918 PRK03918
DNA double-strand break repair ATPase Rad50;
635-1320 1.16e-05

DNA double-strand break repair ATPase Rad50;


Pssm-ID: 235175 [Multi-domain]  Cd Length: 880  Bit Score: 50.83  E-value: 1.16e-05
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 861483604  635 QNSVTQAQREKAELSQKVEELHALIEAAHQEQCEAQTQVAALEARLKAEQQKATEREKVAQEKAQLQEQLWSLEESLKIT 714
Cdd:PRK03918  192 EELIKEKEKELEEVLREINEISSELPELREELEKLEKEVKELEELKEEIEELEKELESLEGSKRKLEEKIRELEERIEEL 271

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 861483604  715 KGSLEEekcraaaaLEEHQHHISEMEAEsrslAEQHKQERKELEEEKAKRRGLGVQLQQLAEthqaETKALRQELAKArt 794
Cdd:PRK03918  272 KKEIEE--------LEEKVKELKELKEK----AEEYIKLSEFYEEYLDELREIEKRLSRLEE----EINGIEERIKEL-- 333

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 861483604  795 snNMAEREVELLVKEVKTWRKRYedsqqgetqyglqeqlttlkEEYEKSCQELRETKEKMAGIEahselqigQHQSELAQ 874
Cdd:PRK03918  334 --EEKEERLEELKKKLKELEKRL--------------------EELEERHELYEEAKAKKEELE--------RLKKRLTG 383

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 861483604  875 LhaNLARALQQVQEKENRAQKLADDLSTLQEKMAATSKEVARLealvrkageqqETASLELLKEPPKTRDRESEWVEEQQ 954
Cdd:PRK03918  384 L--TPEKLEKELEELEKAKEEIEEEISKITARIGELKKEIKEL-----------KKAIEELKKAKGKCPVCGRELTEEHR 450

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 861483604  955 GQQLCSTQAALRAMEREAEQMGTELEKLRAALMESQGQQQEERgqqerevaRLTQERGQAEADLALEKaakaELEMRLQN 1034
Cdd:PRK03918  451 KELLEEYTAELKRIEKELKEIEEKERKLRKELRELEKVLKKES--------ELIKLKELAEQLKELEE----KLKKYNLE 518

                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 861483604 1035 ALNEQQAEFANLQEALSRALSEKEGKDQELSKLCEQEAvqrmELKELLQTVEQLKAQLAKKEKEQQQSARGASGENASGM 1114
Cdd:PRK03918  519 ELEKKAEEYEKLKEKLIKLKGEIKSLKKELEKLEELKK----KLAELEKKLDELEEELAELLKELEELGFESVEELEERL 594

                         490       500       510       520       530       540       550       560
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 861483604 1115 GTQSEAVGKMEALRAKVSKLEQQCQQQqeeaDSLARSLESERAFHVERDRALETLQGQLEEKARElgYSQaasasaqrel 1194
Cdd:PRK03918  595 KELEPFYNEYLELKDAEKELEREEKEL----KKLEEELDKAFEELAETEKRLEELRKELEELEKK--YSE---------- 658

                         570       580       590       600       610       620       630       640
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 861483604 1195 atlrakaQDHSKAEEEWkaqvargqqeaVRKGSLISSLEEEVSILNRQVLEKEGESKELKRlviaESEKSQKLEERLRLL 1274
Cdd:PRK03918  659 -------EEYEELREEY-----------LELSRELAGLRAELEELEKRREEIKKTLEKLKE----ELEEREKAKKELEKL 716

                         650       660       670       680
                  ....*....|....*....|....*....|....*....|....*.
gi 861483604 1275 QmetasnsaRAAERSSALREEVQSLREEVeKQRAASEnlRQELASQ 1320
Cdd:PRK03918  717 E--------KALERVEELREKVKKYKALL-KERALSK--VGEIASE 751
SMC_prok_B TIGR02168
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...
 213-488 1.25e-05

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274008 [Multi-domain]  Cd Length: 1179  Bit Score: 50.83  E-value: 1.25e-05
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 861483604   213 QFQMRRLKKQLADERNNRDELELELAEHRKLLTEKDAQISMMQQRIDRL-ALLNEKQAASPLEPRELEELRGKNESLTFR 291
Cdd:TIGR02168  753 SKELTELEAEIEELEERLEEAEEELAEAEAEIEELEAQIEQLKEELKALrEALDELRAELTLLNEEAANLRERLESLERR 832

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 861483604   292 LHETLKQCQDLKTEKGQMDRKINQLSEENGDLSFKLREFASNLQQLQ---GALNELTEEHSKATQQWVEKQAHLEKELST 368
Cdd:TIGR02168  833 IAATERRLEDLEEQIEELSEDIESLAAEIEELEELIEELESELEALLnerASLEEALALLRSELEELSEELRELESKRSE 912

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 861483604   369 ALQDKKCLEEKNEILQGKLSQLEERLAQLPESPRQEKGEVLGDVLQLESLKQEAAtlatnnTQLQARVEMLENEQGQKEA 448
Cdd:TIGR02168  913 LRRELEELREKLAQLELRLEGLEVRIDNLQERLSEEYSLTLEEAEALENKIEDDE------EEARRRLKRLENKIKELGP 986

                          250       260       270       280
                   ....*....|....*....|....*....|....*....|
gi 861483604   449 QLLGERSHFEEEKQQLasliTNLQSSISNLSQAKEELEQA 488
Cdd:TIGR02168  987 VNLAAIEEYEELKERY----DFLTAQKEDLTEAKETLEEA 1022
MAD pfam05557
Mitotic checkpoint protein; This family consists of several eukaryotic mitotic checkpoint ...
 1241-1660 1.44e-05

Mitotic checkpoint protein; This family consists of several eukaryotic mitotic checkpoint (Mitotic arrest deficient or MAD) proteins. The mitotic spindle checkpoint monitors proper attachment of the bipolar spindle to the kinetochores of aligned sister chromatids and causes a cell cycle arrest in prometaphase when failures occur. Multiple components of the mitotic spindle checkpoint have been identified in yeast and higher eukaryotes. In S.cerevisiae, the existence of a Mad1-dependent complex containing Mad2, Mad3, Bub3 and Cdc20 has been demonstrated.


Pssm-ID: 461677 [Multi-domain]  Cd Length: 660  Bit Score: 50.12  E-value: 1.44e-05
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 861483604  1241 RQVLEKEGESKELKRLVIAESEKSQKLEERLRLLQmetasnsARAAERSSALREEVQSLREEVEKQRAASENLRQELASQ 1320
Cdd:pfam05557   27 RARIELEKKASALKRQLDRESDRNQELQKRIRLLE-------KREAEAEEALREQAELNRLKKKYLEALNKKLNEKESQL 99

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 861483604  1321 AERAE---ELGQELKAWQEKFFQKEQALSALQLEHTSTQALVSEL----LPAKHLCQQLQAEQ---VAAEKRHRE-ELEQ 1389
Cdd:pfam05557  100 ADAREvisCLKNELSELRRQIQRAELELQSTNSELEELQERLDLLkakaSEAEQLRQNLEKQQsslAEAEQRIKElEFEI 179

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 861483604  1390 SKQAAGGLRTELMRAQRElgelvplrqKVAEQERAAQQLRAEKasyaEQLSMLKKAHGLLAEENRGLgeRANLGRQflev 1469
Cdd:pfam05557  180 QSQEQDSEIVKNSKSELA---------RIPELEKELERLREHN----KHLNENIENKLLLKEEVEDL--KRKLERE---- 240

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 861483604  1470 eldqarEKYIQELAAVRGDAETRLAEMRQEVQ-STTHELEVMTAKYEGAKVKVLEERQR-FQEERQKLTAQVEQLEVFQR 1547
Cdd:pfam05557  241 ------EKYREEAATLELEKEKLEQELQSWVKlAQDTGLNLRSPEDLSRRIEQLQQREIvLKEENSSLTSSARQLEKARR 314

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 861483604  1548 E-------QTKKVEELSKKLADYD-QASKVQQQKLKAFQAQGG--------------------------ESQQEAQRLQT 1593
Cdd:pfam05557  315 EleqelaqYLKKIEDLNKKLKRHKaLVRRLQRRVLLLTKERDGyrailesydkeltmsnyspqllerieEAEDMTQKMQA 394

                          410       420       430       440       450       460
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 861483604  1594 QLNELQVQLSQKEQAAEHYKVQMEKAKTHYDAKKQQNQEL--QEQLQGLEQLQKENKELRAEAERLGQE 1660
Cdd:pfam05557  395 HNEEMEAQLSVAEEELGGYKQQAQTLERELQALRQQESLAdpSYSKEEVDSLRRKLETLELERQRLREQ 463
PRK03918 PRK03918
DNA double-strand break repair ATPase Rad50;
276-932 1.76e-05

DNA double-strand break repair ATPase Rad50;


Pssm-ID: 235175 [Multi-domain]  Cd Length: 880  Bit Score: 50.06  E-value: 1.76e-05
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 861483604  276 RELEELRGKNESLTFRLHETLKQCQDLKTEKGQMDRKINQLSEENGDLSFKLREFASNLQQLQGALNELTEehskatqqw 355
Cdd:PRK03918  172 KEIKRRIERLEKFIKRTENIEELIKEKEKELEEVLREINEISSELPELREELEKLEKEVKELEELKEEIEE--------- 242

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 861483604  356 vekqahLEKELSTALQDKKCLEEKNEILQGKLSQLEERLAQLpESPRQEKGEVLGDVLQLESLKQEAATLATNNTQLQAR 435
Cdd:PRK03918  243 ------LEKELESLEGSKRKLEEKIRELEERIEELKKEIEEL-EEKVKELKELKEKAEEYIKLSEFYEEYLDELREIEKR 315

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 861483604  436 VEMLENEQGQKEAQlLGERSHFEEEKQQLASLITNLQSSISNLSQAKEELEQASQaqgakLNAQVASLTAELTTLSATLQ 515
Cdd:PRK03918  316 LSRLEEEINGIEER-IKELEEKEERLEELKKKLKELEKRLEELEERHELYEEAKA-----KKEELERLKKRLTGLTPEKL 389

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 861483604  516 QQDQELAGLKQQAQKKQaqlaqslqqqeqasqglRHQVEQLSGSLKQKEKQLEEAARELDASRR-----------DHAQQ 584
Cdd:PRK03918  390 EKELEELEKAKEEIEEE-----------------ISKITARIGELKKEIKELKKAIEELKKAKGkcpvcgrelteEHRKE 452

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 861483604  585 LATAAKAQETSLRERDAacqqlEALEKEKAAKLEILQQQLQAANEAQDSAQNSVTQAQREKAELSQK--VEELhaliEAA 662
Cdd:PRK03918  453 LLEEYTAELKRIEKELK-----EIEEKERKLRKELRELEKVLKKESELIKLKELAEQLKELEEKLKKynLEEL----EKK 523

                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 861483604  663 HQEQCEAQTQVAALEARLKAEQQKATEREKVAQEKAQLQEQLWSLEESLKITKGSLEEekcRAAAALEEHQHHISEMEAE 742
Cdd:PRK03918  524 AEEYEKLKEKLIKLKGEIKSLKKELEKLEELKKKLAELEKKLDELEEELAELLKELEE---LGFESVEELEERLKELEPF 600

                         490       500       510       520       530       540       550       560
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 861483604  743 SRSLAEQhKQERKELEEEKAKRrglgvqlqqlaethqaetKALRQELAKARTSNNMAEREVELLVKEVKTWRKRYEDsqq 822
Cdd:PRK03918  601 YNEYLEL-KDAEKELEREEKEL------------------KKLEEELDKAFEELAETEKRLEELRKELEELEKKYSE--- 658

                         570       580       590       600       610       620       630       640
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 861483604  823 getqyglqeqlttlkEEYEKSCQELRETKEKMAGIEAHSElQIGQHQSELAQLHANLARALQQVQEKENRAQKLADDLST 902
Cdd:PRK03918  659 ---------------EEYEELREEYLELSRELAGLRAELE-ELEKRREEIKKTLEKLKEELEEREKAKKELEKLEKALER 722

                         650       660       670
                  ....*....|....*....|....*....|..
gi 861483604  903 LQEkmaaTSKEVARLEALVRKAG--EQQETAS 932
Cdd:PRK03918  723 VEE----LREKVKKYKALLKERAlsKVGEIAS 750
SCP-1 pfam05483
Synaptonemal complex protein 1 (SCP-1); Synaptonemal complex protein 1 (SCP-1) is the major ...
 1229-1699 1.98e-05

Synaptonemal complex protein 1 (SCP-1); Synaptonemal complex protein 1 (SCP-1) is the major component of the transverse filaments of the synaptonemal complex. Synaptonemal complexes are structures that are formed between homologous chromosomes during meiotic prophase.


Pssm-ID: 114219 [Multi-domain]  Cd Length: 787  Bit Score: 49.72  E-value: 1.98e-05
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 861483604  1229 ISSLEEEVSILNRQVLEKEGESKELKRLVIAESEKSQKLEERLRLlqmeTASNSARAAERSSALREEVQSLREEVEKQRA 1308
Cdd:pfam05483  235 INDKEKQVSLLLIQITEKENKMKDLTFLLEESRDKANQLEEKTKL----QDENLKELIEKKDHLTKELEDIKMSLQRSMS 310

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 861483604  1309 ASENLRQELASQAERAEELGQELKAWQEKFFQKEQALSALQLEHTSTQALVSELLpakhlcqqlqaeqvaaeKRHREELE 1388
Cdd:pfam05483  311 TQKALEEDLQIATKTICQLTEEKEAQMEELNKAKAAHSFVVTEFEATTCSLEELL-----------------RTEQQRLE 373

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 861483604  1389 QSKQAAGGLRTELMRAQRELGELVPLRQKVAEQERAAQQLRAEKasyaEQLSMLKKAHGLLAEENRGLGERAnlgrqfle 1468
Cdd:pfam05483  374 KNEDQLKIITMELQKKSSELEEMTKFKNNKEVELEELKKILAED----EKLLDEKKQFEKIAEELKGKEQEL-------- 441

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 861483604  1469 VELDQAREKYIQELaavrgdaETRLAEMRQEVQSTTHELEVMTAKYEGAKVKVLEerqrfqeerqkLTAQVEQLEVFQRE 1548
Cdd:pfam05483  442 IFLLQAREKEIHDL-------EIQLTAIKTSEEHYLKEVEDLKTELEKEKLKNIE-----------LTAHCDKLLLENKE 503

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 861483604  1549 QTKK----VEELSKKLADYDQASKVQQQKLKAFqaqggesqQEAQRLQTQL-NELQVQLSQKEQAAEHYKVQMEKAKTHY 1623
Cdd:pfam05483  504 LTQEasdmTLELKKHQEDIINCKKQEERMLKQI--------ENLEEKEMNLrDELESVREEFIQKGDEVKCKLDKSEENA 575

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 861483604  1624 DAKKQQNQELQEQLQGLEQ----LQKENKELRAEAERLGQELQQAGLKTKEAEQTCRHLTAQVRSLEAQVAHADQQLREL 1699
Cdd:pfam05483  576 RSIEYEVLKKEKQMKILENkcnnLKKQIENKNKNIEELHQENKALKKKGSAENKQLNAYEIKVNKLELELASAKQKFEEI 655
EnvC COG4942
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, ...
 1523-1728 2.54e-05

Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 443969 [Multi-domain]  Cd Length: 377  Bit Score: 48.99  E-value: 2.54e-05
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 861483604 1523 EERQRFQEERQKLTAQVEQLEVFQREQTKKVEELSKKLADYDQASKVQQQKLKAFQAQGGESQQEAQRLQTQLNELQVQL 1602
Cdd:COG4942    20 DAAAEAEAELEQLQQEIAELEKELAALKKEEKALLKQLAALERRIAALARRIRALEQELAALEAELAELEKEIAELRAEL 99

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 861483604 1603 -SQKEQAAEHYKVQMEKAKTHYDAKKQQNQELQEQLQGLEQLQKENKELRAEAERLGQELQQAGLKTKEAEQTCRHLTAQ 1681
Cdd:COG4942   100 eAQKEELAELLRALYRLGRQPPLALLLSPEDFLDAVRRLQYLKYLAPARREQAEELRADLAELAALRAELEAERAELEAL 179

                         170       180       190       200
                  ....*....|....*....|....*....|....*....|....*..
gi 861483604 1682 VRSLEAQVAHADQQLRELGKFQVASDALKSREPQAKPQLDLSIDSLD 1728
Cdd:COG4942   180 LAELEEERAALEALKAERQKLLARLEKELAELAAELAELQQEAEELE 226
EnvC COG4942
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, ...
 269-493 3.07e-05

Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 443969 [Multi-domain]  Cd Length: 377  Bit Score: 48.61  E-value: 3.07e-05
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 861483604  269 AASPLEPRELEELRGKNESLTFRLHETLKQCQDLKTEKGQMDRKINQLSEENGDLSFKLREFASNLQQLQGALNELTEEH 348
Cdd:COG4942    13 LAAAAQADAAAEAEAELEQLQQEIAELEKELAALKKEEKALLKQLAALERRIAALARRIRALEQELAALEAELAELEKEI 92

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 861483604  349 SKATQQWVEKQAHLEKELStALQDKKCLEEKNEILQGK-----------LSQLEERLAQLPESPRQEKGEVLGDVLQLES 417
Cdd:COG4942    93 AELRAELEAQKEELAELLR-ALYRLGRQPPLALLLSPEdfldavrrlqyLKYLAPARREQAEELRADLAELAALRAELEA 171

                         170       180       190       200       210       220       230
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 861483604  418 LKQEAATLATNNTQLQARVEMLENEQGQKEAQLLGERSHFEEEKQQLASLITNLQSSISNLSQAKEELEQASQAQG 493
Cdd:COG4942   172 ERAELEALLAELEEERAALEALKAERQKLLARLEKELAELAAELAELQQEAEELEALIARLEAEAAAAAERTPAAG 247
SMC_prok_B TIGR02168
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...
 1523-1728 3.17e-05

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274008 [Multi-domain]  Cd Length: 1179  Bit Score: 49.28  E-value: 3.17e-05
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 861483604  1523 EERQRFQEERQKLTAQVEQLEVFQREQTKKVEELSKKLADYDQASKVQQQKLKAFQAQGGESQQEAQRLQTQLNELQVQL 1602
Cdd:TIGR02168  239 EELEELQEELKEAEEELEELTAELQELEEKLEELRLEVSELEEEIEELQKELYALANEISRLEQQKQILRERLANLERQL 318

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 861483604  1603 SQKEQAAEHYKVQMEKAKTHYDAKKQQNQELQEQLQGLEQLQKENKELRAEAERLGQELQQAGL----KTKEAEQTCRHL 1678
Cdd:TIGR02168  319 EELEAQLEELESKLDELAEELAELEEKLEELKEELESLEAELEELEAELEELESRLEELEEQLEtlrsKVAQLELQIASL 398

                          170       180       190       200       210
                   ....*....|....*....|....*....|....*....|....*....|
gi 861483604  1679 TAQVRSLEAQVAHADQQLRELGkfQVASDALKSREPQAKPQLDLSIDSLD 1728
Cdd:TIGR02168  399 NNEIERLEARLERLEDRRERLQ--QEIEELLKKLEEAELKELQAELEELE 446
EnvC COG4942
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, ...
 556-793 3.24e-05

Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 443969 [Multi-domain]  Cd Length: 377  Bit Score: 48.61  E-value: 3.24e-05
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 861483604  556 LSGSLKQKEKQLEEAARELDASRrdhaQQLATAAKAQETSLRERDAACQQLEALEKekaaKLEILQQQLQAANEAQDSAQ 635
Cdd:COG4942    11 LALAAAAQADAAAEAEAELEQLQ----QEIAELEKELAALKKEEKALLKQLAALER----RIAALARRIRALEQELAALE 82

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 861483604  636 NSVTQAQREKAELSQKVEELHALIEAAHQEQcEAQTQVAALEARLKAEQQKATER-----EKVAQEKAQLQEQLWSLEES 710
Cdd:COG4942    83 AELAELEKEIAELRAELEAQKEELAELLRAL-YRLGRQPPLALLLSPEDFLDAVRrlqylKYLAPARREQAEELRADLAE 161

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 861483604  711 LKITKGSLEEEKCRAAAALEEHQHHISEMEAEsrslAEQHKQERKELEEEKAKRRGLGVQLQQLAETHQAETKALRQELA 790
Cdd:COG4942   162 LAALRAELEAERAELEALLAELEEERAALEAL----KAERQKLLARLEKELAELAAELAELQQEAEELEALIARLEAEAA 237


                  ...
gi 861483604  791 KAR 793
Cdd:COG4942   238 AAA 240
Smc COG1196
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ...
 1535-1699 3.51e-05

Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 440809 [Multi-domain]  Cd Length: 983  Bit Score: 49.16  E-value: 3.51e-05
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 861483604 1535 LTAQVEQLEVfQREQTKKVEELSKKLADYDQASKVQqqKLKAFQAQGGESQQEAQRLQTQLNELQVQLSQKEQAAEHYKV 1614
Cdd:COG1196   198 LERQLEPLER-QAEKAERYRELKEELKELEAELLLL--KLRELEAELEELEAELEELEAELEELEAELAELEAELEELRL 274

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 861483604 1615 QMEKAKTHYDAKKQQNQELQEQLQGLEQLQKENKEL---------RAEAERLGQELQQAGLKTK--EAEQTCRHLTAQVR 1683
Cdd:COG1196   275 ELEELELELEEAQAEEYELLAELARLEQDIARLEERrreleerleELEEELAELEEELEELEEEleELEEELEEAEEELE 354

                         170
                  ....*....|....*.
gi 861483604 1684 SLEAQVAHADQQLREL 1699
Cdd:COG1196   355 EAEAELAEAEEALLEA 370
YhaN COG4717
Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown];
1249-1690 4.60e-05

Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown];


Pssm-ID: 443752 [Multi-domain]  Cd Length: 641  Bit Score: 48.61  E-value: 4.60e-05
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 861483604 1249 ESKELKRLVIAESEKSQKLEERLRLLQmETASNSARAAERSSALREEVQSLREEVEKQRAASE--NLRQELASQAERAEE 1326
Cdd:COG4717    72 ELKELEEELKEAEEKEEEYAELQEELE-ELEEELEELEAELEELREELEKLEKLLQLLPLYQEleALEAELAELPERLEE 150

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 861483604 1327 LGQELKAWQEKFFQKEQALSALQLEHTSTQALVSELLPAKHLCQQLQAEQVaaeKRHREELEQSKQAAGGLRTELMRAQR 1406
Cdd:COG4717   151 LEERLEELRELEEELEELEAELAELQEELEELLEQLSLATEEELQDLAEEL---EELQQRLAELEEELEEAQEELEELEE 227

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 861483604 1407 ELGELVPLRQKVAEQERAaQQLRAEKASYAEQLSMLKKAHGLLAEENRGLG-ERANLGRQFLEVELDQAREKYIQELAAV 1485
Cdd:COG4717   228 ELEQLENELEAAALEERL-KEARLLLLIAAALLALLGLGGSLLSLILTIAGvLFLVLGLLALLFLLLAREKASLGKEAEE 306

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 861483604 1486 RGDAETRLAEMRQEVQSTTHELEVMTAKYEGAKVKVLEERQRFQEERQKLTAQVEQLEVFQREQtkkveELSKKLADYDQ 1565
Cdd:COG4717   307 LQALPALEELEEEELEELLAALGLPPDLSPEELLELLDRIEELQELLREAEELEEELQLEELEQ-----EIAALLAEAGV 381

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 861483604 1566 ASkvqqqkLKAFQAQGgESQQEAQRLQTQLNELQVQLSQKEQAAEHYKVQMEKAKTHYDAKKQQNQelqeqlqgLEQLQK 1645
Cdd:COG4717   382 ED------EEELRAAL-EQAEEYQELKEELEELEEQLEELLGELEELLEALDEEELEEELEELEEE--------LEELEE 446

                         410       420       430       440
                  ....*....|....*....|....*....|....*....|....*..
gi 861483604 1646 ENKELRAEAERLGQELQQAGLKTK--EAEQTCRHLTAQVRSLEAQVA 1690
Cdd:COG4717   447 ELEELREELAELEAELEQLEEDGElaELLQELEELKAELRELAEEWA 493
sbcc TIGR00618
exonuclease SbcC; All proteins in this family for which functions are known are part of an ...
 211-655 5.15e-05

exonuclease SbcC; All proteins in this family for which functions are known are part of an exonuclease complex with sbcD homologs. This complex is involved in the initiation of recombination to regulate the levels of palindromic sequences in DNA. This family is based on the phylogenomic analysis of JA Eisen (1999, Ph.D. Thesis, Stanford University). [DNA metabolism, DNA replication, recombination, and repair]


Pssm-ID: 129705 [Multi-domain]  Cd Length: 1042  Bit Score: 48.43  E-value: 5.15e-05
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 861483604   211 TPQFQMRRLKKQLADERNNRDELELELAEHRKLLTEKDAQI-SMMQQRIDRLALLNEKQAASPLEPRELEELRGKNESLT 289
Cdd:TIGR00618  448 TCTAQCEKLEKIHLQESAQSLKEREQQLQTKEQIHLQETRKkAVVLARLLELQEEPCPLCGSCIHPNPARQDIDNPGPLT 527

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 861483604   290 FRLHETLKQCQDLKTEKGQMDRKINQLSEENGDLSFKLREFASNLQQLQGALNELTEEHSKATQQWVEKQAHLEKELSTA 369
Cdd:TIGR00618  528 RRMQRGEQTYAQLETSEEDVYHQLTSERKQRASLKEQMQEIQQSFSILTQCDNRSKEDIPNLQNITVRLQDLTEKLSEAE 607

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 861483604   370 LQDKKCLEEKNEILQGKLSQLEERLAQLPESPRQEKGEVLGDVLQLESLKQEAATLATNNTQLQARVEMLENEQGQKEAQ 449
Cdd:TIGR00618  608 DMLACEQHALLRKLQPEQDLQDVRLHLQQCSQELALKLTALHALQLTLTQERVREHALSIRVLPKELLASRQLALQKMQS 687

