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Conserved domains on  [gi|564335423|ref|XP_006232056|]
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tetratricopeptide repeat protein 33 isoform X2 [Rattus norvegicus]

Protein Classification

tetratricopeptide repeat protein( domain architecture ID 708416)

tetratricopeptide repeat (TPR) protein may adopt a right-handed helical structure with an amphipathic channel and may function as an interaction scaffold in the formation of multi-protein complexes

CATH:  1.25.40.10
Gene Ontology:  GO:0005515
PubMed:  10517866|30708253
SCOP:  3001345

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
Spy super family cl27809
Predicted O-linked N-acetylglucosamine transferase, SPINDLY family [Posttranslational ...
 20-210 1.32e-13

Predicted O-linked N-acetylglucosamine transferase, SPINDLY family [Posttranslational modification, protein turnover, chaperones];


The actual alignment was detected with superfamily member COG3914:

Pssm-ID: 443119 [Multi-domain]  Cd Length: 658  Bit Score: 70.02  E-value: 1.32e-13
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564335423  20 QQFEAEAADEKGAAESEDGNWLHASKRRKETLQEGCKQRSKQ------LKDEGAHLAENKRYQEAIRKWDEALQLTPEDA 93
Cdd:COG3914   67 AAAAAAALLLLAALLELAALLLQALGRYEEALALYRRALALNpdnaeaLFNLGNLLLALGRLEEALAALRRALALNPDFA 146

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564335423  94 TLYEMKSQVLMSLHEMFPAVHAAEMAVKRNPHSWESWQTLGRAQLGLGEIVLAIRSFQVALHIYPMNPEIWKEDLSWARK 173
Cdd:COG3914  147 EAYLNLGEALRRLGRLEEAIAALRRALELDPDNAEALNNLGNALQDLGRLEEAIAAYRRALELDPDNADAHSNLLFALRQ 226

                        170       180       190
                 ....*....|....*....|....*....|....*..
gi 564335423 174 LQEQQKVAQRIEKKEIPPEGPDLSPGAIPDYDFESDE 210
Cdd:COG3914  227 ACDWEVYDRFEELLAALARGPSELSPFALLYLPDDDP 263
 
Name Accession Description Interval E-value
Spy COG3914
Predicted O-linked N-acetylglucosamine transferase, SPINDLY family [Posttranslational ...
 20-210 1.32e-13

Predicted O-linked N-acetylglucosamine transferase, SPINDLY family [Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 443119 [Multi-domain]  Cd Length: 658  Bit Score: 70.02  E-value: 1.32e-13
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564335423  20 QQFEAEAADEKGAAESEDGNWLHASKRRKETLQEGCKQRSKQ------LKDEGAHLAENKRYQEAIRKWDEALQLTPEDA 93
Cdd:COG3914   67 AAAAAAALLLLAALLELAALLLQALGRYEEALALYRRALALNpdnaeaLFNLGNLLLALGRLEEALAALRRALALNPDFA 146

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564335423  94 TLYEMKSQVLMSLHEMFPAVHAAEMAVKRNPHSWESWQTLGRAQLGLGEIVLAIRSFQVALHIYPMNPEIWKEDLSWARK 173
Cdd:COG3914  147 EAYLNLGEALRRLGRLEEAIAALRRALELDPDNAEALNNLGNALQDLGRLEEAIAAYRRALELDPDNADAHSNLLFALRQ 226

                        170       180       190
                 ....*....|....*....|....*....|....*..
gi 564335423 174 LQEQQKVAQRIEKKEIPPEGPDLSPGAIPDYDFESDE 210
Cdd:COG3914  227 ACDWEVYDRFEELLAALARGPSELSPFALLYLPDDDP 263
 
Name Accession Description Interval E-value
Spy COG3914
Predicted O-linked N-acetylglucosamine transferase, SPINDLY family [Posttranslational ...
 20-210 1.32e-13

