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Conserved domains on  [gi|564333752|ref|XP_006231447|]
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cartilage acidic protein 1 isoform X3 [Rattus norvegicus]

Protein Classification

CRTAC1 family protein( domain architecture ID 10608401)

CRTAC1 family protein similar to human cartilage acidic protein 1 (CRTAC1), an extracellular matrix protein of articular cartilage and is a marker for cultured chondrocytes

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
UnbV_ASPIC pfam07593
ASPIC and UnbV; This conserved sequence is found associated with pfam00515 in several ...
 461-522 8.53e-14

ASPIC and UnbV; This conserved sequence is found associated with pfam00515 in several paralogous proteins in Rhodopirellula baltica. It is also found associated with pfam01839 in several eukaryotic integrin-like proteins (e.g. human ASPIC) and in several other bacterial proteins.


:

Pssm-ID: 429555  Cd Length: 66  Bit Score: 66.45  E-value: 8.53e-14
                          10        20        30        40        50        60
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 564333752  461 GAKVVLYTKkSGAHLRIIDGGSGYLCEMEPVAHFGLGR-DEASSVEVTWPDGKM--LSRSVANRE 522
Cdd:pfam07593   1 GARVTVTTA-GGRQYREVTGGRGYLSSSDPRLHFGLGDaTTIDSLEVRWPDGKVqtLENVAANQT 64
FG-GAP_3 pfam13517
FG-GAP-like repeat; This entry represents a repeat found in alpha integrins and related ...
 300-364 6.47e-07

FG-GAP-like repeat; This entry represents a repeat found in alpha integrins and related proteins in which form a 7-fold repeat that adopts a beta-propeller fold. This repeat contains a putative calcium-binding site. These repeats are found in multiple proteins from eukaryotes and bacteria and mediate diverse biological processes at both molecular and cellular levels, such as cell-cell interactions, host-pathogen recognition or innate immune responses.


:

Pssm-ID: 433275 [Multi-domain]  Cd Length: 61  Bit Score: 46.45  E-value: 6.47e-07
                          10        20        30        40        50        60
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 564333752  300 DFNRDGKVDIVYGNWNGPhRLYLQmsaHGKVRFRDIASPKFSTPSPVRTVIAADFDNDQELEVFF 364
Cdd:pfam13517   1 DLDGDGKLDLVVANDGGL-RLYLN---NGDGTFTFITSVSLGGGGGGLSVAVGDLDGDGRLDLLV 61
FG-GAP_3 pfam13517
FG-GAP-like repeat; This entry represents a repeat found in alpha integrins and related ...
 256-310 9.99e-06

FG-GAP-like repeat; This entry represents a repeat found in alpha integrins and related proteins in which form a 7-fold repeat that adopts a beta-propeller fold. This repeat contains a putative calcium-binding site. These repeats are found in multiple proteins from eukaryotes and bacteria and mediate diverse biological processes at both molecular and cellular levels, such as cell-cell interactions, host-pathogen recognition or innate immune responses.


:

Pssm-ID: 433275 [Multi-domain]  Cd Length: 61  Bit Score: 43.37  E-value: 9.99e-06
                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|....*
gi 564333752  256 DIFCdNENGPNFLFHNQGNGTFVDAAASAGVDDPHqhGRGVALADFNRDGKVDIV 310
Cdd:pfam13517   9 DLVV-ANDGGLRLYLNNGDGTFTFITSVSLGGGGG--GLSVAVGDLDGDGRLDLL 60
FG-GAP_3 pfam13517
FG-GAP-like repeat; This entry represents a repeat found in alpha integrins and related ...
 63-133 4.86e-05

FG-GAP-like repeat; This entry represents a repeat found in alpha integrins and related proteins in which form a 7-fold repeat that adopts a beta-propeller fold. This repeat contains a putative calcium-binding site. These repeats are found in multiple proteins from eukaryotes and bacteria and mediate diverse biological processes at both molecular and cellular levels, such as cell-cell interactions, host-pathogen recognition or innate immune responses.