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 861483604   450 LLGERSHFEEEKQQLASLITNLQSSISNLSQAKEELEQASQAQGAKLNAQvasltaelttlSATLQQQDQELAGLKQQAQ 529
Cdd:TIGR00618  688 EKEQLTYWKEMLAQCQTLLRELETHIEEYDREFNEIENASSSLGSDLAAR-----------EDALNQSLKELMHQARTVL 756

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 861483604   530 KKQAQLAQSLQQQEQASQGLRHQVEQLSGSLKQKEKQLEEAARELDASRRDHAQQLATAAKAQETSLRERDAACQQLEAL 609
Cdd:TIGR00618  757 KARTEAHFNNNEEVTAALQTGAELSHLAAEIQFFNRLREEDTHLLKTLEAEIGQEIPSDEDILNLQCETLVQEEEQFLSR 836

                          410       420       430       440
                   ....*....|....*....|....*....|....*....|....*.
gi 861483604   610 EKEKAAKLEILQQQLQAANEAQDSAQnsvtQAQREKAELSQKVEEL 655
Cdd:TIGR00618  837 LEEKSATLGEITHQLLKYEECSKQLA----QLTQEQAKIIQLSDKL 878
mukB PRK04863
chromosome partition protein MukB;
356-777 5.17e-05

chromosome partition protein MukB;


Pssm-ID: 235316 [Multi-domain]  Cd Length: 1486  Bit Score: 48.80  E-value: 5.17e-05
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 861483604  356 VEKQAHLEKELSTALQDKKCLEEKNEILQGKLSQLEERLAQLPE-----SPRQEKgeVLGDVLQLESLKQEAATLATNNT 430
Cdd:PRK04863  285 LEEALELRRELYTSRRQLAAEQYRLVEMARELAELNEAESDLEQdyqaaSDHLNL--VQTALRQQEKIERYQADLEELEE 362

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 861483604  431 QLQARVEMLENEQGQKEAQllgershfEEEKQQLASLITNLQSSISNLSQAKEELE-------QASQA-QGAKLNAQVAS 502
Cdd:PRK04863  363 RLEEQNEVVEEADEQQEEN--------EARAEAAEEEVDELKSQLADYQQALDVQQtraiqyqQAVQAlERAKQLCGLPD 434

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 861483604  503 LTAE-LTTLSATLQQQDQELAglkqqaqkkqaqlaqslqqqeQASQGLRHQVEQLSGSLKQKEKQLEEAARELDASRRDH 581
Cdd:PRK04863  435 LTADnAEDWLEEFQAKEQEAT---------------------EELLSLEQKLSVAQAAHSQFEQAYQLVRKIAGEVSRSE 493

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 861483604  582 AQQLATAAKAQETSLRERDAACQQLEAlekeKAAKLEILQQQLQAANEAQDSAQNSVTQAQREKAELSQKVEELHALIEA 661
Cdd:PRK04863  494 AWDVARELLRRLREQRHLAEQLQQLRM----RLSELEQRLRQQQRAERLLAEFCKRLGKNLDDEDELEQLQEELEARLES 569

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 861483604  662 AHQEQCEAQTQVAALEARLKAEQQKATEREKVAQEKAQLQEQLWSLEESLkitkGSLEEEKCRAAAALEEHQHHISEMEA 741
Cdd:PRK04863  570 LSESVSEARERRMALRQQLEQLQARIQRLAARAPAWLAAQDALARLREQS----GEEFEDSQDVTEYMQQLLERERELTV 645

                         410       420       430
                  ....*....|....*....|....*....|....*.
gi 861483604  742 ESRSLAEQHKQERKELEEEKAKRRGLGVQLQQLAET 777
Cdd:PRK04863  646 ERDELAARKQALDEEIERLSQPGGSEDPRLNALAER 681
Smc COG1196
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ...
 1524-1699 6.85e-05

Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 440809 [Multi-domain]  Cd Length: 983  Bit Score: 48.01  E-value: 6.85e-05
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 861483604 1524 ERQRFQEER-QKLTAQVEQLEVfqREQTKKVEELSKKLADYDQASKVQQQKLKAFQAQGGESQQEAQRLQTQLNELQVQL 1602
Cdd:COG1196   206 ERQAEKAERyRELKEELKELEA--ELLLLKLRELEAELEELEAELEELEAELEELEAELAELEAELEELRLELEELELEL 283

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 861483604 1603 S---QKEQAAEHYKVQMEKAKTHYDAKKQQNQELqeqlqgLEQLQKENKELRAEAERLGQELQQAGLKTKEAEQTCRHLT 1679
Cdd:COG1196   284 EeaqAEEYELLAELARLEQDIARLEERRRELEER------LEELEEELAELEEELEELEEELEELEEELEEAEEELEEAE 357

                         170       180
                  ....*....|....*....|
gi 861483604 1680 AQVRSLEAQVAHADQQLREL 1699
Cdd:COG1196   358 AELAEAEEALLEAEAELAEA 377
YhaN COG4717
Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown];
215-627 7.93e-05

Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown];


Pssm-ID: 443752 [Multi-domain]  Cd Length: 641  Bit Score: 47.84  E-value: 7.93e-05
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 861483604  215 QMRRLKKQLADERNNRDELELELAEHRKLLTEKDAQISMMQQRIDRLALLNEKQAASPL---EPRELEELRGKNESLTFR 291
Cdd:COG4717    82 EAEEKEEEYAELQEELEELEEELEELEAELEELREELEKLEKLLQLLPLYQELEALEAElaeLPERLEELEERLEELREL 161

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 861483604  292 LHETLKQCQDLKTEKGQMDRKINQLSEENGDlsfKLREFASNLQQLQGALNELTEEhskaTQQWVEKQAHLEKELSTALQ 371
Cdd:COG4717   162 EEELEELEAELAELQEELEELLEQLSLATEE---ELQDLAEELEELQQRLAELEEE----LEEAQEELEELEEELEQLEN 234

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 861483604  372 DKKCLEEKNEILQGKLSQ--------LEERLAQLPESPRQEKG------EVLGDVLQLESLKQEAATLATNNTQLQARVE 437
Cdd:COG4717   235 ELEAAALEERLKEARLLLliaaallaLLGLGGSLLSLILTIAGvlflvlGLLALLFLLLAREKASLGKEAEELQALPALE 314

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 861483604  438 MLENEQGQKEAQLLGERSHFE-EEKQQLASLITNLQSSISNLSQAKEELEQASQAQGAKLNAQVASLTAElTTLSATLQQ 516
Cdd:COG4717   315 ELEEEELEELLAALGLPPDLSpEELLELLDRIEELQELLREAEELEEELQLEELEQEIAALLAEAGVEDE-EELRAALEQ 393

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 861483604  517 QDQELAGLKQQAQKKQAQLAQSLQQQEQASQGLRHQVEQLSGSLKQKEKQLEEAARELDASRRDHAQQLATAAKAQETS- 595
Cdd:COG4717   394 AEEYQELKEELEELEEQLEELLGELEELLEALDEEELEEELEELEEELEELEEELEELREELAELEAELEQLEEDGELAe 473

                         410       420       430
                  ....*....|....*....|....*....|...
gi 861483604  596 -LRERDAACQQLEALEKEkAAKLEILQQQLQAA 627
Cdd:COG4717   474 lLQELEELKAELRELAEE-WAALKLALELLEEA 505
YhaN COG4717
Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown];
550-938 7.93e-05

Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown];


Pssm-ID: 443752 [Multi-domain]  Cd Length: 641  Bit Score: 47.84  E-value: 7.93e-05
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 861483604  550 RHQVEQLSGSLKQKEKQLEEAARELDASRRDHAQ-QLATAAKAQETSLRERDAACQQLEALEKEKAAKLEILQQQLQAAN 628
Cdd:COG4717    80 LKEAEEKEEEYAELQEELEELEEELEELEAELEElREELEKLEKLLQLLPLYQELEALEAELAELPERLEELEERLEELR 159

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 861483604  629 EAQDSAQNSVTQAQREKAELSQKVEELHALIEAAHQEQCEAQTQVAALEARLKAEQQKATER-EKVAQEKAQLQEQLWSL 707
Cdd:COG4717   160 ELEEELEELEAELAELQEELEELLEQLSLATEEELQDLAEELEELQQRLAELEEELEEAQEElEELEEELEQLENELEAA 239

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 861483604  708 EESLKITKGS----LEEEKCRAAAALEEHQHHISEMEAESRSLAEQHKQERKELEEEKAKRRGLGVQLQQLAETHQAETK 783
Cdd:COG4717   240 ALEERLKEARllllIAAALLALLGLGGSLLSLILTIAGVLFLVLGLLALLFLLLAREKASLGKEAEELQALPALEELEEE 319

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 861483604  784 ALRQELAKARTSNNMAEREVELLVKEVKTWRKRYEDSQQGETQYGLQEQLTTLKEEYEKSCQELRETKEKMAgiEAHSEL 863
Cdd:COG4717   320 ELEELLAALGLPPDLSPEELLELLDRIEELQELLREAEELEEELQLEELEQEIAALLAEAGVEDEEELRAAL--EQAEEY 397

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 861483604  864 QigQHQSELAQLHANLARALQQVQEK---------ENRAQKLADDLSTLQEKMAATSKEVARLEALVRKAGEQQETASLE 934
Cdd:COG4717   398 Q--ELKEELEELEEQLEELLGELEELlealdeeelEEELEELEEELEELEEELEELREELAELEAELEQLEEDGELAELL 475


                  ....
gi 861483604  935 LLKE 938
Cdd:COG4717   476 QELE 479
SMC_prok_A TIGR02169
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of ...
 1301-1701 8.50e-05

chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. It is found in a single copy and is homodimeric in prokaryotes, but six paralogs (excluded from this family) are found in eukarotes, where SMC proteins are heterodimeric. This family represents the SMC protein of archaea and a few bacteria (Aquifex, Synechocystis, etc); the SMC of other bacteria is described by TIGR02168. The N- and C-terminal domains of this protein are well conserved, but the central hinge region is skewed in composition and highly divergent. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274009 [Multi-domain]  Cd Length: 1164  Bit Score: 47.76  E-value: 8.50e-05
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 861483604  1301 EEVEKQRAASENLRQELASQAERAEELGQELKAWQEKFFQKE--QALSAlQLEHTSTQALVSELLPAKHLCQQLQAEQVA 1378
Cdd:TIGR02169  170 RKKEKALEELEEVEENIERLDLIIDEKRQQLERLRREREKAEryQALLK-EKREYEGYELLKEKEALERQKEAIERQLAS 248

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 861483604  1379 AEkrhrEELEQSKQAAGGLRTELMRAQRELGELVPLRQKVAEQERAaqQLRAEKASYAEQLSMLKKAHGLLAEENRGLGE 1458
Cdd:TIGR02169  249 LE----EELEKLTEEISELEKRLEEIEQLLEELNKKIKDLGEEEQL--RVKEKIGELEAEIASLERSIAEKERELEDAEE 322

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 861483604  1459 RanlgRQFLEVELDQAREKyIQELAAVRGDAETRLAEMRQEVQSTTHELEVMTAKYEGAKVKVLEERQRFQEERQKLTAQ 1538
Cdd:TIGR02169  323 R----LAKLEAEIDKLLAE-IEELEREIEEERKRRDKLTEEYAELKEELEDLRAELEEVDKEFAETRDELKDYREKLEKL 397

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 861483604  1539 VEQLEVFQREQTKKVEE---LSKKLADYDQASKVQQQKLKAfqaqggesqqeaqrLQTQLNELQVQLSQKEQAAEHYKVQ 1615
Cdd:TIGR02169  398 KREINELKRELDRLQEElqrLSEELADLNAAIAGIEAKINE--------------LEEEKEDKALEIKKQEWKLEQLAAD 463

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 861483604  1616 MEKAKTHYDAKKQQnqelqeqlqgLEQLQKENKELRaeaerlgQELQQAGLKTKEAEQTCRHLTAQVRSLEAQVAHADQQ 1695
Cdd:TIGR02169  464 LSKYEQELYDLKEE----------YDRVEKELSKLQ-------RELAEAEAQARASEERVRGGRAVEEVLKASIQGVHGT 526


                   ....*.
gi 861483604  1696 LRELGK 1701
Cdd:TIGR02169  527 VAQLGS 532
CCDC158 pfam15921
Coiled-coil domain-containing protein 158; CCDC158 is a family of proteins found in eukaryotes. ...
 454-1224 8.65e-05

Coiled-coil domain-containing protein 158; CCDC158 is a family of proteins found in eukaryotes. The function is not known.


Pssm-ID: 464943 [Multi-domain]  Cd Length: 1112  Bit Score: 47.81  E-value: 8.65e-05
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 861483604   454 RSHFEEEKQQLASLITNLQSSISNLSQAKEELEQASQAQGAKLNAQVASLTAELTTLSATLQQQDQELAGLKQQAQKKQA 533
Cdd:pfam15921   73 KEHIERVLEEYSHQVKDLQRRLNESNELHEKQKFYLRQSVIDLQTKLQEMQMERDAMADIRRRESQSQEDLRNQLQNTVH 152

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 861483604   534 QLAQSLQQQEQASQGLRHQVEQLSGSLKQKEKQLEE--------------AARELDASRRDHAQQLATAAKAQetsLRER 599
Cdd:pfam15921  153 ELEAAKCLKEDMLEDSNTQIEQLRKMMLSHEGVLQEirsilvdfeeasgkKIYEHDSMSTMHFRSLGSAISKI---LREL 229

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 861483604   600 DAACQ-----------QLEALEKEKAAKLEILQQQlqaaneAQDSAQNSVTQAQREKAELSQKVEELHALIEAAHQE--- 665
Cdd:pfam15921  230 DTEISylkgrifpvedQLEALKSESQNKIELLLQQ------HQDRIEQLISEHEVEITGLTEKASSARSQANSIQSQlei 303

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 861483604   666 -QCEAQTQVAALEARLKAEQQKATE-REKVAQEKAQLQEQLWSLEESLKITKGSLEEEKCRAAAALEEHQHHISEMEaes 743
Cdd:pfam15921  304 iQEQARNQNSMYMRQLSDLESTVSQlRSELREAKRMYEDKIEELEKQLVLANSELTEARTERDQFSQESGNLDDQLQ--- 380

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 861483604   744 RSLAEQHKQERK-ELEEEKAKRrglgvqLQQLAETHQAETKALRQELakarTSNNMAEREVELLVKEVKTWRKRYEDSQQ 822
Cdd:pfam15921  381 KLLADLHKREKElSLEKEQNKR------LWDRDTGNSITIDHLRREL----DDRNMEVQRLEALLKAMKSECQGQMERQM 450

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 861483604   823 GETQYGLQ--EQLTTLKEEYEKSCQELRETKEKMAGieahSELQIGQHQSELAQLHANLaralqqvQEKENRAQKLADDL 900
Cdd:pfam15921  451 AAIQGKNEslEKVSSLTAQLESTKEMLRKVVEELTA----KKMTLESSERTVSDLTASL-------QEKERAIEATNAEI 519

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 861483604   901 STLQEKMAATSKEVARLealvRKAGE--QQETASLELLKEPPKTRDRESEWVEEQ---QGQQLCSTQAALRAMEREAEQM 975
Cdd:pfam15921  520 TKLRSRVDLKLQELQHL----KNEGDhlRNVQTECEALKLQMAEKDKVIEILRQQienMTQLVGQHGRTAGAMQVEKAQL 595

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 861483604   976 GTELEKLRAALMESQGQQQEERGQQEREVARLTqergqaeaDLALEKaakaeleMRLQNALNEQQAEFANLQEALSRALS 1055
Cdd:pfam15921  596 EKEINDRRLELQEFKILKDKKDAKIRELEARVS--------DLELEK-------VKLVNAGSERLRAVKDIKQERDQLLN 660

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 861483604  1056 EKEGKDQELSKLCEQEAVQRMELK----ELLQTVEQLKAQLAKKEKEQQQSARGASGENASGMGTQSEAVGKMEALRAKV 1131
Cdd:pfam15921  661 EVKTSRNELNSLSEDYEVLKRNFRnkseEMETTTNKLKMQLKSAQSELEQTRNTLKSMEGSDGHAMKVAMGMQKQITAKR 740

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 861483604  1132 SKLEQQCQQQQEEADSLARSLESERAFHVERDRALETLQGQLEEKARELGYSQAASASAQR---ELATLRAKAQDHSKAE 1208
Cdd:pfam15921  741 GQIDALQSKIQFLEEAMTNANKEKHFLKEEKNKLSQELSTVATEKNKMAGELEVLRSQERRlkeKVANMEVALDKASLQF 820

                          810
                   ....*....|....*.
gi 861483604  1209 EEWKAQVARGQQEAVR 1224
Cdd:pfam15921  821 AECQDIIQRQEQESVR 836
PRK09039 PRK09039
peptidoglycan -binding protein;
556-692 8.96e-05

peptidoglycan -binding protein;


Pssm-ID: 181619 [Multi-domain]  Cd Length: 343  Bit Score: 46.88  E-value: 8.96e-05
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 861483604  556 LSGSLKQKEKQLEEAARELD------ASRRDHAQQLATAAKAQETSLRERDAACQQLEALEKEKAAKLEILQQQLQAANE 629
Cdd:PRK09039   44 LSREISGKDSALDRLNSQIAeladllSLERQGNQDLQDSVANLRASLSAAEAERSRLQALLAELAGAGAAAEGRAGELAQ 123

                          90       100       110       120       130       140       150
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 861483604  630 AQDSAQNSVTQAQREKAELSQKVEEL-------HALIEAAHQEQCEAQTQVAALEARLK-AEQQKATEREK 692
Cdd:PRK09039  124 ELDSEKQVSARALAQVELLNQQIAALrrqlaalEAALDASEKRDRESQAKIADLGRRLNvALAQRVQELNR 194
DUF5401 pfam17380
Family of unknown function (DUF5401); This is a family of unknown function found in ...
 617-923 9.10e-05

Family of unknown function (DUF5401); This is a family of unknown function found in Chromadorea.


Pssm-ID: 375164 [Multi-domain]  Cd Length: 722  Bit Score: 47.81  E-value: 9.10e-05
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 861483604   617 LEILQQQlQAANEAQDSAQNSVTQAQR---EKAELSQKVEELHALIEA--AHQEQCEAQTQVAALEARLKAEQQKATERE 691
Cdd:pfam17380  275 LHIVQHQ-KAVSERQQQEKFEKMEQERlrqEKEEKAREVERRRKLEEAekARQAEMDRQAAIYAEQERMAMERERELERI 353

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 861483604   692 KVAQEKAQLqeqlwsleESLKITKGSLEEEKCRAAAALE-EHQHHISEMEAESRSLAEQHKQERKELEEEKAKRRGLGVQ 770
Cdd:pfam17380  354 RQEERKREL--------ERIRQEEIAMEISRMRELERLQmERQQKNERVRQELEAARKVKILEEERQRKIQQQKVEMEQI 425

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 861483604   771 LQQLAETHQAETKALRQELAKARTSNNMAEREVEllvKEVKTWRKRYEDSQQGETQYGLQEQLTTLKEEYEKSC--QELR 848
Cdd:pfam17380  426 RAEQEEARQREVRRLEEERAREMERVRLEEQERQ---QQVERLRQQEEERKRKKLELEKEKRDRKRAEEQRRKIleKELE 502

                          250       260       270       280       290       300       310
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 861483604   849 ETKEKMagIEAHSELQIGQHQSELAQlHANLARALQQVQEKENRAQKLADDLSTLQEKMAATSKEVARLEALVRK 923
Cdd:pfam17380  503 ERKQAM--IEEERKRKLLEKEMEERQ-KAIYEEERRREAEEERRKQQEMEERRRIQEQMRKATEERSRLEAMERE 574
PRK03918 PRK03918
DNA double-strand break repair ATPase Rad50;
689-1349 9.15e-05

DNA double-strand break repair ATPase Rad50;


Pssm-ID: 235175 [Multi-domain]  Cd Length: 880  Bit Score: 47.75  E-value: 9.15e-05
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 861483604  689 EREKVAQEKAQLqEQLWSLEESLKITKGSLEEEKCRAA---AALEEHQHHISEMEAESRSLAEQHKQERKELEEEKAKRR 765
Cdd:PRK03918  146 SREKVVRQILGL-DDYENAYKNLGEVIKEIKRRIERLEkfiKRTENIEELIKEKEKELEEVLREINEISSELPELREELE 224

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 861483604  766 GLGVQLQQLaethqaetKALRQELAKARTSNNMAEREVELLVKEVKTWRKRYEDSQQG----ETQYGLQEQLTTLKEEYE 841
Cdd:PRK03918  225 KLEKEVKEL--------EELKEEIEELEKELESLEGSKRKLEEKIRELEERIEELKKEieelEEKVKELKELKEKAEEYI 296

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 861483604  842 KSCQELRETKEKMAGIEahselqigQHQSELAQLHANLARALQQVQEKENRAQKLADDLSTLQEKMAATSKEVARLEALV 921
Cdd:PRK03918  297 KLSEFYEEYLDELREIE--------KRLSRLEEEINGIEERIKELEEKEERLEELKKKLKELEKRLEELEERHELYEEAK 368

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 861483604  922 RKAGEqqetasLELLKEppKTRDRESEWVEEQqgqqlcstqaaLRAMEREAEQMGTELEKLRAalmesqgqqqeergqqe 1001
Cdd:PRK03918  369 AKKEE------LERLKK--RLTGLTPEKLEKE-----------LEELEKAKEEIEEEISKITA----------------- 412

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 861483604 1002 rEVARLTQERGQAEADLALEKAAKAEL--------EMRLQNALNEQQAEFANLQEALSRALSEKEGKDQELSKLcEQEAV 1073
Cdd:PRK03918  413 -RIGELKKEIKELKKAIEELKKAKGKCpvcgreltEEHRKELLEEYTAELKRIEKELKEIEEKERKLRKELREL-EKVLK 490

                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 861483604 1074 QRMELKELLQTVEQLKAQLAKKEKEQQQSARGASGEnasgmgtqseavgkMEALRAKVSKLEQQCQQQQEEADSLArSLE 1153
Cdd:PRK03918  491 KESELIKLKELAEQLKELEEKLKKYNLEELEKKAEE--------------YEKLKEKLIKLKGEIKSLKKELEKLE-ELK 555

                         490       500       510       520       530       540       550       560
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 861483604 1154 SERAFHVERDRALETLQGQLEEKARELGYSqaasasaqrELATLRAKAQDHSKAEEEWkaqvargqQEAVRKGSLISSLE 1233
Cdd:PRK03918  556 KKLAELEKKLDELEEELAELLKELEELGFE---------SVEELEERLKELEPFYNEY--------LELKDAEKELEREE 618

                         570       580       590       600       610       620       630       640
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 861483604 1234 EEVSILNRQVLEKEgesKELKRLVIAESEKSQKLEERLRLLQMETasnSARAAERSSALREEVQSLREEVEkqraASENL 1313
Cdd:PRK03918  619 KELKKLEEELDKAF---EELAETEKRLEELRKELEELEKKYSEEE---YEELREEYLELSRELAGLRAELE----ELEKR 688

                         650       660       670
                  ....*....|....*....|....*....|....*.
gi 861483604 1314 RQELASQAERAEELGQELKAWQEKFFQKEQALSALQ 1349
Cdd:PRK03918  689 REEIKKTLEKLKEELEEREKAKKELEKLEKALERVE 724
PRK02224 PRK02224
DNA double-strand break repair Rad50 ATPase;
1458-1702 9.22e-05

DNA double-strand break repair Rad50 ATPase;


Pssm-ID: 179385 [Multi-domain]  Cd Length: 880  Bit Score: 47.73  E-value: 9.22e-05
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 861483604 1458 ERANLGRQFLEVELDQAREKYIQELAAVRGDAET----RLAEMRQEVQSTTHELEVMTAKYEGAK------VKVLEERQR 1527
Cdd:PRK02224  169 ERASDARLGVERVLSDQRGSLDQLKAQIEEKEEKdlheRLNGLESELAELDEEIERYEEQREQARetrdeaDEVLEEHEE 248

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 861483604 1528 FQEERQKLTAQVEQLEVFQREQTKKVEELSKKLADYDQASKVQQQKLKAFQAQGGESQQEAQRLQTQLNELQVQLSQKEQ 1607
Cdd:PRK02224  249 RREELETLEAEIEDLRETIAETEREREELAEEVRDLRERLEELEEERDDLLAEAGLDDADAEAVEARREELEDRDEELRD 328

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 861483604 1608 AAEHYKVQMEKAKTHYDAKKQQNqelqeqlqglEQLQKENKELRAEAERLGQELQQAGLKTKEAEQTCRHLTAQVRSLEA 1687
Cdd:PRK02224  329 RLEECRVAAQAHNEEAESLREDA----------DDLEERAEELREEAAELESELEEAREAVEDRREEIEELEEEIEELRE 398

                         250
                  ....*....|....*
gi 861483604 1688 QVAHADQQLRELGKF 1702
Cdd:PRK02224  399 RFGDAPVDLGNAEDF 413
mukB PRK04863
chromosome partition protein MukB;
829-1609 1.09e-04

chromosome partition protein MukB;


Pssm-ID: 235316 [Multi-domain]  Cd Length: 1486  Bit Score: 47.64  E-value: 1.09e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 861483604  829 LQEQLTTLKEEYEKSCQELRETKEKMAGIEahSELQIGQHQSELAQLHANLARALQQVQEKENRAQklaDDLSTLQEKMA 908
Cdd:PRK04863  291 LRRELYTSRRQLAAEQYRLVEMARELAELN--EAESDLEQDYQAASDHLNLVQTALRQQEKIERYQ---ADLEELEERLE 365

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 861483604  909 ATSkevarleALVRKAGEQQETaslellkeppktRDRESEWVEEQQGQ---QLCSTQAALRAMEREAEQMGTELEKLRAA 985
Cdd:PRK04863  366 EQN-------EVVEEADEQQEE------------NEARAEAAEEEVDElksQLADYQQALDVQQTRAIQYQQAVQALERA 426