Predicted O-linked N-acetylglucosamine transferase, SPINDLY family [Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 443119 [Multi-domain]  Cd Length: 658  Bit Score: 70.02  E-value: 1.32e-13
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564335423  20 QQFEAEAADEKGAAESEDGNWLHASKRRKETLQEGCKQRSKQ------LKDEGAHLAENKRYQEAIRKWDEALQLTPEDA 93
Cdd:COG3914   67 AAAAAAALLLLAALLELAALLLQALGRYEEALALYRRALALNpdnaeaLFNLGNLLLALGRLEEALAALRRALALNPDFA 146

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564335423  94 TLYEMKSQVLMSLHEMFPAVHAAEMAVKRNPHSWESWQTLGRAQLGLGEIVLAIRSFQVALHIYPMNPEIWKEDLSWARK 173
Cdd:COG3914  147 EAYLNLGEALRRLGRLEEAIAALRRALELDPDNAEALNNLGNALQDLGRLEEAIAAYRRALELDPDNADAHSNLLFALRQ 226

                        170       180       190
                 ....*....|....*....|....*....|....*..
gi 564335423 174 LQEQQKVAQRIEKKEIPPEGPDLSPGAIPDYDFESDE 210
Cdd:COG3914  227 ACDWEVYDRFEELLAALARGPSELSPFALLYLPDDDP 263
Spy COG3914
Predicted O-linked N-acetylglucosamine transferase, SPINDLY family [Posttranslational ...
 20-185 8.06e-13

Predicted O-linked N-acetylglucosamine transferase, SPINDLY family [Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 443119 [Multi-domain]  Cd Length: 658  Bit Score: 67.71  E-value: 8.06e-13
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564335423  20 QQFEAEAADEKGAAESEDGNWLHASKRRKETLQEGCKQRSKQLKDEGAHLAENKRYQEAIRKWDEALQLTPEDATLYEMK 99
Cdd:COG3914   39 AALGLALLLLAALAEAAAAALLALAAGEAAAAAAALLLLAALLELAALLLQALGRYEEALALYRRALALNPDNAEALFNL 118

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564335423 100 SQVLMSLHEMFPAVHAAEMAVKRNPHSWESWQTLGRAQLGLGEIVLAIRSFQVALHIYPMNPEIWkedLSWARKLQEQQK 179
Cdd:COG3914  119 GNLLLALGRLEEALAALRRALALNPDFAEAYLNLGEALRRLGRLEEAIAALRRALELDPDNAEAL---NNLGNALQDLGR 195


                 ....*.
gi 564335423 180 VAQRIE 185
Cdd:COG3914  196 LEEAIA 201
BepA COG4783
Outer membrane protein chaperone/metalloprotease BepA/YfgC, contains M48 and TPR domains [Cell ...
 57-164 7.11e-12

Outer membrane protein chaperone/metalloprotease BepA/YfgC, contains M48 and TPR domains [Cell wall/membrane/envelope biogenesis, Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 443813 [Multi-domain]  Cd Length: 139  Bit Score: 61.36  E-value: 7.11e-12
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564335423  57 QRSKQLKDEGAHLAENKRYQEAIRKWDEALQLTPEDATLYEMKSQVLMSLHEMFPAVHAAEMAVKRNPHSWESWQTLGRA 136
Cdd:COG4783    2 ACAEALYALAQALLLAGDYDEAEALLEKALELDPDNPEAFALLGEILLQLGDLDEAIVLLHEALELDPDEPEARLNLGLA 81

                         90       100
                 ....*....|....*....|....*...
gi 564335423 137 QLGLGEIVLAIRSFQVALHIYPMNPEIW 164
Cdd:COG4783   82 LLKAGDYDEALALLEKALKLDPEHPEAY 109
TPR COG0457
Tetratricopeptide (TPR) repeat [General function prediction only];
66-164 1.18e-10

Tetratricopeptide (TPR) repeat [General function prediction only];


Pssm-ID: 440225 [Multi-domain]  Cd Length: 245  Bit Score: 60.02  E-value: 1.18e-10
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564335423  66 GAHLAENKRYQEAIRKWDEALQLTPEDATLYEMKSQVLMSLHEMFPAVHAAEMAVKRNPHSWESWQTLGRAQLGLGEIVL 145
Cdd:COG0457   15 GLAYRRLGRYEEAIEDYEKALELDPDDAEALYNLGLAYLRLGRYEEALADYEQALELDPDDAEALNNLGLALQALGRYEE 94