:

Pssm-ID: 433275 [Multi-domain]  Cd Length: 61  Bit Score: 41.44  E-value: 4.86e-05
                          10        20        30        40        50        60        70
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 564333752   63 DVDHDGDFEIVVAGYNGPNLVLkyNRAQSRLVNIAVDERSSPyyalrdrqGNAIGVTACDIDGDGREEIYF 133
Cdd:pfam13517   1 DLDGDGKLDLVVANDGGLRLYL--NNGDGTFTFITSVSLGGG--------GGGLSVAVGDLDGDGRLDLLV 61
 
Name Accession Description Interval E-value
UnbV_ASPIC pfam07593
ASPIC and UnbV; This conserved sequence is found associated with pfam00515 in several ...
 461-522 8.53e-14

ASPIC and UnbV; This conserved sequence is found associated with pfam00515 in several paralogous proteins in Rhodopirellula baltica. It is also found associated with pfam01839 in several eukaryotic integrin-like proteins (e.g. human ASPIC) and in several other bacterial proteins.


Pssm-ID: 429555  Cd Length: 66  Bit Score: 66.45  E-value: 8.53e-14
                          10        20        30        40        50        60
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 564333752  461 GAKVVLYTKkSGAHLRIIDGGSGYLCEMEPVAHFGLGR-DEASSVEVTWPDGKM--LSRSVANRE 522
Cdd:pfam07593   1 GARVTVTTA-GGRQYREVTGGRGYLSSSDPRLHFGLGDaTTIDSLEVRWPDGKVqtLENVAANQT 64
FG-GAP_3 pfam13517
FG-GAP-like repeat; This entry represents a repeat found in alpha integrins and related ...
 300-364 6.47e-07

FG-GAP-like repeat; This entry represents a repeat found in alpha integrins and related proteins in which form a 7-fold repeat that adopts a beta-propeller fold. This repeat contains a putative calcium-binding site. These repeats are found in multiple proteins from eukaryotes and bacteria and mediate diverse biological processes at both molecular and cellular levels, such as cell-cell interactions, host-pathogen recognition or innate immune responses.


Pssm-ID: 433275 [Multi-domain]  Cd Length: 61  Bit Score: 46.45  E-value: 6.47e-07
                          10        20        30        40        50        60
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 564333752  300 DFNRDGKVDIVYGNWNGPhRLYLQmsaHGKVRFRDIASPKFSTPSPVRTVIAADFDNDQELEVFF 364
Cdd:pfam13517   1 DLDGDGKLDLVVANDGGL-RLYLN---NGDGTFTFITSVSLGGGGGGLSVAVGDLDGDGRLDLLV 61
FG-GAP_3 pfam13517
FG-GAP-like repeat; This entry represents a repeat found in alpha integrins and related ...
 256-310 9.99e-06

FG-GAP-like repeat; This entry represents a repeat found in alpha integrins and related proteins in which form a 7-fold repeat that adopts a beta-propeller fold. This repeat contains a putative calcium-binding site. These repeats are found in multiple proteins from eukaryotes and bacteria and mediate diverse biological processes at both molecular and cellular levels, such as cell-cell interactions, host-pathogen recognition or innate immune responses.


Pssm-ID: 433275 [Multi-domain]  Cd Length: 61  Bit Score: 43.37  E-value: 9.99e-06
                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|....*
gi 564333752  256 DIFCdNENGPNFLFHNQGNGTFVDAAASAGVDDPHqhGRGVALADFNRDGKVDIV 310
Cdd:pfam13517   9 DLVV-ANDGGLRLYLNNGDGTFTFITSVSLGGGGG--GLSVAVGDLDGDGRLDLL 60
FG-GAP_3 pfam13517
FG-GAP-like repeat; This entry represents a repeat found in alpha integrins and related ...
 63-133 4.86e-05

FG-GAP-like repeat; This entry represents a repeat found in alpha integrins and related proteins in which form a 7-fold repeat that adopts a beta-propeller fold. This repeat contains a putative calcium-binding site. These repeats are found in multiple proteins from eukaryotes and bacteria and mediate diverse biological processes at both molecular and cellular levels, such as cell-cell interactions, host-pathogen recognition or innate immune responses.