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 861483604  986 lmesqgQQQEERGQQEREVARLTQERGQAEADLALEKAAKAELEMRLQNALNEQQAEFANLQEALSRALSEKEGKDQELS 1065
Cdd:PRK04863  427 ------KQLCGLPDLTADNAEDWLEEFQAKEQEATEELLSLEQKLSVAQAAHSQFEQAYQLVRKIAGEVSRSEAWDVARE 500

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 861483604 1066 KLCEQEavqrmELKELLQTVEQLKAQLA--KKEKEQQQSARGASGENASGMGTQSEAVGKMEALRAkvskleqqcqqqqe 1143
Cdd:PRK04863  501 LLRRLR-----EQRHLAEQLQQLRMRLSelEQRLRQQQRAERLLAEFCKRLGKNLDDEDELEQLQE-------------- 561

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 861483604 1144 EADSLARSLESERAFHVERDRALETLQGQLEEKARELGYSQAASASAQRELATLRAK---AQDHSKAEEEWKAQVARGQQ 1220
Cdd:PRK04863  562 ELEARLESLSESVSEARERRMALRQQLEQLQARIQRLAARAPAWLAAQDALARLREQsgeEFEDSQDVTEYMQQLLERER 641

                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 861483604 1221 EAVRKGSLISSLEEEVSILNRQVLEKEG-ESKELKRL-------VIAE-------------------------------- 1260
Cdd:PRK04863  642 ELTVERDELAARKQALDEEIERLSQPGGsEDPRLNALaerfggvLLSEiyddvsledapyfsalygparhaivvpdlsda 721

                         490       500       510       520       530       540       550       560
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 861483604 1261 SEKSQKLEERLRLLQMETASNSARAAERSSALREEVQSLREEVEKQ-------------RAASENLRQELASQAERAEEL 1327
Cdd:PRK04863  722 AEQLAGLEDCPEDLYLIEGDPDSFDDSVFSVEELEKAVVVKIADRQwrysrfpevplfgRAAREKRIEQLRAEREELAER 801

                         570       580       590       600       610       620       630       640
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 861483604 1328 GQELKAWQEKFFQKEQALSALQLEHTSTQALVSELLPAKHLCQQLQ------AEQVAAEKRHREELEQSKQAAGGLRTEL 1401
Cdd:PRK04863  802 YATLSFDVQKLQRLHQAFSRFIGSHLAVAFEADPEAELRQLNRRRVeleralADHESQEQQQRSQLEQAKEGLSALNRLL 881

                         650       660       670       680       690       700       710       720
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 861483604 1402 MRAQRELGELVPLR-QKVAEQERAAQQLRAEKASYAEQLSMLKKAHGLLAEEnrglgeranlgrqflEVELDQAREKYIQ 1480
Cdd:PRK04863  882 PRLNLLADETLADRvEEIREQLDEAEEAKRFVQQHGNALAQLEPIVSVLQSD---------------PEQFEQLKQDYQQ 946

                         730       740       750       760       770       780       790       800
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 861483604 1481 elaavrgdAETRLAEMRQEVQSTTHELEVMTA-KYEGAkVKVLEERQRFQEerqKLTAQVEQLEVFQREQTkkvEELSKK 1559
Cdd:PRK04863  947 --------AQQTQRDAKQQAFALTEVVQRRAHfSYEDA-AEMLAKNSDLNE---KLRQRLEQAEQERTRAR---EQLRQA 1011

                         810       820       830       840       850
                  ....*....|....*....|....*....|....*....|....*....|
gi 861483604 1560 LADYDQASKVQQQKLKAFQAQggesQQEAQRLQTQLNELQVQLSQKEQAA 1609
Cdd:PRK04863 1012 QAQLAQYNQVLASLKSSYDAK----RQMLQELKQELQDLGVPADSGAEER 1057
CCDC158 pfam15921
Coiled-coil domain-containing protein 158; CCDC158 is a family of proteins found in eukaryotes. ...
 1148-1711 1.20e-04

Coiled-coil domain-containing protein 158; CCDC158 is a family of proteins found in eukaryotes. The function is not known.


Pssm-ID: 464943 [Multi-domain]  Cd Length: 1112  Bit Score: 47.42  E-value: 1.20e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 861483604  1148 LARSLESERAFHVERDRALETLQGQLEEKARELGYSQAASASAQRElatlrakaqdHSKAEEEWKAQVARG--QQEAVR- 1224
Cdd:pfam15921   90 LQRRLNESNELHEKQKFYLRQSVIDLQTKLQEMQMERDAMADIRRR----------ESQSQEDLRNQLQNTvhELEAAKc 159

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 861483604  1225 -KGSLISSLEEEVSILNRQVLEKEGESKELKRLVIAESEKS-QKLEERLRLLQMETASNSARAAERSSALREEVQSLREE 1302
Cdd:pfam15921  160 lKEDMLEDSNTQIEQLRKMMLSHEGVLQEIRSILVDFEEASgKKIYEHDSMSTMHFRSLGSAISKILRELDTEISYLKGR 239

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 861483604  1303 VEKQRAASENLRQElaSQAERAEELGQELKAWQEKFFQKEQALSALQLEHTSTQALVSELLPAKHLCQQLQAEQVAAEKR 1382
Cdd:pfam15921  240 IFPVEDQLEALKSE--SQNKIELLLQQHQDRIEQLISEHEVEITGLTEKASSARSQANSIQSQLEIIQEQARNQNSMYMR 317

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 861483604  1383 HREELEQSkqaAGGLRTELMRAQR-------EL-GELVPLRQKVAEQERAAQQLRAEKASYAEQLSML-------KKAHG 1447
Cdd:pfam15921  318 QLSDLEST---VSQLRSELREAKRmyedkieELeKQLVLANSELTEARTERDQFSQESGNLDDQLQKLladlhkrEKELS 394

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 861483604  1448 LLAEENRGLGERaNLGRQfleVELDQAREKyiqelaavrgdaetrLAEMRQEVQSTTHELEVMTAKYEGAKVKVLEERQR 1527
Cdd:pfam15921  395 LEKEQNKRLWDR-DTGNS---ITIDHLRRE---------------LDDRNMEVQRLEALLKAMKSECQGQMERQMAAIQG 455

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 861483604  1528 FQEERQKLTAQVEQLEVFQREQTKKVEELSKKLADYDQASKV-------QQQKLKAFQAQGGESQQEAQRLQTQLNELQv 1600
Cdd:pfam15921  456 KNESLEKVSSLTAQLESTKEMLRKVVEELTAKKMTLESSERTvsdltasLQEKERAIEATNAEITKLRSRVDLKLQELQ- 534

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 861483604  1601 QLSQKEQAAEHYKVQMEKAKTHYDAKKQQNQELQEQLQGLEQLQKENKE----LRAEAERLGQELQQAGLKTKEAEQTCR 1676
Cdd:pfam15921  535 HLKNEGDHLRNVQTECEALKLQMAEKDKVIEILRQQIENMTQLVGQHGRtagaMQVEKAQLEKEINDRRLELQEFKILKD 614

                          570       580       590
                   ....*....|....*....|....*....|....*
gi 861483604  1677 HLTAQVRSLEAQVahADQQLRELGKFQVASDALKS 1711
Cdd:pfam15921  615 KKDAKIRELEARV--SDLELEKVKLVNAGSERLRA 647
YhaN COG4717
Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown];
738-1180 1.33e-04

Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown];


Pssm-ID: 443752 [Multi-domain]  Cd Length: 641  Bit Score: 47.07  E-value: 1.33e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 861483604  738 EMEAESRSLAEQHKQERKELEEEKAKRRGLGVQLQQLAEThQAETKALRQELAKARTSNNMAEREVELLVKEVKTWRKRY 817
Cdd:COG4717    54 EADELFKPQGRKPELNLKELKELEEELKEAEEKEEEYAEL-QEELEELEEELEELEAELEELREELEKLEKLLQLLPLYQ 132

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 861483604  818 EDSQqgetqygLQEQLTTLKEEYEKSCQELRETKEKMAGIEAHSElqigqhqsELAQLHANLARALQQV-QEKENRAQKL 896
Cdd:COG4717   133 ELEA-------LEAELAELPERLEELEERLEELRELEEELEELEA--------ELAELQEELEELLEQLsLATEEELQDL 197

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 861483604  897 ADDLSTLQEKMAATSKEVARLEALVRKAGEQQETASLELLKEPPKTRDRESEWVeeqqgQQLCSTQAALRAMEREAEQMG 976
Cdd:COG4717   198 AEELEELQQRLAELEEELEEAQEELEELEEELEQLENELEAAALEERLKEARLL-----LLIAAALLALLGLGGSLLSLI 272

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 861483604  977 TELEKLRAALMESQGQQQEERGQQEREVARLTQERGQAEADLALEKAAKAELEMRLQNALNEQQAEFANL---QEALSRA 1053
Cdd:COG4717   273 LTIAGVLFLVLGLLALLFLLLAREKASLGKEAEELQALPALEELEEEELEELLAALGLPPDLSPEELLELldrIEELQEL 352

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 861483604 1054 LSEKEGKDQELSKLCEQEAVQRMELKELLQTVEQLKAQLAKKEKEQQQSARGASGE----NASGMGTQSEAVGKMEALRA 1129
Cdd:COG4717   353 LREAEELEEELQLEELEQEIAALLAEAGVEDEEELRAALEQAEEYQELKEELEELEeqleELLGELEELLEALDEEELEE 432

                         410       420       430       440       450
                  ....*....|....*....|....*....|....*....|....*....|...
gi 861483604 1130 KVSKLEQQCQQQQEEADSLARSLESERA--FHVERDRALETLQGQLEEKAREL 1180
Cdd:COG4717   433 ELEELEEELEELEEELEELREELAELEAelEQLEEDGELAELLQELEELKAEL 485
EmrA COG1566
Multidrug resistance efflux pump EmrA [Defense mechanisms];
577-710 1.55e-04

Multidrug resistance efflux pump EmrA [Defense mechanisms];


Pssm-ID: 441174 [Multi-domain]  Cd Length: 331  Bit Score: 46.19  E-value: 1.55e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 861483604  577 SRRDHAQQLATAAKAQETSLRERDAACQQLEALEKEKA---AKLEILQQQLQAANEAQdsAQNSVTQAQREKAElsqkve 653
Cdd:COG1566    83 AALAQAEAQLAAAEAQLARLEAELGAEAEIAAAEAQLAaaqAQLDLAQRELERYQALY--KKGAVSQQELDEAR------ 154

                          90       100       110       120       130
                  ....*....|....*....|....*....|....*....|....*....|....*..
gi 861483604  654 elhALIEAAHQEQCEAQTQVAALEARLKAEQQKATEREKVAQEKAQLQEQLWSLEES 710
Cdd:COG1566   155 ---AALDAAQAQLEAAQAQLAQAQAGLREEEELAAAQAQVAQAEAALAQAELNLART 208
YqiK COG2268
Uncharacterized membrane protein YqiK, contains Band7/PHB/SPFH domain [Function unknown];
561-687 1.92e-04

Uncharacterized membrane protein YqiK, contains Band7/PHB/SPFH domain [Function unknown];


Pssm-ID: 441869 [Multi-domain]  Cd Length: 439  Bit Score: 46.40  E-value: 1.92e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 861483604  561 KQKEKQLEEAARELDASRRDHAQQLATAAKAQETSLRERDAAcqqleALEKEKAAKLEILQQQLQAANEAQDSAQNSVTQ 640
Cdd:COG2268   219 ANREAEEAELEQEREIETARIAEAEAELAKKKAEERREAETA-----RAEAEAAYEIAEANAEREVQRQLEIAEREREIE 293

                          90       100       110       120
                  ....*....|....*....|....*....|....*....|....*..
gi 861483604  641 AQREKAELSQKVEElhalieAAHQEQCEAQTQVAALEARLKAEQQKA 687
Cdd:COG2268   294 LQEKEAEREEAELE------ADVRKPAEAEKQAAEAEAEAEAEAIRA 334
DUF1633 pfam07794
Protein of unknown function (DUF1633); This family contains sequences derived from a group of ...
 554-748 2.01e-04

Protein of unknown function (DUF1633); This family contains sequences derived from a group of hypothetical proteins expressed by Arabidopsis thaliana. These sequences are highly similar and the region concerned is about 100 residues long.


Pssm-ID: 116408 [Multi-domain]  Cd Length: 698  Bit Score: 46.42  E-value: 2.01e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 861483604   554 EQLSGSLKQKEKQLEE---AARELDAS-RRDHAQQLATAAKAQETSLRERDAACQQLEALEKEKAAKLEILQQQLQAANE 629
Cdd:pfam07794  440 KQVGCSLRASAKEGEEgerAIREEDPHlGADQDREVRFGAEGIVPGIERLKIELSTSKDLEKGYAEKIGFMEMEFGGLEA 519

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 861483604   630 AQDSAQNSVTQAQREKAELSQKVEELHALIEAAHQEQCEAQTQVAALEARLKAeqqKATEREKVAQEKAQLQEQLWSLEE 709
Cdd:pfam07794  520 DKQMARNQIHRLEEKKDELSKKVLDLTSIAQGAKKAVHDAKVELAAAYLKLLA---GIKDKWVAKKEFTVLEGQAAEVES 596

                          170       180       190       200
                   ....*....|....*....|....*....|....*....|....*
gi 861483604   710 SL----KITKGS--LEEEKCRAAAALEEHQHHISEMEAESRSLAE 748
Cdd:pfam07794  597 NLalidQITKAAidLTLEKPRFQAEIDDLEARCKLKEVSDFTLSK 641
PHA03307 PHA03307
transcriptional regulator ICP4; Provisional
 1748-2003 2.23e-04

transcriptional regulator ICP4; Provisional


Pssm-ID: 223039 [Multi-domain]  Cd Length: 1352  Bit Score: 46.70  E-value: 2.23e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 861483604 1748 PDGTSVPGEPASPISQRlPPKVESLESLYFTPIPARGPA--PLESSLDSLGEPFLDSGRKTRSA-------------RRR 1812
Cdd:PHA03307  192 EPPPSTPPAAASPRPPR-RSSPISASASSPAPAPGRSAAddAGASSSDSSSSESSGCGWGPENEcplprpapitlptRIW 270

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 861483604 1813 TTQIINITMTKKLDVEEPDSANSSfYSTRSAPASQAGLRATSSTQSLARLGSPDDGNSAllslpgyrpTTRSSTRRSQAG 1892
Cdd:PHA03307  271 EASGWNGPSSRPGPASSSSSPRER-SPSPSPSSPGSGPAPSSPRASSSSSSSRESSSSS---------TSSSSESSRGAA 340

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 861483604 1893 VSSGAPPGRNsfymGTCQDEPeqldDWNRIAELQQRnrvCPPHLKTCYPLESRPSlglatitdeemktgdpqETLRRASM 1972
Cdd:PHA03307  341 VSPGPSPSRS----PSPSRPP----PPADPSSPRKR---PRPSRAPSSPAASAGR-----------------PTRRRARA 392

                         250       260       270
                  ....*....|....*....|....*....|....
gi 861483604 1973 Q---PGQIAEGAGITTRQQRKRVSSETHQGPGTP 2003
Cdd:PHA03307  393 AvagRARRRDATGRFPAGRPRPSPLDAGAASGAF 426
SCP-1 pfam05483
Synaptonemal complex protein 1 (SCP-1); Synaptonemal complex protein 1 (SCP-1) is the major ...
 650-1390 2.71e-04

Synaptonemal complex protein 1 (SCP-1); Synaptonemal complex protein 1 (SCP-1) is the major component of the transverse filaments of the synaptonemal complex. Synaptonemal complexes are structures that are formed between homologous chromosomes during meiotic prophase.


Pssm-ID: 114219 [Multi-domain]  Cd Length: 787  Bit Score: 46.25  E-value: 2.71e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 861483604   650 QKVEELHALIEAAHQEQCEAQTQVAalEARLKAEQQKATEREKVAQEKAQLQEQLWSLEESLKITKGSLEEEKcraaAAL 729
Cdd:pfam05483   42 QKLNFLPMLEQVANSGDCHYQEGLK--DSDFENSEGLSRLYSKLYKEAEKIKKWKVSIEAELKQKENKLQENR----KII 115

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 861483604   730 EEHQHHISEMEAESRSLA---EQHKQERKELEEEKAKRRGLGVQLQQLAETHQAETKALRQELAKARTSNNMAEREVELL 806
Cdd:pfam05483  116 EAQRKAIQELQFENEKVSlklEEEIQENKDLIKENNATRHLCNLLKETCARSAEKTKKYEYEREETRQVYMDLNNNIEKM 195

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 861483604   807 VKEVKTWRKRYEDSQQgetqyglqEQLTTLKEEYEKSCQELRETKEKMAGIEAHSEL---QIGQHQSELAQLHANLARAL 883
Cdd:pfam05483  196 ILAFEELRVQAENARL--------EMHFKLKEDHEKIQHLEEEYKKEINDKEKQVSLlliQITEKENKMKDLTFLLEESR 267

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 861483604   884 QQVQEKENRAQKLADDLSTLQEKMAATSKEVARLEALVRKAGEQQETASlELLKEPPKTRDRESEwVEEQQGQQLCSTQA 963
Cdd:pfam05483  268 DKANQLEEKTKLQDENLKELIEKKDHLTKELEDIKMSLQRSMSTQKALE-EDLQIATKTICQLTE-EKEAQMEELNKAKA 345

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 861483604   964 ALRAMEREAEQMGTELEKLraaLMESQGQQQEERGQQEREVARLTQERGQAEADLALEKAAKAELEmRLQNALNEQQaEF 1043
Cdd:pfam05483  346 AHSFVVTEFEATTCSLEEL---LRTEQQRLEKNEDQLKIITMELQKKSSELEEMTKFKNNKEVELE-ELKKILAEDE-KL 420

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 861483604  1044 ANLQEALSRALSEKEGKDQELSKLCEQEAVQRMELKELLQTVEQLKAQLAKKEKEQQQSARGASGENasgmgtqSEAVGK 1123
Cdd:pfam05483  421 LDEKKQFEKIAEELKGKEQELIFLLQAREKEIHDLEIQLTAIKTSEEHYLKEVEDLKTELEKEKLKN-------IELTAH 493

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 861483604  1124 MEALRAKVSKLEQQCQQQQEEADSLARSLESERAFHVERDRALETLQGQLEEKARELGYSQAASASAQRELATLRAKAQD 1203
Cdd:pfam05483  494 CDKLLLENKELTQEASDMTLELKKHQEDIINCKKQEERMLKQIENLEEKEMNLRDELESVREEFIQKGDEVKCKLDKSEE 573

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 861483604  1204 HSKAEEewkAQVARGQQEAVRKGSLISSLEEEVSILNRQVLEKEGESKELKRLVIAESEKSQKLEERLRLLQMETASNSA 1283
Cdd:pfam05483  574 NARSIE---YEVLKKEKQMKILENKCNNLKKQIENKNKNIEELHQENKALKKKGSAENKQLNAYEIKVNKLELELASAKQ 650

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 861483604  1284 RAAERSSALREEV-------QSLREEVEKQRAASE---NLRQELASQAER-------------------AEELGQELKAW 1334
Cdd:pfam05483  651 KFEEIIDNYQKEIedkkiseEKLLEEVEKAKAIADeavKLQKEIDKRCQHkiaemvalmekhkhqydkiIEERDSELGLY 730

                          730       740       750       760       770
                   ....*....|....*....|....*....|....*....|....*....|....*.
gi 861483604  1335 QEKFFQKEQALSALQLEHTSTQAlvsELLPAKhlcQQLQAEQVAAEKRHREELEQS 1390
Cdd:pfam05483  731 KNKEQEQSSAKAALEIELSNIKA---ELLSLK---KQLEIEKEEKEKLKMEAKENT 780
PRK10929 PRK10929
putative mechanosensitive channel protein; Provisional
 216-518 2.84e-04

putative mechanosensitive channel protein; Provisional


Pssm-ID: 236798 [Multi-domain]  Cd Length: 1109  Bit Score: 46.20  E-value: 2.84e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 861483604  216 MRRLKKQLADERNNR---------DELELELAEHRKLLTEKDAQISMMQQRI----DRLALLNEKQAASPLEPRELE-EL 281
Cdd:PRK10929   81 SAELRQQLNNERDEPrsvppnmstDALEQEILQVSSQLLEKSRQAQQEQDRAreisDSLSQLPQQQTEARRQLNEIErRL 160

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 861483604  282 RGKNESLTfrlheTLKQCQD--LKTEKGQMDRKIN-----QLSEEN--------GDLSFKLREFASN-LQQLQGALNEL- 344
Cdd:PRK10929  161 QTLGTPNT-----PLAQAQLtaLQAESAALKALVDelelaQLSANNrqelarlrSELAKKRSQQLDAyLQALRNQLNSQr 235

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 861483604  345 ---TEEHSKATQQWVEKQAHLEKELSTALQdkkcleeKNEILQGKLSQLEERLAQLPESPRQEKGEVLGDVLQLESLKQE 421
Cdd:PRK10929  236 qreAERALESTELLAEQSGDLPKSIVAQFK-------INRELSQALNQQAQRMDLIASQQRQAASQTLQVRQALNTLREQ 308

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 861483604  422 AATLATNNT---QLQARV----EMLENEQGQKE-AQLLGERSHFEEEKQQLASLITNLQSSISNLSQAKEELEQAS-QAQ 492
Cdd:PRK10929  309 SQWLGVSNAlgeALRAQVarlpEMPKPQQLDTEmAQLRVQRLRYEDLLNKQPQLRQIRQADGQPLTAEQNRILDAQlRTQ 388

                         330       340       350
                  ....*....|....*....|....*....|
gi 861483604  493 GAKLNAQVA---SLTAELTTLS-ATLQQQD 518
Cdd:PRK10929  389 RELLNSLLSggdTLILELTKLKvANSQLED 418
CCDC158 pfam15921
Coiled-coil domain-containing protein 158; CCDC158 is a family of proteins found in eukaryotes. ...
 218-758 3.04e-04

Coiled-coil domain-containing protein 158; CCDC158 is a family of proteins found in eukaryotes. The function is not known.


Pssm-ID: 464943 [Multi-domain]  Cd Length: 1112  Bit Score: 46.26  E-value: 3.04e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 861483604   218 RLKKQLADERNNRDELELElAEHRKLLTEKDAQISMMqqrIDRLAllnekqaasplepRELEELRGKNESLTFRLHETLK 297
Cdd:pfam15921  378 QLQKLLADLHKREKELSLE-KEQNKRLWDRDTGNSIT---IDHLR-------------RELDDRNMEVQRLEALLKAMKS 440

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 861483604   298 QCQdlktekGQMDRKINQLSEENGDLSfKLREFASNLQQLQGALNELTEEHSkATQQWVEKQAHLEKELSTALQDK-KCL 376
Cdd:pfam15921  441 ECQ------GQMERQMAAIQGKNESLE-KVSSLTAQLESTKEMLRKVVEELT-AKKMTLESSERTVSDLTASLQEKeRAI 512

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 861483604   377 EEKNEILQGKLSQLEERLAQLPESPRQEKgevlgdvlQLESLKQEAATLATNNTQLQARVEMLEnEQGQKEAQLLGERSH 456
Cdd:pfam15921  513 EATNAEITKLRSRVDLKLQELQHLKNEGD--------HLRNVQTECEALKLQMAEKDKVIEILR-QQIENMTQLVGQHGR 583

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 861483604   457 ----FEEEKQQLASLITNLQSSISNLSQAKEEleqaSQAQGAKLNAQVASLTAE-----------LTTLSATLQQQDQEL 521
Cdd:pfam15921  584 tagaMQVEKAQLEKEINDRRLELQEFKILKDK----KDAKIRELEARVSDLELEkvklvnagserLRAVKDIKQERDQLL 659

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 861483604   522 aglkQQAQKKQAQLAQSLQQQEQASQGLRHQVEQLSGSLKQKEKQLEEAARELDASRRDHAQQLATAAKAQETSLRERda 601
Cdd:pfam15921  660 ----NEVKTSRNELNSLSEDYEVLKRNFRNKSEEMETTTNKLKMQLKSAQSELEQTRNTLKSMEGSDGHAMKVAMGMQ-- 733

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 861483604   602 acQQLEAlekeKAAKLEILQQQLQAANEAQDSAQNSVTQAQREKAELSQKVEELhalieaahqeqceaqtqvaalearlk 681
Cdd:pfam15921  734 --KQITA----KRGQIDALQSKIQFLEEAMTNANKEKHFLKEEKNKLSQELSTV-------------------------- 781

                          490       500       510       520       530       540       550
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 861483604   682 aeqqkATEREKVAQEKAQLQEQlwslEESLKITKGSLEEEKCRAAAALEEHQHHISEMEAESRSLAEQHKQERKELE 758
Cdd:pfam15921  782 -----ATEKNKMAGELEVLRSQ----ERRLKEKVANMEVALDKASLQFAECQDIIQRQEQESVRLKLQHTLDVKELQ 849
SMC_prok_B TIGR02168
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...
 1526-1733 3.04e-04

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274008 [Multi-domain]  Cd Length: 1179  Bit Score: 46.20  E-value: 3.04e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 861483604  1526 QRFQEERQKLTAQVEQLEVFQREQTKKVEELSKKLADYDQASKVQQQKLKAFQAQGGESQQEAQRLQTQLNELQVQLSQK 1605
Cdd:TIGR02168  221 ELRELELALLVLRLEELREELEELQEELKEAEEELEELTAELQELEEKLEELRLEVSELEEEIEELQKELYALANEISRL 300

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 861483604  1606 EQAAEHYKVQMEKAKTHYDAKKQQNQELQ----EQLQGLEQLQKENKELRAEAERLGQELQQAGLKTKEAEQTCRHLTAQ 1681
Cdd:TIGR02168  301 EQQKQILRERLANLERQLEELEAQLEELEskldELAEELAELEEKLEELKEELESLEAELEELEAELEELESRLEELEEQ 380

                          170       180       190       200       210
                   ....*....|....*....|....*....|....*....|....*....|..
gi 861483604  1682 VRSLEAQVAHADQQLRELGKFQVASDALKSREPQAKPQLDLSIDSLDLSCEE 1733
Cdd:TIGR02168  381 LETLRSKVAQLELQIASLNNEIERLEARLERLEDRRERLQQEIEELLKKLEE 432
CCDC158 pfam15921
Coiled-coil domain-containing protein 158; CCDC158 is a family of proteins found in eukaryotes. ...
 1173-1716 3.31e-04

Coiled-coil domain-containing protein 158; CCDC158 is a family of proteins found in eukaryotes. The function is not known.


