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Conserved domains on  [gi|530413645|ref|XP_005258253|]
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INO80 complex subunit C isoform X2 [Homo sapiens]

Protein Classification

IES6 family protein( domain architecture ID 7366)

IES6 family protein similar to Saccharomyces cerevisiae chromatin-remodeling complex subunit IES6 and Homo sapiens INO80 complex subunit C

Gene Ontology:  GO:0031011|GO:0006338|GO:0006355|GO:0006281

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
YL1_C super family cl02154
YL1 nuclear protein C-terminal domain; This domain is found in proteins of the YL1 family. ...
 12-132 3.14e-21

YL1 nuclear protein C-terminal domain; This domain is found in proteins of the YL1 family. These proteins have been shown to be DNA-binding and may be a transcription factor. This domain is found in proteins that are not YL1 proteins.


The actual alignment was detected with superfamily member COG5195:

Pssm-ID: 470478 [Multi-domain]  Cd Length: 118  Bit Score: 82.35  E-value: 3.14e-21
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530413645  12 SEFSTGPVEKAAKPLpFKDPNFVhsghggavagKKNRTWKNLKQILASErALPWQLNDPNYFSIDAPPSFKPAKKYSDVS 91
Cdd:COG5195    5 NNNDGGDMKLLKRPW-FKKSTYK----------GKNRRFKTLRQLIPRL-TIENESSKHRYLSIEAPPSVKPRMKYCDVT 72

                         90       100       110       120
                 ....*....|....*....|....*....|....*....|.
gi 530413645  92 GLLANYTDPQSKLRFSTIEEFSYIRRLPSDVVTGYLALRKA 132
Cdd:COG5195   73 GLPAPYTCPNTGLRYHNSEIYKLICELPSGRDQEYLKLREF 113
 
Name Accession Description Interval E-value
COG5195 COG5195
Uncharacterized conserved protein [Function unknown];
12-132 3.14e-21

Uncharacterized conserved protein [Function unknown];


Pssm-ID: 227522 [Multi-domain]  Cd Length: 118  Bit Score: 82.35  E-value: 3.14e-21
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530413645  12 SEFSTGPVEKAAKPLpFKDPNFVhsghggavagKKNRTWKNLKQILASErALPWQLNDPNYFSIDAPPSFKPAKKYSDVS 91
Cdd:COG5195    5 NNNDGGDMKLLKRPW-FKKSTYK----------GKNRRFKTLRQLIPRL-TIENESSKHRYLSIEAPPSVKPRMKYCDVT 72

                         90       100       110       120
                 ....*....|....*....|....*....|....*....|.
gi 530413645  92 GLLANYTDPQSKLRFSTIEEFSYIRRLPSDVVTGYLALRKA 132
Cdd:COG5195   73 GLPAPYTCPNTGLRYHNSEIYKLICELPSGRDQEYLKLREF 113
YL1_C smart00993
YL1 nuclear protein C-terminal domain; This domain is found in proteins of the YL1 family. ...
 86-115 1.41e-09

YL1 nuclear protein C-terminal domain; This domain is found in proteins of the YL1 family. These proteins have been shown to be DNA-binding and may be a transcription factor. This domain is found in proteins that are not YL1 proteins.


Pssm-ID: 198061 [Multi-domain]  Cd Length: 30  Bit Score: 49.82  E-value: 1.41e-09
                           10        20        30
                   ....*....|....*....|....*....|
gi 530413645    86 KYSDVSGLLANYTDPQSKLRFSTIEEFSYI 115
Cdd:smart00993   1 KYCDITGLPARYRDPKTGLRYANAEAYKVI 30
YL1_C pfam08265
YL1 nuclear protein C-terminal domain; This domain is found in proteins of the YL1 family. ...
 87-115 2.64e-08

YL1 nuclear protein C-terminal domain; This domain is found in proteins of the YL1 family. These proteins have been shown to be DNA-binding and may be a transcription factor. This domain is found in proteins that are not YL1 proteins.


Pssm-ID: 462412  Cd Length: 29  Bit Score: 46.59  E-value: 2.64e-08
                          10        20
                  ....*....|....*....|....*....
gi 530413645   87 YSDVSGLLANYTDPQSKLRFSTIEEFSYI 115
Cdd:pfam08265   1 YCDITGLPAKYRDPKTGLPYANVEAYKVI 29
 
Name Accession Description Interval E-value
COG5195 COG5195
Uncharacterized conserved protein [Function unknown];
12-132 3.14e-21

Uncharacterized conserved protein [Function unknown];


Pssm-ID: 227522 [Multi-domain]  Cd Length: 118  Bit Score: 82.35  E-value: 3.14e-21
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530413645  12 SEFSTGPVEKAAKPLpFKDPNFVhsghggavagKKNRTWKNLKQILASErALPWQLNDPNYFSIDAPPSFKPAKKYSDVS 91
Cdd:COG5195    5 NNNDGGDMKLLKRPW-FKKSTYK----------GKNRRFKTLRQLIPRL-TIENESSKHRYLSIEAPPSVKPRMKYCDVT 72

                         90       100       110       120
                 ....*....|....*....|....*....|....*....|.
gi 530413645  92 GLLANYTDPQSKLRFSTIEEFSYIRRLPSDVVTGYLALRKA 132
Cdd:COG5195   73 GLPAPYTCPNTGLRYHNSEIYKLICELPSGRDQEYLKLREF 113
YL1_C smart00993
YL1 nuclear protein C-terminal domain; This domain is found in proteins of the YL1 family. ...
 86-115 1.41e-09

YL1 nuclear protein C-terminal domain; This domain is found in proteins of the YL1 family. These proteins have been shown to be DNA-binding and may be a transcription factor. This domain is found in proteins that are not YL1 proteins.


Pssm-ID: 198061 [Multi-domain]  Cd Length: 30  Bit Score: 49.82  E-value: 1.41e-09
                           10        20        30
                   ....*....|....*....|....*....|
gi 530413645    86 KYSDVSGLLANYTDPQSKLRFSTIEEFSYI 115
Cdd:smart00993   1 KYCDITGLPARYRDPKTGLRYANAEAYKVI 30
YL1_C pfam08265
YL1 nuclear protein C-terminal domain; This domain is found in proteins of the YL1 family. ...
 87-115 2.64e-08

YL1 nuclear protein C-terminal domain; This domain is found in proteins of the YL1 family. These proteins have been shown to be DNA-binding and may be a transcription factor. This domain is found in proteins that are not YL1 proteins.


Pssm-ID: 462412  Cd Length: 29  Bit Score: 46.59  E-value: 2.64e-08
                          10        20
                  ....*....|....*....|....*....
gi 530413645   87 YSDVSGLLANYTDPQSKLRFSTIEEFSYI 115
Cdd:pfam08265   1 YCDITGLPAKYRDPKTGLPYANVEAYKVI 29
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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