Pssm-ID: 433275 [Multi-domain]  Cd Length: 61  Bit Score: 41.44  E-value: 4.86e-05
                          10        20        30        40        50        60        70
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 564333752   63 DVDHDGDFEIVVAGYNGPNLVLkyNRAQSRLVNIAVDERSSPyyalrdrqGNAIGVTACDIDGDGREEIYF 133
Cdd:pfam13517   1 DLDGDGKLDLVVANDGGLRLYL--NNGDGTFTFITSVSLGGG--------GGGLSVAVGDLDGDGRLDLLV 61
 
Name Accession Description Interval E-value
UnbV_ASPIC pfam07593
ASPIC and UnbV; This conserved sequence is found associated with pfam00515 in several ...
 461-522 8.53e-14

ASPIC and UnbV; This conserved sequence is found associated with pfam00515 in several paralogous proteins in Rhodopirellula baltica. It is also found associated with pfam01839 in several eukaryotic integrin-like proteins (e.g. human ASPIC) and in several other bacterial proteins.


Pssm-ID: 429555  Cd Length: 66  Bit Score: 66.45  E-value: 8.53e-14
                          10        20        30        40        50        60
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 564333752  461 GAKVVLYTKkSGAHLRIIDGGSGYLCEMEPVAHFGLGR-DEASSVEVTWPDGKM--LSRSVANRE 522
Cdd:pfam07593   1 GARVTVTTA-GGRQYREVTGGRGYLSSSDPRLHFGLGDaTTIDSLEVRWPDGKVqtLENVAANQT 64
FG-GAP_3 pfam13517
FG-GAP-like repeat; This entry represents a repeat found in alpha integrins and related ...
 300-364 6.47e-07

FG-GAP-like repeat; This entry represents a repeat found in alpha integrins and related proteins in which form a 7-fold repeat that adopts a beta-propeller fold. This repeat contains a putative calcium-binding site. These repeats are found in multiple proteins from eukaryotes and bacteria and mediate diverse biological processes at both molecular and cellular levels, such as cell-cell interactions, host-pathogen recognition or innate immune responses.


Pssm-ID: 433275 [Multi-domain]  Cd Length: 61  Bit Score: 46.45  E-value: 6.47e-07
                          10        20        30        40        50        60
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 564333752  300 DFNRDGKVDIVYGNWNGPhRLYLQmsaHGKVRFRDIASPKFSTPSPVRTVIAADFDNDQELEVFF 364
Cdd:pfam13517   1 DLDGDGKLDLVVANDGGL-RLYLN---NGDGTFTFITSVSLGGGGGGLSVAVGDLDGDGRLDLLV 61
FG-GAP_3 pfam13517
FG-GAP-like repeat; This entry represents a repeat found in alpha integrins and related ...
 256-310 9.99e-06

FG-GAP-like repeat; This entry represents a repeat found in alpha integrins and related proteins in which form a 7-fold repeat that adopts a beta-propeller fold. This repeat contains a putative calcium-binding site. These repeats are found in multiple proteins from eukaryotes and bacteria and mediate diverse biological processes at both molecular and cellular levels, such as cell-cell interactions, host-pathogen recognition or innate immune responses.


Pssm-ID: 433275 [Multi-domain]  Cd Length: 61  Bit Score: 43.37  E-value: 9.99e-06
                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|....*
gi 564333752  256 DIFCdNENGPNFLFHNQGNGTFVDAAASAGVDDPHqhGRGVALADFNRDGKVDIV 310
Cdd:pfam13517   9 DLVV-ANDGGLRLYLNNGDGTFTFITSVSLGGGGG--GLSVAVGDLDGDGRLDLL 60
FG-GAP_3 pfam13517
FG-GAP-like repeat; This entry represents a repeat found in alpha integrins and related ...
 63-133 4.86e-05

FG-GAP-like repeat; This entry represents a repeat found in alpha integrins and related proteins in which form a 7-fold repeat that adopts a beta-propeller fold. This repeat contains a putative calcium-binding site. These repeats are found in multiple proteins from eukaryotes and bacteria and mediate diverse biological processes at both molecular and cellular levels, such as cell-cell interactions, host-pathogen recognition or innate immune responses.


Pssm-ID: 433275 [Multi-domain]  Cd Length: 61  Bit Score: 41.44  E-value: 4.86e-05
                          10        20        30        40        50        60        70
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 564333752   63 DVDHDGDFEIVVAGYNGPNLVLkyNRAQSRLVNIAVDERSSPyyalrdrqGNAIGVTACDIDGDGREEIYF 133
Cdd:pfam13517   1 DLDGDGKLDLVVANDGGLRLYL--NNGDGTFTFITSVSLGGG--------GGGLSVAVGDLDGDGRLDLLV 61
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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