Pssm-ID: 464943 [Multi-domain]  Cd Length: 1112  Bit Score: 45.88  E-value: 3.31e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 861483604  1173 LEEKARElGYSQAASASAQRELATLRAKAQD-----HSKAEEEWKAQVARGQQEAVRK-GSLISSLEEEVSILNRQVLEK 1246
Cdd:pfam15921  283 LTEKASS-ARSQANSIQSQLEIIQEQARNQNsmymrQLSDLESTVSQLRSELREAKRMyEDKIEELEKQLVLANSELTEA 361

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 861483604  1247 EGESKELKRLVIAESEKSQKL----EERLRLLQMETASNSaRAAERSSA-------LREEVQSLREEVEKQRAASENLRQ 1315
Cdd:pfam15921  362 RTERDQFSQESGNLDDQLQKLladlHKREKELSLEKEQNK-RLWDRDTGnsitidhLRRELDDRNMEVQRLEALLKAMKS 440

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 861483604  1316 ELASQAER--------------AEELGQELKAWQEKFFQKEQALSALQLEHTSTQALVSELLPAKHLCQQLQAEQVAAEK 1381
Cdd:pfam15921  441 ECQGQMERqmaaiqgkneslekVSSLTAQLESTKEMLRKVVEELTAKKMTLESSERTVSDLTASLQEKERAIEATNAEIT 520

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 861483604  1382 RHREELEQSKQAAGGLRTELMRAQRELGELVPLRQKVAEQERAAQQLRAEkasyAEQLSMLKKAHGLLAeeNRGLGERAN 1461
Cdd:pfam15921  521 KLRSRVDLKLQELQHLKNEGDHLRNVQTECEALKLQMAEKDKVIEILRQQ----IENMTQLVGQHGRTA--GAMQVEKAQ 594

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 861483604  1462 LGRQFLEVELDqarekyIQELAAVRGDAETRLAEMRQEVQstthELEVMTAKYEGAKVKVLEERQRFQEERQKLTAQVEQ 1541
Cdd:pfam15921  595 LEKEINDRRLE------LQEFKILKDKKDAKIRELEARVS----DLELEKVKLVNAGSERLRAVKDIKQERDQLLNEVKT 664

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 861483604  1542 LEVFQREQTKKVEELSKKLADYDQASKVQQQKLKAfqaQGGESQQEAQRLQTQLNELQVQLSQKEQAAEHYKVQMEKAKT 1621
Cdd:pfam15921  665 SRNELNSLSEDYEVLKRNFRNKSEEMETTTNKLKM---QLKSAQSELEQTRNTLKSMEGSDGHAMKVAMGMQKQITAKRG 741

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 861483604  1622 HYDAkkqQNQELQEQLQGLEQLQKENKELRAEAERLGQELQQAGLKTKEAEQTCRHLTAQVRSLEAQVAHADQQLRELG- 1700
Cdd:pfam15921  742 QIDA---LQSKIQFLEEAMTNANKEKHFLKEEKNKLSQELSTVATEKNKMAGELEVLRSQERRLKEKVANMEVALDKASl 818

                          570
                   ....*....|....*.
gi 861483604  1701 KFQVASDALKSREPQA 1716
Cdd:pfam15921  819 QFAECQDIIQRQEQES 834
YhaN COG4717
Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown];
898-1335 3.34e-04

Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown];


Pssm-ID: 443752 [Multi-domain]  Cd Length: 641  Bit Score: 45.91  E-value: 3.34e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 861483604  898 DDLSTLQEKMAATSKEVARLEALVRKagEQQETASLELLKEPPKTRDRESEWVEEQQgqQLCSTQAALRAMEREAEQMGT 977
Cdd:COG4717    71 KELKELEEELKEAEEKEEEYAELQEE--LEELEEELEELEAELEELREELEKLEKLL--QLLPLYQELEALEAELAELPE 146

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 861483604  978 ELEKLRAALMESQGQQQEERGQQerevARLTQERGQAEADLALEKAAKAELEMRLQNALNEQQAEFANLQEALSRALSEK 1057
Cdd:COG4717   147 RLEELEERLEELRELEEELEELE----AELAELQEELEELLEQLSLATEEELQDLAEELEELQQRLAELEEELEEAQEEL 222

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 861483604 1058 EGKDQELSKLceqeaVQRMELKELLQTVEQLKAQLAkkekeqqqSARGASGENASGMGTQSEAVGKMEALRAKVSKLEQQ 1137
Cdd:COG4717   223 EELEEELEQL-----ENELEAAALEERLKEARLLLL--------IAAALLALLGLGGSLLSLILTIAGVLFLVLGLLALL 289

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 861483604 1138 CQQQQEEADSLARSLESERAFHVERDRALETLQGQLEEKARELGYSQAASASAQRELATLRAKAQDHSKAEEEWKAQVAR 1217
Cdd:COG4717   290 FLLLAREKASLGKEAEELQALPALEELEEEELEELLAALGLPPDLSPEELLELLDRIEELQELLREAEELEEELQLEELE 369

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 861483604 1218 GQQEAVRKGSLISSLEEEVSILN--RQVLEKEGESKELKRLVIAESEKSQKLEERLRLLQMETASNSARAA-----ERSS 1290
Cdd:COG4717   370 QEIAALLAEAGVEDEEELRAALEqaEEYQELKEELEELEEQLEELLGELEELLEALDEEELEEELEELEEEleeleEELE 449

                         410       420       430       440
                  ....*....|....*....|....*....|....*....|....*
gi 861483604 1291 ALREEVQSLREEVEkQRAASENLRQELASQAERAEELGQELKAWQ 1335
Cdd:COG4717   450 ELREELAELEAELE-QLEEDGELAELLQELEELKAELRELAEEWA 493
Myosin_tail_1 pfam01576
Myosin tail; The myosin molecule is a multi-subunit complex made up of two heavy chains and ...
 210-906 3.58e-04

Myosin tail; The myosin molecule is a multi-subunit complex made up of two heavy chains and four light chains it is a fundamental contractile protein found in all eukaryote cell types. This family consists of the coiled-coil myosin heavy chain tail region. The coiled-coil is composed of the tail from two molecules of myosin. These can then assemble into the macromolecular thick filament. The coiled-coil region provides the structural backbone the thick filament.


Pssm-ID: 460256 [Multi-domain]  Cd Length: 1081  Bit Score: 45.94  E-value: 3.58e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 861483604   210 QTPQFQMRRLKKQLADERNNRDELELELAE--HRKLLTEKDAQISMMQQRIDRLALLNEKQAASPLEPRELEELRGKNES 287
Cdd:pfam01576    3 QEEEMQAKEEELQKVKERQQKAESELKELEkkHQQLCEEKNALQEQLQAETELCAEAEEMRARLAARKQELEEILHELES 82

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 861483604   288 ltfRLHETLKQCQDLKTEKGQMDRKI----NQLSEENG----------DLSFKLREFASNLQQLQGALNELTEEHSKATQ 353
Cdd:pfam01576   83 ---RLEEEEERSQQLQNEKKKMQQHIqdleEQLDEEEAarqklqlekvTTEAKIKKLEEDILLLEDQNSKLSKERKLLEE 159

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 861483604   354 QWVEKQAHLEKELSTALQDKKcLEEKNEILqgkLSQLEERLAqlpespRQEKGEvlgdvLQLESLKQ----EAATLATNN 429
Cdd:pfam01576  160 RISEFTSNLAEEEEKAKSLSK-LKNKHEAM---ISDLEERLK------KEEKGR-----QELEKAKRklegESTDLQEQI 224

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 861483604   430 TQLQARVEMLENEQGQKEAQLLGERSHFEEEKQQLASLITNLQSSISNLSQAKEELEQASQAQgAKLNAQVASLTAELTT 509
Cdd:pfam01576  225 AELQAQIAELRAQLAKKEEELQAALARLEEETAQKNNALKKIRELEAQISELQEDLESERAAR-NKAEKQRRDLGEELEA 303

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 861483604   510 LSATLQQQDQELAGLKQqaqkkqaqlaqslqqqeqasqgLRHQVEQLSGSLKqkeKQLEEAARELDAS----RRDHAQQL 585
Cdd:pfam01576  304 LKTELEDTLDTTAAQQE----------------------LRSKREQEVTELK---KALEEETRSHEAQlqemRQKHTQAL 358

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 861483604   586 ATAAKAQETSLRERDAACQQLEALEKEKAAkleiLQQQLQAANEAQdsaqnsvTQAQREKAELSQKVEELHALIEAAHQE 665
Cdd:pfam01576  359 EELTEQLEQAKRNKANLEKAKQALESENAE----LQAELRTLQQAK-------QDSEHKRKKLEGQLQELQARLSESERQ 427

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 861483604   666 QCEAQTQVAALEARLKAEQQKATEREKvaqEKAQLQEQLWSLEESLKITKGSLEEEKcRAAAALeehQHHISEMEAESRS 745
Cdd:pfam01576  428 RAELAEKLSKLQSELESVSSLLNEAEG---KNIKLSKDVSSLESQLQDTQELLQEET-RQKLNL---STRLRQLEDERNS 500

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 861483604   746 LAEQhkqerkeLEEEKAKRRGLGVQLQqlaeTHQAETKALRQELAKARTSNNMAEREVELLVKEVKTWRKRYEDSQQGET 825
Cdd:pfam01576  501 LQEQ-------LEEEEEAKRNVERQLS----TLQAQLSDMKKKLEEDAGTLEALEEGKKRLQRELEALTQQLEEKAAAYD 569

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 861483604   826 QygLQEQLTTLKEEYEKSCQELRETKEKMAGIEAHSElQIGQHQSELAQLHANLA----RALQQVQEKENRAQKLADDLS 901
Cdd:pfam01576  570 K--LEKTKNRLQQELDDLLVDLDHQRQLVSNLEKKQK-KFDQMLAEEKAISARYAeerdRAEAEAREKETRALSLARALE 646


                   ....*
gi 861483604   902 TLQEK 906
Cdd:pfam01576  647 EALEA 651
DR0291 COG1579
Predicted nucleic acid-binding protein DR0291, contains C4-type Zn-ribbon domain [General ...
 596-769 3.69e-04

Predicted nucleic acid-binding protein DR0291, contains C4-type Zn-ribbon domain [General function prediction only];


Pssm-ID: 441187 [Multi-domain]  Cd Length: 236  Bit Score: 44.15  E-value: 3.69e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 861483604  596 LRERDAACQQLEALEKEKAAKLEILQQQLQAANEAQDSAQNSVTQAQREKAELSQKVEELHALIEAAHQEQCEAQT--QV 673
Cdd:COG1579    12 LQELDSELDRLEHRLKELPAELAELEDELAALEARLEAAKTELEDLEKEIKRLELEIEEVEARIKKYEEQLGNVRNnkEY 91

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 861483604  674 AALE---ARLKAEQQKATEREKVAQEKA-QLQEQLWSLEESLKITKGSLEEEKCRAAAALEEHQHHISEMEAESRSLAEQ 749
Cdd:COG1579    92 EALQkeiESLKRRISDLEDEILELMERIeELEEELAELEAELAELEAELEEKKAELDEELAELEAELEELEAEREELAAK 171

                         170       180
                  ....*....|....*....|.
gi 861483604  750 HKQERKEL-EEEKAKRRGLGV 769
Cdd:COG1579   172 IPPELLALyERIRKRKNGLAV 192
PRK03918 PRK03918
DNA double-strand break repair ATPase Rad50;
1077-1672 3.72e-04

DNA double-strand break repair ATPase Rad50;


Pssm-ID: 235175 [Multi-domain]  Cd Length: 880  Bit Score: 45.83  E-value: 3.72e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 861483604 1077 ELKELLQTVEQLKAQLAKKEKEQQQSARGASgenasgmgtqsEAVGKMEALRAKVSKLEQQCQQQQEEADSLArSLESER 1156
Cdd:PRK03918  180 RLEKFIKRTENIEELIKEKEKELEEVLREIN-----------EISSELPELREELEKLEKEVKELEELKEEIE-ELEKEL 247

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 861483604 1157 AFHVERDRALETLQGQLEEKARELGYSQAASASAQRELATLRAKAQDHSKAEEEWKAQVARGQQEAVRKgsliSSLEEEV 1236
Cdd:PRK03918  248 ESLEGSKRKLEEKIRELEERIEELKKEIEELEEKVKELKELKEKAEEYIKLSEFYEEYLDELREIEKRL----SRLEEEI 323

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 861483604 1237 SILNRQVLEKEGESKELKRLviaeSEKSQKLEERLRLLQmetasNSARAAERSSALREEVQSLREEVEKQraASENLRQE 1316
Cdd:PRK03918  324 NGIEERIKELEEKEERLEEL----KKKLKELEKRLEELE-----ERHELYEEAKAKKEELERLKKRLTGL--TPEKLEKE 392

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 861483604 1317 LASQAERAEELGQELKAWQEKffqkeqaLSALQLEHTSTQALVSELLPAKHLC--------QQLQAEQVAAEKRHREELE 1388
Cdd:PRK03918  393 LEELEKAKEEIEEEISKITAR-------IGELKKEIKELKKAIEELKKAKGKCpvcgreltEEHRKELLEEYTAELKRIE 465

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 861483604 1389 QSKQAAGGLRTELMRAQRELGELVPLRQKVAEQERAAQQLRAEKASYAE-QLSMLKKAhgllAEENRGLGERAN-LGRQF 1466
Cdd:PRK03918  466 KELKEIEEKERKLRKELRELEKVLKKESELIKLKELAEQLKELEEKLKKyNLEELEKK----AEEYEKLKEKLIkLKGEI 541

                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 861483604 1467 LEVELDQAREK-YIQELAAVrgdaETRLAEMRQEVQSTTHELEVMTAKYEGAKVKVLEERQRFQEERQKLTAQVEQLEVF 1545
Cdd:PRK03918  542 KSLKKELEKLEeLKKKLAEL----EKKLDELEEELAELLKELEELGFESVEELEERLKELEPFYNEYLELKDAEKELERE 617

                         490       500       510       520       530       540       550       560
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 861483604 1546 QREQTKKVEELSKKLADYDQASKvqqqklkafqaqggesqqEAQRLQTQLNELQVQLSQKEqaaehykvqmekakthYDA 1625
Cdd:PRK03918  618 EKELKKLEEELDKAFEELAETEK------------------RLEELRKELEELEKKYSEEE----------------YEE 663

                         570       580       590       600
                  ....*....|....*....|....*....|....*....|....*..
gi 861483604 1626 KKQQNQELQEQLQGLEQLQKENKELRAEAERLGQELQQAGLKTKEAE 1672
Cdd:PRK03918  664 LREEYLELSRELAGLRAELEELEKRREEIKKTLEKLKEELEEREKAK 710
mukB PRK04863
chromosome partition protein MukB;
1276-1708 4.35e-04

chromosome partition protein MukB;


Pssm-ID: 235316 [Multi-domain]  Cd Length: 1486  Bit Score: 45.72  E-value: 4.35e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 861483604 1276 METASNSARAAERSSALREEVQSLREEVEKQRAASENLRQELASQAERAEELGQELKAWQEKFfQKEQALSALQLEHTST 1355
Cdd:PRK04863  275 MRHANERRVHLEEALELRRELYTSRRQLAAEQYRLVEMARELAELNEAESDLEQDYQAASDHL-NLVQTALRQQEKIERY 353

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 861483604 1356 QALVSELLPAkhLCQQLQAEQVAAEKR--HREELEQSKQAAGGLRTELMRAQRELGELvplrQKVAEQERAAQQLraeka 1433
Cdd:PRK04863  354 QADLEELEER--LEEQNEVVEEADEQQeeNEARAEAAEEEVDELKSQLADYQQALDVQ----QTRAIQYQQAVQA----- 422

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 861483604 1434 syaeqlsmLKKAHGLLaeenrglgeranlgrQFLEVELDQArEKYIQELAAVRGDAETRLAEMRQEVQSTTHELEVMTAK 1513
Cdd:PRK04863  423 --------LERAKQLC---------------GLPDLTADNA-EDWLEEFQAKEQEATEELLSLEQKLSVAQAAHSQFEQA 478

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 861483604 1514 YEGAKVKVLE-ERQRFQEERQKLTAQVEQlevfQREQTKKVEELSKKLADYDQASKVQQQKLKAFQaqggESQQEAQRLQ 1592
Cdd:PRK04863  479 YQLVRKIAGEvSRSEAWDVARELLRRLRE----QRHLAEQLQQLRMRLSELEQRLRQQQRAERLLA----EFCKRLGKNL 550

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 861483604 1593 TQLNELQVQLSQKEQAAEHYKVQMEKAKTHYDAKKQQNQELQEQLQGLEQLQKENKELRAEAERLG----------QELQ 1662
Cdd:PRK04863  551 DDEDELEQLQEELEARLESLSESVSEARERRMALRQQLEQLQARIQRLAARAPAWLAAQDALARLReqsgeefedsQDVT 630

                         410       420       430       440
                  ....*....|....*....|....*....|....*....|....*.
gi 861483604 1663 QAGLKTKEAEqtcRHLTAQVRSLEAQVAHADQQLRELGKFQVASDA 1708
Cdd:PRK04863  631 EYMQQLLERE---RELTVERDELAARKQALDEEIERLSQPGGSEDP 673
EnvC COG4942
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, ...
 552-763 4.73e-04

Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 443969 [Multi-domain]  Cd Length: 377  Bit Score: 44.75  E-value: 4.73e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 861483604  552 QVEQLSGSLKQKEKQLEEAARELDASRRDHAQQLATAAKAQETSLRERDAACQQLEALEKEKAAKLEILQQQLQAANEAQ 631
Cdd:COG4942    38 ELEKELAALKKEEKALLKQLAALERRIAALARRIRALEQELAALEAELAELEKEIAELRAELEAQKEELAELLRALYRLG 117

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 861483604  632 DSAQNSVTQAQREKAELSQKVEELHALIEAAHQEQCEAQTQVAALEARlkaEQQKATEREKVAQEKAQLQEQLWSLEESL 711
Cdd:COG4942   118 RQPPLALLLSPEDFLDAVRRLQYLKYLAPARREQAEELRADLAELAAL---RAELEAERAELEALLAELEEERAALEALK 194

                         170       180       190       200       210
                  ....*....|....*....|....*....|....*....|....*....|..
gi 861483604  712 KITKGSLEeekcRAAAALEEHQHHISEMEAESRSLAEQHKQERKELEEEKAK 763
Cdd:COG4942   195 AERQKLLA----RLEKELAELAAELAELQQEAEELEALIARLEAEAAAAAER 242
PRK11281 PRK11281
mechanosensitive channel MscK;
228-521 6.11e-04

mechanosensitive channel MscK;


Pssm-ID: 236892 [Multi-domain]  Cd Length: 1113  Bit Score: 45.29  E-value: 6.11e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 861483604  228 NNRDELELELAEHRKLLTEKDAQISMMQQRIDRLALLNEKQAASPLEPRELEELrgknESltfRLHETLKQCQDLKtekg 307
Cdd:PRK11281   73 DKIDRQKEETEQLKQQLAQAPAKLRQAQAELEALKDDNDEETRETLSTLSLRQL----ES---RLAQTLDQLQNAQ---- 141

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 861483604  308 qmdrkiNQLSEENGDLsfklrefaSNLQ-QLQGALNELTeEHSKATQQwvekqahLEKELSTALQDKKCL--EEKNEiLQ 384
Cdd:PRK11281  142 ------NDLAEYNSQL--------VSLQtQPERAQAALY-ANSQRLQQ-------IRNLLKGGKVGGKALrpSQRVL-LQ 198

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 861483604  385 GKLSQLEerlaqlpesprqekgevlgdvLQLESLKQEAAtlatNNTQLQarvemlenEQGQKEAQLLGERShfeeekQQL 464
Cdd:PRK11281  199 AEQALLN---------------------AQNDLQRKSLE----GNTQLQ--------DLLQKQRDYLTARI------QRL 239

                         250       260       270       280       290       300
                  ....*....|....*....|....*....|....*....|....*....|....*....|..
gi 861483604  465 ASLITNLQSSIS--NLSQAKEELEQASQAQGA---KLNAQVASLTAELTTLSATLQQQDQEL 521
Cdd:PRK11281  240 EHQLQLLQEAINskRLTLSEKTVQEAQSQDEAariQANPLVAQELEINLQLSQRLLKATEKL 301
YhaN COG4717
Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown];
960-1451 6.31e-04

Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown];


Pssm-ID: 443752 [Multi-domain]  Cd Length: 641  Bit Score: 44.76  E-value: 6.31e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 861483604  960 STQAALRAM-EREAEQMGTELEKLRAALMESQGQQQEERGQQEREVARLTQERGQAEADLALEKAAKAELEMRLQNAlnE 1038
Cdd:COG4717    38 TLLAFIRAMlLERLEKEADELFKPQGRKPELNLKELKELEEELKEAEEKEEEYAELQEELEELEEELEELEAELEEL--R 115

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 861483604 1039 QQAEFANLQEALSRALSEKEGKDQELSKLCEQEAVQRMELKELLQTVEQLKAQLAKKEKEQQQSARGASGENASGMGTQS 1118
Cdd:COG4717   116 EELEKLEKLLQLLPLYQELEALEAELAELPERLEELEERLEELRELEEELEELEAELAELQEELEELLEQLSLATEEELQ 195

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 861483604 1119 EAVGKMEALRAKVSKLEQQCQQQQEEADSLARSLESERAfhverdralETLQGQLEEKARELGYSQAASASaqreLATLR 1198
Cdd:COG4717   196 DLAEELEELQQRLAELEEELEEAQEELEELEEELEQLEN---------ELEAAALEERLKEARLLLLIAAA----LLALL 262

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 861483604 1199 AKAQDHSKAEEEWKAQVArgqqeavrkgSLISSLEEEVSILNRQVLEKEGESKELKRLVIAESEKSQKLEERLRLLQMET 1278
Cdd:COG4717   263 GLGGSLLSLILTIAGVLF----------LVLGLLALLFLLLAREKASLGKEAEELQALPALEELEEEELEELLAALGLPP 332

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 861483604 1279 ASNSARAAERSSALrEEVQSLREEVEKQRAASENLRQELASQAERAEELGQELKAWQEKFFQKEQALSALQLEHTSTQAL 1358
Cdd:COG4717   333 DLSPEELLELLDRI-EELQELLREAEELEEELQLEELEQEIAALLAEAGVEDEEELRAALEQAEEYQELKEELEELEEQL 411

                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 861483604 1359 VSELLPAKHLCQQLQAEQVAAEKRH-REELEQSKQAAGGLRTELMRAQRELGELVPlRQKVAEQERAAQQLRAEKASYAE 1437
Cdd:COG4717   412 EELLGELEELLEALDEEELEEELEElEEELEELEEELEELREELAELEAELEQLEE-DGELAELLQELEELKAELRELAE 490

                         490
                  ....*....|....
gi 861483604 1438 QLSMLKKAHGLLAE 1451
Cdd:COG4717   491 EWAALKLALELLEE 504
sbcc TIGR00618
exonuclease SbcC; All proteins in this family for which functions are known are part of an ...
 969-1658 6.77e-04

exonuclease SbcC; All proteins in this family for which functions are known are part of an exonuclease complex with sbcD homologs. This complex is involved in the initiation of recombination to regulate the levels of palindromic sequences in DNA. This family is based on the phylogenomic analysis of JA Eisen (1999, Ph.D. Thesis, Stanford University). [DNA metabolism, DNA replication, recombination, and repair]


Pssm-ID: 129705 [Multi-domain]  Cd Length: 1042  Bit Score: 44.96  E-value: 6.77e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 861483604   969 EREAEQMGTELEKLRAALMESQGQQQEERGQQEREVARLTQERGQAEADLALEKAAKAELEMRLQNALNEQQA---EFAN 1045
Cdd:TIGR00618  195 KAELLTLRSQLLTLCTPCMPDTYHERKQVLEKELKHLREALQQTQQSHAYLTQKREAQEEQLKKQQLLKQLRArieELRA 274

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 861483604  1046 LQEALSRALSEKEGKDQELSKLCEQEAVQRMElKELLQTVEQLKAQLAKKEKEQQQSARGASGENASGMGTQSEavgkmE 1125
Cdd:TIGR00618  275 QEAVLEETQERINRARKAAPLAAHIKAVTQIE-QQAQRIHTELQSKMRSRAKLLMKRAAHVKQQSSIEEQRRLL-----Q 348

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 861483604  1126 ALRAKVSKLEQQCQQQQEEADSLARSLESERAFHVERDRaLETLQGQLEEKARELGYSQAASASAQRELATLRAKAQDHS 1205
Cdd:TIGR00618  349 TLHSQEIHIRDAHEVATSIREISCQQHTLTQHIHTLQQQ-KTTLTQKLQSLCKELDILQREQATIDTRTSAFRDLQGQLA 427

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 861483604  1206 KAEEEWKAQVARGQQEAVRKGSLISSLEEEVSILNR---QVLEKEGESKELKRLVIAESEKSQKLEERLRLLQMETA--- 1279
Cdd:TIGR00618  428 HAKKQQELQQRYAELCAAAITCTAQCEKLEKIHLQEsaqSLKEREQQLQTKEQIHLQETRKKAVVLARLLELQEEPCplc 507

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 861483604  1280 ------SNSARAAERSSALREEVQSLREEVEKQRAASENLRQELASQAERAEELGQELKAWQEKFFQKEQALSALQLEHT 1353
Cdd:TIGR00618  508 gscihpNPARQDIDNPGPLTRRMQRGEQTYAQLETSEEDVYHQLTSERKQRASLKEQMQEIQQSFSILTQCDNRSKEDIP 587