                         90
                 ....*....|....*....
gi 564335423 146 AIRSFQVALHIYPMNPEIW 164
Cdd:COG0457   95 ALEDYDKALELDPDDAEAL 113
TPR COG0457
Tetratricopeptide (TPR) repeat [General function prediction only];
66-189 1.34e-09

Tetratricopeptide (TPR) repeat [General function prediction only];


Pssm-ID: 440225 [Multi-domain]  Cd Length: 245  Bit Score: 56.94  E-value: 1.34e-09
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564335423  66 GAHLAENKRYQEAIRKWDEALQLTPEDATLYEMKSQVLMSLHEMFPAVHAAEMAVKRNPHSWESWQTLGRAQLGLGEIVL 145
Cdd:COG0457   49 GLAYLRLGRYEEALADYEQALELDPDDAEALNNLGLALQALGRYEEALEDYDKALELDPDDAEALYNLGLALLELGRYDE 128

                         90       100       110       120
                 ....*....|....*....|....*....|....*....|....
gi 564335423 146 AIRSFQVALHIYPMNPEIWkEDLSWARKLQEQQKVAQRIEKKEI 189
Cdd:COG0457  129 AIEAYERALELDPDDADAL-YNLGIALEKLGRYEEALELLEKLE 171
BepA COG4783
Outer membrane protein chaperone/metalloprotease BepA/YfgC, contains M48 and TPR domains [Cell ...
 69-160 4.11e-09

Outer membrane protein chaperone/metalloprotease BepA/YfgC, contains M48 and TPR domains [Cell wall/membrane/envelope biogenesis, Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 443813 [Multi-domain]  Cd Length: 139  Bit Score: 53.66  E-value: 4.11e-09
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564335423  69 LAENKRYQEAIRKWDEALQLTPEDATLYEMKSQVLMSLHEMFPAVHAAEMAVKRNPHSWESWQTLGRAQLGLGEIVLAIR 148
Cdd:COG4783   48 LLQLGDLDEAIVLLHEALELDPDEPEARLNLGLALLKAGDYDEALALLEKALKLDPEHPEAYLRLARAYRALGRPDEAIA 127

                         90
                 ....*....|..
gi 564335423 149 SFQVALHIYPMN 160
Cdd:COG4783  128 ALEKALELDPDD 139
NrfG COG4235
Cytochrome c-type biogenesis protein CcmH/NrfG [Energy production and conversion, ...
 66-162 1.17e-08

Cytochrome c-type biogenesis protein CcmH/NrfG [Energy production and conversion, Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 443378 [Multi-domain]  Cd Length: 131  Bit Score: 52.32  E-value: 1.17e-08
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564335423  66 GAHLAENKRYQEAIRKWDEALQLTPEDATLYEMKSQVLMSLHEMFPAVHAAEMAVKRNPHSWESWQTLGRAQLGLGEIVL 145
Cdd:COG4235   24 GRAYLRLGRYDEALAAYEKALRLDPDNADALLDLAEALLAAGDTEEAEELLERALALDPDNPEALYLLGLAAFQQGDYAE 103

                         90
                 ....*....|....*..
gi 564335423 146 AIRSFQVALHIYPMNPE 162
Cdd:COG4235  104 AIAAWQKLLALLPADAP 120
TadD COG5010
Flp pilus assembly protein TadD, contains TPR repeats [Intracellular trafficking, secretion, ...
 69-159 3.29e-08

Flp pilus assembly protein TadD, contains TPR repeats [Intracellular trafficking, secretion, and vesicular transport, Extracellular structures];