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 861483604  1354 STQALVSELLPakHLCQQLQAEQVAAEKRHREELEQSKQAAGgLRTELMRAQRELGELVPLRQKVAEQERAAQQLRAEKA 1433
Cdd:TIGR00618  588 NLQNITVRLQD--LTEKLSEAEDMLACEQHALLRKLQPEQDL-QDVRLHLQQCSQELALKLTALHALQLTLTQERVREHA 664

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 861483604  1434 SYAEQLSMLKKAHGLLAEENRglgeranlgrQFLEVELDQAREKYIQELAAVRgDAETRLAEMRQEVQSTTHELEVMTAK 1513
Cdd:TIGR00618  665 LSIRVLPKELLASRQLALQKM----------QSEKEQLTYWKEMLAQCQTLLR-ELETHIEEYDREFNEIENASSSLGSD 733

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 861483604  1514 YEGAKVKVLEERQRFQEERQKLTAQVEQLEVFQREQTKKVEELSKKLADYDQASKVQQQKLKAFQAQGGESQQE-AQRLQ 1592
Cdd:TIGR00618  734 LAAREDALNQSLKELMHQARTVLKARTEAHFNNNEEVTAALQTGAELSHLAAEIQFFNRLREEDTHLLKTLEAEiGQEIP 813

                          650       660       670       680       690       700
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 861483604  1593 TQLNELQVQLSQKEQAAEHYKVQMEKAKTHYDAKKQQNQELQEQLQGLEQLQKENKELRAEAERLG 1658
Cdd:TIGR00618  814 SDEDILNLQCETLVQEEEQFLSRLEEKSATLGEITHQLLKYEECSKQLAQLTQEQAKIIQLSDKLN 879
MukB COG3096
Chromosome condensin MukBEF, ATPase and DNA-binding subunit MukB [Cell cycle control, cell ...
 560-883 7.05e-04

Chromosome condensin MukBEF, ATPase and DNA-binding subunit MukB [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 442330 [Multi-domain]  Cd Length: 1470  Bit Score: 44.94  E-value: 7.05e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 861483604  560 LKQKEKQLEEAAREL---DASRRDHAQQLAtAAKAQETSLRerdAACQQLEALEKEK-AAKLEILQQQLQAANEAQDSAQ 635
Cdd:COG3096   838 LAALRQRRSELERELaqhRAQEQQLRQQLD-QLKEQLQLLN---KLLPQANLLADETlADRLEELREELDAAQEAQAFIQ 913

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 861483604  636 ---NSVTQAQREKAELS---QKVEELHALIEAAHQEQCEAQTQVAALEarlkaeqQKATEREKVA-QEKAQLQEQLWSLE 708
Cdd:COG3096   914 qhgKALAQLEPLVAVLQsdpEQFEQLQADYLQAKEQQRRLKQQIFALS-------EVVQRRPHFSyEDAVGLLGENSDLN 986

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 861483604  709 ESLKITKGSLEEEKCRAAAALEEHQHHISEMEAESRSLAEQHKQERKELEEEKAKRRGLGVQLQQLAE-THQAETKALRQ 787
Cdd:COG3096   987 EKLRARLEQAEEARREAREQLRQAQAQYSQYNQVLASLKSSRDAKQQTLQELEQELEELGVQADAEAEeRARIRRDELHE 1066

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 861483604  788 ELAKARTSNNMAEREVELLVKEVKTWRKRYedSQQGETQYGLQEQLTTLKEEYeksCQELRetkekmagIEAHSELQIGQ 867
Cdd:COG3096  1067 ELSQNRSRRSQLEKQLTRCEAEMDSLQKRL--RKAERDYKQEREQVVQAKAGW---CAVLR--------LARDNDVERRL 1133

                         330
                  ....*....|....*.
gi 861483604  868 HQSELAQLHANLARAL 883
Cdd:COG3096  1134 HRRELAYLSADELRSM 1149
Surf_Exclu_PgrA TIGR04320
SEC10/PgrA surface exclusion domain; This model describes a conserved domain found in surface ...
 617-712 7.56e-04

SEC10/PgrA surface exclusion domain; This model describes a conserved domain found in surface proteins of a number of Firmutes. Many members have LPXTG C-terminal anchoring motifs and a substantial number have the KxYKxGKxW putative sorting signal at the N-terminus. The tetracycline resistance plasmid pCF10 in Enterococcus faecalis promotes conjugal plasmid transfer in response to sex pheromones, but PgrA/Sec10 encoded by that plasmid, a member of this family, specifically inhibits the ability of cells to receive homologous plasmids. The phenomenon is called surface exclusion.


Pssm-ID: 275124 [Multi-domain]  Cd Length: 356  Bit Score: 43.95  E-value: 7.56e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 861483604   617 LEILQQQLQAANEAQDSAQNSVTQAQREKAELSQKVEELHALIEAAHQEQCEAQTQVAAL-EARLKAEQ---QKATEREK 692
Cdd:TIGR04320  256 LAALQAKLATAQADLAAAQTALNTAQAALTSAQTAYAAAQAALATAQKELANAQAQALQTaQNNLATAQaalANAEARLA 335

                           90       100
                   ....*....|....*....|.
gi 861483604   693 VAQEK-AQLQEQLWSLEESLK 712
Cdd:TIGR04320  336 KAKEAlANLNADLAKKQAALD 356
mukB PRK04863
chromosome partition protein MukB;
578-988 8.05e-04

chromosome partition protein MukB;


Pssm-ID: 235316 [Multi-domain]  Cd Length: 1486  Bit Score: 44.95  E-value: 8.05e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 861483604  578 RRDHAQQLATAAKAQETSLRERDAACQQLEALEKEKAAKLE---ILQQQLQAANEAQDSAQNSVTQAQREKaELSQKVEE 654
Cdd:PRK04863  281 RRVHLEEALELRRELYTSRRQLAAEQYRLVEMARELAELNEaesDLEQDYQAASDHLNLVQTALRQQEKIE-RYQADLEE 359

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 861483604  655 LHALIEAAHQEQCEAQTQVAALEARLKAEQQkaterekvaqEKAQLQEQLWSLEESLKI--TKGSLEEEkcrAAAALEEH 732
Cdd:PRK04863  360 LEERLEEQNEVVEEADEQQEENEARAEAAEE----------EVDELKSQLADYQQALDVqqTRAIQYQQ---AVQALERA 426

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 861483604  733 QHHISEMEAESRSLAEQHKQERKELEEEKAKRRGLGVQLQQLAETHQAETKALrqelAKARTSNNMAEREVellvkevkT 812
Cdd:PRK04863  427 KQLCGLPDLTADNAEDWLEEFQAKEQEATEELLSLEQKLSVAQAAHSQFEQAY----QLVRKIAGEVSRSE--------A 494

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 861483604  813 WRKRYEDSQQGETQYGLQEQLTtlkeeyekscqelretkekmagieahselQIGQHQSELAQLHANLARALQQVQEKENR 892
Cdd:PRK04863  495 WDVARELLRRLREQRHLAEQLQ-----------------------------QLRMRLSELEQRLRQQQRAERLLAEFCKR 545

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 861483604  893 AQKLADDLSTLQEKMAATSKEVARLEALVRKAGEQQET--ASLELLK-EPPKTRDRESEWVEEQQG-QQLCS-TQAALRA 967
Cdd:PRK04863  546 LGKNLDDEDELEQLQEELEARLESLSESVSEARERRMAlrQQLEQLQaRIQRLAARAPAWLAAQDAlARLREqSGEEFED 625

                         410       420
                  ....*....|....*....|.
gi 861483604  968 MEREAEQMGTELEKLRAALME 988
Cdd:PRK04863  626 SQDVTEYMQQLLERERELTVE 646
PRK05035 PRK05035
electron transport complex protein RnfC; Provisional
 590-793 8.95e-04

electron transport complex protein RnfC; Provisional


Pssm-ID: 235334 [Multi-domain]  Cd Length: 695  Bit Score: 44.55  E-value: 8.95e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 861483604  590 KAQETSLRERDAACQQLEA----LEKEKAAKLEILQQQLQA-ANEAQDSAQNSVTQAQREKAELSQKVEELH-------A 657
Cdd:PRK05035  439 RAIEQEKKKAEEAKARFEArqarLEREKAAREARHKKAAEArAAKDKDAVAAALARVKAKKAAATQPIVIKAgarpdnsA 518

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 861483604  658 LIEAAHQEQCEAQTQVAALEARLKAEQQKATEREKVAQEKAQLQEQLWSLEESLKIT---KGSLEEEKCRAAAALEEHQh 734
Cdd:PRK05035  519 VIAAREARKAQARARQAEKQAAAAADPKKAAVAAAIARAKAKKAAQQAANAEAEEEVdpkKAAVAAAIARAKAKKAAQQ- 597

                         170       180       190       200       210       220
                  ....*....|....*....|....*....|....*....|....*....|....*....|
gi 861483604  735 hISEMEAESRSLAEQHKQERKELEEEKAKRRGLGVQLQQLAETHQAETKA-LRQELAKAR 793
Cdd:PRK05035  598 -AASAEPEEQVAEVDPKKAAVAAAIARAKAKKAEQQANAEPEEPVDPRKAaVAAAIARAK 656
PRK03918 PRK03918
DNA double-strand break repair ATPase Rad50;
1284-1700 9.36e-04

DNA double-strand break repair ATPase Rad50;


Pssm-ID: 235175 [Multi-domain]  Cd Length: 880  Bit Score: 44.28  E-value: 9.36e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 861483604 1284 RAAERSSALREEVQSLREEVEKQRAASENLRQELASQAERAEELGQELKAWQEKFFQKEQALSALQLEHTSTQALVSELL 1363
Cdd:PRK03918  162 NAYKNLGEVIKEIKRRIERLEKFIKRTENIEELIKEKEKELEEVLREINEISSELPELREELEKLEKEVKELEELKEEIE 241

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 861483604 1364 PAKhlcqqlqaEQVAAEKRHREELEQSKQAAGGLRTELMRAQRELGELVPLRQKVAEQERAAQQLRAEKASYAEQLSMLK 1443
Cdd:PRK03918  242 ELE--------KELESLEGSKRKLEEKIRELEERIEELKKEIEELEEKVKELKELKEKAEEYIKLSEFYEEYLDELREIE 313

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 861483604 1444 KAHGLLAEENRGLGERANLGRQFLEV--ELDQAREKYIQELAAVRGDAET--RLAEMRQEVQSTTHELEVMTAKYEGAKV 1519
Cdd:PRK03918  314 KRLSRLEEEINGIEERIKELEEKEERleELKKKLKELEKRLEELEERHELyeEAKAKKEELERLKKRLTGLTPEKLEKEL 393

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 861483604 1520 KVLEERQR-FQEERQKLTAQVEQLEVFQREQTKKVEELSKK-------------------LADYDQASKVQQQKLKAFQA 1579
Cdd:PRK03918  394 EELEKAKEeIEEEISKITARIGELKKEIKELKKAIEELKKAkgkcpvcgrelteehrkelLEEYTAELKRIEKELKEIEE 473

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 861483604 1580 QGGESQQEAQRLQTQLNElQVQLSQKEQAAEHYKVQMEKAKThYDAKKQQNQELQeqlqgLEQLQKENKELRAEAERLGQ 1659
Cdd:PRK03918  474 KERKLRKELRELEKVLKK-ESELIKLKELAEQLKELEEKLKK-YNLEELEKKAEE-----YEKLKEKLIKLKGEIKSLKK 546

                         410       420       430       440
                  ....*....|....*....|....*....|....*....|.
gi 861483604 1660 ELQqaglKTKEAEQTCRHLTAQVRSLEAQVAHADQQLRELG 1700
Cdd:PRK03918  547 ELE----KLEELKKKLAELEKKLDELEEELAELLKELEELG 583
CwlO1 COG3883
Uncharacterized N-terminal coiled-coil domain of peptidoglycan hydrolase CwlO [Function ...
 469-699 9.64e-04

Uncharacterized N-terminal coiled-coil domain of peptidoglycan hydrolase CwlO [Function unknown];


Pssm-ID: 443091 [Multi-domain]  Cd Length: 379  Bit Score: 44.05  E-value: 9.64e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 861483604  469 TNLQSSISNLSQAKEELEQAsQAQGAKLNAQVASLTAELTTLSATLQQQDQELAGlkqqaqkkqaqlaqslqqqeqasqg 548
Cdd:COG3883    16 PQIQAKQKELSELQAELEAA-QAELDALQAELEELNEEYNELQAELEALQAEIDK------------------------- 69

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 861483604  549 LRHQVEQLSGSLKQKEKQLEEAARELDASRR------------------DHAQQLATAAKAQETSLRERDAACQQLEALE 610
Cdd:COG3883    70 LQAEIAEAEAEIEERREELGERARALYRSGGsvsyldvllgsesfsdflDRLSALSKIADADADLLEELKADKAELEAKK 149

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 861483604  611 KEKAAKLEILQQQLQAANEAQDSAQNSVTQAQREKAELSQKVEELHALIEAAHQEQCEAQTQVAALEARLKAEQQKATER 690
Cdd:COG3883   150 AELEAKLAELEALKAELEAAKAELEAQQAEQEALLAQLSAEEAAAEAQLAELEAELAAAEAAAAAAAAAAAAAAAAAAAA 229


                  ....*....
gi 861483604  691 EKVAQEKAQ 699
Cdd:COG3883   230 AAAAAAAAA 238
GumC COG3206
Exopolysaccharide export protein/domain GumC/Wzc1 [Cell wall/membrane/envelope biogenesis];
1148-1363 9.94e-04

Exopolysaccharide export protein/domain GumC/Wzc1 [Cell wall/membrane/envelope biogenesis];


Pssm-ID: 442439 [Multi-domain]  Cd Length: 687  Bit Score: 44.24  E-value: 9.94e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 861483604 1148 LARSLESERAfhvERDRALETLQGQLEEKARELgysqaasASAQRELATLRAKAQDHSKAEEewkAQVARGQQEAVRkgS 1227
Cdd:COG3206   162 LEQNLELRRE---EARKALEFLEEQLPELRKEL-------EEAEAALEEFRQKNGLVDLSEE---AKLLLQQLSELE--S 226

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 861483604 1228 LISSLEEEVSILNRQV--LEKEGESKELKRLVIAESEKSQKLEERLRLLQMETASNSARAAERSS---ALREEVQSLREE 1302
Cdd:COG3206   227 QLAEARAELAEAEARLaaLRAQLGSGPDALPELLQSPVIQQLRAQLAELEAELAELSARYTPNHPdviALRAQIAALRAQ 306

                         170       180       190       200       210       220
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 861483604 1303 VEKQ-RAASENLRQELASQAERAEELGQELKAWQEKFF---QKEQALSALQLEHTSTQALVSELL 1363
Cdd:COG3206   307 LQQEaQRILASLEAELEALQAREASLQAQLAQLEARLAelpELEAELRRLEREVEVARELYESLL 371
EnvC COG4942
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, ...
 288-523 1.17e-03

Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 443969 [Multi-domain]  Cd Length: 377  Bit Score: 43.60  E-value: 1.17e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 861483604  288 LTFRLHETLKQCQDLKTEKGQMDRKINQLSEENGDLSFKLREFASNLQQLQGALNELTEEHSKATQQwvekQAHLEKELS 367
Cdd:COG4942    11 LALAAAAQADAAAEAEAELEQLQQEIAELEKELAALKKEEKALLKQLAALERRIAALARRIRALEQE----LAALEAELA 86

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 861483604  368 TalqdkkcLEEKNEILQGKLSQLEERLA-QLPESPRQEKGEVLGDVLQLESLKQEAATLATNNTQLQARVEMLEnEQGQK 446
Cdd:COG4942    87 E-------LEKEIAELRAELEAQKEELAeLLRALYRLGRQPPLALLLSPEDFLDAVRRLQYLKYLAPARREQAE-ELRAD 158

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 861483604  447 EAQLLGERSHFEEEKQQLASLITNLQssisnlsQAKEELEQASQAQG---AKLNAQVASLTAELTTLSATLQQQDQELAG 523
Cdd:COG4942   159 LAELAALRAELEAERAELEALLAELE-------EERAALEALKAERQkllARLEKELAELAAELAELQQEAEELEALIAR 231
sbcc TIGR00618
exonuclease SbcC; All proteins in this family for which functions are known are part of an ...
 209-857 1.18e-03

exonuclease SbcC; All proteins in this family for which functions are known are part of an exonuclease complex with sbcD homologs. This complex is involved in the initiation of recombination to regulate the levels of palindromic sequences in DNA. This family is based on the phylogenomic analysis of JA Eisen (1999, Ph.D. Thesis, Stanford University). [DNA metabolism, DNA replication, recombination, and repair]


Pssm-ID: 129705 [Multi-domain]  Cd Length: 1042  Bit Score: 44.19  E-value: 1.18e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 861483604   209 LQTPQFQMRRLKKQLADERNNRDELELELAEHRKLltekdaqismmQQRIDRlallNEKQAASPLEPRELEELRGKNESL 288
Cdd:TIGR00618  248 KREAQEEQLKKQQLLKQLRARIEELRAQEAVLEET-----------QERINR----ARKAAPLAAHIKAVTQIEQQAQRI 312

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 861483604   289 TFRLHETlkqcqdlKTEKGQMDRKINQLSEENGDLSFKLRefasNLQQLQGALNELTEEHSKAT--QQWVEKQAHLEKEL 366
Cdd:TIGR00618  313 HTELQSK-------MRSRAKLLMKRAAHVKQQSSIEEQRR----LLQTLHSQEIHIRDAHEVATsiREISCQQHTLTQHI 381

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 861483604   367 STALQDKKCLEEKNEILQGKLSQLEERLAQLpESPRQEKGEVLGDVLQLESLKQEAATLAtnnTQLQARVEMLENEQGQK 446
Cdd:TIGR00618  382 HTLQQQKTTLTQKLQSLCKELDILQREQATI-DTRTSAFRDLQGQLAHAKKQQELQQRYA---ELCAAAITCTAQCEKLE 457

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 861483604   447 EAQLLGERSHFEEEKQQLASLitnlqssiSNLSQAKEELEQASQAQGAKLNAQVASLTAELTTLSATLQQqdqelAGLKQ 526
Cdd:TIGR00618  458 KIHLQESAQSLKEREQQLQTK--------EQIHLQETRKKAVVLARLLELQEEPCPLCGSCIHPNPARQD-----IDNPG 524

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 861483604   527 QAQKKQAQLAQSLQQQEQASQGLRHQVEqlsgSLKQKEKQLEEAARELDASRRDHAQQLATAAKAQETSLRERDAACQQL 606
Cdd:TIGR00618  525 PLTRRMQRGEQTYAQLETSEEDVYHQLT----SERKQRASLKEQMQEIQQSFSILTQCDNRSKEDIPNLQNITVRLQDLT 600

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 861483604   607 EALEKEKAAKLEILQQQLQAANEAQDSAQNSVTQAQREKAELSQKVEELHALIEAAHQEQCEAQTQVAALEARLKAE--- 683
Cdd:TIGR00618  601 EKLSEAEDMLACEQHALLRKLQPEQDLQDVRLHLQQCSQELALKLTALHALQLTLTQERVREHALSIRVLPKELLASrql 680

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 861483604   684 ---------QQKATEREKVAQEKAQLQEQLWSLEESLKITK---GSLEEEKCRAAAALEEHQHHISEMEAESRSLAEQHK 751
Cdd:TIGR00618  681 alqkmqsekEQLTYWKEMLAQCQTLLRELETHIEEYDREFNeieNASSSLGSDLAAREDALNQSLKELMHQARTVLKART 760

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 861483604   752 QERKELEEEKAKRRGLGVQLQQLA---ETHQAETKALRQELA--KARTSNNMAEREVELLVKEVKTWRKRYEDSQQGETQ 826
Cdd:TIGR00618  761 EAHFNNNEEVTAALQTGAELSHLAaeiQFFNRLREEDTHLLKtlEAEIGQEIPSDEDILNLQCETLVQEEEQFLSRLEEK 840

                          650       660       670
                   ....*....|....*....|....*....|.
gi 861483604   827 YGLQEQLTTLKEEYEKSCQELRETKEKMAGI 857
Cdd:TIGR00618  841 SATLGEITHQLLKYEECSKQLAQLTQEQAKI 871
COG3899 COG3899
Predicted ATPase [General function prediction only];
870-1442 1.35e-03

Predicted ATPase [General function prediction only];


Pssm-ID: 443106 [Multi-domain]  Cd Length: 1244  Bit Score: 44.08  E-value: 1.35e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 861483604  870 SELAQLHANLARALQQV--QEKENRAQKLAD--DLSTLQEKMAATSKEVARlEALVRKAGEQQE---TASLELLKEPPKT 942
Cdd:COG3899   663 EERRALHRRIARALEARgpEPLEERLFELAHhlNRAGERDRAARLLLRAAR-RALARGAYAEALrylERALELLPPDPEE 741

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 861483604  943 RDRESewVEEQQGQQLCSTQAALRAMEREAEQMGTELEKLRAALMESQGQQQEERGQQEREVARLTQERGQAEADLALEK 1022
Cdd:COG3899   742 EYRLA--LLLELAEALYLAGRFEEAEALLERALAARALAALAALRHGNPPASARAYANLGLLLLGDYEEAYEFGELALAL 819

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 861483604 1023 AAKAELEMRLQNALNeQQAEFANLQEALSRALSEKEGKDQELSKLCEQEAVQRMELKELLQTVEQLKAQLAKKEKEQQQS 1102
Cdd:COG3899   820 AERLGDRRLEARALF-NLGFILHWLGPLREALELLREALEAGLETGDAALALLALAAAAAAAAAAAALAAAAAAAARLLA 898

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 861483604 1103 ARGASGENASGMGTQSEAVGKMEALRAKVSKLEQQCQQQQEEADSLARSLESERAFHVERDRALETLQGQLEEKARELGY 1182
Cdd:COG3899   899 AAAAALAAAAAAAALAAAELARLAAAAAAAAALALAAAAAAAAAAALAAAAAAAALAAALALAAAAAAAAAAALAAAAAA 978

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 861483604 1183 SQAASASAQRELATLRAKAQDHSKAEEEWKAQVARGQQEAVRKGSLISSLEEEVSILNRQVLEKEGESKELKRLVIAESE 1262
Cdd:COG3899   979 AAAAAAAAAAAALEAAAAALLALLAAAAAAAAAAAALAAALLAAALAALAAAAAAAALLAAAAALALLAALAAAAAAAAA 1058

                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 861483604 1263 KSQKLEERLRLLQMETASNSARAAERSSALREEVQSLREEVEKQRAASENLRQELASQAERAEELGQELkAWQEKFFQKE 1342
Cdd:COG3899  1059 AAALAAAAALLAAAAAAAAAAAAAAAAAALAAALAAAALAAAAAAALALAAALAALALAAALAALALAA-AARAAAALLL 1137

                         490       500       510       520       530       540       550       560
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 861483604 1343 QALSALQLEHTSTQALVSELLPAKHLCQQLQAEQVAAEKRHREELEQSKQAAGGLRTELMRAQRELGELVPLRQKVAEQE 1422
Cdd:COG3899  1138 LAAALALALAALLLLAALLLALALLLLALAALALAAALAALAAALLAAAAAAAAAAALLAALLALAARLAALLALALLAL 1217

                         570       580
                  ....*....|....*....|
gi 861483604 1423 RAAQQLRAEKASYAEQLSML 1442
Cdd:COG3899  1218 EAAALLLLLLLAALALAAAL 1237
EnvC COG4942
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, ...
 1483-1712 1.55e-03

Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 443969 [Multi-domain]  Cd Length: 377  Bit Score: 43.21  E-value: 1.55e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 861483604 1483 AAVRGDAETRLAEMRQEVQSTTHELevmtAKYEGAKVKVLEERQRFQEERQKLTAQVEQLEVFQREQTKKVEELSKKLAD 1562
Cdd:COG4942    19 ADAAAEAEAELEQLQQEIAELEKEL----AALKKEEKALLKQLAALERRIAALARRIRALEQELAALEAELAELEKEIAE 94

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 861483604 1563 YDQASKVQQQKLK----AFQAQGGE-------SQQEAQRLQTQLNELQVQLSQKEQAAEHYKVQMEKAKthyDAKKQQNQ 1631
Cdd:COG4942    95 LRAELEAQKEELAellrALYRLGRQpplalllSPEDFLDAVRRLQYLKYLAPARREQAEELRADLAELA---ALRAELEA 171

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 861483604 1632 ELQEQLQGLEQLQKENKELRAEAERLGQELQQAGLKTKEAEQTCRHLTAQVRSLEAQVAHADQQLRELGKFQVASDALKS 1711
Cdd:COG4942   172 ERAELEALLAELEEERAALEALKAERQKLLARLEKELAELAAELAELQQEAEELEALIARLEAEAAAAAERTPAAGFAAL 251


                  .
gi 861483604 1712 R 1712
Cdd:COG4942   252 K 252
46 PHA02562
endonuclease subunit; Provisional
 686-919 1.56e-03

endonuclease subunit; Provisional


Pssm-ID: 222878 [Multi-domain]  Cd Length: 562  Bit Score: 43.46  E-value: 1.56e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 861483604  686 KATEREkVAQEKAQLQEQLWSLEESLKITKGSLEEEKCRAAAALEEHQhhisEMEAESRSLAEQHKQERKELEEEKAKrr 765
Cdd:PHA02562  173 KDKIRE-LNQQIQTLDMKIDHIQQQIKTYNKNIEEQRKKNGENIARKQ----NKYDELVEEAKTIKAEIEELTDELLN-- 245

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 861483604  766 glgvqLQQLAETHQAETKALRQELAKARTsnnmaerEVELLVKEVKTWRKRYE---DSQQGETQYGLQEQLTTLKEEYEK 842
Cdd:PHA02562  246 -----LVMDIEDPSAALNKLNTAAAKIKS-------KIEQFQKVIKMYEKGGVcptCTQQISEGPDRITKIKDKLKELQH 313

                         170       180       190       200       210       220       230
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 861483604  843 SCQELRETKEKMAGIEAhselQIGQHQSELAQLHANLARALQQVQEKENRAQKLADDLSTLQEKMAATSKEVARLEA 919
Cdd:PHA02562  314 SLEKLDTAIDELEEIMD----EFNEQSKKLLELKNKISTNKQSLITLVDKAKKVKAAIEELQAEFVDNAEELAKLQD 386
MukB COG3096
Chromosome condensin MukBEF, ATPase and DNA-binding subunit MukB [Cell cycle control, cell ...
 549-793 1.65e-03

Chromosome condensin MukBEF, ATPase and DNA-binding subunit MukB [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 442330 [Multi-domain]  Cd Length: 1470  Bit Score: 43.79  E-value: 1.65e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 861483604  549 LRHQVEQLSGSLKQKEKQLEEAARELD---ASRRDHAQQLATAAKAQETSLRERDAACQQLEALE---KEKAAKLEILQQ 622
Cdd:COG3096   862 LRQQLDQLKEQLQLLNKLLPQANLLADetlADRLEELREELDAAQEAQAFIQQHGKALAQLEPLVavlQSDPEQFEQLQA 941

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 861483604  623 QLQAANEAQdsaqnsvTQAQREKAELSQKVEELHAL-IEAAHQEQCEAQTQVAALEARL-KAEQQKATEREKVAQEKAQL 700
Cdd:COG3096   942 DYLQAKEQQ-------RRLKQQIFALSEVVQRRPHFsYEDAVGLLGENSDLNEKLRARLeQAEEARREAREQLRQAQAQY 1014

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 861483604  701 QE--QLWSLEESLKITKGSLEEEKCRAAAALEEHQHHISEMEAESR-----SLAEQHKQERKELEEEKAKRRGLGVQLQQ 773
Cdd:COG3096  1015 SQynQVLASLKSSRDAKQQTLQELEQELEELGVQADAEAEERARIRrdelhEELSQNRSRRSQLEKQLTRCEAEMDSLQK 1094

                         250       260
                  ....*....|....*....|..
gi 861483604  774 LAETHQAETKALRQEL--AKAR 793
Cdd:COG3096  1095 RLRKAERDYKQEREQVvqAKAG 1116
PRK10476 PRK10476
multidrug transporter subunit MdtN;
559-679 1.95e-03

multidrug transporter subunit MdtN;


Pssm-ID: 182488 [Multi-domain]  Cd Length: 346  Bit Score: 42.71  E-value: 1.95e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 861483604  559 SLKQKEKQLEEAARELDASRRDHAQQLATAAKAQETSLRER---DAACQQLEALEKeKAAKLEILQQQLQAANEAQDSAQ 635
Cdd:PRK10476   87 TVAQAQADLALADAQIMTTQRSVDAERSNAASANEQVERARanaKLATRTLERLEP-LLAKGYVSAQQVDQARTAQRDAE 165

                          90       100       110       120
                  ....*....|....*....|....*....|....*....|....
gi 861483604  636 NSVTQAQREKAELSQKVEELHALIEAAHQEqcEAQTQVAALEAR 679
Cdd:PRK10476  166 VSLNQALLQAQAAAAAVGGVDALVAQRAAR--EAALAIAELHLE 207
Surf_Exclu_PgrA TIGR04320
SEC10/PgrA surface exclusion domain; This model describes a conserved domain found in surface ...
 551-657 2.00e-03

SEC10/PgrA surface exclusion domain; This model describes a conserved domain found in surface proteins of a number of Firmutes. Many members have LPXTG C-terminal anchoring motifs and a substantial number have the KxYKxGKxW putative sorting signal at the N-terminus. The tetracycline resistance plasmid pCF10 in Enterococcus faecalis promotes conjugal plasmid transfer in response to sex pheromones, but PgrA/Sec10 encoded by that plasmid, a member of this family, specifically inhibits the ability of cells to receive homologous plasmids. The phenomenon is called surface exclusion.


Pssm-ID: 275124 [Multi-domain]  Cd Length: 356  Bit Score: 42.79  E-value: 2.00e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 861483604   551 HQVEQLSGSLKQKEKQLEEAARELDASRRDHAQQLATAAKAQETSlrerDAACQQLEALEKE----KAAKLEILQQQLQA 626
Cdd:TIGR04320  247 TPIPNPPNSLAALQAKLATAQADLAAAQTALNTAQAALTSAQTAY----AAAQAALATAQKElanaQAQALQTAQNNLAT 322

                           90       100       110
                   ....*....|....*....|....*....|.
gi 861483604   627 ANEAQDSAQNSVTQAQREKAELSQKVEELHA 657
Cdd:TIGR04320  323 AQAALANAEARLAKAKEALANLNADLAKKQA 353
MARTX_Nterm NF012221
MARTX multifunctional-autoprocessing repeats-in-toxin holotoxin N-terminal region; This model ...
 1370-1723 2.02e-03

MARTX multifunctional-autoprocessing repeats-in-toxin holotoxin N-terminal region; This model describes the N-terminal 1900 amino acids of MARTX family multifunctional-autoprocessing repeats-in-toxin holotoxins, which contain both repeat regions that facilitate their entry into eukaryotic target cells, and multiple effector domains.


Pssm-ID: 467957 [Multi-domain]  Cd Length: 1848  Bit Score: 43.67  E-value: 2.02e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 861483604 1370 QQLQAEQVAAEKRHREELEQSKQAAG-GLRTELMRAQRELGELVPLRQKVAEQERAAQQLRAEKASYAEQLSMLKKahgl 1448
Cdd:NF012221 1501 QQKTLKLTAKAGSNRLEFKGTGHNDGlGYILDNVVATSESSQQADAVSKHAKQDDAAQNALADKERAEADRQRLEQ---- 1576

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 861483604 1449 laEENRGLGERAnlGRQF-LEVELDQAREKYIQ-ELAAVRGDAEtrlaEMRQEVQSTTHELEVMTAKYEGAKVKVLEERQ 1526
Cdd:NF012221 1577 --EKQQQLAAIS--GSQSqLESTDQNALETNGQaQRDAILEESR----AVTKELTTLAQGLDALDSQATYAGESGDQWRN 1648

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 861483604 1527 RFQEeRQKLTAQvEQLEVFQREQTKKVEELSKKLADYDQASKVQQQKLKAFQAQGGESQQEAQrLQTQLNELQVQLSQKE 1606
Cdd:NF012221 1649 PFAG-GLLDRVQ-EQLDDAKKISGKQLADAKQRHVDNQQKVKDAVAKSEAGVAQGEQNQANAE-QDIDDAKADAEKRKDD 1725

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 861483604 1607 QAAEHYKVQMEKAKTHYDAKKQQNQELQeqlqglEQLQKENKELRAEAErlgqelqQAGLKTKEAEQTCRH------LTA 1680
Cdd:NF012221 1726 ALAKQNEAQQAESDANAAANDAQSRGEQ------DASAAENKANQAQAD-------AKGAKQDESDKPNRQgaagsgLSG 1792

                         330       340       350       360
                  ....*....|....*....|....*....|....*....|...
gi 861483604 1681 QVRSLEAqVAHADQQLRElgKFQVASDALKSREPQAKPQLDLS 1723
Cdd:NF012221 1793 KAYSVEG-VAEPGSHINP--DSPAAADGRFSEGLTEQEQEALE 1832
Macoilin pfam09726
Macoilin family; The Macoilin proteins has an N-terminal portion that is composed of 5 ...
 557-859 2.07e-03

Macoilin family; The Macoilin proteins has an N-terminal portion that is composed of 5 trasnmembrane helices, followed by a C-terminal coiled-coil region. Macoilin is a highly conserved protein present in eukaryotes. Macoilin appears to be found in the ER and be involved in the function of neurons.


Pssm-ID: 462859 [Multi-domain]  Cd Length: 670  Bit Score: 43.30  E-value: 2.07e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 861483604   557 SGSLKQKEKQLEEAARELDASRRDHAQQLATAAKAQETSLRERDAACQQLEA-LEKEKAAKLEiLQQQLQAANEAQDSAQ 635
Cdd:pfam09726  358 SSSSKNSKKQKGPGGKSGARHKDPAENCIPNNQLSKPDALVRLEQDIKKLKAeLQASRQTEQE-LRSQISSLTSLERSLK 436

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 861483604   636 NSVTQAQREKAELSQKveeLHALIEAAHQEQceaQTqVAALEARLKAEQQKATEREKvaqekaQLQEqlwslEESLKitk 715
Cdd:pfam09726  437 SELGQLRQENDLLQTK---LHNAVSAKQKDK---QT-VQQLEKRLKAEQEARASAEK------QLAE-----EKKRK--- 495

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 861483604   716 gSLEEEKCRAAAALEEhqhhisemeAESRSLAEQHKQERKELEEEKAKrrgLGVQLqQLAETHQAETKALRQELAKARTS 795
Cdd:pfam09726  496 -KEEEATAARAVALAA---------ASRGECTESLKQRKRELESEIKK---LTHDI-KLKEEQIRELEIKVQELRKYKES 561

                          250       260       270       280       290       300       310
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 861483604   796 nnmaEREVELLVKEVKTWRKR---YEDSQQGETQYGL---------QEQLTTLKEEYEKSCQELRETKEKMAGIEA 859
Cdd:pfam09726  562 ----EKDTEVLMSALSAMQDKnqhLENSLSAETRIKLdlfsalgdaKRQLEIAQGQIYQKDQEIKDLKQKIAEVMA 633
GumC COG3206
Exopolysaccharide export protein/domain GumC/Wzc1 [Cell wall/membrane/envelope biogenesis];
582-835 2.19e-03

Exopolysaccharide export protein/domain GumC/Wzc1 [Cell wall/membrane/envelope biogenesis];


Pssm-ID: 442439 [Multi-domain]  Cd Length: 687  Bit Score: 43.08  E-value: 2.19e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 861483604  582 AQQLATAAKAQETSLRERDAAcQQLEALEKEkaakLEILQQQLQAANEAQDS--AQNSVTQAQREKAELSQKVEELHALI 659
Cdd:COG3206   154 ANALAEAYLEQNLELRREEAR-KALEFLEEQ----LPELRKELEEAEAALEEfrQKNGLVDLSEEAKLLLQQLSELESQL 228

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 861483604  660 EAAHQEQCEAQTQVAALEARLKAEQQKATEREKvAQEKAQLQEQLWSLEeslkitkgsleeekcraaaaleehqhhiSEM 739
Cdd:COG3206   229 AEARAELAEAEARLAALRAQLGSGPDALPELLQ-SPVIQQLRAQLAELE----------------------------AEL 279

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 861483604  740 EAESRSLAEQH------KQERKELEEEKAKR-RGLGVQLQQLAETHQAETKALRQELAKART-SNNMAEREVEL--LVKE 809
Cdd:COG3206   280 AELSARYTPNHpdvialRAQIAALRAQLQQEaQRILASLEAELEALQAREASLQAQLAQLEArLAELPELEAELrrLERE 359

                         250       260
                  ....*....|....*....|....*.
gi 861483604  810 VKTWRKRYEDSQQGETQYGLQEQLTT 835
Cdd:COG3206   360 VEVARELYESLLQRLEEARLAEALTV 385
SMC_N pfam02463
RecF/RecN/SMC N terminal domain; This domain is found at the N terminus of SMC proteins. The ...
 1052-1735 2.23e-03

RecF/RecN/SMC N terminal domain; This domain is found at the N terminus of SMC proteins. The SMC (structural maintenance of chromosomes) superfamily proteins have ATP-binding domains at the N- and C-termini, and two extended coiled-coil domains separated by a hinge in the middle. The eukaryotic SMC proteins form two kind of heterodimers: the SMC1/SMC3 and the SMC2/SMC4 types. These heterodimers constitute an essential part of higher order complexes, which are involved in chromatin and DNA dynamics. This family also includes the RecF and RecN proteins that are involved in DNA metabolism and recombination.


Pssm-ID: 426784 [Multi-domain]  Cd Length: 1161  Bit Score: 43.42  E-value: 2.23e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 861483604  1052 RALSEKEGKDQELSKLCEQEAVQRMELKELLQTVEQLKAQLAKKEKEQQQSARGASGENASGMGTQSEAVGKMEALRAKV 1131
Cdd:pfam02463  174 ALKKLIEETENLAELIIDLEELKLQELKLKEQAKKALEYYQLKEKLELEEEYLLYLDYLKLNEERIDLLQELLRDEQEEI 253

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 861483604  1132 SKLEQQCQQQQEEADSLARSLESERAFHVERDRALETLQGQLEEKARELGYSQAASASAQRELATLRAKAQDHSKAEEEW 1211
Cdd:pfam02463  254 ESSKQEIEKEEEKLAQVLKENKEEEKEKKLQEEELKLLAKEEEELKSELLKLERRKVDDEEKLKESEKEKKKAEKELKKE 333

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 861483604  1212 KAQVARGQQEAVRKGSLISSLEEEVSILNRQVLEKEGESKELKRLVIAESEKSQKlEERLRLLQMETASNSARAAERSSA 1291
Cdd:pfam02463  334 KEEIEELEKELKELEIKREAEEEEEEELEKLQEKLEQLEEELLAKKKLESERLSS-AAKLKEEELELKSEEEKEAQLLLE 412

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 861483604  1292 LREEVQSLREEVEKQRAASENLRQELA-SQAERAEELGQELKAWQEKFFQKEQALSALQLEHTSTQALVSELLPAKHLCQ 1370
Cdd:pfam02463  413 LARQLEDLLKEEKKEELEILEEEEESIeLKQGKLTEEKEELEKQELKLLKDELELKKSEDLLKETQLVKLQEQLELLLSR 492

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 861483604  1371 QLQAEQVAAEKRHREELE----QSKQAAGGLRTELMRAQRELGELVPLRQKVAEQERAAQQLRAEKASYAEQ---LSMLK 1443
Cdd:pfam02463  493 QKLEERSQKESKARSGLKvllaLIKDGVGGRIISAHGRLGDLGVAVENYKVAISTAVIVEVSATADEVEERQklvRALTE 572

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 861483604  1444 KAHGLLAEENRGLGERANLGRQFLEVELDQAREKYIQELAAVRGDAETRLAEMRQEVQSTTHELEVMTAKYEGAKVKVLE 1523
Cdd:pfam02463  573 LPLGARKLRLLIPKLKLPLKSIAVLEIDPILNLAQLDKATLEADEDDKRAKVVEGILKDTELTKLKESAKAKESGLRKGV 652

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 861483604  1524 ERQRFQEERQKLTAQVEQLevfQREQTKKVEELSKKLADYDQASKVQQQKLKAFQAQGGESQQEAQRLQTQLNELQVQLS 1603
Cdd:pfam02463  653 SLEEGLAEKSEVKASLSEL---TKELLEIQELQEKAESELAKEEILRRQLEIKKKEQREKEELKKLKLEAEELLADRVQE 729

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 861483604  1604 QKEQAAEHYKVQMEKAKTHYDAKKQQNQELQEQLQGLEQLQKENKELRAEAERLGQELQQAGLKTKEAEQtcrhlTAQVR 1683
Cdd:pfam02463  730 AQDKINEELKLLKQKIDEEEEEEEKSRLKKEEKEEEKSELSLKEKELAEEREKTEKLKVEEEKEEKLKAQ-----EEELR 804

                          650       660       670       680       690
                   ....*....|....*....|....*....|....*....|....*....|..
gi 861483604  1684 SLEAQVAHADQQLRELGKFQVASDALKSREPQAKPQLDLSIDSLDLSCEEGT 1735
Cdd:pfam02463  805 ALEEELKEEAELLEEEQLLIEQEEKIKEEELEELALELKEEQKLEKLAEEEL 856
CusB_dom_1 pfam00529
Cation efflux system protein CusB domain 1; The cation efflux system protein CusB from E. coli ...
 620-765 2.24e-03

Cation efflux system protein CusB domain 1; The cation efflux system protein CusB from E. coli can be divided into four different domains, the first three domains of the protein are mostly beta-strands and the fourth forms an all alpha-helical domain. This entry represents the first beta-domain (domain 1) of CusB and it is formed by the N and C-terminal ends of the polypeptide (residues 89-102 and 324-385). CusB is part of the copper-transporting efflux system CusCFBA. This domain can also be found in other membrane-fusion proteins, such as HlyD, MdtN, MdtE and AaeA. HlyD is a component of the prototypical alpha-haemolysin (HlyA) bacterial type I secretion system, along with the other components HlyB and TolC. HlyD is anchored in the cytoplasmic membrane by a single transmembrane domain and has a large periplasmic domain within the carboxy-terminal 100 amino acids, HlyB and HlyD form a stable complex that binds the recombinant protein bearing a C-terminal HlyA signal sequence and ATP in the cytoplasm. HlyD, HlyB and TolC combine to form the three-component ABC transporter complex that forms a trans-membrane channel or pore through which HlyA can be transferred directly to the extracellular medium. Cutinase has been shown to be transported effectively through this pore.


Pssm-ID: 425733 [Multi-domain]  Cd Length: 322  Bit Score: 42.41  E-value: 2.24e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 861483604   620 LQQQLQAANEAQDSAQNSVTQAQREKAELSQKVEELHAL---IEAAHQEQCEAQTQVAALEARLKAEQQKATEREKVAQE 696
Cdd:pfam00529   56 YQAALDSAEAQLAKAQAQVARLQAELDRLQALESELAISrqdYDGATAQLRAAQAAVKAAQAQLAQAQIDLARRRVLAPI 135

                           90       100       110       120       130       140
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 861483604   697 KAQLQEQLWSLEESLKITKGSLEEEKCRAAAALEEHQHHISEMEAESRSLAEQHKQERKELEEEKAKRR 765
Cdd:pfam00529  136 GGISRESLVTAGALVAQAQANLLATVAQLDQIYVQITQSAAENQAEVRSELSGAQLQIAEAEAELKLAK 204
COG4913 COG4913
Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];
220-397 2.28e-03

Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];


Pssm-ID: 443941 [Multi-domain]  Cd Length: 1089  Bit Score: 43.37  E-value: 2.28e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 861483604  220 KKQLADERNNRDELELELAEHRKLLTEKDAQISMMQQRIDRLALLNEKQAA----SPLEpRELEELRGKNESLT---FRL 292
Cdd:COG4913   609 RAKLAALEAELAELEEELAEAEERLEALEAELDALQERREALQRLAEYSWDeidvASAE-REIAELEAELERLDassDDL 687

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 861483604  293 HETLKQCQDLKTEKGQMDRKINQLSEENGDLSFKLREFASNLQQLQGALNELTEEHSKATQQWVEKQAHLEKELSTALQD 372
Cdd:COG4913   688 AALEEQLEELEAELEELEEELDELKGEIGRLEKELEQAEEELDELQDRLEAAEDLARLELRALLEERFAAALGDAVEREL 767

                         170       180
                  ....*....|....*....|....*
gi 861483604  373 KKCLEEKNEILQGKLSQLEERLAQL 397
Cdd:COG4913   768 RENLEERIDALRARLNRAEEELERA 792
DR0291 COG1579
Predicted nucleic acid-binding protein DR0291, contains C4-type Zn-ribbon domain [General ...
 612-763 2.49e-03

Predicted nucleic acid-binding protein DR0291, contains C4-type Zn-ribbon domain [General function prediction only];


Pssm-ID: 441187 [Multi-domain]  Cd Length: 236  Bit Score: 41.83  E-value: 2.49e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 861483604  612 EKAAKLEILQQ---QLQAANEAQDSAQNSVTQAQREKAELSQKVEELHALIEAAHQEQCEAQTQVAALEARLKAEQQKAT 688
Cdd:COG1579     4 EDLRALLDLQEldsELDRLEHRLKELPAELAELEDELAALEARLEAAKTELEDLEKEIKRLELEIEEVEARIKKYEEQLG 83

                          90       100       110       120       130       140       150
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 861483604  689 EREKVAQEKAQLQEqlwslEESLKITKGSLEEEKCRAAAALEEHQHHISEMEAESRSLAEQHKQERKELEEEKAK 763
Cdd:COG1579    84 NVRNNKEYEALQKE-----IESLKRRISDLEDEILELMERIEELEEELAELEAELAELEAELEEKKAELDEELAE 153
PRK09039 PRK09039
peptidoglycan -binding protein;
1018-1100 2.53e-03

peptidoglycan -binding protein;


Pssm-ID: 181619 [Multi-domain]  Cd Length: 343  Bit Score: 42.26  E-value: 2.53e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 861483604 1018 LALEKAAKAELEMR---LQNALNEQQAEFANLQEA---LSRALSEKEGKDQELSK-LCEQEAV---QRMELKELLQTVEQ 1087
Cdd:PRK09039   69 LSLERQGNQDLQDSvanLRASLSAAEAERSRLQALlaeLAGAGAAAEGRAGELAQeLDSEKQVsarALAQVELLNQQIAA 148

                          90       100
                  ....*....|....*....|...
gi 861483604 1088 LKAQLA----------KKEKEQQ 1100
Cdd:PRK09039  149 LRRQLAaleaaldaseKRDRESQ 171
YhaN COG4717
Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown];
871-1317 2.84e-03

Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown];


Pssm-ID: 443752 [Multi-domain]  Cd Length: 641  Bit Score: 42.83  E-value: 2.84e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 861483604  871 ELAQLHANLARALQQVQEKENRAQKLADDLSTLQEKMAATSKEVARLEALVRKAGEQQETASLELLKEPPKTRDRESEWV 950
Cdd:COG4717    75 ELEEELKEAEEKEEEYAELQEELEELEEELEELEAELEELREELEKLEKLLQLLPLYQELEALEAELAELPERLEELEER 154

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 861483604  951 EEQQGQQLCSTQAALRAMEREAEQMGTELEKLRAALMESQGQQQEERGQQEREVARLTQERGQAEADLALEKAAKAELEM 1030
Cdd:COG4717   155 LEELRELEEELEELEAELAELQEELEELLEQLSLATEEELQDLAEELEELQQRLAELEEELEEAQEELEELEEELEQLEN 234

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 861483604 1031 RLQNALNEQQAEFANLQEALSRALSEKEGKDQELSKLCEQEAVQRMELKELLQTVEQLKAQLAKKEKEQQQSARGASGEN 1110
Cdd:COG4717   235 ELEAAALEERLKEARLLLLIAAALLALLGLGGSLLSLILTIAGVLFLVLGLLALLFLLLAREKASLGKEAEELQALPALE 314

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 861483604 1111 AsgmgtqseavGKMEALRAKVSKLEQQCQQQQEEADSLARSLESERAFHVERDRALETLQGQLEEKARELGYSQAASASa 1190
Cdd:COG4717   315 E----------LEEEELEELLAALGLPPDLSPEELLELLDRIEELQELLREAEELEEELQLEELEQEIAALLAEAGVED- 383

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 861483604 1191 qreLATLRAKAQDHSKAEE-EWKAQVARGQQEAVRKGSLISSLEEEVSILNRQVLEKEGESKELKRLVIAESEKSQKLEE 1269
Cdd:COG4717   384 ---EEELRAALEQAEEYQElKEELEELEEQLEELLGELEELLEALDEEELEEELEELEEELEELEEELEELREELAELEA 460

                         410       420       430       440
                  ....*....|....*....|....*....|....*....|....*...
gi 861483604 1270 RLRllQMETASNSARAAERSSALREEVQSLREEVEKQRAASENLRQEL 1317
Cdd:COG4717   461 ELE--QLEEDGELAELLQELEELKAELRELAEEWAALKLALELLEEAR 506
alph_xenorhab_A NF033928
alpha-xenorhabdolysin family binary toxin subunit A; Alpha-xenorhabdolysin was the founding ...
 266-522 2.86e-03

alpha-xenorhabdolysin family binary toxin subunit A; Alpha-xenorhabdolysin was the founding member of a family of alpha-helical pore-forming binary toxins. YaxAB from Yersinia enterocolitica has been studied structurally. This HMM represents subunit A proteins such as XaxA and YaxA, capable of binding to the membrane even in the absence of the B subunit. This family is related to the Bacillus haemolytic enterotoxin family (see PF05791.9), although thresholds for this HMM are set to exclude that family.


Pssm-ID: 468250 [Multi-domain]  Cd Length: 340  Bit Score: 42.29  E-value: 2.86e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 861483604  266 EKQAASPLEPRELEELRG--KNESLTFRLHE--TLKQCQDLKTEKGQMDRKINQLSEENGDLSFKLREFASNLQ------ 335
Cdd:NF033928   35 PKDGIPGLEPKDLLDLFQniRNHARSWSNLEpkIKQLANDLANYARNIVVTGNPIIDLINEMPIIKRGDLTEEElselpp 114

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 861483604  336 ------------QLQGALNEL---TEEHSKATQQWVEK----QAHLEKELSTALQDKKCLEEKN------EILQGKLSQL 390
Cdd:NF033928  115 iplssddkeivkELKEILEDLkndIKDYQQKADDVKKElddfENDLREELLPQLKLKKKLYDDNlgsdsiEELREKIDQL 194

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 861483604  391 EERLAQLPESPRQEKGEVLGDVLQL----------ESLKQEAAtlatnntqlQARVEMLENEQGQKEAQLlgershfeEE 460
Cdd:NF033928  195 EKEIEQLNKEYDDYVKLSFTGLAGGpiglaitggiFGSKAEKI---------RKEKNALIQEIDELQEQL--------KK 257

                         250       260       270       280       290       300
                  ....*....|....*....|....*....|....*....|....*....|....*....|..
gi 861483604  461 KQQLASLITNLQSSISNLSQAKEELEQASQaqgaKLNAQVASLTAELTTLSATLQQQDQELA 522
Cdd:NF033928  258 KNALLGSLERLQTSLDDILTRMEDALPALK----KLKGVWQSLLTDIDSSINALKEIDDADS 315
EnvC COG4942
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, ...
 897-1147 2.96e-03

Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 443969 [Multi-domain]  Cd Length: 377  Bit Score: 42.44  E-value: 2.96e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 861483604  897 ADDLSTLQEKMAATSKEVARLEALVRKAGEQQETASLELlkeppktrdresewveEQQGQQLCSTQAALRAMEREAEQMG 976
Cdd:COG4942    19 ADAAAEAEAELEQLQQEIAELEKELAALKKEEKALLKQL----------------AALERRIAALARRIRALEQELAALE 82

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 861483604  977 TELEKLRAALMESQGQQQEERGQQEREVARLTQERGQAEADLALEKAAKAELEMRLQNalneqqaeFANLQEALSRALSE 1056
Cdd:COG4942    83 AELAELEKEIAELRAELEAQKEELAELLRALYRLGRQPPLALLLSPEDFLDAVRRLQY--------LKYLAPARREQAEE 154

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 861483604 1057 KEGKDQELSKLCEQEAVQRMELKELLQTVEQLKAQLAKKEKEQQQSARGASGENASGMGTQSEAVGKMEALRAKVSKLEQ 1136
Cdd:COG4942   155 LRADLAELAALRAELEAERAELEALLAELEEERAALEALKAERQKLLARLEKELAELAAELAELQQEAEELEALIARLEA 234

                         250
                  ....*....|.
gi 861483604 1137 QCQQQQEEADS 1147
Cdd:COG4942   235 EAAAAAERTPA 245
Cast pfam10174
RIM-binding protein of the cytomatrix active zone; This is a family of proteins that form part ...
 209-858 2.99e-03

RIM-binding protein of the cytomatrix active zone; This is a family of proteins that form part of the CAZ (cytomatrix at the active zone) complex which is involved in determining the site of synaptic vesicle fusion. The C-terminus is a PDZ-binding motif that binds directly to RIM (a small G protein Rab-3A effector). The family also contains four coiled-coil domains.