Pssm-ID: 444034 [Multi-domain]  Cd Length: 155  Bit Score: 51.50  E-value: 3.29e-08
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564335423  69 LAENKRYQEAIRKWDEALQLTPEDATLYEMKSQVLMSLHEMFPAVHAAEMAVKRNPHSWESWQTLGRAQLGLGEIVLAIR 148
Cdd:COG5010   64 YNKLGDFEESLALLEQALQLDPNNPELYYNLALLYSRSGDKDEAKEYYEKALALSPDNPNAYSNLAALLLSLGQDDEAKA 143

                         90
                 ....*....|.
gi 564335423 149 SFQVALHIYPM 159
Cdd:COG5010  144 ALQRALGTSPL 154
TPR COG0457
Tetratricopeptide (TPR) repeat [General function prediction only];
66-186 1.32e-07

Tetratricopeptide (TPR) repeat [General function prediction only];


Pssm-ID: 440225 [Multi-domain]  Cd Length: 245  Bit Score: 51.16  E-value: 1.32e-07
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564335423  66 GAHLAENKRYQEAIRKWDEALQLTPEDATLYEMKSQVLMSLHEMFPAVHAAEMAVKRNPHSWESWQTLGRAQLGLGEIVL 145
Cdd:COG0457   83 GLALQALGRYEEALEDYDKALELDPDDAEALYNLGLALLELGRYDEAIEAYERALELDPDDADALYNLGIALEKLGRYEE 162

                         90       100       110       120
                 ....*....|....*....|....*....|....*....|.
gi 564335423 146 AIRSFQVALHIYPMNPEIWKEDLSWARKLQEQQKVAQRIEK 186
Cdd:COG0457  163 ALELLEKLEAAALAALLAAALGEAALALAAAEVLLALLLAL 203
PilF COG3063
Type IV pilus assembly protein PilF/PilW [Cell motility, Extracellular structures];
69-158 3.27e-07

Type IV pilus assembly protein PilF/PilW [Cell motility, Extracellular structures];


Pssm-ID: 442297 [Multi-domain]  Cd Length: 94  Bit Score: 47.47  E-value: 3.27e-07
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564335423  69 LAENKRYQEAIRKWDEALQLTPEDATLYEMKSQVLMSLHEmFPAVHAAEMAVKRNPHSWESWQTLGRAQLGLGEIVLAIR 148
Cdd:COG3063    2 YLKLGDLEEAEEYYEKALELDPDNADALNNLGLLLLEQGR-YDEAIALEKALKLDPNNAEALLNLAELLLELGDYDEALA 80

                         90
                 ....*....|
gi 564335423 149 SFQVALHIYP 158
Cdd:COG3063   81 YLERALELDP 90
NlpI COG4785
Lipoprotein NlpI, contains TPR repeats [Cell wall/membrane/envelope biogenesis];
62-162 7.31e-07

Lipoprotein NlpI, contains TPR repeats [Cell wall/membrane/envelope biogenesis];


Pssm-ID: 443815 [Multi-domain]  Cd Length: 223  Bit Score: 48.76  E-value: 7.31e-07
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564335423  62 LKDEGAHLAENKRYQEAIRKWDEALQLTPEDATLYEMKSQVLMSLHEMFPAVHAAEMAVKRNPHSWESWQTLGRAQLGLG 141
Cdd:COG4785   76 YYERGVAYDSLGDYDLAIADFDQALELDPDLAEAYNNRGLAYLLLGDYDAALEDFDRALELDPDYAYAYLNRGIALYYLG 155

                         90       100
                 ....*....|....*....|.
gi 564335423 142 EIVLAIRSFQVALHIYPMNPE 162
Cdd:COG4785  156 RYELAIADLEKALELDPNDPE 176
TadD COG5010
Flp pilus assembly protein TadD, contains TPR repeats [Intracellular trafficking, secretion, ...
 74-189 9.16e-07

Flp pilus assembly protein TadD, contains TPR repeats [Intracellular trafficking, secretion, and vesicular transport, Extracellular structures];


Pssm-ID: 444034 [Multi-domain]  Cd Length: 155  Bit Score: 47.65  E-value: 9.16e-07
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564335423  74 RYQEAIRKWDEALQLTPEDATLYEMKSQVLMSLHEMFPAVHAAEMAVKRNPHSWESWQTLGRAQLGLGEIVLAIRSFQVA 153
Cdd:COG5010   35 NNTKEDELAAAGRDKLAKAFAIESPSDNLYNKLGDFEESLALLEQALQLDPNNPELYYNLALLYSRSGDKDEAKEYYEKA 114

                         90       100       110
                 ....*....|....*....|....*....|....*.
gi 564335423 154 LHIYPMNPEIWkEDLSWARKLQEQQKVAQRIEKKEI 189
Cdd:COG5010  115 LALSPDNPNAY-SNLAALLLSLGQDDEAKAALQRAL 149
NrfG COG4235
Cytochrome c-type biogenesis protein CcmH/NrfG [Energy production and conversion, ...
 77-164 1.81e-06

Cytochrome c-type biogenesis protein CcmH/NrfG [Energy production and conversion, Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 443378 [Multi-domain]  Cd Length: 131  Bit Score: 46.15  E-value: 1.81e-06
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564335423  77 EAIRKWDEALQLTPEDATLYEMKSQVLMSLHEMFPAVHAAEMAVKRNPHSWESWQTLGRAQLGLGEIVLAIRSFQVALHI 156
Cdd:COG4235    1 EAIARLRQALAANPNDAEGWLLLGRAYLRLGRYDEALAAYEKALRLDPDNADALLDLAEALLAAGDTEEAEELLERALAL 80


                 ....*...
gi 564335423 157 YPMNPEIW 164
Cdd:COG4235   81 DPDNPEAL 88
LapB COG2956
Lipopolysaccharide biosynthesis regulator YciM/LapB, contains six TPR domains and a C-terminal ...
 65-186 2.65e-06

Lipopolysaccharide biosynthesis regulator YciM/LapB, contains six TPR domains and a C-terminal metal-binding domain [Cell wall/membrane/envelope biogenesis];


Pssm-ID: 442196 [Multi-domain]  Cd Length: 275  Bit Score: 47.42  E-value: 2.65e-06
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564335423  65 EGAHLAENKRYQEAIRKWDEALQLTPEDATLYEMKSQVLMSLHEMFPAVHAAEMAVKRNPHSWESWQTLGRAQLGLGEIV 144
Cdd:COG2956   14 KGLNYLLNGQPDKAIDLLEEALELDPETVEAHLALGNLYRRRGEYDRAIRIHQKLLERDPDRAEALLELAQDYLKAGLLD 93

                         90       100       110       120
                 ....*....|....*....|....*....|....*....|....*
gi 564335423 145 LAIRSFQVALHIYPMNPEIWKEDLSWARKLQEQQK---VAQRIEK 186
Cdd:COG2956   94 RAEELLEKLLELDPDDAEALRLLAEIYEQEGDWEKaieVLERLLK 138
LapB COG2956
Lipopolysaccharide biosynthesis regulator YciM/LapB, contains six TPR domains and a C-terminal ...
 66-186 6.78e-06

Lipopolysaccharide biosynthesis regulator YciM/LapB, contains six TPR domains and a C-terminal metal-binding domain [Cell wall/membrane/envelope biogenesis];


Pssm-ID: 442196 [Multi-domain]  Cd Length: 275  Bit Score: 46.26  E-value: 6.78e-06
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564335423  66 GAHLAENKRYQEAIRKWDEALQLTPEDATLYEMKSQVLMSLHEMFPAVHAAEMAVKRNPHSWESWQTLGRAQLGLGEIVL 145
Cdd:COG2956  117 AEIYEQEGDWEKAIEVLERLLKLGPENAHAYCELAELYLEQGDYDEAIEALEKALKLDPDCARALLLLAELYLEQGDYEE 196

                         90       100       110       120
                 ....*....|....*....|....*....|....*....|.
gi 564335423 146 AIRSFQVALHIYPMNPEIWKEDLSWARKLQEQQKVAQRIEK 186
Cdd:COG2956  197 AIAALERALEQDPDYLPALPRLAELYEKLGDPEEALELLRK 237
LapB COG2956
Lipopolysaccharide biosynthesis regulator YciM/LapB, contains six TPR domains and a C-terminal ...
 66-185 2.57e-05