Pssm-ID: 431111 [Multi-domain]  Cd Length: 766  Bit Score: 42.89  E-value: 2.99e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 861483604   209 LQTPQFQMRRLKKQLADERNNRDELELELAEHRKLLTEKDAQISMMQQRIDRLALLNEKQAasplepRELEELRGKNESL 288
Cdd:pfam10174   69 NQHLQLTIQALQDELRAQRDLNQLLQQDFTTSPVDGEDKFSTPELTEENFRRLQSEHERQA------KELFLLRKTLEEM 142

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 861483604   289 TFRLhETLKQ--------CQDLkTEKGQMDRKINQLSEENGDLSFKLREFASNLQQLQGALNELTEEHSKatqqwVEKQA 360
Cdd:pfam10174  143 ELRI-ETQKQtlgardesIKKL-LEMLQSKGLPKKSGEEDWERTRRIAEAEMQLGHLEVLLDQKEKENIH-----LREEL 215

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 861483604   361 HLEKELSTALQDKKCLEEKNEILQGKLSQLEERLAQLPESPRQEKGEVLGDVLQLESLKQEAATLATNNTQLQARVEMLE 440
Cdd:pfam10174  216 HRRNQLQPDPAKTKALQTVIEMKDTKISSLERNIRDLEDEVQMLKTNGLLHTEDREEEIKQMEVYKSHSKFMKNKIDQLK 295

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 861483604   441 NEQGQKEAQLLGERSHFEEekqqlaslITNLQSSISNLSQAKEELEQASQAQGAKLNAQVASLTAELTTLSATL---QQQ 517
Cdd:pfam10174  296 QELSKKESELLALQTKLET--------LTNQNSDCKQHIEVLKESLTAKEQRAAILQTEVDALRLRLEEKESFLnkkTKQ 367

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 861483604   518 DQELAGLKQQAQKKQAQLAQSLQQQEQASQGLRHQVEQLSGSLKQKEKQLEEAAR-----ELDASRRDHAqqLATAAKAQ 592
Cdd:pfam10174  368 LQDLTEEKSTLAGEIRDLKDMLDVKERKINVLQKKIENLQEQLRDKDKQLAGLKErvkslQTDSSNTDTA--LTTLEEAL 445

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 861483604   593 ETSLRERDAACQQLEALEKEKAAKLEILQQQLQAANEAQDSAQNSVTQAQREKAELSQKVEEL--HALIEAAHQEQCEAQ 670
Cdd:pfam10174  446 SEKERIIERLKEQREREDRERLEELESLKKENKDLKEKVSALQPELTEKESSLIDLKEHASSLasSGLKKDSKLKSLEIA 525

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 861483604   671 TQVAALEA-RLKAEQQKATEREKVAQEKAQLQEQLWSLEESLKITKgsleEEKCRAAAALEEHQHHISEMEAEsrslaeQ 749
Cdd:pfam10174  526 VEQKKEECsKLENQLKKAHNAEEAVRTNPEINDRIRLLEQEVARYK----EESGKAQAEVERLLGILREVENE------K 595

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 861483604   750 HKQERKELEEEKAKRRGLGVQlqqlaETHQAETKALRQElakartsnnMAEREVELLVKEVKTWRKRYEDSQQgetqygl 829
Cdd:pfam10174  596 NDKDKKIAELESLTLRQMKEQ-----NKKVANIKHGQQE---------MKKKGAQLLEEARRREDNLADNSQQ------- 654

                          650       660
                   ....*....|....*....|....*....
gi 861483604   830 qEQLTTLKEEYEKSCQELRETKEKMAGIE 858
Cdd:pfam10174  655 -LQLEELMGALEKTRQELDATKARLSSTQ 682
YhaN COG4717
Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown];
1368-1743 3.23e-03

Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown];


Pssm-ID: 443752 [Multi-domain]  Cd Length: 641  Bit Score: 42.45  E-value: 3.23e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 861483604 1368 LCQQLQAEQVAAEKRHREELEQSKQAAGGLRTELMRAQRELGELVPLRQKVAEQERAAQQLRAEKASYAEQLSMLKKAHG 1447
Cdd:COG4717    47 LLERLEKEADELFKPQGRKPELNLKELKELEEELKEAEEKEEEYAELQEELEELEEELEELEAELEELREELEKLEKLLQ 126

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 861483604 1448 LLAEENRGLGERANLGRqfLEVELDQAREKyIQELAAVRGDAETRLAEMRQEVQSTTHELEVMTAKYEGAKVKVLEERQR 1527
Cdd:COG4717   127 LLPLYQELEALEAELAE--LPERLEELEER-LEELRELEEELEELEAELAELQEELEELLEQLSLATEEELQDLAEELEE 203

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 861483604 1528 FQEERQKLTAQVEQLEVFQREQTKKVEELSKKLADYDQASKVQQQKL--------------------------KAFQAQG 1581
Cdd:COG4717   204 LQQRLAELEEELEEAQEELEELEEELEQLENELEAAALEERLKEARLllliaaallallglggsllsliltiaGVLFLVL 283

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 861483604 1582 GESQQEAQRLQTQLNELQVQLSQKEQAAEHYKVQMEKAKTHYDAKKQQNQELQEQLQGLEQLQKENKELRAEAERLGQEL 1661
Cdd:COG4717   284 GLLALLFLLLAREKASLGKEAEELQALPALEELEEEELEELLAALGLPPDLSPEELLELLDRIEELQELLREAEELEEEL 363

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 861483604 1662 QQAGLKTKEAEqtcrhltaqvrSLEAQVAHADQQLRELGKFQVASDALKSREPQAKPQLDLSIDSLDLSCEEGTPLSITS 1741
Cdd:COG4717   364 QLEELEQEIAA-----------LLAEAGVEDEEELRAALEQAEEYQELKEELEELEEQLEELLGELEELLEALDEEELEE 432


                  ..
gi 861483604 1742 KL 1743
Cdd:COG4717   433 EL 434
rad50 TIGR00606
rad50; All proteins in this family for which functions are known are involvedin recombination, ...
 207-928 3.60e-03

rad50; All proteins in this family for which functions are known are involvedin recombination, recombinational repair, and/or non-homologous end joining.They are components of an exonuclease complex with MRE11 homologs. This family is distantly related to the SbcC family of bacterial proteins.This family is based on the phylogenomic analysis of JA Eisen (1999, Ph.D. Thesis, Stanford University).


Pssm-ID: 129694 [Multi-domain]  Cd Length: 1311  Bit Score: 42.73  E-value: 3.60e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 861483604   207 DILQTPQF--QMRRLKKQLADERNNRDELELELaehRKLLTEKDAQISMMQQRIDRLALLNEKQAASPLEPRELEELRGK 284
Cdd:TIGR00606  177 EIFSATRYikALETLRQVRQTQGQKVQEHQMEL---KYLKQYKEKACEIRDQITSKEAQLESSREIVKSYENELDPLKNR 253

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 861483604   285 NEsltfRLHETLKQCQDLKTEKGQMDRKINQLSEENGDLSFKLREFasnLQQLQGALNELTEEHSKATQQWVEKQAHLEK 364
Cdd:TIGR00606  254 LK----EIEHNLSKIMKLDNEIKALKSRKKQMEKDNSELELKMEKV---FQGTDEQLNDLYHNHQRTVREKERELVDCQR 326

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 861483604   365 ELSTALQDKKCLEEKNEILQGKLSQLEERLAQLPESPRQEKGEVLGDVLQLESLKQEAAtlATNNTQLQARVEMLENEQg 444
Cdd:TIGR00606  327 ELEKLNKERRLLNQEKTELLVEQGRLQLQADRHQEHIRARDSLIQSLATRLELDGFERG--PFSERQIKNFHTLVIERQ- 403

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 861483604   445 qkeaqllgershfEEEKQQLASLITNLQSSISNLSQAKEELEQASQAQGAKLNAQVASLTAELTTLSATLQQQDQELAGL 524
Cdd:TIGR00606  404 -------------EDEAKTAAQLCADLQSKERLKQEQADEIRDEKKGLGRTIELKKEILEKKQEELKFVIKELQQLEGSS 470

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 861483604   525 KQQAQKKQAQLAQSLQQQEQASqglrhqvEQLSGSLKQKEKQLEEAARELDASRRDHAQQLATAAKAQETSlrerdaacQ 604
Cdd:TIGR00606  471 DRILELDQELRKAERELSKAEK-------NSLTETLKKEVKSLQNEKADLDRKLRKLDQEMEQLNHHTTTR--------T 535

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 861483604   605 QLEALEKEKAAKleilQQQLQAANEAQDSAQNSVTQAQREKAELSQKVEELHALIEAAHQEQCEAQTQVAALEarlKAEQ 684
Cdd:TIGR00606  536 QMEMLTKDKMDK----DEQIRKIKSRHSDELTSLLGYFPNKKQLEDWLHSKSKEINQTRDRLAKLNKELASLE---QNKN 608

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 861483604   685 QKATEREKVAQEKAQLQEQLWSL--EESLKITKGSLEEEKCRA-------AAALEEHQHHISEMEAESRS---LAEQHKQ 752
Cdd:TIGR00606  609 HINNELESKEEQLSSYEDKLFDVcgSQDEESDLERLKEEIEKSskqramlAGATAVYSQFITQLTDENQSccpVCQRVFQ 688

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 861483604   753 ERKELEEEKAKRRGLGVQLQQLAETHQAETKALRQELAKARTSNNMAEREVELLVKEVKTWRKRYE--DSQQGETQYGLQ 830
Cdd:TIGR00606  689 TEAELQEFISDLQSKLRLAPDKLKSTESELKKKEKRRDEMLGLAPGRQSIIDLKEKEIPELRNKLQkvNRDIQRLKNDIE 768

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 861483604   831 EQLTTL-----KEEYEKSCQELRETKEKMAGIEAHSELQIGQHQSEL--AQLHANLARALQQVQEKENRAQKLADDLSTL 903
Cdd:TIGR00606  769 EQETLLgtimpEEESAKVCLTDVTIMERFQMELKDVERKIAQQAAKLqgSDLDRTVQQVNQEKQEKQHELDTVVSKIELN 848

                          730       740
                   ....*....|....*....|....*
gi 861483604   904 QEKMAATSKEVARLEALVRKAGEQQ 928
Cdd:TIGR00606  849 RKLIQDQQEQIQHLKSKTNELKSEK 873
PRK11281 PRK11281
mechanosensitive channel MscK;
582-822 3.91e-03

mechanosensitive channel MscK;


Pssm-ID: 236892 [Multi-domain]  Cd Length: 1113  Bit Score: 42.59  E-value: 3.91e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 861483604  582 AQQLATAAKAQETSLRERDAACQQLEALEKEKAAKLE--ILQQQLQAAneaqdsaQNSVTQAQREKAELsqkvEELHALI 659
Cdd:PRK11281   21 CLSSAFARAASNGDLPTEADVQAQLDALNKQKLLEAEdkLVQQDLEQT-------LALLDKIDRQKEET----EQLKQQL 89

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 861483604  660 EAAHQEQCEAQTQVAALEARLKAEQQKATEREKVAQEKAQLQEQLWSLEE---------SLKITKGSLEEekcRAAAALE 730
Cdd:PRK11281   90 AQAPAKLRQAQAELEALKDDNDEETRETLSTLSLRQLESRLAQTLDQLQNaqndlaeynSQLVSLQTQPE---RAQAALY 166

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 861483604  731 EHQHHISE----------------------MEAESRSLAEQHKQERKELEEEkakrrglgVQLQQLAEthqaetkaLRQE 788
Cdd:PRK11281  167 ANSQRLQQirnllkggkvggkalrpsqrvlLQAEQALLNAQNDLQRKSLEGN--------TQLQDLLQ--------KQRD 230

                         250       260       270
                  ....*....|....*....|....*....|....
gi 861483604  789 LAKARTsnNMAEREVELLVKEVKtwRKRYEDSQQ 822
Cdd:PRK11281  231 YLTARI--QRLEHQLQLLQEAIN--SKRLTLSEK 260
PRK12705 PRK12705
hypothetical protein; Provisional
 620-764 4.20e-03

hypothetical protein; Provisional


Pssm-ID: 237178 [Multi-domain]  Cd Length: 508  Bit Score: 42.00  E-value: 4.20e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 861483604  620 LQQQLQAANEAQDSAQNSVTQAQREKAELSQKVEELhaLIEAAHQEQCEAQTQVAALEARLKAEQQKATEREKVAQEKAQ 699
Cdd:PRK12705   25 LKKRQRLAKEAERILQEAQKEAEEKLEAALLEAKEL--LLRERNQQRQEARREREELQREEERLVQKEEQLDARAEKLDN 102

                          90       100       110       120       130       140
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 861483604  700 LQEQLWSLEESLKITKGSLEEEKCRAAAALEEhqhhISEMEAESrSLAEQHKQERKELEEEKAKR 764
Cdd:PRK12705  103 LENQLEEREKALSARELELEELEKQLDNELYR----VAGLTPEQ-ARKLLLKLLDAELEEEKAQR 162
hsdR PRK11448
type I restriction enzyme EcoKI subunit R; Provisional
 1293-1394 4.21e-03

type I restriction enzyme EcoKI subunit R; Provisional


Pssm-ID: 236912 [Multi-domain]  Cd Length: 1123  Bit Score: 42.25  E-value: 4.21e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 861483604 1293 REEVQSLREEVEKQRAASENLRQELASQAERAEELGQELKAWQEKFFQKEQALSALQLEHtstqalvsellpakhlcQQL 1372
Cdd:PRK11448  141 ENLLHALQQEVLTLKQQLELQAREKAQSQALAEAQQQELVALEGLAAELEEKQQELEAQL-----------------EQL 203

                          90       100
                  ....*....|....*....|...
gi 861483604 1373 QAEQVAAEKRHREEL-EQSKQAA 1394
Cdd:PRK11448  204 QEKAAETSQERKQKRkEITDQAA 226
mukB PRK04863
chromosome partition protein MukB;
1366-1727 4.33e-03

chromosome partition protein MukB;


Pssm-ID: 235316 [Multi-domain]  Cd Length: 1486  Bit Score: 42.25  E-value: 4.33e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 861483604 1366 KHLCQQLQAEQVAAEKRHREELEQSKQAAGGLRTELMRAQRELGE----LVPLRQKVAEQERAAQQLRAEKASYAEQLSM 1441
Cdd:PRK04863  260 KHLITESTNYVAADYMRHANERRVHLEEALELRRELYTSRRQLAAeqyrLVEMARELAELNEAESDLEQDYQAASDHLNL 339

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 861483604 1442 ----------LKKAHGLL------AEENRGLGERANLGRQFLEVELDQArEKYIQELAAVRGD-------AETRLAEMRQ 1498
Cdd:PRK04863  340 vqtalrqqekIERYQADLeeleerLEEQNEVVEEADEQQEENEARAEAA-EEEVDELKSQLADyqqaldvQQTRAIQYQQ 418

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 861483604 1499 EVQ---STTHELEVMTAKYEGAKVKVLEERQRFQEERQKLTAQVEQLEVFQ--REQTKKVEELSKKLAD---YDQASKVQ 1570
Cdd:PRK04863  419 AVQaleRAKQLCGLPDLTADNAEDWLEEFQAKEQEATEELLSLEQKLSVAQaaHSQFEQAYQLVRKIAGevsRSEAWDVA 498

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 861483604 1571 QQKLKAFQAQGGESQQEAQrLQTQLNELQvQLSQKEQAAEHYKVQMEK-AKTHYDAKKQQNQELQEQLQGLEQLQKENKE 1649
Cdd:PRK04863  499 RELLRRLREQRHLAEQLQQ-LRMRLSELE-QRLRQQQRAERLLAEFCKrLGKNLDDEDELEQLQEELEARLESLSESVSE 576

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 861483604 1650 LRAEAERLGQELQQAGLKTKEAEQTCRH-LTAQ--VRSLEAQVAHAD-----------QQLRELGKFQVASDALKSRepq 1715
Cdd:PRK04863  577 ARERRMALRQQLEQLQARIQRLAARAPAwLAAQdaLARLREQSGEEFedsqdvteymqQLLERERELTVERDELAAR--- 653

                         410
                  ....*....|..
gi 861483604 1716 aKPQLDLSIDSL 1727
Cdd:PRK04863  654 -KQALDEEIERL 664
COG4995 COG4995
Uncharacterized conserved protein, contains CHAT domain [Function unknown];
503-951 4.34e-03

Uncharacterized conserved protein, contains CHAT domain [Function unknown];


Pssm-ID: 444019 [Multi-domain]  Cd Length: 711  Bit Score: 42.26  E-value: 4.34e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 861483604  503 LTAELTTLSATLQQQDQELAGLKQQAQKKQAQLAQSLQQQEQASQGLRHQVEQLSGSLKQKEKQLEEAARELDASRRDHA 582
Cdd:COG4995     2 LALALLALLAALLAALALALLALALLLLLAALAAAALLLLALLALLLALAAAAAAALAAAALALALLAAAALALLLLALA 81

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 861483604  583 QQLATAAKAQETSLRERDAACQQLEALEKEKAAKLEILQQQLQAANEAQDSAQNSVTQAQREKAELSQKVEELHALIEAA 662
Cdd:COG4995    82 LAALALALLAAALALALAAAALAALALLAALLALAAAAALLALLAALALLALLAALAAALAAAAAAALAAALAAAAAAAA 161

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 861483604  663 HQEQCEAQTQVAALEARLKAEQQKATEREKVAQEKAQLQEQLWSLEESLKITKGSLEEEKCRAAAALEEHQHHISEMEAE 742
Cdd:COG4995   162 AAALLALALALAAAALALLALLLAALAAALAAAAAALALLLALLLLAALAAALAAALAALLLALLALAAALLALLLLALL 241

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 861483604  743 SRSLAEQHKQERKELEEEKAKRRGLGVQLQQLAETHQAETKALRQELAKARTSNNMAEREVELLVKEVKTWRKRYEDSQQ 822
Cdd:COG4995   242 ALAAAAAALAAAAAALLALAAALLLLAALAALAAAAAAAALAALALAAALALAAAALALALLLAAAAAAALAALALLLLA 321

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 861483604  823 GETQYGLQEQLTTLKEEYEKSCQELRETKEKMAGIEAHSELQIGQHQSELAQLHANLARALQQVQEKENRAQKLADDLST 902
Cdd:COG4995   322 ALLLLLAALALLALLLLLAAAALLAAALAAALALAAALALALLAALLLLLAALLALLLEALLLLLLALLAALLLLAAALL 401

                         410       420       430       440
                  ....*....|....*....|....*....|....*....|....*....
gi 861483604  903 LQEKMAATSKEVARLEALVRKAGEQQETASLELLKEPPKTRDRESEWVE 951
Cdd:COG4995   402 ALAAAQLLRLLLAALALLLALAAYAAARLALLALIEYIILPDRLYAFVQ 450
SCP-1 pfam05483
Synaptonemal complex protein 1 (SCP-1); Synaptonemal complex protein 1 (SCP-1) is the major ...
 142-492 4.62e-03

Synaptonemal complex protein 1 (SCP-1); Synaptonemal complex protein 1 (SCP-1) is the major component of the transverse filaments of the synaptonemal complex. Synaptonemal complexes are structures that are formed between homologous chromosomes during meiotic prophase.


Pssm-ID: 114219 [Multi-domain]  Cd Length: 787  Bit Score: 42.02  E-value: 4.62e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 861483604   142 NLTEDLEIFLQKVPVSPTCSSTFSEDLSPPSHQ-----AKREVHFLELQKVASSSSGNNFLSGSPASPMGDILQTPQFQM 216
Cdd:pfam05483  293 HLTKELEDIKMSLQRSMSTQKALEEDLQIATKTicqltEEKEAQMEELNKAKAAHSFVVTEFEATTCSLEELLRTEQQRL 372

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 861483604   217 RRLKKQLADERNNRDELELELAEHRKLLTEKDAQISMMQQRI-DRLALLNEKQAASPLEprelEELRGKNESLTFRLHET 295
Cdd:pfam05483  373 EKNEDQLKIITMELQKKSSELEEMTKFKNNKEVELEELKKILaEDEKLLDEKKQFEKIA----EELKGKEQELIFLLQAR 448

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 861483604   296 LKQCQDLKTEKGQMDRKINQLSEENGDLSFKLREFASNLQQLQGALNELTEEHSKATQQWVEKQAHLEKELSTALQDKKC 375
Cdd:pfam05483  449 EKEIHDLEIQLTAIKTSEEHYLKEVEDLKTELEKEKLKNIELTAHCDKLLLENKELTQEASDMTLELKKHQEDIINCKKQ 528

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 861483604   376 LE---EKNEILQGKLSQLEERLAQLPESPRQEKGEVlgdVLQLESLKQEAATLATNNTQLQARVEMLENEQGQKEAQLLG 452
Cdd:pfam05483  529 EErmlKQIENLEEKEMNLRDELESVREEFIQKGDEV---KCKLDKSEENARSIEYEVLKKEKQMKILENKCNNLKKQIEN 605

                          330       340       350       360
                   ....*....|....*....|....*....|....*....|....*
gi 861483604   453 ERSHFEEEKQQLASL-----ITNLQSSISNLSQAKEELEQASQAQ 492
Cdd:pfam05483  606 KNKNIEELHQENKALkkkgsAENKQLNAYEIKVNKLELELASAKQ 650
CwlO1 COG3883
Uncharacterized N-terminal coiled-coil domain of peptidoglycan hydrolase CwlO [Function ...
 593-802 4.65e-03

Uncharacterized N-terminal coiled-coil domain of peptidoglycan hydrolase CwlO [Function unknown];


Pssm-ID: 443091 [Multi-domain]  Cd Length: 379  Bit Score: 41.74  E-value: 4.65e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 861483604  593 ETSLRERDAACQQLEALEKEKAAKLEILQQQLQAANEAQDSAQNSVTQAQREKAELSQKVEELHALIEAAHQE------- 665
Cdd:COG3883    15 DPQIQAKQKELSELQAELEAAQAELDALQAELEELNEEYNELQAELEALQAEIDKLQAEIAEAEAEIEERREElgerara 94

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 861483604  666 QCEAQTQVAALEARLKAEQ-----QKATEREKVAQEKAQLQEQLWSLEESLKITKGSLEEEKCRAAAALEEHQHHISEME 740
Cdd:COG3883    95 LYRSGGSVSYLDVLLGSESfsdflDRLSALSKIADADADLLEELKADKAELEAKKAELEAKLAELEALKAELEAAKAELE 174

                         170       180       190       200       210       220
                  ....*....|....*....|....*....|....*....|....*....|....*....|..
gi 861483604  741 AESRSLAEQHKQERKELEEEKAKRRGLGVQLQQLAETHQAETKALRQELAKARTSNNMAERE 802
Cdd:COG3883   175 AQQAEQEALLAQLSAEEAAAEAQLAELEAELAAAEAAAAAAAAAAAAAAAAAAAAAAAAAAA 236
GumC COG3206
Exopolysaccharide export protein/domain GumC/Wzc1 [Cell wall/membrane/envelope biogenesis];
376-642 4.66e-03

Exopolysaccharide export protein/domain GumC/Wzc1 [Cell wall/membrane/envelope biogenesis];


Pssm-ID: 442439 [Multi-domain]  Cd Length: 687  Bit Score: 41.93  E-value: 4.66e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 861483604  376 LEEKNEILQGKLSQLEERLAQLpespRQEKGEVlgdvlqleSLKQEAATLATNNTQLQARVEMLENEQGQKEAQLlgers 455
Cdd:COG3206   180 LEEQLPELRKELEEAEAALEEF----RQKNGLV--------DLSEEAKLLLQQLSELESQLAEARAELAEAEARL----- 242

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 861483604  456 hfeeekQQLASLITNLQSSISNLSQAkeELEQASQAQGAKLNAQVASLTAELTTLSATLQQQDQELAGLKQQaqkkqaql 535
Cdd:COG3206   243 ------AALRAQLGSGPDALPELLQS--PVIQQLRAQLAELEAELAELSARYTPNHPDVIALRAQIAALRAQ-------- 306

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 861483604  536 aqslqqqeqasqgLRHQVEQLSGSLKQKEKQLEEAARELDASRRDHAQQLATAAKAQetslrerdaacQQLEALEKEKAA 615
Cdd:COG3206   307 -------------LQQEAQRILASLEAELEALQAREASLQAQLAQLEARLAELPELE-----------AELRRLEREVEV 362

                         250       260
                  ....*....|....*....|....*..
gi 861483604  616 KLEILQQQLQAANEAQDSAQNSVTQAQ 642
Cdd:COG3206   363 ARELYESLLQRLEEARLAEALTVGNVR 389
GumC COG3206
Exopolysaccharide export protein/domain GumC/Wzc1 [Cell wall/membrane/envelope biogenesis];
549-720 4.90e-03

Exopolysaccharide export protein/domain GumC/Wzc1 [Cell wall/membrane/envelope biogenesis];


Pssm-ID: 442439 [Multi-domain]  Cd Length: 687  Bit Score: 41.93  E-value: 4.90e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 861483604  549 LRHQVEQLSGSLKQKEKQLEEAARE-----LDASRRDHAQQLATAAKAQETSLRERDAACQQLEALEKEKAAKLEILQQQ 623
Cdd:COG3206   180 LEEQLPELRKELEEAEAALEEFRQKnglvdLSEEAKLLLQQLSELESQLAEARAELAEAEARLAALRAQLGSGPDALPEL 259

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 861483604  624 LQaaNEAQDSAQNSVTQAQREKAELSQKVEELH----------------------ALIEAAHQEQCEAQTQVAALEARLK 681
Cdd:COG3206   260 LQ--SPVIQQLRAQLAELEAELAELSARYTPNHpdvialraqiaalraqlqqeaqRILASLEAELEALQAREASLQAQLA 337

                         170       180       190
                  ....*....|....*....|....*....|....*....
gi 861483604  682 AEQQKATEREKVAQEKAQLQEQLWSLEESLKITKGSLEE 720
Cdd:COG3206   338 QLEARLAELPELEAELRRLEREVEVARELYESLLQRLEE 376
MARTX_Nterm NF012221
MARTX multifunctional-autoprocessing repeats-in-toxin holotoxin N-terminal region; This model ...
 772-1123 4.92e-03

MARTX multifunctional-autoprocessing repeats-in-toxin holotoxin N-terminal region; This model describes the N-terminal 1900 amino acids of MARTX family multifunctional-autoprocessing repeats-in-toxin holotoxins, which contain both repeat regions that facilitate their entry into eukaryotic target cells, and multiple effector domains.