Lipopolysaccharide biosynthesis regulator YciM/LapB, contains six TPR domains and a C-terminal metal-binding domain [Cell wall/membrane/envelope biogenesis];


Pssm-ID: 442196 [Multi-domain]  Cd Length: 275  Bit Score: 44.33  E-value: 2.57e-05
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564335423  66 GAHLAENKRYQEAIRKWDEALQLTPEDATLYEMKSQVLMSLHEMFPAVHAAEMAVKRNPHSWESWQTLGRAQLGLGEIVL 145
Cdd:COG2956  151 AELYLEQGDYDEAIEALEKALKLDPDCARALLLLAELYLEQGDYEEAIAALERALEQDPDYLPALPRLAELYEKLGDPEE 230

                         90       100       110       120
                 ....*....|....*....|....*....|....*....|
gi 564335423 146 AIRSFQVALHIYPMNPEIwkedLSWARKLQEQQKVAQRIE 185
Cdd:COG2956  231 ALELLRKALELDPSDDLL----LALADLLERKEGLEAALA 266
TPR COG0457
Tetratricopeptide (TPR) repeat [General function prediction only];
86-164 3.92e-05

Tetratricopeptide (TPR) repeat [General function prediction only];


Pssm-ID: 440225 [Multi-domain]  Cd Length: 245  Bit Score: 43.84  E-value: 3.92e-05
                         10        20        30        40        50        60        70
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 564335423  86 LQLTPEDATLYEMKSQVLMSLHEMFPAVHAAEMAVKRNPHSWESWQTLGRAQLGLGEIVLAIRSFQVALHIYPMNPEIW 164
Cdd:COG0457    1 LELDPDDAEAYNNLGLAYRRLGRYEEAIEDYEKALELDPDDAEALYNLGLAYLRLGRYEEALADYEQALELDPDDAEAL 79
BepA COG4783
Outer membrane protein chaperone/metalloprotease BepA/YfgC, contains M48 and TPR domains [Cell ...
 66-124 8.32e-04

Outer membrane protein chaperone/metalloprotease BepA/YfgC, contains M48 and TPR domains [Cell wall/membrane/envelope biogenesis, Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 443813 [Multi-domain]  Cd Length: 139  Bit Score: 38.63  E-value: 8.32e-04
                         10        20        30        40        50
                 ....*....|....*....|....*....|....*....|....*....|....*....
gi 564335423  66 GAHLAENKRYQEAIRKWDEALQLTPEDATLYEMKSQVLMSLHEMFPAVHAAEMAVKRNP 124
Cdd:COG4783   79 GLALLKAGDYDEALALLEKALKLDPEHPEAYLRLARAYRALGRPDEAIAALEKALELDP 137
LapB COG2956
Lipopolysaccharide biosynthesis regulator YciM/LapB, contains six TPR domains and a C-terminal ...
 73-185 1.21e-03

Lipopolysaccharide biosynthesis regulator YciM/LapB, contains six TPR domains and a C-terminal metal-binding domain [Cell wall/membrane/envelope biogenesis];


Pssm-ID: 442196 [Multi-domain]  Cd Length: 275  Bit Score: 39.33  E-value: 1.21e-03
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564335423  73 KRYQEAIRKWDEALQLTPEDATLYEMKSQVLMSLHEMFPAVHAAEMAVKRNPHSWESWQTLGRAQLGLGEIVLAIRSFQV 152
Cdd:COG2956   56 GEYDRAIRIHQKLLERDPDRAEALLELAQDYLKAGLLDRAEELLEKLLELDPDDAEALRLLAEIYEQEGDWEKAIEVLER 135

                         90       100       110
                 ....*....|....*....|....*....|...
gi 564335423 153 ALHIYPMNPEIWKEdlsWARKLQEQQKVAQRIE 185
Cdd:COG2956  136 LLKLGPENAHAYCE---LAELYLEQGDYDEAIE 165
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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