Pssm-ID: 467957 [Multi-domain]  Cd Length: 1848  Bit Score: 42.13  E-value: 4.92e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 861483604  772 QQLAETHQAETKALRQELAKARTSNNMAEREVellvkevkTWR-KRYEDSQQGETQYglQEQLTTLKEEYEKSCQELRET 850
Cdd:NF012221 1452 QDLSNLTAGEVIALSFDFARRAGLSTNNGIEV--------LWNgEVVFASSGDASAW--QQKTLKLTAKAGSNRLEFKGT 1521

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 861483604  851 KEK------MAGIEAHSEL-QIGQHQSELAQLHANLARALQQVQEKENRAQKLADDLstlQEKMAATSKEVARLEALVRK 923
Cdd:NF012221 1522 GHNdglgyiLDNVVATSESsQQADAVSKHAKQDDAAQNALADKERAEADRQRLEQEK---QQQLAAISGSQSQLESTDQN 1598

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 861483604  924 A----GEQQETASLE-------LLKEPPKTRD--RESEWVEEQQGQQLcSTQAALRAMEREAEQM-------GTELEKLR 983
Cdd:NF012221 1599 AletnGQAQRDAILEesravtkELTTLAQGLDalDSQATYAGESGDQW-RNPFAGGLLDRVQEQLddakkisGKQLADAK 1677

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 861483604  984 AALMESQGQQQEERGQQEREVARLTQERGQAEADLAlekAAKAELEMRLQNALNEQQ-AEFANLQEALSRALSEKEGkDQ 1062
Cdd:NF012221 1678 QRHVDNQQKVKDAVAKSEAGVAQGEQNQANAEQDID---DAKADAEKRKDDALAKQNeAQQAESDANAAANDAQSRG-EQ 1753

                         330       340       350       360       370       380
                  ....*....|....*....|....*....|....*....|....*....|....*....|.
gi 861483604 1063 ElSKLCEQEAVQrmelkellqtvEQLKAQLAKKEKEQQQSARGASGENASGMGTQSEAVGK 1123
Cdd:NF012221 1754 D-ASAAENKANQ-----------AQADAKGAKQDESDKPNRQGAAGSGLSGKAYSVEGVAE 1802
CwlO1 COG3883
Uncharacterized N-terminal coiled-coil domain of peptidoglycan hydrolase CwlO [Function ...
 1180-1434 5.29e-03

Uncharacterized N-terminal coiled-coil domain of peptidoglycan hydrolase CwlO [Function unknown];


Pssm-ID: 443091 [Multi-domain]  Cd Length: 379  Bit Score: 41.35  E-value: 5.29e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 861483604 1180 LGYSQAASASAQRELATLRAKAQDHSKAEEEWKAQVARGQQEAVRKGSLISSLEEEVSILNRQVLEKEGESKELKRLVia 1259
Cdd:COG3883     4 LALAAPTPAFADPQIQAKQKELSELQAELEAAQAELDALQAELEELNEEYNELQAELEALQAEIDKLQAEIAEAEAEI-- 81

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 861483604 1260 eSEKSQKLEERLRLLQMETASNSA---------------------RAAERSSALREEVQSLREEVEKQRAASENLRQELA 1318
Cdd:COG3883    82 -EERREELGERARALYRSGGSVSYldvllgsesfsdfldrlsalsKIADADADLLEELKADKAELEAKKAELEAKLAELE 160

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 861483604 1319 SQAERAEELGQELKAWQEkffQKEQALSALQLEHTSTQALVSELLPAKHLCQQLQAEQVAAEKRHREELEQSKQAAGGLR 1398
Cdd:COG3883   161 ALKAELEAAKAELEAQQA---EQEALLAQLSAEEAAAEAQLAELEAELAAAEAAAAAAAAAAAAAAAAAAAAAAAAAAAA 237

                         250       260       270
                  ....*....|....*....|....*....|....*.
gi 861483604 1399 TELMRAQRELGELVPLRQKVAEQERAAQQLRAEKAS 1434
Cdd:COG3883   238 AAAAAAASAAGAGAAGAAGAAAGSAGAAGAAAGAAG 273
46 PHA02562
endonuclease subunit; Provisional
 616-858 5.50e-03

endonuclease subunit; Provisional


Pssm-ID: 222878 [Multi-domain]  Cd Length: 562  Bit Score: 41.54  E-value: 5.50e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 861483604  616 KLEILQQQLQAANEAQDSAQNSVTQAQrekAELSQKVEELHALIEAAHQEQCEAQTQVAALEarlkAEQQKATER-EKVA 694
Cdd:PHA02562  189 KIDHIQQQIKTYNKNIEEQRKKNGENI---ARKQNKYDELVEEAKTIKAEIEELTDELLNLV----MDIEDPSAAlNKLN 261

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 861483604  695 QEKAQLQEQLWSLEESLKItkgsleeekcraaaaLEEHQH------HISEMEAESRSLAEQHKQERKELEEEKAKRRGLG 768
Cdd:PHA02562  262 TAAAKIKSKIEQFQKVIKM---------------YEKGGVcptctqQISEGPDRITKIKDKLKELQHSLEKLDTAIDELE 326

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 861483604  769 VQLQQLAEThQAETKALRQELAKARTSnnmaereVELLVKEVKTWRKRYEDsqqgetqygLQEQLTTLKEEYEKSCQELR 848
Cdd:PHA02562  327 EIMDEFNEQ-SKKLLELKNKISTNKQS-------LITLVDKAKKVKAAIEE---------LQAEFVDNAEELAKLQDELD 389

                         250
                  ....*....|
gi 861483604  849 ETKEKMAGIE 858
Cdd:PHA02562  390 KIVKTKSELV 399
PRK09039 PRK09039
peptidoglycan -binding protein;
549-655 5.92e-03

peptidoglycan -binding protein;


Pssm-ID: 181619 [Multi-domain]  Cd Length: 343  Bit Score: 41.10  E-value: 5.92e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 861483604  549 LRHQVEQLSGSLKQKE---KQLEEAARELDASRRDHAQQLA--TAAKAQETSLRERDAA-----CQQLEALEKEKAAkle 618
Cdd:PRK09039   79 LQDSVANLRASLSAAEaerSRLQALLAELAGAGAAAEGRAGelAQELDSEKQVSARALAqvellNQQIAALRRQLAA--- 155

                          90       100       110
                  ....*....|....*....|....*....|....*....
gi 861483604  619 iLQQQLQAAnEAQDSAQNSVTQA--QREKAELSQKVEEL 655
Cdd:PRK09039  156 -LEAALDAS-EKRDRESQAKIADlgRRLNVALAQRVQEL 192
EmrA COG1566
Multidrug resistance efflux pump EmrA [Defense mechanisms];
1577-1699 6.35e-03

Multidrug resistance efflux pump EmrA [Defense mechanisms];


Pssm-ID: 441174 [Multi-domain]  Cd Length: 331  Bit Score: 41.19  E-value: 6.35e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 861483604 1577 FQAQGGESQQEAQRLQTQLNELQVQLSQKEQAA------EHYKVQMEKAKTHYDAKKQQNQELQEQLQGLEQLQKENKEL 1650
Cdd:COG1566    81 LQAALAQAEAQLAAAEAQLARLEAELGAEAEIAaaeaqlAAAQAQLDLAQRELERYQALYKKGAVSQQELDEARAALDAA 160

                          90       100       110       120
                  ....*....|....*....|....*....|....*....|....*....
gi 861483604 1651 RAEAERLGQELQQAGLKTKEAEQTcRHLTAQVRSLEAQVAHADQQLREL 1699
Cdd:COG1566   161 QAQLEAAQAQLAQAQAGLREEEEL-AAAQAQVAQAEAALAQAELNLART 208
PRK12472 PRK12472
hypothetical protein; Provisional
 568-702 6.77e-03

hypothetical protein; Provisional


Pssm-ID: 237110 [Multi-domain]  Cd Length: 508  Bit Score: 41.39  E-value: 6.77e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 861483604  568 EEAARELD--ASRRDHAQQLATAAKAQETSLRerdAACQQLEALEKEKAAKLEILQQQLQAANEAQDSAQnsvtqAQREK 645
Cdd:PRK12472  193 ETLAREAEdaARAADEAKTAAAAAAREAAPLK---ASLRKLERAKARADAELKRADKALAAAKTDEAKAR-----AEERQ 264

                          90       100       110       120       130
                  ....*....|....*....|....*....|....*....|....*....|....*..
gi 861483604  646 AELSQKVEELHALIEAAHQEQCEAQTQVAALEARLKAEQQKATEREKVAQEKAQLQE 702
Cdd:PRK12472  265 QKAAQQAAEAATQLDTAKADAEAKRAAAAATKEAAKAAAAKKAETAKAATDAKLALE 321
EnvC COG4942
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, ...
 196-449 7.03e-03

Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 443969 [Multi-domain]  Cd Length: 377  Bit Score: 40.90  E-value: 7.03e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 861483604  196 FLSGSPASPMGDILQTPQFQMRRLKKQLADERNNRDELELELAEHRKLLTEKDAQISMMQQRIDRLAllnekqaasplep 275
Cdd:COG4942     9 LLLALAAAAQADAAAEAEAELEQLQQEIAELEKELAALKKEEKALLKQLAALERRIAALARRIRALE------------- 75

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 861483604  276 RELEELRGKNESLTFRLHETLKQCQDLKTEKGQMDRKINQLSEE-------NGDLSFKLREFASNLQQLQGALNELTEEH 348
Cdd:COG4942    76 QELAALEAELAELEKEIAELRAELEAQKEELAELLRALYRLGRQpplalllSPEDFLDAVRRLQYLKYLAPARREQAEEL 155

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 861483604  349 SKATQQWVEKQAHLEKELSTALQDKKCLEEKNEILQGKLSQLEERLAQLPEsprqekgevlgdvlQLESLKQEAATLATN 428
Cdd:COG4942   156 RADLAELAALRAELEAERAELEALLAELEEERAALEALKAERQKLLARLEK--------------ELAELAAELAELQQE 221

                         250       260
                  ....*....|....*....|.
gi 861483604  429 NTQLQARVEMLENEQGQKEAQ 449
Cdd:COG4942   222 AEELEALIARLEAEAAAAAER 242
EnvC COG4942
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, ...
 1317-1568 7.15e-03

Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 443969 [Multi-domain]  Cd Length: 377  Bit Score: 40.90  E-value: 7.15e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 861483604 1317 LASQAERAEELGQELKAWQEKFFQKEQALSALQLEHTSTQALVsellpakhlcQQLQAEQVAAEKRhreeLEQSKQAAGG 1396
Cdd:COG4942    15 AAAQADAAAEAEAELEQLQQEIAELEKELAALKKEEKALLKQL----------AALERRIAALARR----IRALEQELAA 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 861483604 1397 LRTELMRAQRELGELvpLRQKVAEQERAAQQLRA-EKASYAEQLSMLkkahgLLAEENRGLGERANLGRQFLEVELDQAR 1475
Cdd:COG4942    81 LEAELAELEKEIAEL--RAELEAQKEELAELLRAlYRLGRQPPLALL-----LSPEDFLDAVRRLQYLKYLAPARREQAE 153

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 861483604 1476 E--KYIQELAAVRgdaeTRLAEMRQEVQSTTHELEVMTAKYEGAKVKVLEERQRFQEERQKLTAQVEQLEVFQREQTKKV 1553
Cdd:COG4942   154 ElrADLAELAALR----AELEAERAELEALLAELEEERAALEALKAERQKLLARLEKELAELAAELAELQQEAEELEALI 229

                         250
                  ....*....|....*
gi 861483604 1554 EELSKKLADYDQASK 1568
Cdd:COG4942   230 ARLEAEAAAAAERTP 244
MARTX_Nterm NF012221
MARTX multifunctional-autoprocessing repeats-in-toxin holotoxin N-terminal region; This model ...
 253-642 7.82e-03

MARTX multifunctional-autoprocessing repeats-in-toxin holotoxin N-terminal region; This model describes the N-terminal 1900 amino acids of MARTX family multifunctional-autoprocessing repeats-in-toxin holotoxins, which contain both repeat regions that facilitate their entry into eukaryotic target cells, and multiple effector domains.


Pssm-ID: 467957 [Multi-domain]  Cd Length: 1848  Bit Score: 41.74  E-value: 7.82e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 861483604  253 MMQQRIDRLALLNEKQAASPLEpRELEELRGKNESLTFRLHETLKQCQDLK-TEKGQMDRKINQLSEENGDLSFKLREFA 331
Cdd:NF012221 1457 LTAGEVIALSFDFARRAGLSTN-NGIEVLWNGEVVFASSGDASAWQQKTLKlTAKAGSNRLEFKGTGHNDGLGYILDNVV 1535

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 861483604  332 --SNLQQLQGALNELTEEhSKATQQwvekqahlekelstALQDKKCLEEKNEIL-QGKLSQLEE---RLAQLpESPRQEK 405
Cdd:NF012221 1536 atSESSQQADAVSKHAKQ-DDAAQN--------------ALADKERAEADRQRLeQEKQQQLAAisgSQSQL-ESTDQNA 1599

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 861483604  406 GEVLGDVlQLESLKQEAATLATNNTQLQARVEMLeNEQGQKEAQLlGE--RSHF------------EEEKQQLASLITNL 471
Cdd:NF012221 1600 LETNGQA-QRDAILEESRAVTKELTTLAQGLDAL-DSQATYAGES-GDqwRNPFagglldrvqeqlDDAKKISGKQLADA 1676

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 861483604  472 QSSIS-NLSQAKEELEQ--ASQAQGAKLNAQV------ASLTAELTTLSATLQQQDQELAGLKQQAQKKQAQLAQSLQQQ 542
Cdd:NF012221 1677 KQRHVdNQQKVKDAVAKseAGVAQGEQNQANAeqdiddAKADAEKRKDDALAKQNEAQQAESDANAAANDAQSRGEQDAS 1756

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 861483604  543 EQASQGlrHQVEQLSGSLKQKEKqleeaarelDASRRDHAQqlATAAKAQETSLRERDAACQQLEALEKEKAAKL--EIL 620
Cdd:NF012221 1757 AAENKA--NQAQADAKGAKQDES---------DKPNRQGAA--GSGLSGKAYSVEGVAEPGSHINPDSPAAADGRfsEGL 1823

                         410       420
                  ....*....|....*....|..
gi 861483604  621 QQQLQaanEAQDSAQNSVTQAQ 642
Cdd:NF012221 1824 TEQEQ---EALEGATNAVNRLQ 1842
SCP-1 pfam05483
Synaptonemal complex protein 1 (SCP-1); Synaptonemal complex protein 1 (SCP-1) is the major ...
 264-933 8.01e-03

Synaptonemal complex protein 1 (SCP-1); Synaptonemal complex protein 1 (SCP-1) is the major component of the transverse filaments of the synaptonemal complex. Synaptonemal complexes are structures that are formed between homologous chromosomes during meiotic prophase.


Pssm-ID: 114219 [Multi-domain]  Cd Length: 787  Bit Score: 41.25  E-value: 8.01e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 861483604   264 LNEKQAASPLEPRELEELRGKNESLTFRLHETLKQCQDLKTEKGQMDRKINQLSEENGDLSFKLREFA------------ 331
Cdd:pfam05483  108 LQENRKIIEAQRKAIQELQFENEKVSLKLEEEIQENKDLIKENNATRHLCNLLKETCARSAEKTKKYEyereetrqvymd 187

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 861483604   332 --SNLQQLQGALNELT--------EEHSKATQQWvEKQAHLEKELSTALQDK---------KCLEEKN---------EIL 383
Cdd:pfam05483  188 lnNNIEKMILAFEELRvqaenarlEMHFKLKEDH-EKIQHLEEEYKKEINDKekqvsllliQITEKENkmkdltfllEES 266

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 861483604   384 QGKLSQLEERLAQLPESPRQ--EKGEVLGDVLQ--LESLKQEAATLATNNTQLQARVEMLENEQGQKEAQLlgerSHFEE 459
Cdd:pfam05483  267 RDKANQLEEKTKLQDENLKEliEKKDHLTKELEdiKMSLQRSMSTQKALEEDLQIATKTICQLTEEKEAQM----EELNK 342

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 861483604   460 EKQQLASLITNLQSSISNLsqakEELEQASQAQGAKLNAQVASLTAELTTLSATLQQQDQELAGLKQQAQKKQAQLAQSL 539
Cdd:pfam05483  343 AKAAHSFVVTEFEATTCSL----EELLRTEQQRLEKNEDQLKIITMELQKKSSELEEMTKFKNNKEVELEELKKILAEDE 418

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 861483604   540 QQQEQasqglRHQVEQLSGSLKQKEKQLEEAARELDASRRDHAQQLATAAKAQETSLRERDAACQQLEAlEKEKAAKLEI 619
Cdd:pfam05483  419 KLLDE-----KKQFEKIAEELKGKEQELIFLLQAREKEIHDLEIQLTAIKTSEEHYLKEVEDLKTELEK-EKLKNIELTA 492

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 861483604   620 LQQQLQAANE--AQDSAQNSVTQAQREKAELSQKVEELHALIEAAHQEQCEAQTQVAALEARLKAEQQKatEREKVAQEK 697
Cdd:pfam05483  493 HCDKLLLENKelTQEASDMTLELKKHQEDIINCKKQEERMLKQIENLEEKEMNLRDELESVREEFIQKG--DEVKCKLDK 570

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 861483604   698 AQLQEQLWSLEESLKITKGSLEEEKC-RAAAALEEHQHHISEMEAESRSLAEQHKQERKELEEEKAKRRGLGVQLQQLAE 776
Cdd:pfam05483  571 SEENARSIEYEVLKKEKQMKILENKCnNLKKQIENKNKNIEELHQENKALKKKGSAENKQLNAYEIKVNKLELELASAKQ 650

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 861483604   777 THQAETKALRQELAKARTSNnmaerevELLVKEVktwrkryedsqqgETQYGLQEQLTTLKEEYEKSCQelretkEKMAG 856
Cdd:pfam05483  651 KFEEIIDNYQKEIEDKKISE-------EKLLEEV-------------EKAKAIADEAVKLQKEIDKRCQ------HKIAE 704

                          650       660       670       680       690       700       710
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 861483604   857 IEAHSELQIGQHQSELAQLHANLARALQQVQEKENRAQKLADDLSTLQEKMAATSK--EVARLEALVRKAGEQQETASL 933
Cdd:pfam05483  705 MVALMEKHKHQYDKIIEERDSELGLYKNKEQEQSSAKAALEIELSNIKAELLSLKKqlEIEKEEKEKLKMEAKENTAIL 783
DUF5401 pfam17380
Family of unknown function (DUF5401); This is a family of unknown function found in ...
 1150-1444 8.65e-03

Family of unknown function (DUF5401); This is a family of unknown function found in Chromadorea.


Pssm-ID: 375164 [Multi-domain]  Cd Length: 722  Bit Score: 41.26  E-value: 8.65e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 861483604  1150 RSLESERAFHVERDRALETlqgqlEEKARELGYSQAASASAQRELATLRAKAQDHSKAEEEWKAQVARGQQEAVrkGSLI 1229
Cdd:pfam17380  302 RQEKEEKAREVERRRKLEE-----AEKARQAEMDRQAAIYAEQERMAMERERELERIRQEERKRELERIRQEEI--AMEI 374

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 861483604  1230 SSLEEevsiLNRQVLEKEGESKELKRLVIAESEKSQKLEERLRLLQMETASNSARAAERSSALREEVQSLREEVEKQ--- 1306
Cdd:pfam17380  375 SRMRE----LERLQMERQQKNERVRQELEAARKVKILEEERQRKIQQQKVEMEQIRAEQEEARQREVRRLEEERAREmer 450

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 861483604  1307 --------RAASENLRQELASQAERAEELGQELKAWQEKFFQKEQALSalQLEHTSTQALVSELLPAKHLCQQLQAEQVA 1378
Cdd:pfam17380  451 vrleeqerQQQVERLRQQEEERKRKKLELEKEKRDRKRAEEQRRKILE--KELEERKQAMIEEERKRKLLEKEMEERQKA 528

                          250       260       270       280       290       300
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 861483604  1379 -AEKRHREELEQSKqaagglrtelmRAQRELGElvplRQKVAEQERAAQQLRAEKASYAEQLSMLKK 1444
Cdd:pfam17380  529 iYEEERRREAEEER-----------RKQQEMEE----RRRIQEQMRKATEERSRLEAMEREREMMRQ 580
COG4372 COG4372
Uncharacterized protein, contains DUF3084 domain [Function unknown];
1284-1622 9.47e-03

Uncharacterized protein, contains DUF3084 domain [Function unknown];


Pssm-ID: 443500 [Multi-domain]  Cd Length: 370  Bit Score: 40.66  E-value: 9.47e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 861483604 1284 RAAERSSALREEVQSLREEVEKQRAASENLRQELASQAERAEELGQELKAWQEKFFQKEQALSALQLEHTSTQALVsell 1363
Cdd:COG4372    42 KLQEELEQLREELEQAREELEQLEEELEQARSELEQLEEELEELNEQLQAAQAELAQAQEELESLQEEAEELQEEL---- 117

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 861483604 1364 pakhlcQQLQAEQVAAEKRHREELEQSKQAAGGLRTELMRAQRELGELVPLRQKVAEQERAAQQLRAEKASyaEQLSMLK 1443
Cdd:COG4372   118 ------EELQKERQDLEQQRKQLEAQIAELQSEIAEREEELKELEEQLESLQEELAALEQELQALSEAEAE--QALDELL 189

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 861483604 1444 KAHGLLAEENRGLGERANLGRQFLEVELDQAREKYIQELAAVRGDAETRLAEMRQEVQSTTHELEVMTAKYEGAKVKVLE 1523
Cdd:COG4372   190 KEANRNAEKEEELAEAEKLIESLPRELAEELLEAKDSLEAKLGLALSALLDALELEEDKEELLEEVILKEIEELELAILV 269

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 861483604 1524 ERQRFQEERQKLTAQVEQLEVFQREQTKKVEELSKKLADYDQASKVQQQKLKAFQAQGGESQQEAQRLQTQLNELQVQLS 1603
Cdd:COG4372   270 EKDTEEEELEIAALELEALEEAALELKLLALLLNLAALSLIGALEDALLAALLELAKKLELALAILLAELADLLQLLLVG 349

                         330
                  ....*....|....*....
gi 861483604 1604 QKEQAAEHYKVQMEKAKTH 1622
Cdd:COG4372   350 LLDNDVLELLSKGAEAGVA 368
GumC COG3206
Exopolysaccharide export protein/domain GumC/Wzc1 [Cell wall/membrane/envelope biogenesis];
1414-1620 9.75e-03

Exopolysaccharide export protein/domain GumC/Wzc1 [Cell wall/membrane/envelope biogenesis];


Pssm-ID: 442439 [Multi-domain]  Cd Length: 687  Bit Score: 41.16  E-value: 9.75e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 861483604 1414 LRQKVAEQERAAQQLRAEKASYAEQL-------SMLKKAHGLLAEENRGLGERANLGRqfLEVELDQAREKyIQELAAVR 1486
Cdd:COG3206   166 LELRREEARKALEFLEEQLPELRKELeeaeaalEEFRQKNGLVDLSEEAKLLLQQLSE--LESQLAEARAE-LAEAEARL 242

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 861483604 1487 GDAETRLAEMRQEVQSTTH--ELEVMTAKYEGAKVKVLEERQRFQEERQKLTAQVEQLEVFQREqtkKVEELSKKLADYD 1564
Cdd:COG3206   243 AALRAQLGSGPDALPELLQspVIQQLRAQLAELEAELAELSARYTPNHPDVIALRAQIAALRAQ---LQQEAQRILASLE 319

                         170       180       190       200       210
                  ....*....|....*....|....*....|....*....|....*....|....*....
gi 861483604 1565 QASKVQQQKLKAFQAQGGESQQEAQRL---QTQLNELQVQLSQKEQAAEHYKVQMEKAK 1620
Cdd:COG3206   320 AELEALQAREASLQAQLAQLEARLAELpelEAELRRLEREVEVARELYESLLQRLEEAR 378
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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